Search of human proteins with 226371718

Search of human proteins with 226371718

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226371718 poly (ADP-ribose) polymerase family, member 9
isoform c [Homo sapiens]
         (710 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226371718 poly (ADP-ribose) polymerase family, member 9 isofo...  1418   0.0  
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo...  1382   0.0  
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo...  1382   0.0  
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo...  1382   0.0  
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo...  1364   0.0  
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo...  1364   0.0  
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom...   224   2e-58
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof...   124   2e-28
gi|22749259 poly (ADP-ribose) polymerase family, member 15 isofo...    85   2e-16
gi|13569840 MACRO domain containing 1 [Homo sapiens]                   76   1e-13
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]        67   4e-11
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]      60   5e-09
gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]       57   8e-08
gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]      57   8e-08
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]      57   8e-08
gi|8923920 H2A histone family, member Y2 [Homo sapiens]                51   3e-06
gi|207450721 ganglioside induced differentiation associated prot...    48   4e-05
gi|8923143 ganglioside induced differentiation associated protei...    48   4e-05
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   40   0.010
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]    37   0.048
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    35   0.18 
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       35   0.18 
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]          34   0.54 
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...    33   0.70 
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...    33   0.70 
gi|4505257 moesin [Homo sapiens]                                       33   0.70 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    33   0.70 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    33   0.70 
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    33   1.2  
gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Hom...    33   1.2  

>gi|226371718 poly (ADP-ribose) polymerase family, member 9 isoform
           c [Homo sapiens]
          Length = 710

 Score = 1418 bits (3671), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60
           MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL
Sbjct: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60

Query: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120
           VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK
Sbjct: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120

Query: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
           AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180

Query: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240
           AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI
Sbjct: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240

Query: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300
           HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV
Sbjct: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300

Query: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360
           NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL
Sbjct: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360

Query: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420
           WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK
Sbjct: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420

Query: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480
           DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP
Sbjct: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480

Query: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540
           AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE
Sbjct: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540

Query: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600
           IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD
Sbjct: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600

Query: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660
           EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH
Sbjct: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660

Query: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCGRCQCLIIGATLWNLVS 710
           RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCGRCQCLIIGATLWNLVS
Sbjct: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCGRCQCLIIGATLWNLVS 710


>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 1382 bits (3577), Expect = 0.0
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60
           MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL
Sbjct: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60

Query: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120
           VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK
Sbjct: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120

Query: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
           AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180

Query: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240
           AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI
Sbjct: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240

Query: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300
           HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV
Sbjct: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300

Query: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360
           NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL
Sbjct: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360

Query: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420
           WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK
Sbjct: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420

Query: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480
           DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP
Sbjct: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480

Query: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540
           AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE
Sbjct: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540

Query: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600
           IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD
Sbjct: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600

Query: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660
           EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH
Sbjct: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660

Query: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC 693
           RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC
Sbjct: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC 693


>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 1382 bits (3577), Expect = 0.0
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60
           MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL
Sbjct: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60

Query: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120
           VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK
Sbjct: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120

Query: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
           AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180

Query: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240
           AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI
Sbjct: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240

Query: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300
           HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV
Sbjct: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300

Query: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360
           NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL
Sbjct: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360

Query: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420
           WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK
Sbjct: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420

Query: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480
           DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP
Sbjct: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480

Query: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540
           AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE
Sbjct: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540

Query: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600
           IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD
Sbjct: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600

Query: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660
           EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH
Sbjct: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660

Query: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC 693
           RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC
Sbjct: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC 693


>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 1382 bits (3577), Expect = 0.0
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60
           MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL
Sbjct: 1   MDFSMVAGAAAYNEKSETGALGENYSWQIPINHNDFKILKNNERQLCEVLQNKFGCISTL 60

Query: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120
           VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK
Sbjct: 61  VSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVK 120

Query: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
           AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180

Query: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240
           AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI
Sbjct: 181 AIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEI 240

Query: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300
           HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV
Sbjct: 241 HLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIV 300

Query: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360
           NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL
Sbjct: 301 NSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL 360

Query: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420
           WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK
Sbjct: 361 WHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAK 420

Query: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480
           DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP
Sbjct: 421 DHVKHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSP 480

Query: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540
           AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE
Sbjct: 481 AINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITE 540

Query: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600
           IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD
Sbjct: 541 IISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQD 600

Query: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660
           EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH
Sbjct: 601 EMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLH 660

Query: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC 693
           RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC
Sbjct: 661 RQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPC 693


>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 1364 bits (3531), Expect = 0.0
 Identities = 693/728 (95%), Positives = 693/728 (95%), Gaps = 35/728 (4%)

