Guide to the Human Genome
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Search of human proteins with 226437602

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226437602 NK1 homeobox 2 [Homo sapiens]
         (310 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226437602 NK1 homeobox 2 [Homo sapiens]                            632   0.0  
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                 619   e-177
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                 619   e-177
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                 619   e-177
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                 184   7e-47
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]               184   7e-47
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                 175   5e-44
gi|118582284 msh homeobox 1 [Homo sapiens]                             94   2e-19
gi|89257348 homeo box HB9 [Homo sapiens]                               93   3e-19
gi|4758168 distal-less homeobox 2 [Homo sapiens]                       92   6e-19
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       89   5e-18
gi|24497589 aristaless related homeobox [Homo sapiens]                 88   8e-18
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     88   1e-17
gi|13273315 homeobox B4 [Homo sapiens]                                 87   2e-17
gi|84570137 homeobox B3 [Homo sapiens]                                 87   2e-17
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    86   5e-17
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]              86   5e-17
gi|14149728 BarH-like homeobox 1 [Homo sapiens]                        85   7e-17
gi|6633798 BarH-like homeobox 2 [Homo sapiens]                         85   9e-17
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        84   1e-16
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    84   1e-16
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]             84   1e-16
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       84   2e-16
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       84   2e-16
gi|148613882 homeobox A4 [Homo sapiens]                                84   2e-16
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               84   2e-16
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    82   8e-16
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           81   1e-15
gi|24497538 homeobox C4 [Homo sapiens]                                 80   2e-15
gi|24497540 homeobox C4 [Homo sapiens]                                 80   2e-15

>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score =  632 bits (1629), Expect = 0.0
 Identities = 310/310 (100%), Positives = 310/310 (100%)

Query: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60
           MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS
Sbjct: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60

Query: 61  SRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDA 120
           SRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDA
Sbjct: 61  SRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDA 120

Query: 121 PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN 180
           PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN
Sbjct: 121 PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN 180

Query: 181 KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGA 240
           KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGA
Sbjct: 181 KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGA 240

Query: 241 AGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPS 300
           AGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPS
Sbjct: 241 AGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPS 300

Query: 301 YLTPFYAPRL 310
           YLTPFYAPRL
Sbjct: 301 YLTPFYAPRL 310


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score =  619 bits (1596), Expect = e-177
 Identities = 310/332 (93%), Positives = 310/332 (93%), Gaps = 22/332 (6%)

Query: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60
           MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS
Sbjct: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60

Query: 61  SRDPVRQLETP----------------------DAAGPGAGQASPLEGSEAEEEEDAEDP 98
           SRDPVRQLETP                      DAAGPGAGQASPLEGSEAEEEEDAEDP
Sbjct: 61  SRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLEGSEAEEEEDAEDP 120

Query: 99  RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 158
           RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP
Sbjct: 121 RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 180

Query: 159 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 218
           NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW
Sbjct: 181 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 240

Query: 219 KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS 278
           KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS
Sbjct: 241 KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS 300

Query: 279 AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL 310
           AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL
Sbjct: 301 AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL 332


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score =  619 bits (1596), Expect = e-177
 Identities = 310/332 (93%), Positives = 310/332 (93%), Gaps = 22/332 (6%)

Query: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60
           MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS
Sbjct: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60

Query: 61  SRDPVRQLETP----------------------DAAGPGAGQASPLEGSEAEEEEDAEDP 98
           SRDPVRQLETP                      DAAGPGAGQASPLEGSEAEEEEDAEDP
Sbjct: 61  SRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLEGSEAEEEEDAEDP 120

Query: 99  RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 158
           RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP
Sbjct: 121 RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 180

Query: 159 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 218
           NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW
Sbjct: 181 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 240

Query: 219 KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS 278
           KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS
Sbjct: 241 KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS 300

Query: 279 AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL 310
           AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL
Sbjct: 301 AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL 332


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score =  619 bits (1596), Expect = e-177
 Identities = 310/332 (93%), Positives = 310/332 (93%), Gaps = 22/332 (6%)

Query: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60
           MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS
Sbjct: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60

Query: 61  SRDPVRQLETP----------------------DAAGPGAGQASPLEGSEAEEEEDAEDP 98
           SRDPVRQLETP                      DAAGPGAGQASPLEGSEAEEEEDAEDP
Sbjct: 61  SRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLEGSEAEEEEDAEDP 120

Query: 99  RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 158
           RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP
Sbjct: 121 RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 180

Query: 159 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 218
           NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW
Sbjct: 181 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 240

Query: 219 KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS 278
           KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS
Sbjct: 241 KKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPS 300

