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Search of human proteins with 224591430
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]
(379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224591430 Ly1 antibody reactive homolog [Homo sapiens] 773 0.0
gi|8923398 Ly1 antibody reactive homolog [Homo sapiens] 773 0.0
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 67 3e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 64 3e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 61 2e-09
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 57 3e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 57 4e-08
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 57 4e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 55 1e-07
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 54 2e-07
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 54 2e-07
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 54 2e-07
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 54 2e-07
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 53 4e-07
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 53 4e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 53 5e-07
gi|52426743 cisplatin resistance-associated overexpressed protei... 53 5e-07
gi|19923485 cisplatin resistance-associated overexpressed protei... 53 5e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 52 7e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 52 7e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 52 7e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 52 7e-07
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 52 9e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 1e-06
gi|34878777 ring finger protein 20 [Homo sapiens] 52 1e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 2e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 51 2e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 51 2e-06
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 51 2e-06
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 51 2e-06
>gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]
Length = 379
Score = 773 bits (1995), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG 60
MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG
Sbjct: 1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG 60
Query: 61 KGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKN 120
KGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKN
Sbjct: 61 KGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKN 120
Query: 121 SLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQ 180
SLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQ
Sbjct: 121 SLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQ 180
Query: 181 QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE 240
QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE
Sbjct: 181 QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE 240
Query: 241 ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED 300
ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED
Sbjct: 241 ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED 300
Query: 301 DEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNK 360
DEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNK
Sbjct: 301 DEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNK 360
Query: 361 KISKNPTFKLLKDKVKLVK 379
KISKNPTFKLLKDKVKLVK
Sbjct: 361 KISKNPTFKLLKDKVKLVK 379
>gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]
Length = 379
Score = 773 bits (1995), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG 60
MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG
Sbjct: 1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG 60
Query: 61 KGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKN 120
KGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKN
Sbjct: 61 KGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKN 120
Query: 121 SLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQ 180
SLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQ
Sbjct: 121 SLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQ 180
Query: 181 QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE 240
QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE
Sbjct: 181 QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE 240
Query: 241 ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED 300
ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED
Sbjct: 241 ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED 300
Query: 301 DEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNK 360
DEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNK
Sbjct: 301 DEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNK 360
Query: 361 KISKNPTFKLLKDKVKLVK 379
KISKNPTFKLLKDKVKLVK
Sbjct: 361 KISKNPTFKLLKDKVKLVK 379
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 67.0 bits (162), Expect = 3e-11
Identities = 36/145 (24%), Positives = 78/145 (53%), Gaps = 4/145 (2%)
Query: 164 EISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKR 223
EI T+ K +++ ++ ++ KR+R+ E+++KR+R KKE K E +E +K ++
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 224 KKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSK 283
K+ +E + + ++ + + K+++RK+ EE + +R+R+ E E + +
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK----ERERKKEEREKERE 159
Query: 284 KKKMKLPEHPEGGEPEDDEAPAKGK 308
+K+ K E + GE E++ + K
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERK 184
Score = 56.6 bits (135), Expect = 4e-08
Identities = 36/127 (28%), Positives = 67/127 (52%), Gaps = 15/127 (11%)
Query: 179 EQQGEVKKNKRERK-----------EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQ 227
E++GE KK +RERK EE++K++K+EKKE + +E ++ ++RK+ +
Sbjct: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE-RGRTSKEGKERERKEERKREE 143
Query: 228 EADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
+ E EE + ++ +KK++RK +EE R +++R+ E +KK+
Sbjct: 144 RKERERKKEEREKERE---RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
Query: 288 KLPEHPE 294
+ E E
Sbjct: 201 ERKERRE 207
Score = 54.3 bits (129), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Query: 173 KVKDAVEQQGEVKKNK-RERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADL 231
K K+ E+ K+ K RERKEER+++ ++E++ K E +E R ++ K+ +K
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK------ 169
Query: 232 EAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
+ G +E +R K+++ RK+ E E + ++K R + E +++K
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Score = 48.9 bits (115), Expect = 7e-06
Identities = 33/145 (22%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
Query: 144 EPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKRE- 202
E NKE +++ T + + E++ E +K + +KEER+K+R+R+
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Query: 203 --KKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSAS 260
K+E K +E R +K +K +K +E + + +E +R K++K++++
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE--RERKERRERKKERKKKEERKK 220
Query: 261 EEEARVGAGKRKRRHSEVETDSKKK 285
E + R++ + E +KK
Sbjct: 221 ERQKDRQTNWREKERGKRERKERKK 245
Score = 38.1 bits (87), Expect = 0.013
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 139 EASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKE--ERQ 196
E E KE+ +R V E K + K E+ + +K +RERKE ER+
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKR--ERNRKERKKERERKERRERK 209
Query: 197 KKRKREKKELKLENHQENSRNQKPKKRKKGQEAD 230
K+RK+ K+E K E ++ N + K+R K + +
Sbjct: 210 KERKK-KEERKKERQKDRQTNWREKERGKRERKE 242
Score = 30.4 bits (67), Expect = 2.7
Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 215 SRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRR 274
S KP + Q E E G + S++KK+R++ + R KR+R
Sbjct: 23 SHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERG 82
Query: 275 HSEVETDSK------KKKMKLPEHPEGGEPE 299
E + + K KK+ + E+ EG E E
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKE 113
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 63.5 bits (153), Expect = 3e-10
Identities = 34/108 (31%), Positives = 66/108 (61%), Gaps = 7/108 (6%)
Query: 173 KVKDAVEQQGEVKKNKRERKEERQKKRKR---EKKELKLENHQENSRNQKPKKRKKGQEA 229
+ ++ E++G+ K+ ++E+++E++KK+K EK++ K E ++ R +K KK ++ +E
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 230 DLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSE 277
+ E EE E G+R KKKK+R+ EEE + K++RR ++
Sbjct: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK----KKRRRKTK 121
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 12/116 (10%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
KK K++ EE ++ + E++E K +E + ++ +K KK + + E E+ E
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 245 AGKRSKKK------------KQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
KR KKK ++ K+ +EE R K+KRR E E + KKK+ +
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
KK + E EE ++ + E+KE K + ++ R +K KK KK +E + EE +
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK-KKTKETEKRKEKEEEEKKR-- 62
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPE 294
KR +KKK+ ++ EEE K + E KKKK + E E
Sbjct: 63 --KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 47.0 bits (110), Expect = 3e-05
Identities = 29/115 (25%), Positives = 54/115 (46%)
Query: 221 KKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVET 280
KK+KK +E + EE E GKR +K+K+++ +++ KRK + E +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 281 DSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKK 335
+K+K K E E E++E + + +G + K+ E +K +K+
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 144 EPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERK---EERQKKRK 200
E KE ++ E K ++ + E++ + +K KR++K EER+++ +
Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 201 REKKELKLENHQENSRNQKPKKRKKGQEAD 230
E++E + E +E R +K KKR++ +E +
Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 16/90 (17%)
Query: 167 TKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKG 226
TK + + E++ +K K++++EE +++ + E++E K E +E R +K KK+++
Sbjct: 46 TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105
Query: 227 QEADLEAGGEEVPEANGSAGKRSKKKKQRK 256
+E + E KKK++RK
Sbjct: 106 KEEEEE----------------KKKKRRRK 119
Score = 36.6 bits (83), Expect = 0.038
Identities = 17/61 (27%), Positives = 34/61 (55%)
Query: 164 EISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKR 223
E K K K+ E++ E ++ + E++EE +++ +R KK+ K +E +K ++R
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 224 K 224
K
Sbjct: 119 K 119
Score = 30.4 bits (67), Expect = 2.7
Identities = 18/86 (20%), Positives = 41/86 (47%), Gaps = 8/86 (9%)
Query: 148 KEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQK--------KR 199
KE++++ E + K K +++ E ++ + E +EE ++ +R
Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97
Query: 200 KREKKELKLENHQENSRNQKPKKRKK 225
K++KK + E +E + ++ K +KK
Sbjct: 98 KKKKKRRRKEEEEEKKKKRRRKTKKK 123
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/114 (30%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
K+ +++ E KK +R+++ R++K+K+E+KE + EN Q R +K K+RKK + + +
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-KRRKKKRRKERKRE 150
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
E GKR +K+K+RK E++ +RK+ E +KK+ K
Sbjct: 151 KER--------GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/148 (25%), Positives = 76/148 (51%), Gaps = 2/148 (1%)
Query: 167 TKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKG 226
T+ + + K+ E++ ++ ++ERK ER KK K+++K+ + +E R ++ K+RK+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 227 QEADLEAGGEEVP--EANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKK 284
+E + +E E + KKKK+RK+ E + R ++KRR + + K+
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 285 KKMKLPEHPEGGEPEDDEAPAKGKFNWK 312
+K + + + + +E K + N K
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRK 177
Score = 58.9 bits (141), Expect = 7e-09
Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 13/134 (9%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
K+ ++ E +K ++ER+E+ ++KRK+EKK K E Q R +K KK +K +E +
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKK--KRERKQRGRRERKKKKERKERERE---- 126
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPE 294
N +R +KK+++K E + GKR+R+ + + + ++KK +
Sbjct: 127 -------NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
Query: 295 GGEPEDDEAPAKGK 308
E E E + K
Sbjct: 180 KKERERKERRERKK 193
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/111 (27%), Positives = 63/111 (56%), Gaps = 9/111 (8%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
K E++ ++NK+ R+ +R+K+RK+++++ + + R +K KKRKK +
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER------ 168
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASE--EEARVGAGKRKRRHSEVETDSK 283
E+ E N K+ +++K+R++ E +E R ++K R ++ +TDS+
Sbjct: 169 -EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 50.1 bits (118), Expect = 3e-06
Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 184 VKKNKRERKEERQK-KRKREKKELKLENHQENSRNQKPKKRKKGQE---------ADLEA 233
+ K +R+ ER+K +R+REK++ + E ++ R +K KK++K +E + E
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 234 GGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
+E E K+ KKK++RK E + K + R ++ + K+KK +
