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Search of human proteins with 224831251
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
(997 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 1988 0.0
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 1977 0.0
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 1910 0.0
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 1903 0.0
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 1899 0.0
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 1888 0.0
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 1821 0.0
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 1814 0.0
gi|56549125 dynamin 2 isoform 4 [Homo sapiens] 114 5e-25
gi|56549123 dynamin 2 isoform 2 [Homo sapiens] 114 5e-25
gi|56549121 dynamin 2 isoform 1 [Homo sapiens] 114 5e-25
gi|56549119 dynamin 2 isoform 3 [Homo sapiens] 114 5e-25
gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 107 6e-23
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 107 6e-23
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] 104 4e-22
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] 104 4e-22
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] 104 4e-22
gi|42544243 dynamin 3 isoform a [Homo sapiens] 103 8e-22
gi|209915561 dynamin 3 isoform b [Homo sapiens] 103 8e-22
gi|222136619 myxovirus resistance protein 1 [Homo sapiens] 102 2e-21
gi|222136617 myxovirus resistance protein 1 [Homo sapiens] 102 2e-21
gi|11342664 myxovirus resistance protein 2 [Homo sapiens] 99 3e-20
gi|116235456 ring finger protein 214 [Homo sapiens] 43 0.002
gi|116235451 ring finger protein 214 [Homo sapiens] 43 0.002
gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 42 0.002
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 42 0.003
gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 42 0.003
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 41 0.006
gi|224593756 hypothetical protein LOC164127 [Homo sapiens] 40 0.011
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 39 0.024
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 1988 bits (5150), Expect = 0.0
Identities = 997/997 (100%), Positives = 997/997 (100%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 181 DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 240
DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA
Sbjct: 181 DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 240
Query: 241 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 300
QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS
Sbjct: 241 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 300
Query: 301 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 360
LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT
Sbjct: 301 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 360
Query: 361 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 420
RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS
Sbjct: 361 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 420
Query: 421 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 480
LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA
Sbjct: 421 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 480
Query: 481 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 540
ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT
Sbjct: 481 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 540
Query: 541 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 600
GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ
Sbjct: 541 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 600
Query: 601 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 660
ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS
Sbjct: 601 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 660
Query: 661 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 720
LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR
Sbjct: 661 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 720
Query: 721 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 780
FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA
Sbjct: 721 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 780
Query: 781 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 840
AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE
Sbjct: 781 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 840
Query: 841 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 900
EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY
Sbjct: 841 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 900
Query: 901 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 960
QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK
Sbjct: 901 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 960
Query: 961 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 961 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 1977 bits (5121), Expect = 0.0
Identities = 997/1015 (98%), Positives = 997/1015 (98%), Gaps = 18/1015 (1%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 181 DFFTSG------------------SPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 222
DFFTSG SPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ
Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 240
Query: 223 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 282
EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK
Sbjct: 241 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 300
Query: 283 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 342
LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL
Sbjct: 301 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 360
Query: 343 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 402
EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL
Sbjct: 361 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 420
Query: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462
RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY
Sbjct: 421 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 480
Query: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522
MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI
Sbjct: 481 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 540
Query: 523 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 582
IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS
Sbjct: 541 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 600
Query: 583 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 642
LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV
Sbjct: 601 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 660
Query: 643 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 702
ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL
Sbjct: 661 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 720
Query: 703 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 762
PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI
Sbjct: 721 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 780
Query: 763 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 822
QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ
Sbjct: 781 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 840
Query: 823 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 882
CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF
Sbjct: 841 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 900
Query: 883 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 942
LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR
Sbjct: 901 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 960
Query: 943 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 961 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 1015
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 1910 bits (4948), Expect = 0.0
Identities = 965/998 (96%), Positives = 969/998 (97%), Gaps = 20/998 (2%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF-EKIRKALPSSEDLVKLAPDFDKIVESLSLL 179
QWKDMIPDLSEYKWIVPDIVWEIDEYIDF K+ + + DL+ L
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLL------------- 167
Query: 180 KDFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY 239
GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY
Sbjct: 168 ------GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY 221
Query: 240 AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 299
AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK
Sbjct: 222 AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 281
Query: 300 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 359
SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM
Sbjct: 282 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 341
Query: 360 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 419
TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI
Sbjct: 342 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 401
Query: 420 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 479
SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD
Sbjct: 402 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 461
Query: 480 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 539
AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV
Sbjct: 462 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 521
Query: 540 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 599
TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ
Sbjct: 522 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 581
Query: 600 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 659
QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ
Sbjct: 582 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 641
Query: 660 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 719
SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS
Sbjct: 642 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 701
Query: 720 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 779
RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD
Sbjct: 702 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 761
Query: 780 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 839
AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN
Sbjct: 762 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 821
Query: 840 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 899
EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY
Sbjct: 822 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 881
Query: 900 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 959
YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE
Sbjct: 882 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 941
Query: 960 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 942 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 979
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 1903 bits (4929), Expect = 0.0
Identities = 961/997 (96%), Positives = 961/997 (96%), Gaps = 36/997 (3%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDF
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149
Query: 181 DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 240
GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA
Sbjct: 150 -----GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 204
Query: 241 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 300
QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS
Sbjct: 205 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 264
Query: 301 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 360
LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT
Sbjct: 265 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 324
Query: 361 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 420
RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS
Sbjct: 325 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 384
Query: 421 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 480
LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA
Sbjct: 385 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 444
Query: 481 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 540
ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT
Sbjct: 445 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 504
Query: 541 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 600
GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ
Sbjct: 505 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 564
Query: 601 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 660
ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS
Sbjct: 565 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 624
Query: 661 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 720
LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR
Sbjct: 625 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 684
Query: 721 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 780
FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA
Sbjct: 685 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 744
Query: 781 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 840
AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE
Sbjct: 745 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 804
Query: 841 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 900
EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY
Sbjct: 805 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 864
