Search of human proteins with 225903424

Search of human proteins with 225903424

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225903424 TatD DNase domain containing 2 [Homo sapiens]
         (761 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225903424 TatD DNase domain containing 2 [Homo sapiens]           1548   0.0  
gi|225903439 TatD DNase domain containing 1 isoform b [Homo sapi...    69   1e-11
gi|14042943 TatD DNase domain containing 1 isoform a [Homo sapiens]    69   1e-11
gi|110349730 TatD DNase domain containing 3 isoform 1 [Homo sapi...    49   2e-05
gi|226061853 TatD DNase domain containing 3 isoform 5 [Homo sapi...    48   4e-05
gi|110349734 TatD DNase domain containing 3 isoform 2 [Homo sapi...    47   7e-05
gi|226061595 TatD DNase domain containing 3 isoform 3 [Homo sapi...    47   9e-05
gi|150456424 RW1 protein [Homo sapiens]                                44   4e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    43   0.001
gi|226061614 TatD DNase domain containing 3 isoform 4 [Homo sapi...    42   0.002
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    42   0.002
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|171184451 centrosome-associated protein 350 [Homo sapiens]          42   0.003
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    41   0.004
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    41   0.004
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    41   0.004
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         40   0.006
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    40   0.006
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    40   0.006
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    40   0.008
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          39   0.014
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          39   0.014
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          39   0.014
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    39   0.018
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    39   0.018
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    39   0.018
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    39   0.018
gi|153070260 myristoylated alanine-rich protein kinase C substra...    39   0.018
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     39   0.018
gi|50962882 G patch domain containing 8 [Homo sapiens]                 39   0.018

>gi|225903424 TatD DNase domain containing 2 [Homo sapiens]
          Length = 761

 Score = 1548 bits (4008), Expect = 0.0
 Identities = 761/761 (100%), Positives = 761/761 (100%)

Query: 1   MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKE 60
           MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKE
Sbjct: 1   MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKE 60

Query: 61  DDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPA 120
           DDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPA
Sbjct: 61  DDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPA 120

Query: 121 NASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRD 180
           NASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRD
Sbjct: 121 NASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRD 180

Query: 181 QGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARS 240
           QGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARS
Sbjct: 181 QGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARS 240

Query: 241 VTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSP 300
           VTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSP
Sbjct: 241 VTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSP 300

Query: 301 PLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEP 360
           PLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEP
Sbjct: 301 PLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEP 360

Query: 361 SSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS 420
           SSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS
Sbjct: 361 SSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS 420

Query: 421 PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASS 480
           PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASS
Sbjct: 421 PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASS 480

Query: 481 SLPKSHLEPSLEEGFIDTHCHLDMLYSKLSFQGTFTKFRKIYSSSFPKEFQGCISDFCDP 540
           SLPKSHLEPSLEEGFIDTHCHLDMLYSKLSFQGTFTKFRKIYSSSFPKEFQGCISDFCDP
Sbjct: 481 SLPKSHLEPSLEEGFIDTHCHLDMLYSKLSFQGTFTKFRKIYSSSFPKEFQGCISDFCDP 540

Query: 541 RTLTDCLWEELLKEDLVWGAFGCHPHFARYYSESQERNLLQALRHPKAVAFGEMGLDYSY 600
           RTLTDCLWEELLKEDLVWGAFGCHPHFARYYSESQERNLLQALRHPKAVAFGEMGLDYSY
Sbjct: 541 RTLTDCLWEELLKEDLVWGAFGCHPHFARYYSESQERNLLQALRHPKAVAFGEMGLDYSY 600

Query: 601 KCTTPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGS 660
           KCTTPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGS
Sbjct: 601 KCTTPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGS 660

Query: 661 YPVIEPLLKYFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPYFLPRQVPKSL 720
           YPVIEPLLKYFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPYFLPRQVPKSL
Sbjct: 661 YPVIEPLLKYFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPYFLPRQVPKSL 720

Query: 721 CQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLYSL 761
           CQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLYSL
Sbjct: 721 CQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLYSL 761


>gi|225903439 TatD DNase domain containing 1 isoform b [Homo
           sapiens]
          Length = 250

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 556 LVWGAFGCHPHFARYYSESQERNLLQALRH------PKAVAFGEMGLDYSYKCTTPVPEQ 609
           + +   GCHP     + ++     L+ L +       K VA GE GLD+      P   Q
Sbjct: 22  MFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQ 81

Query: 610 HKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGSYPVIEPLLK 669
            K FE+Q +L+   K P+ +HCR +  + L+IMK+          H F G+      L+ 
Sbjct: 82  LKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALID 141

Query: 670 YFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPY 710
              ++ +GF      + A    E L+ IP E++++ETDAP+
Sbjct: 142 L--DLYIGFNGCSLKTEA--NLEVLKSIPSEKLMIETDAPW 178


>gi|14042943 TatD DNase domain containing 1 isoform a [Homo sapiens]
          Length = 297

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 556 LVWGAFGCHPHFARYYSESQERNLLQALRH------PKAVAFGEMGLDYSYKCTTPVPEQ 609
           + +   GCHP     + ++     L+ L +       K VA GE GLD+      P   Q
Sbjct: 69  MFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQ 128

Query: 610 HKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGSYPVIEPLLK 669
            K FE+Q +L+   K P+ +HCR +  + L+IMK+          H F G+      L+ 
Sbjct: 129 LKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALID 188

Query: 670 YFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPY 710
              ++ +GF      + A    E L+ IP E++++ETDAP+
Sbjct: 189 L--DLYIGFNGCSLKTEA--NLEVLKSIPSEKLMIETDAPW 225


>gi|110349730 TatD DNase domain containing 3 isoform 1 [Homo
           sapiens]
          Length = 274

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 18/178 (10%)

