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Search of human proteins with 223890259
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890259 midline 2 isoform 2 [Homo sapiens]
(705 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890259 midline 2 isoform 2 [Homo sapiens] 1445 0.0
gi|223890257 midline 2 isoform 1 [Homo sapiens] 1429 0.0
gi|148833499 midline 1 [Homo sapiens] 1090 0.0
gi|4557753 midline 1 [Homo sapiens] 1090 0.0
gi|15451852 midline 1 [Homo sapiens] 1090 0.0
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 217 3e-56
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 205 1e-52
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 203 4e-52
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 202 1e-51
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 199 7e-51
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 199 7e-51
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 197 4e-50
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 163 4e-40
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 144 4e-34
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 125 1e-28
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 124 3e-28
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 124 3e-28
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 124 3e-28
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 123 7e-28
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 113 7e-25
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 108 2e-23
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 105 1e-22
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 103 4e-22
gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens] 89 1e-17
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam... 89 2e-17
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet... 89 2e-17
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph... 89 2e-17
gi|48255913 tripartite motif-containing 16 [Homo sapiens] 84 4e-16
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 82 2e-15
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 82 2e-15
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 1445 bits (3740), Expect = 0.0
Identities = 705/705 (100%), Positives = 705/705 (100%)
Query: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS
Sbjct: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
Query: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES
Sbjct: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
Query: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR
Sbjct: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
Query: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK
Sbjct: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
Query: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI
Sbjct: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
Query: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA
Sbjct: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
Query: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT
Sbjct: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
Query: 421 VHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI 480
VHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI
Sbjct: 421 VHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI 480
Query: 481 FIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPE 540
FIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPE
Sbjct: 481 FIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPE 540
Query: 541 RFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRC 600
RFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRC
Sbjct: 541 RFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRC 600
Query: 601 NSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPT 660
NSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPT
Sbjct: 601 NSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPT 660
Query: 661 FTIWNKSLMILSGLPAPDFIDYPERQECNCRPQESPYVSGMKTCH 705
FTIWNKSLMILSGLPAPDFIDYPERQECNCRPQESPYVSGMKTCH
Sbjct: 661 FTIWNKSLMILSGLPAPDFIDYPERQECNCRPQESPYVSGMKTCH 705
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 1429 bits (3699), Expect = 0.0
Identities = 705/735 (95%), Positives = 705/735 (95%), Gaps = 30/735 (4%)
Query: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS
Sbjct: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
Query: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES
Sbjct: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
Query: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR
Sbjct: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
Query: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK
Sbjct: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
Query: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI
Sbjct: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
Query: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA
Sbjct: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
Query: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT
Sbjct: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
Query: 421 VHWISDDEFSISSYELQYTIFTGQANFIS------------------------------L 450
VHWISDDEFSISSYELQYTIFTGQANFIS L
Sbjct: 421 VHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGL 480
Query: 451 YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP 510
YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP
Sbjct: 481 YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP 540
Query: 511 KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS 570
KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS
Sbjct: 541 KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS 600
Query: 571 TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY 630
TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY
Sbjct: 601 TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY 660
Query: 631 DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC 690
DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC
Sbjct: 661 DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC 720
Query: 691 RPQESPYVSGMKTCH 705
RPQESPYVSGMKTCH
Sbjct: 721 RPQESPYVSGMKTCH 735
