Guide to the Human Genome
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Search of human proteins with 223278374

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223278374 DNA cross-link repair 1A [Homo sapiens]
         (1040 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223278374 DNA cross-link repair 1A [Homo sapiens]                 2118   0.0  
gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S. cerevisia...   160   8e-39
gi|76496497 artemis protein isoform a [Homo sapiens]                   96   1e-19
gi|76496501 artemis protein isoform c [Homo sapiens]                   63   2e-09
gi|76496499 artemis protein isoform d [Homo sapiens]                   63   2e-09
gi|76496495 artemis protein isoform b [Homo sapiens]                   61   6e-09
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               38   0.057
gi|17505234 nucleolar and spindle associated protein 1 isoform 2...    37   0.074
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    37   0.074
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           37   0.13 
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           37   0.13 
gi|67551265 transcription factor ELYS [Homo sapiens]                   36   0.22 
gi|156119615 myosin IXA [Homo sapiens]                                 35   0.28 
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  35   0.28 
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom...    35   0.48 
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom...    35   0.48 
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    35   0.48 
gi|148747556 PIN2-interacting protein 1 [Homo sapiens]                 34   0.63 
gi|239755261 PREDICTED: hypothetical protein [Homo sapiens]            34   0.63 
gi|239749742 PREDICTED: hypothetical protein XP_002347147 [Homo ...    34   0.63 
gi|239743997 PREDICTED: hypothetical protein XP_002343013 [Homo ...    34   0.63 
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       34   0.63 
gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]              33   1.1  
gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]                33   1.1  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    33   1.4  
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         33   1.4  
gi|193804867 nucleolar and spindle associated protein 1 isoform ...    33   1.8  
gi|193804865 nucleolar and spindle associated protein 1 isoform ...    33   1.8  
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    33   1.8  
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    33   1.8  

>gi|223278374 DNA cross-link repair 1A [Homo sapiens]
          Length = 1040

 Score = 2118 bits (5489), Expect = 0.0
 Identities = 1040/1040 (100%), Positives = 1040/1040 (100%)

Query: 1    MLEDISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEV 60
            MLEDISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEV
Sbjct: 1    MLEDISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEV 60

Query: 61   KDHEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQHVSPKIRPVYDG 120
            KDHEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQHVSPKIRPVYDG
Sbjct: 61   KDHEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQHVSPKIRPVYDG 120

Query: 121  YCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQS 180
            YCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQS
Sbjct: 121  YCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQS 180

Query: 181  RAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQYFKKSPS 240
            RAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQYFKKSPS
Sbjct: 181  RAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQYFKKSPS 240

Query: 241  LTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISY 300
            LTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISY
Sbjct: 241  LTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISY 300

Query: 301  SPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCP 360
            SPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCP
Sbjct: 301  SPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCP 360

Query: 361  KVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPALAGKLAA 420
            KVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPALAGKLAA
Sbjct: 361  KVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPALAGKLAA 420

Query: 421  SVHQATKAKPDEPEFHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQ 480
            SVHQATKAKPDEPEFHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQ
Sbjct: 421  SVHQATKAKPDEPEFHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQ 480

Query: 481  PTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPS 540
            PTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPS
Sbjct: 481  PTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPS 540

Query: 541  GLKYNARHPSTKVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCK 600
            GLKYNARHPSTKVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCK
Sbjct: 541  GLKYNARHPSTKVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCK 600

Query: 601  RKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLINTE 660
            RKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLINTE
Sbjct: 601  RKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLINTE 660

Query: 661  SEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKKTCPFYKKIPGTGFTVDAFQYG 720
            SEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKKTCPFYKKIPGTGFTVDAFQYG
Sbjct: 661  SEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKKTCPFYKKIPGTGFTVDAFQYG 720

Query: 721  VVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQEQYIHPLPLDTECI 780
            VVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQEQYIHPLPLDTECI
Sbjct: 721  VVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQEQYIHPLPLDTECI 780

Query: 781  VNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRADPSMERSLLADQKVHMLYLDTT 840
            VNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRADPSMERSLLADQKVHMLYLDTT
Sbjct: 781  VNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRADPSMERSLLADQKVHMLYLDTT 840

Query: 841  YCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVCGTYSIGKEKVFLAIADVLGSKVGM 900
            YCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVCGTYSIGKEKVFLAIADVLGSKVGM
Sbjct: 841  YCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVCGTYSIGKEKVFLAIADVLGSKVGM 900

Query: 901  SQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQINFKGLQSHLKKCGGKYNQILAFR 960
            SQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQINFKGLQSHLKKCGGKYNQILAFR
Sbjct: 901  SQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQINFKGLQSHLKKCGGKYNQILAFR 960

Query: 961  PTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGT 1020
            PTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGT
Sbjct: 961  PTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGT 1020