Query: 587 KAVAFGEMGLDYSYKCT---TPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMK 643
           + +A GE+GLD+S +         EQ +V  RQ+QLA  L  P+ +H R A    + +++
Sbjct: 101 RLLAIGEVGLDFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQ 160

Query: 644 KFVPPDYKIHRHCFTGSYPVIEPLLK--YFPNMSVGFTAVLTYSSAWEAREALRQIPLER 701
           +      K+  H F G   V    ++  YF      F+   +   + + ++ ++Q+PL  
Sbjct: 161 E--QGAEKVLLHAFDGRPSVAMEGVRAGYF------FSIPPSIIRSGQKQKLVKQLPLTS 212

Query: 702 IIVETDAPYFLPRQVPKSLCQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLY 759
           I +ETD+P   P +  ++      P     +   IA+VK   +   +    +N  +L+
Sbjct: 213 ICLETDSPALGPEKQVRN-----EPWNISISAEYIAQVKGISVEEVIEVTTQNALKLF 265


>gi|226061853 TatD DNase domain containing 3 isoform 5 [Homo
           sapiens]
          Length = 281

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 45/179 (25%), Positives = 81/179 (45%), Gaps = 13/179 (7%)

Query: 587 KAVAFGEMGLDYSYKCT---TPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMK 643
           + +A GE+GLD+S +         EQ +V  RQ+QLA  L  P+ +H R A    + +++
Sbjct: 101 RLLAIGEVGLDFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQ 160

Query: 644 KFVPPDYKIHRHCFTGSYPVIEPLLK--YFPNMSVGFTAVLTYSSAWEAREAL-RQIPLE 700
           +      K+  H F G   V    ++  YF ++           S +  ++ L +Q+PL 
Sbjct: 161 E--QGAEKVLLHAFDGRPSVAMEGVRAGYFFSIPPSIIRSGQLLSLFSKKQKLVKQLPLT 218

Query: 701 RIIVETDAPYFLPRQVPKSLCQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLY 759
            I +ETD+P   P +  ++      P     +   IA+VK   +   +    +N  +L+
Sbjct: 219 SICLETDSPALGPEKQVRN-----EPWNISISAEYIAQVKGISVEEVIEVTTQNALKLF 272


>gi|110349734 TatD DNase domain containing 3 isoform 2 [Homo
           sapiens]
          Length = 273

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 44/177 (24%), Positives = 78/177 (44%), Gaps = 17/177 (9%)

Query: 587 KAVAFGEMGLDYSYKCT---TPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMK 643
           + +A GE+GLD+S +         EQ +V  RQ+QLA  L  P+ +H R A    + +++
Sbjct: 101 RLLAIGEVGLDFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQ 160

Query: 644 KFVPPDYKIHRHCFTGSYPVIEPLLKYFPNMSVGFTAVLTYSSAWEAREAL-RQIPLERI 702
           +      K+  H F G   V          +  G+   +  S     ++ L +Q+PL  I
Sbjct: 161 E--QGAEKVLLHAFDGRPSVA------MEGVRAGYFFSIPPSIIRSGQQKLVKQLPLTSI 212

Query: 703 IVETDAPYFLPRQVPKSLCQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLY 759
            +ETD+P   P +  ++      P     +   IA+VK   +   +    +N  +L+
Sbjct: 213 CLETDSPALGPEKQVRN-----EPWNISISAEYIAQVKGISVEEVIEVTTQNALKLF 264


>gi|226061595 TatD DNase domain containing 3 isoform 3 [Homo
           sapiens]
          Length = 240

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 8/135 (5%)

Query: 587 KAVAFGEMGLDYSYKCT---TPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMK 643
           + +A GE+GLD+S +         EQ +V  RQ+QLA  L  P+ +H R A    + +++
Sbjct: 101 RLLAIGEVGLDFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQ 160

Query: 644 KFVPPDYKIHRHCFTGSYPVIEPLLK--YFPNMSVGFTAVLTYSSAWEAREAL-RQIPLE 700
           +      K+  H F G   V    ++  YF ++           S +  ++ L +Q+PL 
Sbjct: 161 E--QGAEKVLLHAFDGRPSVAMEGVRAGYFFSIPPSIIRSGQLLSLFSKKQKLVKQLPLT 218

Query: 701 RIIVETDAPYFLPRQ 715
            I +ETD+P   P +
Sbjct: 219 SICLETDSPALGPEK 233


>gi|150456424 RW1 protein [Homo sapiens]
          Length = 1883

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 93/434 (21%), Positives = 160/434 (36%), Gaps = 79/434 (18%)

Query: 71   WGSSRRRNNSSSSFSPHFLGPG-----VGGAASKG------CLIRNTRGFLSSGGSPLRP 119
            W   RRR +  +S  P  +G       + G +S+G      C   ++RGF  +GGS  RP
Sbjct: 1147 WEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRP 1206

Query: 120  ANASLEEMA-------------SLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEE 166
            +  S ++               S + E    K  S  SS  S  +  +  A   +  + +
Sbjct: 1207 SAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLD 1266

Query: 167  PNKV-------QKRKRDRLRDQGSTMIYLKAI----QGILGKSMPKRKGEAATRAKPSAA 215
             N V       +K K  +    GS       +    Q  L   +P+ +     R  P+  
Sbjct: 1267 SNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPL 1326

Query: 216  EHPSHGEGPARSEGPAKTAEGAARSVTVTAAQKEKD----ATPEVSMEEDKTVPERSSFY 271
             HPSH   P R+     ++E +  +  + A  K+ D       EV  E+  +   +S   
Sbjct: 1327 AHPSH---PERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGK 1383

Query: 272  DR---RVVIDPQE----------KPSEEPLGDRRTVIDKCSPPLEFLDDSDSHL---EIQ 315
             +   R V  P++          KP E+ L D     D  S   E  +     L   + +
Sbjct: 1384 GKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTE 1443