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 1090 bits (2819), Expect = 0.0
Identities = 507/665 (76%), Positives = 590/665 (88%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
Query: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
+VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER + T S+E++ CQ
Sbjct: 61 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
Query: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200
FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+AKLIQ CQ VEVN + EAKL EECD L+EIIQQR+Q+I KIKE KVM+LRKLAQQ+A
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380
NC+QC+ERS LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
Query: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440
FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
Query: 441 FTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLK 500
FTGQAN +SL NS DSWMIVPNIKQNHYTVHGLQSGT+YIF+VKAINQAGSR+SEP +LK
Sbjct: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
Query: 501 TNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGC 560
TNSQPFKLDPK H+KLK+S+D L +E+DESS KKSHTPERF+ G YG AGN+FIDSG
Sbjct: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
Query: 561 HYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPH 620
HYWEVV+ STWYAIG+AYKSAPK+EWIGKN++SW RCN+N+VVRHN+KE+ ++ PH
Sbjct: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
Query: 621 LKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFI 680
L+R+G+LLDYDN ++FYD NS+HL+TFDV F PVCPTFT+WNK L I++GLP PD +
Sbjct: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
Query: 681 DYPER 685
D E+
Sbjct: 661 DCTEQ 665
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 1090 bits (2819), Expect = 0.0
Identities = 507/665 (76%), Positives = 590/665 (88%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
Query: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
+VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER + T S+E++ CQ
Sbjct: 61 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
Query: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200
FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+AKLIQ CQ VEVN + EAKL EECD L+EIIQQR+Q+I KIKE KVM+LRKLAQQ+A
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380
NC+QC+ERS LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
Query: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440
FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
Query: 441 FTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLK 500
FTGQAN +SL NS DSWMIVPNIKQNHYTVHGLQSGT+YIF+VKAINQAGSR+SEP +LK
Sbjct: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
Query: 501 TNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGC 560
TNSQPFKLDPK H+KLK+S+D L +E+DESS KKSHTPERF+ G YG AGN+FIDSG
Sbjct: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
Query: 561 HYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPH 620
HYWEVV+ STWYAIG+AYKSAPK+EWIGKN++SW RCN+N+VVRHN+KE+ ++ PH
Sbjct: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
Query: 621 LKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFI 680
L+R+G+LLDYDN ++FYD NS+HL+TFDV F PVCPTFT+WNK L I++GLP PD +
Sbjct: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
Query: 681 DYPER 685
D E+
Sbjct: 661 DCTEQ 665
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 1090 bits (2819), Expect = 0.0
Identities = 507/665 (76%), Positives = 590/665 (88%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
Query: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
+VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER + T S+E++ CQ
Sbjct: 61 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
Query: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200
FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+AKLIQ CQ VEVN + EAKL EECD L+EIIQQR+Q+I KIKE KVM+LRKLAQQ+A
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380
NC+QC+ERS LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
Query: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440
FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
Query: 441 FTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLK 500
FTGQAN +SL NS DSWMIVPNIKQNHYTVHGLQSGT+YIF+VKAINQAGSR+SEP +LK
Sbjct: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
Query: 501 TNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGC 560
TNSQPFKLDPK H+KLK+S+D L +E+DESS KKSHTPERF+ G YG AGN+FIDSG
Sbjct: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
Query: 561 HYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPH 620
HYWEVV+ STWYAIG+AYKSAPK+EWIGKN++SW RCN+N+VVRHN+KE+ ++ PH
Sbjct: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
Query: 621 LKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFI 680
L+R+G+LLDYDN ++FYD NS+HL+TFDV F PVCPTFT+WNK L I++GLP PD +
Sbjct: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
Query: 681 DYPER 685
D E+
Sbjct: 661 DCTEQ 665
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 217 bits (553), Expect = 3e-56
Identities = 162/616 (26%), Positives = 284/616 (46%), Gaps = 86/616 (13%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRIL---------VSSCSSGESIEPI 71
++ +E EL CP C ELF PL+LPC HS+C C +L V S +S +S +
Sbjct: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
Query: 72 ---------------------------TAFQCPTCRYVISLNHRGLDGLKRNVTLQNIID 104
T F CP C + + L RG++GL RN TL+ I++
Sbjct: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
Query: 105 RFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDR 164
R+++A+ R TA I C C+ PP+++ K+C+ C SYC+
Sbjct: 144 RYRQAA----------------RAATA-----IMCDLCKP-PPQESTKSCMDCSASYCNE 181
Query: 165 CLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRH 224
C + HP H V P + + + C +HE E++NMYC + +C LCKL G H
Sbjct: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
Query: 225 RDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLME 284
+H+V +++ ++ LK+ L ++ L+ + S++++Q+++L + ++ E N + + +
Sbjct: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
Query: 285 ECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKEND 344
++L E++++RK + I +K ++L K Q+ + LE + L+ A+ +LKE D
Sbjct: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNG-LVGYAQEVLKETD 360
Query: 345 QARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAP-N 403
