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Search of human proteins with 225903367
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225903367 glycine receptor, alpha 1 isoform 1 precursor
[Homo sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 931 0.0
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 908 0.0
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 754 0.0
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 753 0.0
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 698 0.0
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 696 0.0
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 696 0.0
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 615 e-176
gi|4504023 glycine receptor, beta [Homo sapiens] 355 5e-98
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 289 4e-78
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 288 5e-78
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 288 7e-78
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 288 9e-78
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 283 3e-76
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 280 1e-75
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 280 3e-75
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 280 3e-75
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 280 3e-75
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom... 275 6e-74
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 272 5e-73
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 271 1e-72
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 271 1e-72
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 271 1e-72
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 271 1e-72
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 271 1e-72
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 271 1e-72
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 271 1e-72
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 271 1e-72
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 270 2e-72
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 269 3e-72
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 931 bits (2407), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF
Sbjct: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
Query: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
Query: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF 360
SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF
Sbjct: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF 360
Query: 361 QEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA 420
QEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA
Sbjct: 361 QEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA 420
Query: 421 KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
Sbjct: 421 KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 908 bits (2347), Expect = 0.0
Identities = 449/457 (98%), Positives = 449/457 (98%), Gaps = 8/457 (1%)
Query: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF
Sbjct: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
Query: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
Query: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF 360
SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHK
Sbjct: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHK------- 353
Query: 361 QEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA 420
EDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA
Sbjct: 354 -EDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA 412
Query: 421 KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
Sbjct: 413 KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 449
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 754 bits (1947), Expect = 0.0
Identities = 369/448 (82%), Positives = 402/448 (89%), Gaps = 15/448 (3%)
Query: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Query: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
Query: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
Query: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
Query: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
Query: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGR 369
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR++ ++DE E R
Sbjct: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKN---------KDDEVRESR 365
Query: 370 FNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRI 429
F+F+AYGMGP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKID ISR
Sbjct: 366 FSFTAYGMGP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKIDTISRA 419
Query: 430 GFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
FP+AFLIFN+FYW+IYKI+R ED+H Q
Sbjct: 420 CFPLAFLIFNIFYWVIYKILRHEDIHQQ 447
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 753 bits (1943), Expect = 0.0
Identities = 371/454 (81%), Positives = 403/454 (88%), Gaps = 12/454 (2%)
Query: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Query: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
Query: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
Query: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
Query: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
Query: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPM-LNLF-----QED 363