Query: 1   MDFSMVAGAAAYNEKS-----------------------------------ETGALGENY 25
           MDFSMVAGAAAYNEKS                                   ETGALGENY
Sbjct: 1   MDFSMVAGAAAYNEKSGRITSLSLLFQKVFAQIFPQWRKGNTEECLPYKCSETGALGENY 60

Query: 26  SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL 85
           SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL
Sbjct: 61  SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL 120

Query: 86  SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI 145
           SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI
Sbjct: 121 SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI 180

Query: 146 AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS 205
           AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS
Sbjct: 181 AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS 240

Query: 206 SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE 265
           SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE
Sbjct: 241 SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE 300

Query: 266 LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM 325
           LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM
Sbjct: 301 LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM 360

Query: 326 KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ 385
           KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ
Sbjct: 361 KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ 420

Query: 386 NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS 445
           NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS
Sbjct: 421 NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS 480

Query: 446 SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL 505
           SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL
Sbjct: 481 SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL 540

Query: 506 QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI 565
           QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI
Sbjct: 541 QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI 600

Query: 566 EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ 625
           EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ
Sbjct: 601 EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ 660

Query: 626 FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF 685
           FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF
Sbjct: 661 FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF 720

Query: 686 QRMYSTPC 693
           QRMYSTPC
Sbjct: 721 QRMYSTPC 728


>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 1364 bits (3531), Expect = 0.0
 Identities = 693/728 (95%), Positives = 693/728 (95%), Gaps = 35/728 (4%)

Query: 1   MDFSMVAGAAAYNEKS-----------------------------------ETGALGENY 25
           MDFSMVAGAAAYNEKS                                   ETGALGENY
Sbjct: 1   MDFSMVAGAAAYNEKSGRITSLSLLFQKVFAQIFPQWRKGNTEECLPYKCSETGALGENY 60

Query: 26  SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL 85
           SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL
Sbjct: 61  SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL 120

Query: 86  SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI 145
           SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI
Sbjct: 121 SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI 180

Query: 146 AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS 205
           AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS
Sbjct: 181 AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS 240

Query: 206 SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE 265
           SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE
Sbjct: 241 SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE 300

Query: 266 LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM 325
           LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM
Sbjct: 301 LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM 360

Query: 326 KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ 385
           KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ
Sbjct: 361 KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ 420

Query: 386 NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS 445
           NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS
Sbjct: 421 NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS 480

Query: 446 SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL 505
           SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL
Sbjct: 481 SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL 540

Query: 506 QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI 565
           QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI
Sbjct: 541 QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI 600

Query: 566 EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ 625
           EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ
Sbjct: 601 EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ 660

Query: 626 FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF 685
           FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF
Sbjct: 661 FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF 720

Query: 686 QRMYSTPC 693
           QRMYSTPC
Sbjct: 721 QRMYSTPC 728


>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
            sapiens]
          Length = 1801

 Score =  224 bits (572), Expect = 2e-58
 Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)

Query: 50   LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 105
            ++  FGC   L     ++EG S + Q    R +L P + L V + DL    VD VVNA+N
Sbjct: 765  IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824

Query: 106  EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 165
            EDL H GGLA AL KA G E+Q +  Q V R G++  G   ++ AG+LP   +IHAVGPR
Sbjct: 825  EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884

Query: 166  WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 225
            W  ++   C   L+RA+   L+  + +    +++AIPA+SSG+F FPL  C +TIV  I+
Sbjct: 885  WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942

Query: 226  VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 269
             + Q K     LKEI+LV   + TV AF  A + +  K+ L                G+ 
Sbjct: 943  ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001

Query: 270  TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 327
            +    + +    L + +V+  ++    DV+VNSV P D+ +  GP++KS+L++AG E++ 
Sbjct: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060

Query: 328  EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 383
            E              VL T  +NL C+Y+ HV+   W +      +I++  ++EC+E   
Sbjct: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120

Query: 384  EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 442
              ++ SI+FPA+GTGN+   K   AE++  EV  F +K+ +K    V F++ P+D E  +
Sbjct: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180

Query: 443  AFSSEMAKRS 452
            AFS E A+R+
Sbjct: 1181 AFSDEFARRA 1190



 Score =  145 bits (367), Expect = 1e-34
 Identities = 141/553 (25%), Positives = 260/553 (47%), Gaps = 54/553 (9%)

Query: 63   PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 120
            P   G  K+      +++P  +++ + K+ +     D VVN+   DL L  G L+ +L++
Sbjct: 993  PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052

Query: 121  AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
              G E+QEE    V +   VS G +  T +  L C+ ++H V P W    + G T  L+ 
Sbjct: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107