Query: 316  KHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLY 375
            K K ++ + E   S       +    +   +E P  +KPS++  P         Y P L 
Sbjct: 1444 KQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELP---------YTPPLE 1494

Query: 376  SSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSR------SRMSDYSPNS--TGSV 427
            S    +  S     P P++  S GS S +A +   +S+        ++ + PNS   G+ 
Sbjct: 1495 SKQRRNLPS---KIPLPTAMTS-GSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNT 1550

Query: 428  QNTSRDMEASEEGW 441
             ++  + ++    W
Sbjct: 1551 SSSEGEKDSPPPEW 1564


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 73/352 (20%), Positives = 136/352 (38%), Gaps = 38/352 (10%)

Query: 154 AAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPK-RKGEAATRAKP 212
           +++++  + + +EP K QK K   +  +  T    K       ++ PK   G+AA+ +  
Sbjct: 166 SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKP-----ARAAPKIANGKAASSSSS 220

Query: 213 SAAEHPSH-GEGPARSEGPAKT-------AEGAARSVTVTAAQKEKDATPEVSMEEDKTV 264
           S++   S   E    +  P KT       A+   ++ T    +           EE++  
Sbjct: 221 SSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280

Query: 265 PERSSFYDRRVVIDPQEKPSEEPLGDR--RTVIDKCSP---PLEFLDDSDSHLEIQKHKD 319
           P ++       V  P   P ++ LG +  +  ++K  P     +  D+SDS  E +K   
Sbjct: 281 PMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPP 340

Query: 320 REVVMEHPS-----------SGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYV 368
            + V+   +           S SD SD +  S    +  +P     ++  +P+  T    
Sbjct: 341 TKAVVSKATTKPPPAKKAAESSSDSSDSDS-SEDDEAPSKPAGTTKNSSNKPAVTTKSPA 399

Query: 369 MYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQ 428
           + P      P        T     SS     SSS +     + ++  ++   P +T    
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE-----EKTKKMVATTKPKATAKAA 454

Query: 429 NTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASS 480
            +    +A +   S++S S   S SSEE E K  ++  ++ P +  GG A S
Sbjct: 455 LSLPAKQAPQG--SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPS 504


>gi|226061614 TatD DNase domain containing 3 isoform 4 [Homo
           sapiens]
          Length = 253

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 18/172 (10%)

Query: 593 EMGLDYSYKCT---TPVPEQHKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPD 649
           ++GLD+S +         EQ +V  RQ+QLA  L  P+ +H R A    + ++++     
Sbjct: 86  KVGLDFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQE--QGA 143

Query: 650 YKIHRHCFTGSYPVIEPLLK--YFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETD 707
            K+  H F G   V    ++  YF      F+   +   + + ++ ++Q+PL  I +ETD
Sbjct: 144 EKVLLHAFDGRPSVAMEGVRAGYF------FSIPPSIIRSGQKQKLVKQLPLTSICLETD 197

Query: 708 APYFLPRQVPKSLCQYAHPGLALHTVREIARVKDQPLSLTLAALRENTSRLY 759
           +P   P +  ++      P     +   IA+VK   +   +    +N  +L+
Sbjct: 198 SPALGPEKQVRN-----EPWNISISAEYIAQVKGISVEEVIEVTTQNALKLF 244


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 108/528 (20%), Positives = 186/528 (35%), Gaps = 110/528 (20%)

Query: 20   PRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNN 79
            PR+ +CL E        R +  S+ +S      K+ KA+K++          G SR+   
Sbjct: 1334 PRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEK---GEDYKEGGSRK--- 1387

Query: 80   SSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKV 139
             S  +   FL     G +                        A +E+      E  S + 
Sbjct: 1388 DSGQYEKDFLEADAYGVSYN--------------------MKADIEDELDKTIELFSTEK 1427

Query: 140  DSKDSSHNSTNSEFAAEAEGQNDT----IEEPNKVQKRK------RDRLRDQGSTMIYLK 189
              K+ S    + +   E +    +    ++E  K +K +      ++R RD+ +  +   
Sbjct: 1428 KDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRH 1487

Query: 190  AIQGILGKSMPKRKGEAATRAK---PSAAEHPSHGEGPARSEGPAKTA--EGAARS---- 240
                +L     ++K   ATR K   P   +  S  EGP   +   K    +GA +     
Sbjct: 1488 HRDELLRHHRDEQK--PATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDP 1545

Query: 241  ---------VTVTAAQKEKDATPEVSM----------------EEDKTVPERSSFYDRRV 275
                     V  +    +KDA P   +                ++D  + ER   +  R+
Sbjct: 1546 VKMSNGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERM 1605

Query: 276  VI---------DPQEKPSEEPLGD-RRTVIDKCSPPLEFLDDSDSHLEIQKHKDREVVME 325
                       DP+ K   +P  D R+  +D  +     LD      ++++        E
Sbjct: 1606 KQMEKLRHRSGDPKLKEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAE 1665

Query: 326  ---HPSSGSD---WSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTT----DYVMYPPHLY 375
               HP+SG+D   W     +  V  +   P   +P+ VP P+S  +    + VM+ P   
Sbjct: 1666 NKLHPASGADSKDWLAGPHMKEVLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTP 1725

Query: 376  SSPWCDYASY-------WTSSPKPSSYPSTGSSS----NDAAQVGKSSRSRMSDYSPNST 424
            S    DYA           S+P P++  S  S S       A  G S  +  +   P ST
Sbjct: 1726 SCSADDYADLVFDCADSQHSTPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLST 1785

Query: 425  GSVQNTSRDMEAS-EEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPP 471
               ++ S D+  + EE +S   + FR      ++ V    ++   MPP
Sbjct: 1786 NLYRSVSVDIRRTPEEEFSVGDKLFR------QQSVPAASSYDSPMPP 1827


