Search of human proteins with 223005859

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
         (1066 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]            2138   0.0  
gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens]            1769   0.0  
gi|148746195 trichohyalin [Homo sapiens]                               81   6e-15
gi|219803769 trichoplein [Homo sapiens]                                71   6e-12
gi|14150056 trichoplein [Homo sapiens]                                 71   6e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    70   8e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    68   4e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    67   1e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    67   1e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    67   1e-10
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    67   1e-10
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    67   1e-10
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    66   2e-10
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]      62   3e-09
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    62   3e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    62   4e-09
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]          62   4e-09
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                61   5e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    61   6e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    60   8e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                60   1e-08
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                60   1e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       60   1e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    59   3e-08
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]          59   3e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    58   4e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    58   4e-08
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    58   4e-08
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        58   4e-08
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        58   4e-08

>gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
          Length = 1066

 Score = 2138 bits (5539), Expect = 0.0
 Identities = 1066/1066 (100%), Positives = 1066/1066 (100%)

Query: 1    MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60
            MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG
Sbjct: 1    MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60

Query: 61   DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120
            DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS
Sbjct: 61   DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120

Query: 121  WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180
            WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS
Sbjct: 121  WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180

Query: 181  NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240
            NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL
Sbjct: 181  NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240

Query: 241  WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300
            WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF
Sbjct: 241  WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300

Query: 301  EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360
            EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK
Sbjct: 301  EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360

Query: 361  LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420
            LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK
Sbjct: 361  LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420

Query: 421  GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480
            GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT
Sbjct: 421  GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480

Query: 481  LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540
            LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN
Sbjct: 481  LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540

Query: 541  ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600
            ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP
Sbjct: 541  ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600

Query: 601  SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660
            SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD
Sbjct: 601  SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660

Query: 661  SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720
            SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR
Sbjct: 661  SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720

Query: 721  VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780
            VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF
Sbjct: 721  VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780

Query: 781  LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQE 840
            LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQE
Sbjct: 781  LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQE 840

Query: 841  ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
            ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI
Sbjct: 841  ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900

Query: 901  QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960
            QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK
Sbjct: 901  QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960

Query: 961  KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPS 1020
            KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPS
Sbjct: 961  KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPS 1020

Query: 1021 TQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066
            TQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA
Sbjct: 1021 TQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066


>gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens]
          Length = 970

 Score = 1769 bits (4583), Expect = 0.0
 Identities = 923/1068 (86%), Positives = 935/1068 (87%), Gaps = 100/1068 (9%)

Query: 1    MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60
            MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG
Sbjct: 1    MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60

Query: 61   DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120
            DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS
Sbjct: 61   DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120

Query: 121  WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180
            WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS
Sbjct: 121  WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180

Query: 181  NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240
            NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL
Sbjct: 181  NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240

Query: 241  WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300
            WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF
Sbjct: 241  WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300

Query: 301  EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360
            EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK
Sbjct: 301  EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360

Query: 361  LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420
            LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK
Sbjct: 361  LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420

Query: 421  GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480
            GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT
Sbjct: 421  GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480

Query: 481  LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540
            LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN
Sbjct: 481  LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540

Query: 541  ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600
            ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP
Sbjct: 541  ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600

Query: 601  SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660
            SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD
Sbjct: 601  SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660

Query: 661  SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720
            SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR
Sbjct: 661  SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720

Query: 721  VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780
            VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF
Sbjct: 721  VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780

Query: 781  LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQE 840
            LKLQQDQQEMELRRLDDEIGR                               KNLTENQE
Sbjct: 781  LKLQQDQQEMELRRLDDEIGR-------------------------------KNLTENQE 809

Query: 841  ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
            ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK  KE   K        ++++
Sbjct: 810  ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK-WKEAEGK--------EFRL 860

Query: 901  QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEI--EIINAMVEEEAKKWKEAEGKEFRLRS 958
            +S  K               A  L +  RK    + INA VE           +E R ++
Sbjct: 861  RSAKK---------------ASALSDASRKWFLKQEINAAVEHAE---NPCHKEEPRFQN 902

Query: 959  AKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMD 1018
             + +S L                            PR     DS            SEMD
Sbjct: 903  EQDSSCL----------------------------PRTSQLNDS------------SEMD 922

Query: 1019 PSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066
            PSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA
Sbjct: 923  PSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 970