Query: 181  AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 239
                I   + I ++  +K++A PA+ +G   FP N+  + I+  +      K  +  L+E
Sbjct: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166

Query: 240  IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 281
            +H +   ++   + AF      +A    +  K    ++T   +            M + +
Sbjct: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226

Query: 282  LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 340
            +  Q+  G I  + ADVIVNS  N  ++  G V+K+IL+ AG  ++ E      +  QR 
Sbjct: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282

Query: 341  QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 400
               ++T G  L CK I HV+  ++      +K ++   L++C ++N +SI  PA+GTGN 
Sbjct: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336

Query: 401  EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 449
            +   +  AE + D +  F  K   +    VK VIF P  L+++ A          SS+ +
Sbjct: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396

Query: 450  KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL-QNH 508
              SK+ S   +S     ++       +  S    + G NV  +  A +W+Q ++   Q  
Sbjct: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456

Query: 509  HIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNIEDM 568
            +  E+  I     KE+  L++LQK  +++I+  +   R  +++ G   D+++    IE M
Sbjct: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINIS--LDHKRPLIKVLGISRDVMQARDEIEAM 1514

Query: 569  LCKVQEEMARKKE 581
            + +V+  +A+++E
Sbjct: 1515 IKRVR--LAKEQE 1525


>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
           1 [Homo sapiens]
          Length = 678

 Score =  124 bits (312), Expect = 2e-28
 Identities = 118/404 (29%), Positives = 181/404 (44%), Gaps = 50/404 (12%)

Query: 83  IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 141
           + L +   D+     D +VN+   +L  GGG L+ A ++  G  +Q+E      R  +  
Sbjct: 89  LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147

Query: 142 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 196
            G I +T    L CK ++HAV P W       W       K     V +L++        
Sbjct: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199

Query: 197 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 253
            ++  P + +G  QFP  +  K I+ E    S   +P+ S L+E+H +  +N+D    AF
Sbjct: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259

Query: 254 KAASEF--------------ILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQT 295
               EF              + G ++  +G  + P F A  M +  +T Q+  G I  + 
Sbjct: 260 --LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQ 317

Query: 296 ADVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKY 355
            DVIVNS          V+++IL+ AG  ++SE  A  A Q  R    ++T G  L CK 
Sbjct: 318 VDVIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKI 374

Query: 356 IYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEV 415
           I HV      P  + ++  +   LE+C ++  TS+S PA+GTGN      T A+ + D +
Sbjct: 375 IIHV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAI 428

Query: 416 LTFAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 458
           + F+  H    L TVK VIF    E+   F   M KR    SLN
Sbjct: 429 VDFSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470


>gi|22749259 poly (ADP-ribose) polymerase family, member 15 isoform
           2 [Homo sapiens]
          Length = 444

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 67/196 (34%), Positives = 96/196 (48%), Gaps = 14/196 (7%)

Query: 266 LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGV 323
           +G  + P F A  M +  +T Q+  G I  +  DVIVNS          V+++IL+ AG 
Sbjct: 52  VGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQ 111

Query: 324 EMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCI 383
            ++SE  A  A Q  R    ++T G  L CK I HV      P  + ++  +   LE+C 
Sbjct: 112 AVESE-CAVLAAQPHRD--FIITPGGCLKCKIIIHV------PGGKDVRKTVTSVLEECE 162

Query: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYK 442
           ++  TS+S PA+GTGN      T A+ + D ++ F+  H    L TVK VIF    E+  
Sbjct: 163 QRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQP--ELLN 220

Query: 443 AFSSEMAKRSKMLSLN 458
            F   M KR    SLN
Sbjct: 221 IFYDSMKKRDLSASLN 236



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 17/125 (13%)

Query: 83  IELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSA 142
           I   V   D+ T  VD +VN+         G++ A+++  G  ++ E     A+  +   
Sbjct: 70  ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR--- 126

Query: 143 GEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIP 202
            +  +T  G L CK IIH  G +            +++ + S+L     +     +V++P
Sbjct: 127 -DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEEC--EQRKYTSVSLP 172

Query: 203 ALSSG 207
           A+ +G
Sbjct: 173 AIGTG 177


>gi|13569840 MACRO domain containing 1 [Homo sapiens]
          Length = 325

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 44/146 (30%), Positives = 78/146 (53%), Gaps = 6/146 (4%)

Query: 84  ELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAG 143
           ++S+ + D+T   VDA+VNAAN  LL GGG+   + +A G  + +E +   +       G
Sbjct: 153 KISLLRSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQS----CKTG 208