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 328 SSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMY--PPHLYSSPWCDYASY 385
           SS S W+      T   +     S   ++ P  S + +  V +  P   ++S   D+   
Sbjct: 158 SSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFG-- 215

Query: 386 WTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNS 445
           W S+P  S + S+ +S    +  G S+ S     SP+++    +TSR   +S+ GW+ +S
Sbjct: 216 WASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSS 275

Query: 446 RSF 448
            S+
Sbjct: 276 ASW 278



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 27/122 (22%), Positives = 46/122 (37%), Gaps = 3/122 (2%)

Query: 329 SGSDW--SDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYW 386
           SGS W  S     ST   S     S   +++P  S + +          +S W  +++ W
Sbjct: 16  SGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASW 75

Query: 387 TSSPKPSSYPSTGSS-SNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNS 445
            S P  S + S  +S ++  +  G +S S      P+ +G    +          W+  S
Sbjct: 76  ASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPS 135

Query: 446 RS 447
            S
Sbjct: 136 AS 137


>gi|171184451 centrosome-associated protein 350 [Homo sapiens]
          Length = 3117

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 75/315 (23%), Positives = 120/315 (38%), Gaps = 71/315 (22%)

Query: 219  SHGEGPARSEGPAKTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVID 278
            S  EGP  SEG     EG            ++D  P + + E   + +   F        
Sbjct: 981  SVSEGPLLSEGSLSEEEG------------DQDGQPLLKVAE---ILKEKEFC------- 1018

Query: 279  PQEKPSEEPLGDRRTVIDKCSPPLEFLDDSDSH---LEIQKHKDREVVMEHPSS----GS 331
            P E+ S EP+ + +   +K  P    +  + S     E+ K     V+     S    G 
Sbjct: 1019 PGERNSYEPIKEFQKEAEKFLPLFGHIGGTQSKGPWEELAKGSPHSVINIFTKSYQLYGK 1078

Query: 332  DWSDVEEISTVRFSQEEPVSLKPSAVPEPS-SFTTDYVMYP-------------PHLYSS 377
             + D  +  T   S   P  L  +A P    S+  D+V  P             PH   S
Sbjct: 1079 GFEDKLDRGT---STSRP--LNATATPLSGVSYEDDFVSSPGTGTSTEKKSTLEPHSTLS 1133

Query: 378  PWCDYAS----YWTSSPKPSSYPSTG-----SSSNDAAQVGKSSRSRMSDYSPNSTGSVQ 428
            P  D+++    Y  SS   +S  S+G     SS +  +  GK  +   +++  + TG+VQ
Sbjct: 1134 PQEDHSNRKSAYDPSSVDVTSQHSSGAQSAASSRSSTSSKGKKGKKEKTEWLDSFTGNVQ 1193

Query: 429  NTSRDMEASEEGWSQNSRSFRFSRSSEEREVKE-KRTFQEEMPPRPCGGHA--------- 478
            N+  D E +E G  Q  +    S +S +  VK+ ++T   +       GH+         
Sbjct: 1194 NSLLDEEKAERGSHQGKK----SGTSSKLSVKDFEQTLDTDSTLEDLSGHSVSVSSDKGR 1249

Query: 479  SSSLPKSHLEPSLEE 493
            S   P S L PS ++
Sbjct: 1250 SQKTPTSPLSPSSQK 1264


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 73/358 (20%), Positives = 132/358 (36%), Gaps = 63/358 (17%)

Query: 78  NNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSL 137
           +   S    H++G G  G +S G             GS L       ++  S+  E  + 
Sbjct: 183 STQESESEEHWVGGGSDGESSHG------------DGSELDDEGMQSDDPESIRSERGNS 230

Query: 138 KVDSKD--SSHNSTNSEFA-AEAEGQNDTIEEPN-KVQKRKRDRLRDQGSTMIYLKAIQG 193
           +++S    S  +  NSE A  +  G +  +E P+ K+ ++ R    D  S +     ++ 
Sbjct: 231 RMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEE 290

Query: 194 ILGKSMPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARSVTVTAAQKEKDAT 253
           +   S           ++P             R +    + E +  +++   +Q     +
Sbjct: 291 VKSDSTENSNSRDTGLSQP-------------RRDSKGDSQEDSKENLSQEESQNVDGPS 337

Query: 254 PEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSPPLEFLDDSDSHLE 313
            E S E + +  E SS        + QE+   E  GD     D  +  +E  +DSDS  E
Sbjct: 338 SESSQEANLSSQENSS--------ESQEEVVSESRGDNP---DPTTSYVEDQEDSDSSEE 386

Query: 314 IQKHKDREVVMEHPSSGS--DWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYP 371
              H      + H  S S  + +D E   ++ FS+E P S      PE  + ++   +  
Sbjct: 387 DSSH-----TLSHSKSESREEQADSESSESLNFSEESPES------PEDENSSSQEGLQ- 434

Query: 372 PHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQN 429
                     ++S   S  + S      S S D+++  + S S  S  S    G ++N
Sbjct: 435 ---------SHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKN 483



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 84/386 (21%), Positives = 139/386 (36%), Gaps = 74/386 (19%)

Query: 132 EEACSLKVDSKDSSHNSTNSEFAAEAEGQN---DTIEEPNKVQKRKRDRLRDQGSTMIYL 188
           +E  + ++ S + S ++  +   +  +GQ+   DT  E  ++    R   + +G      
Sbjct: 127 QEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEG------ 180

Query: 189 KAIQGILGKSMPKRKGEAATRAKPSAAEHPSHGEGPA------RSEGPA--KTAEGAARS 240
                  G S  + + E       S  E  SHG+G        +S+ P   ++  G +R 
Sbjct: 181 -------GDSTQESESEEHWVGGGSDGES-SHGDGSELDDEGMQSDDPESIRSERGNSRM 232