Query: 279 AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL 310
           AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL
Sbjct: 301 AASFPLTAAAPGSPFAPFLGPSYLTPFYAPRL 332


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score =  184 bits (468), Expect = 7e-47
 Identities = 153/384 (39%), Positives = 185/384 (48%), Gaps = 84/384 (21%)

Query: 7   GGAKAAPSHHKISFSVLDILDPQKFTR------------------------AALPAVRPA 42
           G A+ A      SFSVLDILDP KF                          A  PA    
Sbjct: 435 GAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGR 494

Query: 43  PREA----RKSLAEVEAGKDASSRDP--------VRQLETPDAAG---------PGAGQA 81
           P  A    R++LA    G  A+  +P          + ET D  G         P A   
Sbjct: 495 PPRAEELERRALAGA-GGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSG 553

Query: 82  SPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLA-------------RSPDAPAGALASG 128
             +   E ++E++A +    R  E A     GL               SP A     A+ 
Sbjct: 554 DEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAP 613

Query: 129 EPCED--------GG----GGPVRSPPGSPGSPRPRRRRL--EPNCAKPRRARTAFTYEQ 174
            P E+        GG    GG   +P G+  + +P+R+R   +    KPRRARTAFTYEQ
Sbjct: 614 GPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQ 673

Query: 175 LVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQV-GG 233
           LVALENKF+ATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD +A   GG
Sbjct: 674 LVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGG 733

Query: 234 GAPQPGAAGGGG--GGGSGGSPGPPGTGALHFQ---TFPSYSAANVLFPSAASFPLTAAA 288
           G P PGA  G G  GG S  SP PP    L       +P++    ++  +   F L++ A
Sbjct: 734 GGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGLVCAAQLPF-LSSPA 792

Query: 289 PGSPFAPFLG-PSYLTP-FYAPRL 310
             SPF   LG  +Y  P FYAP L
Sbjct: 793 VLSPFV--LGSQTYGAPAFYAPHL 814


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score =  184 bits (468), Expect = 7e-47
 Identities = 155/387 (40%), Positives = 186/387 (48%), Gaps = 90/387 (23%)

Query: 7   GGAKAAPSHHKISFSVLDILDPQKFTR------------------------AALPAVRPA 42
           G A+ A      SFSVLDILDP KF                          A  PA    
Sbjct: 32  GAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGR 91

Query: 43  PREA----RKSLAEVEAGKDASSRDP--------VRQLETPDAAG---------PGAGQA 81
           P  A    R++LA    G  A+  +P          + ET D  G         P A   
Sbjct: 92  PPRAEELERRALAGA-GGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSG 150

Query: 82  SPLEGSEAEEEEDAEDPRRPRLRERAARLLPGL---------ARSPDAPAGA-------- 124
             +   E ++E++A +    R  E A     GL         A   DA  GA        
Sbjct: 151 DEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAP 210

Query: 125 -------LASGEPCEDGG----GGPVRSPPGSPGSPRPRRRRL--EPNCAKPRRARTAFT 171
                  +A G P   GG    GG   +P G+  + +P+R+R   +    KPRRARTAFT
Sbjct: 211 GPRENSPVAQGPP---GGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFT 267

Query: 172 YEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQV 231
           YEQLVALENKF+ATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD +A  
Sbjct: 268 YEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPT 327

Query: 232 -GGGAPQPGAAGGGG--GGGSGGSPGPPGTGALHFQ---TFPSYSAANVLFPSAASFPLT 285
            GGG P PGA  G G  GG S  SP PP    L       +P++    ++  +   F L+
Sbjct: 328 GGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGLVCAAQLPF-LS 386

Query: 286 AAAPGSPFAPFLG-PSYLTP-FYAPRL 310
           + A  SPF   LG  +Y  P FYAP L
Sbjct: 387 SPAVLSPFV--LGSQTYGAPAFYAPHL 411


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score =  175 bits (443), Expect = 5e-44
 Identities = 114/223 (51%), Positives = 134/223 (60%), Gaps = 21/223 (9%)

Query: 98  PRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRL- 156
           P  P  R+R          +P  P GA A G        G   +P G+  + +P+R+R  
Sbjct: 38  PEPPSTRQRPPGPRENSPVAPGPPGGAAAPG--------GAGTTPQGTATAAKPKRKRTG 89

Query: 157 -EPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRR 215
            +    KPRRARTAFTYEQLVALENKF+ATRYLSVCERLNLALSLSLTETQVKIWFQNRR
Sbjct: 90  SDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRR 149