Q+ F+Q+AK + R+ AT S + P +FE++ ++ S++ +LL L + ++ +
Sbjct: 361 QSCFVQTAKQLHLRIQKATESLKSFRPAA--QTSFEDYVVNTSKQTELLGELSFFSSGID 418
Query: 404 PPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNI 463
P I EE ++ + ++W ++ SY L+Y SW + +
Sbjct: 419 VPEINEEQSKVYNNAL-INWHHPEKDKADSYVLEYRKINRDDEM--------SWNEI-EV 468
Query: 464 KQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTR---LKTNSQP---FKLDPKM----T 513
+ L++ + Y F V+A GS S +R L T P F D K
Sbjct: 469 CGTSKIIQDLENSSTYAFRVRAYK--GSICSPCSRELILHTPPAPVFSFLFDEKCGYNNE 526
Query: 514 HKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEV-VMGSSTW 572
H L + D ++ + L + + T G+ I G H+W V S
Sbjct: 527 HLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYL 586
Query: 573 YAIGIAYKSAPKNEWI 588
+G+A S EW+
Sbjct: 587 VKVGVA-SSDKLQEWL 601
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 205 bits (522), Expect = 1e-52
Identities = 176/742 (23%), Positives = 306/742 (41%), Gaps = 132/742 (17%)
Query: 18 SLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEP------- 70
S M+ +E EL CP+C E+++ PL+LPC H++C +CA +L G +P
Sbjct: 21 STSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSP 80
Query: 71 --------------------------------------------ITAFQCPTCRYVISLN 86
+ F CP C+ + L
Sbjct: 81 ASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELG 140
Query: 87 HRGLDGLKRNVTLQNIIDRF-QKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQD 145
RGL GL RN+TL+ +++R+ Q SV G I CQ C+
Sbjct: 141 ERGLAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLCKP- 177
Query: 146 PPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNM 205
PP +A K C C ++C+ C + HP H P +G+ C DH+ E+V
Sbjct: 178 PPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHK-EEVTH 236
Query: 206 YCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLI 265
YC + +L+C LC++ H H++ + ++ LK L +LT ++ ++ Q+ +L
Sbjct: 237 YCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELE 296
Query: 266 QICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQC 325
+ + EV+ + ++ + L ++++++ + I+E + +L +L+ Q+ R
Sbjct: 297 EAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSL 356
Query: 326 LERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALD 385
L+ S L+ A+ +LKE DQ F+Q+AK + R+A AT + Q P + +F + LD
Sbjct: 357 LDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAA--SSSFRHCQLD 413
Query: 386 FSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQA 445
RE KLL L++L P P I + T ++D I + W S YT+ +
Sbjct: 414 VGREMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCWRLPPH---SPPAWHYTVEFRRT 469
Query: 446 NFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQ 504
+ + W ++ + +G+ Y+ V+ N+AG SE L T
Sbjct: 470 D-VPAQPGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPA 528
Query: 505 P---FKLDPK--MTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAA----GNIF 555
P F LD + + ++L IS D + + L +R TGC+ + G++
Sbjct: 529 PVLHFFLDSRWGASRERLAISKD-QRAVRSVPGLPLLLAADRLL-TGCHLSVDVVLGDVA 586
Query: 556 IDSGCHYWEVVMGSSTWYA-IGIAYKSAPKNEWIG------------------------K 590
+ G YW + +++ +G+ +S + + G +
Sbjct: 587 VTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVE 646
Query: 591 NASSWVF-----------SRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYD 639
+ + F S +SN + + P RLG+ LDY+ +SF D
Sbjct: 647 ASPPFAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLD 706
Query: 640 PANSLHLHTFDVTFILPVCPTF 661
+ L + PVCP F
Sbjct: 707 AVSFRGLLECPLDCSGPVCPAF 728
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 203 bits (517), Expect = 4e-52
Identities = 142/486 (29%), Positives = 242/486 (49%), Gaps = 46/486 (9%)
Query: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299
K+ L+ ++ L +N E++N + L + V+ N++ ++L EE D L I+ + K+
Sbjct: 5 KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
Query: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
+ IK+ + K ++L Q++ C LE S L+ A L + F ++A+ I +RV
Sbjct: 65 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
Query: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419
MA+A L P ++ D + +DFS+E+++L+ L +L P P I C + +++
Sbjct: 125 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 182
Query: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISLYNSVDS--WMIVPNIKQNHYTVHGLQSG 476
TV W + +++ I + L++ + NF L D W I+ NIK YT+ GL+
Sbjct: 183 TVAWRMPEEDNKIDHFILEHR----KTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFD 238
Query: 477 TRYI-FIVKAINQA-GSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEK-----D 529
++Y+ F V+A N+A S+P L+T + F LD +H LK+ + ++ +
Sbjct: 239 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQ 298
Query: 530 ESSLK------KSHTP------------------ERFSGTGCYGAAGNIFIDSGCHYWEV 565
ES +K +S TP +RF+G Y G+ I+SG HYWEV
Sbjct: 299 ESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGES-YTVLGDTAIESGQHYWEV 357
Query: 566 -VMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCN---SNFVVRHNNKEMLVDVPPHL 621
Y++G+AYK+ K + +GK +SW N + F +HNNK +DV
Sbjct: 358 KAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVP- 416
Query: 622 KRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFID 681
+++GV D+D LSFYD + L++F F PV P F +W L + +G+ P +
Sbjct: 417 EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVR 476
Query: 682 YPERQE 687
++ E
Sbjct: 477 TLQKSE 482
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 202 bits (513), Expect = 1e-51
Identities = 141/486 (29%), Positives = 242/486 (49%), Gaps = 46/486 (9%)
Query: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299
++ L+ ++ L +N E++N + L + V+ N++ ++L EE D L I+ + K+
Sbjct: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
Query: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
+ IK+ + K ++L Q++ C LE S L+ A L + F ++A+ I +RV
Sbjct: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
Query: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419
MA+A L P ++ D + +DFS+E+++L+ L +L P P I C + +++
Sbjct: 157 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
Query: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISLYNSVDS--WMIVPNIKQNHYTVHGLQSG 476
TV W + +++ I + L++ + NF L D W I+ NIK YT+ GL+
Sbjct: 215 TVAWRMPEEDNKIDHFILEHR----KTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFD 270
Query: 477 TRYI-FIVKAINQA-GSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEK-----D 529