Query: 241 VTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSP 300
            +     KE     E +  +D    +      R++    + + SEE   D R+ +D  + 
Sbjct: 233 NSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIF--RKSRISEE---DDRSELDDNNT 287

Query: 301 PLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEP 360
             E   DS      +    R+  +  P   S   D +E S    SQEE  +     V  P
Sbjct: 288 MEEVKSDST-----ENSNSRDTGLSQPRRDSK-GDSQEDSKENLSQEESQN-----VDGP 336

Query: 361 SSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS 420
           SS                          S + ++  S  +SS    +V   SR      +
Sbjct: 337 SS-------------------------ESSQEANLSSQENSSESQEEVVSESRGD----N 367

Query: 421 PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEER---EVKEKRTFQEEMPPRPCGGH 477
           P+ T S      D ++SEE  S ++ S   S S EE+   E  E   F EE P  P   +
Sbjct: 368 PDPTTSYVEDQEDSDSSEED-SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDEN 426

Query: 478 ASSSLPKSHLEPSLEEGFIDTHCHLD 503
           +SS         S E    ++H   D
Sbjct: 427 SSSQEGLQSHSSSAESQSEESHSEED 452


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 73/358 (20%), Positives = 132/358 (36%), Gaps = 63/358 (17%)

Query: 78  NNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSL 137
           +   S    H++G G  G +S G             GS L       ++  S+  E  + 
Sbjct: 167 STQESESEEHWVGGGSDGESSHG------------DGSELDDEGMQSDDPESIRSERGNS 214

Query: 138 KVDSKD--SSHNSTNSEFA-AEAEGQNDTIEEPN-KVQKRKRDRLRDQGSTMIYLKAIQG 193
           +++S    S  +  NSE A  +  G +  +E P+ K+ ++ R    D  S +     ++ 
Sbjct: 215 RMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEE 274

Query: 194 ILGKSMPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARSVTVTAAQKEKDAT 253
           +   S           ++P             R +    + E +  +++   +Q     +
Sbjct: 275 VKSDSTENSNSRDTGLSQP-------------RRDSKGDSQEDSKENLSQEESQNVDGPS 321

Query: 254 PEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSPPLEFLDDSDSHLE 313
            E S E + +  E SS        + QE+   E  GD     D  +  +E  +DSDS  E
Sbjct: 322 SESSQEANLSSQENSS--------ESQEEVVSESRGDNP---DPTTSYVEDQEDSDSSEE 370

Query: 314 IQKHKDREVVMEHPSSGS--DWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYP 371
              H      + H  S S  + +D E   ++ FS+E P S      PE  + ++   +  
Sbjct: 371 DSSH-----TLSHSKSESREEQADSESSESLNFSEESPES------PEDENSSSQEGLQ- 418

Query: 372 PHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQN 429
                     ++S   S  + S      S S D+++  + S S  S  S    G ++N
Sbjct: 419 ---------SHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKN 467



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 84/386 (21%), Positives = 139/386 (36%), Gaps = 74/386 (19%)

Query: 132 EEACSLKVDSKDSSHNSTNSEFAAEAEGQN---DTIEEPNKVQKRKRDRLRDQGSTMIYL 188
           +E  + ++ S + S ++  +   +  +GQ+   DT  E  ++    R   + +G      
Sbjct: 111 QEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEG------ 164

Query: 189 KAIQGILGKSMPKRKGEAATRAKPSAAEHPSHGEGPA------RSEGPA--KTAEGAARS 240
                  G S  + + E       S  E  SHG+G        +S+ P   ++  G +R 
Sbjct: 165 -------GDSTQESESEEHWVGGGSDGES-SHGDGSELDDEGMQSDDPESIRSERGNSRM 216

Query: 241 VTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSP 300
            +     KE     E +  +D    +      R++    + + SEE   D R+ +D  + 
Sbjct: 217 NSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIF--RKSRISEE---DDRSELDDNNT 271

Query: 301 PLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEP 360
             E   DS      +    R+  +  P   S   D +E S    SQEE  +     V  P
Sbjct: 272 MEEVKSDST-----ENSNSRDTGLSQPRRDSK-GDSQEDSKENLSQEESQN-----VDGP 320

Query: 361 SSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS 420
           SS                          S + ++  S  +SS    +V   SR      +
Sbjct: 321 SS-------------------------ESSQEANLSSQENSSESQEEVVSESRGD----N 351

Query: 421 PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEER---EVKEKRTFQEEMPPRPCGGH 477
           P+ T S      D ++SEE  S ++ S   S S EE+   E  E   F EE P  P   +
Sbjct: 352 PDPTTSYVEDQEDSDSSEED-SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDEN 410

Query: 478 ASSSLPKSHLEPSLEEGFIDTHCHLD 503
           +SS         S E    ++H   D
Sbjct: 411 SSSQEGLQSHSSSAESQSEESHSEED 436


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 11/101 (10%)

Query: 29  PCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSR------RRNNSSS 82
           P   AP+S P + S ++S GP+    +K +K  ++   RRLS    R      R   + S
Sbjct: 142 PQGAAPASPPTKASRTKSPGPARRLSIKMKKLPELR--RRLSLRGPRAGRERERAAPAGS 199

Query: 83  SFSPHFLGPGVGG---AASKGCLIRNTRGFLSSGGSPLRPA 120
             S + L   VGG   AA  G       G+LS G SP RPA
Sbjct: 200 VISRYHLDSSVGGPGPAAGPGGTRSPRAGYLSDGDSPERPA 240


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 380  CDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEE 439
            C  AS   +SP  SS  S+ SSS+ ++    SS S  S  S +S+ S  ++S    +S  
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661

Query: 440  GWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLP 483
              S +S     S SS   E     +  E  P    G  A ++LP
Sbjct: 2662 SSSSSS-----SSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 34/149 (22%), Positives = 55/149 (36%), Gaps = 3/149 (2%)