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 6/76 (7%)
Query: 173 KVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLE 232
K + E++ + ++N++ERK+ER++K +RE+K+ + +K K+RKK ++ D +
Sbjct: 161 KKRKKEEREKKRERNRKERKKERERKERRERKK------ERKKERRKKKERKKDRKTDRQ 214
Query: 233 AGGEEVPEANGSAGKR 248
+ SA R
Sbjct: 215 TDSQVFRPLRESAFNR 230
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 57.0 bits (136), Expect = 3e-08
Identities = 32/136 (23%), Positives = 73/136 (53%), Gaps = 8/136 (5%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREK-KELKLENHQENSRN-QKPKKRKKGQEADLE 232
+D ++ ++ +RER+ ER +KR+RE+ +E + E +E R+ +K ++RK+ ++ +++
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 233 AGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEH 292
E N G+ +++ +R+ E R A +R+ R + + D +K++ + E
Sbjct: 353 R------ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
Query: 293 PEGGEPEDDEAPAKGK 308
G+ E ++ + K
Sbjct: 407 DRDGQRETEKQREREK 422
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 13/145 (8%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQ---EADLEAGGEEVPEA 241
++ +RER+ +RQ R+RE++E + ++ R ++ +K + GQ E E + E
Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
Query: 242 NGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL----PEHPEGG- 296
G+ +K+K R+ + R +RKR V + + + P P G
Sbjct: 429 GRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGI 488
Query: 297 ----EPEDDEAPAKGKFNWKGTIKA 317
PED +A A +F W KA
Sbjct: 489 RWKSSPEDPKA-ASTRFPWGRPAKA 512
Score = 45.4 bits (106), Expect = 8e-05
Identities = 25/111 (22%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQK---------PKKRKKGQEADLEAGG 235
++ ++ R+E R+++R+REK+ + H E R ++ +KR+ +E D +
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 236 EEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
E E + S+++ +R E R R+++ E +TD K+++
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/124 (20%), Positives = 60/124 (48%), Gaps = 12/124 (9%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREK-------KELKLENHQENSRNQKPKKRKKGQ 227
K+ Q + +RE++ RQK+R+RE ++ + + +E R + +K ++ Q
Sbjct: 103 KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ 162
Query: 228 -----EADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDS 282
+ E ++ E + +R ++++QR+ E+ G+ + R E ET++
Sbjct: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET 222
Query: 283 KKKK 286
++K+
Sbjct: 223 ERKR 226
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/115 (21%), Positives = 62/115 (53%), Gaps = 4/115 (3%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQ--ENSRNQKPKKRKKGQEADLEAGGEEVPEAN 242
++ +R+R++ER++KRKR+ + + N Q R Q ++R++ +E D ++ E E
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER--EER 388
Query: 243 GSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGE 297
R ++K++ + + + + + K++ R + E++ +++ + E +G E
Sbjct: 389 ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE 443
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/115 (26%), Positives = 61/115 (53%), Gaps = 6/115 (5%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKK-ELKLENHQENSRNQKPKKRKKGQEADLEAGGEE 237
E+Q E + +R ER ++R+RE++ E + E ++ R ++ ++RK +E + +A E
Sbjct: 192 ERQREKENKTEDRHSERGRERERERETETETERKRQTDR-ERDRQRKTEREREKQAERER 250
Query: 238 VPEANGSAGKRSKKKKQR---KDSASEEEARVGAGKRKRR-HSEVETDSKKKKMK 288
E K ++++ R +D +E R KR+RR + ET+ K+++ +
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/160 (18%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Query: 147 NKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKK--RKREKK 204
N+++++ E K + KD ++ ++ +R+R++ER+++ R+R+++
Sbjct: 57 NRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQ 116
Query: 205 ELKLENHQENSRNQKPKKRKKG--QEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEE 262
K N Q+ + ++ ++G ++ D + E +A +++ +++QR+ + +
Sbjct: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
Query: 263 EARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
+ R R+ R E E +K+ H E G + E
Sbjct: 177 KEREREKNRQERR-ERERQREKENKTEDRHSERGRERERE 215
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/126 (21%), Positives = 64/126 (50%), Gaps = 14/126 (11%)
Query: 175 KDAVEQQGEVKKNKRERKEER--QKKRKREK---------KELKLENHQENSRNQKPKKR 223
+DA +++ +R+R+ ER QK+R+REK ++ + EN E+ +++ ++R
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212
Query: 224 KKGQEADLEAGGEEVPEANGSAGK---RSKKKKQRKDSASEEEARVGAGKRKRRHSEVET 280
++ +E + E + + + R ++K+ ++ ASE E + + R + +
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 281 DSKKKK 286
D ++K+
Sbjct: 273 DRRQKE 278
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 179 EQQGEVKKNKR---ERKEERQKKRKREKKELKLENHQE-NSRNQKPKKRKKGQEADLEAG 234
E+Q + +K + +R+ +RQ +R R+K+ + +N QE R ++ +K K ++ E G
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 235 GEEVPEANGSAGKRSKKKKQR-KDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
E E K++ R +D + E + R SE ET+ K++
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/154 (17%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 139 EASNSEPVNKEQD-QRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQK 197
E ++E+D QR E T+ + +D ++ +R+ ++ER++
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 198 KRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKD 257
+ RE++ N Q+ +K ++ ++ +E E E E S R +++++ +
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREK--ENKTEDRHSERGRERERERETE 219
Query: 258 SASEEEARVGAGKRKRRHSEVETDSKKKKMKLPE 291
+ +E + + + ++R +E E + + ++ + E
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/163 (18%), Positives = 74/163 (45%), Gaps = 18/163 (11%)
Query: 139 EASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKK 198
E + E +E+ + + + H+E + + ++ + ++ RER +R+ +
Sbjct: 182 EKNRQERRERERQREKENKTEDRHSERGRE--RERERETETETERKRQTDRERDRQRKTE 239
Query: 199 RKREK---------------KELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANG 243
R+REK KE + E ++ R+++ K+R++ + + E E
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299
Query: 244 SAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
++ +++++R+ + E R +R+R+ E E D +K++
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQR-ETERDREKER 341
Score = 37.4 bits (85), Expect = 0.022
Identities = 27/135 (20%), Positives = 59/135 (43%), Gaps = 12/135 (8%)
Query: 164 EISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQ----- 218
+ S + P S+ G+ K+ ER ++++RE++ K + +E R +
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 219 --KPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKR--- 273
+ +KR + +E + E + + ++ +K++ R+ E R G R R
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 274 --RHSEVETDSKKKK 286
R E + D++K++
Sbjct: 145 GQRERERQRDAEKER 159
Score = 36.2 bits (82), Expect = 0.050
Identities = 32/198 (16%), Positives = 81/198 (40%), Gaps = 27/198 (13%)
Query: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKRE 202
+E + Q +R N E + + + ++ K+ +R+RK + + R+R
Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356
Query: 203 K-----------KELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKK 251
+ +E + E ++ ++ ++R++ ++ D + E E + + ++K
Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416
Query: 252 KKQR---------KDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHP------EGG 296
+++R ++ E E + G + + R ++ + ++K+ L +P G
Sbjct: 417 QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGV 476
Query: 297 EPEDDEAPAKGKFNWKGT 314
D P +G WK +
Sbjct: 477 VQSDPNRPTRG-IRWKSS 493
Score = 35.4 bits (80), Expect = 0.085
Identities = 20/116 (17%), Positives = 53/116 (45%), Gaps = 4/116 (3%)
Query: 186 KNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSA 245
+ KR+ ER ++RK E++ K + S + + +++ +E D + + +
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 246 GKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDD 301
R ++++ +D +E + +++ R E E + K+++ + E + E +
Sbjct: 283 TDRKRQRRTERDRETERKRE----RQRERERERERNRKRERERERERERERQRETE 334
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 56.6 bits (135), Expect = 4e-08
Identities = 33/128 (25%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 181 QGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPE 240
+GE ++ RE +EE++ + K E + ++E +E ++ K+ + G+E E G EE +
Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKE---EKGEEEGDQ 793
Query: 241 ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPED 300
G + + +++++ E V GK +R E E + ++++ + E E GE E+
Sbjct: 794 GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE--EEGEGEE 851
Query: 301 DEAPAKGK 308
+E KG+
Sbjct: 852 EEGEGKGE 859
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/143 (29%), Positives = 72/143 (50%), Gaps = 16/143 (11%)
Query: 173 KVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENH-----QENSRNQKPKKRKKGQ 227
K +D EQ+ ++ER++ QK+R +E +E E H +E R ++ +K +G+
Sbjct: 703 KKRDGEEQE------QKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK 756
Query: 228 EADLEAGGEEVP-EANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
E E GEEV E G+R K+++ K+ EEE G G+ + E + +
Sbjct: 757 E---EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 287 MKLPEHPEG-GEPEDDEAPAKGK 308
++ E EG GE E++E +G+
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGE 836
Score = 52.0 bits (123), Expect = 9e-07
Identities = 34/142 (23%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 175 KDAVEQQGEVKKNKRERKEERQ-KKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEA 233
+D ++GE K + E + + +K EK+E K + +E + ++ + +K + ++E
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729
Query: 234 GGEE-VPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKK-KKMKLPE 291
GGEE E G R +++++ + E E G+R++ E + + + K+ K E
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 292 HPEGGEPEDDEAPAKGKFNWKG 313
+ GE E++E +G+ +G
Sbjct: 790 EGDQGEGEEEETEGRGEEKEEG 811
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 9/130 (6%)
Query: 182 GEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEA 241
GEV++ K ER+EE ++ E++ E +E ++ + KG+E E GEE E
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEG---EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Query: 242 NGSAGKRSK---KKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEP 298
G+ + + ++ + EEE G G+ + E E + ++ + K E E GE
Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE---GEGEGEEEEGEGKGEEEGEEGEG 930
Query: 299 EDDEAPAKGK 308
E +E +G+
Sbjct: 931 EGEEEEGEGE 940
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 20/154 (12%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADL--EAGGE 236
E +GE + +RE++E +KK +R KE K E + ++ + +G+E + E G
Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGG 817
Query: 237 EVPEANGSAGKRSKK-----------------KKQRKDSASEEEARVGAGKRKRRHSEVE 279
EV E G + ++ +++ + EEE G G+ + E E
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 280 TDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKG 313
+ ++ + + E E GE E++E +G+ +G
Sbjct: 878 GEEEEGEGEGEEEGE-GEGEEEEGEGEGEEEGEG 910
Score = 45.8 bits (107), Expect = 6e-05
Identities = 36/171 (21%), Positives = 77/171 (45%), Gaps = 5/171 (2%)
Query: 148 KEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELK 207
KE++Q H E + + ++ E +G+ + E + ER+K+ KKE +
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 208 L----ENHQENSRNQKPKKRKKGQEADLEAGGE-EVPEANGSAGKRSKKKKQRKDSASEE 262
+ +E + + ++ +G+ + E GGE E E G+R +++++ + E
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 263 EARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKG 313
E G+ + E + + + ++ + E E GE E +E +G+ +G
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/140 (25%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 176 DAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGG 235
D E + E + + E KEE + E +E K E +E + ++ +G+E + E G
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE-GE 850
Query: 236 EEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEG 295
EE E G +++ ++ EEE G G+ + E E + + + E EG
Sbjct: 851 EEEGEGKG--------EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 296 -------GEPEDDEAPAKGK 308
GE E++E KG+
Sbjct: 903 EGEEEGEGEGEEEEGEGKGE 922
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 10/140 (7%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
++ E +GE K+ E + ++ K E++E + E E + ++ +G+E + E
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEA-----RVGAGKRKRRHSEVETDSKKKKMKL 289
GEE G G+ ++ ++ + EEE G G+ + E E + + +
Sbjct: 858 GEE----EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE 913
Query: 290 PEHPEG-GEPEDDEAPAKGK 308
E EG GE E +E +G+
Sbjct: 914 EEEGEGKGEEEGEEGEGEGE 933
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/138 (21%), Positives = 61/138 (44%), Gaps = 3/138 (2%)
Query: 179 EQQGEVKKNKRERKEERQK---KRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGG 235
E++GE ++ + E +EE + + + E+ E + E + ++ + +G+E G
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Query: 236 EEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEG 295
EE E G + +++ + EEE G G+ + E E + + + + E
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956
Query: 296 GEPEDDEAPAKGKFNWKG 313
GE E+ E + + +G
Sbjct: 957 GEEEEGEGEGEEEGEGEG 974
Score = 38.1 bits (87), Expect = 0.013
Identities = 28/131 (21%), Positives = 62/131 (47%), Gaps = 5/131 (3%)
Query: 179 EQQGEVKKNKRERKEERQK-KRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEE 237
E +GE ++ + + +EE ++ + + E++E + E ++ + +G+E + E GEE
