Guide to the Human Genome
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Search of human proteins with 22547219

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22547219 Toll-interleukin 1 receptor domain-containing
adaptor protein isoform b [Homo sapiens]
         (235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22547219 Toll-interleukin 1 receptor domain-containing adapto...   479   e-136
gi|89111122 Toll-interleukin 1 receptor domain-containing adapto...   441   e-124
gi|197276654 myeloid differentiation primary response gene 88 [H...    52   3e-07
gi|19718734 toll-like receptor 2 [Homo sapiens]                        49   5e-06
gi|20143971 toll-like receptor 6 [Homo sapiens]                        43   3e-04
gi|41281981 toll-like receptor adaptor molecule 1 [Homo sapiens]       39   0.005
gi|41350337 toll-like receptor 1 [Homo sapiens]                        37   0.015
gi|62865621 toll-like receptor 10 precursor [Homo sapiens]             37   0.015
gi|62865618 toll-like receptor 10 precursor [Homo sapiens]             37   0.015
gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isofor...    37   0.015
gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isofor...    37   0.015
gi|16751843 toll-like receptor 5 [Homo sapiens]                        37   0.019
gi|67906195 ankyrin repeat and sterile alpha motif domain contai...    36   0.025
gi|34996489 pleckstrin homology domain interacting protein [Homo...    36   0.033
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    34   0.12 
gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]        34   0.12 
gi|116284392 mucin 2 precursor [Homo sapiens]                          33   0.16 
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             33   0.16 
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1...    33   0.16 
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  33   0.16 
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]          33   0.21 
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas...    33   0.21 
gi|148613878 acrosin precursor [Homo sapiens]                          33   0.21 
gi|223633988 hypothetical protein LOC85379 [Homo sapiens]              33   0.28 
gi|33386674 toll-like receptor adaptor molecule 2 [Homo sapiens]       33   0.28 
gi|21735550 mitogen-activated protein kinase kinase kinase 10 [H...    33   0.28 
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso...    32   0.36 
gi|79749430 FRAS1-related extracellular matrix protein 2 precurs...    32   0.36 
gi|169164209 PREDICTED: hypothetical protein [Homo sapiens]            32   0.47 
gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo ...    32   0.47 

>gi|22547219 Toll-interleukin 1 receptor domain-containing adaptor
           protein isoform b [Homo sapiens]
          Length = 235

 Score =  479 bits (1233), Expect = e-136
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60
           MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS
Sbjct: 1   MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60

Query: 61  LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120
           LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL
Sbjct: 61  LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120

Query: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180
           RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS
Sbjct: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180

Query: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRCKLLQEGEGERDSATVSDLL 235
           GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRCKLLQEGEGERDSATVSDLL
Sbjct: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRCKLLQEGEGERDSATVSDLL 235


>gi|89111122 Toll-interleukin 1 receptor domain-containing adaptor
           protein isoform a [Homo sapiens]
          Length = 221

 Score =  441 bits (1133), Expect = e-124
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60
           MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS
Sbjct: 1   MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60

Query: 61  LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120
           LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL
Sbjct: 61  LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120

Query: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180
           RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS
Sbjct: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180

Query: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMR 215
           GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMR
Sbjct: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMR 215


>gi|197276654 myeloid differentiation primary response gene 88 [Homo
           sapiens]
          Length = 309

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 43/178 (24%), Positives = 81/178 (45%), Gaps = 19/178 (10%)

Query: 29  LLKKPKKRPNSPESTSS-DASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYD 87
           +LK+ ++    P   ++ D+S P + +      L+ +T+   P  H  +         +D
Sbjct: 130 ILKQQQEEAEKPLQVAAVDSSVPRTAE------LAGITTLDDPLGHMPER--------FD 175

Query: 88  VCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCR--VL 145
             +C+   D+   Q+++  LE +   L+  +  RD  PG  + S +   L    CR  V+
Sbjct: 176 AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWS-IASELIEKRCRRMVV 234

Query: 146 LITPGFLQDPWCKYQMLQALTEAPGA-EGCTIPLLSGLSRAAYPPELRFMYYVDGRGP 202
           +++  +LQ   C +Q   AL+ +PGA +   IP+     +  +P  LRF+   D   P
Sbjct: 235 VVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNP 292


>gi|19718734 toll-like receptor 2 [Homo sapiens]
          Length = 784

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 1/77 (1%)

