Guide to the Human Genome
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Search of human proteins with 115511057

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
         (682 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115511057 hypothetical protein LOC256643 [Homo sapiens]           1422   0.0  
gi|167234419 thyroid hormone receptor associated protein 3 [Homo...   105   2e-22
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H...   104   2e-22
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom...   104   2e-22
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H...   103   4e-22
gi|239756568 PREDICTED: similar to BCL2-associated transcription...   101   3e-21
gi|169218320 PREDICTED: similar to BCL2-associated transcription...   101   3e-21
gi|87299628 biorientation of chromosomes in cell division 1-like...    61   4e-09
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  50   9e-06
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        48   3e-05
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    44   5e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    44   5e-04
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]             44   6e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     43   8e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom...    42   0.002
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    41   0.004
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]              40   0.007
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]             40   0.007
gi|60097902 filaggrin [Homo sapiens]                                   39   0.016
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    39   0.016
gi|34098946 nuclease sensitive element binding protein 1 [Homo s...    38   0.027
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    38   0.035
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        38   0.035
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       37   0.060
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    37   0.079
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    37   0.079
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            37   0.079
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     36   0.10 
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap...    36   0.10 
gi|52426743 cisplatin resistance-associated overexpressed protei...    36   0.10 

>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
          Length = 682

 Score = 1422 bits (3680), Expect = 0.0
 Identities = 682/682 (100%), Positives = 682/682 (100%)

Query: 1   MARSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSK 60
           MARSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSK
Sbjct: 1   MARSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSK 60

Query: 61  PRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGI 120
           PRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGI
Sbjct: 61  PRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGI 120

Query: 121 PYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQ 180
           PYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQ
Sbjct: 121 PYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQ 180

Query: 181 EEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKP 240
           EEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKP
Sbjct: 181 EEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKP 240

Query: 241 EHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRT 300
           EHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRT
Sbjct: 241 EHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRT 300

Query: 301 QKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDV 360
           QKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDV
Sbjct: 301 QKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDV 360

Query: 361 DLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKT 420
           DLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKT
Sbjct: 361 DLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKT 420

Query: 421 VDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIH 480
           VDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIH
Sbjct: 421 VDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIH 480

Query: 481 QVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYE 540
           QVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYE
Sbjct: 481 QVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYE 540

Query: 541 SEQTLIKIIDPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKNYTTQRKDI 600
           SEQTLIKIIDPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKNYTTQRKDI
Sbjct: 541 SEQTLIKIIDPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKNYTTQRKDI 600

Query: 601 ITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPNYKSGLVQKSLYIQAKYQRLRFTGPRGFI 660
           ITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPNYKSGLVQKSLYIQAKYQRLRFTGPRGFI
Sbjct: 601 ITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPNYKSGLVQKSLYIQAKYQRLRFTGPRGFI 660

Query: 661 THKFRERLMRKKKEYTDVATGI 682
           THKFRERLMRKKKEYTDVATGI
Sbjct: 661 THKFRERLMRKKKEYTDVATGI 682


>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
           sapiens]
          Length = 955

 Score =  105 bits (261), Expect = 2e-22
 Identities = 81/266 (30%), Positives = 138/266 (51%), Gaps = 23/266 (8%)

Query: 381 KESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDL 440
           ++++ S ++L      P  K S    R+  + V++D     D  R +   + ER++  DL
Sbjct: 539 RKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMD-SFDEDLARPSGLLAQERKLCRDL 597

Query: 441 VAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKANYFPSPGITLHERFST 500
           V   +K + F  +F+H+ S Q+ +  P+  FAQ I+TI+H VK ++F S G+TLHERF+ 
Sbjct: 598 VHSNKKEQEFRSIFQHIQSAQS-QRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFT- 655

Query: 501 MQDIHKADVNEIPLN-SDPEIHRRIDMSLA----------ELQSKQAVIYESEQTLIKII 549
            + + +    E   N   PEIHRRID+S +          E++S +   Y++E       
Sbjct: 656 -KYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKD-- 712

Query: 550 DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKNYTTQRKDIITHKPFEVE 609
           DP DLR DIERR+K    +++  +    S    D ++SS S+  + ++ +  THK  + +
Sbjct: 713 DPVDLRLDIERRKK----HKERDLKRGKSRESVDSRDSSHSRERSAEKTE-KTHKGSKKQ 767

Query: 610 GNHRNTRVRPFKSNFRGGRCQPNYKS 635
             HR  R R  +S+    +   +YK+
Sbjct: 768 KKHRRARDRS-RSSSSSSQSSHSYKA 792


>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
           sapiens]
          Length = 869

 Score =  104 bits (260), Expect = 2e-22
 Identities = 110/448 (24%), Positives = 193/448 (43%), Gaps = 55/448 (12%)

Query: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
           G ++      F KR+ ++         G+T  R K+  + +  E  R   +W+ + +L  
Sbjct: 324 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 381

Query: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
           + +       G Q +  +E +  E +       DYR  R  +L D  + F+   + +  +
Sbjct: 382 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 430

Query: 306 EEDRKYSFQ---KGPLNRELDCFNTGRGRETQD--------GQVKEPFKPSKKDSIACTY 354
           EE  KY  +   KG  NRE D F   +  + ++           K+  K   K+S   T 
Sbjct: 431 EEGLKYKSKVSLKG--NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITV 488

Query: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
             +     +  ++K K+         K  ++      + +    +K    +  +  + +K
Sbjct: 489 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 548

Query: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
           +      D+ R AS  + +R ++  LV   +K + F  +F+H+   Q   +K T E F Q
Sbjct: 549 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 605

Query: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
            I++++H VK  YF S  +TL+ERF++ Q   KA          PEIHRRID+S + L+ 
Sbjct: 606 HIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 662

Query: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
                 ++ V  E  Q   K +  D  DLRHDI+RRRKER +   +          +  +
Sbjct: 663 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---------SKGSR 713

Query: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHR 613
            SS S+      KD   +K ++ +  H+
Sbjct: 714 ESSGSRKQEKTPKDYKEYKSYKDDSKHK 741



 Score = 36.6 bits (83), Expect = 0.079
 Identities = 107/566 (18%), Positives = 196/566 (34%), Gaps = 91/566 (16%)

Query: 53  SEKHGQSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVY-------------MYKPH--- 96
           S+   QS  R  SR +   + Y  RS + +   S + +Y             M +P+   
Sbjct: 13  SKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYR 72

Query: 97  ---RGYSPGRGDSNRRAQYMPKYS---EGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGK 150
              RGY  G G    R  Y P ++      P +   R+  P++          R R S +
Sbjct: 73  GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYR 132

Query: 151 GGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPED-- 208
             + P+ S   S R    + +  +  +R  +EK ++      ++     S  +  P+D  
Sbjct: 133 SSRSPRSS---SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTF 189

Query: 209 -----RDFRKYGHTSKRPKDV----ERYES--REP------ARNPKWKPEHSLPPYQEDT 251
                    ++  +S    D+      Y++  R P      A  P      S  P     
Sbjct: 190 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 249

Query: 252 DQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRKY 311
                 P  + H+ +  PE S +  V            +G   +S  +         R+ 
Sbjct: 250 HSAKNTPSQHSHSIQHSPERSGSGSVG-----------NGSSRYSPSQNSPIHHIPSRRS 298

Query: 312 SFQK-GPLNRELDCFNTGRGRETQDGQVKEPFKPSK-------KDSIACTYSNKNDVDLR 363
             +   P N   D  + GR     DG  +E  K  K       ++S        N  D  
Sbjct: 299 PAKTIAPQNAPRD-ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 357

Query: 364 SSNDKWKEKIKKEGDCRKE------SNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDV 417
           +S +K  EK + EG+   +      S+  S +   +    D      + R+   +V  D 
Sbjct: 358 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417

Query: 418 KKTVDTFRVASSYSTERQ----MSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQ 473
            K   +F  AS  +TE +     S   +   R+S+ F          +N + K TG   +
Sbjct: 418 GK---SFATASHRNTEEEGLKYKSKVSLKGNRESDGFR-------EEKNYKLKETGYVVE 467

Query: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQS 533
              T   + K     S  IT+ +   + + +    + ++  +  P +H+ +D        
Sbjct: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDL-FDYSPPLHKNLD------AR 520

Query: 534 KQAVIYESEQTLIKIIDPNDLRHDIE 559
           +++   E     IK+I  +  R +++
Sbjct: 521 EKSTFREESPLRIKMIASDSHRPEVK 546


