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Search of human proteins with 224586907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224586907 tubulointerstitial nephritis antigen [Homo
sapiens]
(476 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 1030 0.0
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa... 436 e-122
gi|22538437 cathepsin B preproprotein [Homo sapiens] 138 1e-32
gi|22538435 cathepsin B preproprotein [Homo sapiens] 138 1e-32
gi|22538433 cathepsin B preproprotein [Homo sapiens] 138 1e-32
gi|22538431 cathepsin B preproprotein [Homo sapiens] 138 1e-32
gi|4503139 cathepsin B preproprotein [Homo sapiens] 138 1e-32
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] 127 3e-29
gi|23110960 cathepsin L2 preproprotein [Homo sapiens] 90 4e-18
gi|22538442 cathepsin Z preproprotein [Homo sapiens] 88 2e-17
gi|4503151 cathepsin K preproprotein [Homo sapiens] 84 2e-16
gi|23110957 cathepsin H isoform b precursor [Homo sapiens] 84 4e-16
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 84 4e-16
gi|23110962 cathepsin S preproprotein [Homo sapiens] 81 2e-15
gi|22202619 cathepsin L1 preproprotein [Homo sapiens] 78 2e-14
gi|4503155 cathepsin L1 preproprotein [Homo sapiens] 78 2e-14
gi|4557501 cathepsin O preproprotein [Homo sapiens] 73 5e-13
gi|23110964 cathepsin W preproprotein [Homo sapiens] 71 2e-12
gi|6042196 cathepsin F [Homo sapiens] 54 3e-07
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 50 3e-06
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 50 3e-06
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 50 3e-06
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 50 3e-06
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 50 3e-06
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 50 3e-06
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 48 2e-05
gi|161019170 mucin 5AC [Homo sapiens] 44 4e-04
gi|116284392 mucin 2 precursor [Homo sapiens] 44 4e-04
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 44 4e-04
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 44 4e-04
>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
Length = 476
Score = 1030 bits (2664), Expect = 0.0
Identities = 476/476 (100%), Positives = 476/476 (100%)
Query: 1 MWTGYKILIFSYLTTEIWMEKQYLSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNF 60
MWTGYKILIFSYLTTEIWMEKQYLSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNF
Sbjct: 1 MWTGYKILIFSYLTTEIWMEKQYLSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNF 60
Query: 61 GCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGC 120
GCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGC
Sbjct: 61 GCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGC 120
Query: 121 FKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFW 180
FKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFW
Sbjct: 121 FKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFW 180
Query: 181 GMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNC 240
GMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNC
Sbjct: 181 GMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNC 240
Query: 241 AASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRG 300
AASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRG
Sbjct: 241 AASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRG 300
Query: 301 LVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSN 360
LVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSN
Sbjct: 301 LVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSN 360
Query: 361 ETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGT 420
ETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGT
Sbjct: 361 ETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGT 420
Query: 421 LRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP 476
LRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP
Sbjct: 421 LRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP 476
>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
sapiens]
Length = 467