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 83/331 (25%), Positives = 150/331 (45%), Gaps = 32/331 (9%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQ-----RVEDEAWYQK----QELLRKAEETR 740
            +E E+++ +E    RE Q  E+   K+++Q     R E+E   Q+    Q+L RK EE R
Sbjct: 255  KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314

Query: 741  REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ--EMELRRLDDE 798
            RE   QEE +  Q+R+     +RE +++    Q+  R + L+ +Q+++  E +LRR  +E
Sbjct: 315  REQ--QEERREQQERREQQEERREQQLRRE--QEERREQQLRREQEEERREQQLRREQEE 370

Query: 799  IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVD 858
              R+  +R  +     + L   Q     Q+   E+ L   Q+   ++        RR+ +
Sbjct: 371  ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430

Query: 859  LEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQ 918
             E H      E  E + ++ Q+  ++ L + E+    T+   Q   KQ+    Q  +  +
Sbjct: 431  EERHEQKHEQERREQRLKREQEERRDWLKREEE----TERHEQERRKQQLKRDQEEERRE 486

Query: 919  EVAKLLRENRRKEIEIINAMV--------EEEAKKWKEAEGKEFRLRSAKKASALSDASR 970
               KL  E RR++ E     +        E+  K+ +E E  + RLRS ++     +  R
Sbjct: 487  RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546

Query: 971  KWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
            +  LK+E    +E       + E R + EQ+
Sbjct: 547  EQLLKREEEKRLEQ-----ERREQRLKREQE 572



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 65/344 (18%), Positives = 154/344 (44%), Gaps = 34/344 (9%)

Query: 686 DYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL 745
           + + +  +++R ++ +  RE+Q   + + +  +Q++  E   ++++ LR+ ++ RRE  L
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401

Query: 746 QEE-----------EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD-----QQE 789
           + E           E+ +++ Q+L   + E + ++ H Q+   +R  + Q++     ++E
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461

Query: 790 MELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNL-------------- 835
            E  R + E  ++   RD+E     R L++ + E   Q+   E+ L              
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521

Query: 836 TENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLN 895
            E +E L + +R++    R + +  E +  +  E    Q ++ Q++ +E   + +Q    
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581

Query: 896 TDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKK--WKEAEGKE 953
            + + Q   K++ ++    +  +E  + L +  R+E  +     EEE ++   K  E +E
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641

Query: 954 FRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQ 997
            R +  ++     +   +   ++E    +E      H+EE R Q
Sbjct: 642 RRQQQLRREQ--QERREQRLKREEEEERLEQRLKREHEEERREQ 683



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 76/326 (23%), Positives = 142/326 (43%), Gaps = 25/326 (7%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQ-----RVEDEAWYQKQELLRKAEETRREMLL 745
            + E++R  EL  LR +   E  Q + ++Q       E++ W +++ +LRK EE      L
Sbjct: 206  DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK-----L 260

Query: 746  QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYM 805
            QEEE    QRQR    + E +++++  Q+  R R    Q+++Q+ +  R + ++ RK   
Sbjct: 261  QEEE---PQRQR-ELQEEEEQLRKLERQELRRER----QEEEQQQQRLRREQQLRRKQEE 312

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNL-TENQEALAKEMRADADAYRRKVDLEEHMF 864
              RE     R+ + R+   E Q+   E+ L  E +E   +++R + +  RR+  L     
Sbjct: 313  ERREQQEERREQQERR---EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369

Query: 865  HKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLL 924
                E  E Q ++ Q++ +E   + EQ         +    ++   L+R +  +   +L 
Sbjct: 370  E---ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426

Query: 925  RENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEH 984
            RE   +  E  +     E +  +E E +   L+  ++        RK  LK++       
Sbjct: 427  REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486

Query: 985  AENPCHKEEPRFQNEQDSSCLPRTSQ 1010
                  +EE R Q E+    L R  +
Sbjct: 487  RWLKLEEEERREQQERREQQLRREQE 512



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 93/394 (23%), Positives = 167/394 (42%), Gaps = 39/394 (9%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWY-----QKQELLRKAEETRREML 744
            QE ER         RE++   + + + D  + E+E        +KQ+L R  EE RRE  
Sbjct: 429  QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488