Query: 86  YDVCVCHSEEDLVAAQDL-VSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRV 144
           YD  V +SE D    ++L V  LE      +  L  RD  PG  I+  +  ++  SH  V
Sbjct: 641 YDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTV 700

Query: 145 LLITPGFLQDPWCKYQM 161
            +++  F++  WCKY++
Sbjct: 701 FVLSENFVKSEWCKYEL 717


>gi|20143971 toll-like receptor 6 [Homo sapiens]
          Length = 796

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)

Query: 90  VCHSEEDLV-AAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT 148
           + +SE D      +LV YLE     ++  L  R+  PG +IV  +   +  S+  + +++
Sbjct: 646 ISYSEHDSAWVKSELVPYLEKE--DIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLS 703

Query: 149 PGFLQDPWCKYQM 161
           P F+Q  WC Y++
Sbjct: 704 PNFVQSEWCHYEL 716


>gi|41281981 toll-like receptor adaptor molecule 1 [Homo sapiens]
          Length = 712

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 49/183 (26%), Positives = 66/183 (36%), Gaps = 6/183 (3%)

Query: 2   ASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSL 61
           A   SLP P   P K    + D     L  +    PN+     +  +  TS   P PP  
Sbjct: 309 AGPQSLPLPILEPVKNPCSVKDQTPLQLSVEDTTSPNTKPCPPTPTTPETSPPPPPPPPS 368

Query: 62  SSVTSPSLPPTHASDSG--SSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQ 119
           S+  S  L P+    S   SS   K Y+  + H+  D   A  +   LE           
Sbjct: 369 STPCSAHLTPSSLFPSSLESSSEQKFYNFVILHARADEHIALRVREKLEALGVPDGATFC 428

Query: 120 LRDATPGGAIVSELCQALSSSHCRVLLITPGF---LQDPWCKYQMLQALTEAPGAEGCTI 176
                PG   +S L  A+  S   +LL+T  F   L        M+  LT   G+  C I
Sbjct: 429 EDFQVPGRGELSCLQDAIDHSAFIILLLTSNFDCRLSLHQVNQAMMSNLTR-QGSPDCVI 487

Query: 177 PLL 179
           P L
Sbjct: 488 PFL 490


>gi|41350337 toll-like receptor 1 [Homo sapiens]
          Length = 786

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 13/44 (29%), Positives = 25/44 (56%)

Query: 118 LQLRDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQM 161
           L  R+  PG +IV  +   +  S+  + +++P F+Q  WC Y++
Sbjct: 668 LHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYEL 711


>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
          Length = 811

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 90  VCHSEED-LVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT 148
           + +SE D L    +L+  LE    S+   L      PG +I   +   +  S+  + +++
Sbjct: 638 ISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLS 697

Query: 149 PGFLQDPWCKYQ 160
           P F+Q+ WC Y+
Sbjct: 698 PNFVQNEWCHYE 709


>gi|62865618 toll-like receptor 10 precursor [Homo sapiens]
          Length = 811

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 90  VCHSEED-LVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT 148
           + +SE D L    +L+  LE    S+   L      PG +I   +   +  S+  + +++
Sbjct: 638 ISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLS 697

Query: 149 PGFLQDPWCKYQ 160
           P F+Q+ WC Y+
Sbjct: 698 PNFVQNEWCHYE 709


>gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isoform
           [Homo sapiens]
          Length = 483

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)

Query: 4   STSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSS 63
           S +LP   S+  KP  + +    ++ LK P+  P +P S+S      T   +   P+   
Sbjct: 402 SMALPQEQSQHPKP-SEASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFR 460

Query: 64  VTSPSLPPTHASDSGSSR 81
           +TSP++ P  +SD+ ++R
Sbjct: 461 ITSPTVAPPLSSDTSTNR 478


>gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isoform
           [Homo sapiens]
          Length = 492

 Score = 37.0 bits (84), Expect = 0.015
 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)

Query: 4   STSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSS 63
           S +LP   S+  KP  + +    ++ LK P+  P +P S+S      T   +   P+   
Sbjct: 411 SMALPQEQSQHPKP-SEASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFR 469

Query: 64  VTSPSLPPTHASDSGSSR 81
           +TSP++ P  +SD+ ++R
Sbjct: 470 ITSPTVAPPLSSDTSTNR 487


>gi|16751843 toll-like receptor 5 [Homo sapiens]
          Length = 858

 Score = 36.6 bits (83), Expect = 0.019
 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 8/89 (8%)