Score = 436 bits (1122), Expect = e-122
Identities = 210/426 (49%), Positives = 274/426 (64%), Gaps = 12/426 (2%)
Query: 54 GQYCRNFG-CCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHT 112
G+YC+ CC R D C + A +CYCD FC+R SDCCPD+ FC PP
Sbjct: 45 GRYCQEQDLCCRGRADDCALPYLGA--ICYCDLFCNRTVSDCCPDFWDFCLGV---PPPF 99
Query: 113 QPWYPEGCFKDGQHYEEGSVIKENCNSCTCS-GQQWKCSQHVCLVRSELIEQVNKGDYGW 171
P +GC G+ Y +NCN CTC +QW+C Q CLV ++I+ +N+G+YGW
Sbjct: 100 PPI--QGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGW 157
Query: 172 TAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWT 231
A N+S FWGMTL++G ++RLGT+ PS +++M+E+ L LP F AS KWP
Sbjct: 158 QAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLI 217
Query: 232 HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDR 291
H PLDQ NCA SWAFSTA+VA+DR++I S G T LSPQNL+SC + GC G +D
Sbjct: 218 HEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDG 277
Query: 292 AWWYLRKRGLVSHACYPLF---KDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRI 348
AWW+LR+RG+VS CYP +D+ C M SR+ GRGKR AT CPN+ +N I
Sbjct: 278 AWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDI 337
Query: 349 YQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKL 408
YQ +P YR+ SN+ EIMKE+M+NGPVQA+M+V EDFF YK GIY H + E+YR+
Sbjct: 338 YQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRH 397
Query: 409 QTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWG 468
TH+VK+TGWG G+ K+W AANSWG +WGE G+FRI+RGVNE DIE ++ WG
Sbjct: 398 GTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWG 457
Query: 469 QLTSSD 474
++ D
Sbjct: 458 RVGMED 463
>gi|22538437 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 138 bits (347), Expect = 1e-32
Identities = 97/326 (29%), Positives = 143/326 (43%), Gaps = 46/326 (14%)
Query: 159 ELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLP 218
EL+ VNK + W A + F+ + + K GT P T L LP
Sbjct: 29 ELVNYVNKRNTTWQAGH--NFYNVDMSY-LKRLCGTFLGGPKPPQRVMFTEDLK----LP 81
Query: 219 EFFVASYKWPGWT--HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISC 276
F A +WP DQ +C + WAF +DRI I + + +S ++L++C
Sbjct: 82 ASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC 141
Query: 277 CAKN-RHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHAT 335
C GCN G AW + ++GLVS Y ++ GC S + +
Sbjct: 142 CGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE-------SHVGCRPYSIPPCEHHVNGS 194
Query: 336 KP-CPNNVEKSNRIYQCSP---------------PYRVSSNETEIMKEIMQNGPVQAIMQ 379
+P C + C P Y VS++E +IM EI +NGPV+
Sbjct: 195 RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254
Query: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439
V DF YK+G+Y+HVT + HA+++ GWG G +W+ ANSW
Sbjct: 255 VYSDFLLYKSGVYQHVTG--------EMMGGHAIRILGWGVENGT-----PYWLVANSWN 301
Query: 440 KSWGENGYFRILRGVNESDIEKLIIA 465
WG+NG+F+ILRG + IE ++A
Sbjct: 302 TDWGDNGFFKILRGQDHCGIESEVVA 327
>gi|22538435 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 138 bits (347), Expect = 1e-32
Identities = 97/326 (29%), Positives = 143/326 (43%), Gaps = 46/326 (14%)
Query: 159 ELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLP 218
EL+ VNK + W A + F+ + + K GT P T L LP
Sbjct: 29 ELVNYVNKRNTTWQAGH--NFYNVDMSY-LKRLCGTFLGGPKPPQRVMFTEDLK----LP 81
Query: 219 EFFVASYKWPGWT--HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISC 276
F A +WP DQ +C + WAF +DRI I + + +S ++L++C
Sbjct: 82 ASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC 141
Query: 277 CAKN-RHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHAT 335
C GCN G AW + ++GLVS Y ++ GC S + +
Sbjct: 142 CGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE-------SHVGCRPYSIPPCEHHVNGS 194
Query: 336 KP-CPNNVEKSNRIYQCSP---------------PYRVSSNETEIMKEIMQNGPVQAIMQ 379
+P C + C P Y VS++E +IM EI +NGPV+
Sbjct: 195 RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254
Query: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439
V DF YK+G+Y+HVT + HA+++ GWG G +W+ ANSW
Sbjct: 255 VYSDFLLYKSGVYQHVTG--------EMMGGHAIRILGWGVENGT-----PYWLVANSWN 301
Query: 440 KSWGENGYFRILRGVNESDIEKLIIA 465
WG+NG+F+ILRG + IE ++A