Query: 144 EIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPA 203
           +  +TG  RLP K +IH VGP            +L+   +S L+ ++     +++VA P 
Sbjct: 209 KAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLL--EHRLRSVAFPC 266

Query: 204 LSSGIFQFPLNLCTKTIVETIRVSLQ 229
           +S+G+F +P     + ++ T+R  L+
Sbjct: 267 ISTGVFGYPCEAAAEIVLATLREWLE 292



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 9/169 (5%)

Query: 281 NLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 340
           N  + +++  I     D IVN+ N   +  G V   I + AG  +  E    +  Q  ++
Sbjct: 151 NEKISLLRSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDE---CRTLQSCKT 207

Query: 341 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHA-MKEC----LEKCIEQNITSISFPAL 395
               +T G+ L  KY+ H +    + +P   + A ++ C    L+  +E  + S++FP +
Sbjct: 208 GKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCI 267

Query: 396 GTGNMEIKKETAAEILFDEVLTFAKDHV-KHQLTVKFVIFPTDLEIYKA 443
            TG      E AAEI+   +  + + H  K    +  V    D +IY++
Sbjct: 268 STGVFGYPCEAAAEIVLATLREWLEQHKDKVDRLIICVFLEKDEDIYRS 316


>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
          Length = 425

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 50/160 (31%), Positives = 75/160 (46%), Gaps = 8/160 (5%)

Query: 66  EGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFE 125
           E N++     +K LT ++  S+++ D+T   VDA+VNAAN  LL GGG+   + +A G  
Sbjct: 55  EENTQETSQVKKSLTEKV--SLYRGDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPC 112

Query: 126 IQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSI 185
           +  E +           G   +T    LP K +IH VGP             L     S 
Sbjct: 113 LLAECRNL----NGCDTGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYKSS 168

Query: 186 LNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 225
           L  V  K  +I++VA P +S+GI+ FP        + TI+
Sbjct: 169 LKLV--KENNIRSVAFPCISTGIYGFPNEPAAVIALNTIK 206



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 63/245 (25%), Positives = 103/245 (42%), Gaps = 23/245 (9%)

Query: 258 EFILGKSELGQETTPSFNAMVVNNLT--LQIVQGHIEWQTADVIVNSVNPHDITVGPVAK 315
           E + GK +  +E T    + V  +LT  + + +G I     D IVN+ N   +  G V  
Sbjct: 45  EEMKGKGQNDEENTQE-TSQVKKSLTEKVSLYRGDITLLEVDAIVNAANASLLGGGGVDG 103

Query: 316 SILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLW-----HSEFPKPQI 370
            I + AG  + +E           ++   +T G++L  KY+ H +      H      + 
Sbjct: 104 CIHRAAGPCLLAECRNLNGCDTGHAK---ITCGYDLPAKYVIHTVGPIARGHINGSHKED 160

Query: 371 LKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTV 429
           L +  K  L+   E NI S++FP + TG      E AA I  + +  + AK+H +    +
Sbjct: 161 LANCYKSSLKLVKENNIRSVAFPCISTGIYGFPNEPAAVIALNTIKEWLAKNHHEVDRII 220

Query: 430 KFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNV 489
             V    D +IYK    +M +   +   N        +E+  ENG E +         +V
Sbjct: 221 FCVFLEVDFKIYK---KKMNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQ--------SV 269

Query: 490 EEMYE 494
           EEM E
Sbjct: 270 EEMEE 274


>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
          Length = 369

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 6/170 (3%)

Query: 84  ELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAG 143
           +L V + D+ +   DAVV+  N D   GG +   L K GG E  E   +   + G +   
Sbjct: 196 KLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVA 255

Query: 144 EIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPA 203
             AV+    LP K +IH   P    W    C   L++ + + L   +  +  +K++A P+
Sbjct: 256 GAAVSAGHGLPAKFVIHCNSP---VWGADKCEELLEKTVKNCL--ALADDKKLKSIAFPS 310

Query: 204 LSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAF 253
           + SG   FP     + I++ I  S     M S++K ++ V  +  ++  +
Sbjct: 311 IGSGRNGFPKQTAAQLILKAIS-SYFVSTMSSSIKTVYFVLFDSESIGIY 359



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 8/172 (4%)

Query: 284 LQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQL- 342
           LQ+VQ  I    +D +V+  N      G V  ++ ++ G E     L  + K        
Sbjct: 197 LQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAG 256

Query: 343 VLVTKGFNLFCKYIYHV---LWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGN 399
             V+ G  L  K++ H    +W ++  + ++L+  +K CL    ++ + SI+FP++G+G 
Sbjct: 257 AAVSAGHGLPAKFVIHCNSPVWGADKCE-ELLEKTVKNCLALADDKKLKSIAFPSIGSGR 315

