Search of human proteins with 22538420

Search of human proteins with 22538420

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22538420 aquaporin 10 [Homo sapiens]
         (301 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22538420 aquaporin 10 [Homo sapiens]                               603   e-173
gi|157266307 aquaporin 9 [Homo sapiens]                               286   1e-77
gi|4826645 aquaporin 3 [Homo sapiens]                                 275   4e-74
gi|4502187 aquaporin 7 [Homo sapiens]                                 234   9e-62
gi|4755125 aquaporin 4 isoform b [Homo sapiens]                        69   5e-12
gi|4502181 aquaporin 4 isoform a [Homo sapiens]                        69   5e-12
gi|37694062 aquaporin 1 [Homo sapiens]                                 65   7e-11
gi|4502183 aquaporin 5 [Homo sapiens]                                  58   9e-09
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]        58   1e-08
gi|4502179 aquaporin 2 [Homo sapiens]                                  57   2e-08
gi|86792455 aquaporin 6 [Homo sapiens]                                 54   2e-07
gi|45446752 aquaporin 8 [Homo sapiens]                                 53   3e-07
gi|27370565 aquaporin 11 [Homo sapiens]                                30   2.0  
gi|21389351 sideroflexin 5 [Homo sapiens]                              30   2.6  
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...    29   4.4  
gi|83281450 galactosylceramidase isoform a precursor [Homo sapiens]    28   7.6  
gi|83281452 galactosylceramidase isoform b precursor [Homo sapiens]    28   7.6  
gi|134304835 killer cell immunoglobulin-like receptor, two domai...    28   9.9  

>gi|22538420 aquaporin 10 [Homo sapiens]
          Length = 301

 Score =  603 bits (1555), Expect = e-173
 Identities = 301/301 (100%), Positives = 301/301 (100%)

Query: 1   MVFTQAPAEIMGHLRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFL 60
           MVFTQAPAEIMGHLRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFL
Sbjct: 1   MVFTQAPAEIMGHLRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFL 60

Query: 61  AGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYV 120
           AGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYV
Sbjct: 61  AGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYV 120

Query: 121 LYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDR 180
           LYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDR
Sbjct: 121 LYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDR 180

Query: 181 RNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNG 240
           RNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNG
Sbjct: 181 RNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNG 240

Query: 241 WWWVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECK 300
           WWWVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECK
Sbjct: 241 WWWVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECK 300

Query: 301 L 301
           L
Sbjct: 301 L 301


>gi|157266307 aquaporin 9 [Homo sapiens]
          Length = 295

 Score =  286 bits (733), Expect = 1e-77
 Identities = 135/257 (52%), Positives = 178/257 (69%)

Query: 14  LRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVG 73
           L ++S LA++ L+EFLG F+L++L  G VAQA+ S    G   T+ +  S+AV +AIYV 
Sbjct: 16  LVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVA 75

Query: 74  GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGN 133
           G VSG H+NPA SLAMC+ GR+ W KLP Y+  Q L AF  +   + +Y+D L ++ GG 
Sbjct: 76  GGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGK 135

Query: 134 LTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVV 193
           L + G   TA IFATYPAPYLSL N F DQV+ T +L++ + AI D RN G P GLEP+ 
Sbjct: 136 LLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIA 195

Query: 194 VGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGA 253
           +G+LI+ +  S+G N G  +NPARDL PRLFT +AGWG EVF AGN +WW+PVV PLVGA
Sbjct: 196 IGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGA 255

Query: 254 TVGTATYQLLVALHHPE 270
            +G   Y L++ +HHPE
Sbjct: 256 VIGGLIYVLVIEIHHPE 272


>gi|4826645 aquaporin 3 [Homo sapiens]
          Length = 292

 Score =  275 bits (703), Expect = 4e-74
 Identities = 138/275 (50%), Positives = 175/275 (63%), Gaps = 4/275 (1%)

Query: 14  LRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVG 73
           L IR  L RQ LAE LG  +L++   G+VAQ V S  T G F T+ LA   AVT+ I + 
Sbjct: 15  LHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIA 74

Query: 74  GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGN 133
           G VSGAHLNPA + AMC + R PW+KLPIY L Q L AF  +G  + LY+DA+ ++    
Sbjct: 75  GQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQ 134