Sbjct: 302 TDWGDNGFFKILRGQDHCGIESEVVA 327
>gi|22538433 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 138 bits (347), Expect = 1e-32
Identities = 97/326 (29%), Positives = 143/326 (43%), Gaps = 46/326 (14%)
Query: 159 ELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLP 218
EL+ VNK + W A + F+ + + K GT P T L LP
Sbjct: 29 ELVNYVNKRNTTWQAGH--NFYNVDMSY-LKRLCGTFLGGPKPPQRVMFTEDLK----LP 81
Query: 219 EFFVASYKWPGWT--HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISC 276
F A +WP DQ +C + WAF +DRI I + + +S ++L++C
Sbjct: 82 ASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC 141
Query: 277 CAKN-RHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHAT 335
C GCN G AW + ++GLVS Y ++ GC S + +
Sbjct: 142 CGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE-------SHVGCRPYSIPPCEHHVNGS 194
Query: 336 KP-CPNNVEKSNRIYQCSP---------------PYRVSSNETEIMKEIMQNGPVQAIMQ 379
+P C + C P Y VS++E +IM EI +NGPV+
Sbjct: 195 RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254
Query: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439
V DF YK+G+Y+HVT + HA+++ GWG G +W+ ANSW
Sbjct: 255 VYSDFLLYKSGVYQHVTG--------EMMGGHAIRILGWGVENGT-----PYWLVANSWN 301
Query: 440 KSWGENGYFRILRGVNESDIEKLIIA 465
WG+NG+F+ILRG + IE ++A
Sbjct: 302 TDWGDNGFFKILRGQDHCGIESEVVA 327
>gi|22538431 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 138 bits (347), Expect = 1e-32
Identities = 97/326 (29%), Positives = 143/326 (43%), Gaps = 46/326 (14%)
Query: 159 ELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLP 218
EL+ VNK + W A + F+ + + K GT P T L LP
Sbjct: 29 ELVNYVNKRNTTWQAGH--NFYNVDMSY-LKRLCGTFLGGPKPPQRVMFTEDLK----LP 81
Query: 219 EFFVASYKWPGWT--HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISC 276
F A +WP DQ +C + WAF +DRI I + + +S ++L++C
Sbjct: 82 ASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC 141
Query: 277 CAKN-RHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHAT 335
C GCN G AW + ++GLVS Y ++ GC S + +
Sbjct: 142 CGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE-------SHVGCRPYSIPPCEHHVNGS 194
Query: 336 KP-CPNNVEKSNRIYQCSP---------------PYRVSSNETEIMKEIMQNGPVQAIMQ 379
+P C + C P Y VS++E +IM EI +NGPV+
Sbjct: 195 RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254
Query: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439
V DF YK+G+Y+HVT + HA+++ GWG G +W+ ANSW
Sbjct: 255 VYSDFLLYKSGVYQHVTG--------EMMGGHAIRILGWGVENGT-----PYWLVANSWN 301
Query: 440 KSWGENGYFRILRGVNESDIEKLIIA 465
WG+NG+F+ILRG + IE ++A
Sbjct: 302 TDWGDNGFFKILRGQDHCGIESEVVA 327
>gi|4503139 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 138 bits (347), Expect = 1e-32
Identities = 97/326 (29%), Positives = 143/326 (43%), Gaps = 46/326 (14%)
Query: 159 ELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLP 218
EL+ VNK + W A + F+ + + K GT P T L LP
Sbjct: 29 ELVNYVNKRNTTWQAGH--NFYNVDMSY-LKRLCGTFLGGPKPPQRVMFTEDLK----LP 81
Query: 219 EFFVASYKWPGWT--HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISC 276
F A +WP DQ +C + WAF +DRI I + + +S ++L++C
Sbjct: 82 ASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC 141
Query: 277 CAKN-RHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHAT 335
C GCN G AW + ++GLVS Y ++ GC S + +
Sbjct: 142 CGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE-------SHVGCRPYSIPPCEHHVNGS 194
Query: 336 KP-CPNNVEKSNRIYQCSP---------------PYRVSSNETEIMKEIMQNGPVQAIMQ 379
+P C + C P Y VS++E +IM EI +NGPV+
Sbjct: 195 RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254
Query: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439
V DF YK+G+Y+HVT + HA+++ GWG G +W+ ANSW
Sbjct: 255 VYSDFLLYKSGVYQHVTG--------EMMGGHAIRILGWGVENGT-----PYWLVANSWN 301
Query: 440 KSWGENGYFRILRGVNESDIEKLIIA 465
WG+NG+F+ILRG + IE ++A
Sbjct: 302 TDWGDNGFFKILRGQDHCGIESEVVA 327
>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
Length = 463
Score = 127 bits (318), Expect = 3e-29
Identities = 98/340 (28%), Positives = 146/340 (42%), Gaps = 45/340 (13%)
Query: 138 NSCTCSGQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLED------GFKFR 191