>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 920

 Score =  104 bits (260), Expect = 2e-22
 Identities = 110/448 (24%), Positives = 193/448 (43%), Gaps = 55/448 (12%)

Query: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
           G ++      F KR+ ++         G+T  R K+  + +  E  R   +W+ + +L  
Sbjct: 326 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 383

Query: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
           + +       G Q +  +E +  E +       DYR  R  +L D  + F+   + +  +
Sbjct: 384 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 432

Query: 306 EEDRKYSFQ---KGPLNRELDCFNTGRGRETQD--------GQVKEPFKPSKKDSIACTY 354
           EE  KY  +   KG  NRE D F   +  + ++           K+  K   K+S   T 
Sbjct: 433 EEGLKYKSKVSLKG--NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITV 490

Query: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
             +     +  ++K K+         K  ++      + +    +K    +  +  + +K
Sbjct: 491 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 550

Query: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
           +      D+ R AS  + +R ++  LV   +K + F  +F+H+   Q   +K T E F Q
Sbjct: 551 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 607

Query: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
            I++++H VK  YF S  +TL+ERF++ Q   KA          PEIHRRID+S + L+ 
Sbjct: 608 HIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 664

Query: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
                 ++ V  E  Q   K +  D  DLRHDI+RRRKER +   +          +  +
Sbjct: 665 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---------SKGSR 715

Query: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHR 613
            SS S+      KD   +K ++ +  H+
Sbjct: 716 ESSGSRKQEKTPKDYKEYKSYKDDSKHK 743


>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
           sapiens]
          Length = 747

 Score =  103 bits (258), Expect = 4e-22
 Identities = 154/644 (23%), Positives = 255/644 (39%), Gaps = 109/644 (16%)

Query: 2   ARSRSRSPRWKHRSLSPV-PRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSK 60
           + SRS S R K RS S    R+  H +++                    R  S    ++ 
Sbjct: 4   SNSRSHSSRSKSRSQSSSRSRSRSHSRKK--------------------RYSSRSRSRTY 43

Query: 61  PRIPSRGNIYYQSYEHRSPSPNIRNS--LENVYMYKPH-RGYSPGRGDSNRRAQYMPKYS 117
            R  SR  +Y + Y       + RN+  +   Y Y+   RGY  G G    R  Y P ++
Sbjct: 44  SRSRSRDRMYSRDYRR-----DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN 98

Query: 118 EG---IPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDEL 174
                 P +   R+  P++          R R S +  + P+ S + S            
Sbjct: 99  RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS---------- 148

Query: 175 RHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPAR 234
                   K   S RRGS++ +T+ +  +  P++    K   + + PKD   ++      
Sbjct: 149 -----PYSKSPVSKRRGSQEKQTKKA--EGEPQEESPLK-SKSQEEPKDTFEHD------ 194

Query: 235 NPKWKPEHSLPPYQEDT----DQWNLGPQTYRHAERE-HPETSSATKVSYDYRHKRPKLL 289
                P  S+  + + +    D W  G   Y ++ R  H  +  AT  S         +L
Sbjct: 195 -----PSESIDEFNKSSATSGDIWP-GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPML 248

Query: 290 DGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGR--ETQDGQVKE-PFKPSK 346
                  +  +Q         +S Q  P          G  R   +Q+  +   P + S 
Sbjct: 249 STVHSAKNTPSQ-------HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSP 301

Query: 347 KDSIACTYSNKNDVDLRSS--NDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPI 404
             +IA   + +++   RSS   D   ++  K G   K      N LD  +K    + SP+
Sbjct: 302 AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKN-LDAREKSTFREESPL 360

Query: 405 NLR---KKSLTVKVDVKKT---VDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLD 458
            ++     S   +V +K     +D     +S + +R ++  LV   +K + F  +F+H+ 
Sbjct: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420

Query: 459 STQNTENKPTGE-FAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSD 517
             Q   +K T E F Q I++++H VK  YF S  +TL+ERF++ Q   KA          
Sbjct: 421 LPQ--ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKS 475

Query: 518 PEIHRRIDMSLAELQ------SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNE 569
           PEIHRRID+S + L+       ++ V  E  Q   K +  D  DLRHDI+RRRKER +  
Sbjct: 476 PEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER 535

Query: 570 DEHIFHIASAAERDDQNSSFSKNYTTQRKDIITHKPFEVEGNHR 613
            +          +  + SS S+      KD   +K ++ +  H+
Sbjct: 536 GD---------SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570


>gi|239756568 PREDICTED: similar to BCL2-associated transcription
           factor 1 [Homo sapiens]
          Length = 869

 Score =  101 bits (251), Expect = 3e-21
 Identities = 112/467 (23%), Positives = 196/467 (41%), Gaps = 55/467 (11%)

Query: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
           G ++      F KR+ ++         G+T  R K+  + +  E  R   +W+ + +L  
Sbjct: 324 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 381

Query: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
           + +       G Q +  +E +  E +       DYR  R  +L D  + F+   + +  +
Sbjct: 382 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 430

Query: 306 EEDRKYSFQ---KGPLNRELDCFNTGRG---RET-----QDGQVKEPFKPSKKDSIACTY 354
           EE  KY  +   KG  NRE D F   +    +ET     +    K+  K   K+S   T 
Sbjct: 431 EEGLKYKSKVSLKG--NRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITV 488

Query: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
             +     +  ++K K+         K  ++      + +    +K    +  +  + +K
Sbjct: 489 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 548

Query: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
           +      D+ R AS  + +R ++  LV   +K + F  +F+H+   Q   +K T E F Q
Sbjct: 549 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 605

Query: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
            I++++H VK  YF S  +TL ERF++ Q   KA          PEIHRRID+S + L+ 
Sbjct: 606 HIVSLVHHVKEQYFKSAAMTLSERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 662

Query: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
                 ++ V  E  Q   K +  D  DLRHDI+ RRKER +   +          +  +
Sbjct: 663 DTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGD---------SKGSR 713

Query: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPN 632
            S  S+      KD   +K ++ +  H+  +     S+       P+
Sbjct: 714 ESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPS 760


>gi|169218320 PREDICTED: similar to BCL2-associated transcription
           factor 1 isoform 2 [Homo sapiens]
          Length = 869

 Score =  101 bits (251), Expect = 3e-21
 Identities = 112/467 (23%), Positives = 196/467 (41%), Gaps = 55/467 (11%)

Query: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
           G ++      F KR+ ++         G+T  R K+  + +  E  R   +W+ + +L  
Sbjct: 324 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 381

Query: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
           + +       G Q +  +E +  E +       DYR  R  +L D  + F+   + +  +
Sbjct: 382 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 430

Query: 306 EEDRKYSFQ---KGPLNRELDCFNTGRG---RET-----QDGQVKEPFKPSKKDSIACTY 354
           EE  KY  +   KG  NRE D F   +    +ET     +    K+  K   K+S   T 
Sbjct: 431 EEGLKYKSKVSLKG--NRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITV 488

Query: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
             +     +  ++K K+         K  ++      + +    +K    +  +  + +K
Sbjct: 489 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 548

Query: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
           +      D+ R AS  + +R ++  LV   +K + F  +F+H+   Q   +K T E F Q
Sbjct: 549 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 605

Query: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
            I++++H VK  YF S  +TL ERF++ Q   KA          PEIHRRID+S + L+ 
Sbjct: 606 HIVSLVHHVKEQYFKSAAMTLSERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 662

Query: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
                 ++ V  E  Q   K +  D  DLRHDI+ RRKER +   +          +  +
Sbjct: 663 DTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGD---------SKGSR 713

Query: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPN 632
            S  S+      KD   +K ++ +  H+  +     S+       P+
Sbjct: 714 ESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPS 760


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 120/605 (19%), Positives = 230/605 (38%), Gaps = 123/605 (20%)

Query: 52  DSEKHGQSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSN---- 107
           D EK+ Q+K +  +  +           S     S+ + Y++KP+  YS    DS+    
Sbjct: 442 DEEKNKQNKTKTQTSDS-----------SEGKTKSVRHAYVHKPYL-YSKYYSDSDDELT 489

Query: 108 ---RRAQYMPKYSEGIPYKEHERNSYPQK-VQGGHSPDDHRVRGSGKGGKPPQRSIADSF 163
              RR     +  E +  ++  R    +K  Q        + +G G+     + S   S 
Sbjct: 490 VEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSL 549