Query: 400 MEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAK 450
               K+TAA+++   + ++    +   + TV FV+F  D E    +  EMAK
Sbjct: 316 NGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 365


>gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]
          Length = 371

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 46/186 (24%), Positives = 84/186 (45%), Gaps = 10/186 (5%)

Query: 68  NSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQ 127
           ++KSL + +K+     E+S    +L    V+A++N  N D+     L   L K GG E  
Sbjct: 186 STKSLFLGQKLNLIHSEIS----NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFV 241

Query: 128 EESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILN 187
           E   +   + G +     AV+    LP K +IH   P    W    C   L++ + + L 
Sbjct: 242 EAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSP---VWGADKCEELLEKTVKNCL- 297

Query: 188 YVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNED 247
             +  +  +K++A P++ SG   FP     + I++ I  S     M S++K ++ V  + 
Sbjct: 298 -ALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAIS-SYFVSTMSSSIKTVYFVLFDS 355

Query: 248 PTVAAF 253
            ++  +
Sbjct: 356 ESIGIY 361



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 297 DVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQL-VLVTKGFNLFCKY 355
           + I+N  N        +  ++ ++ G E     L  + K          V+ G  L  K+
Sbjct: 212 EAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKF 271

Query: 356 IYHV---LWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILF 412
           + H    +W ++  + ++L+  +K CL    ++ + SI+FP++G+G     K+TAA+++ 
Sbjct: 272 VIHCNSPVWGADKCE-ELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLIL 330

Query: 413 DEVLTFAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAK 450
             + ++    +   + TV FV+F  D E    +  EMAK
Sbjct: 331 KAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 367


>gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]
          Length = 371

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 46/186 (24%), Positives = 84/186 (45%), Gaps = 10/186 (5%)

Query: 68  NSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQ 127
           ++KSL + +K+     E+S    +L    V+A++N  N D+     L   L K GG E  
Sbjct: 186 STKSLFLGQKLNLIHSEIS----NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFV 241

Query: 128 EESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILN 187
           E   +   + G +     AV+    LP K +IH   P    W    C   L++ + + L 
Sbjct: 242 EAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSP---VWGADKCEELLEKTVKNCL- 297

Query: 188 YVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNED 247
             +  +  +K++A P++ SG   FP     + I++ I  S     M S++K ++ V  + 
Sbjct: 298 -ALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAIS-SYFVSTMSSSIKTVYFVLFDS 355

Query: 248 PTVAAF 253
            ++  +
Sbjct: 356 ESIGIY 361



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 297 DVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQL-VLVTKGFNLFCKY 355
           + I+N  N        +  ++ ++ G E     L  + K          V+ G  L  K+
Sbjct: 212 EAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKF 271

Query: 356 IYHV---LWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILF 412
           + H    +W ++  + ++L+  +K CL    ++ + SI+FP++G+G     K+TAA+++ 
Sbjct: 272 VIHCNSPVWGADKCE-ELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLIL 330

Query: 413 DEVLTFAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAK 450
             + ++    +   + TV FV+F  D E    +  EMAK
Sbjct: 331 KAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 367


>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
          Length = 372

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 46/186 (24%), Positives = 84/186 (45%), Gaps = 10/186 (5%)

Query: 68  NSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQ 127
           ++KSL + +K+     E+S    +L    V+A++N  N D+     L   L K GG E  
Sbjct: 187 STKSLFLGQKLNLIHSEIS----NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFV 242

Query: 128 EESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILN 187
           E   +   + G +     AV+    LP K +IH   P    W    C   L++ + + L 
Sbjct: 243 EAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSP---VWGADKCEELLEKTVKNCL- 298

Query: 188 YVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNED 247
             +  +  +K++A P++ SG   FP     + I++ I  S     M S++K ++ V  + 
Sbjct: 299 -ALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAIS-SYFVSTMSSSIKTVYFVLFDS 356

Query: 248 PTVAAF 253
            ++  +
Sbjct: 357 ESIGIY 362



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 8/159 (5%)

Query: 297 DVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQL-VLVTKGFNLFCKY 355
           + I+N  N        +  ++ ++ G E     L  + K          V+ G  L  K+
Sbjct: 213 EAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKF 272

Query: 356 IYHV---LWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILF 412
           + H    +W ++  + ++L+  +K CL    ++ + SI+FP++G+G     K+TAA+++ 
Sbjct: 273 VIHCNSPVWGADKCE-ELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLIL 331