N+ Q K S + ++ +N WTA Y ++ +TL D G +
Sbjct: 152 NTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRK 211
Query: 192 LGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASV 251
+ P+P+ + + LP + D ++ P +Q +C + ++F++ +
Sbjct: 212 IPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSP-----VRNQASCGSCYSFASMGM 266
Query: 252 AADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSG-SIDRAWWYLRKRGLVSHACYPLF 310
RI I + T LSPQ ++SC ++ GC G A Y + GLV AC+P
Sbjct: 267 LEARIRILTNNSQTPILSPQEVVSC-SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY- 324
Query: 311 KDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPY----RVSSNETEIMK 366
T++ C M E R Y Y NE +
Sbjct: 325 ---TGTDSPCKMK-------------------EDCFRYYSSEYHYVGGFYGGCNEALMKL 362
Query: 367 EIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQG 426
E++ +GP+ +V +DF HYK GIY H T + +L HAV L G+GT A G
Sbjct: 363 ELVHHGPMAVAFEVYDDFLHYKKGIYHH-TGLRDPFNPF-ELTNHAVLLVGYGT-DSASG 419
Query: 427 QKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAA 466
+WI NSWG WGENGYFRI RG +E IE + +AA
Sbjct: 420 MD--YWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAA 457
>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
Length = 334
Score = 90.1 bits (222), Expect = 4e-18
Identities = 83/305 (27%), Positives = 127/305 (41%), Gaps = 61/305 (20%)
Query: 163 QVNKGDYGWTAQNYSQFWGMTLED---------GFKFRLGTLPPSPMLLSMNEMTASLPA 213
+ ++G +G+T + F MT E+ KFR G + P+ L LP
Sbjct: 65 EYSQGKHGFTMA-MNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-------LPK 116
Query: 214 TTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273
+ D ++ G+ +QK C + WAFS A+ A + + G+ + LS QNL
Sbjct: 117 SVD--------WRKKGYVTPVKNQKQCGSCWAFS-ATGALEGQMFRKTGKLVS-LSEQNL 166
Query: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331
+ C + GCN G + RA+ Y+++ G L S YP A + C
Sbjct: 167 VDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYV----AVDEIC----------- 211
Query: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFH-YKTG 390
K P N ++ + P E +MK + GP+ M F YK+G
Sbjct: 212 ----KYRPENSVANDTGFTVVAP----GKEKALMKAVATVGPISVAMDAGHSSFQFYKSG 263
Query: 391 IYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRI 450
IY ++K + H V + G+G GA K+W+ NSWG WG NGY +I
Sbjct: 264 IYFEPDCSSKNLD-------HGVLVVGYG-FEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315
Query: 451 LRGVN 455
+ N
Sbjct: 316 AKDKN 320
>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
Length = 303
Score = 87.8 bits (216), Expect = 2e-17
Identities = 61/213 (28%), Positives = 94/213 (44%), Gaps = 26/213 (12%)
Query: 240 CAASWAFSTASVAADRIAIQSKGRYTANL-SPQNLISCCAKNRHGCNSGSIDRAWWYLRK 298
C + WA ++ S ADRI I+ KG + + L S QN+I C N C G+ W Y +
Sbjct: 89 CGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDC--GNAGSCEGGNDLSVWDYAHQ 146
Query: 299 RGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVS 358
G+ C + A + C ++ G + K C + ++ +++ Y
Sbjct: 147 HGIPDETC----NNYQAKDQECDKFNQC---GTCNEFKEC--HAIRNYTLWRVGD-YGSL 196
Query: 359 SNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGW 418
S ++M EI NGP+ + E +Y GIY T + H V + GW
Sbjct: 197 SGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYIN--------HVVSVAGW 248
Query: 419 GTLRGAQGQKEKFWIAANSWGKSWGENGYFRIL 451
G G + +WI NSWG+ WGE G+ RI+
Sbjct: 249 GISDGTE-----YWIVRNSWGEPWGERGWLRIV 276
>gi|4503151 cathepsin K preproprotein [Homo sapiens]
Length = 329
Score = 84.3 bits (207), Expect = 2e-16
Identities = 69/236 (29%), Positives = 104/236 (44%), Gaps = 42/236 (17%)
Query: 225 YKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGC 284
Y+ G+ +Q C + WAFS SV A ++ K NLSPQNL+ C ++N GC
Sbjct: 121 YRKKGYVTPVKNQGQCGSCWAFS--SVGALEGQLKKKTGKLLNLSPQNLVDCVSEN-DGC 177
Query: 285 NSGSIDRAWWYLRK-RGLVSHACYPLF-KDQNATNNGCAMASRSDGRGKRHATKPCPNNV 342
G + A+ Y++K RG+ S YP ++++ N A++ G
Sbjct: 178 GGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRG-------------- 223
Query: 343 EKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQ-AIMQVREDFFHYKTGIYRHVTSTNKE 401
Y+ P NE + + + + GPV AI F Y G+Y + S N +