++Y+ F V+A N+A S+P L+T + F LD +H LK+ + ++ +
Sbjct: 271 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQ 330
Query: 530 ESSLK------KSHTP------------------ERFSGTGCYGAAGNIFIDSGCHYWEV 565
ES +K +S TP +RF+G Y G+ I+SG HYWEV
Sbjct: 331 ESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGES-YTVLGDTAIESGQHYWEV 389
Query: 566 -VMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCN---SNFVVRHNNKEMLVDVPPHL 621
Y++G+AYK+ K + +GK +SW N + F +HNNK +DV
Sbjct: 390 KAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVP- 448
Query: 622 KRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFID 681
+++GV D+D LSFYD + L++F F PV P F +W L + +G+ P +
Sbjct: 449 EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVR 508
Query: 682 YPERQE 687
++ E
Sbjct: 509 TLQKSE 514
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 199 bits (506), Expect = 7e-51
Identities = 144/484 (29%), Positives = 234/484 (48%), Gaps = 47/484 (9%)
Query: 237 EKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQR 296
E+ ++ L + L +N E+++ + L Q+ VE N+A + L E L ++++
Sbjct: 2 EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
Query: 297 KQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIA 356
K+ + +KIK+ + + +L Q+A C + LE S L+ A L+ D F Q+AK I
Sbjct: 62 KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
Query: 357 ERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH 416
+ V MA A L + +D + +DF++E+++L+ L +L P+ P I +
Sbjct: 122 DGVTMAPAFRLSLKAKV--SDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
Query: 417 DTITVHW-ISDDEFSISSYELQY--TIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGL 473
+ +T+ W + D++ I Y L+Y T F G WM++ I+Q YT+ GL
Sbjct: 180 NCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRL----KEDQPWMVIEGIRQTEYTLTGL 235
Query: 474 QSGTRYI-FIVKAINQA-GSRNSEPTRLKTNSQPFKLDPKMTHKKLKISN---------- 521
+ +Y+ F VKA N+A SEP L+T + F+LD +H+ L++ +
Sbjct: 236 KFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGG 295
Query: 522 ---DGLQMEKD---------ESSLKKSHTPERF-SGTG--------CYGAAGNIFIDSGC 560
D EKD S + + +P+R SG G Y G+ ID G
Sbjct: 296 KVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGE 355
Query: 561 HYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKNASSW---VFSRCNSNFVVRHNNKEMLVD 616
HYWEV S + +G+AY+S + E +GK A+SW V + +F +H NK ++D
Sbjct: 356 HYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLD 415
Query: 617 VPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPA 676
P LGV D+ +LSFY+ LHTF F P+ P FT+W S + +GL
Sbjct: 416 APVP-DCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQV 474
Query: 677 PDFI 680
P +
Sbjct: 475 PSAV 478
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 199 bits (506), Expect = 7e-51
Identities = 165/641 (25%), Positives = 273/641 (42%), Gaps = 114/641 (17%)
Query: 60 SSCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE 119
++CSS S ++ CP C SL+HRGL G +RN L+ I+ R+Q+
Sbjct: 145 AACSSLSSSS--SSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQG---------- 192
Query: 120 SRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSH 179
R P T+ ++ CQ C++ PP A C C+V YC C HP++ PF H
Sbjct: 193 ----RGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKH 248
Query: 180 RLVEPVP---------------------------------------DTHLRGITCLDHEN 200
RLV+P P T + TC +HE
Sbjct: 249 RLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEM 308
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
E +MYCVS +C LC GRH H+V L +++ K L L + + E +
Sbjct: 309 ENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEF 368
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+ +L I QQ++ N +EA L+ +CD LV+ + ++K + K+ + + KL+ + Q+
Sbjct: 369 LVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQIN 428
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATAS--SQVLIPDINFNDA 378
+C L +ST L+ ++KEND + FLQ + + +RV ++ L P ++ A
Sbjct: 429 HCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVS---A 485
Query: 379 FENFALDFSREKKLLEGLDYL----TAPNPPSIREELCTASHDTITVHWISD--DEFSIS 432
+ LD + + LD++ P P ++ E C ++++T+ W +
Sbjct: 486 EFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVD 545
Query: 433 SYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-S 491
Y L+ G F +Y K+ T+ GL + Y VKA N +G
Sbjct: 546 GYILELDDGAG-GQFREVYVG----------KETLCTIDGLHFNSTYNARVKAFNSSGVG 594
Query: 492 RNSEPTRLKTNSQP-FKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGA 550
S+ L+T+ F DP H+ + +SND ++++ S+ GT +
Sbjct: 595 PYSKTVVLQTSDVAWFTFDPNSGHRDIILSND------NQTATCSSYDDRVVLGTAAF-- 646
Query: 551 AGNIFIDSGCHYWEVVMGSSTWY---AIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVR 607
G HYWE+ + + A G+A S K+ +GK+ +W +
Sbjct: 647 ------SKGVHYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWA--------MYV 692
Query: 608 HNNKEMLVDVPPHLKR----------LGVLLDYDNNMLSFY 638
NN+ + H R +GVLLD + + L+F+
Sbjct: 693 DNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFF 733
Score = 51.2 bits (121), Expect = 3e-06
Identities = 18/38 (47%), Positives = 27/38 (71%)
Query: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSS 61
+E EL CP+C LF +P++LPC+H++C CA I V +
Sbjct: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQT 38
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 197 bits (500), Expect = 4e-50
Identities = 163/627 (25%), Positives = 260/627 (41%), Gaps = 75/627 (11%)
Query: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135
CP C + L+ RGL G +N L+ +IDR+Q++ +
Sbjct: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165
Query: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193
+ CQ CE+ P++A C C+V YCD C HP + P HRLV P R +
Sbjct: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
Query: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249
TC DHE E +MYCV +C C G+H H+V +L ++ K L L
Sbjct: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
Query: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309
L R E + + +L + QQ++ N+ EA L+ +CD L++ + +RK + ++ +
Sbjct: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
Query: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367
KL+ + Q+++C L ++T L+ ++KEND + FLQ + + RV +
Sbjct: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
Query: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421
L P + + + +LD S + + LD++ P P ++ E C +++ T+