Query: 86  YDVCVCHSEEDLVAAQD-LVSYLEGSTASLRCF---LQLRDATPGGAIVSELCQALSSSH 141
           YD  +C S +D    Q+ L+ +L+   +    F    + RD  PG   ++ +  A+ +S 
Sbjct: 693 YDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIWNSR 752

Query: 142 CRVLLITPGFLQDPWCKYQMLQALTEAPG 170
             V L++  FL+D WC    L+A + A G
Sbjct: 753 KIVCLVSRHFLRDGWC----LEAFSYAQG 777


>gi|67906195 ankyrin repeat and sterile alpha motif domain
           containing 6 [Homo sapiens]
          Length = 871

 Score = 36.2 bits (82), Expect = 0.025
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 3   SSTSLPAPGSRPKK----PLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLP 58
           SS   PAPGS P +    P G  A   ++    +  KRP S  ST+S ++ PT   SP P
Sbjct: 687 SSPVGPAPGSSPSELPASPAGGSAPVGKKL---ETSKRPPSGTSTTSKSTSPTLTPSPSP 743

Query: 59  ---PSLSSVTSPSLPPTHASDSGSS 80
               + SSV+S S      S  GSS
Sbjct: 744 KGHTAESSVSSSSSHRQSKSSGGSS 768


>gi|34996489 pleckstrin homology domain interacting protein [Homo
            sapiens]
          Length = 1821

 Score = 35.8 bits (81), Expect = 0.033
 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 24/139 (17%)

Query: 26   RQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTSP--------SLPPTH--AS 75
            R T+ K+ KKR  S   +SS AS P  +   L P L S +S         S+PP H  A 
Sbjct: 1434 RNTITKRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTRSIPPRHNAAQ 1493

Query: 76   DSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDAT--PGGAIVSEL 133
             +G +  S      V  +  + V    +V+    ++++ + F+   +A+  PG  I+   
Sbjct: 1494 INGKTESSS-----VVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKTILEN- 1547

Query: 134  CQALSSSHCRVL--LITPG 150
                S  H + L  L +PG
Sbjct: 1548 ----SVKHSKALNTLSSPG 1562


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
           sapiens]
          Length = 1258

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 9/80 (11%)

Query: 7   LPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTS 66
           LP  G R   P        R     + +K P  P S S+  S PT   SPLP    +  +
Sbjct: 115 LPVEGEREPDPPDD-----RDASDGEDEKPPLPPRSGSTSISAPTGPSSPLP----APET 165

Query: 67  PSLPPTHASDSGSSRWSKDY 86
           P+ P   ++ +G S  S DY
Sbjct: 166 PTAPAAESAPNGLSTVSHDY 185


>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
          Length = 1302

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 11/82 (13%)

Query: 33  PKKRPNSPEST--SSDASQPTSQDSPLPPSLSSVTS--PS---LPPTHASDSGSSRWSKD 85
           P    +SP++   SS   +P+S   PLPP+  S TS  PS   + P+  +  G+S W   
Sbjct: 353 PPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSY 412

Query: 86  YDVCVCHSEEDLVAAQDLVSYL 107
            D    H   +     D+++YL
Sbjct: 413 SD----HFTIETCKETDMLNYL 430


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 8/78 (10%)

Query: 3    SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSS----DASQPTSQDSPLP 58
            ++T+ P P + P  P+         T    P   P+ P +T S      + P    +P P
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502

Query: 59   PSLSSVTSP----SLPPT 72
            P+ + +T P    +LPPT
Sbjct: 1503 PTTTPITPPASTTTLPPT 1520



 Score = 33.1 bits (74), Expect = 0.21
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 11/84 (13%)

Query: 3    SSTSLPAPGSRPKKPLGKMADWFRQTLLK-KPKKRPNSP-------ESTSSDASQPTSQD 54
            ++T+ P P + P  P+         T+    P   P+SP        ST++ +  PT+  
Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMT 1729

Query: 55   SPLP---PSLSSVTSPSLPPTHAS 75
            +P P   PS  + T  +LPPT  S
Sbjct: 1730 TPSPTTTPSPPTTTMTTLPPTTTS 1753



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 6/74 (8%)

Query: 3    SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLS 62
            ++T+ P P + P  P          T    P     SP +T++    PT+  +P PP+ +
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTT 1624

Query: 63   SVTSP----SLPPT 72
             +T P    +LPPT
Sbjct: 1625 PITPPTSTTTLPPT 1638