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR++ L F +D
Sbjct: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDD 374
Query: 364 EAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKI 423
E E RF+F+AYGMGP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKI
Sbjct: 375 EVRESRFSFTAYGMGP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKI 428
Query: 424 DKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
D ISR FP+AFLIFN+FYW+IYKI+R ED+H Q
Sbjct: 429 DTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQ 462
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 698 bits (1802), Expect = 0.0
Identities = 341/433 (78%), Positives = 375/433 (86%), Gaps = 11/433 (2%)
Query: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGSIAETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
Query: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 325 ALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQA 384
ALLEYAAVNFVSRQHKE LR RR+++ +ED E RFNFS YGMG CLQ
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNK------EEDVTRESRFNFSGYGMG-HCLQV 383
Query: 385 KDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWI 444
KDG +VK + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI
Sbjct: 384 KDGTAVK----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
Query: 445 IYKIVRREDVHNQ 457
YKI+R EDVH +
Sbjct: 440 TYKIIRHEDVHKK 452
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 696 bits (1797), Expect = 0.0
Identities = 339/433 (78%), Positives = 374/433 (86%), Gaps = 11/433 (2%)
Query: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 325 ALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQA 384
ALLEYAAVNFVSRQHKE LR RR+++ +ED E RFNFS YGMG CLQ
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNK------EEDVTRESRFNFSGYGMG-HCLQV 383
Query: 385 KDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWI 444
KDG +VK + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI
Sbjct: 384 KDGTAVK----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
Query: 445 IYKIVRREDVHNQ 457
YKI+R EDVH +
Sbjct: 440 TYKIIRHEDVHKK 452
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 696 bits (1797), Expect = 0.0
Identities = 339/433 (78%), Positives = 374/433 (86%), Gaps = 11/433 (2%)
Query: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 325 ALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQA 384
ALLEYAAVNFVSRQHKE LR RR+++ +ED E RFNFS YGMG CLQ
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNK------EEDVTRESRFNFSGYGMG-HCLQV 383
Query: 385 KDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWI 444
KDG +VK + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI
Sbjct: 384 KDGTAVK----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
Query: 445 IYKIVRREDVHNQ 457
YKI+R EDVH +
Sbjct: 440 TYKIIRHEDVHKK 452
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 615 bits (1586), Expect = e-176
Identities = 307/399 (76%), Positives = 342/399 (85%), Gaps = 13/399 (3%)
Query: 22 ASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAE 81
A +E ++ +PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSF SI +
Sbjct: 28 AKEEVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFSSITK 87
Query: 82 TTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITT 141
TTMDYRVN+FLRQQWNDPRL+Y EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FHE+TT
Sbjct: 88 TTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTT 147
Query: 142 DNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQ 201
DNKLLRI +NGNVLYSIR+TL L+C MDLKNFPMD+QTC MQLESFGYTM DL+FEW E
Sbjct: 148 DNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLVFEWLED 207
Query: 202 G-AVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSL 260
AVQVA+GLTLPQFIL++EKDL CTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSL
Sbjct: 208 APAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSL 267
Query: 261 LIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL 320
LIVILSW+SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL
Sbjct: 268 LIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL 327
Query: 321 FVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPA 380
FVF+ALLEYAA+NFVSRQHKE +R RR++R + +ED E RF F YG+G
Sbjct: 328 FVFAALLEYAAINFVSRQHKEFIRLRRRQRRQR------LEEDIIQESRFYFRGYGLG-H 380
Query: 381 CLQAKDGISVKGANNSNTTNP-PPAP-SKSPEEMRKLFI 417
CLQA+DG ++G S +P PPAP + E RKL++
Sbjct: 381 CLQARDGGPMEG---SGIYSPQPPAPLLREGETTRKLYV 416
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 355 bits (911), Expect = 5e-98
Identities = 208/459 (45%), Positives = 277/459 (60%), Gaps = 66/459 (14%)
Query: 37 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQW 96
S S+ L++L+ YD RIRPNFKG PV+V NIFINSFGSI ETTMDYRVNIFLRQ+W
Sbjct: 55 STSNILNRLL---VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKW 111
Query: 97 NDPRLAYNE--YPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNV 154
NDPRL D+L +DP+M +WKPDLFFANEK A+FH++T +N LL I R+G+V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 155 LYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQ 214
L S+R+++TL+CP+DL FPMD Q C MQLESFGYT +DL F WQ VQ+ + + LPQ
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQ 230
Query: 215 FILKEEKDLRY--CTKHYN-TGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFW 271