Sbjct: 224 ------YREIP----EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVY-YDESCNSD 272
Query: 402 SEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNES 457
+ HAV G+G +G K WI NSWG++WG GY + R N +
Sbjct: 273 N------LNHAVLAVGYGIQKG-----NKHWIIKNSWGENWGNKGYILMARNKNNA 317
>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
Length = 323
Score = 83.6 bits (205), Expect = 4e-16
Identities = 69/223 (30%), Positives = 95/223 (42%), Gaps = 39/223 (17%)
Query: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAK-NRHGCNSGSIDRAWW 294
+Q C + W FST IAI + G+ + L+ Q L+ C N HGC G +A+
Sbjct: 122 NQGACGSCWTFSTTGALESAIAIAT-GKMLS-LAEQQLVDCAQDFNNHGCQGGLPSQAFE 179
Query: 295 Y-LRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSN-RIYQCS 352
Y L +G++ YP DG K K + +N IY
Sbjct: 180 YILYNKGIMGEDTYPY--------------QGKDGYCKFQPGKAIGFVKDVANITIY--- 222
Query: 353 PPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHA 412
+E +++ + PV +V +DF Y+TGIY TS +K +K HA
Sbjct: 223 -------DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS-TSCHKTPDKVN----HA 270
Query: 413 VKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
V G+G G +WI NSWG WG NGYF I RG N
Sbjct: 271 VLAVGYGEKNGIP-----YWIVKNSWGPQWGMNGYFLIERGKN 308
>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
Length = 335
Score = 83.6 bits (205), Expect = 4e-16
Identities = 69/223 (30%), Positives = 95/223 (42%), Gaps = 39/223 (17%)
Query: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAK-NRHGCNSGSIDRAWW 294
+Q C + W FST IAI + G+ + L+ Q L+ C N HGC G +A+
Sbjct: 134 NQGACGSCWTFSTTGALESAIAIAT-GKMLS-LAEQQLVDCAQDFNNHGCQGGLPSQAFE 191
Query: 295 Y-LRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSN-RIYQCS 352
Y L +G++ YP DG K K + +N IY
Sbjct: 192 YILYNKGIMGEDTYPY--------------QGKDGYCKFQPGKAIGFVKDVANITIY--- 234
Query: 353 PPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHA 412
+E +++ + PV +V +DF Y+TGIY TS +K +K HA
Sbjct: 235 -------DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS-TSCHKTPDKVN----HA 282
Query: 413 VKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
V G+G G +WI NSWG WG NGYF I RG N
Sbjct: 283 VLAVGYGEKNGIP-----YWIVKNSWGPQWGMNGYFLIERGKN 320
>gi|23110962 cathepsin S preproprotein [Homo sapiens]
Length = 331
Score = 81.3 bits (199), Expect = 2e-15
Identities = 63/221 (28%), Positives = 97/221 (43%), Gaps = 44/221 (19%)
Query: 237 QKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKN--RHGCNSGSIDRAWW 294
Q +C A WAFS +V A ++ K +LS QNL+ C + GCN G + A+
Sbjct: 133 QGSCGACWAFS--AVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQ 190
Query: 295 YL-RKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSP 353
Y+ +G+ S A YP A + C S+ R CS
Sbjct: 191 YIIDNKGIDSDASYPY----KAMDQKCQYDSKY--------------------RAATCSK 226
Query: 354 PYRVSSNETEIMKEIMQN-GPVQAIMQVRE-DFFHYKTGIYRHVTSTNKESEKYRKLQTH 411
+ +++KE + N GPV + R FF Y++G+Y + T + H
Sbjct: 227 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVN--------H 278
Query: 412 AVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILR 452
V + G+G L G +++W+ NSWG ++GE GY R+ R
Sbjct: 279 GVLVVGYGDLNG-----KEYWLVKNSWGHNFGEEGYIRMAR 314
>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 78.2 bits (191), Expect = 2e-14
Identities = 68/251 (27%), Positives = 104/251 (41%), Gaps = 59/251 (23%)
Query: 218 PEFFVA--SYKW--PGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273
P F+ A S W G+ +Q C + WAFS A+ A + + GR + LS QNL
Sbjct: 109 PLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFS-ATGALEGQMFRKTGRLIS-LSEQNL 166
Query: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331
+ C + GCN G +D A+ Y++ G L S YP AT C
Sbjct: 167 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPY----EATEESC----------- 211
Query: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSN---------ETEIMKEIMQNGPVQ-AIMQVR 381
+ +P Y V+++ E +MK + GP+ AI
Sbjct: 212 ------------------KYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGH 253
Query: 382 EDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKS 441
E F YK GIY ++++ + H V + G+G + K+W+ NSWG+