Query: 134 LTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVV 193
           L V+GP  TA IFATYP+ +L + NGF DQ +GT  LIV +LAI+D  N  VP GLE   
Sbjct: 135 LFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFT 194

Query: 194 VGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGA 253
           VG+++L +G SMG N G  +NPARD GPRLFT +AGWG  VF+ G  WWWVP+V+PL+G+
Sbjct: 195 VGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGS 254

Query: 254 TVGTATYQLLVALH----HPEGPEPAQDLVSAQHK 284
             G   YQL++  H     P   E    L   +HK
Sbjct: 255 IAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHK 289


>gi|4502187 aquaporin 7 [Homo sapiens]
          Length = 342

 Score =  234 bits (596), Expect = 9e-62
 Identities = 112/261 (42%), Positives = 169/261 (64%), Gaps = 1/261 (0%)

Query: 20  LARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGA 79
           + R+ LAEF+  +V+M+   G+VA  V + +  G++  + L     VT+ ++V G +SGA
Sbjct: 33  MVREFLAEFMSTYVMMVFGLGSVAHMVLN-KKYGSYLGVNLGFGFGVTMGVHVAGRISGA 91

Query: 80  HLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGP 139
           H+N A + A C +GR+PW K P+Y+L Q L +F A+   Y L++ A+ +++GG L VTGP
Sbjct: 92  HMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGP 151

Query: 140 KETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLIL 199
             TA IFATY   +++L  GFL++   TGML + L AI D+ N     G E +V+G+L++
Sbjct: 152 VATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVV 211

Query: 200 ALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGTAT 259
            +G+S+G N G  +NP+RDL PR+FT++AGWG +VFS G  WWWVPVVAPL+GA +G   
Sbjct: 212 IIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGII 271

Query: 260 YQLLVALHHPEGPEPAQDLVS 280
           Y + +    P  P   +D V+
Sbjct: 272 YLVFIGSTIPREPLKLEDSVA 292


>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
          Length = 301

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 58/244 (23%), Positives = 97/244 (39%), Gaps = 42/244 (17%)

Query: 26  AEFLGVFVLMLLTQGAVAQ-AVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPA 84
           AEFL + + +LL+ G+      T      +   + L   L++   +   G++SG H+NPA
Sbjct: 18  AEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPA 77

Query: 85  FSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETAS 144
            ++AM    ++   K   YI  Q L A   +G  Y+               VT P     
Sbjct: 78  VTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYL---------------VTPPSVVGG 122

Query: 145 IFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLS 204
           +  T     L+  +G L +++ T  L+  + A  D +           V G + LA+G S
Sbjct: 123 LGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD--------VTGSIALAIGFS 174

Query: 205 MGAN-------CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGT 257
           +           G  +NPAR  GP +   +  W            W+  V P++GA +  
Sbjct: 175 VAIGHLFAINYTGASMNPARSFGPAVI--MGNWENH---------WIYWVGPIIGAVLAG 223

Query: 258 ATYQ 261
             Y+
Sbjct: 224 GLYE 227



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 32/129 (24%), Positives = 49/129 (37%), Gaps = 33/129 (25%)

Query: 20  LARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNF-----------------FTMF--- 59
           +A QCL   +G  +L L+T  +V   +      GN                  FT+F   
Sbjct: 97  IAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASC 156

Query: 60  ------LAGSLAVTIAIYV------GGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQ 107
                 + GS+A+ I   V        N +GA +NPA S    ++    W    IY +  
Sbjct: 157 DSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVI-MGNWENHWIYWVGP 215

Query: 108 LLSAFCASG 116
           ++ A  A G
Sbjct: 216 IIGAVLAGG 224


>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
          Length = 323

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 58/244 (23%), Positives = 97/244 (39%), Gaps = 42/244 (17%)

Query: 26  AEFLGVFVLMLLTQGAVAQ-AVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPA 84
           AEFL + + +LL+ G+      T      +   + L   L++   +   G++SG H+NPA
Sbjct: 40  AEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPA 99

Query: 85  FSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETAS 144
            ++AM    ++   K   YI  Q L A   +G  Y+               VT P     
Sbjct: 100 VTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYL---------------VTPPSVVGG 144