F +K+E D+ Y CTK+Y TG +TC+E F L RQ+G+Y++ +Y P+LLIV+LSW+SFW
Sbjct: 231 FDIKKE-DIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFW 289
Query: 272 INMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAA 331
IN DA+ ARV LGI +VL++ ++ + A LPKVSYVKA+D+W+ CLLF F++L+EYA
Sbjct: 290 INPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAV 349
Query: 332 VNFVSRQHKELLRFRRKRRHHKSPML-----NLFQED--------------EAGEGR--- 369
V + K + K R K+ N+ +++ + GE R
Sbjct: 350 VQVMLNNPKRV--EAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKK 407
Query: 370 ----------------------FNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSK 407
F S Y ++ +G+ A N+ PPPA
Sbjct: 408 VCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNK--KPPPAKPV 465
Query: 408 SPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
P AK+ID +R FP FL FN+ YW IY
Sbjct: 466 IP--------TAAKRIDLYARALFPFCFLFFNVIYWSIY 496
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 289 bits (739), Expect = 4e-78
Identities = 177/458 (38%), Positives = 255/458 (55%), Gaps = 43/458 (9%)
Query: 26 AEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMD 85
A A+S P + S + + GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 21 AVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
Query: 86 YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKL 145
Y + ++ +Q W D RL+YN P + L LD + D +W PD +F N+K + H +T N++
Sbjct: 81 YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
Query: 146 LRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAV 204
+R+ +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ + AV
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
Query: 205 QVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLI 262
+ LPQF + D + TK ++TG + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
Query: 263 VILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 322
ILSW+SFWIN DA+ ARV LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
Query: 323 FSALLEYAAVNFV------SRQHK----------ELLRFR-RKRRHHKSPML------NL 359
F ALLEYA VN++ RQ K E +R K H++ +L N
Sbjct: 317 FMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNE 376
Query: 360 FQEDEA----GEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMR-- 413
EA G+ R AY + +Q + + + N A KS R
Sbjct: 377 MATSEAVMGLGDPRSTMLAY--DASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRAS 434
Query: 414 --KLFI---QRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
K+ I ID+ SRI FP+ F FN+ YW+ Y
Sbjct: 435 QLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 288 bits (738), Expect = 5e-78
Identities = 169/451 (37%), Positives = 250/451 (55%), Gaps = 36/451 (7%)
Query: 29 ARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRV 88
A S +P + S + + GYD R+RP+F GPPV+V I + S ++E MDY +
Sbjct: 25 AHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTL 84
Query: 89 NIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRI 148
++ +Q W D RL+Y+ P + L LD + D +W PD +F N+K + H +T N+++R+
Sbjct: 85 TMYFQQSWKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRL 143
Query: 149 SRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVA 207
+G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W +GAV
Sbjct: 144 HPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGV 203
Query: 208 DGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSW 267
+ + LPQF + + K + + + TG + + F L+R +GY+++Q Y+PS LI ILSW
Sbjct: 204 NKIELPQFSIVDYKMVSKKVE-FTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSW 262
Query: 268 ISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALL 327
+SFWIN DA+ ARV LGITTVLTMTT S+ R +LPK+ YVKAIDI++ C +FVF ALL
Sbjct: 263 VSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALL 322
Query: 328 EYAAVNFV----SRQHKELLRFRRKRRHHKSPMLNLFQEDEAG-------EGRFNFSA-- 374
EYA VN++ Q K + + +N Q D G E R S
Sbjct: 323 EYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSE 382
Query: 375 ------------YGMGPACLQAKDGISVKGANNSNTTNPPPAPSK-------SPEEMRKL 415
Y A +Q + +S + A + PSK S +++
Sbjct: 383 VLTSVSDPKATMYSYDSASIQYRKPLSSREA-YGRALDRHGVPSKGRIRRRASQLKVKIP 441
Query: 416 FIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
+ IDK SR+ FP+ F +FN+ YW+ Y
Sbjct: 442 DLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 288 bits (737), Expect = 7e-78
Identities = 172/466 (36%), Positives = 254/466 (54%), Gaps = 41/466 (8%)
Query: 16 VFFSLAASKEAEAARSAPKPMSPS---DFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIF 72
++ S RS P + S + +DKL+ GYD R+RP+F GPPV V NI
Sbjct: 12 IWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLL---KGYDIRLRPDFGGPPVCVGMNID 68
Query: 73 INSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEK 132
I S ++E MDY + ++ +Q W D RLAY+ P + L LD + D +W PD +F N+K
Sbjct: 69 IASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDK 127
Query: 133 GAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMN 192
+ H +T N+++R+ +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +
Sbjct: 128 KSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 187
Query: 193 DLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYY 251
D+ F W+ AV + + LPQF + E + L + TG + + F L+R +GY+
Sbjct: 188 DIEFYWRGGDKAVTGVERIELPQFSIVEHR-LVSRNVVFATGAYPRLSLSFRLKRNIGYF 246
Query: 252 LIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAI 311
++Q Y+PS+LI ILSW+SFWIN DA+ ARV LGITTVLTMTT ++ R +LPK+ YVKAI
