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Search of human proteins with 223634012
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
(687 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223634012 solute carrier organic anion transporter family, me... 1383 0.0
gi|6005820 solute carrier organic anion transporter family, memb... 1383 0.0
gi|223634014 solute carrier organic anion transporter family, me... 1133 0.0
gi|188528663 solute carrier organic anion transporter family, me... 535 e-152
gi|222831573 solute carrier organic anion transporter family, me... 384 e-106
gi|222831575 solute carrier organic anion transporter family, me... 383 e-106
gi|8394291 solute carrier organic anion transporter family, memb... 352 5e-97
gi|225637473 solute carrier organic anion transporter family, me... 348 7e-96
gi|225543118 solute carrier organic anion transporter family, me... 340 2e-93
gi|9790233 solute carrier organic anion transporter family, memb... 339 4e-93
gi|225543525 solute carrier organic anion transporter family, me... 331 1e-90
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 325 1e-88
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 325 1e-88
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 311 1e-84
gi|225543116 solute carrier organic anion transporter family, me... 300 4e-81
gi|38679890 solute carrier organic anion transporter family, mem... 297 2e-80
gi|39777594 solute carrier organic anion transporter family memb... 290 4e-78
gi|225637477 solute carrier organic anion transporter family, me... 288 1e-77
gi|225543114 solute carrier organic anion transporter family, me... 272 7e-73
gi|93277099 solute carrier organic anion transporter family, mem... 201 2e-51
gi|225637475 solute carrier organic anion transporter family, me... 191 3e-48
gi|186928854 mitochondrial ribosomal protein S31 [Homo sapiens] 33 1.1
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 31 3.3
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 31 3.3
gi|148727298 keratin associated protein 10-6 [Homo sapiens] 31 4.4
gi|4504093 G protein-coupled receptor 32 [Homo sapiens] 30 5.7
gi|26051246 tumor necrosis factor ligand superfamily, member 13 ... 30 7.4
gi|4507599 tumor necrosis factor ligand superfamily, member 13 i... 30 7.4
gi|26051248 tumor necrosis factor ligand superfamily, member 13 ... 30 7.4
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 30 7.4
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 1383 bits (3579), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGL 60
MGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGL
Sbjct: 1 MGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGL 60
Query: 61 SSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPY 120
SSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPY
Sbjct: 61 SSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPY 120
Query: 121 RYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVG 180
RYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVG
Sbjct: 121 RYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVG 180
Query: 181 GVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGG 240
GVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGG
Sbjct: 181 GVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGG 240
Query: 241 ISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPA 300
ISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPA
Sbjct: 241 ISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPA 300
Query: 301 RKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVC 360
RKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVC
Sbjct: 301 RKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVC 360
Query: 361 LSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGC 420
LSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGC
Sbjct: 361 LSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGC 420
Query: 421 GALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNP 480
GALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNP
Sbjct: 421 GALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNP 480
Query: 481 VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVV 540
VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVV
Sbjct: 481 VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVV 540
Query: 541 PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI 600
PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI
Sbjct: 541 PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI 600
Query: 601 DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART 660
DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART
Sbjct: 601 DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART 660
Query: 661 KESRSSPAVEQQLLVSGPGKKPEDSRV 687
KESRSSPAVEQQLLVSGPGKKPEDSRV
Sbjct: 661 KESRSSPAVEQQLLVSGPGKKPEDSRV 687
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 1383 bits (3579), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGL 60
MGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGL
Sbjct: 23 MGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGL 82
Query: 61 SSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPY 120
SSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPY
Sbjct: 83 SSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPY 142
Query: 121 RYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVG 180
RYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVG
Sbjct: 143 RYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVG 202
Query: 181 GVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGG 240
GVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGG
Sbjct: 203 GVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGG 262
Query: 241 ISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPA 300
ISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPA
Sbjct: 263 ISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPA 322
Query: 301 RKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVC 360
RKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVC
Sbjct: 323 RKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVC 382
Query: 361 LSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGC 420
LSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGC
Sbjct: 383 LSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGC 442
Query: 421 GALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNP 480
GALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNP
Sbjct: 443 GALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNP 502
Query: 481 VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVV 540
VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVV
Sbjct: 503 VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVV 562
Query: 541 PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI 600
PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI
Sbjct: 563 PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI 622
Query: 601 DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART 660
DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART
Sbjct: 623 DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART 682
Query: 661 KESRSSPAVEQQLLVSGPGKKPEDSRV 687
KESRSSPAVEQQLLVSGPGKKPEDSRV
Sbjct: 683 KESRSSPAVEQQLLVSGPGKKPEDSRV 709
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 1133 bits (2930), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 128 EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF 187
EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF
Sbjct: 6 EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF 65
Query: 188 GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD 247
GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD
Sbjct: 66 GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD 125
Query: 248 PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP 307
PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP
Sbjct: 126 PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP 185
Query: 308 SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG 367
SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG
Sbjct: 186 SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG 245
Query: 368 MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG 427
MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG
Sbjct: 246 MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG 305
Query: 428 MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR 487
MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR
Sbjct: 306 MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR 365
Query: 488 VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS 547
VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS
Sbjct: 366 VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS 425
Query: 548 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 607
LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW
Sbjct: 426 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 485
Query: 608 ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP 667
ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP
Sbjct: 486 ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP 545
Query: 668 AVEQQLLVSGPGKKPEDSRV 687
AVEQQLLVSGPGKKPEDSRV
Sbjct: 546 AVEQQLLVSGPGKKPEDSRV 565
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 535 bits (1379), Expect = e-152
Identities = 280/646 (43%), Positives = 403/646 (62%), Gaps = 70/646 (10%)
Query: 21 SVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
SVF NIK+FVLC LLQL QL+ S Y KSS++T+EKRFGLSS +SGL++S NE+ N LI
Sbjct: 26 SVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILI 85
Query: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMP--------- 131
+FVSYFGSRVHRPR+IG G + +A ++TLPHF+SEPY+Y S +
Sbjct: 86 IFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQAELCQK 145
Query: 132 --QDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGI 189
QD S C TT P S S+ G+M VAQ L G+G VPIQPFGI
Sbjct: 146 HWQDLPPSKCHSTTQNPQKETS-------------SMWGLMVVAQLLAGIGTVPIQPFGI 192
Query: 190 SYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPR 249
SY+DDF+ SNSPLY+ ILFA+++ GP + LGS+ML+++VD ++ ++L DPR
Sbjct: 193 SYVDDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPR 252
Query: 250 WVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSK 309
W+GAWWLG LI++ + L + P+FFFP+ MP K T ARK +++ S+
Sbjct: 253 WIGAWWLGLLISSALLVLTSFPFFFFPRAMP-------IGAKRAPATADEARKLEEAKSR 305
Query: 310 QSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMA 369
S ++ FIK FP + L+ L + +F+LVVL+Q SS+ AG++
Sbjct: 306 GS-------------------LVDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLS 346
Query: 370 TFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKR----LHLGPVGCGALCL 425
TFL KFLE+Q+ +A+YAN LIG ++ P+ +G++ GG+L+KR L P +
Sbjct: 347 TFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIIT 406
Query: 426 LGMLLCLFFSLPLFFIGCSSHQIAGI---THQTSAHPGLELSPSCMEACSCPLDGFNPVC 482
+ M+LC +PLFF+GCS+ +A + + +S HP SP+C CSCP F+PVC
Sbjct: 407 ISMILC----VPLFFMGCSTPTVAEVYPPSTSSSIHP---QSPACRRDCSCPDSIFHPVC 459
Query: 483 DPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGN-PVLAGSCDSTCSHLVVP 541
+EY++PCHAGCS+ + + + Q+ Y NCSCV G+ GSC C+H ++P
Sbjct: 460 G-DNGIEYLSPCHAGCSN-INMSSATSKQLIYLNCSCVTGGSASAKTGSCPVPCAHFLLP 517
Query: 542 FLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAID 601
+ L+S S +AC++H P +M++LR V +E+K+ A+G+QF+ +R+LAW+PSP ++G ID
Sbjct: 518 AIFLISFVSLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTID 577
Query: 602 TTCVHW-ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGS--VICF 644
+C+ W +L GRR C YY+ND LR+R++GLQ +K ++CF
Sbjct: 578 HSCIRWNSLCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCF 623
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 384 bits (985), Expect = e-106
Identities = 223/667 (33%), Positives = 353/667 (52%), Gaps = 45/667 (6%)
Query: 21 SVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
S F NIK+F++ L LAQ + YL S ++T+E+RF L S G++AS E+GN ALI
Sbjct: 34 SCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALI 93
Query: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCL 140
+FVSYFG+R HRPR+IG G I++AL LL LP F++ Y+Y+ + E +C
Sbjct: 94 LFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYE--AGEIRWGAEGRDVCA 151
Query: 141 PTTSAPASAPSNGN-CSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNS 199
S P C + T T + + ++ AQ LLG+G P+QP G+SYIDD
Sbjct: 152 ANGSGGDEGPDPDLICRNRTATNMMYL--LLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209
Query: 200 NSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFL 259
+S LY+GILF + + GP F LGS ++YVD + + +T DPRW+GAWW GFL
Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269
Query: 260 IAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQ 319
+ + +++ F FP+ +P PA + + + + E K
Sbjct: 270 LCGALLFFSSLLMFGFPQSLPPH--------------SEPAMESEQAMLSEREYERPKPS 315
Query: 320 DGLVQ--IAP--NLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 375
+G+++ + P + + Q ++V P+V L +P+F ++L+ ++ AG A FL K+
Sbjct: 316 NGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKY 375
Query: 376 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 435
LE+QF++T S AN L+G + P +GI +GG+LVK+L L +G + +L L+
Sbjct: 376 LEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACY 435
Query: 436 LPLFFIGCSSHQIAGIT--HQTSAHPGLELSP--SCMEACSCPLDGFNPVCDPSTRVEYI 491
+ F+GC + +AG+T + S PG L P C C C D F PVC + + Y+