Query: 216 TKWKKQNPGADGAAQV-GGGAPQPGAAGGGG--GGGSGGSPGPPGTGALHFQ---TFPSY 269
           TKWKKQNPGAD +A   GGG P PGA  G G  GG S  SP PP    L       +P++
Sbjct: 150 TKWKKQNPGADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAH 209

Query: 270 SAANVLFPSAASFPLTAAAPGSPFAPFLG-PSYLTP-FYAPRL 310
               ++  +   F L++ A  SPF   LG  +Y  P FYAP L
Sbjct: 210 GPGGLVCAAQLPF-LSSPAVLSPFV--LGSQTYGAPAFYAPHL 249


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 88/272 (32%), Positives = 103/272 (37%), Gaps = 77/272 (28%)

Query: 74  AGPGAGQASPLEGSEAE----EEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGE 129
           AG GAGQA     + A     +EE A+    P L   +   L    R P A   ALA  E
Sbjct: 25  AGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSE 84

Query: 130 PCEDGGGG--PVRSPPGSPG---------------------------------------- 147
             +  GG   P+  PPGS G                                        
Sbjct: 85  GVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTP 144

Query: 148 -------SPRPRRRRLEPNCA-----KPRRARTAFTYEQLVALENKFRATRYLSVCERLN 195
                  SP P RR   P C        R+ RT FT  QL+ALE KFR  +YLS+ ER  
Sbjct: 145 WMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAE 204

Query: 196 LALSLSLTETQVKIWFQNRRTKWKKQN----------------PGADGAAQVGGGAPQPG 239
            + SLSLTETQVKIWFQNRR K K+                  P A G +   GG   P 
Sbjct: 205 FSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGG---PA 261

Query: 240 AAGGGGGGGSGGSPGPPGTGALHFQTFPSYSA 271
           A     G    G+ GP    AL       Y+A
Sbjct: 262 AVAAAAGASLYGASGPFQRAALPVAPVGLYTA 293


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 52/106 (49%), Positives = 63/106 (59%), Gaps = 13/106 (12%)

Query: 162 KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 221
           K RR RTAFT +QL+ LE++F+  +YLS  +R  +A SL LTETQVKIWFQNRR KWK+ 
Sbjct: 240 KCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRS 299

Query: 222 NPGADGAAQVGGGAPQPGAAGGGGGGGSGGSP--------GPPGTG 259
               + AAQ           GGGGG G GG+         GPP  G
Sbjct: 300 KKAKEQAAQ-----EAEKQKGGGGGAGKGGAEEPGAEELLGPPAPG 340



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 8/48 (16%)

Query: 236 PQPG--AAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAAS 281
           P+PG   AGGGGGG  GG  GP      H    P  +AA     +AA+
Sbjct: 92  PKPGFLGAGGGGGGTGGGHGGP------HHHAHPGAAAAAAAAAAAAA 133



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 9/53 (16%)

Query: 240 AAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSP 292
           A+G GGGGG GG+ G  GT         S S A+   P+A +  L A +P  P
Sbjct: 38  ASGTGGGGGGGGASG--GTSG-------SCSPASSEPPAAPADRLRAESPSPP 81



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 1/63 (1%)

Query: 222 NPGADGAAQVGGGAPQPGA-AGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAA 280
           +PGA  AA     A   G  A G   GG+ G  G P   AL+      YSAA      A 
Sbjct: 118 HPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAG 177

Query: 281 SFP 283
             P
Sbjct: 178 QHP 180


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 67/177 (37%), Positives = 88/177 (49%), Gaps = 37/177 (20%)

Query: 145 SPGSPRPRRRRLEPNCA-------KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLA 197
           SP +  P +  LEP          K R+ RT ++  QL AL+ +F+ T+YL++ ER  LA
Sbjct: 127 SPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELA 186

Query: 198 LSLSLTETQVKIWFQNRRTKWKK----------QNPGADGA-----------AQVGGGAP 236
            SL LT+TQVKIWFQNRR+K+KK          Q+PGA  +           A    G P
Sbjct: 187 ASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFGVP 246

Query: 237 QPGAAGGG---GGGGSGGSPGPPGTGALHF-QTFPSYSAANVLFPSAASFPLTAAAP 289
           Q  A GGG   GG G+G S   P + A  F   +P Y        S ++  L A AP
Sbjct: 247 QRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGNYPWYHQT-----SGSASHLQATAP 298


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 78/254 (30%), Positives = 100/254 (39%), Gaps = 40/254 (15%)

Query: 41  PAPREARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRR 100
           P P  + K+L    +    + RD    L   D         SP E     EE D+E+ ++
Sbjct: 130 PRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDE--IILEESDSEESKK 187