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968
Query: 238 VPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGE 297
E G G+ ++++ + EEE + E E + ++++ E GE
Sbjct: 969 EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE----EGEVEGE 1024
Query: 298 PEDDEAPAKGK 308
E +E +G+
Sbjct: 1025 VEGEEGEGEGE 1035
Score = 37.4 bits (85), Expect = 0.022
Identities = 34/166 (20%), Positives = 69/166 (41%), Gaps = 13/166 (7%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEV 238
E++GE + + EE + E++E ++E E + + ++G+ E G E
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE----EEGEERE 1047
Query: 239 PEANGSAGKRSKKKKQRKD----SASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPE 294
E G +R++++++ ++ EEE G+ ++ S+++ K K K +
Sbjct: 1048 KEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKS 1107
Query: 295 GGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQY 340
+ + + K + K +LK P KK VL Y
Sbjct: 1108 VTNTQGNGKEQRSKMPVQS--KRLLKNGPSGS---KKFWNNVLPHY 1148
Score = 37.0 bits (84), Expect = 0.029
Identities = 30/136 (22%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRK-KGQEADLEA 233
++ E +GE + + E + E ++ ++E + E +E + ++ + +G+E + E
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919
Query: 234 GGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHP 293
GEE E G+ + + + +D E E G + + E E + + + E
Sbjct: 920 KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGE----GEGE 975
Query: 294 EG-GEPEDDEAPAKGK 308
EG GE E++E +G+
Sbjct: 976 EGEGEGEEEEGEGEGE 991
Score = 36.6 bits (83), Expect = 0.038
Identities = 23/110 (20%), Positives = 50/110 (45%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEV 238
E++GE + + E +EE +++ + E++ +E + + ++G+ E GEE
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE 1042
Query: 239 PEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
E G+ + ++ R++ EE G+ + + E K K+K
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
Score = 35.8 bits (81), Expect = 0.065
Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 3/105 (2%)
Query: 209 ENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGA 268
E + + + ++R+KG E D G E P G K++ +++D +E+
Sbjct: 660 EEGSSGAEHWQDEEREKG-EKDKGRGEMERP-GEGEKELAEKEEWKKRDGEEQEQKEREQ 717
Query: 269 GKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKG 313
G +K R+ E+E +++ + E EG E++E +GK +G
Sbjct: 718 GHQKERNQEMEEGGEEEHGE-GEEEEGDREEEEEKEGEGKEEGEG 761
Score = 35.8 bits (81), Expect = 0.065
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 173 KVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLE 232
+V+ VE + + + E EE ++R++E + + ++E ++ K ++ G+E +
Sbjct: 1020 EVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENER 1079
Query: 233 AGGEEVPEANGSAG--KRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLP 290
GEE + + G K K K +K S + + G GK +R V++ K L
Sbjct: 1080 QDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQ---GNGKEQRSKMPVQS-----KRLLK 1131
Query: 291 EHPEGGE 297
P G +
Sbjct: 1132 NGPSGSK 1138
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/153 (22%), Positives = 64/153 (41%), Gaps = 18/153 (11%)
Query: 168 KVPASKVKDAVEQQGEVKKNKRERKEERQKKR--KREKKELKLENHQENSRNQKPKKRKK 225
++P K + +++ + E EE K ++EK E+ ++ + + + K +
Sbjct: 585 EIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSV 644
Query: 226 GQEADLEAGGEEVPEANGSAGKR----SKKKKQRKDSASEEEARVGAGKR--------KR 273
G+ D G + GS+G +++K KD E R G G++ K+
Sbjct: 645 GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKK 704
Query: 274 RHSEVETDSKK----KKMKLPEHPEGGEPEDDE 302
R E + ++ +K + E EGGE E E
Sbjct: 705 RDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Score = 33.9 bits (76), Expect = 0.25
Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 19/138 (13%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEV 238
E +GE ++ + E +EE ++ E+ E + E E ++ + + + + E GEE
Sbjct: 978 EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE- 1036
Query: 239 PEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEP 298
+ + EE + G G+ RR+ E E + + K + E E E
Sbjct: 1037 ---------------EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE--EENER 1079
Query: 299 EDDEAPAKGKFNWKGTIK 316
+D E K KG++K
Sbjct: 1080 QDGEEYKKVS-KIKGSVK 1096
Score = 32.7 bits (73), Expect = 0.55
Identities = 35/151 (23%), Positives = 68/151 (45%), Gaps = 16/151 (10%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKP---KKRKKGQEADLEAGG 235
E +GE ++ + E +EE + + + E+ E + E E ++ K ++G+E + E G
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE-GE 933
Query: 236 EEVPEANGSAGKRSKKKKQRKDSASEEEAR-------VGAGKRKRRHSEVETDSKKKKMK 288
EE E G G+ ++++ + EEE G G+ E E + + +
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993
Query: 289 LPEHPEGGEPE---DDEAPAKGKFNWKGTIK 316
E E GE E ++E +G+ +G ++
Sbjct: 994 --EGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 56.6 bits (135), Expect = 4e-08
Identities = 53/195 (27%), Positives = 88/195 (45%), Gaps = 29/195 (14%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREKKELKLEN---HQENSRN----------QKPKKRKK 225
EQ+ E+ + K +++E ++ R++E+++ LE + E ++N K KKR
Sbjct: 846 EQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGG 905
Query: 226 GQEADLEAGGEEVPEANGSAGKR---SKKKKQRKDSASEEEARVGAGKRKRRHSEVETDS 282
G + GGE N SKKKK+RK S SE+E E E
Sbjct: 906 GGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEG------------EDEEGG 953
Query: 283 KKKKMKLPEHPEGGEPEDDEAPAKG-KFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYY 341
++KK K HP+G E DD+ G K + KA K+AP E ++ K+ ++
Sbjct: 954 ERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAI 1013
Query: 342 TVTDEHHRSEEELLV 356
+ + E++L +
Sbjct: 1014 ISSSDDSSDEDKLKI 1028
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/156 (24%), Positives = 70/156 (44%), Gaps = 15/156 (9%)
Query: 148 KEQDQRPLHPVANPHAEISTKVP-ASKVKDAVEQQGEVKKNKRERK---EERQKKRKREK 203
KEQ+++ L + + K K+ + GE + K +++ R+ K+ E
Sbjct: 858 KEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEF 917
Query: 204 KELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQR----KDSA 259
E ++ ++ K KKR+KG ++ E EE G+R KKK++R ++ +
Sbjct: 918 DEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE-------GGERKKKKRRRHPKGEEGS 970
Query: 260 SEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEG 295
++E G +KRR + E K +LP +G
Sbjct: 971 DDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKG 1006
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/186 (25%), Positives = 73/186 (39%), Gaps = 49/186 (26%)
Query: 169 VPASKVKDAVEQQGEVKKNKRERKEERQKK-RKREKKELKLENHQENSRNQKPKKRK--- 224
+P SK K + G ++ + E ER+KK R+R K + + E KPKKR+
Sbjct: 929 LPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPK 988
Query: 225 ----------------KGQ---------------EADLEAGGEEVPEANGSAGKRSKKKK 253
KG+ E L+ E P N ++ S + +
Sbjct: 989 AEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPR-NSNSNSDSDEDE 1047
Query: 254 QRKDSASEEE----------ARVGAGKRKRRH-SEVETDSKKKKMKLPEHPEGGEPEDDE 302
QRK AS E + G+ +R RR S+ ++DS + K P G E D+E
Sbjct: 1048 QRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRK--RRPSGSEQSDNE 1105
Query: 303 APAKGK 308
+ G+
Sbjct: 1106 SVQSGR 1111
Score = 29.3 bits (64), Expect = 6.1
Identities = 28/139 (20%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 173 KVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLE 232
K+K A E + + E+ Q+K+ + EN ++ +R + Q +D +
Sbjct: 1025 KLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQD 1084
Query: 233 AGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEV-ETDSKKKKMKLPE 291
+ ++ +K++ S + V +G R HS V E DS+
Sbjct: 1085 SDSDQ-----------PSRKRRPSGSEQSDNESVQSG---RSHSGVSENDSRPASPSAES 1130
Query: 292 HPEGGEPEDDEAPAKGKFN 310
E D+E +G N
Sbjct: 1131 DHESERGSDNEGSGQGSGN 1149
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 55.1 bits (131), Expect = 1e-07
Identities = 44/172 (25%), Positives = 82/172 (47%), Gaps = 14/172 (8%)
Query: 163 AEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKEL-KLENHQENSRNQKPK 221
AE++ K A+ VK ++ VKK + + E++++++++ KKE+ K E+ + +KPK
Sbjct: 618 AEVAEK-QATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPK 676
Query: 222 KRKKGQEADLEAGGEEVPEANGSAGK------------RSKKKKQRKDSASEEEARVGAG 269
K + +E E EE E K + +KK+ +K+ ++
Sbjct: 677 KEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLP 736
Query: 270 KRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQ 321
K ++ S +++KK P+ P+ E ++ A GK KG IK I K+
Sbjct: 737 KDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKE 788
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 24/204 (11%)
Query: 83 ELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASN 142
E+ + SP E+ E+ A D P KA + +K KV E ++ E +
Sbjct: 606 EVPSKEEPSPVKAEVAEK-QATDVKP--KAAKEKTVKKETKVKPEDKKEEKEKPKKEVAK 662
Query: 143 SE---PVNKEQDQRP------------LHPVANPHAEISTKVPASKVKDAV--EQQGEVK 185
E P+ KE+ + P E+ + P +VK V E++ EVK
Sbjct: 663 KEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVK 722
Query: 186 KNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSA 245
K ++E K+E +K K KK + + KPK KK + ++ P+ G
Sbjct: 723 KEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKG-- 780
Query: 246 GKRSKKKKQRKDSASEEEARVGAG 269
+ K K+ +A A VG G
Sbjct: 781 --KIKVIKKEGKAAEAVAAAVGTG 802
Score = 32.3 bits (72), Expect = 0.72
Identities = 39/167 (23%), Positives = 68/167 (40%), Gaps = 13/167 (7%)
Query: 204 KELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEE 263
K+ KL+ ++ + KP + ++ + EE PE +K K E +
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEV-------TKVNHVEKPPKVESK 583
Query: 264 ARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPA---KGKFNWKGTIKAILK 320
+V K K +E + +K++ E P + E E A K K + T+K K
Sbjct: 584 EKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETK 643
Query: 321 QAPDNEITIKKLRKKVLAQYYTVT---DEHHRSEEELLVIFNKKISK 364
P+++ K+ KK +A+ T E +EE+ K+I K
Sbjct: 644 VKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKK 690
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 54.3 bits (129), Expect = 2e-07
Identities = 47/217 (21%), Positives = 99/217 (45%), Gaps = 17/217 (7%)
Query: 81 ISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEA 140
I + + RP P E+ +Q+ + A+F+ M + K E +++ + +E+
Sbjct: 30 IQDYLNRPR--PTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLS-GNES 86
Query: 141 SNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERK-------- 192
S+ + K++ ++ ++ + + +S +D ++QG+ +K K+ R
Sbjct: 87 SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146
Query: 193 ---EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRS 249
E K+ ++KK+ K E +E KKRKK D E E++ ++
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206
Query: 250 KKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
KKK++ ++ E+A+ K+K++ + + KKKK
Sbjct: 207 KKKRRCEE---REQAKEKVKKKKKKQHKKHSKKKKKK 240
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/168 (22%), Positives = 77/168 (45%), Gaps = 17/168 (10%)
Query: 190 ERKEERQKKRKREKKELKLENHQENSRNQKPKKRKK---------GQEADLEAGGEEVPE 240
E+ E KK + +E L ++ +S+ ++ KK++K +D + + +
Sbjct: 63 EKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSED 122
Query: 241 ANGSAGKRSKKKKQR-----KDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEG 295
GKR KKKK R + S E E+ +K++ S+ ET+ +K L + +
Sbjct: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
Query: 296 GEPEDD--EAPAKGKFNWKGTIKAILK-QAPDNEITIKKLRKKVLAQY 340
P+D + + + +++ ++A K + + E +K++KK Q+
Sbjct: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQH 230
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/132 (25%), Positives = 65/132 (49%), Gaps = 7/132 (5%)
Query: 138 SEASNSEPVNKEQDQRPLHPVANPH--AEISTKVPASKVKDAVEQQGEVKKNKRERKEER 195
S +S+SE K+Q +R + ++ ST S+ K++V+++ + K + K+ R
Sbjct: 115 SSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVR 174
Query: 196 QKKRKREK-----KELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSK 250
+KR+K K L E+ E+ + + +KK + + E E+V + K+
Sbjct: 175 SLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHS 234
Query: 251 KKKQRKDSASEE 262
KKK++K +S +
Sbjct: 235 KKKKKKSGSSHK 246
Score = 39.3 bits (90), Expect = 0.006
Identities = 41/185 (22%), Positives = 74/185 (40%), Gaps = 16/185 (8%)
Query: 160 NPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQK 219
NP A + P V ++ + R EE +K+ + +K K E N+
Sbjct: 12 NPIAMARWRGPTQSVGPTIQ---DYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNEN 68
Query: 220 PKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVE 279
KK +LE E++ N S+ K+ ++KK+RK + + + S+ E
Sbjct: 69 WKK-------ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSE 121
Query: 280 TDSKK----KKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKK 335
+ KK +K K + + E+ ++ K + K K+ K + E ++ L KK
Sbjct: 122 DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKS--KDETEKEKDVRSLSKK 179
Query: 336 VLAQY 340
Y
Sbjct: 180 RKKSY 184
Score = 35.4 bits (80), Expect = 0.085
Identities = 29/121 (23%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Query: 109 RKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANP-HAEIST 167
RKK K +++ + H ES + ++ + + + KE+D R L + +
Sbjct: 131 RKKKKNRSYKSSQSSTH-ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKP 189
Query: 168 KVPASKVKDAVEQQGEVKKNKR--ERKEERQKKRKREKKELKLENHQENSRNQKPKKRKK 225
S + E+ + KK +R ER++ ++K +K++KK+ K ++ K KK+K
Sbjct: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHK--------KHSKKKKKKS 241