Sbjct: 436 VSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCG-ADGITYL 494
Query: 492 TPCHAGCSSWVVQDALDNSQVFYTNCSCV----VEGNPVLAGSCDST-CSHLVVPFLLLV 546
+ C AGC+S T C+C+ E V+ G C S C + FL ++
Sbjct: 495 SACFAGCNS-----------TNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFLCVM 543
Query: 547 SLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVH 606
+ S + + TPS ++++R V E K+ A+G+ F+ LR+L ++P P+I G+ ID+TC+
Sbjct: 544 CICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLF 603
Query: 607 WALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKE-ARTKESRS 665
W+ CG + C Y+N + R ++ + K+ + I + LR+ K + E
Sbjct: 604 WSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHEGGL 663
Query: 666 SPAVEQQ 672
S + E Q
Sbjct: 664 STSTEYQ 670
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 383 bits (983), Expect = e-106
Identities = 219/650 (33%), Positives = 347/650 (53%), Gaps = 44/650 (6%)
Query: 21 SVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
S F NIK+F++ L LAQ + YL S ++T+E+RF L S G++AS E+GN ALI
Sbjct: 34 SCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALI 93
Query: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCL 140
+FVSYFG+R HRPR+IG G I++AL LL LP F++ Y+Y+ + E +C
Sbjct: 94 LFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYE--AGEIRWGAEGRDVCA 151
Query: 141 PTTSAPASAPSNGN-CSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNS 199
S P C + T T + + ++ AQ LLG+G P+QP G+SYIDD
Sbjct: 152 ANGSGGDEGPDPDLICRNRTATNMMYL--LLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209
Query: 200 NSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFL 259
+S LY+GILF + + GP F LGS ++YVD + + +T DPRW+GAWW GFL
Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269
Query: 260 IAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQ 319
+ + +++ F FP+ +P PA + + + + E K
Sbjct: 270 LCGALLFFSSLLMFGFPQSLPPH--------------SEPAMESEQAMLSEREYERPKPS 315
Query: 320 DGLVQ--IAP--NLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 375
+G+++ + P + + Q ++V P+V L +P+F ++L+ ++ AG A FL K+
Sbjct: 316 NGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKY 375
Query: 376 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 435
LE+QF++T S AN L+G + P +GI +GG+LVK+L L +G + +L L+
Sbjct: 376 LEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACY 435
Query: 436 LPLFFIGCSSHQIAGIT--HQTSAHPGLELSP--SCMEACSCPLDGFNPVCDPSTRVEYI 491
+ F+GC + +AG+T + S PG L P C C C D F PVC + + Y+
Sbjct: 436 VSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCG-ADGITYL 494
Query: 492 TPCHAGCSSWVVQDALDNSQVFYTNCSCV----VEGNPVLAGSCDST-CSHLVVPFLLLV 546
+ C AGC+S T C+C+ E V+ G C S C + FL ++
Sbjct: 495 SACFAGCNS-----------TNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFLCVM 543
Query: 547 SLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVH 606
+ S + + TPS ++++R V E K+ A+G+ F+ LR+L ++P P+I G+ ID+TC+
Sbjct: 544 CICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLF 603
Query: 607 WALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDK 656
W+ CG + C Y+N + R ++ + K+ + I + LR+ K
Sbjct: 604 WSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYK 653
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 352 bits (904), Expect = 5e-97
Identities = 206/647 (31%), Positives = 342/647 (52%), Gaps = 41/647 (6%)
Query: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
Query: 146 --PASA--PSNGNCSSYTETQHLSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSN 200
P S S S+ E S + I +F+ L G+G PIQP GI+Y+DDFA N
Sbjct: 161 QLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDN 220
Query: 201 SPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLI 260
+ Y+G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LI
Sbjct: 221 AAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLI 280
Query: 261 AAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQD 320
A LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 281 AGIISLLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTD 324
Query: 321 GLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQF 380
N +++ + F L +P++ L + + + GM T+ PK++E+Q+
Sbjct: 325 YQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQY 384
Query: 381 SITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFF 440
++S AN +IG ++ P+V +GI GG+++K+ + G L L + L LF
Sbjct: 385 GQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFA 444
Query: 441 IGCSSHQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCH 495
+GC + +AG+T + ++ L C C C + P+C + Y++ C
Sbjct: 445 LGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACL 503
Query: 496 AGCSSWVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVS 547
AGC + + + NC+CV GN + G C D+ C + + FL++
Sbjct: 504 AGCQT----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
Query: 548 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 607
+ S L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W
Sbjct: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
Query: 608 ALS-CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653
CG R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 620 GFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 348 bits (894), Expect = 7e-96
Identities = 220/683 (32%), Positives = 335/683 (49%), Gaps = 66/683 (9%)
Query: 22 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
Query: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 136
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
Query: 137 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 196
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 243 TATLEPPACPKDSGGNN---------HWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
Query: 197 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 256
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
Query: 257 GFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGES 315
GFL+ A A+ L P F FPK++P + K++ + + V AV+D K K + S+Q+ +
Sbjct: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKV 409
Query: 316 TKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 375
+ G + ++ PR ++ L + FL V LS S++ TF+PKF
Sbjct: 410 SSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKF 458
Query: 376 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 435
+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ + L
Sbjct: 459 IESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCF 518
Query: 436 LPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEY 490
LF +GC S + GI + P L L+ SC C C + + PVC S + Y
Sbjct: 519 STLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITY 577
Query: 491 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV--------------------------EGN 524
PC AGC V L YT C+CV E