Sbjct: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
Query: 422 HWISDDEFSI--SSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRY 479
W ++ Y L+ G F +Y K+ TV GL + Y
Sbjct: 461 SWKQPPLSTVPADGYILELDDGNG-GQFREVYVG----------KETMCTVDGLHFNSTY 509
Query: 480 IFIVKAINQAGSRNSEPTRLKTNSQP--FKLDPKMTHKKLKISNDGLQMEKDESSLKKSH 537
VKA N+ G T + S+ F DP H + +SND L +
Sbjct: 510 NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV----------- 558
Query: 538 TPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWY---AIGIAYKSAPKNEWIGKNASS 594
T + G G G HYWE+ + + A G+A K+ +GK+ +
Sbjct: 559 TCSSYDDRVVLGKTG---FSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKA 615
Query: 595 WVFSRCNSNFVVRHNNKEMLVDVPPHLK--RLGVLLDYDNNMLSFYDPANSLHLHTFDVT 652
W N+ HNN K +GVLLD + L+F+ FD
Sbjct: 616 WAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNV 675
Query: 653 FILPVCPTFTIWNKSLMILSGLPAPDF 679
L N + + +GLP PDF
Sbjct: 676 EGLFFPAVSLNRNVQVTLHTGLPVPDF 702
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 163 bits (413), Expect = 4e-40
Identities = 120/459 (26%), Positives = 201/459 (43%), Gaps = 54/459 (11%)
Query: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135
CP C + L+ RGL G +N L+ +IDR+Q++ +
Sbjct: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165
Query: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193
+ CQ CE+ P++A C C+V YCD C HP + P HRLV P R +
Sbjct: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
Query: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249
TC DHE E +MYCV +C C G+H H+V +L ++ K L L
Sbjct: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
Query: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309
L R E + + +L + QQ++ N+ EA L+ +CD L++ + +RK + ++ +
Sbjct: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
Query: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367
KL+ + Q+++C L ++T L+ ++KEND + FLQ + + RV +
Sbjct: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
Query: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421
L P + + + +LD S + + LD++ P P ++ E C +++ T+
Sbjct: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
Query: 422 HWISDDEFSI--SSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRY 479
W ++ Y L+ G F +Y K+ TV GL + Y
Sbjct: 461 SWKQPPLSTVPADGYILELDDGNG-GQFREVYVG----------KETMCTVDGLHFNSTY 509
Query: 480 IFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLK 518
VKA N+ G T + S+ L + ++L+
Sbjct: 510 NARVKAFNKTGVSPYSKTLVLQTSEGKALQQYPSERELR 548
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 144 bits (362), Expect = 4e-34
Identities = 155/659 (23%), Positives = 255/659 (38%), Gaps = 63/659 (9%)
Query: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83
L EL+C ICLE F++P+ PC H+ C SC + S + CP CR V
Sbjct: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS---------PYLCPQCRAV- 56
Query: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
++ L +N L N++++F +A ++ P R + + ++AC C
Sbjct: 57 ---YQARPQLHKNTVLCNVVEQFLQADLA--REPPADVWTPPARASAPSPNAQVACDHCL 111
Query: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
++ AVKTC+ C S+C L+ H + F H L PV D R C H N
Sbjct: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQH-NRLR 164
Query: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263
+C + IC +C + H+ ASL+ L+ TL LT + + + +
Sbjct: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
Query: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323
+ Q V + +L +E E+ ++ + KIKE + K
Sbjct: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILL 282
Query: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN----DAF 379
+ L + E L + D+ FL+ A + ++ V IP++ N
Sbjct: 283 KKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGI 337
Query: 380 ENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH-DTITVHWISDDEFS------IS 432
+D E K G P+ E ++H T V +S +E +
Sbjct: 338 HQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVP 397
Query: 433 SYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSR 492
+ + F + L + +H L++ F+ K
Sbjct: 398 ALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-------- 447
Query: 493 NSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAG 552
S P L+ + LD H K+ +S E P+RF T C G
Sbjct: 448 -SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRF--TYCSQVLG 503
Query: 553 NIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPK---NEWIGKNASSWVFSRCNSNFVVRHN 609
G HYWEV + + + +GI Y S + +G+N++SW N+ HN
Sbjct: 504 LHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHN 563
Query: 610 NKEMLVDVPPHLK--RLGVLLDYDNNMLSFYDPANSLHL-HTFDVTFILPVCPTFTIWN 665
N E + P K R+GVLL+ D+ + F+ A+ +HL + F V F + P F +++
Sbjct: 564 NVEKTL---PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 125 bits (314), Expect = 1e-28
Identities = 97/390 (24%), Positives = 178/390 (45%), Gaps = 48/390 (12%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSSCSSGESIEPITA-----F 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA+ + +S +S T F
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+ E+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR--LVEPVPDTHLR- 191
CE+ C++CEV C C K F +H+ V P+P + R
Sbjct: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
Query: 192 ---GITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLT 248
+T L + C + C+L L +AS N + + L +
Sbjct: 171 KKQDLTLLP------RLECSGTNTTYCSL-DLPSSSDPPILASQNTKI--IDSELSDGIA 221
Query: 249 NLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETK 308
LV N ++ + ++ ++CQ +E N+ + L + + L ++++RK + + +
Sbjct: 222 MLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQ 281
Query: 309 VMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQV 368
KL+++ + LE S+ L+ A ++E A +LQ AK + +V +
Sbjct: 282 EEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELA 341
Query: 369 LIPDINFNDAFENFALDFSREKKLLEGLDY 398
P+ + ++ E F + ++L +D+
Sbjct: 342 GRPEPGY-ESMEQFTVRVEHVAEMLRTIDF 370
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 124 bits (311), Expect = 3e-28
Identities = 92/384 (23%), Positives = 167/384 (43%), Gaps = 80/384 (20%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
F++ K L + LV N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ +++L C+ +E + +L E+ D L I+++RK + I T+ KL
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + LE + L+ + E + A FLQ+AK + ++++ A+ + Q+ +