Query: 145 IFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLS 204
           +  T     L+  +G L +++ T  L+  + A  D +           V G + LA+G S
Sbjct: 145 LGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD--------VTGSIALAIGFS 196

Query: 205 MGAN-------CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGT 257
           +           G  +NPAR  GP +   +  W            W+  V P++GA +  
Sbjct: 197 VAIGHLFAINYTGASMNPARSFGPAVI--MGNWENH---------WIYWVGPIIGAVLAG 245

Query: 258 ATYQ 261
             Y+
Sbjct: 246 GLYE 249



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 32/129 (24%), Positives = 49/129 (37%), Gaps = 33/129 (25%)

Query: 20  LARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNF-----------------FTMF--- 59
           +A QCL   +G  +L L+T  +V   +      GN                  FT+F   
Sbjct: 119 IAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASC 178

Query: 60  ------LAGSLAVTIAIYV------GGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQ 107
                 + GS+A+ I   V        N +GA +NPA S    ++    W    IY +  
Sbjct: 179 DSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVI-MGNWENHWIYWVGP 237

Query: 108 LLSAFCASG 116
           ++ A  A G
Sbjct: 238 IIGAVLAGG 246


>gi|37694062 aquaporin 1 [Homo sapiens]
          Length = 269

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 67/290 (23%), Positives = 124/290 (42%), Gaps = 35/290 (12%)

Query: 17  RSLLARQCLAEFLGVFVLMLLTQGAVA---QAVTSGETK-GNFFTMFLAGSLAVTIAIYV 72
           + L  R  +AEFL   + + ++ G+       V + +T   +   + LA  L++      
Sbjct: 7   KKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQS 66

Query: 73  GGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGG 132
            G++SGAHLNPA +L + +  ++   +  +YI+ Q + A  A+     +      N  G 
Sbjct: 67  VGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGR 126

Query: 133 NLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPV 192
           N    G               ++   G   +++GT  L++ +LA  DRR + +  G  P+
Sbjct: 127 NDLADG---------------VNSGQGLGIEIIGTLQLVLCVLATTDRRRRDL-GGSAPL 170

Query: 193 VVGMLILALGLSMGAN-CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGW-WWVPVVAPL 250
            +G L +ALG  +  +  G  +NPAR  G  + T+         +  N W +W   V P 
Sbjct: 171 AIG-LSVALGHLLAIDYTGCGINPARSFGSAVITH---------NFSNHWIFW---VGPF 217

Query: 251 VGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECK 300
           +G  +    Y  ++A    +  +  +   S Q +  +L+       +E K
Sbjct: 218 IGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMK 267


>gi|4502183 aquaporin 5 [Homo sapiens]
          Length = 265

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 62/240 (25%), Positives = 100/240 (41%), Gaps = 31/240 (12%)

Query: 26  AEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPAF 85
           AEFL   + +    G+  +  ++  T      + LA  LA+       G VSG H+NPA 
Sbjct: 16  AEFLATLIFVFFGLGSALKWPSALPT---ILQIALAFGLAIGTLAQALGPVSGGHINPAI 72

Query: 86  SLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETASI 145
           +LA+ +  ++  ++   Y+  QL+ A   +G   +LY  A  N   GNL V         
Sbjct: 73  TLALLVGNQISLLRAFFYVAAQLVGAIAGAG---ILYGVAPLN-ARGNLAVNALNNNT-- 126

Query: 146 FATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLSM 205
                    +     + +++ T  L + + A  D R    P G   + +G L + LG  +
Sbjct: 127 ---------TQGQAMVVELILTFQLALCIFASTDSRRTS-PVGSPALSIG-LSVTLGHLV 175

Query: 206 GAN-CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGTATYQLLV 264
           G    G  +NPAR  GP +          V +  +   WV  V P+VGA +    Y  L+
Sbjct: 176 GIYFTGCSMNPARSFGPAV----------VMNRFSPAHWVFWVGPIVGAVLAAILYFYLL 225


>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
          Length = 263

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 53/207 (25%), Positives = 85/207 (41%), Gaps = 31/207 (14%)

Query: 60  LAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATY 119
           +A  LA+   +   G++SGAH+NPA + A  +  ++  ++   Y+  QLL A   +   Y
Sbjct: 46  MAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLY 105