Sbjct: 578 FNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENG 634
Query: 525 PVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFL 584
++G C TC+ L+ PFL+ + + + + + ++ LR V+ E++ A+G+QF+ L
Sbjct: 635 YAVSGKCKRTCNTLI-PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLL 693
Query: 585 RILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICF 644
R LA++P+P+ G+ IDTTC+ W CG + C YN R + GL K I
Sbjct: 694 RTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFI 753
Query: 645 ALVLAVLRQQDKEARTKESRSSP 667
L ++ ++ + + R P
Sbjct: 754 FLAWYSIKYKEDGLQRRRQREFP 776
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 340 bits (873), Expect = 2e-93
Identities = 199/620 (32%), Positives = 327/620 (52%), Gaps = 41/620 (6%)
Query: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
Query: 146 --PASA--PSNGNCSSYTETQHLSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSN 200
P S S S+ E S + I +F+ L G+G PIQP GI+Y+DDFA N
Sbjct: 161 QLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDN 220
Query: 201 SPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLI 260
+ Y+G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LI
Sbjct: 221 AAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLI 280
Query: 261 AAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQD 320
A LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 281 AGIISLLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTD 324
Query: 321 GLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQF 380
N +++ + F L +P++ L + + + GM T+ PK++E+Q+
Sbjct: 325 YQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQY 384
Query: 381 SITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFF 440
++S AN +IG ++ P+V +GI GG+++K+ + G L L + L LF
Sbjct: 385 GQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFA 444
Query: 441 IGCSSHQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCH 495
+GC + +AG+T + ++ L C C C + P+C + Y++ C
Sbjct: 445 LGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACL 503
Query: 496 AGCSSWVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVS 547
AGC + + + NC+CV GN + G C D+ C + + FL++
Sbjct: 504 AGCQT----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
Query: 548 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 607
+ S L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W
Sbjct: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
Query: 608 ALS-CGRRAVCRYYNNDLLR 626
CG R CR Y++++ R
Sbjct: 620 GFKRCGSRGSCRLYDSNVFR 639
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 339 bits (870), Expect = 4e-93
Identities = 213/662 (32%), Positives = 342/662 (51%), Gaps = 49/662 (7%)
Query: 24 HNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFV 83
+ K+F+ S +A+ + +K SI+ +E+RF +SS +GL+ E+GN +IVFV
Sbjct: 25 NGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFV 84
Query: 84 SYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTT 143
SYFGS++HRP++IG G +L+ +L +LPHF YRY + + ++ +SL T
Sbjct: 85 SYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLS--TC 142
Query: 144 SAPASAPSNGNCSSYTETQHLSVVG-----IMFVAQTLLGVGGVPIQPFGISYIDDFAHN 198
+ NG E + G +F+ L G+G PI P GISYIDDFA
Sbjct: 143 LINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKE 202
Query: 199 SNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGF 258
+S LYLG L A+ M+GP + F LGSL ++YVDI + I +T KD RWVGAWWLGF
Sbjct: 203 GHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGF 262
Query: 259 LIAAGAVALAAIPYFFFPK--EMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGEST 316
L++ +++IP+FF PK P+++R++ VL D + + + G++
Sbjct: 263 LVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDD----RNQTANLTNQGKNV 318
Query: 317 KKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFL 376
K V F + +L L + IFLL+ L QV S G T++ K++
Sbjct: 319 TK-----------NVTGFFQSLKSILTNPL-YVIFLLLTLLQV---SSFIGSFTYVFKYM 363
Query: 377 ERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSL 436
E+Q+ +AS+AN L+G ++ P+V G+ +GG ++K+ L VG L ++ F L
Sbjct: 364 EQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQL 423
Query: 437 PLFFIGCSSHQIAGIT------HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEY 490
F + C S +AG+T + ++H + LS C C+C + PVC + + Y
Sbjct: 424 LYFPLICESKSVAGLTLTYDGNNSVASHVDVPLS-YCNSECNCDESQWEPVCG-NNGITY 481
Query: 491 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------EGNPVLAGSC--DSTCSHLVVPF 542
++PC AGC S + VFY NCSCV G C D+TC+ +
Sbjct: 482 LSPCLAGCKS---SSGIKKHTVFY-NCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIY 537
Query: 543 LLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDT 602
+ + + S + T +L ++ V+ E K LA+G Q M +R L + +P+ G+ ID
Sbjct: 538 VAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDK 597
Query: 603 TCVHWAL-SCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 661
TC+ W+ SCG + CR YN+ ++GL + +++ + + + ++++ + TK
Sbjct: 598 TCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTK 657
Query: 662 ES 663
S
Sbjct: 658 AS 659
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 331 bits (849), Expect = 1e-90
Identities = 213/690 (30%), Positives = 348/690 (50%), Gaps = 52/690 (7%)
Query: 11 ASPDPQDVRPSVFHN-IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLA 69
A P + + + + N +K+F+ SL +A+ + + +KSSI +E+RF +SS G +
Sbjct: 11 AEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFID 70
Query: 70 SFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN----T 125
E+GN +IVFVSYFGS++HRP++IG G ++ + G+L LPHF YRY
Sbjct: 71 GSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNIN 130
Query: 126 SPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQ 185
S E+ L S ++P E+ + + F+ L G+G PI
Sbjct: 131 SSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYV-FMGNMLRGIGETPIV 189
Query: 186 PFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTI 245
P G+SYIDDFA +S LYLGIL A+ M+GP + F LGSL ++YVDI + I +T
Sbjct: 190 PLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITP 249
Query: 246 KDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQFRRKVLAVTDSPARKG 303
D RWVGAWWL FL++ +++IP+FF P+ P+++R+ VL D
Sbjct: 250 TDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDE----- 304
Query: 304 KDSPSKQSPGESTKKQDGLVQIAPNLT--VIQFIKVFPRVLLQTLRHPIFLLVVLSQVCL 361
KD + L N+T V F + F + L +P++++ VL +
Sbjct: 305 KDQTA------------NLTNQGKNITKNVTGFFQSFKSI----LTNPLYVMFVLLTLLQ 348
Query: 362 SSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCG 421
S G T++ K++E+Q+ +S AN+L+G ++ P G+ +GG ++K+ L VG
Sbjct: 349 VSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIA 408
Query: 422 ALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHPGLELSPSCMEACSCPL 475
++ L F L FFI C + +AG+T + ++H + LS C C+C
Sbjct: 409 KFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLS-YCNSDCNCDE 467