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHG 303
Query: 375 FNDAFENFALDFSREKKLLEGLDY 398
+ + +F ++ +RE+K++ +D+
Sbjct: 304 YEN-MNHFTVNLNREEKIIREIDF 326
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 124 bits (311), Expect = 3e-28
Identities = 92/384 (23%), Positives = 167/384 (43%), Gaps = 80/384 (20%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
F++ K L + LV N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ +++L C+ +E + +L E+ D L I+++RK + I T+ KL
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + LE + L+ + E + A FLQ+AK + ++++ A+ + Q+ +
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHG 303
Query: 375 FNDAFENFALDFSREKKLLEGLDY 398
+ + +F ++ +RE+K++ +D+
Sbjct: 304 YEN-MNHFTVNLNREEKIIREIDF 326
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 124 bits (311), Expect = 3e-28
Identities = 92/384 (23%), Positives = 167/384 (43%), Gaps = 80/384 (20%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
F++ K L + LV N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ +++L C+ +E + +L E+ D L I+++RK + I T+ KL
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + LE + L+ + E + A FLQ+AK + ++++ A+ + Q+ +
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHG 303
Query: 375 FNDAFENFALDFSREKKLLEGLDY 398
+ + +F ++ +RE+K++ +D+
Sbjct: 304 YEN-MNHFTVNLNREEKIIREIDF 326
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 123 bits (308), Expect = 7e-28
Identities = 87/294 (29%), Positives = 138/294 (46%), Gaps = 19/294 (6%)
Query: 398 YLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSW 457
Y+TAP+PP I+ + + + + + W S + + SY ++ T QA +S
Sbjct: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELT----QAESPEASGVTESV 520
Query: 458 MIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQPFKLDPKMTHKK 516
+ +P + +V LQ G YI V+A+N G S SEP + T F+L+ H
Sbjct: 521 VGIPTCE----SVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576
Query: 517 LKISNDGLQMEKDESSLK-KSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAI 575
L IS DGL + E + +P T C GN+ G HYWEV + Y +
Sbjct: 577 LTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRV 636
Query: 576 GIAYKSAPKNEWIGKNASSWVF------SRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLD 629
G+A+ K E +G N SW SR F+ ++ + VPP K++G+LLD
Sbjct: 637 GVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPP--KKIGILLD 694
Query: 630 YDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKS-LMILSGLPAPDFIDY 682
Y+++ LSF++ S HL+TF V P F++ L + +G+ P + +
Sbjct: 695 YEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHVTF 748
Score = 100 bits (249), Expect = 5e-21
Identities = 79/311 (25%), Positives = 145/311 (46%), Gaps = 11/311 (3%)
Query: 197 DHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSE 256
+ E E +++CV+ I A K+ H++H+V LN+ E K + N+ L K+ E
Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
Query: 257 LENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLA 316
+EN L ++ VE N E +E++E + Q+ + + E K KL L
Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
Query: 317 QQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN 376
Q+ +C + L+ L+ E + E ++ F++ A +A+R+ + + +I+
Sbjct: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Query: 377 DAFENFALDFSREKKLLEGLDYLTAPNPPSIREEL-CTASHDTITVHWISDDEFSISSYE 435
FE+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W + ++ SY+
Sbjct: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
Query: 436 LQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNS 494
L Y + D +K+ + +V L T+Y F V A N+AG S +S
Sbjct: 407 LSYRPVQDSS------PGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSS 460
Query: 495 EPTRLKTNSQP 505
E T P
Sbjct: 461 ERAVYMTAPSP 471
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 113 bits (282), Expect = 7e-25
Identities = 96/396 (24%), Positives = 164/396 (41%), Gaps = 79/396 (19%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS----CSSGESIEPITA-F 74
ME LE +L CPICLE+F P+ +LPC H+LC CA+ I ++ S G S+ F
Sbjct: 14 MENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRF 73
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CPTCR+ + ++ G+ GL+RN+ ++NIID +++ S P
Sbjct: 74 RCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRP-------------------L 114
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
++ + C++ C+TCEV C C K F H+ E
Sbjct: 115 QKGSHPMCKEHEDEKINIYCLTCEVPTCSMC--------KVFGIHKACE----------- 155
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
VA L F+ K L ++ LV N
Sbjct: 156 ----------------------------------VAPLQSVFQGQKTELNNCISMLVAGN 181
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ + +L + + N+ + +L ++ D L I+ ++K + +I + + KL
Sbjct: 182 DRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSF 241
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + ++ L++ST L+ A L E A FL +AK + + + A+ Q+ +
Sbjct: 242 IEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQG 301
Query: 375 FNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREE 410
F + + F LD L +D+ T EE
Sbjct: 302 FEN-MDFFTLDLEHIADALRAIDFGTDEEEEEFIEE 336
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 108 bits (270), Expect = 2e-23
Identities = 97/362 (26%), Positives = 164/362 (45%), Gaps = 60/362 (16%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSSCSSGESIEPITA-----F 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA+ + +S +S T F
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+ E+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR--LVEPVPDTHLR- 191
CE+ C++CEV C C K F +H+ V P+P + R
Sbjct: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
Query: 192 ------GITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEM 245
GI L N++V ++ +C+ + + Q LN RFE L LE
Sbjct: 171 KSELSDGIAMLVAGNDRVQAVITQMEE----VCQTIEDNSRRQKQLLNQRFESLCAVLEE 226
Query: 246 NLTNLV-----KRNSELENQMAKLIQICQQVEVNTAMHEAKL--MEECDELVEIIQQRKQ 298
L+ ++ +L+ + Q +E ++ + E+ + MEE ++ +QQ K+
Sbjct: 227 RKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEE-PQMALYLQQAKE 285
Query: 299 MIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAER 358
+ I + M +LA + + +E+ TV + +L+ D F A E
Sbjct: 286 L----INKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTID---FQPGASGEEEE 338
Query: 359 VA 360
VA
Sbjct: 339 VA 340
Score = 95.5 bits (236), Expect = 1e-19