Query: 1021 WKSRSTMEKYFREWKLEAGY 1040
            WKSRSTMEKYFREWKLEAGY
Sbjct: 1021 WKSRSTMEKYFREWKLEAGY 1040


>gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)
            [Homo sapiens]
          Length = 532

 Score =  160 bits (404), Expect = 8e-39
 Identities = 111/321 (34%), Positives = 164/321 (51%), Gaps = 37/321 (11%)

Query: 707  IPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQ 766
            IP T   VD +          +FL+H HSDH  GLS  +  P+YCS IT +LL   L V 
Sbjct: 6    IPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHRHLQVS 65

Query: 767  EQYI--------HPLPLDTECIVNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRA 818
            +Q+I        H LPLD E     + V LLDANHCPG+VM LF    GT IL+TGDFR 
Sbjct: 66   KQWIQALEVGESHVLPLD-EIGQETMTVTLLDANHCPGSVMFLFEGYFGT-ILYTGDFRY 123

Query: 819  DPSM--ERSLLADQKVHMLYLDTTYCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVC 876
             PSM  E +L   +++H LYLD T C+P    PS+QE    A +   + +  +P   +  
Sbjct: 124  TPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQE----AAHQIVQLIRKHPQHNIKI 179

Query: 877  GTYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQ 936
            G YS+GKE +   +A    + V +S  + + +Q L + ++    T +  +  +H +  M+
Sbjct: 180  GLYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADV---FTVEEKAGRIHAVDHME 236

Query: 937  INFKGLQSHLKKCGGKYNQILAFRPTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSS 996
            I      S++ +    +  I     +   HS+              +  I+ IPYS+HSS
Sbjct: 237  I----CHSNMLRWNQTHPTIAILPTSRKIHSS--------------HPDIHVIPYSDHSS 278

Query: 997  YLEMKRFVQWLKPQKIIPTVN 1017
            Y E++ FV  LKP +++P V+
Sbjct: 279  YSELRAFVAALKPCQVVPIVS 299


>gi|76496497 artemis protein isoform a [Homo sapiens]
          Length = 692

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 101/336 (30%), Positives = 152/336 (45%), Gaps = 46/336 (13%)

Query: 727  AYFLTHFHSDHYAGLSK---------HFTFPVYCSEITGNLLKN--KLHVQEQYIHPLPL 775
            AYFL+H H DH  GL                +YCS +T  LL    K    ++ I  + +
Sbjct: 28   AYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEI 87

Query: 776  DTECIVNGVK----------VVLLDANHCPGAVMILFYLPNGTVILHTGDFR-ADPSMER 824
            +T   ++ V           V LL A HCPG+VM LF   NGTV L+TGDFR A     R
Sbjct: 88   ETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTV-LYTGDFRLAQGEAAR 146

Query: 825  SLLAD-----QKVHMLYLDTTYCSPE-YTFPSQQEVIRFAINTAFEAVTLNP-HALVVCG 877
              L       + +  +YLDTT+C P  Y  PS++E +   +      +T +P H + +  
Sbjct: 147  MELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNC 206

Query: 878  TYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEINSLITTDMCSSL---VHLLPM 934
              + G E +F  +++ LG +V ++    K     N+PEI   +TTD  + +    H    
Sbjct: 207  KAAYGYEYLFTNLSEELGVQVHVN----KLDMFRNMPEILHHLTTDRNTQIHACRHPKAE 262

Query: 935  MQINFKGLQSHLKKCGGKYNQILAFRPTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEH 994
                +  L   +         I++ +P+      + +R  +VI +T    S Y   +S H
Sbjct: 263  EYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGER-SRKTNVIVRT--GESSYRACFSFH 319

Query: 995  SSYLEMKRFVQWLKPQKIIPTV-NVGTWKSRSTMEK 1029
            SSY E+K F+ +L P    P V  VGT     TM+K
Sbjct: 320  SSYSEIKDFLSYLCPVNAYPNVIPVGT-----TMDK 350


>gi|76496501 artemis protein isoform c [Homo sapiens]
          Length = 572

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 72/243 (29%), Positives = 112/243 (46%), Gaps = 25/243 (10%)

Query: 799  MILFYLPNGTVILHTGDFR-ADPSMERSLLAD-----QKVHMLYLDTTYCSPE-YTFPSQ 851
            M LF   NGTV L+TGDFR A     R  L       + +  +YLDTT+C P  Y  PS+
Sbjct: 1    MFLFQGNNGTV-LYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSR 59

Query: 852  QEVIRFAINTAFEAVTLNPHALVVCGTYSI-GKEKVFLAIADVLGSKVGMSQEKYKTLQC 910
            +E +   +      +T +P+ +V     +  G E +F  +++ LG +V ++    K    
Sbjct: 60   EECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN----KLDMF 115