Query: 120 VLYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILD 179
                          +VT P    ++      P +S+      ++  T   ++ + A  D
Sbjct: 106 ---------------SVTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYD 150

Query: 180 RRNKGVPAGLEPVVVGMLILALGLSMGA-NCGIPLNPARDLGPRLFTYVAGWGPEVFSAG 238
            R  G   G   + VG   LALG   G    G  +NPAR   P + T            G
Sbjct: 151 ERRNG-QLGSVALAVG-FSLALGHLFGMYYTGAGMNPARSFAPAILT------------G 196

Query: 239 NGW-WWVPVVAPLVGATVGTATYQLLV 264
           N    WV  V P++G  +G+  Y  L+
Sbjct: 197 NFTNHWVYWVGPIIGGGLGSLLYDFLL 223


>gi|4502179 aquaporin 2 [Homo sapiens]
          Length = 271

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 35/252 (13%)

Query: 16  IRSL-LARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGG 74
           +RS+  +R   AEFL   + +    G+   A+   +   +   + +A  L +   +   G
Sbjct: 4   LRSIAFSRAVFAEFLATLLFVFFGLGS---ALNWPQALPSVLQIAMAFGLGIGTLVQALG 60

Query: 75  NVSGAHLNPAFSLAMCIVG-RLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGN 133
           ++SGAH+NPA ++A C+VG  +  ++   Y+  QLL A   +     L H+       G+
Sbjct: 61  HISGAHINPAVTVA-CLVGCHVSVLRAAFYVAAQLLGAVAGA----ALLHEITPADIRGD 115

Query: 134 LTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVV 193
           L V     +            +       ++  T  L++ + A  D R +G   G   + 
Sbjct: 116 LAVNALSNST-----------TAGQAVTVELFLTLQLVLCIFASTDER-RGENPGTPALS 163

Query: 194 VGMLILALGLSMGAN-CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVG 252
           +G  + ALG  +G +  G  +NPAR L P + T                 WV  + PLVG
Sbjct: 164 IGFSV-ALGHLLGIHYTGCSMNPARSLAPAVVT-----------GKFDDHWVFWIGPLVG 211

Query: 253 ATVGTATYQLLV 264
           A +G+  Y  ++
Sbjct: 212 AILGSLLYNYVL 223



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 23/86 (26%), Positives = 38/86 (44%)

Query: 7   PAEIMGHLRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAV 66
           PA+I G L + +L       + + V + + L       A T      N  T  L+   +V
Sbjct: 109 PADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSV 168

Query: 67  TIAIYVGGNVSGAHLNPAFSLAMCIV 92
            +   +G + +G  +NPA SLA  +V
Sbjct: 169 ALGHLLGIHYTGCSMNPARSLAPAVV 194


>gi|86792455 aquaporin 6 [Homo sapiens]
          Length = 282

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 60/256 (23%), Positives = 105/256 (41%), Gaps = 44/256 (17%)

Query: 15  RIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGG 74
           R+   ++R   AEFL   + +    G+V +  T+     +   + +  +L   +A+ V  
Sbjct: 18  RLWKAISRALFAEFLATGLYVFFGVGSVMRWPTA---LPSVLQIAITFNLVTAMAVQVTW 74

Query: 75  NVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNL 134
             SGAH NPA +LA  +   +   +   Y+  QL+ A   +   Y +    ++   G N+
Sbjct: 75  KASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINV 134

Query: 135 TVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILD-RRNKGVPAGLEPVV 193
                              +S       ++L T  L++ + A  D R+  G PA     +
Sbjct: 135 VRNS---------------VSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPA----TM 175

Query: 194 VGMLILALGLSMGAN-CGIPLNPARDLGPRL----FTYVAGWGPEVFSAGNGWWWVPVVA 248
           +G+ + ALG  +G +  G  +NPAR  GP +    FT                 WV  V 
Sbjct: 176 IGISV-ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTV---------------HWVFWVG 219

Query: 249 PLVGATVGTATYQLLV 264
           PL+GA + +  Y  ++
Sbjct: 220 PLMGALLASLIYNFVL 235


>gi|45446752 aquaporin 8 [Homo sapiens]
          Length = 261

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 22/200 (11%)

Query: 24  CLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNP 83
           CL E LG  + + +       +V    T        LA  LA+ + I   GN+SG H NP
Sbjct: 38  CLVELLGSALFIFIG----CLSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNP 93