Query: 413 DEVLTFAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAK 450
             + ++    +   + TV FV+F  D E    +  EMAK
Sbjct: 332 KAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 368


>gi|8923920 H2A histone family, member Y2 [Homo sapiens]
          Length = 372

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 43/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%)

Query: 68  NSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQ 127
           +SKSL + +K+   + ++S     + +  V+ +V+    ++     +  AL KAGG E  
Sbjct: 187 SSKSLVLGQKLSLTQSDIS----HIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFL 242

Query: 128 EESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILN 187
           E  K+     G +   E AV+ +  L  K +IH   P   +W    C  +L+  I + L+
Sbjct: 243 ETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIP---QWGSDKCEEQLEETIKNCLS 299

Query: 188 YVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNED 247
               ++  +K+VA P   SG   FP     +  ++ I          S+LK ++ +  + 
Sbjct: 300 AA--EDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDS-SASSLKNVYFLLFDS 356

Query: 248 PTVAAF 253
            ++  +
Sbjct: 357 ESIGIY 362



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 58/236 (24%), Positives = 101/236 (42%), Gaps = 32/236 (13%)

Query: 225 RVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSELGQETTPSFNAMVVNNLTL 284
           R S + KP  S+ +     ++ED     F   S   L    LGQ+   S     ++++  
Sbjct: 155 RTSKKSKPKDSDKEGTSNSTSEDGPGDGFTILSSKSL---VLGQKL--SLTQSDISHIGS 209

Query: 285 QIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVL 344
             V+G +   TA++ +            + K++ +  G     EFL T  K+ ++SQ  L
Sbjct: 210 MRVEGIVHPTTAEIDLKE---------DIGKALEKAGG----KEFLET-VKELRKSQGPL 255

Query: 345 ------VTKGFNLFCKYIYHV---LWHSEFPKPQILKHAMKECLEKCIEQNITSISFPAL 395
                 V++   L  K++ H     W S+  + Q L+  +K CL    ++ + S++FP  
Sbjct: 256 EVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQ-LEETIKNCLSAAEDKKLKSVAFPPF 314

Query: 396 GTGNMEIKKETAAEILFDEVLTFAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAK 450
            +G     K+TAA++    +     D     L  V F++F  D E    +  EMAK
Sbjct: 315 PSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLF--DSESIGIYVQEMAK 368


>gi|207450721 ganglioside induced differentiation associated protein
           2 isoform b [Homo sapiens]
          Length = 496

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 51  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81

Query: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137

Query: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93

Query: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150

Query: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207

Query: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471
                     E     K+L L     P+S +EE R
Sbjct: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232


>gi|8923143 ganglioside induced differentiation associated protein 2
           isoform a [Homo sapiens]
          Length = 497

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 51  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81

Query: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137

Query: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93

Query: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150

Query: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207

Query: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471
                     E     K+L L     P+S +EE R
Sbjct: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 18/170 (10%)

Query: 503 LSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVV 562
           L  QN  ++  NH L + + E       Q  + VS+ E        + I      L E +
Sbjct: 241 LRQQNACLVTQNHSL-MTKFESIHFELTQSRAKVSMLESAQQQAASVPI------LEEQI 293

Query: 563 MNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQ 622
           +N+E  +   Q+++ R+ E  L +S  +  I+++++  E KE  I LK       +LL+Q
Sbjct: 294 INLEAEV-SAQDKVLREAENKLEQSQ-KMVIEKEQSLQESKEECIKLKV------DLLEQ 345

Query: 623 KKQFEKCGLQVLKVEKIDN-EVLMAAFQRKKKMMEEKLHRQPVSHRLFQQ 671
            KQ ++   Q  + E + N E L  AFQ+ KK + EKL +      + ++
Sbjct: 346 TKQGKRAERQ--RNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILER 393


>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
          Length = 1498

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 52/245 (21%), Positives = 99/245 (40%), Gaps = 12/245 (4%)

Query: 424 KHQLTVKFVIFPTDLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR-----ENGLEAR 478
           K +L  +     T L+     S    +R   LS    ++ QS  + +R     +N LEA+
Sbjct: 435 KAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAK 494

Query: 479 SPAINLMGFNVEEMYEAHAWIQ-RILSLQNHHIIENNHILYLGRKEHDILSQLQKTSSVS 537
           + ++     +++   E +  +  ++  +Q   + ++N +  L ++   + SQLQ+     
Sbjct: 495 NASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLER 554

Query: 538 ITEIISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQK 597
            T       ++ EI    + L  V    +  L   QE   R +       +GQ T  Q  
Sbjct: 555 TTLTSKLKASQAEI----SSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMT--QAG 608