Query: 911  LNIPEINSLITTDMCSSLV---HLLPMMQINFKGLQSHLKKCGGKYNQILAFRPTGWTHS 967
             N+PEI   +TTD  + +    H        +  L   +         I++ +P+     
Sbjct: 116  RNMPEILHHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFG 175

Query: 968  NKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTV-NVGTWKSRST 1026
             + +R  +VI +T    S Y   +S HSSY E+K F+ +L P    P V  VGT     T
Sbjct: 176  ER-SRKTNVIVRT--GESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGT-----T 227

Query: 1027 MEK 1029
            M+K
Sbjct: 228  MDK 230


>gi|76496499 artemis protein isoform d [Homo sapiens]
          Length = 572

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 72/243 (29%), Positives = 112/243 (46%), Gaps = 25/243 (10%)

Query: 799  MILFYLPNGTVILHTGDFR-ADPSMERSLLAD-----QKVHMLYLDTTYCSPE-YTFPSQ 851
            M LF   NGTV L+TGDFR A     R  L       + +  +YLDTT+C P  Y  PS+
Sbjct: 1    MFLFQGNNGTV-LYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSR 59

Query: 852  QEVIRFAINTAFEAVTLNPHALVVCGTYSI-GKEKVFLAIADVLGSKVGMSQEKYKTLQC 910
            +E +   +      +T +P+ +V     +  G E +F  +++ LG +V ++    K    
Sbjct: 60   EECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN----KLDMF 115

Query: 911  LNIPEINSLITTDMCSSLV---HLLPMMQINFKGLQSHLKKCGGKYNQILAFRPTGWTHS 967
             N+PEI   +TTD  + +    H        +  L   +         I++ +P+     
Sbjct: 116  RNMPEILHHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFG 175

Query: 968  NKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTV-NVGTWKSRST 1026
             + +R  +VI +T    S Y   +S HSSY E+K F+ +L P    P V  VGT     T
Sbjct: 176  ER-SRKTNVIVRT--GESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGT-----T 227

Query: 1027 MEK 1029
            M+K
Sbjct: 228  MDK 230


>gi|76496495 artemis protein isoform b [Homo sapiens]
          Length = 577

 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 71/241 (29%), Positives = 111/241 (46%), Gaps = 25/241 (10%)

Query: 801  LFYLPNGTVILHTGDFR-ADPSMERSLLAD-----QKVHMLYLDTTYCSPE-YTFPSQQE 853
            LF   NGTV L+TGDFR A     R  L       + +  +YLDTT+C P  Y  PS++E
Sbjct: 8    LFQGNNGTV-LYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREE 66

Query: 854  VIRFAINTAFEAVTLNPHALVVCGTYSI-GKEKVFLAIADVLGSKVGMSQEKYKTLQCLN 912
             +   +      +T +P+ +V     +  G E +F  +++ LG +V ++    K     N
Sbjct: 67   CLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN----KLDMFRN 122

Query: 913  IPEINSLITTDMCSSLV---HLLPMMQINFKGLQSHLKKCGGKYNQILAFRPTGWTHSNK 969
            +PEI   +TTD  + +    H        +  L   +         I++ +P+      +
Sbjct: 123  MPEILHHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGER 182

Query: 970  FTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTV-NVGTWKSRSTME 1028
             +R  +VI +T    S Y   +S HSSY E+K F+ +L P    P V  VGT     TM+
Sbjct: 183  -SRKTNVIVRT--GESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGT-----TMD 234

Query: 1029 K 1029
            K
Sbjct: 235  K 235


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 37.7 bits (86), Expect = 0.057
 Identities = 56/299 (18%), Positives = 110/299 (36%), Gaps = 41/299 (13%)

Query: 412  PALAGKLAASVHQATKAKPDEPEFHSAQSN-----------KQKQVIEESSVYNQVSLPL 460
            P L+    +S  ++    P+  E    ++            + K + E S    Q+ +P 
Sbjct: 821  PLLSVPFLSSARRSVSGSPESDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPK 880

Query: 461  VKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATI 520
            V     K   S       SQP ++T+++++    N  N    +   R    G+P   +  
Sbjct: 881  VSKRATKKENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVS 940

Query: 521  --------------------LNTENLSSTPAPKYL--KILPSGLKYNARHPSTKVMKQMD 558
                                L T++++ TP  K +  ++L   +K  +  P        D
Sbjct: 941  AVDGLEDKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGP------D 994

Query: 559  IGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCKRKAEKSLSDLEFDASTLH 618
            IGV    P K  E  L     ++ ++ +   S +    SQ K ++ + +   + D S   
Sbjct: 995  IGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQR 1054

Query: 619  ESQLSVELSSERSQRQKKRCRKSNSLQEGAC--QKRSDHLINTESEAVNLSKVKVFTKS 675
            E+     + S +S          +  ++G+   +KRS + +++E  A   +  K   KS
Sbjct: 1055 ENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKS 1113


>gi|17505234 nucleolar and spindle associated protein 1 isoform 2
           [Homo sapiens]
          Length = 440