Query: 164 RFEGKWHEDELRHQRIQEEKYSQSTRR--GSEDFETRSSFQKRYPED--RDFRKYGHTSK 219
             +    ++ L+ +++ E+K + S +R   S + E  S  +++Y ED     +   H  K
Sbjct: 550 EPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEK 609

Query: 220 R----PKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSAT 275
                 K+++   ++     P  +   SL    E+ ++  L        EREH   +S  
Sbjct: 610 EKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKL--------EREHKRRTST- 660

Query: 276 KVSYDYRHKRPKLLDGDQDFSDGRTQK-------YCKEEDRKYSFQKGPLNRELDCFNTG 328
                     P +++G Q+ +D R  K        C EE +K   QK  L  E       
Sbjct: 661 ----------PVIMEGVQEETDTRDVKRQVERSEICTEEPQK---QKSTLKNEKHL---- 703

Query: 329 RGRETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSN 388
           +  +++   +K   K   K S       K + +   S DK   K K +GDC  ++   + 
Sbjct: 704 KKDDSETPHLKSLLKKEVKSS-----KEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETE 758

Query: 389 QLDKSQKLPDVKPSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSH----DLVAVG 444
                          ++  +K L V+ +++K     +++S   TER+  H     L  +G
Sbjct: 759 ---------------LHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLG 803

Query: 445 RKSENFHPVFEHL----DSTQNTENKPTGEFAQEIITIIHQVKANY----------FPSP 490
           +  +   PV E++    ++ +   NK     + E     H+ + +               
Sbjct: 804 KDGK---PVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQH 860

Query: 491 GITLHERF-STMQDIHKADVNEIPLNSDPE--IHRRIDMSLAELQSKQAVIYES--EQTL 545
           GITL  R  S  +D    D   +  N  PE  +H+    + + L+ K  +  +S  +   
Sbjct: 861 GITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQ 920

Query: 546 IKIIDPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKNYTTQRKDIITHKP 605
           +K+++  +L+    ++               A+  + D + ++   +   QRK  +  KP
Sbjct: 921 VKVVE-TELQEGATKQ---------------ATTPKPDKEKNTEENDSEKQRKSKVEDKP 964

Query: 606 FEVEG 610
           FE  G
Sbjct: 965 FEETG 969


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 83/380 (21%), Positives = 141/380 (37%), Gaps = 59/380 (15%)

Query: 13  HRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRGNIYYQ 72
           HR++S  P N ++ K++    H      +D +R      +SEK  + K ++  R     +
Sbjct: 409 HRNVSESP-NRKNEKEKKVKDHKSNSKERDIRR------NSEKDDKYKNKVKKRAKSKSR 461

Query: 73  SYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQ 132
           S          R+S  N    K  R  S GR   N + +     S+G   +        +
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK 521

Query: 133 KVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTR-RG 191
           +++   +  DH  +   K  +   RS                R   I + K+S ++R R 
Sbjct: 522 QLESKSNEHDHS-KSKEKDRRAQSRS----------------RECDITKGKHSYNSRTRE 564

Query: 192 SEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKP-EHSLPPYQED 250
                 RS   +    DRD         R K+  RY  +E  R  + +  E   PP +  
Sbjct: 565 RSRSRDRSRRVRSRTHDRD-------RSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSR 617

Query: 251 TDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRK 310
           +       +  R +ERE  ++ +  K    YR         +Q+      ++  + E R 
Sbjct: 618 SKDRRRRRRDSRSSEREESQSRNKDK----YR---------NQESKSSHRKENSESEKRM 664

Query: 311 YSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDS-----IACTYSNKNDVDLRSS 365
           YS       +  D  ++   RE +  + + PF   K+ S      +    NK D  +RSS
Sbjct: 665 YS-------KSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS 717

Query: 366 NDKWKEKIK-KEGDCRKESN 384
            +K  +K K +E D   E N
Sbjct: 718 VEKENQKSKGQENDHVHEKN 737


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 76/346 (21%), Positives = 132/346 (38%), Gaps = 39/346 (11%)

Query: 52  DSEKHGQSKPRIPSRGNIYYQ--SYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRR 109
           + ++  + KPR  S    ++   S  H S S    +S++  +   P R  +P    S +R
Sbjct: 305 ERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQR-HSPSPRRKRTPS--PSYQR 361

Query: 110 AQYMPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKW 169
               P      PY  H  +S PQ+ Q   SP  HR     KG    +R+     R     
Sbjct: 362 TLTPPLRRSASPYPSHSLSS-PQRKQ---SPPRHRSPMREKGRHDHERTSQSHDR----- 412

Query: 170 HEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYES 229
                RH+R ++        RG  D E  S  ++ Y +D+   +     + P+D      
Sbjct: 413 -----RHERREDT-------RGKRDREKDSREEREYEQDQSSSRDHRDDREPRD---GRD 457

Query: 230 REPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL 289
           R  AR+ + + E  L   ++  D   +   +    E   P  S +T+ ++DYR +  +  
Sbjct: 458 RRDARDTRDRRE--LRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDT 515

Query: 290 DGDQDFSDGRTQKY----CKEEDRKYSFQKGPLNR---ELDCFNTGRGRETQDGQVKEPF 342
              +D     ++ Y     +EE  +   +    N    E+     GR R       ++  
Sbjct: 516 HRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGS 575

Query: 343 KPSKKDSIACTYSNKNDVDLRSSNDKWKEKIK-KEGDCRKESNSSS 387
           + S+   I    SN N  D   +   + E+ +  E D R ++  SS
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSS 621



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 71/300 (23%), Positives = 113/300 (37%), Gaps = 79/300 (26%)

Query: 171  EDELRHQRIQEEKYSQSTRRGSEDFET----RSSFQKRYPEDRDFRKYGHTSKRPKDVER 226
            E E   +R +E    +  +R  ED +     R   ++   EDR+ R  GH  ++ K   R
Sbjct: 769  ERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD-GHDERKSKKRYR 827

Query: 227  YE-SREPARNPKWKPEHSLPPYQEDTDQWNLG---------------PQTYRHAEREH-- 268
             E S  P ++PK + EHS      D+D +N G               PQ  R     H  
Sbjct: 828  NEGSPSPRQSPKRRREHS-----PDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882

Query: 269  -------------PETSSATK-----------VSYDYRHKRPKLLD----------GDQD 294
                         PE   +++            S D + ++ ++L+          G   
Sbjct: 883  EDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942

Query: 295  FSDGRTQKYCKEEDRKYS-FQKGPLNREL-DCFNTGRGR---ETQDGQVKEPFKPSKKDS 349
              D  T     +E++K +  QK P+ ++  D     RG     ++DGQV  P K  KK S
Sbjct: 943  SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002

Query: 350  I-ACTYSNKNDVDLRSSNDKWKEKIKKEG----------DCRKESNSSSNQLDKSQKLPD 398
            I      +K D D+ S  +  ++  KK G          +  +  N  +  L+ SQK  D
Sbjct: 1003 IEKKRKKSKGDSDI-SDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKED 1061


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 108/464 (23%), Positives = 170/464 (36%), Gaps = 101/464 (21%)

Query: 3    RSRSRSP---RWKHRSLSPVP-----RNAEHYKQRHSHGHYGCEYRKDPK---------R 45
            RSRSRSP   R+  RS SP        N  +  Q  +   Y   YR+ P          R
Sbjct: 721  RSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGR 780

Query: 46   PVAWR--MDSEKHGQSKPRIPSRGNIYYQSYEHRS---PSPNIRNSLENVYMYKPHRGYS 100
             V +R   + E++ + + +       YY+ Y   +   PS N  N     ++    R   
Sbjct: 781  SVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSP 840

Query: 101  PGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQG--GHSPDDH---------RVRGSG 149
              RG   RR  Y+   S       +  ++YP+K+    GH+  D+            G G
Sbjct: 841  FTRG---RREDYVGGQSHR---SRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDG 894

Query: 150  KGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQ------- 202
            KG K  +       R +G+  E  L  + ++  + S+    G E+ +T S F        
Sbjct: 895  KGNKHKKHRK----RRKGEESEGFLNPELLETSRKSREPT-GVEENKTDSLFVLPSRDDA 949

Query: 203  ---KRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQ 259
               +  P D +   +   S++ K  ER + +      K K + S    +E+  +   GPQ
Sbjct: 950  TPVRDEPMDAESITFKSVSEKDKR-ERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQ 1008