Query: 598 TQDEMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEE 657
             + +K   + L   +  TQ    ++K      LQ ++ + +D E      Q  K M+EE
Sbjct: 609 LLEHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEE 668

Query: 658 KLHRQ 662
            L R+
Sbjct: 669 DLQRR 673


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 37/201 (18%), Positives = 85/201 (42%), Gaps = 36/201 (17%)

Query: 473  NGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQK 532
            + L++     +L+    EE  EA A +QR+LS  N  + +     +  + E D + + ++
Sbjct: 1331 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ-----WRTKYETDAIQRTEE 1385

Query: 533  TSSV--SITEIISPGRTELEIEGARADLIEVVMN-----IEDMLCKVQEEMAR-----KK 580
                   + + +      +E   A+   +E   +     IED++  V+   A      KK
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445

Query: 581  ERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKID 640
            +R   + L +W  + +++Q E++ +                 +K+      ++ K++   
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESS-----------------QKEARSLSTELFKLKNAY 1488

Query: 641  NEVL--MAAFQRKKKMMEEKL 659
             E L  +  F+R+ K ++E++
Sbjct: 1489 EESLEHLETFKRENKNLQEEI 1509


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 37/201 (18%), Positives = 85/201 (42%), Gaps = 36/201 (17%)

Query: 473  NGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQNHHIIENNHILYLGRKEHDILSQLQK 532
            + L++     +L+    EE  EA A +QR+LS  N  + +     +  + E D + + ++
Sbjct: 1333 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ-----WRTKYETDAIQRTEE 1387

Query: 533  TSSV--SITEIISPGRTELEIEGARADLIEVVMN-----IEDMLCKVQEEMAR-----KK 580
                   + + +      +E   A+   +E   +     IED++  V+   A      KK
Sbjct: 1388 LEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1447

Query: 581  ERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQFEKCGLQVLKVEKID 640
            +R   + L +W  + +++Q E++ +                 +K+      ++ K++   
Sbjct: 1448 QRNFDKILAEWKQKYEESQSELESS-----------------QKEARSLSTELFKLKNAY 1490

Query: 641  NEVL--MAAFQRKKKMMEEKL 659
             E L  +  F+R+ K ++E++
Sbjct: 1491 EESLEHLETFKRENKNLQEEI 1511


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 32/132 (24%), Positives = 65/132 (49%), Gaps = 17/132 (12%)

Query: 533 TSSVSITEIISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWT 592
           +S+ +++ ++S G   L  E A  +++E+   +   L + +++    KE+     L  + 
Sbjct: 265 SSATNVSMVVSAG--PLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFL 322

Query: 593 IQQQK--TQDEMKENIIFLKCPVPPTQELLDQKKQF--EKCGLQVLKVEKI-DNEVLMAA 647
             QQK    +E K+ I F          +L  ++QF  EK   Q+ + E++   +VL+ A
Sbjct: 323 ANQQKKYKYEECKDLIKF----------MLRNERQFKEEKLAEQLKQAEELRQYKVLVHA 372

Query: 648 FQRKKKMMEEKL 659
            +R+   ++EKL
Sbjct: 373 QERELTQLKEKL 384


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 17/132 (12%)

Query: 533 TSSVSITEIISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWT 592
           +S+ +++ ++S G   L  E A  +++E+   +   L + +++    KER     L  + 
Sbjct: 265 SSATNVSMVVSAG--PLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFL 322

Query: 593 IQQQK--TQDEMKENIIFLKCPVPPTQELLDQKKQF--EKCGLQVLKVEKI-DNEVLMAA 647
             QQK    +E K+ I          + +L  ++QF  EK   Q+ + E++   +VL+ A
Sbjct: 323 ANQQKKYKYEECKDLI----------KSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHA 372

Query: 648 FQRKKKMMEEKL 659
            +R+   + EKL
Sbjct: 373 QERELTQLREKL 384


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 17/132 (12%)

Query: 533 TSSVSITEIISPGRTELEIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWT 592
           +S+ +++ ++S G   L  E A  +++E+   +   L + +++    KER     L  + 
Sbjct: 14  SSATNVSMVVSAG--PLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFL 71

Query: 593 IQQQK--TQDEMKENIIFLKCPVPPTQELLDQKKQF--EKCGLQVLKVEKI-DNEVLMAA 647
             QQK    +E K+ I          + +L  ++QF  EK   Q+ + E++   +VL+ A
Sbjct: 72  ANQQKKYKYEECKDLI----------KSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHA 121

Query: 648 FQRKKKMMEEKL 659
            +R+   + EKL
Sbjct: 122 QERELTQLREKL 133


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 24/185 (12%)