Identities = 51/206 (24%), Positives = 105/206 (50%), Gaps = 1/206 (0%)
Query: 193 ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVK 252
+ C +HE EK+N+YC+S + C+LCK+ G H+D +VA L +++ K L + LV
Sbjct: 124 LMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVA 183
Query: 253 RNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKL 312
N ++ + ++ ++CQ +E N+ + L + + L ++++RK + + + KL
Sbjct: 184 GNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKL 243
Query: 313 RKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPD 372
+++ + LE S+ L+ A ++E A +LQ AK + +V + P+
Sbjct: 244 QRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPE 303
Query: 373 INFNDAFENFALDFSREKKLLEGLDY 398
+ ++ E F + ++L +D+
Sbjct: 304 PGY-ESMEQFTVRVEHVAEMLRTIDF 328
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 105 bits (263), Expect = 1e-22
Identities = 87/380 (22%), Positives = 159/380 (41%), Gaps = 48/380 (12%)
Query: 25 ESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGES-IEPITAFQCPTCRYVI 83
E EL CPICL +F +P+ LPC H+ C C GE+ + +CP C
Sbjct: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCI----------GEAWAKDSGLVRCPECNQA- 58
Query: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
+ GL++N+ L NI+++F V P + + C FC
Sbjct: 59 ---YNQKPGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCR 96
Query: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
+ PP A K C+ CE C ++ H LVE +R +C H ++
Sbjct: 97 RGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL 153
Query: 204 NMYCVSDDQLICA-LCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMA 262
+C ++ +C C G H+ H V + R ++++ L L +R ++E+Q+
Sbjct: 154 -YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLY 212
Query: 263 KLIQICQQVE--VNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
KL + VE VN E +L E +L +++ + + + + + + A Q
Sbjct: 213 KLESDKRLVEEKVNQLKEEVRLQYE--KLHQLLDEDLRQTVEVLDKAQAKFCSENAAQAL 270
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNI---AERVAMATAS--SQVLIPDINF 375
+ + ++ + L+ + + + + F+++ K++ +R T+S S I +N
Sbjct: 271 HLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNS 330
Query: 376 NDAFENFALDFSREKKLLEG 395
A + +K+LEG
Sbjct: 331 KLFLNEVAKKEKQLRKMLEG 350
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 103 bits (258), Expect = 4e-22
Identities = 95/411 (23%), Positives = 167/411 (40%), Gaps = 37/411 (9%)
Query: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83
L + L CP+C L +LPC HSLC C ++ E E CP C
Sbjct: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQ----KHAEVTENFFILICPVCDRSH 195
Query: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
+ + L N + R+ + + + R +R SS I CQ C
Sbjct: 196 CMPYSNKMQLPENYLHGRLTKRYMQ-----EHGYLKWRFDR--------SSGPILCQVCR 242
Query: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
R A K CITC ++ C+ CL+A H + H V+ + I C+ H + ++
Sbjct: 243 N--RRIAYKRCITCRLNLCNDCLKAFH-SDVAMQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
Query: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263
YC +D++L+C CK H H SL D + +L + E++N + +
Sbjct: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
Query: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323
+ + + ++ +L I+Q+++++I +I+ +V + +++ + V
Sbjct: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
Query: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFA 383
+ LI ++ LKE Q FLQSAK + +++ ++ P + + +
Sbjct: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
Query: 384 LDF------------SREKKLLEGLDYLTAPNPPSIREELCTASHDTITVH 422
LDF + KK+ D L +P P + E A T + H
Sbjct: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 421 VHWISDDEFSISSYELQ-YTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRY 479
V+W E + S+E++ Y + T N + + + + +I Q + +H L T Y
Sbjct: 621 VYWTCPAE-DVDSFEMEFYEVITSPPNNVQM----ELCGQIRDIMQQNLELHNLTPNTEY 675
Query: 480 IFIVKAINQAG 490
+F V+AIN G
Sbjct: 676 VFKVRAINDNG 686
>gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]
Length = 241
Score = 89.0 bits (219), Expect = 1e-17
Identities = 55/176 (31%), Positives = 85/176 (48%), Gaps = 34/176 (19%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHL 190
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV 164
>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
[Homo sapiens]
Length = 546
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/255 (24%), Positives = 110/255 (43%), Gaps = 34/255 (13%)
Query: 28 LTCPICLELF-----EDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYV 82
L C +C ++F + P LL C H++C C R+ + A +CP R V
Sbjct: 29 LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78
Query: 83 ISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFC 142
L G+ GLK+N L +++R Q + + ES +S E I C
Sbjct: 79 TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESII--RC 127
Query: 143 EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEK 202
++D A C C C C + TH + K HR V P+ D C H+
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185
Query: 203 VNMYCVSD----DQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKR-NSEL 257
+ C+ + L+C +CK G+H+ H+ + L +++ ++ +++ + ++ E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244
Query: 258 ENQMAKLIQICQQVE 272
+ KL+ I Q +E
Sbjct: 245 SDYSRKLVGIVQHIE 259
>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
[Homo sapiens]
Length = 569
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/255 (24%), Positives = 110/255 (43%), Gaps = 34/255 (13%)
Query: 28 LTCPICLELF-----EDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYV 82
L C +C ++F + P LL C H++C C R+ + A +CP R V
Sbjct: 29 LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78
Query: 83 ISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFC 142
L G+ GLK+N L +++R Q + + ES +S E I C
Sbjct: 79 TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESII--RC 127
Query: 143 EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEK 202
++D A C C C C + TH + K HR V P+ D C H+
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185
Query: 203 VNMYCVSD----DQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKR-NSEL 257
+ C+ + L+C +CK G+H+ H+ + L +++ ++ +++ + ++ E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244
Query: 258 ENQMAKLIQICQQVE 272
+ KL+ I Q +E
Sbjct: 245 SDYSRKLVGIVQHIE 259
>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