Query: 84  AFSLAMCIVGRLPWVKLPIYILVQLLSAFC-ASGATYVLYHDALQNYTGGN-LTVTGPKE 141
           A SLA  ++G L  V L  Y + QLL     A+ A  V   +   N +G   +TV    +
Sbjct: 94  AVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQ 153

Query: 142 TASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILAL 201
            A                  + +L T + +   +  ++ + KG    L P  +G  +   
Sbjct: 154 VAGALVA-------------EIILTTLLALAVCMGAINEKTKG---PLAPFSIGFAVTVD 197

Query: 202 GLSMGANCGIPLNPARDLGP 221
            L+ G   G  +NPAR  GP
Sbjct: 198 ILAGGPVSGGCMNPARAFGP 217



 Score = 31.6 bits (70), Expect = 0.90
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 23  QCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLN 82
           Q     +   +L  L   AV     + +TKG      +    AVT+ I  GG VSG  +N
Sbjct: 153 QVAGALVAEIILTTLLALAVCMGAINEKTKGPLAPFSIG--FAVTVDILAGGPVSGGCMN 210

Query: 83  PAFSLAMCIVGRLPWVKLPIYILVQLLS 110
           PA +    +V    W    IY L  LL+
Sbjct: 211 PARAFGPAVVAN-HWNFHWIYWLGPLLA 237


>gi|27370565 aquaporin 11 [Homo sapiens]
          Length = 271

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 66  VTIAIYVGGNVSGAHLNPAFSLA---MCIVGRLP------WVKLPIYILVQLL 109
           +T  +Y GG+++GA  NPA +L+   MC     P      W+   + IL+ +L
Sbjct: 200 ITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMIL 252


>gi|21389351 sideroflexin 5 [Homo sapiens]
          Length = 340

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 13/65 (20%)

Query: 123 HDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRN 182
           H+A  NY   N             AT P+P      G+L  V+    + VGL  ++ + N
Sbjct: 143 HNACVNYANRN-------------ATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKAN 189

Query: 183 KGVPA 187
           K  PA
Sbjct: 190 KFTPA 194


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 22/49 (44%), Positives = 26/49 (53%), Gaps = 10/49 (20%)

Query: 60  LAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
           LAGS A T     G +VS   LN  FS+ M     L W+ LPIYI  Q+
Sbjct: 87  LAGSGAAT-----GISVSAYELNGLFSVLM-----LAWIFLPIYIAGQV 125


>gi|83281450 galactosylceramidase isoform a precursor [Homo sapiens]
          Length = 685

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 1/49 (2%)

Query: 108 LLSAFCASGATYVLYH-DALQNYTGGNLTVTGPKETASIFATYPAPYLS 155
           LL A  A G  YVL   D L     G   V+G   T+ +   YP PY S
Sbjct: 32  LLCALLAPGGAYVLDDSDGLGREFDGIGAVSGGGATSRLLVNYPEPYRS 80


>gi|83281452 galactosylceramidase isoform b precursor [Homo sapiens]
          Length = 407

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 1/49 (2%)

Query: 108 LLSAFCASGATYVLYH-DALQNYTGGNLTVTGPKETASIFATYPAPYLS 155
           LL A  A G  YVL   D L     G   V+G   T+ +   YP PY S
Sbjct: 32  LLCALLAPGGAYVLDDSDGLGREFDGIGAVSGGGATSRLLVNYPEPYRS 80


>gi|134304835 killer cell immunoglobulin-like receptor, two domains,
           short cytoplasmic tail, 5 [Homo sapiens]
          Length = 304

 Score = 28.1 bits (61), Expect = 9.9
 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 6/108 (5%)

Query: 49  GETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLN-PAFSLAMCIVGRLPWVKL-----PI 102
           G +KGNF    +   LA T   Y     S   L+ P+  L + I G      L     P 
Sbjct: 79  GVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 138

Query: 103 YILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETASIFATYP 150
            +  + ++  C+S ++Y +YH + +          GPK   +  A +P
Sbjct: 139 VLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFP 186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,220,177
Number of Sequences: 37866
Number of extensions: 505161
Number of successful extensions: 1068
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1028
Number of HSP's gapped (non-prelim): 26
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.