Query: 28   EPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACS---RRLSWGSSRRRNNSSSSF 84
            E    + S   +  S+S S G  +    +  K  D  C    R  S  SSR  + +SSS 
Sbjct: 2558 ESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS 2617

Query: 85   SPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKVDSKDS 144
            S          ++S      ++    SS  S    +++S    +S    + S     +DS
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677

Query: 145  SHNSTNSEFAAEAEGQNDTIEEPNKVQKR 173
            S +S +    A   G +     P K  K+
Sbjct: 2678 SCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%)

Query: 46   SGGPSSPKRLKAQKE--DDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLI 103
            SG P SP + +A+++  ++   S   S GSS   ++SSSS S    G   G     G   
Sbjct: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS-ETEGEEEGDKNGDGGCG 2596

Query: 104  RNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDT 163
               R   ++      PA++S    +S    + S    S  SS +S++S  ++ +   + +
Sbjct: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 20/62 (32%), Positives = 32/62 (51%)

Query: 376  SSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDME 435
            +SP    +S  +SS   SS  S+ SSS+ ++    SS S  S  S +S+ S  ++S    
Sbjct: 2610 ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669

Query: 436  AS 437
            +S
Sbjct: 2670 SS 2671


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 63/285 (22%), Positives = 106/285 (37%), Gaps = 24/285 (8%)

Query: 13  SSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWG 72
           +S  +  P K++ +R P       R  +++ S S   S      A K + VA +R  S  
Sbjct: 199 TSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGA-KPEPVAMARSASSS 257

Query: 73  SSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEE 132
           SS    +SSSS S   +     G       +   RG       P RP ++S  +  S E 
Sbjct: 258 SS----SSSSSDSDVSVKKPPRGRKPAEKPLPKPRG---RKPKPERPPSSSSSDSDSDEV 310

Query: 133 EACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQ 192
           +  S      ++      +    E E +   + E  K +K +R    D+G      +A +
Sbjct: 311 DRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRG------EAER 364

Query: 193 GILGKS----------MPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARSVT 242
           G  G S          + KR  +   R  PS+++     E    ++  AK  + ++    
Sbjct: 365 GSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPA 424

Query: 243 VTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEP 287
               QKEK   PE   +      ER+        +D + +  +EP
Sbjct: 425 RKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEP 469



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 61/271 (22%), Positives = 96/271 (35%), Gaps = 45/271 (16%)

Query: 224 PARSEGPAKTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKP 283
           PA     +K A  A+  +   +    ++   E S E +KT  +  +   +  V      P
Sbjct: 160 PALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAV----RAP 215

Query: 284 SEEPLGDRRTVIDKCSPPLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVR 343
              PLG R+    K +P      DSDS  +    K   V M   +S S  S     S V 
Sbjct: 216 RRGPLGGRKK---KKAPSAS---DSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVS 269

Query: 344 FSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSN 403
             ++ P   KP+  P P                             PKP   PS+ SS +
Sbjct: 270 V-KKPPRGRKPAEKPLPKPRGR-----------------------KPKPERPPSSSSSDS 305

Query: 404 DAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKR 463
           D+ +V + S  +  D         +   R++EA      +        +  EE+E + +R
Sbjct: 306 DSDEVDRISEWKRRD---------EARRRELEARRRREQEEELRRLREQEKEEKERRRER 356

Query: 464 TFQEEMPPRPCGGHASSSLPKSHLEPSLEEG 494
             + E   R  GG +   L +   EP  + G
Sbjct: 357 ADRGE-AERGSGGSSGDELREDD-EPVKKRG 385


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 63/285 (22%), Positives = 106/285 (37%), Gaps = 24/285 (8%)

Query: 13  SSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWG 72
           +S  +  P K++ +R P       R  +++ S S   S      A K + VA +R  S  
Sbjct: 199 TSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGA-KPEPVAMARSASSS 257

Query: 73  SSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEE 132
           SS    +SSSS S   +     G       +   RG       P RP ++S  +  S E 
Sbjct: 258 SS----SSSSSDSDVSVKKPPRGRKPAEKPLPKPRG---RKPKPERPPSSSSSDSDSDEV 310

Query: 133 EACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQ 192
           +  S      ++      +    E E +   + E  K +K +R    D+G      +A +
Sbjct: 311 DRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRG------EAER 364

Query: 193 GILGKS----------MPKRKGEAATRAKPSAAEHPSHGEGPARSEGPAKTAEGAARSVT 242
           G  G S          + KR  +   R  PS+++     E    ++  AK  + ++    
Sbjct: 365 GSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPA 424

Query: 243 VTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEP 287
               QKEK   PE   +      ER+        +D + +  +EP
Sbjct: 425 RKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEP 469



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 61/271 (22%), Positives = 96/271 (35%), Gaps = 45/271 (16%)

Query: 224 PARSEGPAKTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKP 283
           PA     +K A  A+  +   +    ++   E S E +KT  +  +   +  V      P
Sbjct: 160 PALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAV----RAP 215

Query: 284 SEEPLGDRRTVIDKCSPPLEFLDDSDSHLEIQKHKDREVVMEHPSSGSDWSDVEEISTVR 343
              PLG R+    K +P      DSDS  +    K   V M   +S S  S     S V 
Sbjct: 216 RRGPLGGRKK---KKAPSAS---DSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVS 269

Query: 344 FSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSN 403
             ++ P   KP+  P P                             PKP   PS+ SS +
Sbjct: 270 V-KKPPRGRKPAEKPLPKPRGR-----------------------KPKPERPPSSSSSDS 305

Query: 404 DAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKR 463
           D+ +V + S  +  D         +   R++EA      +        +  EE+E + +R
Sbjct: 306 DSDEVDRISEWKRRD---------EARRRELEARRRREQEEELRRLREQEKEEKERRRER 356