Query: 101 PRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNC 160
                      PG A +    A A    E  + G   P + P                 C
Sbjct: 188 E------GEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPA----------------C 225

Query: 161 AKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 220
            K ++ RT F+  Q+  LE+ F   RYLS  ER  LA SL LTETQVKIWFQNRR KWK+
Sbjct: 226 RK-KKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKR 284

Query: 221 QNPGADGAAQVGGGAPQ----------PGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYS 270
           Q      AA +   A Q            +A  G    + G+P P     L F     YS
Sbjct: 285 QLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQPLLTFPHPVYYS 344

Query: 271 AANVLFPSAASFPL 284
                 P  +S PL
Sbjct: 345 -----HPVVSSVPL 353


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 88.2 bits (217), Expect = 8e-18
 Identities = 86/266 (32%), Positives = 112/266 (42%), Gaps = 32/266 (12%)

Query: 73  AAGPGAG----QASPLEGSEAEEEEDA--EDPRRPRLRERAARLLPGLARSPDAPAGALA 126
           AAG G G    +   LE  E E+EE+   ED     L + A  LL    R P A  GA+A
Sbjct: 216 AAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVA 275

Query: 127 SGEPC----EDGGGGPVRS----PPGSPGSPRPRRRRLEPNC--------AKPRRARTAF 170
           +        E G   P       P  + G        L             K RR RT F
Sbjct: 276 AAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTF 335

Query: 171 TYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQ 230
           T  QL  LE  F+ T Y  V  R  LA+ L LTE +V++WFQNRR KW+K+         
Sbjct: 336 TSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHP 395

Query: 231 VGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAP- 289
            G   P P +A          SP PP   AL      + +AA   FPS    P +A+ P 
Sbjct: 396 PGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPP 455

Query: 290 -GSP--FAPFLG------PSYLTPFY 306
            G+P   + FLG      P++++P +
Sbjct: 456 SGAPLGLSTFLGAAVFRHPAFISPAF 481



 Score = 31.6 bits (70), Expect = 0.94
 Identities = 46/183 (25%), Positives = 65/183 (35%), Gaps = 24/183 (13%)

Query: 78  AGQASPLEGSEAEEEEDAEDPRRPRLR-ERAARLLPGLARSPDAPAGALASGEPCEDGGG 136
           A Q SP   S   E E    P+  RL      RLL G A +  A A A A+      G  
Sbjct: 63  AVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAGPR 122

Query: 137 GPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNL 196
           G   +PP  P + RP  R      A    A  A  ++ L                 +++ 
Sbjct: 123 G--EAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTL-----------------KISQ 163

Query: 197 ALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPP 256
           A  +S++ ++    ++     +    P  D     GG        G  GG GS  + G  
Sbjct: 164 APQVSISRSKS---YRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAG-G 219

Query: 257 GTG 259
           GTG
Sbjct: 220 GTG 222


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 64/183 (34%), Positives = 75/183 (40%), Gaps = 45/183 (24%)

Query: 162 KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 221
           K RR RT FT  QL  LE  F  T Y  +  R  LAL + LTE +V++WFQNRR K++KQ
Sbjct: 97  KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQ 156

Query: 222 NPGADGAA-----------------------------QVGGGAPQP------GAAGGGGG 246
              A  AA                               GG  P P      GA GGGGG
Sbjct: 157 ERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGGGG 216

Query: 247 G----------GSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPF 296
           G          G GG  G PG G        + +AA     +AA     A  PG  +AP 
Sbjct: 217 GPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAPG 276

Query: 297 LGP 299
            GP
Sbjct: 277 PGP 279



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 6/74 (8%)

Query: 78  AGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGG 137
           A  A+   GS  ++ + + D      +        G   +P+      A+G     GGGG
Sbjct: 162 AAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANG----GGGGG 217

Query: 138 PVRSPPGSPGSPRP 151
           P  SP G+PG+  P
Sbjct: 218 P--SPAGAPGAAGP 229



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 16/81 (19%)

Query: 71  PDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEP 130
           P AAGPG     P +G  A                 AA      A +  A  G  A+G P
Sbjct: 224 PGAAGPGGPGGEPGKGGAA--------------AAAAAAAAAAAAAAAAAAGGLAAAGGP 269

Query: 131 CED--GGGGPVRSPPGSPGSP 149
            +    G GP+ S P S G P
Sbjct: 270 GQGWAPGPGPITSIPDSLGGP 290


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 62/172 (36%), Positives = 83/172 (48%), Gaps = 35/172 (20%)

Query: 112 PGLA-RSP-DAPAGALAS--GEPCEDGGGGPVRSPPG-SPGSPRPRRRR----------- 155
           PGL+ R+P   PAGAL    G+ CE     P   P   +P  P P               
Sbjct: 87  PGLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMR 146