Query: 901 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 960
QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK
Sbjct: 865 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 924
Query: 961 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 925 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 961
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 1899 bits (4920), Expect = 0.0
Identities = 960/997 (96%), Positives = 960/997 (96%), Gaps = 37/997 (3%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 181 DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 240
DFFTSGSPEETAFRATDRGSESDKHF
Sbjct: 181 DFFTSGSPEETAFRATDRGSESDKHF---------------------------------- 206
Query: 241 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 300
RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS
Sbjct: 207 ---RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 263
Query: 301 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 360
LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT
Sbjct: 264 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 323
Query: 361 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 420
RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS
Sbjct: 324 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 383
Query: 421 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 480
LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA
Sbjct: 384 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 443
Query: 481 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 540
ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT
Sbjct: 444 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 503
Query: 541 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 600
GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ
Sbjct: 504 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 563
Query: 601 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 660
ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS
Sbjct: 564 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 623
Query: 661 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 720
LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR
Sbjct: 624 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 683
Query: 721 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 780
FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA
Sbjct: 684 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 743
Query: 781 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 840
AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE
Sbjct: 744 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 803
Query: 841 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 900
EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY
Sbjct: 804 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 863
Query: 901 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 960
QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK
Sbjct: 864 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 923
Query: 961 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 924 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 960
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 1888 bits (4891), Expect = 0.0
Identities = 960/1015 (94%), Positives = 960/1015 (94%), Gaps = 55/1015 (5%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 181 DFFTSG------------------SPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 222
DFFTSG SPEETAFRATDRGSESDKHFR
Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFR--------------- 225
Query: 223 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 282
KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK
Sbjct: 226 ----------------------KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263
Query: 283 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 342
LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL
Sbjct: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323
Query: 343 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 402
EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL
Sbjct: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383
Query: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462
RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY
Sbjct: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443
Query: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522
MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI
Sbjct: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503
Query: 523 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 582
IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS
Sbjct: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563
Query: 583 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 642
LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV
Sbjct: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623
Query: 643 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 702
ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL
Sbjct: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683
Query: 703 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 762
PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI
Sbjct: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743
Query: 763 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 822
QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ
Sbjct: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803
Query: 823 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 882
CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF
Sbjct: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863
Query: 883 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 942
LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR
Sbjct: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923
Query: 943 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 1821 bits (4718), Expect = 0.0
Identities = 928/998 (92%), Positives = 932/998 (93%), Gaps = 57/998 (5%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF-EKIRKALPSSEDLVKLAPDFDKIVESLSLL 179
QWKDMIPDLSEYKWIVPDIVWEIDEYIDF K+ + + DL+ L
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLL------------- 167
Query: 180 KDFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY 239
GSPEETAFRATDRGSESDKHF
Sbjct: 168 ------GSPEETAFRATDRGSESDKHF--------------------------------- 188
Query: 240 AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 299
RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK
Sbjct: 189 ----RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 244
Query: 300 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 359
SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM
Sbjct: 245 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 304
Query: 360 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 419
TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI
Sbjct: 305 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 364
Query: 420 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 479
SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD
Sbjct: 365 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 424
Query: 480 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 539
AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV
Sbjct: 425 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 484
Query: 540 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 599
TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ
Sbjct: 485 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 544
Query: 600 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 659
QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ
Sbjct: 545 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 604
Query: 660 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 719
SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS
Sbjct: 605 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 664
Query: 720 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 779
RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD
Sbjct: 665 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 724
Query: 780 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 839
AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN
Sbjct: 725 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 784
Query: 840 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 899
EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY
Sbjct: 785 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 844
Query: 900 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 959
YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE
Sbjct: 845 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 904
Query: 960 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 905 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 942
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 1814 bits (4699), Expect = 0.0
Identities = 924/997 (92%), Positives = 924/997 (92%), Gaps = 73/997 (7%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDF
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149
Query: 181 DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 240
GSPEETAFRATDRGSESDKHFR
Sbjct: 150 -----GSPEETAFRATDRGSESDKHFR--------------------------------- 171
Query: 241 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 300
KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS
Sbjct: 172 ----KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 227
Query: 301 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 360
LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT
Sbjct: 228 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 287
Query: 361 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 420
RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS
Sbjct: 288 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 347
Query: 421 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 480
LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA
Sbjct: 348 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 407
Query: 481 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 540
ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT
Sbjct: 408 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 467
Query: 541 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 600
GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ
Sbjct: 468 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 527
Query: 601 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 660
ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS
Sbjct: 528 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 587
Query: 661 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 720
LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR
Sbjct: 588 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 647
Query: 721 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 780
FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA
Sbjct: 648 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 707
Query: 781 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 840
AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE
Sbjct: 708 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 767
Query: 841 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 900
EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY
Sbjct: 768 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 827
Query: 901 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 960
QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK
Sbjct: 828 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 887
Query: 961 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 888 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 924
>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
Length = 866
Score = 114 bits (285), Expect = 5e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 539 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 596 SVEQQADSFKATRFNLE---TEWKNNYP 620
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
Length = 870
Score = 114 bits (285), Expect = 5e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 539 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 596 SVEQQADSFKATRFNLE---TEWKNNYP 620
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
Length = 870
Score = 114 bits (285), Expect = 5e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 539 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 596 SVEQQADSFKATRFNLE---TEWKNNYP 620
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
Length = 866
Score = 114 bits (285), Expect = 5e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 539 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 596 SVEQQADSFKATRFNLE---TEWKNNYP 620
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
Length = 851
Score = 107 bits (267), Expect = 6e-23
Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + + + D S N LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
+TR P+ + L A F + K D +R EIE + +SP
Sbjct: 64 VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + LVDLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S + ++DP G+RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 539 VTGKG---NSSESIEAIREYEEEFF 560
V + + I A E +FF
Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 107 bits (267), Expect = 6e-23
Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + + + D S N LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
+TR P+ + L A F + K D +R EIE + +SP
Sbjct: 64 VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + LVDLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S + ++DP G+RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 539 VTGKG---NSSESIEAIREYEEEFF 560
V + + I A E +FF
Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259
>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
Length = 736
Score = 104 bits (260), Expect = 4e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
Query: 359 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 402
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
Query: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
Query: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
Query: 523 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 561
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
Length = 699
Score = 104 bits (260), Expect = 4e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
Query: 359 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 402
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
Query: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
Query: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
Query: 523 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 561
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
Length = 710
Score = 104 bits (260), Expect = 4e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
Query: 359 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 402
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
Query: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
Query: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
Query: 523 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 561
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
>gi|42544243 dynamin 3 isoform a [Homo sapiens]
Length = 863
Score = 103 bits (257), Expect = 8e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
Query: 539 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
Query: 596 SVEQQADSFKATRFNLETE---WKNNYP 620
++ + + ++E E +KN P
Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
>gi|209915561 dynamin 3 isoform b [Homo sapiens]
Length = 859
Score = 103 bits (257), Expect = 8e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
Query: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
Query: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
Query: 539 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
Query: 596 SVEQQADSFKATRFNLETE---WKNNYP 620
++ + + ++E E +KN P
Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 102 bits (253), Expect = 2e-21
Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%)
Query: 284 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 342
V QK+ + L + +D++ A QD LP + V+GDQS+GK+SVL
Sbjct: 28 VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87
Query: 343 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 401
E ++ + PRGSG ++TR P+ + L + + K S +++++ + D + + EI
Sbjct: 88 EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144
Query: 402 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 461
EG +S E I+L + + + L+DLPG+ D I ++ K
Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204
Query: 462 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 521
Y+Q I L + +VD + + ++DP G RTI +LTK DL +K + ++
Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262
Query: 522 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 577
++ +F +K GY +V +G S+ + E+ FF+N + +L+ + T
Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319
Query: 578 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 633
L+ ++ + +S+ + K T + E + + E D NE L +K
Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378
Query: 634 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 689
N ++ +L Q EE ++ R H +IEN + + + +
Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432
Query: 690 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 747
+ Q+ ++LP +ET+ ++ + + EP + D ++ A + SIK
Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490
>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 102 bits (253), Expect = 2e-21
Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%)
Query: 284 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 342
V QK+ + L + +D++ A QD LP + V+GDQS+GK+SVL
Sbjct: 28 VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87
Query: 343 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 401
E ++ + PRGSG ++TR P+ + L + + K S +++++ + D + + EI
Sbjct: 88 EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144
Query: 402 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 461
EG +S E I+L + + + L+DLPG+ D I ++ K
Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204
Query: 462 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 521
Y+Q I L + +VD + + ++DP G RTI +LTK DL +K + ++
Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262
Query: 522 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 577
++ +F +K GY +V +G S+ + E+ FF+N + +L+ + T
Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319
Query: 578 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 633
L+ ++ + +S+ + K T + E + + E D NE L +K
Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378
Query: 634 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 689
N ++ +L Q EE ++ R H +IEN + + + +
Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432
Query: 690 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 747
+ Q+ ++LP +ET+ ++ + + EP + D ++ A + SIK
Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490
>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
Length = 715
Score = 98.6 bits (244), Expect = 3e-20
Identities = 65/214 (30%), Positives = 107/214 (50%), Gaps = 6/214 (2%)
Query: 325 LPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSRE 384
LP + V+GDQS+GK+SVLE ++ + PRGSG ++TR P+ + L + P + S R
Sbjct: 118 LPAIAVIGDQSSGKSSVLEALSGVAL-PRGSG-IVTRCPLVLKLKKQPCEAWAGRISYRN 175
Query: 385 FDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVT 444
+L + +D + EI G +S E ISL + P + + ++DLPG+
Sbjct: 176 TEL-ELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAV 234
Query: 445 SGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLT 504
D I ++ K Y+Q I L + +VD + + ++DP G RTI +LT
Sbjct: 235 DNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILT 294
Query: 505 KVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
K DL ++ + + ++ +P+K GY V
Sbjct: 295 KPDLMDR--GTEKSVMNVVRNLTYPLKK-GYMIV 325
>gi|116235456 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 42.7 bits (99), Expect = 0.002
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 18/205 (8%)