Sbjct: 247 ILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAI 306
Query: 312 DIWMAVCLLFVFSALLEYAAVNFV-----SRQHKELLRFRRKRRHHKS------------ 354
D+++ C +FVF ALLEYA VN++ ++ K+L K ++ +S
Sbjct: 307 DMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGN 366
Query: 355 ------PMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKS 408
+ N E G G SA + +Q + S+ + P K
Sbjct: 367 ILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQ-SMPREGHGRFLGDRSLPHKK 425
Query: 409 PEEMRKLFIQRAK--------KIDKISRIGFPMAFLIFNMFYWIIY 446
R+ + K ID+ SRI FP F +FN+ YW+ Y
Sbjct: 426 THLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 288 bits (736), Expect = 9e-78
Identities = 167/437 (38%), Positives = 245/437 (56%), Gaps = 38/437 (8%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
+DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL
Sbjct: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
AY+ P +L LD + D +W PD +F N+K + H +T N+++R+ +G VLY +RIT
Sbjct: 98 AYSGIP-LNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAVQVADGLTLPQFILKEE 220
T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ AV + + LPQF + E
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 221 KDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPAR 280
+ L + TG + + F L+R +GY+++Q Y+PS+LI ILSW+SFWIN DA+ AR
Sbjct: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275
Query: 281 VGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV----- 335
V LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++
Sbjct: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335
Query: 336 SRQHKELLRFRRKRRHHKS------------------PMLNLFQEDEAGEGRFNFSAYGM 377
++ K+L K ++ +S + N E G G SA
Sbjct: 336 PQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISF 395
Query: 378 GPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAK--------KIDKISRI 429
+ +Q + S+ + P K R+ + K ID+ SRI
Sbjct: 396 DNSGIQYRKQ-SMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRI 454
Query: 430 GFPMAFLIFNMFYWIIY 446
FP F +FN+ YW+ Y
Sbjct: 455 VFPFTFSLFNLVYWLYY 471
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 283 bits (723), Expect = 3e-76
Identities = 158/412 (38%), Positives = 227/412 (55%), Gaps = 7/412 (1%)
Query: 41 FLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPR 100
+L L G +GY RP GPPVNV+ + + S I+E M+Y + +FL Q W D R
Sbjct: 40 WLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSR 99
Query: 101 LAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRI 160
L+YN + +++L LD +D +W PD F N K A FH++T +NKL+R+ +G +LYSIRI
Sbjct: 100 LSYN-HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRI 158
Query: 161 TLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKE 219
T T+AC MDL +PMD Q C++ LES+GY+ D+++ W E Q + D L L QF +
Sbjct: 159 TSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITS 218
Query: 220 EKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA 279
+ + G+F + FHL R G Y+IQ Y+PS+L+V +SW+SFWI+ A PA
Sbjct: 219 YRFTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPA 278
Query: 280 RVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNF-VSRQ 338
RV LGITTVLTMTT +R+SLP+ S +KA+D++ +C +FVF+AL+EYA +F +
Sbjct: 279 RVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYR 338
Query: 339 HKELLRFRRKRRHHKSPMLN---LFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANN 395
K+ + + R + + N LF AG + + G
Sbjct: 339 KKQKAKVKVSRPRAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVET 398
Query: 396 SNTTNPPPAPSKSPEEMR-KLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
T A S +R +L A ID +R FP AF N+ YW Y
Sbjct: 399 GETKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 280 bits (717), Expect = 1e-75
Identities = 141/313 (45%), Positives = 204/313 (65%), Gaps = 7/313 (2%)
Query: 26 AEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMD 85
A A+S P + S + + GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 21 AVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
Query: 86 YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKL 145
Y + ++ +Q W D RL+YN P + L LD + D +W PD +F N+K + H +T N++
Sbjct: 81 YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
Query: 146 LRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAV 204
+R+ +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ + AV
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
Query: 205 QVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLI 262
+ LPQF + D + TK ++TG + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
Query: 263 VILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 322
ILSW+SFWIN DA+ ARV LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
Query: 323 FSALLEYAAVNFV 335
F ALLEYA VN++
Sbjct: 317 FMALLEYALVNYI 329
Score = 33.5 bits (75), Expect = 0.41
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 423 IDKISRIGFPMAFLIFNMFYWIIY 446
ID+ SRI FP+ F FN+ YW+ Y
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 280 bits (715), Expect = 3e-75
Identities = 162/424 (38%), Positives = 245/424 (57%), Gaps = 34/424 (8%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P + L L+ M IW PD FF N K + H +T NKLLRI +G +LY++R+T
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QEQGAVQVA-DGLTLPQFILK 218
+ CPM L++FPMD +C ++ S+ YT +++ + W +VQVA DG L Q+ L
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