Sbjct: 254 ESFLFYKEGIYFEPDCSSEDMD-------HGVLVVGYG-FESTESDNNKYWLVKNSWGEE 305
Query: 442 WGENGYFRILR 452
WG GY ++ +
Sbjct: 306 WGMGGYVKMAK 316
>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 78.2 bits (191), Expect = 2e-14
Identities = 68/251 (27%), Positives = 104/251 (41%), Gaps = 59/251 (23%)
Query: 218 PEFFVA--SYKW--PGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273
P F+ A S W G+ +Q C + WAFS A+ A + + GR + LS QNL
Sbjct: 109 PLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFS-ATGALEGQMFRKTGRLIS-LSEQNL 166
Query: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331
+ C + GCN G +D A+ Y++ G L S YP AT C
Sbjct: 167 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPY----EATEESC----------- 211
Query: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSN---------ETEIMKEIMQNGPVQ-AIMQVR 381
+ +P Y V+++ E +MK + GP+ AI
Sbjct: 212 ------------------KYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGH 253
Query: 382 EDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKS 441
E F YK GIY ++++ + H V + G+G + K+W+ NSWG+
Sbjct: 254 ESFLFYKEGIYFEPDCSSEDMD-------HGVLVVGYG-FESTESDNNKYWLVKNSWGEE 305
Query: 442 WGENGYFRILR 452
WG GY ++ +
Sbjct: 306 WGMGGYVKMAK 316
>gi|4557501 cathepsin O preproprotein [Homo sapiens]
Length = 321
Score = 73.2 bits (178), Expect = 5e-13
Identities = 67/222 (30%), Positives = 92/222 (41%), Gaps = 40/222 (18%)
Query: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
+Q+ C WAFS AI KG+ +LS Q +I C + N +GCN GS A +
Sbjct: 125 NQQMCGGCWAFSVVGAVESAYAI--KGKPLEDLSVQQVIDC-SYNNYGCNGGSTLNALNW 181
Query: 296 LRKRG--LVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSP 353
L K LV + YP FK QN C S S S +
Sbjct: 182 LNKMQVKLVKDSEYP-FKAQNGL---CHYFSGSH-----------------SGFSIKGYS 220
Query: 354 PYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Y S E E+ K ++ GP+ I+ + Y GI +H S+ + + HAV
Sbjct: 221 AYDFSDQEDEMAKALLTFGPLVVIVDA-VSWQDYLGGIIQHHCSSGEAN--------HAV 271
Query: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
+TG+ +WI NSWG SWG +GY + G N
Sbjct: 272 LITGFDKTGSTP-----YWIVRNSWGSSWGVDGYAHVKMGSN 308
>gi|23110964 cathepsin W preproprotein [Homo sapiens]
Length = 376
Score = 70.9 bits (172), Expect = 2e-12
Identities = 76/330 (23%), Positives = 126/330 (38%), Gaps = 67/330 (20%)
Query: 162 EQVNKGDYGWTAQNYSQFWGMTLED-----GFKFRLGTLPPSPMLLSMNEMTASLPATTD 216
+++ + D G + F +T E+ G++ G +P + E S+P + D
Sbjct: 74 QRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCD 133
Query: 217 LPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYT----ANLSPQN 272
K G DQKNC WA + A I++ R + ++S Q
Sbjct: 134 WR-------KVAGAISPIKDQKNCNCCWAMAAAG------NIETLWRISFWDFVDVSVQE 180
Query: 273 LISCCAKNRHGCNSGSI-DRAWWYLRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGK 331
L+ C + GC+ G + D L GL S YP G+ +
Sbjct: 181 LLDC-GRCGDGCHGGFVWDAFITVLNNSGLASEKDYPF-----------------QGKVR 222
Query: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGI 391
H P +K ++ + +NE I + + GP+ + ++ Y+ G+
Sbjct: 223 AHRCHP-----KKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKP-LQLYRKGV 276
Query: 392 YRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQG---------------QKEKFWIAAN 436
+ +T +L H+V L G+G+++ +G +WI N
Sbjct: 277 IKATPTTCDP-----QLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKN 331
Query: 437 SWGKSWGENGYFRILRGVNESDIEKLIIAA 466
SWG WGE GYFR+ RG N I K + A
Sbjct: 332 SWGAQWGEKGYFRLHRGSNTCGITKFPLTA 361
>gi|6042196 cathepsin F [Homo sapiens]
Length = 484
Score = 53.9 bits (128), Expect = 3e-07
Identities = 75/327 (22%), Positives = 124/327 (37%), Gaps = 56/327 (17%)
Query: 146 QWKCSQHVC-LVRSELIEQVNKGDYGWTAQ-NYSQFWGMTLEDGFKFRLGTL---PPSPM 200
+W+ S V +VR++ I+ +++G TAQ ++F +T E+ L TL P
Sbjct: 205 RWRLSVFVNNMVRAQKIQALDRG----TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGNK 260
Query: 201 LLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFS-TASVAADRIAIQ 259
+ + P D ++ G DQ C + WAFS T +V Q
Sbjct: 261 MKQAKSVGDLAPPEWD--------WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
Query: 260 SKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNG 319