Query: 745  L---QEEEKMIQQR--QRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEI 799
            L   +EE +  Q+R  Q+L   + E + + +  Q+   R   +L+ +QQ   LRR  +E 
Sbjct: 489  LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ---LRREQEER 545

Query: 800  GRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAK---EMRADADAYRRK 856
              ++  R+ E          ++LE E +++  ++   E ++ L K   E R       ++
Sbjct: 546  REQLLKREEE----------KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595

Query: 857  VDLEEHMFHKLIEAGETQSQKTQKVIKEN-LAKAEQACLNTDWQIQSLHKQKCDDLQRNK 915
              LE+ +  + +E  E + ++ Q++ +E    +  Q  L ++ Q +   +Q    L+R +
Sbjct: 596  ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ----LRREQ 651

Query: 916  CYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLK 975
              +   +L RE   + +E    +  E  ++ +E E  E     A++         +W L+
Sbjct: 652  QERREQRLKREEEEERLE--QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709

Query: 976  QEINAAVEHA-ENPCHKEEPRFQNEQDSSCLPRTSQL--NDSSEMDPSTQISLNRRAVEW 1032
             E +A        P  +E  R + EQ+     R S+L   +        Q    RR   W
Sbjct: 710  SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW 769

Query: 1033 DTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066
                +   +K    RQRL+AR   R Q    L A
Sbjct: 770  QWQAE---EKSERGRQRLSARPPLREQRERQLRA 800



 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 79/387 (20%), Positives = 168/387 (43%), Gaps = 31/387 (8%)

Query: 688  QTQERERIRNDE-LDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQ 746
            + Q+++R+R ++ L   +E +  E  + + +QQ   ++   ++++ LR+ +E RRE  L+
Sbjct: 293  EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352

Query: 747  EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ---EMELR-----RLDDE 798
             E++  ++ Q+L   + E + ++   ++   RR  +L+++QQ   E +LR     R + +
Sbjct: 353  REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412

Query: 799  IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRR--- 855
            + R+  +R  +     ++ E  + + E ++R  E+ L   QE     ++ + +  R    
Sbjct: 413  LRREQQLRREQQLRREQEEERHEQKHEQERR--EQRLKREQEERRDWLKREEETERHEQE 470

Query: 856  ------KVDLEEHMFHKLI-----EAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLH 904
                  K D EE    + +     E  E Q ++ Q++ +E   + EQ     + + +   
Sbjct: 471  RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530

Query: 905  KQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASA 964
            + + +   R +  +   +LL+    K +E      E+  K+ +E    +   R  ++   
Sbjct: 531  RLRSEQQLRREQEERREQLLKREEEKRLE--QERREQRLKREQEERRDQLLKREEERRQQ 588

Query: 965  LSDASRKWFLKQEI-NAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQI 1023
                 ++  L+Q +    VE  E    + E R + E+      R  QL  S E +   Q 
Sbjct: 589  RLKREQEERLEQRLKREEVERLEQE-ERREQRLKREEPEE--ERRQQLLKSEEQEERRQQ 645

Query: 1024 SLNRRAVEWDTTGQNLIKKVRNLRQRL 1050
             L R   E         ++   L QRL
Sbjct: 646  QLRREQQERREQRLKREEEEERLEQRL 672



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 84/393 (21%), Positives = 166/393 (42%), Gaps = 44/393 (11%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR------ 741
            Q ++++ ++ +E   LRE +    +Q +  Q R E+E   ++++LL +  ETRR      
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078

Query: 742  -----EMLLQEEEKMI---------QQRQRLAAVKRELKVKEMHL--QDAARRRFLKLQQ 785
                 E L QEEE+++         Q+R+R    + EL+ +E  L  ++  +RR  +L++
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138

Query: 786  DQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKE 845
              +E E  + ++E      +R+       ++LE +  E E  ++  E+ L E QE   +E
Sbjct: 1139 QYREEEEVQQEEE----QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194

Query: 846  MRADADAYRRKVDLEEHMFHKLIEAGETQSQ-KTQKVIKENLAKAEQACLNTDWQIQSLH 904
                   YR + +L+     +     + +S  K Q   ++  A  +        + +   
Sbjct: 1195 RERQ---YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251

Query: 905  KQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASA 964
            + +   L+  +  Q++  LL E + ++        E+E ++W++ + + F      +   
Sbjct: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERD-------REQERRRWQQRD-RHFPEEEQLEREE 1303