 Score = 37.4 bits (85), Expect = 0.074
 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 17/134 (12%)

Query: 262 TDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQE 321
           T+F  ++K     LR         +P P ++  + E + S    D         P + ++
Sbjct: 114 TEFQNHEKQESQDLRAT-----AKVPSPPDEHQEAENAVSSGNRDSKV------PSEGKK 162

Query: 322 QLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSL 381
            L+  ESSK G  +    +   FKK H    K+ +     ++ ++ R K  +     NS+
Sbjct: 163 SLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEME----SIDQYIERKK--KHFEEHNSM 216

Query: 382 NDLSQPISQNNEST 395
           N+L QPI++    T
Sbjct: 217 NELKQPINKGGVRT 230


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 37.4 bits (85), Expect = 0.074
 Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 28/141 (19%)

Query: 218 NQTDNSVSNDPLLMTQYFKKSPSLTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRL 277
           NQT    S  P+L +Q  +K+ S      K   H   ++  ++     ++D      +  
Sbjct: 547 NQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSD------IPS 600

Query: 278 ANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEED 337
           + +SE  N    E++  D E      + DE+  + DE  D   E    +ES  +GS EED
Sbjct: 601 SKDSEDSN----EDEEEDDE------EEDEEDDEDDESDDSQSESDSNSESDTEGSEEED 650

Query: 338 DDSCGFFKKRHGPLLKDQDES 358
           DD             KDQDES
Sbjct: 651 DDD------------KDQDES 659


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 36.6 bits (83), Expect = 0.13
 Identities = 22/107 (20%), Positives = 48/107 (44%)

Query: 3   EDISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEVKD 62
           E+  +ED+ +YK        D +    N+  S E+ ++ K  ++RSR++ R++ ++    
Sbjct: 157 EEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSR 216

Query: 63  HEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQH 109
              P  +     S + S +SS       ++++  + G   R+    H
Sbjct: 217 SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH 263


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 36.6 bits (83), Expect = 0.13
 Identities = 22/107 (20%), Positives = 48/107 (44%)

Query: 3   EDISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEVKD 62
           E+  +ED+ +YK        D +    N+  S E+ ++ K  ++RSR++ R++ ++    
Sbjct: 157 EEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSR 216

Query: 63  HEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQH 109
              P  +     S + S +SS       ++++  + G   R+    H
Sbjct: 217 SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH 263


>gi|67551265 transcription factor ELYS [Homo sapiens]
          Length = 2266

 Score = 35.8 bits (81), Expect = 0.22
 Identities = 49/250 (19%), Positives = 101/250 (40%), Gaps = 35/250 (14%)

Query: 451  SVYNQVSLPLVKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNNTNSACFCRKAL 510
            SV NQ S+ ++  L +    S              IRKL S NL+A  NT +    + + 
Sbjct: 1878 SVENQESVEIINDLKVSTVTSP----------SRMIRKLRSTNLDASENTGNKQDDKSSD 1927

Query: 511  EGVPVGKATILNTENLSSTPAPKYLKILPSGLKYNARHPSTKVMKQMDIGVYFGLPPKRK 570
            + + +     +    +S           PS ++ ++   S+++  Q +  +   +P KR 
Sbjct: 1928 KQLRIKHVRRVRGREVS-----------PSDVREDSNLESSQLTVQAEFDM-SAIPRKRG 1975

Query: 571  EEKLLGESALEGIN-LNPVPSPNQKRSSQCKRKAEKSL----SDLEFDASTLHES----- 620
              + +  S   G   +    SP +K +   +R++ ++      +++     L +S     
Sbjct: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPN 2035

Query: 621  -QLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLIN--TESEAVNLSKVKVFTKSAH 677
             +LS+ +SS++   +K   +          ++R+D + +  T  +   L     FTKS+ 
Sbjct: 2036 EELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSR 2095

Query: 678  GGLQRGNKKI 687
                R +K I
Sbjct: 2096 SSRTRSSKAI 2105


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 35.4 bits (80), Expect = 0.28
 Identities = 84/416 (20%), Positives = 159/416 (38%), Gaps = 44/416 (10%)

Query: 180  SRAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQYFKKSP 239
            S  GD  F SP  +S   F    + +  S E   SS ++  D ++    +  ++     P
Sbjct: 1349 SDEGDLQFPSPKISSSPKFDSRDNALSASNET--SSAEHLKDGTMKEMVVCSSESITCKP 1406

Query: 240  SLTEA--SEKISTHIQTSQQ-----------ALQFTDFVENDKLVGVALRLANNSEHINL 286
             L ++  S  + T     QQ           ++Q    +EN+   G AL L  N E    
Sbjct: 1407 QLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRY 1466