 Score = 32.0 bits (71), Expect = 0.47
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 3    SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLS 62
            ++T+ P P + P  P          T    P   P SP +T++    PT+  +P PP+ +
Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTP-SPPTTTTTTPPPTT--TPSPPTTT 1545

Query: 63   SVTSP----SLPPT 72
             +T P    +LPPT
Sbjct: 1546 PITPPTSTTTLPPT 1559



 Score = 28.9 bits (63), Expect = 4.0
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 37   PNSPESTSSDASQPTSQDSPLPPS--LSSVTSPSLPPTHASDSG 78
            P +  STSS  ++ T+  S LPP+  ++S   PS P    + SG
Sbjct: 4221 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG 4264


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 11/82 (13%)

Query: 1    MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPE-STSSDASQPTSQD-SPLP 58
            M+ S S  +P   P+ P G           + P   P SP  S +S +  PTS + SP  
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTP--------QSPSYSPTSPSYSPTSPSYSPTSPNYSPTS 1640

Query: 59   PSLSSVTSPSLPPTHASDSGSS 80
            PS S  TSPS  PT  S S +S
Sbjct: 1641 PSYSP-TSPSYSPTSPSYSPTS 1661



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1634 PNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1682



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1641 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1689



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1648 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1696



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1655 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1703



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1662 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1710



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1669 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1717



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1676 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1724



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1683 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1731



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1690 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1738



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  S S +S
Sbjct: 1697 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1745



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 24/50 (48%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S    PTS + SP  PS S  TSPS  PT  S S SS
Sbjct: 1760 PSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP-TSPSYSPTSPSYSPSS 1808



 Score = 28.5 bits (62), Expect = 5.2
 Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS   SP  PS S  TSPS  PT  + S +S
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPNYSPTS 1752



 Score = 27.7 bits (60), Expect = 8.9
 Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS + SP  P+ +  TSPS  PT  S S +S
Sbjct: 1725 PSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTP-TSPSYSPTSPSYSPTS 1773



 Score = 27.7 bits (60), Expect = 8.9
 Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 33   PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
            P   P SP  S +S +  PTS + +P  P+ S  TSPS  PT  S S +S
Sbjct: 1753 PNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSP-TSPSYSPTSPSYSPTS 1801


>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
            [Homo sapiens]
          Length = 1849

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%)

Query: 34   KKRPNSPESTSSDASQPT-SQDSPLPPSLSSVTSPS-LPPTHASDSGSSRWSKDYD 87
            +K+ ++P+S S ++SQPT S DS  P SLS+    S LPP  + D+ +    ++ D
Sbjct: 1440 QKKSDTPQSPSLNSSQPTNSADSKKPASLSNCLPASFLPPPESFDAVADSGIEEVD 1495


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 3    SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLP--PS 60
            S  S P+ G++P  PL   +    Q    +P+ +P  P+        P++  +P+P  P 
Sbjct: 2371 SDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430

Query: 61   LSSVTS--PSLPP 71
              S+TS   SLPP
Sbjct: 2431 QISMTSLQNSLPP 2443



 Score = 27.7 bits (60), Expect = 8.9
 Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 2/41 (4%)

Query: 33   PKKRPNSPESTSSDASQPTSQDSPLPPS--LSSVTSPSLPP 71
            P   P  P S       P S D PL PS  +  V  P+LPP
Sbjct: 2008 PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048


>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
          Length = 541

 Score = 33.1 bits (74), Expect = 0.21
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 2/77 (2%)

Query: 92  HSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITPGF 151
           + EE   A + L   LE       C  + RD  PGGA+V E+   +  S   +++++  +
Sbjct: 389 NGEEHTFAVEILPRVLEKHFGYKLCIFE-RDVVPGGAVVDEIHSLIEKSRRLIIVLSKSY 447

Query: 152 LQDPWCKYQMLQALTEA 168
           + +   +Y++   L EA
Sbjct: 448 MSNE-VRYELESGLHEA 463


>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
           [Homo sapiens]
          Length = 355

 Score = 33.1 bits (74), Expect = 0.21
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 12/78 (15%)

Query: 1   MASSTSLPAPGSRP-------KKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQ 53
           M  S + P P +RP         PL     W+ Q     P  RP  P   ++    P S 
Sbjct: 230 MIQSATPPPPTTRPPPIRPPFSHPLSAHLPWYFQ-----PPPRPLPPRPPAAQPRPPPSP 284