Query: 226 G 226
G
Sbjct: 242 G 242
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 29/266 (10%)
Query: 84 LIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNS-LKVHNESILDQVWNIFSEASN 142
L RP V L + + F P +K Q K LK ++L + + +
Sbjct: 79 LYNRPGT---VSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 135
Query: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ-KKRKR 201
VN E +R L+ + +P +P SK + K +K+ER +K KR
Sbjct: 136 G--VNSELVKRILNFLMHPKPS-GKPLPKSKKTCS-------KGSKKERNSSGMARKAKR 185
Query: 202 EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
K L + + ++K K + + D E+ EE P + ++ K+K K S
Sbjct: 186 TKCPEILSDESSSDEDEKKNKEESSDDEDKES--EEEPPKKTAKREKPKQKATSKSKKSV 243
Query: 262 EEARV-----GAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIK 316
+ A V K+ + S+ E++S+ P + +P DE K TIK
Sbjct: 244 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE-------ELKETIK 296
Query: 317 AILKQAPDNEITIKKLRKKVLAQYYT 342
+L A E+T+K++ KKV Y T
Sbjct: 297 KLLASANLEEVTMKQICKKVYENYPT 322
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 29/266 (10%)
Query: 84 LIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNS-LKVHNESILDQVWNIFSEASN 142
L RP V L + + F P +K Q K LK ++L + + +
Sbjct: 113 LYNRPGT---VSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 169
Query: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ-KKRKR 201
VN E +R L+ + +P +P SK + K +K+ER +K KR
Sbjct: 170 G--VNSELVKRILNFLMHPKPS-GKPLPKSKKTCS-------KGSKKERNSSGMARKAKR 219
Query: 202 EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
K L + + ++K K + + D E+ EE P + ++ K+K K S
Sbjct: 220 TKCPEILSDESSSDEDEKKNKEESSDDEDKES--EEEPPKKTAKREKPKQKATSKSKKSV 277
Query: 262 EEARV-----GAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIK 316
+ A V K+ + S+ E++S+ P + +P DE K TIK
Sbjct: 278 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE-------ELKETIK 330
Query: 317 AILKQAPDNEITIKKLRKKVLAQYYT 342
+L A E+T+K++ KKV Y T
Sbjct: 331 KLLASANLEEVTMKQICKKVYENYPT 356
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Query: 147 NKEQDQRPLHPVANP-------HAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKR 199
N+E+DQRP P+ + E + +V D +++ + +RER ER+++R
Sbjct: 634 NRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERER 693
Query: 200 KREK-----KELKLENHQENSR-NQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKK 253
+RE+ KE +LE + R ++ K+R + ++ D + E E K ++++
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753
Query: 254 QRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
+ ++ E E + + R E D ++++ + E + G + E
Sbjct: 754 EERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE 802
Score = 46.2 bits (108), Expect = 5e-05
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 18/157 (11%)
Query: 148 KEQDQRPLHPVANP-HAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKEL 206
KE+D++P ++ + E K S V D +Q E+ ++ R R ++ + E +E
Sbjct: 890 KEEDRKPERKESSRRYEEQELKEKVSSV-DKQREQTEILESSRMRAQDIIGHHQSEDRET 948
Query: 207 KLENHQENSRN----QKPKKRKKGQEADLEAGGEEVPEANG------------SAGKRSK 250
H EN + +KP K+KK + +E G E +G S K+ K
Sbjct: 949 SDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRK 1008
Query: 251 KKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
K K D + EE A+ KR R + T + +M
Sbjct: 1009 KSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEM 1045
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/103 (30%), Positives = 59/103 (57%), Gaps = 10/103 (9%)
Query: 179 EQQGEVKKNKRERKEERQKKRKREK-KELKLENHQENSRNQKPKKRKKGQEADLEAGGEE 237
E++ E ++ +RER+ ER+++R+RE+ +E E +E R + + + KG++ D EE
Sbjct: 748 EREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRD-DRREKREE 806
Query: 238 VPE----ANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHS 276
+ E +G ++SKK+ + + S S + + KR+R HS
Sbjct: 807 IREDRNPRDGHDERKSKKRYRNEGSPSPRQ----SPKRRREHS 845
Score = 36.2 bits (82), Expect = 0.050
Identities = 44/209 (21%), Positives = 91/209 (43%), Gaps = 25/209 (11%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
++ RER +ER+++R E K+ ++ +E + ++ ++ + ++ E ++ GS
Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRRE--KREEIREDRNPRDGHDERKSKKRYRNEGS 831
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRH--SEVETDSKKKKMK---LPEHPEGGEPE 299
R K++R+ S + G K ++ S+V + + + L E +G E
Sbjct: 832 PSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE 891
Query: 300 DDEAPAKGKFN-------WKGTIKAILKQAPDNEI-TIKKLRKKVLAQYYTVTDEH--HR 349
+D P + + + K + ++ KQ EI ++R + + ++ D R
Sbjct: 892 EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR 951
Query: 350 SEEELLVIFNK---KISKNPTFKLLKDKV 375
+ +E NK KI K P K +D V
Sbjct: 952 AHDE-----NKKKAKIQKKPIKKKKEDDV 975
Score = 33.5 bits (75), Expect = 0.32
Identities = 22/116 (18%), Positives = 55/116 (47%), Gaps = 5/116 (4%)
Query: 179 EQQGEVKKNK----RERKEERQKKRKREKKELKLENHQENSR-NQKPKKRKKGQEADLEA 233
E + E++ ++ R R E +K R + ++++H NS + + R E D
Sbjct: 550 ESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYP 609
Query: 234 GGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL 289
+ +A S+ +R ++ R+D+ ++ + + R+ E+E D ++++ ++
Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRV 665
Score = 33.1 bits (74), Expect = 0.42
Identities = 22/119 (18%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
+K R +++ R E ++H ++ + K+ +E D E E + S
Sbjct: 384 RKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSRE--EREYEQDQS 441
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEA 303
+ + + ++ +D +AR +R+ R S DS++ + + E +P D +
Sbjct: 442 SSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRS 500
Score = 32.7 bits (73), Expect = 0.55
Identities = 34/160 (21%), Positives = 69/160 (43%), Gaps = 14/160 (8%)
Query: 145 PVNKEQDQRPLHPVANPHAEISTKVPASKVKDAV----EQQGEVKKNKRERKEERQKKRK 200
P+ + P H +++P + S S +++ E+ + + ER+E+ + KR
Sbjct: 366 PLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRD 425
Query: 201 REK---KELKLENHQENSR----NQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKK 253
REK +E + E Q +SR +++P+ + ++A E+ ++ R +
Sbjct: 426 REKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDY 485
Query: 254 QR--KDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPE 291
R K+S ++R R E D+ +K+ PE
Sbjct: 486 SRDTKESRDPRDSRSTRDAHDYRDRE-GRDTHRKEDTYPE 524
Score = 32.0 bits (71), Expect = 0.94
Identities = 36/136 (26%), Positives = 60/136 (44%), Gaps = 14/136 (10%)
Query: 164 EISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKK----ELKLENHQENSRNQK 219
E+S +V SK+ + + K KR+ + K+++K L + Q NS+ +
Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQ 255
Query: 220 PKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVE 279
K KKG + +PE + + GK+ K+K + KD EE+ R G K R + E
Sbjct: 256 SK--KKGPRT--PSPPPPIPE-DIALGKKYKEKYKVKDRI-EEKTRDG----KDRGRDFE 305
Query: 280 TDSKKKKMKLPEHPEG 295
+K+ P G
Sbjct: 306 RQREKRDKPRSTSPAG 321
Score = 30.4 bits (67), Expect = 2.7
Identities = 23/130 (17%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQ----ENSRNQKPKKRKKGQEAD 230
+D +Q + +R + +R+ R+R+++ HQ E R+++ ++R+ + D
Sbjct: 611 RDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDD 670
Query: 231 -LEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL 289
+ E +R +++++ +D E+E + + + R E E + +++ +
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730
Query: 290 PEHPEGGEPE 299
+H E E
Sbjct: 731 RDHDRERERE 740
Score = 29.3 bits (64), Expect = 6.1
Identities = 21/113 (18%), Positives = 46/113 (40%), Gaps = 1/113 (0%)
Query: 188 KRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGK 247
+R+R ER + + + + + + R+ + + ++ + +E+ +
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 248 RSKKKKQRKDSASEEEARVGAGKRKR-RHSEVETDSKKKKMKLPEHPEGGEPE 299
R + R+D + E R R+R R E E D +++K + E E E
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Score = 29.3 bits (64), Expect = 6.1
Identities = 34/169 (20%), Positives = 72/169 (42%), Gaps = 12/169 (7%)
Query: 95 RELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASN-SEPVNKEQDQR 153
+EL E++S+ D K + Q + S ++ + I+ + E S+ + NK++ +
Sbjct: 908 QELKEKVSSVD-----KQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKI 962
Query: 154 PLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQE 213
P+ E + ++ E K ++K+ +KKRK+ K + + + +
Sbjct: 963 QKKPIKKKK-EDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEA 1021
Query: 214 NSRNQKPKKRKKGQEADLEAGGEEVPE-ANGSAGKRSKKKKQRKDSASE 261
++ K+K+G EE+ E NG G +K+ + S+
Sbjct: 1022 AQQS----KKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSD 1066
Score = 28.9 bits (63), Expect = 8.0
Identities = 30/144 (20%), Positives = 57/144 (39%), Gaps = 18/144 (12%)
Query: 193 EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKK 252
E+RQ + K E + K E + + R ++ + ++K D + E+ E++ +
Sbjct: 883 EDRQGRWKEEDR--KPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH 940
Query: 253 KQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWK 312
Q +D + + A D KKK K+ + P + EDD +G
Sbjct: 941 HQSEDRETSDRAH---------------DENKKKAKIQKKPIKKKKEDDVGIERGNIETT 985
Query: 313 GTIKAILK-QAPDNEITIKKLRKK 335
+ + + +I+K RKK
Sbjct: 986 SEDGQVFSPKKGQKKKSIEKKRKK 1009
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 53.1 bits (126), Expect = 4e-07
Identities = 59/225 (26%), Positives = 99/225 (44%), Gaps = 33/225 (14%)
Query: 81 ISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQ-----NWMKNSLKVHNESILDQVWN 135
I + + RP P E+ EQ+ + A+F+ NW K L+ H E +L
Sbjct: 20 IQDYLNRPR--PTWEEVKEQLEKKKKGSKALAEFEEKMNENW-KKELEKHREKLLSG--- 73
Query: 136 IFSEASNSEPVNKEQDQRPLHPVANPHAEIS-TKVPASKVKDAVEQQGEVKKNKRERK-- 192
SE+S+ + K+++++ ++ + S + +S +D ++QG+ +K K+ R
Sbjct: 74 --SESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHK 131
Query: 193 ---------EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANG 243
E K ++KK+ K +E KKRK E D E + E+
Sbjct: 132 SSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSE-DKPLSSESLSESEY 190
Query: 244 SAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
R+KKKK S+ E E K+K++H + SKKKK K
Sbjct: 191 IEEVRAKKKK----SSEEREKATEKTKKKKKHKK---HSKKKKKK 228
Score = 48.1 bits (113), Expect = 1e-05
Identities = 46/184 (25%), Positives = 71/184 (38%), Gaps = 31/184 (16%)
Query: 170 PASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQE---------NSRNQKP 220
P ++ EQ + KK + E +K + KKEL E H+E + + Q+
Sbjct: 27 PRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKEL--EKHREKLLSGSESSSKKRQRK 84
Query: 221 KKRKK---------GQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKR 271
KK KK +D + + + + GKR KKKK R +SE
Sbjct: 85 KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSM------- 137
Query: 272 KRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKK 331
SE E+DSK K + +G E E D K K + ++ I++
Sbjct: 138 ----SETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEE 193
Query: 332 LRKK 335
+R K
Sbjct: 194 VRAK 197
Score = 38.1 bits (87), Expect = 0.013
Identities = 46/202 (22%), Positives = 89/202 (44%), Gaps = 12/202 (5%)
Query: 66 KTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVH 125
K KG + +K++E K+ K RE L +S ++ +K+ + + K S +
Sbjct: 40 KKKKGSKALAEFEEKMNENWKKE--LEKHREKL--LSGSESSSKKRQRKKKEKKKSGRYS 95
Query: 126 NESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPH--AEISTKVPASKVKDAVEQQGE 183
+ S + S +S+SE +K+Q +R H +E S S KD+++++ +
Sbjct: 96 SSSSSSS--DSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKK 153
Query: 184 VKKNKRERKEERQKKRKR----EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVP 239
K + K+ + +KR E K L E+ E+ ++ + +KK + E E+
Sbjct: 154 SKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTK 213
Query: 240 EANGSAGKRSKKKKQRKDSASE 261
+ KKKK+ S+ +
Sbjct: 214 KKKKHKKHSKKKKKKAASSSPD 235
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 53.1 bits (126), Expect = 4e-07
Identities = 59/225 (26%), Positives = 99/225 (44%), Gaps = 33/225 (14%)
Query: 81 ISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQ-----NWMKNSLKVHNESILDQVWN 135
I + + RP P E+ EQ+ + A+F+ NW K L+ H E +L
Sbjct: 30 IQDYLNRPR--PTWEEVKEQLEKKKKGSKALAEFEEKMNENW-KKELEKHREKLLSG--- 83
Query: 136 IFSEASNSEPVNKEQDQRPLHPVANPHAEIS-TKVPASKVKDAVEQQGEVKKNKRERK-- 192
SE+S+ + K+++++ ++ + S + +S +D ++QG+ +K K+ R
Sbjct: 84 --SESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHK 141
Query: 193 ---------EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANG 243
E K ++KK+ K +E KKRK E D E + E+
Sbjct: 142 SSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSE-DKPLSSESLSESEY 200
Query: 244 SAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
R+KKKK S+ E E K+K++H + SKKKK K
Sbjct: 201 IEEVRAKKKK----SSEEREKATEKTKKKKKHKK---HSKKKKKK 238
Score = 48.1 bits (113), Expect = 1e-05
Identities = 46/184 (25%), Positives = 71/184 (38%), Gaps = 31/184 (16%)
Query: 170 PASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQE---------NSRNQKP 220
P ++ EQ + KK + E +K + KKEL E H+E + + Q+
Sbjct: 37 PRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKEL--EKHREKLLSGSESSSKKRQRK 94
Query: 221 KKRKK---------GQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKR 271
KK KK +D + + + + GKR KKKK R +SE
Sbjct: 95 KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSM------- 147
Query: 272 KRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKK 331
SE E+DSK K + +G E E D K K + ++ I++
Sbjct: 148 ----SETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEE 203