Query: 287  PLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKK 346
                 D         P  + E ++ + +K     E+L   +  +   L++ ++     + 
Sbjct: 1467 HCSGKD------QIVPSLNTESSNPVLKK----LEKLNTEKEERQKQLQQQNEKEMMEQI 1516

Query: 347  RHGPLLKDQDESCPKVNSFLTRDKYDEGLYR---FNSLNDLSQPISQNNESTLPYDLACT 403
            R    + +++    K    + + +  E L     + S   + +P S  + +T        
Sbjct: 1517 RQQTDILEKERKAFKT---IEKPRIGECLVAPSSYQSKQRVERPSSLLSLNTSNKGELNV 1573

Query: 404  GGDFVLFPPALAGKLAASVHQATKAKPDEPEFHSAQSNKQKQVIEESSVYNQVSLPLVKS 463
             G   L   ALA K ++S H   K +P    F    S  Q   ++E S  +++   L  +
Sbjct: 1574 LGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQL--N 1631

Query: 464  LMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNT 523
            +  K   +++      +PTQ+     +S++L+ + N     F  K    +P+     LN+
Sbjct: 1632 VACKLSNNRISKREHFRPTQSYSH--NSDDLSREGNARPIFFTPKDNMSIPLVSKEALNS 1689

Query: 524  EN----LSSTPAPKYLKILPSGLKYNARHPST-----KVMKQMDIGVYFGLPPKRK 570
            +N        PA K +K+   G +  ++  S+     K+ K M  G    L  ++K
Sbjct: 1690 KNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQAKLHKTMSQGEITKLAVRQK 1745


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 35.4 bits (80), Expect = 0.28
 Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 8/87 (9%)

Query: 588 VPSPNQKRSSQCKRKAEKSLSDLEFDASTLHESQLSVELSS------ERSQRQKKRCRKS 641
           +P    K+  + + K+  S S    D+ +  +SQ S + S       E+S+++KK+ RK+
Sbjct: 178 IPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKN 237

Query: 642 N--SLQEGACQKRSDHLINTESEAVNL 666
           +    +E   +K+S    ++ESEA NL
Sbjct: 238 SRKHKKEKKKRKKSKKSASSESEAENL 264



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 5/81 (6%)

Query: 6   SEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKY---QSKRSRNRKRAAEAKEVKD 62
           SE+D  +YK+K K KR    + SK+  KS  K  D K+   + KR R+R +  + + VK+
Sbjct: 442 SEKDD-KYKNKVK-KRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE 499

Query: 63  HEVPLGNAGCQTSVASSQNSS 83
            E    + G     + S+  S
Sbjct: 500 KEKQSDSKGKDQERSRSKEKS 520


>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
           sapiens]
          Length = 1108

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 43/216 (19%)

Query: 411 PPALAGKLAASVHQAT---KAKPDEPEFHSAQS--------NKQKQVIEESSVYNQVSLP 459
           P A A K  +SV  AT      P +P   +  S        N Q    E S + + V+LP
Sbjct: 546 PAAEAEKPESSVSSATGDGNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLP 605

Query: 460 LVKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNN-----------TNSACFCRK 508
           L   ++ K FE    G +S Q ++ +  +    N+ AKNN            +S    + 
Sbjct: 606 L--DVVKKWFEKMQAGQISVQSSEPSSPEPGKVNIPAKNNDQPQSANANEPQDSTVNLQS 663

Query: 509 ALE-----GVPVGKATILNTENLSSTPAPKYLKILPS----GLKYNARHPSTK-VMKQMD 558
            L+      +PVG  T     + SSTP+P  L +  S    G  Y A     +  ++ +D
Sbjct: 664 PLKMTNSPVLPVGSTT---NGSRSSTPSPSPLNLSSSRNTQGYLYTAEGAQEEPQVEPLD 720

Query: 559 IGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQK 594
           + +     PK++ E LL  S +  +  N V S  ++
Sbjct: 721 LSL-----PKQQGE-LLERSTITSVYQNSVYSVQEE 750


>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
           sapiens]
          Length = 1124

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 43/216 (19%)

Query: 411 PPALAGKLAASVHQAT---KAKPDEPEFHSAQS--------NKQKQVIEESSVYNQVSLP 459
           P A A K  +SV  AT      P +P   +  S        N Q    E S + + V+LP
Sbjct: 562 PAAEAEKPESSVSSATGDGNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLP 621

Query: 460 LVKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNN-----------TNSACFCRK 508
           L   ++ K FE    G +S Q ++ +  +    N+ AKNN            +S    + 
Sbjct: 622 L--DVVKKWFEKMQAGQISVQSSEPSSPEPGKVNIPAKNNDQPQSANANEPQDSTVNLQS 679

Query: 509 ALE-----GVPVGKATILNTENLSSTPAPKYLKILPS----GLKYNARHPSTK-VMKQMD 558
            L+      +PVG  T     + SSTP+P  L +  S    G  Y A     +  ++ +D
Sbjct: 680 PLKMTNSPVLPVGSTT---NGSRSSTPSPSPLNLSSSRNTQGYLYTAEGAQEEPQVEPLD 736