Query: 476 DGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------EGNPVLAG 529
+ PVC + + YI+PC AGC S + + + + NCSC+ G
Sbjct: 468 SQWEPVCG-NNGITYISPCLAGCKS----SSGNKKPIVFYNCSCLEVTGLQNRNYSAHLG 522
Query: 530 SC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRIL 587
C D C+ F+ + L + L T MLI++ V+ E K+LA+G M +R L
Sbjct: 523 ECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRAL 582
Query: 588 AWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFAL 646
+ +P+ G+ IDTTC+ W+ +CG R CR YN+ ++GL + S++ + +
Sbjct: 583 GGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYII 642
Query: 647 VLAVLRQQDKEARTKESRSSPAVEQQLLVS 676
++ ++++ +E S + +++ L S
Sbjct: 643 LIYAMKKKYQEKDINASENGSVMDEANLES 672
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 325 bits (832), Expect = 1e-88
Identities = 197/642 (30%), Positives = 333/642 (51%), Gaps = 49/642 (7%)
Query: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
+K+F+L + +++ + Y+ S ++ +E++F + + G + E+GN LI+FVSY
Sbjct: 19 LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78
Query: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
FG+++HRP MIG G +++ L L +LPHF+ Y Y++T + LC+ +
Sbjct: 79 FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138
Query: 146 ---PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSP 202
P PS C+ E + L V ++ V + G+G PI P GISYI+DFA NSP
Sbjct: 139 ILRPTQDPSE--CTK--EVKSLMWVYVL-VGNIVRGMGETPILPLGISYIEDFAKFENSP 193
Query: 203 LYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAA 262
LY+G++ ++GP + L S +YVD + + +T D RWVGAWW GFLI A
Sbjct: 194 LYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICA 253
Query: 263 GAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGL 322
G L AIP+FF P +PKE E T++ K ++ ++ E K++ G+
Sbjct: 254 GVNVLTAIPFFFLPNTLPKEGLE----------TNADIIKNENEDKQKE--EVKKEKYGI 301
Query: 323 VQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSI 382
K F + +PI++L +L V + M +F+PK+LE+Q+ I
Sbjct: 302 T------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGI 349
Query: 383 TASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFI 441
++S A L+G + P + +G ++GG+++K+ + + C L +L L + L F +
Sbjct: 350 SSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLM 408
Query: 442 GCSSHQIAGITHQTSAHP-----GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHA 496
C + + GI P ++ C C+CP ++PVC + + Y++ C A
Sbjct: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCG-NNGLSYLSACLA 467
Query: 497 GCSSWVVQDALDNSQVFYTNCSCV-VEGN-PVLAGSCDS--TCSHLVVPFLLLVSLGSAL 552
GC + + + + NCSC+ GN + G CD CS ++ FL+L ++ S +
Sbjct: 468 GCETSIG----TGINMVFQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFI 523
Query: 553 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSC 611
L P +M++LR +K E+K+L VG+ R+ A +P+P+ G+ +D+TC+HW L C
Sbjct: 524 YSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKC 583
Query: 612 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653
G CR Y++ R ++GL + S + ++L +LR+
Sbjct: 584 GESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 325 bits (832), Expect = 1e-88
Identities = 197/642 (30%), Positives = 333/642 (51%), Gaps = 49/642 (7%)
Query: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
+K+F+L + +++ + Y+ S ++ +E++F + + G + E+GN LI+FVSY
Sbjct: 19 LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78
Query: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
FG+++HRP MIG G +++ L L +LPHF+ Y Y++T + LC+ +
Sbjct: 79 FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138
Query: 146 ---PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSP 202
P PS C+ E + L V ++ V + G+G PI P GISYI+DFA NSP
Sbjct: 139 ILRPTQDPSE--CTK--EVKSLMWVYVL-VGNIVRGMGETPILPLGISYIEDFAKFENSP 193
Query: 203 LYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAA 262
LY+G++ ++GP + L S +YVD + + +T D RWVGAWW GFLI A
Sbjct: 194 LYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICA 253
Query: 263 GAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGL 322
G L AIP+FF P +PKE E T++ K ++ ++ E K++ G+
Sbjct: 254 GVNVLTAIPFFFLPNTLPKEGLE----------TNADIIKNENEDKQKE--EVKKEKYGI 301
Query: 323 VQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSI 382
K F + +PI++L +L V + M +F+PK+LE+Q+ I
Sbjct: 302 T------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGI 349
Query: 383 TASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFI 441
++S A L+G + P + +G ++GG+++K+ + + C L +L L + L F +
Sbjct: 350 SSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLM 408
Query: 442 GCSSHQIAGITHQTSAHP-----GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHA 496
C + + GI P ++ C C+CP ++PVC + + Y++ C A
Sbjct: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCG-NNGLSYLSACLA 467
Query: 497 GCSSWVVQDALDNSQVFYTNCSCV-VEGN-PVLAGSCDS--TCSHLVVPFLLLVSLGSAL 552
GC + + + + NCSC+ GN + G CD CS ++ FL+L ++ S +
Sbjct: 468 GCETSIG----TGINMVFQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFI 523
Query: 553 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSC 611
L P +M++LR +K E+K+L VG+ R+ A +P+P+ G+ +D+TC+HW L C
Sbjct: 524 YSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKC 583
Query: 612 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653
G CR Y++ R ++GL + S + ++L +LR+
Sbjct: 584 GESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 311 bits (797), Expect = 1e-84
Identities = 206/642 (32%), Positives = 316/642 (49%), Gaps = 59/642 (9%)
Query: 47 LKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALA 106
+K S + +E+RF +SS GL+ E+GN +IVFVSYFGS++HRP++IG G L+
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 107 GLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSV 166
+LM LPHF YRY + D ++ ++L P N S E +
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNL--PNCLINQMLSLNRTPSEIIERGCVKE 118
Query: 167 VG-----IMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFG 221
G +F+ L G+G PI P GISYIDDFA +S LYLG + + M G AF
Sbjct: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178
Query: 222 LGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFP--KEM 279
LGSL ++YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF P
Sbjct: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238
Query: 280 PKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT-----VIQF 334
P+++R++ VL K D QIA NLT + +
Sbjct: 239 PQKERKVSLFLHVL-----------------------KTNDKRNQIA-NLTNRRKYITKN 274
Query: 335 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 394
+ F + L L +P++++ V+ + S T++ K +E+Q+ +AS N L+G L
Sbjct: 275 VTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVL 334
Query: 395 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-- 452
+ P+V +G+ GG ++K+ L VG L + L + FF+ C S +AG+T
Sbjct: 335 ALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLT 394