+LS Q L+ C ++ C G A+ ++ G
Sbjct: 313 GT---LLSLSEQELLDCDKMDK-ACMGGLPSNAYSAIKNLG------------------- 349
Query: 320 CAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQ 379
+ + D + H + C + EK+ ++Y + +S NE ++ + + GP+ +
Sbjct: 350 -GLETEDDYSYQGHM-QSCNFSAEKA-KVY-INDSVELSQNEQKLAAWLAKRGPISVAIN 405
Query: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439
+ YRH S L HAV L G+G FW NSWG
Sbjct: 406 A------FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVP-----FWAIKNSWG 454
Query: 440 KSWGENGYFRILRGVNESDIEKLIIAA 466
WGE GY+ + RG + + +A
Sbjct: 455 TDWGEKGYYYLHRGSGACGVNTMASSA 481
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 25/98 (25%)
Query: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWY 116
C C D + CV Y N L + D C CP
Sbjct: 365 CHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE--CP-------------------- 402
Query: 117 PEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G Y GSV+KE+CN+CTC+ +W+CS VC
Sbjct: 403 ---CEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 30.4 bits (67), Expect = 3.7
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G + C++C C ++C+ H C
Sbjct: 875 CTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 25/98 (25%)
Query: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWY 116
C C D + CV Y N L + D C CP
Sbjct: 437 CHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE--CP-------------------- 474
Query: 117 PEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G Y GSV+KE+CN+CTC+ +W+CS VC
Sbjct: 475 ---CEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 30.4 bits (67), Expect = 3.7
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G + C++C C ++C+ H C
Sbjct: 947 CTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 25/98 (25%)
Query: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWY 116
C C D + CV Y N L + D C CP
Sbjct: 365 CHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE--CP-------------------- 402
Query: 117 PEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G Y GSV+KE+CN+CTC+ +W+CS VC
Sbjct: 403 ---CEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 30.4 bits (67), Expect = 3.7
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G + C++C C ++C+ H C
Sbjct: 875 CTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 25/98 (25%)
Query: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWY 116
C C D + CV Y N L + D C CP
Sbjct: 437 CHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE--CP-------------------- 474
Query: 117 PEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G Y GSV+KE+CN+CTC+ +W+CS VC
Sbjct: 475 ---CEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 30.4 bits (67), Expect = 3.7
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G + C++C C ++C+ H C
Sbjct: 947 CTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 25/98 (25%)
Query: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWY 116
C C D + CV Y N L + D C CP
Sbjct: 365 CHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE--CP-------------------- 402
Query: 117 PEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G Y GSV+KE+CN+CTC+ +W+CS VC
Sbjct: 403 ---CEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 30.4 bits (67), Expect = 3.7
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G + C++C C ++C+ H C
Sbjct: 875 CTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 25/98 (25%)
Query: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWY 116
C C D + CV Y N L + D C CP
Sbjct: 437 CHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE--CP-------------------- 474
Query: 117 PEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G Y GSV+KE+CN+CTC+ +W+CS VC
Sbjct: 475 ---CEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 30.4 bits (67), Expect = 3.7
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G + C++C C ++C+ H C
Sbjct: 947 CTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 48.1 bits (113), Expect = 2e-05
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
CF G+ Y G +K CN+C C ++W C+ HVC