Query: 559 IGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQK 594
           + +     PK++ E LL  S +  +  N V S  ++
Sbjct: 737 LSL-----PKQQGE-LLERSTITSVYQNSVYSVQEE 766


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 139/756 (18%), Positives = 254/756 (33%), Gaps = 115/756 (15%)

Query: 6   SEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKR---------AAE 56
           S +D++E K ++KP   + ++ S N   S E +++ + + +RSR RK             
Sbjct: 180 SIKDVFE-KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKR 238

Query: 57  AKEVKDHEVPLG---------NAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCR---- 103
            KE    E P           +    T+   S +SS        + +E  P    R    
Sbjct: 239 RKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLR 298

Query: 104 ------TQKSQHVSPKIRPVYDGYCPNCQMPFSSLIGQ-TPRWHVFECLDSPPRSETECP 156
                 T + +   P + P+     P+       + G+ T R+H      +PPRS +   
Sbjct: 299 RDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYH------TPPRSRSCSE 352

Query: 157 DGLLCTSTIPFHYKRYTHFLLAQSRAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSY 216
                +S  P H+K     L A        +S     S    S      L      WS  
Sbjct: 353 SDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYN 412

Query: 217 QNQTDNSVSNDPLLMTQYFKKSPSLTEASEK--------ISTHIQTSQQALQFTDFVEND 268
              +D S +      + + KK     +   K           H QT ++ +     +E+ 
Sbjct: 413 GYYSDLSTARH----SGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESS 468

Query: 269 KLVGVALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDI---DEKPDDSQEQLFF 325
           K     ++                 S C+   S   S   +H     D    D   Q   
Sbjct: 469 KSSTRRMK-----------------SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSL 511

Query: 326 TESSKDGSLEEDDD---SCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSLN 382
           T SS+D    +      S G  + R          S  K  S     K         S  
Sbjct: 512 THSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRS---SSKSGHRKRASKSPR 568

Query: 383 DLSQPISQNNE-STLPYDLACTGGDFVLFPPALAGKLAA--------SVHQATKAKPDEP 433
             +  +S+N    T P        + V+  P +A  +                  KP +P
Sbjct: 569 KTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKP 628

Query: 434 EFHSAQSNKQK--QVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQPTQNTIRKLSS 491
            +   Q  K K   ++   S Y+  ++    S       S  +   +S+  Q+T  K S 
Sbjct: 629 SYERIQEMKAKTTHLLPIQSTYSLANIKETGS-----SSSYHKREKNSESDQSTYSKYSD 683

Query: 492 ENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPSGLKYNARHPST 551
            +  +   + S     ++         ++ ++ + S +P+ +      S  KY+     +
Sbjct: 684 RSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSR----SHSRNKYSDHSQCS 739

Query: 552 KVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKR----------SSQCKR 601
           +      I    G   +R + +L        ++     S ++K            S C R
Sbjct: 740 RSSSYTSISSDDG---RRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVR 796

Query: 602 KAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLINTES 661
           K  +S S L++ +S   +S +    S++  ++Q +  R  N  ++   +++S     +E 
Sbjct: 797 KYSESRSSLDY-SSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKS----KSER 851

Query: 662 EAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSR 697
           E  + SK +   ++    L+ G+K  P+  N  GS+
Sbjct: 852 ECPH-SKKRTLKENLSDHLRNGSK--PKRKNYAGSK 884


>gi|148747556 PIN2-interacting protein 1 [Homo sapiens]
          Length = 328

 Score = 34.3 bits (77), Expect = 0.63
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 4   DISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEVKDH 63
           DISE  +   + K++ K     +    +    ++ T+GK   +R+  ++R A+ K     
Sbjct: 201 DISETQVERKRGKKRNKEATGKDVESYLQPKAKRHTEGK--PERAEAQERVAKKKSAPAE 258

Query: 64  EVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETT 97
           E   G    Q+S AS+Q++  GD +Q  + ++ T
Sbjct: 259 EQLRGPCWDQSSKASAQDA--GDHVQPPEGRDFT 290


>gi|239755261 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 133

 Score = 34.3 bits (77), Expect = 0.63
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 832 VHMLYLDTTYCSPE-YTFPSQQEVIRFAINTAFEAVTLN-PHALVVCGTYSIGKEKVFLA 889
           +  +YLDT  C P  Y  PSQ+E +   +      +T +  H + +    + G E +F  
Sbjct: 29  IQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFTN 88

Query: 890 IADVLGSKVGMSQEKYKTLQCLNIPEINSLITTD 923
           +++ LG ++ ++    K     N+PEI   +TTD
Sbjct: 89  LSEELGVQIHVN----KLDMFRNMPEILHHLTTD 118