Query: 453 ----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALD 508
+H + LS C C+C + PVC + + Y++PC AGC S + +
Sbjct: 395 YDGNSPVRSHVDVPLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS----SSGN 448
Query: 509 NSQVFYTNCSCVV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPS 560
+ + NCSCV + G C D C+ + ++ L + L + T
Sbjct: 449 KEPIVFYNCSCVEVIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSY 508
Query: 561 FMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRY 619
+L++R V+ E K LA+G M +R L + P+ G+ IDTTC+ W+ SCG R CR
Sbjct: 509 SVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRI 568
Query: 620 YNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 661
YN+ L F GL+ ++ + + V+R++ TK
Sbjct: 569 YNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTK 610
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 300 bits (767), Expect = 4e-81
Identities = 186/642 (28%), Positives = 315/642 (49%), Gaps = 80/642 (12%)
Query: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
Query: 146 PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYL 205
V +M S S +
Sbjct: 161 QLP------------------VSVM--------------------------EKSKSKISN 176
Query: 206 GILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAV 265
G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LIA
Sbjct: 177 GCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIIS 236
Query: 266 ALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQI 325
LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 237 LLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTDYQTPQ 280
Query: 326 APNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITAS 385
N +++ + F L +P++ L + + + GM T+ PK++E+Q+ ++S
Sbjct: 281 GENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSS 340
Query: 386 YANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSS 445
AN +IG ++ P+V +GI GG+++K+ + G L L + L LF +GC +
Sbjct: 341 RANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCEN 400
Query: 446 HQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSS 500
+AG+T + ++ L C C C + P+C + Y++ C AGC +
Sbjct: 401 SDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT 459
Query: 501 WVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSAL 552
+ + NC+CV GN + G C D+ C + + FL++ + S
Sbjct: 460 ----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYT 515
Query: 553 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-C 611
L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W C
Sbjct: 516 LSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRC 575
Query: 612 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653
G R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 576 GSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 297 bits (761), Expect = 2e-80
Identities = 188/618 (30%), Positives = 308/618 (49%), Gaps = 67/618 (10%)
Query: 29 FVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFG 87
F+L + LL + Q ++++G + SISTVEKR+ + S +GL++S ++ L +FVS+FG
Sbjct: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
Query: 88 SRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPA 147
R H+PR + + A ++ L L+ +LP F S Y+ + + C+ T ++ +
Sbjct: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFED---------TCVTTRNSTS 217
Query: 148 SAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGI 207
S + S+Y + + + Q LLG GG P+ G +++DD S LY+G
Sbjct: 218 CTSSTSSLSNY--------LYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGT 269
Query: 208 LFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVAL 267
+A++++GP + + LG +L +Y+D+ M E +T DPRW+GAWW+GFL++
Sbjct: 270 GYAMSILGPAIGYVLGGQLLTIYIDV-AMGE-STDVTEDDPRWLGAWWIGFLLSWIFAWS 327
Query: 268 AAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAP 327
IP+ FPK +P + + GK S + QS + K
Sbjct: 328 LIIPFSCFPKHLP---------------GTAEIQAGKTSQAHQSNSNADVKFG------- 365
Query: 328 NLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYA 387
+ IK FP L +++ +F+ +VLS + + G ATFLPKF+E QF +T+S+A
Sbjct: 366 -----KSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
Query: 388 NLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQ 447
L G + P +G ++GG LV + + L + L S + C +
Sbjct: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
Query: 448 IAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDA 506
AG++ + L L C C+C + PVC V+Y +PC AGCS+ V A
Sbjct: 481 FAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDG--VQYFSPCFAGCSNPV---A 535
Query: 507 LDNSQVFYTNCSCVVE-----------GNPVLAGSCDSTCSHLVVPFLLLVSLGSALACL 555
+V+Y NCSC+ G AG C++ C+ L + FL + + +
Sbjct: 536 HRKPKVYY-NCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPI-FLCIFFIVIIFTFM 593
Query: 556 THTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRR 614
TP + ILR V ++LA+GIQFM LR+L +P P+I G ID+TC+ W ++ CG +
Sbjct: 594 AGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIK 653
Query: 615 AVCRYYNNDLLRNRFIGL 632
C Y+N + + + +
Sbjct: 654 GACWIYDNIKMAHMLVAI 671
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 290 bits (741), Expect = 4e-78
Identities = 188/630 (29%), Positives = 309/630 (49%), Gaps = 62/630 (9%)
Query: 28 LFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFG 87
LF LC + L + ++G++ + I+++E+R+ L S SGL+AS ++ + FVSYFG
Sbjct: 106 LFFLCAAAF-LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFG 164
Query: 88 SRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPA 147
H+PR +G+G +L+ L+ LPHF + Y ++ D C P
Sbjct: 165 GSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRY--------EVELDAGVRTC-PANPGAV 215
Query: 148 SAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGI 207
A S S Y + + Q L GVG P+ G++Y+D+ +S SP+Y+ I
Sbjct: 216 CADSTSGLSRYQL--------VFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAI 267
Query: 208 LFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVAL 267
+ ++GP + +G +L +Y ++ + E LT + P WVGAWW+GFL + A
Sbjct: 268 FYTAAILGPAAGYLIGGALLNIYTEMGRRTE----LTTESPLWVGAWWVGFLGSGAAAFF 323
Query: 268 AAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAP 327
A+P +P+++P +R R + + KDS S GE++ G
Sbjct: 324 TAVPILGYPRQLPGSQRYAVMRA-------AEMHQLKDS----SRGEASNPDFG------ 366
Query: 328 NLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYA 387
+ I+ P + L++P F+L+ L+ +++ GM+TF PKFLE QFS++AS A
Sbjct: 367 -----KTIRDLPLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEA 421
Query: 388 NLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQ 447
L G L P+ G +GG V +L L CL ++ L + +F + C S
Sbjct: 422 ATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSL-LGILVFSLHCPSVP 480
Query: 448 IAGITHQTSA----HPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVV 503
+AG+T L L+ C ACSC + ++PVC S + Y + CHAGC +
Sbjct: 481 MAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSPVCG-SDGLMYFSLCHAGCPA-AT 538