[Homo sapiens]
Length = 574
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/255 (24%), Positives = 110/255 (43%), Gaps = 34/255 (13%)
Query: 28 LTCPICLELF-----EDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYV 82
L C +C ++F + P LL C H++C C R+ + A +CP R V
Sbjct: 29 LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78
Query: 83 ISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFC 142
L G+ GLK+N L +++R Q + + ES +S E I C
Sbjct: 79 TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESII--RC 127
Query: 143 EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEK 202
++D A C C C C + TH + K HR V P+ D C H+
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185
Query: 203 VNMYCVSD----DQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKR-NSEL 257
+ C+ + L+C +CK G+H+ H+ + L +++ ++ +++ + ++ E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244
Query: 258 ENQMAKLIQICQQVE 272
+ KL+ I Q +E
Sbjct: 245 SDYSRKLVGIVQHIE 259
>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
Length = 564
Score = 84.0 bits (206), Expect = 4e-16
Identities = 125/550 (22%), Positives = 214/550 (38%), Gaps = 93/550 (16%)
Query: 131 AMSSERIACQFCEQDPPR-DAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTH 189
A + + C FC D R AVK+C+TC V+YC+ L+ N K SH L EPV D +
Sbjct: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHN 127
Query: 190 LRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249
R C H + ++ +C D Q IC C H H + SL +
Sbjct: 128 WR--YCPAH-HSPLSAFCCPDQQCICQDC--CQEHSGHTIVSL----------------D 166
Query: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309
+R+ E E Q C Q+++ + KL E + +Q ++ + V + E K
Sbjct: 167 AARRDKEAELQ-------CTQLDLE---RKLKLNENA---ISRLQANQKSVLVSVSEVKA 213
Query: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVL 369
+ + + +A R+ ++ V++ L+E +QA L A I + +A +
Sbjct: 214 VAEMQFGELLAAVRKA--QANVML-----FLEEKEQAA-LSQANGIKAHLEYRSAEMEKS 265
Query: 370 IPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI---TVHWISD 426
++ A N + F E + + +T P+ ++ + I TVH I
Sbjct: 266 KQELERMAAISN-TVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQ- 323
Query: 427 DEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAI 486
+ +Y+ + F+ + + D V + Q Y + TR F+ A
Sbjct: 324 ---LLENYKKKLQEFSKEEEY-------DIRTQVSAVVQRKYWTSKPEPSTREQFLQYAY 373
Query: 487 NQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSH----TPERF 542
+ DP HK L++ + K ++ H P RF
Sbjct: 374 D------------------ITFDPDTAHKYLRLQEEN---RKVTNTTPWEHPYPDLPSRF 412
Query: 543 SGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAI---GIAYKSAPKNEWIGKNASSWVFS 598
+ ++++ +Y+EV + G+ T+ + GI K +N I N SW
Sbjct: 413 LHWRQVLSQQSLYLHR--YYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQ 470
Query: 599 RCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFY--DPANSLHLHTFDVTFILP 656
F +++ E + P +RLGV +D+ +LSFY + +H F F P
Sbjct: 471 WNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEP 529
Query: 657 VCPTFTIWNK 666
V F + K
Sbjct: 530 VYAAFWLSKK 539
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 82.0 bits (201), Expect = 2e-15
Identities = 89/360 (24%), Positives = 148/360 (41%), Gaps = 72/360 (20%)
Query: 29 TCPICLELFE-----DPLLLPCAHSLCFSCAHR------ILVSSCSSGESIEPITAFQCP 77
TC +C + + +P LLPC HS C C + + S+G+ I+ + +CP
Sbjct: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGD-IQQVGVIRCP 182
Query: 78 TCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERI 137
CR R + L + + F K + P+S E SE++
Sbjct: 183 VCRQEC-----------RQIDL--VDNYFVKDTSEAPSSSDEK-------------SEQV 216
Query: 138 ACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLV-------EPVPDTHL 190
C CE + AV C+ C C C+ A H K FT L+ E V +
Sbjct: 217 -CTSCEDNA--SAVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQ 271
Query: 191 RGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNL 250
R + C H+ E++ ++C + D+L C C+L+ H++H+ L + F+ K
Sbjct: 272 RPVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK---------- 320
Query: 251 VKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVM 310
+EN +AKL++ V + ++ E + + Q+ K I I E
Sbjct: 321 ----GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-K 375
Query: 311 KLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLI 370
K + L QQ+ N + ER L+ Q I + Q + + + N A+A+ SS L+
Sbjct: 376 KGKSLLQQLENVTK--ERQMKLLQQQNDITGLSRQVKHVMNFTN----WAIASGSSTALL 429
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 82.0 bits (201), Expect = 2e-15
Identities = 89/360 (24%), Positives = 148/360 (41%), Gaps = 72/360 (20%)
Query: 29 TCPICLELFE-----DPLLLPCAHSLCFSCAHR------ILVSSCSSGESIEPITAFQCP 77
TC +C + + +P LLPC HS C C + + S+G+ I+ + +CP
Sbjct: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGD-IQQVGVIRCP 182
Query: 78 TCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERI 137
CR R + L + + F K + P+S E SE++
Sbjct: 183 VCRQEC-----------RQIDL--VDNYFVKDTSEAPSSSDEK-------------SEQV 216
Query: 138 ACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLV-------EPVPDTHL 190
C CE + AV C+ C C C+ A H K FT L+ E V +
Sbjct: 217 -CTSCEDNA--SAVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQ 271
Query: 191 RGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNL 250
R + C H+ E++ ++C + D+L C C+L+ H++H+ L + F+ K
Sbjct: 272 RPVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK---------- 320
Query: 251 VKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVM 310
+EN +AKL++ V + ++ E + + Q+ K I I E
Sbjct: 321 ----GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-K 375
Query: 311 KLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLI 370
K + L QQ+ N + ER L+ Q I + Q + + + N A+A+ SS L+
Sbjct: 376 KGKSLLQQLENVTK--ERQMKLLQQQNDITGLSRQVKHVMNFTN----WAIASGSSTALL 429
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,638,106
Number of Sequences: 37866
Number of extensions: 1239059
Number of successful extensions: 5073
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 3841
Number of HSP's gapped (non-prelim): 1229
length of query: 705
length of database: 18,247,518
effective HSP length: 109
effective length of query: 596
effective length of database: 14,120,124
effective search space: 8415593904
effective search space used: 8415593904
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.