Query: 260  TYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLN 319
                 ERE    S             P +             K  KEE  K    K   +
Sbjct: 1009 EKVDGERERSPRSE------------PPI-------------KKAKEETPKTDNTKSSSS 1043

Query: 320  RELDCFNTGRGRETQDGQVKE--PFKPSKKDSIACTYS------------------NKND 359
             + D   TG  R+      KE    KP K++ +   YS                  N+ +
Sbjct: 1044 SQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKN 1103

Query: 360  VDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSP 403
              L +  +K K K +++G   K+  SSS ++ K +    VKPSP
Sbjct: 1104 KPLDNKGEKRKRKTEEKG-VDKDFESSSMKISKLEVTEIVKPSP 1146



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 107/496 (21%), Positives = 176/496 (35%), Gaps = 84/496 (16%)

Query: 18   PVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRG--NIYYQSYE 75
            P+ R   + +QR         Y        ++     + G ++ R  SR     + +SY 
Sbjct: 635  PLSREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYS 694

Query: 76   HRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKE-HERNSYPQKV 134
               P P            +  RG S      +R   Y    S   PY+  H R+  PQ  
Sbjct: 695  RSPPYP------------RRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAF 742

Query: 135  QGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRG-SE 193
            + G SP+   V         PQ          G+   +     R     Y      G S 
Sbjct: 743  R-GQSPNKRNV---------PQ----------GETEREYFNRYREVPPPYDMKAYYGRSV 782

Query: 194  DFETRSSFQK-RYPE-DRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLP------ 245
            DF  R  F+K RY E +R +R++ +           + R  A    + PE  LP      
Sbjct: 783  DF--RDPFEKERYREWERKYREW-YEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNS 839

Query: 246  PYQEDTDQWNLGPQTY--RHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKY 303
            P+     +  +G Q++  R+    +PE  SA        + + K  + +    DG+  K+
Sbjct: 840  PFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKH 899

Query: 304  CK-EEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKE----------------PFKPSK 346
             K  + RK    +G LN EL    T R      G V+E                P +   
Sbjct: 900  KKHRKRRKGEESEGFLNPEL--LETSRKSREPTG-VEENKTDSLFVLPSRDDATPVRDEP 956

Query: 347  KDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESN-----SSSNQLDKSQKLPDVKP 401
             D+ + T+ + ++ D R      ++K K +GD  K  N     S    + K  K P  K 
Sbjct: 957  MDAESITFKSVSEKDKRE-----RDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKV 1011

Query: 402  SPINLR--KKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDS 459
                 R  +    +K   ++T  T    SS S+  Q    +    RK+ +     EH ++
Sbjct: 1012 DGERERSPRSEPPIKKAKEETPKTDNTKSSSSS--QKDEKITGTPRKAHS-KSAKEHQET 1068

Query: 460  TQNTENKPTGEFAQEI 475
                E K   ++++++
Sbjct: 1069 KPVKEEKVKKDYSKDV 1084



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 67/328 (20%), Positives = 117/328 (35%), Gaps = 60/328 (18%)

Query: 103  RGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGH------SPDDHRVRGSGKGGKP-- 154
            R  SN+   + P   +   Y   E +S  ++ +         SP  ++   SG+  KP  
Sbjct: 1426 RASSNK--DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPRE 1483

Query: 155  ----PQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRD 210
                P++   DS +       D   H    + K +  T+R +E  ET+S           
Sbjct: 1484 ERDLPKKGTGDSKKSNSSPSRDRKPH----DHKATYDTKRPNE--ETKS----------- 1526

Query: 211  FRKYGHTSKRP-KDVERY--ESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAERE 267
                    K P KD E++  E+R    +   K  + L P +   ++  +  Q  +   + 
Sbjct: 1527 ------VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKP 1580

Query: 268  HPETSSATKVSYDY-RHKRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELD--- 323
             P+ S ++++S D  R       + D + SD  +    KEE+   +  K   ++ ++   
Sbjct: 1581 KPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK 1640

Query: 324  -------CFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKE 376
                       G  R             S   S + T S+ +      S D  K+K KKE
Sbjct: 1641 ESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKE 1700

Query: 377  GDCRKESNSSSN---------QLDKSQK 395
                K+               +L+KSQK
Sbjct: 1701 KKKHKKHKKHKKHKKHAGTEVELEKSQK 1728


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 108/464 (23%), Positives = 170/464 (36%), Gaps = 101/464 (21%)

Query: 3    RSRSRSP---RWKHRSLSPVP-----RNAEHYKQRHSHGHYGCEYRKDPK---------R 45
            RSRSRSP   R+  RS SP        N  +  Q  +   Y   YR+ P          R
Sbjct: 755  RSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGR 814

Query: 46   PVAWR--MDSEKHGQSKPRIPSRGNIYYQSYEHRS---PSPNIRNSLENVYMYKPHRGYS 100
             V +R   + E++ + + +       YY+ Y   +   PS N  N     ++    R   
Sbjct: 815  SVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSP 874

Query: 101  PGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQG--GHSPDDH---------RVRGSG 149
              RG   RR  Y+   S       +  ++YP+K+    GH+  D+            G G
Sbjct: 875  FTRG---RREDYVGGQSHR---SRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDG 928

Query: 150  KGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQ------- 202
            KG K  +       R +G+  E  L  + ++  + S+    G E+ +T S F        
Sbjct: 929  KGNKHKKHRK----RRKGEESEGFLNPELLETSRKSREPT-GVEENKTDSLFVLPSRDDA 983

Query: 203  ---KRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQ 259
               +  P D +   +   S++ K  ER + +      K K + S    +E+  +   GPQ
Sbjct: 984  TPVRDEPMDAESITFKSVSEKDKR-ERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQ 1042

Query: 260  TYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLN 319
                 ERE    S             P +             K  KEE  K    K   +
Sbjct: 1043 EKVDGERERSPRSE------------PPI-------------KKAKEETPKTDNTKSSSS 1077

Query: 320  RELDCFNTGRGRETQDGQVKE--PFKPSKKDSIACTYS------------------NKND 359
             + D   TG  R+      KE    KP K++ +   YS                  N+ +
Sbjct: 1078 SQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKN 1137

Query: 360  VDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSP 403
              L +  +K K K +++G   K+  SSS ++ K +    VKPSP
Sbjct: 1138 KPLDNKGEKRKRKTEEKG-VDKDFESSSMKISKLEVTEIVKPSP 1180



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 101/444 (22%), Positives = 160/444 (36%), Gaps = 75/444 (16%)

Query: 73   SYEHRSPSPNIRNSLENVYMYKPH-----RGYSPGRGDSNRRAQYMPKYSEGIPYKE-HE 126
            S   RS S +   S    Y   P      RG S      +R   Y    S   PY+  H 
Sbjct: 709  STRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHS 768

Query: 127  RNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQ 186
            R+  PQ  + G SP+   V         PQ          G+   +     R     Y  
Sbjct: 769  RSRSPQAFR-GQSPNKRNV---------PQ----------GETEREYFNRYREVPPPYDM 808

Query: 187  STRRG-SEDFETRSSFQK-RYPE-DRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHS 243
                G S DF  R  F+K RY E +R +R++ +           + R  A    + PE  
Sbjct: 809  KAYYGRSVDF--RDPFEKERYREWERKYREW-YEKYYKGYAAGAQPRPSANRENFSPERF 865

Query: 244  LP------PYQEDTDQWNLGPQTY--RHAEREHPETSSATKVSYDYRHKRPKLLDGDQDF 295
            LP      P+     +  +G Q++  R+    +PE  SA        + + K  + +   
Sbjct: 866  LPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAP 925

Query: 296  SDGRTQKYCK-EEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKE-------------- 340
             DG+  K+ K  + RK    +G LN EL    T R      G V+E              
Sbjct: 926  GDGKGNKHKKHRKRRKGEESEGFLNPEL--LETSRKSREPTG-VEENKTDSLFVLPSRDD 982

Query: 341  --PFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESN-----SSSNQLDKS 393
              P +    D+ + T+ + ++ D R      ++K K +GD  K  N     S    + K 
Sbjct: 983  ATPVRDEPMDAESITFKSVSEKDKRE-----RDKPKAKGDKTKRKNDGSAVSKKENIVKP 1037

Query: 394  QKLPDVKPSPINLR--KKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFH 451
             K P  K      R  +    +K   ++T  T    SS S+  Q    +    RK+ +  
Sbjct: 1038 AKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS--QKDEKITGTPRKAHS-K 1094