Query: 504 QDALDNSQVFYTNCSCVVEG-----NPVLAGSCDSTCSH--LVVPFLLLVSLGSALACLT 556
+ +D +V Y +CSC+ + AG C STC L++ F+ +V + L+ +
Sbjct: 539 ETNVDGQKV-YRDCSCIPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSI- 596
Query: 557 HTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAV 616
P+ LR V+ ++ A+GIQ++ +RIL +P P+ G ID C+ W CG++
Sbjct: 597 --PALTATLRCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGS 654
Query: 617 CRYYNNDLLRNRFIGLQFFFKTGSVICFAL 646
C Y N + + + +K V+ FA+
Sbjct: 655 CLVYQNSAMSRYILIMGLLYKVLGVLFFAI 684
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 288 bits (737), Expect = 1e-77
Identities = 187/581 (32%), Positives = 282/581 (48%), Gaps = 66/581 (11%)
Query: 22 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
Query: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 136
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
Query: 137 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 196
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 243 TATLEPPACPKDSGGN---------NHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
Query: 197 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 256
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
Query: 257 GFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGES 315
GFL+ A A+ L P F FPK++ P+ K++ + + V AV+D K K + S+Q+ +
Sbjct: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKV 409
Query: 316 TKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 375
+ G + ++ PR ++ L + FL V LS S++ TF+PKF
Sbjct: 410 SSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKF 458
Query: 376 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 435
+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ + L
Sbjct: 459 IESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCF 518
Query: 436 LPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEY 490
LF +GC S + GI + P L L+ SC C C + + PVC S + Y
Sbjct: 519 STLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITY 577
Query: 491 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV--------------------------EGN 524
PC AGC V L YT C+CV E
Sbjct: 578 FNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENG 634
Query: 525 PVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLIL 565
++G C TC+ L +PFL+ + + + + + ++ L
Sbjct: 635 YAVSGKCKRTCNTL-IPFLVFLFIVTFITACAQPSAIIVTL 674
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 272 bits (696), Expect = 7e-73
Identities = 168/538 (31%), Positives = 272/538 (50%), Gaps = 41/538 (7%)
Query: 108 LLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA--PASA--PSNGNCSSYTETQH 163
LL+ +P F E Y+Y+ SP S CL +S+ P S S S+ E
Sbjct: 6 LLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSSQLPVSVMEKSKSKISNECEVDT 64
Query: 164 LSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGL 222
S + I +F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F L
Sbjct: 65 SSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLL 124
Query: 223 GSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKE 282
GSL +LYVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 125 GSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR- 183
Query: 283 KRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVL 342
S +R+ +S S++S D N +++ + F L
Sbjct: 184 ---------------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSL 228
Query: 343 LQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVG 402
+P++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +G
Sbjct: 229 KNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALG 288
Query: 403 IVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSA 457
I GG+++K+ + G L L + L LF +GC + +AG+T + +
Sbjct: 289 IFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVS 348
Query: 458 HPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNC 517
+ L C C C + P+C + Y++ C AGC + + + NC
Sbjct: 349 YHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNC 403
Query: 518 SCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVK 569
+CV GN + G C D+ C + + FL++ + S L P ++L+LR +K
Sbjct: 404 TCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIK 463
Query: 570 KEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLR 626
+ K+ A+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R
Sbjct: 464 PQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 521
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 201 bits (510), Expect = 2e-51
Identities = 154/648 (23%), Positives = 281/648 (43%), Gaps = 67/648 (10%)
Query: 24 HNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFV 83
+NI+ F++ + +L + Q ++ G + SI +K + L + L ++ + + +F+
Sbjct: 103 NNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFI 162
Query: 84 SYFGSRVHRPRMIGYGA--ILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLP 141
+++G R ++I + A L+ L LL P I+E + ED+ ++ K
Sbjct: 163 AFYGDR---KKVIWFVASSFLIGLGSLLCAFPS-INEENKQSKVGIEDICEEIKVV---- 214
Query: 142 TTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNS 201
C S + + + QT+ G+ G+P+ GI++ID+ ++
Sbjct: 215 -----------SGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSA 263
Query: 202 PLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIA 261
+YLGI +M+G L + LG+ +++ V N ++ P W+ WW+ FL A
Sbjct: 264 GIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFA 321
Query: 262 AGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDG 321
A IP FP MP R +RK L DS +
Sbjct: 322 AVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSRLKD------------------- 362
Query: 322 LVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFS 381
+++ N IK L +++P+ + + LS+ + G + FLP +LE QF
Sbjct: 363 -LKLGTN------IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFI 415
Query: 382 ITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 441
+T + A L G + P +G ++GGV+V L + ++ ++ L + + F+
Sbjct: 416 LTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFV 475
Query: 442 GCSSHQIAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSS 500
C+ Q AGI L L+ C E C C ++ +C +EY +PC AGC+
Sbjct: 476 RCNPVQFAGINEDYDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDD-IEYFSPCFAGCTY 534
Query: 501 WVVQDALDNSQVFYTNCSCVVEG----------NPVLAGSCDSTCSHLVVPFLLLVSLGS 550
Q N + Y NCSC+ EG G CD+ C L + F+ +
Sbjct: 535 SKAQ----NQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPL-FIAFIFSTL 589
Query: 551 ALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS 610
+ + P + + R V + ++LA+G+ ++ LRI +P P I + +T+C+ ++
Sbjct: 590 IFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVN 649
Query: 611 -CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKE 657
CG C YN + +G+ F K ++I + + +++ E
Sbjct: 650 KCGHTGRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 191 bits (484), Expect = 3e-48