Query: 332 LRKK 335
+R K
Sbjct: 204 VRAK 207
Score = 38.1 bits (87), Expect = 0.013
Identities = 46/202 (22%), Positives = 89/202 (44%), Gaps = 12/202 (5%)
Query: 66 KTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVH 125
K KG + +K++E K+ K RE L +S ++ +K+ + + K S +
Sbjct: 50 KKKKGSKALAEFEEKMNENWKKE--LEKHREKL--LSGSESSSKKRQRKKKEKKKSGRYS 105
Query: 126 NESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPH--AEISTKVPASKVKDAVEQQGE 183
+ S + S +S+SE +K+Q +R H +E S S KD+++++ +
Sbjct: 106 SSSSSSS--DSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKK 163
Query: 184 VKKNKRERKEERQKKRKR----EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVP 239
K + K+ + +KR E K L E+ E+ ++ + +KK + E E+
Sbjct: 164 SKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTK 223
Query: 240 EANGSAGKRSKKKKQRKDSASE 261
+ KKKK+ S+ +
Sbjct: 224 KKKKHKKHSKKKKKKAASSSPD 245
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.8 bits (125), Expect = 5e-07
Identities = 40/176 (22%), Positives = 82/176 (46%), Gaps = 18/176 (10%)
Query: 146 VNKEQDQRPL-HPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKK 204
+ E+D+R L + + K+ K K E+Q E++K +RER+ ER+++R+R ++
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQ-EIEKERRERERERERERERRER 325
Query: 205 ELKLENHQENSRNQ---------------KPKKRKKGQEADLEAGGEEVPEANGSAGKRS 249
E + E +E + + K + R + +E D + E + N RS
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR-SRS 384
Query: 250 KKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPA 305
++K + ++ E E + + R E E + ++++ + E + + E+DE A
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/107 (20%), Positives = 59/107 (55%), Gaps = 5/107 (4%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
K RER+ ER+++R+RE++ + + ++ ++R+K ++ D E E+ E
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER--- 443
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPE 291
++ ++K + K++A +E + + +++ E E ++++++ + E
Sbjct: 444 --RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 50/244 (20%)
Query: 172 SKVKDAVEQQGEVKKNKRERKEERQKKRKREK--------------------------KE 205
S+ K ++ ++ +RER+ ER+++R+RE+ +
Sbjct: 384 SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 206 LKLEN--------HQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQ--- 254
KLE +QE +N + ++RKK +E + EA EE E K +K+ K+
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE--ERRREMAKEAKRLKEFLE 501
Query: 255 -RKDSASEEEARVGAGKRKR---RHSEVETDSKKKKMKLPEHPE-------GGEPEDDEA 303
D + + G+ +KR R E+E D + +K + E E G P+ D
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE 561
Query: 304 PAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKIS 363
+ + + + +KQ P++E ++ ++K + + +E ++ L + IS
Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPIS 621
Query: 364 KNPT 367
P+
Sbjct: 622 SAPS 625
Score = 38.9 bits (89), Expect = 0.008
Identities = 30/161 (18%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 148 KEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELK 207
+E+++R E + + ++ + K+ R+R ER + R RE+ +
Sbjct: 318 RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDR 377
Query: 208 LENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGK-----RSKKKKQRKDSASEE 262
++ + + ++R++ +E + E E E + R ++K +++D +E
Sbjct: 378 NKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDE 437
Query: 263 EARVGAGK--RKRRHSEVETDSKKKKMKLPEHPEGGEPEDD 301
E K RK R E + K ++ E + E E +
Sbjct: 438 EDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKE 478
Score = 37.4 bits (85), Expect = 0.022
Identities = 27/152 (17%), Positives = 64/152 (42%), Gaps = 10/152 (6%)
Query: 144 EPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREK 203
E KE++++ + + + ++ ++ ++ ++ER+ ER++ R R++
Sbjct: 294 EKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDR 353
Query: 204 -KELKLENHQENSRNQ---------KPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKK 253
KE + +E R++ K + R + + D E E E + ++++
Sbjct: 354 TKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERER 413
Query: 254 QRKDSASEEEARVGAGKRKRRHSEVETDSKKK 285
+R+ E R KR R E + ++K
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRK 445
Score = 35.4 bits (80), Expect = 0.085
Identities = 39/199 (19%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 158 VANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSR- 216
+A H + ++ + + +Q ++K+ +EE +K+ K EK+E +E +E +
Sbjct: 551 LAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Query: 217 ----------NQKPKKRKKGQEADLEAGGEE------VPEANGSAGKRSKKKKQR----- 255
+ P A G+E +P N ++ ++ + +
Sbjct: 611 PCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSL 670
Query: 256 KDSASEEEARVGAGKRKR--------RHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKG 307
K AS + + KRK+ + + ++D +K KL G EDD+ KG
Sbjct: 671 KLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYG---EDDKNATKG 727
Query: 308 KFNW---KGTIKAILKQAP 323
N + IK+++++ P
Sbjct: 728 TVNTEEKRKHIKSLIEKIP 746
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 52.8 bits (125), Expect = 5e-07
Identities = 40/224 (17%), Positives = 100/224 (44%), Gaps = 24/224 (10%)
Query: 65 GKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKV 124
GK H G K +A ++++ E +++ P E L++ + R+K + + + K
Sbjct: 214 GKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQ-EREEREKEREREREERERKR 272
Query: 125 HNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEV 184
E E + +++++R + H+ ++ S+ +D
Sbjct: 273 RRE-----------EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRD-------- 313
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
+KR R ER++ R R+++ + + E + + R++ + D ++ +
Sbjct: 314 --HKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDRE 371
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
++SK+K++R + ++++ V +G R+++ + T+SK+ K
Sbjct: 372 QDRKSKEKEKR--GSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 2/123 (1%)
Query: 172 SKVKDAVEQQGEVKKNKRER--KEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEA 229
+K+K VE+ E + + E ++ER KK K+E++E + E +E ++ ++R++ +
Sbjct: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEERE 280
Query: 230 DLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL 289
A E + + S + S + R+ S S + R + +R+R S S+
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 290 PEH 292
+H
Sbjct: 341 RKH 343
Score = 28.9 bits (63), Expect = 8.0
Identities = 13/79 (16%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKR-KKGQEADLEAGGEEVPEANG 243
+ R+R+ + + RK K K + +++ ++++ +KR +++ +++G E +
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 244 SAGKRSKKKKQRKDSASEE 262
+ + K + SE+
Sbjct: 404 NTESKESDTKNEVNGTSED 422
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 52.8 bits (125), Expect = 5e-07
Identities = 40/224 (17%), Positives = 100/224 (44%), Gaps = 24/224 (10%)
Query: 65 GKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKV 124
GK H G K +A ++++ E +++ P E L++ + R+K + + + K
Sbjct: 214 GKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQ-EREEREKEREREREERERKR 272
Query: 125 HNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEV 184
E E + +++++R + H+ ++ S+ +D
Sbjct: 273 RRE-----------EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRD-------- 313
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
+KR R ER++ R R+++ + + E + + R++ + D ++ +
Sbjct: 314 --HKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDRE 371
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMK 288
++SK+K++R + ++++ V +G R+++ + T+SK+ K
Sbjct: 372 QDRKSKEKEKR--GSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 2/123 (1%)
Query: 172 SKVKDAVEQQGEVKKNKRER--KEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEA 229
+K+K VE+ E + + E ++ER KK K+E++E + E +E ++ ++R++ +
Sbjct: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEERE 280
Query: 230 DLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL 289
A E + + S + S + R+ S S + R + +R+R S S+
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 290 PEH 292
+H
Sbjct: 341 RKH 343
Score = 28.9 bits (63), Expect = 8.0
Identities = 13/79 (16%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKR-KKGQEADLEAGGEEVPEANG 243
+ R+R+ + + RK K K + +++ ++++ +KR +++ +++G E +
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 244 SAGKRSKKKKQRKDSASEE 262
+ + K + SE+
Sbjct: 404 NTESKESDTKNEVNGTSED 422
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 52.4 bits (124), Expect = 7e-07
Identities = 64/266 (24%), Positives = 107/266 (40%), Gaps = 34/266 (12%)
Query: 139 EASNSEPVNKEQ-DQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQK 197
E PV K +++ PV+ E K P K E + + + K E+KEE +K
Sbjct: 649 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPK-SPVEEAKSKAEVGKGEQKEEEEK 707
Query: 198 KRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQR-- 255
+ K KE K+E +E ++ P+K+K EA E V K+ K+
Sbjct: 708 EVKEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGK 766
Query: 256 --KDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAK--GKFNW 311
+ +E+A G + + S+K+ + + EG E + E K G+
Sbjct: 767 PLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 826
Query: 312 KGTIKAILKQAPDNE-----------ITIKKLRK----------KVLAQYYTVT---DEH 347
KG + L +P +E + K + K K + + TVT +EH
Sbjct: 827 KGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEH 886
Query: 348 HRSEEELLVIFNKKISKNPTFKLLKD 373
+ EE LV KK+ K + ++K+
Sbjct: 887 EETFEEKLV-STKKVEKVTSHAIVKE 911
Score = 40.4 bits (93), Expect = 0.003
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 31/230 (13%)
Query: 81 ISELIKRPNV-SPKVR---ELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNI 136
IS I++P V +PK++ + +E+I V +K++ M+ +L E + +
Sbjct: 432 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSE----MEEALTAITEELAVSMKEE 487
Query: 137 FSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ 196
EA+ +E+++ P E + A+K EVK+ + E++EE
Sbjct: 488 KKEAA------EEKEEEP---------EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG 532
Query: 197 KKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRK 256
++ + E+ E + E ++K +K + E E E + K KK +++
Sbjct: 533 QEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS 592
Query: 257 DSASEEEARVGAGKRKRRH--------SEVETDSKKKKMKLPEHPEGGEP 298
+ + +E V K ++ S VE K K P +G P
Sbjct: 593 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/124 (22%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
Query: 184 VKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANG 243
+K+ K+E EE++++ + E++E+ + + + K+ ++G++ + E EE E G
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE-EEGEKEEEEGQEEEEEEDEG 542
Query: 244 SAGKRSKKKKQRKDSASE-EEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
+ ++++ K+ +SE EE G+ + E ++K++K + E E+
Sbjct: 543 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 602
Query: 303 APAK 306
A AK
Sbjct: 603 ADAK 606
Score = 33.9 bits (76), Expect = 0.25
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 197 KKRKREKKELKLENH--QENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQ 254
+K K E +LK+++ +E K + K E L A EE+ + K + ++K+
Sbjct: 437 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 496
Query: 255 RKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
+ A EEE K EV+ + +K E EG E E++E
Sbjct: 497 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEK-----EEEEGQEEEEEE 539
Score = 33.9 bits (76), Expect = 0.25
Identities = 31/133 (23%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
K+A E+ K+ + E +EE +K K E +E ++ + +++ +E D E
Sbjct: 489 KEAAEE----KEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED-EGA 543
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEARV-GAGKRKRRHSEVETDSKK--KKMKLPE 291
+ E GS + S +K++ + E EA G + +VE S++ K +L
Sbjct: 544 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 603
Query: 292 HPEGGEPEDDEAP 304
+ +PE ++P
Sbjct: 604 DAKVEKPEKAKSP 616
Score = 30.0 bits (66), Expect = 3.6
Identities = 43/189 (22%), Positives = 78/189 (41%), Gaps = 30/189 (15%)
Query: 158 VANPHAEISTKVPASKVKDAVEQQGE--VKKNKRERK----------EERQKK------- 198
VA+ E K + K VE++G+ V K+ E K EE+ K
Sbjct: 602 VADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPV 661
Query: 199 RKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG-----GEEVPEANGSAGKRSKKKK 253
++ K + +E +++ PK + ++ E G EE E + + +KK
Sbjct: 662 EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 721
Query: 254 QRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL-PEHPEGGEP-----EDDEAPAKG 307
+ K E+ + + ++ +EV T +K K+ L E E G+P E ++A +G
Sbjct: 722 EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEG 781
Query: 308 KFNWKGTIK 316
+G+ K
Sbjct: 782 GSEEEGSDK 790
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 52.4 bits (124), Expect = 7e-07
Identities = 64/266 (24%), Positives = 107/266 (40%), Gaps = 34/266 (12%)
Query: 139 EASNSEPVNKEQ-DQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQK 197
E PV K +++ PV+ E K P K E + + + K E+KEE +K
Sbjct: 273 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPK-SPVEEAKSKAEVGKGEQKEEEEK 331
Query: 198 KRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQR-- 255
+ K KE K+E +E ++ P+K+K EA E V K+ K+
Sbjct: 332 EVKEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGK 390
Query: 256 --KDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAK--GKFNW 311
+ +E+A G + + S+K+ + + EG E + E K G+
Sbjct: 391 PLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 450