Query: 452  PVFEHLDSTQNTENKPTGEFAQEI 475
               EH ++    E K   ++++++
Sbjct: 1095 SAKEHQETKPVKEEKVKKDYSKDV 1118



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 67/328 (20%), Positives = 117/328 (35%), Gaps = 60/328 (18%)

Query: 103  RGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGH------SPDDHRVRGSGKGGKP-- 154
            R  SN+   + P   +   Y   E +S  ++ +         SP  ++   SG+  KP  
Sbjct: 1460 RASSNK--DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPRE 1517

Query: 155  ----PQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRD 210
                P++   DS +       D   H    + K +  T+R +E  ET+S           
Sbjct: 1518 ERDLPKKGTGDSKKSNSSPSRDRKPH----DHKATYDTKRPNE--ETKS----------- 1560

Query: 211  FRKYGHTSKRP-KDVERY--ESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAERE 267
                    K P KD E++  E+R    +   K  + L P +   ++  +  Q  +   + 
Sbjct: 1561 ------VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKP 1614

Query: 268  HPETSSATKVSYDY-RHKRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELD--- 323
             P+ S ++++S D  R       + D + SD  +    KEE+   +  K   ++ ++   
Sbjct: 1615 KPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK 1674

Query: 324  -------CFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKE 376
                       G  R             S   S + T S+ +      S D  K+K KKE
Sbjct: 1675 ESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKE 1734

Query: 377  GDCRKESNSSSN---------QLDKSQK 395
                K+               +L+KSQK
Sbjct: 1735 KKKHKKHKKHKKHKKHAGTEVELEKSQK 1762


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 65/313 (20%), Positives = 122/313 (38%), Gaps = 48/313 (15%)

Query: 326 NTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKE--- 382
           NT +   + + Q K PF  SK      +   KN+         ++   + E    KE   
Sbjct: 147 NTRKPNVSPEKQRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKST 206

Query: 383 -SNSSSNQLDKS-QKLPDVK-----PSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQ 435
            +++S  +L+KS Q LP +       +PI   +K +    D+ K         + S  RQ
Sbjct: 207 VADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKD-------DNQSFPRQ 259

Query: 436 MSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKA-NYFPSPGITL 494
            +  L A G        + +   S+ +T++        E +   H  +  +   SPG+T+
Sbjct: 260 RTDSLKARGAP----RGILKRNSSSSSTDS--------ETLRYNHNFEPKSKIVSPGLTI 307

Query: 495 HERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDL 554
           HER S  +  H  + N  P + +P  H R      EL     +I+  E     +++ + L
Sbjct: 308 HERISEKE--HSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRL 365

Query: 555 RHDIE---------------RRRKERLQNEDEHIFHIASAAERDDQNS-SFSKNYTTQRK 598
           ++ +E               + RK  L ++     +++ +       S SF  N      
Sbjct: 366 KNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHS 425

Query: 599 DIITHKPFEVEGN 611
           +++T +P  +E +
Sbjct: 426 EVLTARPQSMENS 438


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 19/243 (7%)

Query: 2   ARSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKP 61
           +RSRSR  R K RS S   +++ H K R S    G   R   +     R  S+K    K 
Sbjct: 194 SRSRSRHSR-KSRSRSGSSKSS-HSKSR-SRSRSGSRSRSKSRSRSQSRSRSKKE---KS 247

Query: 62  RIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKY-SEGI 120
           R PS+     +S+         ++  E       + G    R  S  +++   +  S+  
Sbjct: 248 RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307

Query: 121 PYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQ 180
             +E +R S  +      S    R R   KGG   +       R   K  +     +R +
Sbjct: 308 RVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS------RSRSKSKDKRKGRKRSR 361

Query: 181 EEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKP 240
           EE  S+S  R      ++S   ++    RD +      K+ +D +R +SR P+R+   + 
Sbjct: 362 EESRSRSRSR------SKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER 415

Query: 241 EHS 243
           EH+
Sbjct: 416 EHA 418



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 44/229 (19%), Positives = 77/229 (33%), Gaps = 11/229 (4%)

Query: 175 RHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPAR 234
           R  R+ E+K     RR      + S  + R    R  R    +SK      R  SR  +R
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227

Query: 235 N-----------PKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRH 283
           +            + K E S  P +E +   +      R   ++  E       +     
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287

Query: 284 KRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFK 343
            R       +  S  R+Q+   EE+++ S  +G    +    +  R R     + +   +
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347

Query: 344 PSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDK 392
              KD       ++ +   RS +    E+ +K G  R     SS +  K
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 87/422 (20%), Positives = 149/422 (35%), Gaps = 91/422 (21%)

Query: 23  AEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRGNIYYQSYEHRSPSPN 82
           AEH  Q   H  +G E             D+E   + +  +PS     ++S+ H+    +
Sbjct: 125 AEHGGQARGHRGHGSE-------------DTEDSAEHRHHLPS-----HRSHSHQDEDED 166

Query: 83  IRNSLENVY--MYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGHSP 140
              S E+ +  +   HRG+  G  D            EG   +E E        + GH  
Sbjct: 167 EVVSSEHHHHILRHGHRGHD-GEDD------------EGEEEEEEEEEEEEASTEYGHQA 213

Query: 141 DDHRVRGSGKGG--KPPQRSIADSFRFEGKWHED-----------------ELRHQRI-- 179
             HR  GS +             S R +G   +D                 E RHQ    
Sbjct: 214 HRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRH 273

Query: 180 ------QEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPA 233
                 ++E  S            RS  +    +D    +YGH + R +D  + E    +
Sbjct: 274 QGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVS 333

Query: 234 -RNPKWKPEHSLPPYQED-------TDQWNLGPQTYRHA---EREHPETSSATKVSYDYR 282
             +    P+H    ++++       T++W+ GPQ   H    E E  E  +     Y   
Sbjct: 334 GEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVAS 393

Query: 283 HKRPKLLDGDQDFSD--------GRTQKYCKEEDRKYSFQKG---PLNREL-DCFNTGRG 330
           H+       ++DF D            +  +EED + S + G   P +R+      TG G
Sbjct: 394 HQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHG 453

Query: 331 RETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQL 390
              Q G +KE        ++      K+   LR  + + +++ +++    +E + SS Q 
Sbjct: 454 ---QRGSIKEMSHHPPGHTVV-----KDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQG 505

Query: 391 DK 392
           +K
Sbjct: 506 EK 507


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 65/319 (20%), Positives = 117/319 (36%), Gaps = 49/319 (15%)

Query: 3   RSRSRSPRWKHRSLSPV-----PRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHG 57
           R RSRSPR   RSLSP       R+  H+++ H    +  E  ++ +R    R++ E   
Sbjct: 257 RRRSRSPR---RSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQ---RLEREAKE 310

Query: 58  QSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYS 117
           + K R  SR     +  E R      R           HR  S  R     R        
Sbjct: 311 REKERRRSRS--IDRGLERRRSRSRER-----------HRSRSRSRDRKGDR-------- 349

Query: 118 EGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQ 177
                ++ +R    +  +G     D+      +  K  +RS   S     +   +E +H+
Sbjct: 350 -----RDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHK 404

Query: 178 RIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPK 237
             ++++  +  +R S+  +  S  + R  + R   +  +  KR +   + +S +     K
Sbjct: 405 EDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESK 464

Query: 238 WKP-EHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFS 296
            K  + S    Q  TD         +  +REH  +   ++     +  R K     +D S
Sbjct: 465 EKSNKRSRSGSQGRTD------SVEKSKKREHSPSKEKSR-----KRSRSKERSHKRDHS 513

Query: 297 DGRTQKYCKEEDRKYSFQK 315
           D + Q    +  R  S ++
Sbjct: 514 DSKDQSDKHDRRRSQSIEQ 532


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 62/300 (20%), Positives = 116/300 (38%), Gaps = 48/300 (16%)

Query: 339 KEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKE----SNSSSNQLDKS- 393
           K PF  SK      +   KN+         ++   + E    KE    +++S  +L+KS 
Sbjct: 159 KNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSK 218

Query: 394 QKLPDVK-----PSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSE 448
           Q LP +       +PI   +K +    D+ K         + S  RQ +  L A G    
Sbjct: 219 QTLPGLSNGSQIKAPIPKARKMIYKSTDLNKD-------DNQSFPRQRTDSLKARGAP-- 269