Identities = 109/296 (36%), Positives = 162/296 (54%), Gaps = 19/296 (6%)
Query: 22 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
Query: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 136
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
Query: 137 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 196
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 243 TATLEPPACPKDSGGN---------NHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
Query: 197 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 256
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
Query: 257 GFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQS 311
GFL+ A A+ L P F FPK++ P+ K++ + + V AV+D K K + S+Q+
Sbjct: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQA 405
Score = 135 bits (339), Expect = 2e-31
Identities = 89/307 (28%), Positives = 137/307 (44%), Gaps = 36/307 (11%)
Query: 392 GCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGI 451
G + PS VGIV+GG ++K+L LG L ++ + L LF +GC S + GI
Sbjct: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479
Query: 452 THQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDA 506
+ P L L+ SC C C + + PVC S + Y PC AGC V
Sbjct: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITYFNPCLAGC---VNSGN 535
Query: 507 LDNSQVFYTNCSCVV--------------------------EGNPVLAGSCDSTCSHLVV 540
L YT C+CV E ++G C TC+ L+
Sbjct: 536 LSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLI- 594
Query: 541 PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI 600
PFL+ + + + + + ++ LR V+ E++ A+G+QF+ LR LA++P+P+ G+ I
Sbjct: 595 PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVI 654
Query: 601 DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART 660
DTTC+ W CG + C YN R + GL K I L ++ ++ +
Sbjct: 655 DTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQR 714
Query: 661 KESRSSP 667
+ R P
Sbjct: 715 RRQREFP 721
>gi|186928854 mitochondrial ribosomal protein S31 [Homo sapiens]
Length = 395
Score = 32.7 bits (73), Expect = 1.1
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 9/114 (7%)
Query: 582 MFLRILAWMP------SPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFF 635
MF R+ ++P P+ GS +T+ L R RY ++ LL +Q +
Sbjct: 1 MFPRVSTFLPLRPLSRHPLSSGSP-ETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRY 59
Query: 636 FKTGSVICFALVLAVLRQQDKEARTKESRSSPA--VEQQLLVSGPGKKPEDSRV 687
F T SVIC +R ++ T ES+ S ++ LL G K E S V
Sbjct: 60 FGTNSVICSKKDKQSVRTEETSKETSESQDSEKENTKKDLLGIIKGMKVELSTV 113
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 31.2 bits (69), Expect = 3.3
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 194 DFAHNSNSPLYLGILFA----VTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDP 248
D H SPL + + VT GPGL G+ + V+ EGG+SL I+ P
Sbjct: 1847 DNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGP 1905
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 31.2 bits (69), Expect = 3.3
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 194 DFAHNSNSPLYLGILFA----VTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDP 248
D H SPL + + VT GPGL G+ + V+ EGG+SL I+ P
Sbjct: 1839 DNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGP 1897
>gi|148727298 keratin associated protein 10-6 [Homo sapiens]
Length = 365
Score = 30.8 bits (68), Expect = 4.4
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 9/94 (9%)
Query: 442 GCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSW 501
GC+S Q+S P S C +AC P+ PVC T E + C C
Sbjct: 199 GCTSSCTPSCCQQSSCQPTCCTSSPCQQACCVPVCCV-PVCCVPTCSEDSSSC---CQQS 254
Query: 502 VVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTC 535
Q A S C CV PV +G+ S C
Sbjct: 255 SCQPACCTSSPCQHAC-CV----PVCSGASTSCC 283
Score = 30.4 bits (67), Expect = 5.7
Identities = 24/94 (25%), Positives = 30/94 (31%)
Query: 442 GCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSW 501
GC+S Q+S S C +AC P+ C P V + C
Sbjct: 80 GCTSSCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVCCVSVCCGDSSCCQQS 139
Query: 502 VVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTC 535
Q A S C V PV +G S C
Sbjct: 140 SCQSACCTSSPCQQACCVPVCCKPVCSGISSSCC 173
>gi|4504093 G protein-coupled receptor 32 [Homo sapiens]
Length = 356
Score = 30.4 bits (67), Expect = 5.7
Identities = 14/50 (28%), Positives = 28/50 (56%)
Query: 331 VIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQF 380
V+ + ++ RV+L+ + HP LL++ + L + + + FL F+ R F
Sbjct: 274 VVLLVHLWRRVMLKEIYHPRMLLILQASFALGCVNSSLNPFLYVFVGRDF 323
>gi|26051246 tumor necrosis factor ligand superfamily, member 13
isoform beta proprotein [Homo sapiens]
Length = 234
Score = 30.0 bits (66), Expect = 7.4
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 237 PEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQ-FRRKV--L 293
P G + +++P A WL + A GAVA A + ++ ELQ RR+V L
Sbjct: 14 PPGNMGGPVREPALSVALWLSWGAALGAVACA--------MALLTQQTELQSLRREVSRL 65
Query: 294 AVTDSPARKGKDSPSKQSPGEST 316
T P++ G+ P + P +S+
Sbjct: 66 QGTGGPSQNGEGYPWQSLPEQSS 88
>gi|4507599 tumor necrosis factor ligand superfamily, member 13
isoform alpha proprotein [Homo sapiens]
Length = 250
Score = 30.0 bits (66), Expect = 7.4
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 237 PEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQ-FRRKV--L 293
P G + +++P A WL + A GAVA A + ++ ELQ RR+V L
Sbjct: 14 PPGNMGGPVREPALSVALWLSWGAALGAVACA--------MALLTQQTELQSLRREVSRL 65
Query: 294 AVTDSPARKGKDSPSKQSPGEST 316
T P++ G+ P + P +S+
Sbjct: 66 QGTGGPSQNGEGYPWQSLPEQSS 88
>gi|26051248 tumor necrosis factor ligand superfamily, member 13
isoform gamma proprotein [Homo sapiens]
Length = 247
Score = 30.0 bits (66), Expect = 7.4
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 237 PEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQ-FRRKV--L 293
P G + +++P A WL + A GAVA A + ++ ELQ RR+V L
Sbjct: 14 PPGNMGGPVREPALSVALWLSWGAALGAVACA--------MALLTQQTELQSLRREVSRL 65
Query: 294 AVTDSPARKGKDSPSKQSPGEST 316
T P++ G+ P + P +S+
Sbjct: 66 QGTGGPSQNGEGYPWQSLPEQSS 88
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 30.0 bits (66), Expect = 7.4
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 10/81 (12%)
Query: 461 LELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV 520
L+ C CSC DG+ P D +E S ++D L ++ +C CV
Sbjct: 382 LDAEGPCTWPCSCEDDGY-PALDLDAGLE---------PSPGLEDPLLDAGTTVLSCGCV 431
Query: 521 VEGNPVLAGSCDSTCSHLVVP 541
G+P L G S L P
Sbjct: 432 SAGSPGLGGPLGSLLDRLKPP 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,427,573
Number of Sequences: 37866
Number of extensions: 1273329
Number of successful extensions: 4406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4233
Number of HSP's gapped (non-prelim): 76
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.