Query: 514 NHILYLGRKEHDILS-----------QLQKTSSVSITEIISPGRTELE-----IEGARAD 557
           NH LY+ R++ D +            + QK    ++ E     R   E     IE  + +
Sbjct: 287 NHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEE 346

Query: 558 LIEVVMNIEDMLCKVQEEMARKKERGL--------WRSLGQWTIQQQKTQDEMKENIIFL 609
           L+E +  IE+   K Q+E+  +  R L         +S  +   ++++  +E KE ++  
Sbjct: 347 LMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQA 406

Query: 610 KCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLF 669
                 TQE L  +       +  L++ +   E     +Q+K +M++E L +     +  
Sbjct: 407 SRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTA 466

Query: 670 QQVPY 674
              P+
Sbjct: 467 MSTPH 471


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 48/216 (22%), Positives = 91/216 (42%), Gaps = 22/216 (10%)

Query: 445 SSEMAKRSKMLSLNNYSVPQSTREEKRENGL---EARSPAINLMGFNV-----EEMYEAH 496
           S E+ K+   L+L N ++ +   +   +N L   +A +  I +    V     E+M ++H
Sbjct: 685 SGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSH 744

Query: 497 AWIQRILSLQNHHIIENNHILYLGRKEHDIL----SQLQKTSSVSITEIISPGRTELEIE 552
                I+   N  +++        + E + L      L K  S   T  + P + E EI 
Sbjct: 745 ---DAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEII 801

Query: 553 GARADLIEVVMNIEDMLCKVQEEM----ARKKERGLWRSLGQWTIQQQKTQDEMKENIIF 608
             +++++E+   + ++  K  E+     A   E    + +        KT +E+K  +  
Sbjct: 802 ALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLND 861

Query: 609 LKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVL 644
                   +ELLD KK+FE    + +K+ K  NE+L
Sbjct: 862 TLAKT--NRELLDVKKKFEDINQEFVKI-KDKNEIL 894


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 48/216 (22%), Positives = 91/216 (42%), Gaps = 22/216 (10%)

Query: 445 SSEMAKRSKMLSLNNYSVPQSTREEKRENGL---EARSPAINLMGFNV-----EEMYEAH 496
           S E+ K+   L+L N ++ +   +   +N L   +A +  I +    V     E+M ++H
Sbjct: 698 SGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSH 757

Query: 497 AWIQRILSLQNHHIIENNHILYLGRKEHDIL----SQLQKTSSVSITEIISPGRTELEIE 552
                I+   N  +++        + E + L      L K  S   T  + P + E EI 
Sbjct: 758 ---DAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEII 814

Query: 553 GARADLIEVVMNIEDMLCKVQEEM----ARKKERGLWRSLGQWTIQQQKTQDEMKENIIF 608
             +++++E+   + ++  K  E+     A   E    + +        KT +E+K  +  
Sbjct: 815 ALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLND 874

Query: 609 LKCPVPPTQELLDQKKQFEKCGLQVLKVEKIDNEVL 644
                   +ELLD KK+FE    + +K+ K  NE+L
Sbjct: 875 TLAKT--NRELLDVKKKFEDINQEFVKI-KDKNEIL 907


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 30/126 (23%)

Query: 547  TEL--EIEGARADLIEVVMNIEDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKE 604
            TEL  E E  RA L      +E++L  ++  +  ++ER             Q  Q+E K+
Sbjct: 900  TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERN------------QILQNEKKK 947

Query: 605  NIIFLKCPVPPTQELLD------QKKQFEKCGLQVLKVEKIDNEVLM-----AAFQRKKK 653
                ++  +   +E LD      QK Q EK   +  K++K++ E+L+     + F ++KK
Sbjct: 948  ----MQAHIQDLEEQLDEEEGARQKLQLEKVTAEA-KIKKMEEEILLLEDQNSKFIKEKK 1002

Query: 654  MMEEKL 659
            +ME+++
Sbjct: 1003 LMEDRI 1008


>gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Homo
           sapiens]
          Length = 1025

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 15/68 (22%), Positives = 35/68 (51%), Gaps = 3/68 (4%)

Query: 628 KCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQR 687
           +  ++V++VE++ + +L   ++  ++ + ++  R+PV   L+          +C  GF R
Sbjct: 845 RSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNR 904

Query: 688 MYSTPCGR 695
            +   CGR
Sbjct: 905 SF---CGR 909


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,452,420
Number of Sequences: 37866
Number of extensions: 1075327
Number of successful extensions: 3043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2947
Number of HSP's gapped (non-prelim): 97
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.