Query: 449 NFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKA-NYFPSPGITLHERFSTMQDIHKA 507
               + +   S+ +T++        E +   H  +  +   SPG+T+HER S  +  H  
Sbjct: 270 --RGILKRNSSSSSTDS--------ETLRYNHNFEPKSKIVSPGLTIHERISEKE--HSL 317

Query: 508 DVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDLRHDIE-------- 559
           + N  P + +P  H R      EL     +I+  E     +++ + L++ +E        
Sbjct: 318 EDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEF 377

Query: 560 -------RRRKERLQNEDEHIFHIASAAERDDQNS-SFSKNYTTQRKDIITHKPFEVEGN 611
                  + RK  L ++     +++ +       S SF  N      +++T +P  +E +
Sbjct: 378 QSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENS 437


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 62/300 (20%), Positives = 116/300 (38%), Gaps = 48/300 (16%)

Query: 339 KEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKE----SNSSSNQLDKS- 393
           K PF  SK      +   KN+         ++   + E    KE    +++S  +L+KS 
Sbjct: 159 KNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSK 218

Query: 394 QKLPDVK-----PSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSE 448
           Q LP +       +PI   +K +    D+ K         + S  RQ +  L A G    
Sbjct: 219 QTLPGLSNGSQIKAPIPKARKMIYKSTDLNKD-------DNQSFPRQRTDSLKARGAP-- 269

Query: 449 NFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKA-NYFPSPGITLHERFSTMQDIHKA 507
               + +   S+ +T++        E +   H  +  +   SPG+T+HER S  +  H  
Sbjct: 270 --RGILKRNSSSSSTDS--------ETLRYNHNFEPKSKIVSPGLTIHERISEKE--HSL 317

Query: 508 DVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDLRHDIE-------- 559
           + N  P + +P  H R      EL     +I+  E     +++ + L++ +E        
Sbjct: 318 EDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEF 377

Query: 560 -------RRRKERLQNEDEHIFHIASAAERDDQNS-SFSKNYTTQRKDIITHKPFEVEGN 611
                  + RK  L ++     +++ +       S SF  N      +++T +P  +E +
Sbjct: 378 QSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENS 437


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 39/177 (22%), Positives = 68/177 (38%), Gaps = 18/177 (10%)

Query: 106  SNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRS--IADSF 163
            S R  +    + + +    H  + +      G S   H   GS    +  ++     D  
Sbjct: 1171 SRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGS 1230

Query: 164  RFEGKWHE------DELRHQRIQEEKYSQS-TRRGSEDFETRSSFQKRYPEDRDFRKYGH 216
            R  G  H       D  RH ++ +E+ S S T R      ++ S  +R+ +D + R  G 
Sbjct: 1231 RHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSE-RLSGS 1289

Query: 217  TSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSS 273
             S+      R +SR+ +R+P +        +QED         + R +   H E+SS
Sbjct: 1290 ASRNHHGSSREQSRDGSRHPGF--------HQEDRASHGHSADSSRQSGTHHTESSS 1338



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 49/241 (20%), Positives = 87/241 (36%), Gaps = 32/241 (13%)

Query: 56   HGQSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPK 115
            HGQ+ P    R    ++   + S     ++  + +      RG+ PG     R+  Y   
Sbjct: 1455 HGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTI------RGH-PGSSRGGRQGSY--- 1504

Query: 116  YSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPP--QRSIADSFRFEGKWHED- 172
            + + +    H    +      G S   H   G     +    +    D  R  G  H + 
Sbjct: 1505 HEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEP 1564

Query: 173  -----ELRHQRIQEEKYS---QSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDV 224
                   RH ++ + + +    S R+GS   + R S  + + ED + R+    S+     
Sbjct: 1565 STRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDS--EGHSEDSE-RRSESASRNHYGS 1621

Query: 225  ERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHK 284
             R +SR  +RNP+         +QED        ++ R +   H ETSS  + +      
Sbjct: 1622 AREQSRHGSRNPR--------SHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQA 1673

Query: 285  R 285
            R
Sbjct: 1674 R 1674



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 76/341 (22%), Positives = 120/341 (35%), Gaps = 54/341 (15%)

Query: 21   RNAEHYKQRHSH-GHYGCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRGNIYYQSYEHRSP 79
            R   H++Q     GH G  +     +    R D+  HGQS  R  SR     Q+ + +  
Sbjct: 1176 RQGSHHEQSVDRSGHSGSHHSHTTSQG---RSDAS-HGQSGSRSASR-----QTRKDKQS 1226

Query: 80   SPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQG-GH 138
                R+S       + H   S    DS+R +Q   + S G     H+ +S  Q      H
Sbjct: 1227 GDGSRHSGS-----RHHEAAS--WADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERH 1279

Query: 139  SPDDHRVRGSGK---GGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDF 195
            S D  R+ GS      G   ++S  D  R  G   ED   H       +S  + R S   
Sbjct: 1280 SDDSERLSGSASRNHHGSSREQS-RDGSRHPGFHQEDRASH------GHSADSSRQSGTH 1332

Query: 196  ETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESR-----EPARNPKWKPEHSLPPYQED 250
             T SS   +           H   R    ER+ SR     + +R+       +    ++ 
Sbjct: 1333 HTESSSHGQAVS-------SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDS 1385

Query: 251  TDQWNLGPQTYR---HAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKY---- 303
              + + G Q      H+E    ++ SA   +  ++    +   G    S GR++ +    
Sbjct: 1386 GHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQV 1445

Query: 304  -CKEEDRKYSFQKGPL------NRELDCFNTGRGRETQDGQ 337
               E+      Q  P       +R     N+ R   +QDGQ
Sbjct: 1446 SSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQ 1486



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 37/193 (19%), Positives = 65/193 (33%), Gaps = 18/193 (9%)

Query: 102  GRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIAD 161
            G   S+RR +    Y + +    H  + +      G S       GS    +  +     
Sbjct: 3436 GHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQS 3495

Query: 162  --------SFRFEGKWHEDELRH-QRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFR 212
                    S   E     D  RH Q  Q +     T R      ++ S  + + ED + R
Sbjct: 3496 GDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE-R 3554

Query: 213  KYGHTSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETS 272
              G  S+  +   + +SR+ +R+P          + ED        ++ R +   H E S
Sbjct: 3555 WSGSASRNHRGSAQEQSRDGSRHP--------TSHHEDRAGHGHSAESSRQSGTHHAENS 3606

Query: 273  SATKVSYDYRHKR 285
            S  + +  +   R
Sbjct: 3607 SGGQAASSHEQAR 3619


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 91/470 (19%), Positives = 163/470 (34%), Gaps = 97/470 (20%)

Query: 125  HERNSYPQKVQGGHSPDDHRVRGSGKGGK------PPQRSIADSFRFEGKWHEDELRHQR 178
            HER ++ Q +      D+ R   +G G        PP   +           EDE+    
Sbjct: 1241 HERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVP--- 1297

Query: 179  IQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKW 238
              +E  +Q   R  E+F+                      +   D  R E+R P R P+ 
Sbjct: 1298 -DDETVNQMIARHEEEFDL-------------------FMRMDLDRRREEARNPKRKPRL 1337

Query: 239  KPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDG 298
              E  LP +    D            ER   E           RH++      + D+SD 
Sbjct: 1338 MEEDELPSWIIKDD---------AEVERLTCEEEEEKMFGRGSRHRK------EVDYSDS 1382

Query: 299  RTQKYCKEE-------DRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIA 351
             T+K   ++       D   S  +G   +    F T   +  ++G ++E  +  ++    
Sbjct: 1383 LTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK-- 1440

Query: 352  CTYSNKNDVDLRSSNDKWKEKIK-KEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKS 410
             +   K D D  SS      + + K+ + +K+        +K      + P+P NL KK 
Sbjct: 1441 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEK------LSPNPPNLTKK- 1493

Query: 411  LTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVG------------RKSENFHPVFEHLD 458
                  +KK VD        S+ RQ+S   + +             RK  +F  + E + 
Sbjct: 1494 ------MKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERI- 1546

Query: 459  STQNTENKPTGEFAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDP 518
              +N + +   +  ++++ +     A  F   G  ++E    +Q +  +   +I    D 
Sbjct: 1547 --RNHKYRSLNDLEKDVMLLCQ--NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1602

Query: 519  EIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDLRHDIERRRKERLQN 568
            E     +    E +       ESE   +K+         I+  RKE+ Q+
Sbjct: 1603 EGEESEEEEEGEEEGS-----ESESRSVKV--------KIKLGRKEKAQD 1639