+ + K +TG++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 222 GQSIGKETIKS-STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
Query: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Query: 339 -----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQ---AKDGISV 390
K ++ ++K E +AY + A +KD +
Sbjct: 341 GWAWDGKSVVNDKKK---------------EKASVMIQNNAYAVAVANYAPNLSKDPVLS 385
Query: 391 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 450
+ ++ T P P P E +K F KID++SRI FP+ F FN+ YW Y +
Sbjct: 386 TISKSATTPEPNKKPENKPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY--LN 442
Query: 451 REDV 454
RE V
Sbjct: 443 REPV 446
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 280 bits (715), Expect = 3e-75
Identities = 162/424 (38%), Positives = 245/424 (57%), Gaps = 34/424 (8%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P + L L+ M IW PD FF N K + H +T NKLLRI +G +LY++R+T
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QEQGAVQVA-DGLTLPQFILK 218
+ CPM L++FPMD +C ++ S+ YT +++ + W +VQVA DG L Q+ L
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
+ + K +TG++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 222 GQSIGKETIKS-STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
Query: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Query: 339 -----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQ---AKDGISV 390
K ++ ++K E +AY + A +KD +
Sbjct: 341 GWAWDGKSVVNDKKK---------------EKASVMIQNNAYAVAVANYAPNLSKDPVLS 385
Query: 391 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 450
+ ++ T P P P E +K F KID++SRI FP+ F FN+ YW Y +
Sbjct: 386 TISKSATTPEPNKKPENKPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY--LN 442
Query: 451 REDV 454
RE V
Sbjct: 443 REPV 446
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 280 bits (715), Expect = 3e-75
Identities = 161/416 (38%), Positives = 234/416 (56%), Gaps = 16/416 (3%)
Query: 39 SDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWND 98
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
Query: 99 PRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSI 158
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
Query: 159 RITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF 215
R+T+ CPM L NFPMD C ++ S+ Y +++I+ W++ V + +L Q+
Sbjct: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQY 208
Query: 216 ILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMD 275
L + K NTG++ + FHL+R+MGY++IQ+Y P ++ VILS +SFWIN +
Sbjct: 209 DLIGQTVSSETIKS-NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Query: 276 AAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 335
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
Query: 336 SRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNF---SAYGMGPACLQAKDGISVKG 392
+ + + +RK + P + + + E E S Y + I
Sbjct: 328 TNLQTQ--KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSS 385
Query: 393 ANNSNTTNPPPAPSK--SPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
N T P S +P + F KID+ SRI FP+AF FN+ YW++Y
Sbjct: 386 EANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
sapiens]
Length = 479
Score = 275 bits (703), Expect = 6e-74
Identities = 151/421 (35%), Positives = 243/421 (57%), Gaps = 9/421 (2%)
Query: 30 RSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVN 89
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
Query: 90 IFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRIS 149
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
Query: 150 RNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVAD 208
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W++ +++ +
Sbjct: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
Query: 209 GLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWI 268
++L QF+++E + +TG + + F L R + ++L+Q Y P+ L+V+LSW+
Sbjct: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
Query: 269 SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 328
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
Query: 329 YAAVNF---VSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAK 385
YAAVN+ V + ++ LR + P + +G N M P +
Sbjct: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYM-PENGEKP 420
Query: 386 DGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWII 445
D + V+ S ++P +S ++ IDK SRI FP A+++FN+ YW I
Sbjct: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRI---DTHAIDKYSRIIFPAAYILFNLIYWSI 477
Query: 446 Y 446
+
Sbjct: 478 F 478
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 272 bits (695), Expect = 5e-73
Identities = 151/410 (36%), Positives = 238/410 (58%), Gaps = 16/410 (3%)
Query: 48 RTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP 107
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA++
Sbjct: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
Query: 108 DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACP 167
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+ +G+VLYS+RIT+T C
Sbjct: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
Query: 168 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYC 226
MD +FP+D QTC ++LES+ YT DL+ W+ +++ + ++L QF++++
Sbjct: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
Query: 227 TKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGIT 286
+ +TG + + F L R + ++L+Q Y P+ L+V+LSW+SFWI+ A PARV LGIT
Sbjct: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