Query: 312 KGTIKAILKQAPDNE-----------ITIKKLRK----------KVLAQYYTVT---DEH 347
KG + L +P +E + K + K K + + TVT +EH
Sbjct: 451 KGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEH 510
Query: 348 HRSEEELLVIFNKKISKNPTFKLLKD 373
+ EE LV KK+ K + ++K+
Sbjct: 511 EETFEEKLV-STKKVEKVTSHAIVKE 535
Score = 40.4 bits (93), Expect = 0.003
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 31/230 (13%)
Query: 81 ISELIKRPNV-SPKVR---ELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNI 136
IS I++P V +PK++ + +E+I V +K++ M+ +L E + +
Sbjct: 56 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSE----MEEALTAITEELAVSMKEE 111
Query: 137 FSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ 196
EA+ +E+++ P E + A+K EVK+ + E++EE
Sbjct: 112 KKEAA------EEKEEEP---------EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG 156
Query: 197 KKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRK 256
++ + E+ E + E ++K +K + E E E + K KK +++
Sbjct: 157 QEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS 216
Query: 257 DSASEEEARVGAGKRKRRH--------SEVETDSKKKKMKLPEHPEGGEP 298
+ + +E V K ++ S VE K K P +G P
Sbjct: 217 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/124 (22%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
Query: 184 VKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANG 243
+K+ K+E EE++++ + E++E+ + + + K+ ++G++ + E EE E G
Sbjct: 108 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE-EEGEKEEEEGQEEEEEEDEG 166
Query: 244 SAGKRSKKKKQRKDSASE-EEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
+ ++++ K+ +SE EE G+ + E ++K++K + E E+
Sbjct: 167 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 226
Query: 303 APAK 306
A AK
Sbjct: 227 ADAK 230
Score = 33.9 bits (76), Expect = 0.25
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 197 KKRKREKKELKLENH--QENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQ 254
+K K E +LK+++ +E K + K E L A EE+ + K + ++K+
Sbjct: 61 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 120
Query: 255 RKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
+ A EEE K EV+ + +K E EG E E++E
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEK-----EEEEGQEEEEEE 163
Score = 33.9 bits (76), Expect = 0.25
Identities = 31/133 (23%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
K+A E+ K+ + E +EE +K K E +E ++ + +++ +E D E
Sbjct: 113 KEAAEE----KEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED-EGA 167
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEARV-GAGKRKRRHSEVETDSKK--KKMKLPE 291
+ E GS + S +K++ + E EA G + +VE S++ K +L
Sbjct: 168 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Query: 292 HPEGGEPEDDEAP 304
+ +PE ++P
Sbjct: 228 DAKVEKPEKAKSP 240
Score = 30.0 bits (66), Expect = 3.6
Identities = 43/189 (22%), Positives = 78/189 (41%), Gaps = 30/189 (15%)
Query: 158 VANPHAEISTKVPASKVKDAVEQQGE--VKKNKRERK----------EERQKK------- 198
VA+ E K + K VE++G+ V K+ E K EE+ K
Sbjct: 226 VADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPV 285
Query: 199 RKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG-----GEEVPEANGSAGKRSKKKK 253
++ K + +E +++ PK + ++ E G EE E + + +KK
Sbjct: 286 EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 345
Query: 254 QRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKL-PEHPEGGEP-----EDDEAPAKG 307
+ K E+ + + ++ +EV T +K K+ L E E G+P E ++A +G
Sbjct: 346 EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEG 405
Query: 308 KFNWKGTIK 316
+G+ K
Sbjct: 406 GSEEEGSDK 414
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 52.4 bits (124), Expect = 7e-07
Identities = 48/211 (22%), Positives = 97/211 (45%), Gaps = 18/211 (8%)
Query: 139 EASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNK------RERK 192
E S+ E + +E +R A AE ++ A + K +++ ++ + RER+
Sbjct: 250 EISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERR 309
Query: 193 EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKK 252
E +++R RE+++ E Q +K ++ + + E E + KR+ ++
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 253 KQRKDSASEEEARVGAGKR-----KRRHSEVETDSKKKKM------KLPEHPEGGEPEDD 301
+QR + EE+A+V KR +++H+ ET K +K+ K + E +
Sbjct: 370 RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ 429
Query: 302 EAPAKGKFNWKGT-IKAILKQAPDNEITIKK 331
A K + KGT ++A ++ +++ T KK
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKK 460
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/192 (21%), Positives = 85/192 (44%), Gaps = 8/192 (4%)
Query: 164 EISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKR 223
+ S +P+ ++++ + +K E+ E RQ++ + E+ E +++Q+N + +
Sbjct: 127 DASLSLPSRRMQNDTAENETTEKE--EKSESRQERYEIEETETVTKSYQKNDWRDAEENK 184
Query: 224 KKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSK 283
K+ +E + E EE P+ + + + K + S+EE V + K + SE +
Sbjct: 185 KEDKEKEEEE--EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEE 242
Query: 284 KKKMKLPE--HPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYY 341
+++ E H E E ED E + + + +K D +I + R ++ A+
Sbjct: 243 EREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE--RARIEAEEK 300
Query: 342 TVTDEHHRSEEE 353
E R E E
Sbjct: 301 AAAQERERREAE 312
Score = 40.8 bits (94), Expect = 0.002
Identities = 55/250 (22%), Positives = 104/250 (41%), Gaps = 47/250 (18%)
Query: 55 DQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAF---------- 104
+QK GK K + D Q A ++K E K V K +L E F
Sbjct: 410 EQKIEGKWVNEKKAQEDKLQTAVLKKQGEE-KGTKVQAKREKLQEDKPTFKKEEIKDEKI 468
Query: 105 --DNVPRKKAK-FQNWMKNSLKVHNES------ILDQVWNIFSEASNSEPVNKEQDQRPL 155
D P+++ K F + K +V +++ L N FS V+ ++
Sbjct: 469 KKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE----- 523
Query: 156 HPVANPHAEISTKVPASK-VKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQEN 214
AE + +V A K +++ ++GE + + E+ +++Q++ E +ELK + +
Sbjct: 524 -------AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERR 576
Query: 215 SRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRR 274
++ ++R+K +EAD + R +++K+R E A KR++
Sbjct: 577 KVLEEEEQRRKQEEADRKL--------------REEEEKRRLKEEIERRRAEAAEKRQKM 622
Query: 275 HSEVETDSKK 284
+ +D KK
Sbjct: 623 PEDGLSDDKK 632
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 173 KVKDAVEQQGEVKKNKRERK---EERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEA 229
K ++A + E+KK + ER+ EE +++RK+E+ + KL +E R ++ +R++ + A
Sbjct: 557 KQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA 616
Query: 230 DLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEAR 265
+ +++PE S K+ K K S+ + E R
Sbjct: 617 EKR---QKMPEDGLSDDKKPFKCFTPKGSSLKIEER 649
Score = 39.3 bits (90), Expect = 0.006
Identities = 40/192 (20%), Positives = 85/192 (44%), Gaps = 8/192 (4%)
Query: 138 SEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVK--KNKRERKEER 195
+E + E KE+++ P E +V + +++ V KN + EE
Sbjct: 180 AEENKKEDKEKEEEEEE-KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 196 QKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS---AGKRSKKK 252
+++ +RE+ ++ +H++ ++ K+R + + A LEA E +A A +R++ +
Sbjct: 239 KQEEEREQGSDEISHHEK--MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIE 296
Query: 253 KQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWK 312
+ K +A E E R + + R E +++++K E E + + K +
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356
Query: 313 GTIKAILKQAPD 324
IK K+A +
Sbjct: 357 QRIKEEEKRAAE 368
Score = 39.3 bits (90), Expect = 0.006
Identities = 48/188 (25%), Positives = 77/188 (40%), Gaps = 34/188 (18%)
Query: 138 SEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRE------- 190
+ A E E+ +R HA TK+ KV+ +E + +K +E
Sbjct: 373 ARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAV 432
Query: 191 -RKEERQKKRKREKKELKLEN-----HQENSRNQKPKKRKKGQE-----ADLEAGGEEVP 239
+K+ +K K + K KL+ +E +++K KK K+ +E D + G EV
Sbjct: 433 LKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 492
Query: 240 EANGSAGKRSKKKKQR-------KDSASEEEA----RVGAGKR----KRRHSEVETDS-K 283
NG K + + S +EA +V AGKR +RR E E++ +
Sbjct: 493 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 552
Query: 284 KKKMKLPE 291
K K K E
Sbjct: 553 KLKQKQQE 560
Score = 30.4 bits (67), Expect = 2.7
Identities = 37/176 (21%), Positives = 72/176 (40%), Gaps = 28/176 (15%)
Query: 141 SNSEPVNKEQDQRPLHPVANP-HAEISTKVPASKVKDA-----VEQQGEVKKNKR-ERKE 193
+ E + ++Q++ L V + VP + K VE E +R R+E
Sbjct: 45 ARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARRE 104
Query: 194 ERQKKRKRE--KKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKK 251
ER++KR +E +++ + + ++ P +R + A+ N + K K
Sbjct: 105 ERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE-----------NETTEKEEKS 153
Query: 252 KKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKG 307
+ +++ EE V +K + E + K+ K K E E++E P +G
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK--------EEEEEEKPKRG 201
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 52.4 bits (124), Expect = 7e-07
Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 12/132 (9%)
Query: 171 ASKVKDAVEQQGEVKKN---KRERKEERQKKRKREKKELKLENHQENSR-NQKPKKRKKG 226
A K+K E+ G ++K + R+ ER+K+R+REK+ LE QE R ++ K R++
Sbjct: 482 AEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE---LEKEQEQEREKEREKDRERQ 538
Query: 227 QEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
QE + E E+ + + K++KQ K+ E + +K + E E + +K++
Sbjct: 539 QEKEKELEKEQEKQR-----EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
Query: 287 MKLPEHPEGGEP 298
KL E E EP
Sbjct: 594 EKLEEKIEPREP 605
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/192 (21%), Positives = 90/192 (46%), Gaps = 15/192 (7%)
Query: 172 SKVKDAVEQQGEVKKNKRERKEERQK-----KRKREKKELKLENHQENSRNQKPKKRKKG 226
S++ AVE+ + ++ + R EE++K K KR ++L + Q + + ++R+K
Sbjct: 453 SEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKE 512
Query: 227 QEADLEAGGEEVPEANGSAGK-RSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKK 285
+E + E E+ E K R +++++ K+ E+E + K +++ E E + +K+
Sbjct: 513 REREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKE 572
Query: 286 K----MKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYY 341
K K+ E + E E + + K + + + ++E + K + V +
Sbjct: 573 KEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTR-- 630
Query: 342 TVTDEHHRSEEE 353
+ +RSE+E
Sbjct: 631 ---QDSNRSEKE 639
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 165 ISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRK--------REKKELKLENHQENSR 216
I K P+ + E++ E ++ K KE+ Q++ K +++KE +LE QE R
Sbjct: 494 ILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQR 553
Query: 217 NQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHS 276
+ K+RK+ +E +LE E+ E K K+Q K+ E+E K + R
Sbjct: 554 EME-KERKQEKEKELERQKEKEKEL-------QKMKEQEKECELEKEREKLEEKIEPREP 605
Query: 277 EVETDSKKKK 286
+E +K++
Sbjct: 606 NLEPMVEKQE 615
Score = 37.7 bits (86), Expect = 0.017
Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 46/255 (18%)
Query: 126 NESILDQVWNIFSEASNSEPVN--KEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGE 183
N++ DQ + AS S N +E+D++ +A+++ + ++ + + E
Sbjct: 1485 NQNSSDQANEEWETASESSDFNERRERDEKK-------NADLNAQTVVKVGENVLPPKRE 1537
Query: 184 VKKNK--RERKEERQKKRKREKKELKLENHQ--ENSRNQKP--KKRKKGQEADLEAGGEE 237
+ K +R +RQ +R N N R P K K+G D AG
Sbjct: 1538 IAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTG 1597
Query: 238 VPEANGSAGKRSKK------KKQRKDSASEEEARVGAGKRKRRH-----SEVETDSKKKK 286
V NGS+ + +K KDS ++ G +K + S+ + ++
Sbjct: 1598 VDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASV 1657
Query: 287 MKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDE 346
+ + +HPE ED ++ L E+ KK +K++ +E
Sbjct: 1658 VIIDDHPEVTVIEDPQSN--------------LNDDGFTEVVSKKQQKRLQ------DEE 1697
Query: 347 HHRSEEELLVIFNKK 361
+ EE+++ ++NKK
Sbjct: 1698 RRKKEEQVIQVWNKK 1712
Score = 36.2 bits (82), Expect = 0.050
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 9/141 (6%)
Query: 175 KDAVEQQGEVKKNKRERKEE------RQKKRKREKKELKLENHQENSRNQKPKK-RKKGQ 227
K V + E+ K +R ++ E R +KR RE++E ++E ++ + +K K+ +K
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKR-REEEERRMEEQRKAACAEKLKRLDEKLG 493
Query: 228 EADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
+ + EE+ E +R ++K+ K+ E E + +++ E E + +++K
Sbjct: 494 ILEKQPSPEEIREREREK-EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQ 552
Query: 288 KLPEHPEGGEPEDDEAPAKGK 308
+ E E E + K K
Sbjct: 553 REMEKERKQEKEKELERQKEK 573
Score = 35.8 bits (81), Expect = 0.065
Identities = 43/200 (21%), Positives = 83/200 (41%), Gaps = 21/200 (10%)
Query: 130 LDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKR 189
LD+ I + + E + + + ++ E + + KD QQ + ++
Sbjct: 488 LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQ----EKEK 543
Query: 190 ERKEERQKKRKREK-----KELKLENHQENSRN-QKPKKRKKGQEADLEAGGEEVPEANG 243
E ++E++K+R+ EK KE +LE +E + QK K+++K E +LE E++ E
Sbjct: 544 ELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEK--ECELEKEREKLEE--- 598
Query: 244 SAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEA 303
K ++ + ++E+ K + + ++ +K P E EPE
Sbjct: 599 ---KIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHE-TEPESGSQ 654
Query: 304 PAKGKFNWKGTIKAILKQAP 323
P + G K K P
Sbjct: 655 PRPAVLS--GYFKQFQKSLP 672
Score = 31.2 bits (69), Expect = 1.6
Identities = 40/174 (22%), Positives = 66/174 (37%), Gaps = 31/174 (17%)
Query: 138 SEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQK 197