Query: 464 TFQEEMPPRPCGGHASSSLPKSHLEPSLEEG 494
             + E   R  GG +   L +   EP  + G
Sbjct: 357 ADRGE-AERGSGGSSGDELREDD-EPVKKRG 385


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 53/224 (23%), Positives = 82/224 (36%), Gaps = 19/224 (8%)

Query: 328 SSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYWT 387
           S G    D EE        EE +       P P+         PP    +   + A+   
Sbjct: 67  SGGGPGGDEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPD 126

Query: 388 SSPKPSSYPSTGSSSNDAAQVGKSSR------SRMSDYSPNSTGSVQNTSRDMEASEEGW 441
           +S KP+   +     N   + G   R       R  D +P S         D  A E+G 
Sbjct: 127 ASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGS-----EVPGDKAAEEQGD 181

Query: 442 SQNSRSFRFSRS-SEEREVKEKRTFQEE-----MPPRPCGGHASSSLPKSHLEPSLEEGF 495
            Q+S   + + S  E R VK +R  ++E        R    H+ S  P    E + +E  
Sbjct: 182 DQDSEKSKPAGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEE 241

Query: 496 IDTHCHLDMLYSKLSFQGTFTKF--RKIYSSSFPKEFQGCISDF 537
             T  +LD   S L FQ +  ++  + ++S  FP  + G  S +
Sbjct: 242 DQTLVNLDTYTSDLHFQVSKDRYGGQPLFSEKFPTLWSGARSTY 285


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 55/252 (21%), Positives = 96/252 (38%), Gaps = 28/252 (11%)

Query: 43  ASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCL 102
           + R   P+SP    +   +D+  S R S  ++   +N S + +                +
Sbjct: 32  SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAET----------------V 75

Query: 103 IRNTRGFLSSGGSPLRPANASLEEMASLEEEA---CSLKVDSKDSSHNSTNSEFAAEAEG 159
            ++ +       SPL+      E++AS  EEA    S K  +++ S  ++ SE   E+  
Sbjct: 76  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 135

Query: 160 QNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPS 219
                +E +   K   D  +D  ST   + + Q     S    + +   +A+P A + P+
Sbjct: 136 SRSVNDEGSSDPK---DIDQDNRSTSPSIPSPQDNESDSDSSAQ-QQMLQAQPPALQAPT 191

Query: 220 HGEGPARSEGPAKTAE----GAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRV 275
            G  PA S  P  T +    G   S T    Q    A+   +  +  T P   +   +  
Sbjct: 192 -GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 276 VIDPQEKPSEEP 287
            + PQ  PS  P
Sbjct: 251 ALHPQRPPSPHP 262


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 55/252 (21%), Positives = 96/252 (38%), Gaps = 28/252 (11%)

Query: 43  ASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCL 102
           + R   P+SP    +   +D+  S R S  ++   +N S + +                +
Sbjct: 586 SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAET----------------V 629

Query: 103 IRNTRGFLSSGGSPLRPANASLEEMASLEEEA---CSLKVDSKDSSHNSTNSEFAAEAEG 159
            ++ +       SPL+      E++AS  EEA    S K  +++ S  ++ SE   E+  
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 160 QNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPS 219
                +E +   K   D  +D  ST   + + Q     S    + +   +A+P A + P+
Sbjct: 690 SRSVNDEGSSDPK---DIDQDNRSTSPSIPSPQDNESDSDSSAQ-QQMLQAQPPALQAPT 745

Query: 220 HGEGPARSEGPAKTAE----GAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRV 275
            G  PA S  P  T +    G   S T    Q    A+   +  +  T P   +   +  
Sbjct: 746 -GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 276 VIDPQEKPSEEP 287
            + PQ  PS  P
Sbjct: 805 ALHPQRPPSPHP 816


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 55/252 (21%), Positives = 96/252 (38%), Gaps = 28/252 (11%)

Query: 43  ASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCL 102
           + R   P+SP    +   +D+  S R S  ++   +N S + +                +
Sbjct: 586 SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAET----------------V 629

Query: 103 IRNTRGFLSSGGSPLRPANASLEEMASLEEEA---CSLKVDSKDSSHNSTNSEFAAEAEG 159
            ++ +       SPL+      E++AS  EEA    S K  +++ S  ++ SE   E+  
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 160 QNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHPS 219
                +E +   K   D  +D  ST   + + Q     S    + +   +A+P A + P+
Sbjct: 690 SRSVNDEGSSDPK---DIDQDNRSTSPSIPSPQDNESDSDSSAQ-QQMLQAQPPALQAPT 745

Query: 220 HGEGPARSEGPAKTAE----GAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRV 275
            G  PA S  P  T +    G   S T    Q    A+   +  +  T P   +   +  
Sbjct: 746 -GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 276 VIDPQEKPSEEP 287
            + PQ  PS  P
Sbjct: 805 ALHPQRPPSPHP 816


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 30/113 (26%), Positives = 47/113 (41%)

Query: 387 TSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSR 446
           +SS  PSS PS+   S   +Q G S R+R+   S +    V          EE       
Sbjct: 647 SSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVKPEESRDITRP 706

Query: 447 SFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTH 499
           S     ++  +E++E R  +   P +    ++SSS      E   E+G  +TH
Sbjct: 707 SRPADLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESETH 759


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 30/113 (26%), Positives = 47/113 (41%)

Query: 387 TSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSR 446
           +SS  PSS PS+   S   +Q G S R+R+   S +    V          EE       
Sbjct: 676 SSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVKPEESRDITRP 735

Query: 447 SFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTH 499
           S     ++  +E++E R  +   P +    ++SSS      E   E+G  +TH
Sbjct: 736 SRPADLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESETH 788


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 30/113 (26%), Positives = 47/113 (41%)

Query: 387 TSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSR 446
           +SS  PSS PS+   S   +Q G S R+R+   S +    V          EE       
Sbjct: 702 SSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVKPEESRDITRP 761