Query: 156 ------LEPNCA--KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQV 207
                 + PN A  +P+R+RTA+T +Q++ LE +F   RYL+   R+ +A +L L+E Q+
Sbjct: 147 KVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQI 206

Query: 208 KIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTG 259
           KIWFQNRR KWKK +             P      GG  G +GG PG P  G
Sbjct: 207 KIWFQNRRMKWKKDHK-----------LPNTKIRSGGAAGSAGGPPGRPNGG 247


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 62/179 (34%), Positives = 76/179 (42%), Gaps = 34/179 (18%)

Query: 134 GGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCER 193
           GGGG  +SPPGS  S               +RARTA+T  QLV LE +F   RYL    R
Sbjct: 174 GGGGGDKSPPGSAAS---------------KRARTAYTSAQLVELEKEFHFNRYLCRPRR 218

Query: 194 LNLALSLSLTETQVKIWFQNRRTKWKKQN-----PGADGAAQVGGGAPQPGAAGGGGGGG 248
           + +A  L+L+E Q+KIWFQNRR K+KK         + G     G  PQP  +  G    
Sbjct: 219 VEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNA 278

Query: 249 ------SGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPSY 301
                 S  SP PP  G  H   +          PS    PL        + P   P Y
Sbjct: 279 LHSMTPSYESPSPPAFGKAHQNAY--------ALPSNYQPPLKGCGAPQKYPPTPAPEY 329



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 5/60 (8%)

Query: 206 QVKIWFQNRR--TKWKKQNPGAD---GAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGA 260
           Q+  W +  R  +K K  +PG     G    GGG    G +GGGGGGG GG   PPG+ A
Sbjct: 128 QIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAA 187


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 87/302 (28%), Positives = 110/302 (36%), Gaps = 38/302 (12%)

Query: 36  LPAVRPAPREARKSLAEVEAGKDASSRDPVRQLE-----TPDAAGPGAGQASPLEGSEAE 90
           LP   PA  +   SLA         S   +  +E     T D    G   A    G+   
Sbjct: 3   LPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGTFPAE--RGARGA 60

Query: 91  EEEDAE---DPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPG 147
           +E D      P  P+  E  +   P  A +P     A     P E G   P    P  P 
Sbjct: 61  KERDRRLGARPACPKAPEEGSEPSPPPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPA 120

Query: 148 SPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQV 207
           +   +    E    K RR RT FT  QL  LE  F  + Y  V  R  LA  ++L E +V
Sbjct: 121 TGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRV 180

Query: 208 KIWFQNRRTKWKKQ------------NPGADGAAQVGGGAPQPGAAGGGGGGGSGG---- 251
           ++WFQNRR KW++Q            +P    +         P  AG G GGG  G    
Sbjct: 181 QVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALP 240

Query: 252 -----SPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTAAAPGSPFAPFLGPSYLTPFY 306
                 P  PG GA   Q+ P +       P A S P +   P  P  PFL    L P  
Sbjct: 241 LESWLGPPLPGGGATALQSLPGFG------PPAQSLPASYTPPPPP-PPFLNSPPLGPGL 293

Query: 307 AP 308
            P
Sbjct: 294 QP 295


>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
          Length = 348

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 73/230 (31%), Positives = 108/230 (46%), Gaps = 31/230 (13%)

Query: 1   MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60
           ++A   GG  A+P H + + +       +KF    LP      + A    A+ E GK   
Sbjct: 104 LMATLPGGFSASPQHQEAAAA-------RKFAPQPLPGGGNFDK-AEALQADAEDGKGFL 155

Query: 61  SRD----PVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLAR 116
           +++         ET  A+  GA +    + S+ E++        P+ +E +  L   +  
Sbjct: 156 AKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDD--------PKGKEESFSLESDVDY 207

Query: 117 SPDAPAGALASGEPCEDGGGGPVRSPP--GSPGSPRPRRRRLEPNCAKPRRARTAFTYEQ 174
           S D      A+ +  ED G     +PP  G+ GS          +  K RR RTAFT EQ
Sbjct: 208 SSDDNLTGQAAHKE-EDPGHALEETPPSSGAAGSTT--------STGKNRRRRTAFTSEQ 258

Query: 175 LVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPG 224
           L+ LE +F   +YLS+ ER  +A +L L+E QVKIWFQNRR KWK+   G
Sbjct: 259 LLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAG 308


>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
          Length = 327

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 55/147 (37%), Positives = 72/147 (48%), Gaps = 39/147 (26%)