Query: 144 DEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESD 203
D +DF + E V++ D D+ SL L ++ +T F+ D +D
Sbjct: 166 DTSLDFRPVVSPANGVEG-VRVDQDDDQDSSSLKLSQNIAV-----QTDFKTADSEVNTD 219
Query: 204 KHFRKGL---LGELILLQQQIQEHEEEARRAAGQYSTSYAQ-QKRKVSDKEKIDQLQEEL 259
+ K L + E LL+++ QE ++ R+ Q Q Q+R+ + + ++ + +
Sbjct: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Query: 260 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 319
+K + +++EKE KE L ++D K + +K +++ LD L + D
Sbjct: 280 QDVTIKREETKKKIEKEKKEF--LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEI 337
Query: 320 NTQDHLPRVVVVGDQSAGKTSVLEM 344
N R ++ + A K +L +
Sbjct: 338 N------RNIMEETERAWKAEILSL 356
>gi|116235451 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 42.7 bits (99), Expect = 0.002
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 18/205 (8%)
Query: 144 DEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESD 203
D +DF + E V++ D D+ SL L ++ +T F+ D +D
Sbjct: 166 DTSLDFRPVVSPANGVEG-VRVDQDDDQDSSSLKLSQNIAV-----QTDFKTADSEVNTD 219
Query: 204 KHFRKGL---LGELILLQQQIQEHEEEARRAAGQYSTSYAQ-QKRKVSDKEKIDQLQEEL 259
+ K L + E LL+++ QE ++ R+ Q Q Q+R+ + + ++ + +
Sbjct: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Query: 260 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 319
+K + +++EKE KE L ++D K + +K +++ LD L + D
Sbjct: 280 QDVTIKREETKKKIEKEKKEF--LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEI 337
Query: 320 NTQDHLPRVVVVGDQSAGKTSVLEM 344
N R ++ + A K +L +
Sbjct: 338 N------RNIMEETERAWKAEILSL 356
>gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform a [Homo sapiens]
Length = 445
Score = 42.4 bits (98), Expect = 0.002
Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 27/199 (13%)
Query: 116 KKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKI---RKALPSSEDLVKLAPDFDKI 172
K F ++D I D E KW W+ DE + E I +K + + ++ + KI
Sbjct: 218 KNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKI 277
Query: 173 VESLSLLKDFFTSGSPEETAFRATD---------------RGSESDKHFRKGLLGELILL 217
ES S + + F E +D R + ++H+ +L +L+L+
Sbjct: 278 NESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVPWRRDQINRHWHD-VLQQLLLM 336
Query: 218 QQQIQEHEEEA----RRAAGQYSTSYAQQKRK--VSDKEKIDQLQEELLHTQLKYQRILE 271
Q +E +A Y T QK K V + EK+ LQ + T+ KY+ ++
Sbjct: 337 QVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKM--LQTKFAETEEKYKHTIQ 394
Query: 272 RLEKENKELRKLVLQKDDK 290
L +EN L++ ++ K+++
Sbjct: 395 ILTEENIHLKQKIISKNEE 413
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 42.0 bits (97), Expect = 0.003
Identities = 33/179 (18%), Positives = 86/179 (48%), Gaps = 11/179 (6%)
Query: 144 DEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESD 203
D + K+ K ++E+ VK + E ++ L++ + + E+ + + + + D
Sbjct: 960 DLELTLTKVEKEKHATENKVK------NLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013
Query: 204 KHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA---QQKRKVSDKEKIDQLQEELL 260
+ + LI + ++++ ++ + Q A + KRK+ K+ Q E ++
Sbjct: 1014 LQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQ--ESIM 1071
Query: 261 HTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 319
+ Q+I E+L+K+ EL +L + DD+ +H + +K + ++ + + ++ + +A +
Sbjct: 1072 DLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEH 1130
>gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform b [Homo sapiens]
Length = 422
Score = 42.0 bits (97), Expect = 0.003
Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 12/180 (6%)
Query: 116 KKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKI---RKALPSSEDLVKLAPDFDKI 172
K F ++D I D E KW W+ DE + E I +K + + ++ + KI
Sbjct: 218 KNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKI 277
Query: 173 VESLSLLKDFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAA 232
ES S + + F E +D + K ++ E + Q I E
Sbjct: 278 NESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLN-----T 332
Query: 233 GQYSTSYAQQKRK--VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDK 290
Y T QK K V + EK+ LQ + T+ KY+ ++ L +EN L++ ++ K+++
Sbjct: 333 NLYYTQLELQKEKAIVGNLEKM--LQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEE 390
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 40.8 bits (94), Expect = 0.006
Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 7/92 (7%)
Query: 215 ILLQQQIQEHEEEARRAAGQYSTSYAQQKRK-------VSDKEKIDQLQEELLHTQLKYQ 267
+L + Q QE A+ A Q + A++KRK + +EKI ++Q+ + +L+ Q
Sbjct: 903 LLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQ 962
Query: 268 RILERLEKENKELRKLVLQKDDKGIHHRKLKK 299
+ILE +K+ +E L + +K I +++++
Sbjct: 963 QILEAKKKKKEEAANAKLLEAEKRIKEKEMRR 994
>gi|224593756 hypothetical protein LOC164127 [Homo sapiens]
Length = 623
Score = 40.0 bits (92), Expect = 0.011
Identities = 36/158 (22%), Positives = 75/158 (47%), Gaps = 6/158 (3%)
Query: 198 RGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSD--KEKIDQL 255
R E + RK EL Q+ +E ++AR AG+ +KR + + EKI Q
Sbjct: 458 RSQEIHQGLRKERQRELREKAQKEEEQLQQARWRAGESEEQRKMRKRILVELADEKIRQA 517
Query: 256 QEELLHT---QLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVL 312
+ + T ++++ R L L ++N + KL +K++K H +K+++ V +
Sbjct: 518 RSHVHKTTRDKVQHLRELNHLREKNHHILKLKAEKEEK-CHIEGIKEAIKKKEQRVQHIS 576
Query: 313 SDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARI 350
D ++ LP+ +++ +S+ +M+ +A++
Sbjct: 577 QGKDPNFQEFQKLPQASRREERAPPNSSLDQMVLEAQL 614
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 38.9 bits (89), Expect = 0.024
Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%)
Query: 549 IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 608
+ + + F+ K LK +++ LS + E + QQ + ++A
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209
Query: 609 FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 668
NLE + + +E DR +L +K E DE I + K E++++ L E+V
Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267
Query: 669 VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 717
+ PA + + + +++ K +K + +E + EE
Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327
Query: 718 ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 770
F+ +T K ++ + D+ DKLK ++++ + +ED R+++ +
Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387
Query: 771 SIS 773
+S
Sbjct: 1388 EVS 1390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,706,212
Number of Sequences: 37866
Number of extensions: 1590192
Number of successful extensions: 8687
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 7627
Number of HSP's gapped (non-prelim): 1383
length of query: 997
length of database: 18,247,518
effective HSP length: 112
effective length of query: 885
effective length of database: 14,006,526
effective search space: 12395775510
effective search space used: 12395775510
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.