SE+S+ E V K + QR +E T S++ ++ + + K K ++EER +
Sbjct: 1246 SESSDFEVVPKRRRQRG--------SETDTD---SEIHESASDKDSLSKGKLPKREERPE 1294
Query: 198 KRKREK--KELKLENHQ--ENSRNQKPKKRKKGQ-EADLEAGGEEVPEANGSAGKRSKKK 252
+K K K +NH +N +KP R + + GE G +R +
Sbjct: 1295 NKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRD 1354
Query: 253 KQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAK 306
G R R S + + + P E +PED E P +
Sbjct: 1355 P---------------GGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRR 1393
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 52.0 bits (123), Expect = 9e-07
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 2/121 (1%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQK--PKKRKKGQEADLE 232
K+ ++ + ++ RER +E++ + + E+K+ K + R+ K KK KK +
Sbjct: 372 KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431
Query: 233 AGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEH 292
+ +AGKRS+ + + K S + E++ + KR R S+ TDS +K K
Sbjct: 432 ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHS 491
Query: 293 P 293
P
Sbjct: 492 P 492
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 14/142 (9%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
KD + + + +K+E+K R + R+R+ + + SRN + R + +E +
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRS------RSRSRNAGKRSRSRSKEKSSKHK 460
Query: 235 GEEVPEAN-----GSAGKRS--KKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
E ++N GS G+ +K K+R+ S S+E++R + ++R H +DSK +
Sbjct: 461 NESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSD 520
Query: 288 KLP-EHPEGGEPEDDEAPAKGK 308
K + E E E K K
Sbjct: 521 KHDRRRSQSIEQESQEKQHKNK 542
Score = 47.0 bits (110), Expect = 3e-05
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 9/102 (8%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
+ +R R R + RK ++++ E +EN R R++ ++ D E G E E S
Sbjct: 331 RSRERHRSRSRSRDRKGDRRDRDREREKENERG-----RRRDRDYDKERGNEREKERERS 385
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
+RSK+++ R + EE + K RRH + + DSKK+K
Sbjct: 386 R-ERSKEQRSRGEV---EEKKHKEDKDDRRHRDDKRDSKKEK 423
Score = 38.5 bits (88), Expect = 0.010
Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
Query: 190 ERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRS 249
+R+ ER+K+R+R ++E K +K ++R + + LE E + S +
Sbjct: 292 DRELEREKERQRLEREAK--------EREKERRRSRSIDRGLERRRSRSRERHRSRSRSR 343
Query: 250 KKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKK 286
+K R+D E E G+R+ R + E ++++K
Sbjct: 344 DRKGDRRDRDREREKENERGRRRDRDYDKERGNEREK 380
Score = 37.4 bits (85), Expect = 0.022
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 197 KKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRK 256
++ +REK+ +LE +E +K ++R + + LE E + S + +K R+
Sbjct: 293 RELEREKERQRLE--REAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRR 350
Query: 257 DSASEEEARVGAGKR------KRRHSEVETDSKKKKMKLPEHPEGGEPED 300
D E E G+R K R +E E + ++ + + E GE E+
Sbjct: 351 DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEE 400
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 51.6 bits (122), Expect = 1e-06
Identities = 49/222 (22%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 79 QKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFS 138
+KI E KR R+ E+I + + R+K K M K+ + ++VW
Sbjct: 450 EKIREEEKRQEQEEMWRQE-EKIREQEEIWRQKEK----MHEQEKIRKQE--EKVWRQEE 502
Query: 139 EASNSEPVNKEQDQRPLHPVAN-PHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQK 197
+ + E +EQ+++ E + K+++ E E ++ E++E+ Q+
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 198 KRKREKKELKLENHQENSRNQKPKKRKKG-----QEADLEAGGEEVPEANGSAGKRSKKK 252
+ K ++E K+ +E R QK K R++ QE + E + E ++ +K
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 253 KQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPE 294
++++ E+E ++ + K EV +++KM+ EH E
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ--EHQE 662
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/230 (19%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Query: 64 EGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLK 123
E K + + K Q W +KI E K+RE E+I + R++ + W K
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQ------EEKIREQEEKIREQEEKMRRQEEMM-WEKEEKM 351
Query: 124 VHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGE 183
E ++ W + E + E++++ H + + K ++ + + +
Sbjct: 352 RRQEEMM---WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 184 VKKNKRERKEERQKKRKRE------KKELKLENHQENSRNQKPKKRKKGQEADLEAGGEE 237
K+ ++E K RQ+++ RE ++E K+ +E Q+ + ++ ++ E +E
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 238 VPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
R K+K ++ ++E +V + K E + +++KM
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Score = 39.7 bits (91), Expect = 0.005
Identities = 33/199 (16%), Positives = 88/199 (44%), Gaps = 12/199 (6%)
Query: 93 KVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQ 152
K+REL E++ + + ++ K Q K + + ++W + E +EQ++
Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
Query: 153 RPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQ 212
+ H + K+++ E ++ + E + +K R++E+ + E
Sbjct: 438 KMWRQEEKIHEQ-------EKIREE-----EKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Query: 213 ENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRK 272
E + +K +++ QE + E++ E ++ +K +++++ E+E ++ +
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 273 RRHSEVETDSKKKKMKLPE 291
+ E + +++KM+ E
Sbjct: 546 MQEQEEKMGEQEEKMQEQE 564
Score = 37.7 bits (86), Expect = 0.017
Identities = 42/208 (20%), Positives = 91/208 (43%), Gaps = 5/208 (2%)
Query: 83 ELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASN 142
+LI R + S K LEQ A V +K K +++ K + L+ N ++
Sbjct: 162 DLISRLHDSWKFAGELEQ--ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEEL 219
Query: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDA--VEQQGEVKKNKRERKEERQKKRK 200
E K Q++ L +++ K K++ A + Q +++ +E Q
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 201 REKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSAS 260
+ + +++ EN N NQ+ +++ QE ++ E++ E ++ +K +++++
Sbjct: 280 KLQAQVE-ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 338
Query: 261 EEEARVGAGKRKRRHSEVETDSKKKKMK 288
+E + + K R E K++KM+
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Score = 34.3 bits (77), Expect = 0.19
Identities = 32/170 (18%), Positives = 75/170 (44%), Gaps = 17/170 (10%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGS 244
K+ K R EE +++ + +EL+ + H++ ++ +KR QE + E+ E
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKR---QEEEKIREQEKRQEQEAK 417
Query: 245 AGKRSKKKKQRKDSASEEEARVGAGKRKRRHSE-VETDSKKKKMKLPEHPEGGEPEDDEA 303
++ +K +++++ E+E ++ + K E + + K+++ + E E +E
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Query: 304 PAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEE 353
W+ K+ + I+K +KV Q + D+ + E+
Sbjct: 478 -------WR------QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ 514
Score = 32.7 bits (73), Expect = 0.55
Identities = 27/171 (15%), Positives = 75/171 (43%), Gaps = 5/171 (2%)
Query: 183 EVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEAN 242
E+ K E+ E ++K ++K + E ++ + +++++ QEA + E++ E
Sbjct: 370 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429
Query: 243 GSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDE 302
++ KK ++++ E+E KR+ + + K ++ + + E ++
Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK 489
Query: 303 APAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEE 353
+ + W+ ++ D E I++ +K+ Q + ++ + E+
Sbjct: 490 IRKQEEKVWRQE-----EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 51.6 bits (122), Expect = 1e-06
Identities = 70/325 (21%), Positives = 140/325 (43%), Gaps = 50/325 (15%)
Query: 84 LIKRPNVSPKVRELLEQISAFDN--------VPRKKAKFQNWMK--NSLKVHNESILDQV 133
L P RE+ IS+ N V R K K + N ++ + S L Q
Sbjct: 463 LAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQS 522
Query: 134 WNIFSEASNSEPVNKEQDQRPLHP---VANPHAEISTKVPASKVKDAVEQQGEVKKNKRE 190
+ +E EP + D L + E + ++ + + ++ E++ K+ +RE
Sbjct: 523 QSS-TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERE 581
Query: 191 RKEERQKKRKREKKELKLENHQENSRNQKPK-KRKKGQEADLEAGGE---EVPEANGSAG 246
R+ E++K+R+REK++LK + +S K K K G++ + E + E+ +A S
Sbjct: 582 REREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQK 641
Query: 247 K--------RSKKKKQRKD---SASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEG 295
+ RS K+QR A+E++++ ++R ++E KK+ K+
Sbjct: 642 EMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKM------ 695
Query: 296 GEPEDDEAPAKGKFNWKGTIKAILKQAP--DNEITIKKLRKKVLAQYYTVTDE--HHRSE 351
D++A K I+A+ +Q ++ + K ++ L VT + E
Sbjct: 696 ---ADEDALRK--------IRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQE 744
Query: 352 EELLVIFNKKISKNPTFKLLKDKVK 376
+ + ++ + + FKL+ +++K
Sbjct: 745 QNIRLMQQLREKDDANFKLMSERIK 769
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/236 (25%), Positives = 105/236 (44%), Gaps = 26/236 (11%)
Query: 85 IKRPNVSPKVRELLEQISAFDNVPRK-KAKFQNWMKNSLKVHNESILDQVWNIFSEASNS 143
+K P +E E S D P K K+ + +K+ K + D ++A
Sbjct: 761 VKSPEAKTPAKE--EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED------AKAPEK 812
Query: 144 EPVNKEQDQRPLHPVANPHAEISTKVPASKVKD----AVEQQGEVKKNKRER--KEERQK 197
E KE+ + P+ P E+ K P K ++ A + E K +K+E K+E K
Sbjct: 813 EIPKKEEVKSPVKEEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 198 KRKREKKELKLENHQEN---SRNQKPKKRKKGQEADLEAGGE-EVPEANGSAGKRSKKKK 253
+ EKKE +E +E+ ++ ++ + +KK + EA + EV E K KK
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 254 QRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEH---PEGGEPEDDEAPAK 306
+ D+ ++E ++ K+ + + D+K++K K PE E EDD+ +K
Sbjct: 932 EPDDAKAKEPSKPA---EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK 984
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/228 (21%), Positives = 103/228 (45%), Gaps = 23/228 (10%)
Query: 168 KVPASKVKDAVEQQGEVKKNKRERKE----ERQKKRKREKKELKLENHQENSRNQKPKKR 223
K+P+ V+ + ++K ++ KE E Q + + +E+ E +E ++ ++ K+
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE-AKEEEGKEE 486
Query: 224 KKGQEADLEAGGEEV---PEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVET 280
+ G+E + E G EE P ++ ++ K ++++ S EA+ + + +EV++
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 281 DSKKK-----------KMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILK-QAPDNEIT 328
K K + K PE E P + ++P K K K K+ + ++P+ +
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 329 IKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVK 376
K K A+ + E +S E + + + +K+PT + K K
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAE---VKSPEKAKSPTKEEAKSPEK 651
Score = 45.1 bits (105), Expect = 1e-04
Identities = 56/234 (23%), Positives = 84/234 (35%), Gaps = 20/234 (8%)
Query: 138 SEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERK---EE 194
S A PV KE+ + P + A+ TK A + A + E K+ + K +
Sbjct: 614 SPAEAKSPV-KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 195 RQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEV--PEANGSAGKRSKKK 252
K ++ K +K E K+ K E EE PE S K K
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 253 KQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDD----------- 301
++ S +EEA+ K K D K + K P E P D
Sbjct: 733 PEKAKSPVKEEAK-SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE 791
Query: 302 --EAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEE 353
++P K K K KA K+ P E ++++ Q V + ++EEE
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/229 (21%), Positives = 86/229 (37%), Gaps = 10/229 (4%)
Query: 81 ISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEA 140
+ E +K P + L E A + KK + ++ +K K + + E
Sbjct: 789 VKEEVKSPEKAKS--PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846
Query: 141 SNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRK 200
+ + P K ++++ P E K + AVE+ E K +KEE + K+K
Sbjct: 847 APATP--KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK--VEAKKEEAEDKKK 902
Query: 201 REKKELKLENHQENSRNQKPKKR---KKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKD 257
E + E + KPK++ K + D +A P A K K+ K
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962
Query: 258 SASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAK 306
EE+ + A K K + + K K + E + +D + P K
Sbjct: 963 KKPEEKPKTEA-KAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 39.7 bits (91), Expect = 0.005
Identities = 67/289 (23%), Positives = 110/289 (38%), Gaps = 31/289 (10%)
Query: 69 KGDIKQQAWI-QKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNE 127
K +K++A +K +K SP+ + E+ D V +AK K
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD-VKSPEAK------TPAKEEAR 775
Query: 128 SILDQVWNIFSEASNSEPVNKEQDQRPLHPVAN-PHAEISTKVPASKVKDAVEQQGEVKK 186
S D+ E + E+ + PL A P EI K E+ EVK
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV 835
Query: 187 NKRERKEERQKKRKREKKELKLENHQENSRNQ---KPKKRKKGQEADLEAGGEEVPEANG 243
+ +K E +K K E K ++ +E + + KPK +K + A E P+ +
Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA------VEKPKESK 889
Query: 244 SAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEA 303
K+ + + ++K E+EA EV+ D+K K E E + E D+A
Sbjct: 890 VEAKKEEAEDKKKVPTPEKEAPAKV--------EVKEDAKPK-----EKTEVAKKEPDDA 936
Query: 304 PAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEE 352
AK +A ++ E KK +K + D+ S+E