Query: 162 KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 221
           KPR+ARTAFT  QL  LE  F   +YLSV +R+ LA SL+LT+TQVK W+QNRRTKWK+Q
Sbjct: 177 KPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQ 236

Query: 222 NP-GADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAA 280
              G +  A+ G                                   +YSA   +FPS  
Sbjct: 237 TAVGLELLAEAG-----------------------------------NYSALQRMFPSPY 261

Query: 281 SFPLTAAA---PGSPFAPFLGPSYLTP 304
            +P +  +   PG+    + GPS   P
Sbjct: 262 FYPQSLVSNLDPGAALYLYRGPSAPPP 288


>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
          Length = 279

 Score = 84.7 bits (208), Expect = 9e-17
 Identities = 49/122 (40%), Positives = 66/122 (54%), Gaps = 9/122 (7%)

Query: 99  RRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEP 158
           R+P +        PG+A++       +      E  GG  + S       P PR++    
Sbjct: 78  RQPTVISHLVPATPGIAQA--LSCHQVTEAVSAEAPGGEALASSESETEQPTPRQK---- 131

Query: 159 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 218
              KPRR+RT FT  QL+ LE KF+  +YLS  +RL+LA SL LT+ QVK W+QNRR KW
Sbjct: 132 ---KPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKW 188

Query: 219 KK 220
           KK
Sbjct: 189 KK 190


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 66/212 (31%), Positives = 103/212 (48%), Gaps = 19/212 (8%)

Query: 26  LDPQKFTRAALPAVRPAPREARKSLAEVEAGKDASS----RDPVRQLETPDAAGPGAGQA 81
           L P    +  LP  +P P   ++  +   A + ++S    +D +   +   A  P +   
Sbjct: 105 LQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSV 164

Query: 82  SPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRS 141
           S    +  +E     +  RP+L +  ++    L +  D+ +     G   E+G     R 
Sbjct: 165 SSPHHTPKQESNAVHESFRPKLEQEDSKTK--LDKREDSQSDIKCHGTK-EEGD----RE 217

Query: 142 PPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLS 201
              S  SP  R +       KPR+ARTAF+  QL  LE  F   +YLSV +R++LA +L+
Sbjct: 218 ITSSRESPPVRAK-------KPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALN 270

Query: 202 LTETQVKIWFQNRRTKWKKQNP-GADGAAQVG 232
           LT+TQVK W+QNRRTKWK+Q   G +  A+ G
Sbjct: 271 LTDTQVKTWYQNRRTKWKRQTAVGLELLAEAG 302


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 93/312 (29%), Positives = 116/312 (37%), Gaps = 105/312 (33%)

Query: 73  AAGPGAGQASPLEGSEAEEEEDAEDP--------RRPRLRERA---------------AR 109
           A   GAG+A+  +GS  +EEED +DP        RR RL+ R                A 
Sbjct: 27  AEAKGAGRATQGDGSREDEEEDDDDPEDEDAEQARRRRLQRRRQLLAGTGPGGEARARAL 86

Query: 110 LLPGLA----RSPDAPA-------GALASGEPCEDGGGGPVRSP---------------- 142
           L PG      R P  P        G  A   P   GG G   SP                
Sbjct: 87  LGPGALGLGPRPPPGPGPPFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGR 146

Query: 143 -----PGSPGSPRPRRRRLEPNCAKP-------------------------------RRA 166
                P  PG    +R   E     P                               ++ 
Sbjct: 147 AEGAWPRGPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGVGGGRKKKT 206

Query: 167 RTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 226
           RT F+  Q+  LE+ F   RYLS  ER  LA SL LTETQVKIWFQNRR KWK+Q     
Sbjct: 207 RTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQL---- 262

Query: 227 GAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTA 286
            AA++   +  P            G+        L+ ++ P+ +AA    P+   FPL  
Sbjct: 263 -AAELEAASLSP-----------PGAQRLVRVPVLYHESPPAAAAAGP--PATLPFPLAP 308

Query: 287 AAPGSPFAPFLG 298
           AAP  P  P LG
Sbjct: 309 AAPAPP-PPLLG 319


>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
          Length = 363

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 68/194 (35%), Positives = 86/194 (44%), Gaps = 32/194 (16%)

Query: 33  RAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEE 92
           + A P   P P  +    +    GK  SS +   +LE   +AG  AG     EGS  + E
Sbjct: 159 KVAEPPPPPPPHFSETFPSLPAEGKVYSSDE--EKLEA--SAGDPAGSEQEEEGSGGDSE 214

Query: 93  EDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDG--GGGPVRSPPGSPGSPR 150
           +D                  G   S     GAL   +P   G  G G     P + G   
Sbjct: 215 DD------------------GFLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPVTAGVTA 256