>gi|239749742 PREDICTED: hypothetical protein XP_002347147 [Homo
           sapiens]
          Length = 133

 Score = 34.3 bits (77), Expect = 0.63
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 832 VHMLYLDTTYCSPE-YTFPSQQEVIRFAINTAFEAVTLN-PHALVVCGTYSIGKEKVFLA 889
           +  +YLDT  C P  Y  PSQ+E +   +      +T +  H + +    + G E +F  
Sbjct: 29  IQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFTN 88

Query: 890 IADVLGSKVGMSQEKYKTLQCLNIPEINSLITTD 923
           +++ LG ++ ++    K     N+PEI   +TTD
Sbjct: 89  LSEELGVQIHVN----KLDMFRNMPEILHHLTTD 118


>gi|239743997 PREDICTED: hypothetical protein XP_002343013 [Homo
           sapiens]
          Length = 133

 Score = 34.3 bits (77), Expect = 0.63
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 832 VHMLYLDTTYCSPE-YTFPSQQEVIRFAINTAFEAVTLN-PHALVVCGTYSIGKEKVFLA 889
           +  +YLDT  C P  Y  PSQ+E +   +      +T +  H + +    + G E +F  
Sbjct: 29  IQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFTN 88

Query: 890 IADVLGSKVGMSQEKYKTLQCLNIPEINSLITTD 923
           +++ LG ++ ++    K     N+PEI   +TTD
Sbjct: 89  LSEELGVQIHVN----KLDMFRNMPEILHHLTTD 118


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 34.3 bits (77), Expect = 0.63
 Identities = 44/214 (20%), Positives = 91/214 (42%), Gaps = 24/214 (11%)

Query: 178  AQSRAGDHPFSSPSPASGGSF---SETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQY 234
            A+ +  DH  +    A G      +ET S V+    E  SS + Q +N + +   L+ + 
Sbjct: 2299 AEVQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQEMQVENELED---LIDEL 2355

Query: 235  FKKSPSLTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINL--PLPEND 292
             ++      ++  +S   +   Q     D   ++      L+ AN  + +N+  P  E +
Sbjct: 2356 LERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQ-ANREDSMNILDPEDEEE 2414

Query: 293  FSDCEISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLL 352
             +  E S    + ++D+ D +E+ ++ +E     +  ++G  +EDDD  G          
Sbjct: 2415 HTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEG--DEDDDDDG--------SE 2464

Query: 353  KDQDESCPKVNS-----FLTRDKYDEGLYRFNSL 381
             + DE  P +N+     F   D+ D+ +  F+++
Sbjct: 2465 MELDEDYPDMNASPLVRFERFDREDDLIIEFDNM 2498


>gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]
          Length = 379

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 19/115 (16%)

Query: 585 LNPVPSPNQKRSSQCKRKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSL 644
           L+PV +P+ + S++      K   +         + ++       + +RQKKR R+   L
Sbjct: 155 LHPVANPHAEISTKVPASKVKDAVE--------QQGEVKKNKRERKEERQKKRKREKKEL 206

Query: 645 QEGACQKRSDHLINTESEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKK 699
                 K  +H  N+ ++     K K   K     L+ G +++PE++   G R K
Sbjct: 207 ------KLENHQENSRNQ-----KPKKRKKGQEADLEAGGEEVPEANGSAGKRSK 250


>gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]
          Length = 379

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 19/115 (16%)

Query: 585 LNPVPSPNQKRSSQCKRKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSL 644
           L+PV +P+ + S++      K   +         + ++       + +RQKKR R+   L
Sbjct: 155 LHPVANPHAEISTKVPASKVKDAVE--------QQGEVKKNKRERKEERQKKRKREKKEL 206

Query: 645 QEGACQKRSDHLINTESEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKK 699
                 K  +H  N+ ++     K K   K     L+ G +++PE++   G R K
Sbjct: 207 ------KLENHQENSRNQ-----KPKKRKKGQEADLEAGGEEVPEANGSAGKRSK 250


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 33.1 bits (74), Expect = 1.4
 Identities = 46/217 (21%), Positives = 80/217 (36%), Gaps = 10/217 (4%)

Query: 180 SRAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQYFKKSP 239
           S  GD  ++S      G+ S++K G      +  S   N   N   N+            
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSK-GAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544

Query: 240 SLTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEIS 299
             +++S+  S+    S  +   +D   +D          ++S+  +     +D SD + S
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDS--------NSSSDSDSSDSDSSDSSDSDSS 596

Query: 300 YSPLQSDE-DTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDES 358
            S   SD  D+ D  +  D S      ++SSK  S   D DS       +     D  +S
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656

Query: 359 CPKVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNEST 395
               NS  + D  D      +S +  S   S +++S+
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 33.1 bits (74), Expect = 1.4
 Identities = 59/259 (22%), Positives = 100/259 (38%), Gaps = 30/259 (11%)