>gi|34098946 nuclease sensitive element binding protein 1 [Homo
           sapiens]
          Length = 324

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 38/191 (19%), Positives = 82/191 (42%), Gaps = 16/191 (8%)

Query: 63  IPSRGNIYYQSYEH-------RSPSPNIRNSLENVYMYKPHRGY-SPGRGDSNRRAQY-- 112
           +P +G+ Y     H       R P  N + + +N    + + G  S   G + +R  Y  
Sbjct: 131 VPVQGSKYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRR 190

Query: 113 --MPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWH 170
              P Y    PY    + S P  VQG    +    +G+G+ G+P ++++   +R   ++ 
Sbjct: 191 RRFPPYYMRRPYGRRPQYSNPP-VQG-EVMEGADNQGAGEQGRPVRQNMYRGYR--PRFR 246

Query: 171 EDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESR 230
               R ++ +E+   +      ++ + +   Q+RY  + ++R+    + +P+D +  ++ 
Sbjct: 247 RGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDGKETKAA 306

Query: 231 EPARNPKWKPE 241
           +P       PE
Sbjct: 307 DPPAENSSAPE 317


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 1616

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 54/237 (22%), Positives = 86/237 (36%), Gaps = 33/237 (13%)

Query: 22  NAEHYKQRHSHGHY--GCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRGNIYYQSYEHRSP 79
           N  H   R  +G    G + R + +R      +S     SKPR P R     ++    SP
Sbjct: 94  NGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSP 153

Query: 80  SPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGHS 139
           SP I            H    P +                 P +E ER    + ++    
Sbjct: 154 SPRITRKSTRQTTITSHFAKGPAKRK---------------PQEESERAKSDESIKEEDK 198

Query: 140 PDD---HRVRGSGKGGKP-----PQRSIADSFRFEGKWHEDELRHQRIQ---EEKYSQST 188
             D    RV    +  +P     P+R+ + + R E +   DE   +R++   +E   +  
Sbjct: 199 DQDEKRRRVTSRERVARPLPAEEPERAKSGT-RTEKEEERDEKEEKRLRSQTKEPTPKQK 257

Query: 189 RRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDV---ERYESREPAR-NPKWKPE 241
            +   D E R+  Q    ED D +       +PKD+    R E +EP + NP+   E
Sbjct: 258 LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDE 314


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 60/251 (23%), Positives = 90/251 (35%), Gaps = 31/251 (12%)

Query: 4   SRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAW----------RMDS 53
           SRSRSP+W+        R+A+ + +  S    G    + P+RP  W          R  S
Sbjct: 506 SRSRSPQWRR------SRSAQRWGRSRSPQRRG--RSRSPQRP-GWSRSRNTQRRGRSRS 556

Query: 54  EKHGQSKPRIP-----SRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPG-RGDSN 107
            + G+S  R P     SR     +    RS +P  R S       +  R  +P  RG S 
Sbjct: 557 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR 616

Query: 108 RRAQYMPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEG 167
            R     +     P +   R+  P +  G         RG  +   P +R  + S     
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR 676

Query: 168 KWHEDELRHQRIQEEKYSQSTRRG---SEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDV 224
           +      R    +    S++ RRG   S     R     R P+ R   + G +S+R K+ 
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRG--RSGSSSER-KNK 733

Query: 225 ERYESREPARN 235
            R   R    N
Sbjct: 734 SRTSQRRSRSN 744



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 39/169 (23%), Positives = 62/169 (36%), Gaps = 15/169 (8%)

Query: 3   RSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPR 62
           RSRSR+P  + RS S  P       +  +    G    + P+R  +      + G+S  R
Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716

Query: 63  IPSRGNIYYQSYEHRSPS-PNIRNSLENV--------YMYKPHRGYSPGRGDSNRRAQYM 113
            P R      S E ++ S  + R S  N            +  R  S  R  +  R    
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776

Query: 114 PKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADS 162
              S   P  + +  + P++ + G S      +   K   PP+RS + S
Sbjct: 777 RSLSGSSPCPKQKSQTPPRRSRSGSS------QPKAKSRTPPRRSRSSS 819



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 69/294 (23%), Positives = 99/294 (33%), Gaps = 38/294 (12%)

Query: 3   RSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPR 62
           RSRSR+P  + RS S  P       +R S        R   + P        + G+S+ R
Sbjct: 572 RSRSRTPARRGRSRSRTP------ARRRSRSRTPTRRRSRSRTPA-------RRGRSRSR 618

Query: 63  IPSRGNIYYQS---YEHRSPSPNIRNSLENVYMYKPHRGYS-------PGRGDSNRRAQY 112
            P+R     +S      RS SP  R S  +       RG S        GR  S   A+ 
Sbjct: 619 TPARRRSRTRSPVRRRSRSRSP-ARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR 677

Query: 113 MPKYSEGIPYKE-HERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQR----SIADSFRFEG 167
             +     P +    R+  P++   G S     VR      + PQR      +   + + 
Sbjct: 678 SGRSRSRTPARRGRSRSRTPRR---GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734

Query: 168 KWHEDELRHQRIQEEKYSQ-STRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVER 226
           +  +   R     E K S+ S+RR       RS  + R    R         K+      
Sbjct: 735 RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794

Query: 227 YESREPARNPKWK----PEHSLPPYQEDTDQWNLGPQTYRHAERE-HPETSSAT 275
             SR  +  PK K    P  S         Q +  P    H+    HP+  S T
Sbjct: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 80/413 (19%), Positives = 156/413 (37%), Gaps = 56/413 (13%)

Query: 193 EDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTD 252
           +DFE R   +++  E+          +R  D E   +RE  R  +   +  L   QE+  
Sbjct: 2   DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRAR---QERLRQKQEEES 58

Query: 253 QWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFS--------DGRTQKYC 304
              +  Q   +A+   P+  + T  +          ++GD + +        + R QK  
Sbjct: 59  LGQVTDQVEVNAQNSVPDEEAKTTTTNTQ-------VEGDDEAAFLERLARREERRQKRL 111

Query: 305 KEE-DRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKK----------DSIACT 353
           +E  +R+  F     +  L   +     +T + +  E  + S+           +++  +
Sbjct: 112 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKS 171

Query: 354 YSNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLD--------KSQKLPDVKPSPIN 405
           Y   +  D   +  + KEK ++E +  K  +   NQ +        K +KL + KP+   
Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPT--- 228

Query: 406 LRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTEN 465
             KK       +KK  +      S+   ++   ++     KS+N   +   L  T+NT +
Sbjct: 229 -FKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV-----KSQNGEFMTHKLKHTENTFS 282

Query: 466 KPTGEFAQEIITI--IHQVKA-----NYFPSPGITLHERFSTMQDIHKADVNEIPLNSDP 518
           +P G  + +        QV+A           G T  E F  ++   +    E+      
Sbjct: 283 RPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKK 342

Query: 519 EIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDLRHDIERRRKERLQNEDE 571
              RR  +   E + KQ    E+++ L +  +   L+ +IERRR E  +   +
Sbjct: 343 REERRKVLEEEEQRRKQE---EADRKLREEEEKRRLKEEIERRRAEAAEKRQK 392


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 92/462 (19%), Positives = 160/462 (34%), Gaps = 113/462 (24%)

Query: 125  HERNSYPQKVQGGHSPDDHRVRGSGKGGK------PPQRSIADSFRFEGKWHEDELRHQR 178
            HER ++ Q +      D+ R   +G G        PP   +           EDE+    
Sbjct: 1241 HERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVP--- 1297

Query: 179  IQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKW 238
              +E  +Q   R  E+F+                      +   D  R E+R P R P+ 
Sbjct: 1298 -DDETVNQMIARHEEEFDL-------------------FMRMDLDRRREEARNPKRKPRL 1337

Query: 239  KPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDG 298
              E  LP +    D            ER   E           RH++      + D+SD 
Sbjct: 1338 MEEDELPSWIIKDD---------AEVERLTCEEEEEKMFGRGSRHRK------EVDYSDS 1382

Query: 299  RTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKN 358
             T+K   +     + ++G L  E++          ++ + K+  +  K+DS A + +   
Sbjct: 1383 LTEKQWLK-----AIEEGTL-EEIE----------EEVRQKKSSRKRKRDSDAGSSTPTT 1426

Query: 359  DVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVK 418
                R  +D+ K K KK G    E                + P+P NL KK       +K
Sbjct: 1427 STRSRDKDDESK-KQKKRGRPPAEK---------------LSPNPPNLTKK-------MK 1463