Query: 447 SFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTH 499
           S     ++  +E++E R  +   P +    ++SSS      E   E+G  +TH
Sbjct: 762 SRPADLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESETH 814


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 30/113 (26%), Positives = 47/113 (41%)

Query: 387 TSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQNSR 446
           +SS  PSS PS+   S   +Q G S R+R+   S +    V          EE       
Sbjct: 731 SSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVKPEESRDITRP 790

Query: 447 SFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTH 499
           S     ++  +E++E R  +   P +    ++SSS      E   E+G  +TH
Sbjct: 791 SRPADLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESETH 843


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 40/155 (25%), Positives = 58/155 (37%), Gaps = 29/155 (18%)

Query: 145 SHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTM-----------IYLKAIQG 193
           S  +   E AAE  G+      P+K   ++   ++  G              +       
Sbjct: 6   SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65

Query: 194 ILGKSMPKRKGE------AATRAKPSAAEHPSHGEGPARSEGPAK----------TAEG- 236
              K  P   G       AA + +P+AA  P  G  P   E PA+           AEG 
Sbjct: 66  AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125

Query: 237 AARSVTVTAAQKEKD-ATPEVSMEEDKTVPERSSF 270
           AA + + T++ K +D ATP  S E  K   +R SF
Sbjct: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSF 160


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 61/314 (19%), Positives = 117/314 (37%), Gaps = 41/314 (13%)

Query: 5   RGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSR---PAQRSASRSGGPSSPKRLKAQKED 61
           +  VK    S +E    ++   + P +V    +   PA+  A       SP++ +A+   
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA 576

Query: 62  DVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRP-A 120
           +V    +    +     + + + SP                            SP++  A
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPE------------------------KAKSPVKEEA 612

Query: 121 NASLEEMASLEEEACS-LKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRD--- 176
            +  E  + ++EEA S  +V S + + + T  E  +  + ++   EE    +K K     
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672

Query: 177 --RLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEH---PSHGEGPARSEGPA 231
             +  ++  + +  +A      KS  K + ++  +AK    E    P   + P + E  A
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE--A 730

Query: 232 KTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERS--SFYDRRVVIDPQEKPSEEPLG 289
           KT E A   V   A   EK  +PE +   D   PE    +  + R   D   + ++ P+ 
Sbjct: 731 KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790

Query: 290 DRRTVIDKCSPPLE 303
           +     +K   PL+
Sbjct: 791 EEVKSPEKAKSPLK 804


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 94/451 (20%), Positives = 156/451 (34%), Gaps = 43/451 (9%)

Query: 44   SRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGG-----AAS 98
            +R+ G   PK + +  +D +        G      N S       +    GG     A+ 
Sbjct: 584  ARTKGTEKPKDIGSSSKDHLQ-------GLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636

Query: 99   KGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAE 158
              C   N +    S GS       SL        ++   K   K    +    +  A+ E
Sbjct: 637  SACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696

Query: 159  GQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRAKPSAAEHP 218
             ++   E   K +KRK+ R R +  +     + +G   K  P   G  A   +   A+  
Sbjct: 697  EKSSKAESGEKSKKRKK-RKRKKNKSSAPADSERG--PKPEPPGSGSPAPPRRRRRAQDD 753

Query: 219  SHGEGPARSEGPA--KTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVV 276
            S        EG +  K   G   S      +K K   P  S +  +   +RSS    R  
Sbjct: 754  SQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQR-RAGTKRSSRSSHRSQ 812

Query: 277  IDPQEKPSEEPLGDRRTVIDKCSPPL----EFLDDSDSHLEIQKHKDREVVMEHPSSGSD 332
                ++ S++    R   + + SP      E  +DS S     + +       H SS   
Sbjct: 813  PSSGDEDSDDASSHR---LHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRS 869

Query: 333  WSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASY------- 385
            +S   + S+ +       S    +    S ++     +    + S   DYAS        
Sbjct: 870  YSSSSDASSDQSCYSRQRSYSDDSY---SDYSDRSRRHSKRSHDSDDSDYASSKHRSKRH 926

Query: 386  -WTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYSPNSTGSVQNTSRDMEASEEGWSQN 444
             ++SS    S   + S S   +   + SRSR    S + + S ++  R    +   W Q 
Sbjct: 927  KYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS-RSKRRSRSTTAHSW-QR 984

Query: 445  SRSF-----RFSRSSEEREVKEKRTFQEEMP 470
            SRS+     R +RS  +R    KR++  E P
Sbjct: 985  SRSYSRDRSRSTRSPSQRSGSRKRSWGHESP 1015



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 21/161 (13%)

Query: 21  RKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNS 80
           RK++    P D   S R  +     SG P+ P+R +  ++D    S     GSS +++  
Sbjct: 716 RKKNKSSAPAD---SERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDE- 771

Query: 81  SSSFSPHFLGPGVGGAASKGCLIRNTRGFLSSGGSPLRPANASLEEMASLEEEACSLKVD 140
                      G GG++S+    R  +G L    S  R A       +S   +  S   D
Sbjct: 772 -----------GGGGSSSQDHGGRKHKGELPP-SSCQRRAGTKRSSRSSHRSQPSSGDED 819

Query: 141 SKDSS----HNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDR 177
           S D+S    H  + S+++ E E + D+  E ++ + R   R
Sbjct: 820 SDDASSHRLHQKSPSQYSEEEE-EEDSGSEHSRSRSRSGRR 859


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,058,312
Number of Sequences: 37866
Number of extensions: 1680710
Number of successful extensions: 6728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 187
Number of HSP's that attempted gapping in prelim test: 6199
Number of HSP's gapped (non-prelim): 674
length of query: 761
length of database: 18,247,518
effective HSP length: 110
effective length of query: 651
effective length of database: 14,082,258
effective search space: 9167549958
effective search space used: 9167549958
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.