Query: 151 PRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIW 210
           P          K RR RTAFT EQL+ LE +F   +YLS+ ER  +A +L L+E QVKIW
Sbjct: 257 PG--------GKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIW 308

Query: 211 FQNRRTKWKKQNPG 224
           FQNRR KWK+   G
Sbjct: 309 FQNRRAKWKRIKAG 322



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/80 (37%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 230 QVGGGAPQPGAAGGGGGGGSGGS--------PGPPGTGALHFQTFPSYSAAN--VLFPSA 279
           Q  GG   PG  GGGGGGG G +        P PP +G L +  +P +      VL  + 
Sbjct: 2   QRAGGGSAPGGNGGGGGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQAL 61

Query: 280 ASFPLTAAAPG-SPFAPFLG 298
           A  PL A  P  +P A F G
Sbjct: 62  APAPLPAGLPPLAPLASFAG 81


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 75/243 (30%), Positives = 100/243 (41%), Gaps = 37/243 (15%)

Query: 13  PSHHKISFSVLDILD--PQKFTRAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLET 70
           P  H++S + L  L   P +      P + P P +A        A        P  Q   
Sbjct: 62  PKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQA--------APPAPQPPQPAPQPPA 113

Query: 71  PD-AAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRER--AARLLPGLARSPD---APAGA 124
           P  AA P    ASP + + +     A   + P L     A ++ P +  S         +
Sbjct: 114 PTPAAPPPPSSASPPQNA-SNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSS 172

Query: 125 LASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRA 184
            +SGE C        +SPPG   S               +RARTA+T  QLV LE +F  
Sbjct: 173 SSSGESCAGD-----KSPPGQASS---------------KRARTAYTSAQLVELEKEFHF 212

Query: 185 TRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGG 244
            RYL    R+ +A  L+LTE Q+KIWFQNRR K+KK   G       GG +P       G
Sbjct: 213 NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 272

Query: 245 GGG 247
            GG
Sbjct: 273 AGG 275


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 75/243 (30%), Positives = 100/243 (41%), Gaps = 37/243 (15%)

Query: 13  PSHHKISFSVLDILD--PQKFTRAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLET 70
           P  H++S + L  L   P +      P + P P +A        A        P  Q   
Sbjct: 62  PKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQA--------APPAPQPPQPAPQPPA 113

Query: 71  PD-AAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRER--AARLLPGLARSPD---APAGA 124
           P  AA P    ASP + + +     A   + P L     A ++ P +  S         +
Sbjct: 114 PTPAAPPPPSSASPPQNA-SNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSS 172

Query: 125 LASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRA 184
            +SGE C        +SPPG   S               +RARTA+T  QLV LE +F  
Sbjct: 173 SSSGESCAGD-----KSPPGQASS---------------KRARTAYTSAQLVELEKEFHF 212

Query: 185 TRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGG 244
            RYL    R+ +A  L+LTE Q+KIWFQNRR K+KK   G       GG +P       G
Sbjct: 213 NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 272

Query: 245 GGG 247
            GG
Sbjct: 273 AGG 275


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 73/254 (28%), Positives = 99/254 (38%), Gaps = 25/254 (9%)

Query: 28  PQKFTRAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGS 87
           P+     A PA    P       A     +  +S     Q E P A   G     P  G 
Sbjct: 76  PRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKG-----PAHGL 130

Query: 88  EAEE--EEDAEDPRRPRLRERAA-RLLPGLARSPDAPAGALASGEPCEDGGGGPV----R 140
            A    +     P +PR    AA R       +P  PAG  A   P       P+    +
Sbjct: 131 HASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLADKSPLGLKGK 190

Query: 141 SPPGSPGSPRPRRRRLEP--NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLAL 198
            P   P   +     + P  N  +P+R+RTA+T +Q++ LE +F   RYL+   R+ +A 
Sbjct: 191 EPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAH 250

Query: 199 SLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGT 258
           +L L+E QVKIWFQNRR KWKK +             P            S G PG   T
Sbjct: 251 TLCLSERQVKIWFQNRRMKWKKDHK-----------LPNTKMRSSNSASASAGPPGKAQT 299

Query: 259 GALHFQTFPSYSAA 272
            + H    P  S +
Sbjct: 300 QSPHLHPHPHPSTS 313


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 66/189 (34%), Positives = 86/189 (45%), Gaps = 35/189 (18%)

Query: 45  EARKSLAEVEAGKDASSRDPVRQLE-TPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRL 103
           +AR +     AG   S   PV +L  + D     AG+      S++E        R PR 
Sbjct: 109 DARGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGR------SDSEMSASVSGDRSPRT 162