Query: 419  KTVDTFRVASSYSTERQMSHDLVAVG------------RKSENFHPVFEHLDSTQNTENK 466
            K VD        S+ RQ+S   + +             RK  +F  + E +   +N + +
Sbjct: 1464 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERI---RNHKYR 1520

Query: 467  PTGEFAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDM 526
               +  ++++ +     A  F   G  ++E    +Q +  +   +I    D E     + 
Sbjct: 1521 SLNDLEKDVMLLCQ--NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1578

Query: 527  SLAELQSKQAVIYESEQTLIKIIDPNDLRHDIERRRKERLQN 568
               E +       ESE   +K+         I+  RKE+ Q+
Sbjct: 1579 EEGEEEGS-----ESESRSVKV--------KIKLGRKEKAQD 1607


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 92/462 (19%), Positives = 160/462 (34%), Gaps = 113/462 (24%)

Query: 125  HERNSYPQKVQGGHSPDDHRVRGSGKGGK------PPQRSIADSFRFEGKWHEDELRHQR 178
            HER ++ Q +      D+ R   +G G        PP   +           EDE+    
Sbjct: 1241 HERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVP--- 1297

Query: 179  IQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKW 238
              +E  +Q   R  E+F+                      +   D  R E+R P R P+ 
Sbjct: 1298 -DDETVNQMIARHEEEFDL-------------------FMRMDLDRRREEARNPKRKPRL 1337

Query: 239  KPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDG 298
              E  LP +    D            ER   E           RH++      + D+SD 
Sbjct: 1338 MEEDELPSWIIKDD---------AEVERLTCEEEEEKMFGRGSRHRK------EVDYSDS 1382

Query: 299  RTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKN 358
             T+K   +     + ++G L  E++          ++ + K+  +  K+DS A + +   
Sbjct: 1383 LTEKQWLK-----AIEEGTL-EEIE----------EEVRQKKSSRKRKRDSDAGSSTPTT 1426

Query: 359  DVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVK 418
                R  +D+ K K KK G    E                + P+P NL KK       +K
Sbjct: 1427 STRSRDKDDESK-KQKKRGRPPAEK---------------LSPNPPNLTKK-------MK 1463

Query: 419  KTVDTFRVASSYSTERQMSHDLVAVG------------RKSENFHPVFEHLDSTQNTENK 466
            K VD        S+ RQ+S   + +             RK  +F  + E +   +N + +
Sbjct: 1464 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERI---RNHKYR 1520

Query: 467  PTGEFAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDM 526
               +  ++++ +     A  F   G  ++E    +Q +  +   +I    D E     + 
Sbjct: 1521 SLNDLEKDVMLLCQ--NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1578

Query: 527  SLAELQSKQAVIYESEQTLIKIIDPNDLRHDIERRRKERLQN 568
               E +       ESE   +K+         I+  RKE+ Q+
Sbjct: 1579 EEGEEEGS-----ESESRSVKV--------KIKLGRKEKAQD 1607


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 49/218 (22%), Positives = 83/218 (38%), Gaps = 10/218 (4%)

Query: 169 WHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYE 228
           W  +    +R  E +      R SE  + R   +KR  E    RK     K  K   + E
Sbjct: 34  WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93

Query: 229 SRE--PARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRP 286
            RE    R  K   E      ++  ++   G  +    ERE  E     +     R K  
Sbjct: 94  ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153

Query: 287 KLLDGDQDFSDGRTQKYC--KEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKP 344
           +  + ++     R +K    KEE+RK   +K    RE +     + RE ++ + ++  + 
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213

Query: 345 SKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKE 382
            K++        K     R +N + KE+ K+E   RK+
Sbjct: 214 KKEE------RKKERQKDRQTNWREKERGKRERKERKK 245


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 32/152 (21%), Positives = 61/152 (40%), Gaps = 13/152 (8%)

Query: 147 GSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRY- 205
           G G    PP    A   R+E +        +R  E        RG+  F+    + + Y 
Sbjct: 111 GGGPAYGPPPSLHAREGRYERRLDGASDNRERAYEHSAYGHHERGTGGFDRTRHYDQDYY 170

Query: 206 --PEDRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLPP------YQEDTDQWNLG 257
             P +R  +   + + R +   R+++ +P   P+ + + +LP       Y++D  +   G
Sbjct: 171 RDPRERTLQHGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRG 230

Query: 258 PQTYRHAEREHPETSSATKVSYDYRHKRPKLL 289
               R  ER +  + S +  S   R++ P+ L
Sbjct: 231 ----RRPERNYQHSRSRSPHSSQSRNQSPQRL 258



 Score = 33.1 bits (74), Expect = 0.87
 Identities = 45/220 (20%), Positives = 82/220 (37%), Gaps = 29/220 (13%)

Query: 165 FEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDV 224
           +E ++++D   ++  + + Y Q  R  S     R   ++R+  DRD        +RP  +
Sbjct: 669 YESRYYDDPREYRDYRNDPYEQDIREYSYRQRERERERERFESDRD----RDHERRP--I 722

Query: 225 ERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHK 284
           ER +S    R P+        P Q +    +   + Y  +       SS +   Y+   K
Sbjct: 723 ERSQSPVHLRRPQ---SPGASPSQAERLPSDSERRLYSRSSDRSGSCSSLSPPRYEKLDK 779

Query: 285 RPKLLDGDQDFSDGRTQKYCKEE--DRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPF 342
                         R ++Y K E  D++ +F    + RE       +  + +  + K   
Sbjct: 780 -------------SRLERYTKNEKTDKERTFDPERVERERRLIRKEKVEKDKTDKQKRKG 826

Query: 343 KPSKKDSIACTYSNKNDVDL-----RSSNDKWKEKIKKEG 377
           K     S +     +N+ +      RS N   +EK  KEG
Sbjct: 827 KVHSPSSQSSETDQENEREQSPEKPRSCNKLSREKADKEG 866


>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
           sapiens]
          Length = 558

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 50/234 (21%), Positives = 89/234 (38%), Gaps = 61/234 (26%)

Query: 170 HEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYES 229
           H     H R   E+   STR  ++   T    +KR  ED+      H  K+ +D E + +
Sbjct: 282 HHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKR--EDQ------HQQKQSRDQENHYT 333

Query: 230 REPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL 289
               R  +    H    +++    W       RH + + P        + D R +  ++ 
Sbjct: 334 DRDYRKERDSHRHREASHRD--SHWK------RHEQEDKPR-------ARDQRERSDRVW 378

Query: 290 DGDQDFSDGRTQKYC---KEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSK 346
             ++D      +KY    +E DR+ + Q  P         + +G + +  + KE     +
Sbjct: 379 KREKD-----REKYSQREQERDRQQNDQNRP---------SEKGEKEEKSKAKEEHMKVR 424

Query: 347 KDSIACTYSNKNDVDLRSSNDKWKEKIKKE--------GDCRKESNSSSNQLDK 392
           K+     Y N         NDK++++ K+E           RKES+ +S   DK
Sbjct: 425 KE----RYEN---------NDKYRDREKREVGVQSSERNQDRKESSPNSRAKDK 465


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 46/220 (20%), Positives = 87/220 (39%), Gaps = 18/220 (8%)

Query: 141 DDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSS 200
           DDH +     G    + ++ +      K  E+  R +R+++EK  +  R    + E    
Sbjct: 209 DDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREER 268

Query: 201 FQKRYPEDRDFRKY----GHTSKRPKDVERYESREPARNPKWKPEHSLPPYQE---DTDQ 253
            +KR  E+ +  K         KR +   R+ SR   R      +H     +E      +
Sbjct: 269 ERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR 328

Query: 254 WNLGPQTYRHAEREHPETS-----SATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEED 308
                +++  +ER+H   S     S ++    Y+H R K  D +QD      +K    +D
Sbjct: 329 DRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKH-RSKSRDREQDRKSKEKEKR-GSDD 386

Query: 309 RKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKD 348
           +K S + G   ++ +  NT    E+++   K     + +D
Sbjct: 387 KKSSVKSGSREKQSEDTNT----ESKESDTKNEVNGTSED 422


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,684,055
Number of Sequences: 37866
Number of extensions: 1525693
Number of successful extensions: 4066
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 3850
Number of HSP's gapped (non-prelim): 347
length of query: 682
length of database: 18,247,518
effective HSP length: 109
effective length of query: 573
effective length of database: 14,120,124
effective search space: 8090831052
effective search space used: 8090831052
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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