Query: 54  DSPLPPSLSSVTSPSLPP 71
             P PP  S +  P  PP
Sbjct: 285 PPPPPPPPSPLPPPPPPP 302


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score = 33.1 bits (74), Expect = 0.21
 Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 12/78 (15%)

Query: 1   MASSTSLPAPGSRP-------KKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQ 53
           M  S + P P +RP         P+     W+ Q     P  RP  P   ++    P S 
Sbjct: 296 MIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQ-----PPPRPLPPRPPAAQPRPPPSP 350

Query: 54  DSPLPPSLSSVTSPSLPP 71
             P PP  S +  P  PP
Sbjct: 351 PPPPPPPASPLPPPPPPP 368


>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
          Length = 1806

 Score = 32.7 bits (73), Expect = 0.28
 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 35   KRP--NSPESTSSDASQPTSQDSPLPPSL--SSVTSPSLPPTHASDSGSSRWSKD 85
            KRP  +SP  T S A QP S  SP  P +  S V   S+     SD  S +W K+
Sbjct: 1738 KRPEVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKE 1792


>gi|33386674 toll-like receptor adaptor molecule 2 [Homo sapiens]
          Length = 235

 Score = 32.7 bits (73), Expect = 0.28
 Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 90  VCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITP 149
           + H+E+D   A  + + L+     ++  +   +   G   +  L  A++ S   +LL+T 
Sbjct: 83  ILHAEDDTDEALRVQNLLQDDFG-IKPGIIFAEMPCGRQHLQNLDDAVNGSAWTILLLTE 141

Query: 150 GFLQDPWCKYQMLQAL 165
            FL+D WC +Q   +L
Sbjct: 142 NFLRDTWCNFQFYTSL 157


>gi|21735550 mitogen-activated protein kinase kinase kinase 10 [Homo
           sapiens]
          Length = 954

 Score = 32.7 bits (73), Expect = 0.28
 Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 4/63 (6%)

Query: 9   APGSRPKKPLGKMADW----FRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSV 64
           AP  RP     ++  W    F +TL   P  RP++PES    + QPT  D  +       
Sbjct: 884 APRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDS 943

Query: 65  TSP 67
           T P
Sbjct: 944 TVP 946


>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
           [Homo sapiens]
          Length = 639

 Score = 32.3 bits (72), Expect = 0.36
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 4   STSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSS 63
           ST+ P P     +P+ + A     T L+ P   P +PE TS  A  PT+ +    P+ S 
Sbjct: 378 STTEPTPSPTTSEPVPEPAP--NMTTLE-PTPSPTTPEPTSEPAPSPTTPEPTSEPAPSP 434

Query: 64  VTSPSLP-PTHAS 75
            T    P PT A+
Sbjct: 435 TTPEPTPIPTIAT 447


>gi|79749430 FRAS1-related extracellular matrix protein 2 precursor
           [Homo sapiens]
          Length = 3169

 Score = 32.3 bits (72), Expect = 0.36
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 9/114 (7%)

Query: 115 RCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT---PGFLQDPWCKYQMLQA----LTE 167
           R  LQLR   PGGA+V  L   +     ++ ++T   P  +++       L A       
Sbjct: 150 RVRLQLRYDAPGGAVVLPLVLEVEVVFTQLEVVTRNLPLVVEELLGTSNALDARSLEFAF 209

Query: 168 APGAEGCTIPLLSGLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRCKLLQE 221
            P  E C + +LSGL       EL     V G   +GG  +    +M CK  QE
Sbjct: 210 QPETEECRVGILSGLGALPRYGELLHYPQVPGGAREGGAPET--LLMDCKAFQE 261


>gi|169164209 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 179

 Score = 32.0 bits (71), Expect = 0.47
 Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)

Query: 29 LLKKPKKRPNSPESTSSDASQPTSQDSPLP---PSLSSVTSPSLPPTHASDSGSS 80
          +L  P   P +P   +     P S   P P   PS S    P LPP+HAS S  S
Sbjct: 14 ILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRS 68


>gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo
          sapiens]
          Length = 179

 Score = 32.0 bits (71), Expect = 0.47
 Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)

Query: 29 LLKKPKKRPNSPESTSSDASQPTSQDSPLP---PSLSSVTSPSLPPTHASDSGSS 80
          +L  P   P +P   +     P S   P P   PS S    P LPP+HAS S  S
Sbjct: 14 ILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRS 68


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,082,636
Number of Sequences: 37866
Number of extensions: 557018
Number of successful extensions: 4068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 3553
Number of HSP's gapped (non-prelim): 684
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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