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Score = 38.5 bits (88), Expect = 0.010
Identities = 56/281 (19%), Positives = 109/281 (38%), Gaps = 19/281 (6%)
Query: 52 ISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKK 111
++E+++ K EGK +G +++A + E K P E S +
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEA--EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527
Query: 112 AKFQNWMKNSLKVHNE-SILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVP 170
A+ ++ K K E ++ + E + S P K ++ A + K P
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587
Query: 171 ASKVKDAVEQQGEVKKNKRERKEERQ---------KKRKREKKELKLENHQENSRNQKPK 221
A + + + +K K KEE + K+ + E+K ++ ++ K
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647
Query: 222 KRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETD 281
+K + + E + PE S K K ++ S + EA+ ++ S V+ +
Sbjct: 648 SPEKAKSPEKEEA--KSPEKAKSPVKAEAKSPEKAKSPVKAEAK----SPEKAKSPVKEE 701
Query: 282 SKK-KKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQ 321
+K +K K P E PE ++P K + K+ +K+
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Score = 31.2 bits (69), Expect = 1.6
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 2/126 (1%)
Query: 163 AEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKK 222
AE KVP + K+A + EVK++ + +++ K++ + + K + + P+K
Sbjct: 897 AEDKKKVPTPE-KEAPAKV-EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954
Query: 223 RKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDS 282
+ +E + + EA ++ K+ K A + E ++ + E T+
Sbjct: 955 KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Query: 283 KKKKMK 288
K K K
Sbjct: 1015 KAAKGK 1020
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 19/119 (15%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
++ ++++ VK+ RE++ ER+K+R++EK + + K+R+K +E D E
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEK--------ERGKNKDRDKEREKDREKDKEKD 432
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHP 293
E R ++K+ KD E+E K + + E D K+KK K P
Sbjct: 433 RE-----------REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Score = 48.9 bits (115), Expect = 7e-06
Identities = 36/174 (20%), Positives = 79/174 (45%), Gaps = 10/174 (5%)
Query: 162 HAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPK 221
H+ K K+K+ + + ++ +RER++ER+K+++R K + + + +++ K K
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 222 KRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETD 281
R++ +E + E ++ E ++ K+K++ KD + E + + K+ R
Sbjct: 432 DREREREKEHEKDRDKEKEK-----EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486
Query: 282 SKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKK 335
S++ + E +P K TIK ++P KK +K+
Sbjct: 487 SRRSRSSSRERRRRRSRSSSRSPRTSK-----TIKRKSSRSPSPRSRNKKDKKR 535
Score = 46.6 bits (109), Expect = 4e-05
Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 8/208 (3%)
Query: 172 SKVKDAVEQQGEVKKNK---RERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQE 228
SK + + + K+++ R R R + R+++++ K + + + ++ K R +
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373
Query: 229 ADLEAG-GEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
D E++ E K +K+++R+ +E+ R GK K R E E D +K K
Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER---GKNKDRDKEREKDREKDKE 430
Query: 288 KLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEH 347
K E E E D K K K + + +E K + + + Y +
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 490
Query: 348 HRSEEELLVIFNKKISKNP-TFKLLKDK 374
S E ++ S++P T K +K K
Sbjct: 491 RSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Score = 42.7 bits (99), Expect = 5e-04
Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 8/149 (5%)
Query: 162 HAEISTKVPASKVKDAVEQQGEVKKNK--RERKEERQKKRKREKKELKLENHQENSRNQK 219
H S S+ KD + KK RER++ R + R+K++ E +E R K
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER-VK 391
Query: 220 PKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVE 279
K R+K +E + E E+ N K ++K + KD + E K R E E
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKE-REKDREKDKEKDREREREKEHEKDRDKEKE 450
Query: 280 TDSKKKKMKLPEHPEGGEPEDDEAPAKGK 308
+ K+K E + E DE K K
Sbjct: 451 KEQDKEK----EREKDRSKEIDEKRKKDK 475
Score = 37.4 bits (85), Expect = 0.022
Identities = 28/147 (19%), Positives = 58/147 (39%), Gaps = 5/147 (3%)
Query: 165 ISTKVPASKVKDAVEQQGEVKKNKRERKEERQK---KRKREKKELKLENHQENSRNQKPK 221
IS + K + G + + R + K +RKR + + + +H + QK +
Sbjct: 289 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR 348
Query: 222 KRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETD 281
+R K E + S + K+K ++ E+E + K R E E +
Sbjct: 349 RRSKSPHKKRSKSRERRKSRSRSHSR--DKRKDTREKIKEKERVKEKDREKEREREKERE 406
Query: 282 SKKKKMKLPEHPEGGEPEDDEAPAKGK 308
+K++ K + + E + ++ K +
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDR 433
Score = 32.7 bits (73), Expect = 0.55
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLE-AGGEEVPEANG 243
++ +R R R + + K + SRN+K KKR+K ++ E E
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 556
Query: 244 SAGKRSKKKKQRKDSASEEE 263
S+ R K+K K+S S +E
Sbjct: 557 SSNDRDGKEKLEKNSTSLKE 576
Score = 30.8 bits (68), Expect = 2.1
Identities = 30/134 (22%), Positives = 57/134 (42%), Gaps = 19/134 (14%)
Query: 185 KKNKRERKEERQK------KRKREKKEL---KLENHQENSRNQKPKKRKKGQEADLEAGG 235
K+ +E++ E+ + KRK++KK + N SR+ ++R++ + +
Sbjct: 451 KEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPR 510
Query: 236 EEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKR------RHSEVETDSKKKKMK- 288
S+ S + + +KD E+E + +R+R R S + D K+K K
Sbjct: 511 TSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 570
Query: 289 ---LPEHPEGGEPE 299
L E EP+
Sbjct: 571 STSLKEKEHNKEPD 584
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 19/119 (15%)
Query: 175 KDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
++ ++++ VK+ RE++ ER+K+R++EK + + K+R+K +E D E
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEK--------ERGKNKDRDKEREKDREKDKEKD 316
Query: 235 GEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHP 293
E R ++K+ KD E+E K + + E D K+KK K P
Sbjct: 317 RE-----------REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Score = 48.9 bits (115), Expect = 7e-06
Identities = 36/174 (20%), Positives = 79/174 (45%), Gaps = 10/174 (5%)
Query: 162 HAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPK 221
H+ K K+K+ + + ++ +RER++ER+K+++R K + + + +++ K K
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 222 KRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETD 281
R++ +E + E ++ E ++ K+K++ KD + E + + K+ R
Sbjct: 316 DREREREKEHEKDRDKEKEK-----EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370
Query: 282 SKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKK 335
S++ + E +P K TIK ++P KK +K+
Sbjct: 371 SRRSRSSSRERRRRRSRSSSRSPRTSK-----TIKRKSSRSPSPRSRNKKDKKR 419
Score = 46.6 bits (109), Expect = 4e-05
Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 8/208 (3%)
Query: 172 SKVKDAVEQQGEVKKNK---RERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQE 228
SK + + + K+++ R R R + R+++++ K + + + ++ K R +
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257
Query: 229 ADLEAG-GEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKM 287
D E++ E K +K+++R+ +E+ R GK K R E E D +K K
Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER---GKNKDRDKEREKDREKDKE 314
Query: 288 KLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEH 347
K E E E D K K K + + +E K + + + Y +
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 374
Query: 348 HRSEEELLVIFNKKISKNP-TFKLLKDK 374
S E ++ S++P T K +K K
Sbjct: 375 RSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Score = 42.7 bits (99), Expect = 5e-04
Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 8/149 (5%)
Query: 162 HAEISTKVPASKVKDAVEQQGEVKKNK--RERKEERQKKRKREKKELKLENHQENSRNQK 219
H S S+ KD + KK RER++ R + R+K++ E +E R K
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER-VK 275
Query: 220 PKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVE 279
K R+K +E + E E+ N K ++K + KD + E K R E E
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKE-REKDREKDKEKDREREREKEHEKDRDKEKE 334
Query: 280 TDSKKKKMKLPEHPEGGEPEDDEAPAKGK 308
+ K+K E + E DE K K
Sbjct: 335 KEQDKEK----EREKDRSKEIDEKRKKDK 359
Score = 37.4 bits (85), Expect = 0.022
Identities = 28/147 (19%), Positives = 58/147 (39%), Gaps = 5/147 (3%)
Query: 165 ISTKVPASKVKDAVEQQGEVKKNKRERKEERQK---KRKREKKELKLENHQENSRNQKPK 221
IS + K + G + + R + K +RKR + + + +H + QK +
Sbjct: 173 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR 232
Query: 222 KRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETD 281
+R K E + S + K+K ++ E+E + K R E E +
Sbjct: 233 RRSKSPHKKRSKSRERRKSRSRSHSR--DKRKDTREKIKEKERVKEKDREKEREREKERE 290
Query: 282 SKKKKMKLPEHPEGGEPEDDEAPAKGK 308
+K++ K + + E + ++ K +
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDR 317
Score = 32.7 bits (73), Expect = 0.55
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 185 KKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLE-AGGEEVPEANG 243
++ +R R R + + K + SRN+K KKR+K ++ E E
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 440
Query: 244 SAGKRSKKKKQRKDSASEEE 263
S+ R K+K K+S S +E
Sbjct: 441 SSNDRDGKEKLEKNSTSLKE 460
Score = 30.8 bits (68), Expect = 2.1
Identities = 30/134 (22%), Positives = 57/134 (42%), Gaps = 19/134 (14%)
Query: 185 KKNKRERKEERQK------KRKREKKEL---KLENHQENSRNQKPKKRKKGQEADLEAGG 235
K+ +E++ E+ + KRK++KK + N SR+ ++R++ + +
Sbjct: 335 KEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPR 394
Query: 236 EEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKR------RHSEVETDSKKKKMK- 288
S+ S + + +KD E+E + +R+R R S + D K+K K
Sbjct: 395 TSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 454
Query: 289 ---LPEHPEGGEPE 299
L E EP+
Sbjct: 455 STSLKEKEHNKEPD 468
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 14/175 (8%)
Query: 176 DAVEQQGEVKKNKRERKEERQKKRKRE-KKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
D V++ E K+ R+ E + +R+RE ++EL+ QE ++ ++R EA+ +G
Sbjct: 308 DEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSG 367
Query: 235 ---GEEVPEANGSAGKRSKKKKQR-----KDSASEEEARVGAGKRKRRHSEVETD----- 281
G+E+ E + KR +K + R DS E E A K ++ T+
Sbjct: 368 GSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKP 427
Query: 282 SKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKV 336
+K+K PE + +P E K + K K+ P E ++KL ++
Sbjct: 428 GQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEI 482
Score = 32.7 bits (73), Expect = 0.55
Identities = 49/230 (21%), Positives = 78/230 (33%), Gaps = 31/230 (13%)
Query: 105 DNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRP-LHPVANPHA 163
D P K K + N K NE + + N + S PV+ + P +P A
Sbjct: 57 DLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDA 116
Query: 164 EIS---------TKVPASKVKDAVEQQGEVKKN------KRERKEERQKKRKREKKELK- 207
+ T V A+ D +E + K+ KR+ + KR +K
Sbjct: 117 DEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSD 176
Query: 208 ------LENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
+ +ENS + ++ Q+ E G G R KKKK S S+
Sbjct: 177 LDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGR-KKKKAPSASDSD 235
Query: 262 EEARVGAGK-------RKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAP 304
+A K R S + S + + + P G +P + P
Sbjct: 236 SKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLP 285
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 14/175 (8%)
Query: 176 DAVEQQGEVKKNKRERKEERQKKRKRE-KKELKLENHQENSRNQKPKKRKKGQEADLEAG 234
D V++ E K+ R+ E + +R+RE ++EL+ QE ++ ++R EA+ +G
Sbjct: 308 DEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSG 367
Query: 235 ---GEEVPEANGSAGKRSKKKKQR-----KDSASEEEARVGAGKRKRRHSEVETD----- 281
G+E+ E + KR +K + R DS E E A K ++ T+
Sbjct: 368 GSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKP 427
Query: 282 SKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKV 336
+K+K PE + +P E K + K K+ P E ++KL ++
Sbjct: 428 GQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEI 482
Score = 32.7 bits (73), Expect = 0.55
Identities = 49/230 (21%), Positives = 78/230 (33%), Gaps = 31/230 (13%)
Query: 105 DNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRP-LHPVANPHA 163
D P K K + N K NE + + N + S PV+ + P +P A
Sbjct: 57 DLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDA 116
Query: 164 EIS---------TKVPASKVKDAVEQQGEVKKN------KRERKEERQKKRKREKKELK- 207
+ T V A+ D +E + K+ KR+ + KR +K
Sbjct: 117 DEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSD 176
Query: 208 ------LENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
+ +ENS + ++ Q+ E G G R KKKK S S+
Sbjct: 177 LDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGR-KKKKAPSASDSD 235
Query: 262 EEARVGAGK-------RKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAP 304
+A K R S + S + + + P G +P + P
Sbjct: 236 SKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLP 285
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,990,791
Number of Sequences: 37866
Number of extensions: 839111
Number of successful extensions: 17722
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 577
Number of HSP's successfully gapped in prelim test: 844
Number of HSP's that attempted gapping in prelim test: 6366
Number of HSP's gapped (non-prelim): 6028
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.