Query: 287 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR-QHKELLRF 345
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ Q ++ +
Sbjct: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
Query: 346 RRK------RRHHKSPMLN-LFQEDEAGEGRFNFSAYGMGPACL--QAKDGISVKGANNS 396
R K H K+ ML+ + E EA + + Y + +D I V S
Sbjct: 385 REKFPCMCGMLHSKTMMLDGSYSESEAN----SLAGYPRSHILTEEERQDKIVVH-LGLS 439
Query: 397 NTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
N + Q IDK SR+ FP +++ FN+ YW ++
Sbjct: 440 GEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 271 bits (692), Expect = 1e-72
Identities = 155/423 (36%), Positives = 235/423 (55%), Gaps = 34/423 (8%)
Query: 45 LMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYN 104
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
Query: 105 EYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTL 164
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++R+T++
Sbjct: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
Query: 165 ACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE---QGAVQVADGLTLPQFILKEEK 221
CPM L++FPMD C ++ S+ Y +++++ W + V DG L Q+ L +
Sbjct: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 222 DLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA 279
T++ +T G++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ PA
Sbjct: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
Query: 280 RVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--- 336
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
Query: 337 -----RQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVK 391
++ E + ++KR + N F + P + +
Sbjct: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSH-----------PPNIPKEQ----T 393
Query: 392 GANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRR 451
A SNTT+ PS+ K KIDK+SRI FP+ F FN+ YW Y + R
Sbjct: 394 PAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY--LNR 451
Query: 452 EDV 454
E V
Sbjct: 452 EPV 454
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 271 bits (692), Expect = 1e-72
Identities = 156/415 (37%), Positives = 235/415 (56%), Gaps = 28/415 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKG 392
+ K ++ K + K P++ + +A P + G++
Sbjct: 340 RGYAWDGKSVV--PEKPKKVKDPLIK-------KNNTYAPTATSYTPNLARGDPGLAT-- 388
Query: 393 ANNSNTTNPPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
S T P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 270 bits (690), Expect = 2e-72
Identities = 145/405 (35%), Positives = 233/405 (57%), Gaps = 19/405 (4%)
Query: 49 TSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD 108
T+GY+ +RPNF G PV ++ + I S SI+E+ MDY I+LRQ+W D RL + +
Sbjct: 45 TAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--N 102
Query: 109 DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPM 168
S LD +++ +W PD + K + HE+T N+L+R+ NG VLY++RIT T+AC M
Sbjct: 103 KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNM 162
Query: 169 DLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QEQGAVQVADGLTLPQFILKEEKDLRYCT 227
DL +PMD QTC +QLES+GY ND+ F W + +V+ + L L Q+ ++ RY T
Sbjct: 163 DLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIE-----RYFT 217
Query: 228 ----KHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGL 283
TG +T + +F L R + Y++++ Y+PS +V+LSW+SFWI++D+ PAR +
Sbjct: 218 LVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCI 277
Query: 284 GITTVLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKEL 342
G+TTVL+MTT GSR SLP + ++KAID+++ +C FVF ALLEYA ++ S Q
Sbjct: 278 GVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAA 337
Query: 343 LRFRRKRRHHKSPMLNLFQED-EAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNP 401
+ + + N+ + + + +F++ + + D +++K ++
Sbjct: 338 KDRGTTKEVEEVSITNIINSSISSFKRKISFASIEISSDNVDYSD-LTMKTSDKFKFV-- 394
Query: 402 PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
K + IQ +D S++ FP+ F++ N+FYW Y
Sbjct: 395 --FREKMGRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 269 bits (688), Expect = 3e-72
Identities = 161/422 (38%), Positives = 236/422 (55%), Gaps = 21/422 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
++ P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++R+T
Sbjct: 128 KFDG-PMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--EQGAVQVA-DGLTLPQFILK 218
+ CPM L++FPMDV C ++ S+ YT ++++ W + +V+VA DG L Q+ L
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
+ +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 247 GHVVGTEIIRS-STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
Query: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT-- 363
Query: 339 HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKD---GISVKGANN 395
K + K+ M A + F+ G AKD KGA
Sbjct: 364 -KRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAP 422
Query: 396 SNTTNP-----PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 450
S ++ P P A K+DKISRI FP+ F IFN+ YW Y V
Sbjct: 423 SASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY--VN 480
Query: 451 RE 452
RE
Sbjct: 481 RE 482
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,567,078
Number of Sequences: 37866
Number of extensions: 780187
Number of successful extensions: 3142
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 2929
Number of HSP's gapped (non-prelim): 107
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.