Query: 104 RERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPG------SPGSPRPRRRRLE 157
            +               P GA  S   C   GGG    P G       P +P+PR++R  
Sbjct: 163 EDDGV-----------GPRGAHVSAL-CSGAGGGGGSGPAGVAEEEEEPAAPKPRKKR-- 208

Query: 158 PNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTK 217
                   +R AF++ Q+  LE +F   RYLS  ER +LA SL LTETQVKIWFQNRR K
Sbjct: 209 --------SRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYK 260

Query: 218 WKKQNPGAD 226
            K++   AD
Sbjct: 261 TKRRQMAAD 269


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 81.6 bits (200), Expect = 8e-16
 Identities = 56/153 (36%), Positives = 74/153 (48%), Gaps = 24/153 (15%)

Query: 149 PRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVK 208
           P+PR RR         + R  F+  Q+  LE +F+  RYLS  ER +LA SL LT TQVK
Sbjct: 143 PKPRSRR---------KPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVK 193

Query: 209 IWFQNRRTKWKKQNPGADGAAQVGGGAPQP-------------GAAGGGGGGGSGGSPGP 255
           IWFQNRR K K+Q    D + ++G  AP P             G         + G+P  
Sbjct: 194 IWFQNRRYKCKRQR--QDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYS 251

Query: 256 PGTGALHFQTFPSYSAANVLFPSAASFPLTAAA 288
            G  A  + +FP+Y   N    +AA+    AAA
Sbjct: 252 VGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAA 284


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 75/235 (31%), Positives = 101/235 (42%), Gaps = 30/235 (12%)

Query: 80  QASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPV 139
           Q SP + S  E    A+DP    L       LP     P  PAG      P  +G    V
Sbjct: 59  QGSPPDISPYEVPPLADDPAVAHLHHH----LPAQLALPHPPAG------PFPEGAEPGV 108

Query: 140 RSPPGSPGSPRPRRRRLEPNC-----------AKP---RRARTAFTYEQLVALENKFRAT 185
              P     P P  +  + +            A+P   +R RTA+T  QL+ LE +F   
Sbjct: 109 LEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFN 168

Query: 186 RYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK-QNPGADGAAQVGGGA---PQPGAA 241
           +Y+S   R+ LA+ L+LTE  +KIWFQNRR KWKK ++    G   VGGG    P+   A
Sbjct: 169 KYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCA 228

Query: 242 GGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPL-TAAAPGSPFAP 295
              G       P PP  GA+     P  +    L P  ++ P  ++ AP  P  P
Sbjct: 229 VTSGEELLALPPPPPPGGAVP-PAAPVAAREGRLPPGLSASPQPSSVAPRRPQEP 282


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 57/159 (35%), Positives = 77/159 (48%), Gaps = 20/159 (12%)

Query: 118 PDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRP---------RRRRLEPNC--AKPRRA 166
           P   +GA AS  P       P    P S  S +P             + PN    +P+R+
Sbjct: 100 PAPLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRS 159

Query: 167 RTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 226
           RTA+T +Q++ LE +F   RYL+   R+ +A SL L+E Q+KIWFQNRR KWKK +   +
Sbjct: 160 RTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPN 219

Query: 227 GAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQT 265
              +    AP  GAA       S  S   PGT   H Q+
Sbjct: 220 TKVR---SAPPAGAA------PSTLSAATPGTSEDHSQS 249


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 57/159 (35%), Positives = 77/159 (48%), Gaps = 20/159 (12%)

Query: 118 PDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRP---------RRRRLEPNC--AKPRRA 166
           P   +GA AS  P       P    P S  S +P             + PN    +P+R+
Sbjct: 100 PAPLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRS 159

Query: 167 RTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 226
           RTA+T +Q++ LE +F   RYL+   R+ +A SL L+E Q+KIWFQNRR KWKK +   +
Sbjct: 160 RTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPN 219

Query: 227 GAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQT 265
              +    AP  GAA       S  S   PGT   H Q+
Sbjct: 220 TKVR---SAPPAGAA------PSTLSAATPGTSEDHSQS 249


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,615,638
Number of Sequences: 37866
Number of extensions: 1079255
Number of successful extensions: 29289
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 777
Number of HSP's successfully gapped in prelim test: 751
Number of HSP's that attempted gapping in prelim test: 10314
Number of HSP's gapped (non-prelim): 14347
length of query: 310
length of database: 18,247,518
effective HSP length: 102
effective length of query: 208
effective length of database: 14,385,186
effective search space: 2992118688
effective search space used: 2992118688
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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