Query: 241  LTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINLPLP---ENDFSDCE 297
            +T  S K+S+  ++  +  Q     ++  L    +R+   S     PLP   +++ S  E
Sbjct: 2653 VTSESRKVSSSSESEPELAQLKKGADSGLLPEPVIRVQPPS-----PLPSSMDSNSSPEE 2707

Query: 298  ISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDE 357
            + + P+ S + T  ++E   D+QE+   +E  KD      +D       RH    + +D 
Sbjct: 2708 VQFQPVVSKQYTFKMNE---DTQEEPGKSEEEKDSESHLAED-------RHAVSTEAEDR 2757

Query: 358  SCPKVNSFLTRDKYDEGL-YRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPALAG 416
            S  K+N    + K  +G      S +  + P+S   +S        TG D    P     
Sbjct: 2758 SYDKLNRDTDQPKICDGHGCEAMSPSSSAAPVSSGLQSP-------TGDDVDEQPVIYKE 2810

Query: 417  KLAASVHQATKAKPDE-PEFHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEG 475
             LA    Q T  K  E  E   +++   +      S  +  SLP       K  +  +  
Sbjct: 2811 SLAL---QGTHEKDTEGEELDVSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISA 2867

Query: 476  YLSSQPTQNTIRKLSSENL 494
              S Q T+ T    + ENL
Sbjct: 2868 TSSIQKTEVTKTDETFENL 2886


>gi|193804867 nucleolar and spindle associated protein 1 isoform 3
           [Homo sapiens]
          Length = 402

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 18/135 (13%)

Query: 262 TDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQE 321
           T+F  ++K     LR         +P P ++  + E + S    D         P + ++
Sbjct: 114 TEFQNHEKQESQDLRAT-----AKVPSPPDEHQEAENAVSSGNRDSKV------PSEGKK 162

Query: 322 QLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSL 381
            L+  ESSK G  +    +   FKK H    K+ +     ++ ++ R K  +     NS+
Sbjct: 163 SLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEME----SIDQYIERKK--KHFEEHNSM 216

Query: 382 NDL-SQPISQNNEST 395
           N+L  QPI++    T
Sbjct: 217 NELKQQPINKGGVRT 231


>gi|193804865 nucleolar and spindle associated protein 1 isoform 1
           [Homo sapiens]
          Length = 441

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 18/135 (13%)

Query: 262 TDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQE 321
           T+F  ++K     LR         +P P ++  + E + S    D         P + ++
Sbjct: 114 TEFQNHEKQESQDLRAT-----AKVPSPPDEHQEAENAVSSGNRDSKV------PSEGKK 162

Query: 322 QLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSL 381
            L+  ESSK G  +    +   FKK H    K+ +     ++ ++ R K  +     NS+
Sbjct: 163 SLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEME----SIDQYIERKK--KHFEEHNSM 216

Query: 382 NDL-SQPISQNNEST 395
           N+L  QPI++    T
Sbjct: 217 NELKQQPINKGGVRT 231


>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 9 [Homo sapiens]
          Length = 684

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 24/109 (22%), Positives = 44/109 (40%), Gaps = 17/109 (15%)

Query: 576 GESALEGINLNPVPSPNQKRSSQCKRKAEKSL-------SDLEFDASTLHESQLSVELSS 628
           G S+     LNP PSP+  +    K+K+  +            F+A+T  E    V+   
Sbjct: 380 GISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQ 439

Query: 629 ERSQRQKKRCRKSNSLQEGACQKRSDHLINTESEAVNLSKVKVFTKSAH 677
            +     + C+ S S  +          + ++SEA+ L  ++    +AH
Sbjct: 440 SQILASLQSCKSSKSKSQ----------LTSQSEAMALQSIQNMRGNAH 478


>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 10 [Homo sapiens]
          Length = 684

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 24/109 (22%), Positives = 44/109 (40%), Gaps = 17/109 (15%)

Query: 576 GESALEGINLNPVPSPNQKRSSQCKRKAEKSL-------SDLEFDASTLHESQLSVELSS 628
           G S+     LNP PSP+  +    K+K+  +            F+A+T  E    V+   
Sbjct: 380 GISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQ 439

Query: 629 ERSQRQKKRCRKSNSLQEGACQKRSDHLINTESEAVNLSKVKVFTKSAH 677
            +     + C+ S S  +          + ++SEA+ L  ++    +AH
Sbjct: 440 SQILASLQSCKSSKSKSQ----------LTSQSEAMALQSIQNMRGNAH 478


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,938,511
Number of Sequences: 37866
Number of extensions: 1994375
Number of successful extensions: 5170
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 5056
Number of HSP's gapped (non-prelim): 148
length of query: 1040
length of database: 18,247,518
effective HSP length: 112
effective length of query: 928
effective length of database: 14,006,526
effective search space: 12998056128
effective search space used: 12998056128
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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