Sbjct: 829 CFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
Score = 40.0 bits (92), Expect = 0.005
Identities = 13/35 (37%), Positives = 18/35 (51%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G+ + +CN+C C QW CS C
Sbjct: 350 CVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEEC 384
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 43.5 bits (101), Expect = 4e-04
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 19/93 (20%)
Query: 63 CEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGCFK 122
C D GC + + +C D C E++ P C
Sbjct: 1478 CHTLDVGCFSTHCVSGCVCPPGLVSDGSGG---------CIAEEDCP----------CVH 1518
Query: 123 DGQHYEEGSVIKENCNSCTCSGQQWKCSQHVCL 155
+ Y+ G I+ +CN+CTC ++W+CS +CL
Sbjct: 1519 NEATYKPGETIRVDCNTCTCRNRRWECSHRLCL 1551
Score = 40.0 bits (92), Expect = 0.005
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 73 EFYAANALCYCDKFCDRENSDCCPDY---KSFCREEKEWPPHTQ----PWYPEGCFKDGQ 125
+++ + C D ++E+S C D+ FC E Q P C +G
Sbjct: 343 QYHECRSPC-ADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGA 401
Query: 126 HYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
Y G+ +C +CTCSG +W C + C
Sbjct: 402 AYAPGATYSTDCTNCTCSGGRWSCQEVPC 430
Score = 38.5 bits (88), Expect = 0.013
Identities = 14/35 (40%), Positives = 18/35 (51%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y G+ C+SCTCSG W+C C
Sbjct: 1046 CTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPC 1080
Score = 38.1 bits (87), Expect = 0.018
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 15/94 (15%)
Query: 69 GCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPE---------G 119
GC + A C K C + C D + PP +QP++ E G
Sbjct: 1856 GCEWHYQPCGAPCL--KTCRNPSGHCLVDLPGLEGCYPKCPP-SQPFFNEDQMKCVAQCG 1912
Query: 120 CF-KDGQHYEEGSVIK--ENCNSCTCSGQQWKCS 150
C+ KDG +Y+ G+ + ENC SC C+ +C+
Sbjct: 1913 CYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCA 1946
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 17/61 (27%)
Query: 84 DKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGCFKDGQHYEEGSVIKE--NCNSCT 141
+ C +E DCCP ++ CR P+ C +G Y G+ C+ CT
Sbjct: 5839 ESICTQEEGDCCPTFR--CR-------------PQLCSYNGTFYGVGATFPGALPCHMCT 5883
Query: 142 C 142
C
Sbjct: 5884 C 5884
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 10/58 (17%)
Query: 97 DYKSFCREEKEWPPHTQPWYPEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
D + C EKE P C + Y G+ IK +CN+CTC +W C+Q VC
Sbjct: 809 DGRGGCVVEKECP----------CVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 856
Score = 31.2 bits (69), Expect = 2.2
Identities = 23/96 (23%), Positives = 31/96 (32%), Gaps = 32/96 (33%)
Query: 62 CCEDRDDGCVTEFYAANALCYCDK---FCDRENSDCCPDYKSFCREEKEWPPHTQPWYPE 118
C E R DGC +C + + D +S C P + CR
Sbjct: 321 CEEHRMDGC-----------FCPEGTVYDDIGDSGCVPVSQCHCRLH------------- 356
Query: 119 GCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
G Y G I +C C C+ +W C C
Sbjct: 357 -----GHLYTPGQEITNDCEQCVCNAGRWVCKDLPC 387
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 43.5 bits (101), Expect = 4e-04
Identities = 16/35 (45%), Positives = 20/35 (57%)
Query: 120 CFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
C G+ Y+EGSV CN CTC W C+Q+ C
Sbjct: 1279 CSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 33.1 bits (74), Expect = 0.57
Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 120 CFKDGQHYEEGSVIKENCNS-CTCSGQQWKCSQHVC 154
C G Y+ G V + C S CTC +W C++ +C
Sbjct: 819 CESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALC 854
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 10/58 (17%)
Query: 97 DYKSFCREEKEWPPHTQPWYPEGCFKDGQHYEEGSVIKENCNSCTCSGQQWKCSQHVC 154
D + C EKE P C + Y G+ IK +CN+CTC +W C+Q VC
Sbjct: 710 DGRGGCVVEKECP----------CVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 757
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,622,658
Number of Sequences: 37866
Number of extensions: 910356
Number of successful extensions: 2255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2044
Number of HSP's gapped (non-prelim): 192
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.