Query: 965  LSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQIS 1024
              +A R+    QE    +        +EE R + E D        QL    E  P  +  
Sbjct: 1304 QKEAKRRDRKSQEEKQLLRE-----EREEKRRRQETDRK-FREEEQLLQEREEQPLRRQE 1357

Query: 1025 LNRRAVEWDTTGQNLIKKVRNLRQRLTARARHR 1057
             +R+  E +   Q   +K     QRL  + R R
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQERER 1390



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 91/418 (21%), Positives = 174/418 (41%), Gaps = 68/418 (16%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELL----RKAEE----- 738
            Q QERE    +E    +ER    D      +QR ++E W Q+QE      R+AEE     
Sbjct: 142  QEQERELAEGEEQSEKQERLEQRD------RQRRDEELWRQRQEWQEREERRAEEEQLQS 195

Query: 739  --------------TRREMLLQ-----EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR 779
                           RR  LL+      EEK  Q+R+R   V +E + KE   ++   R+
Sbjct: 196  CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255

Query: 780  FLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTE-- 837
              +  Q+++    R L +E  +   +  +E+    ++ E +Q  L  +++L  K   E  
Sbjct: 256  EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315

Query: 838  --NQEALAKEMRADADAYRRKVDL---EEHMFHKLIEAGETQSQKTQKVIKENLAKAEQA 892
               +E   ++ R +    RR+  L   +E    + +   + + ++ Q++ +E   +  + 
Sbjct: 316  EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375

Query: 893  CLNTDWQI---QSLHKQ----KCDDLQRNKCYQEVAKLLRENR-RKEIEIINAMVEEEAK 944
             L  + Q+   Q L ++    +   L+R +  +   +L RE + R+E ++     EE  +
Sbjct: 376  QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435

Query: 945  KWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQ---NEQD 1001
            +  E E +E RL+  +      +  R W  ++E        E   H++E R Q    +Q+
Sbjct: 436  QKHEQERREQRLKREQ------EERRDWLKREE--------ETERHEQERRKQQLKRDQE 481

Query: 1002 SSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIK--KVRNLRQRLTARARHR 1057
                 R  +L +    +   +     R  + +   Q L +  +   L+QRL +  + R
Sbjct: 482  EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 83/345 (24%), Positives = 152/345 (44%), Gaps = 49/345 (14%)

Query: 688  QTQERERIRN--DELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKA--------- 736
            Q Q RER +   +E D L+E     D + +  Q++  D+ W  + E  RK          
Sbjct: 839  QLQRRERAQQLQEEEDGLQE-----DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP 893

Query: 737  ---EETRREM-LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
               E+ R+E  LLQEEE+ +Q+ +R    KR  + +E   ++  + +  + Q  ++E E 
Sbjct: 894  ALQEQLRKEQQLLQEEEEELQREER---EKRRRQEQERQYREEEQLQQEEEQLLREEREK 950

Query: 793  RRLDDEIGRKVYMRDREIAATARDL-----EMRQLELESQKRLYEKNLTENQEALAKEMR 847
            RR  +    + Y +D+++      L     E R+ +   +K   E+ L + +E L +E R
Sbjct: 951  RRRQER--ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008

Query: 848  AD------ADAYRRKVDL---EEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDW 898
                       YR+K +L   EE +  +  E    Q ++ Q   +E L + E+  L  + 
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068

Query: 899  QIQSLHKQKCDDLQRNKCYQEVAKLLRE--NRRKEIEIINAMVEEEAKKWKEAEGKEFRL 956
            + +   + +    +  +  QE  +LLRE   +R+  E      EEE  + +E    E  L
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE----EQLL 1124

Query: 957  RSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
            R  ++     +  R++  ++E    V+  E    +EEP  +  Q+
Sbjct: 1125 REEREKRRRQELERQYREEEE----VQQEEEQLLREEPEKRRRQE 1165



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 72/349 (20%), Positives = 157/349 (44%), Gaps = 48/349 (13%)

Query: 692 RERIRND-----ELDYLRERQTVEDMQAKVDQ----QRVEDEAWYQKQELLRKAEETRRE 742
           ++R+R++     E +  RE+    + + +++Q    QR++ E   ++ +LL++ EE R++
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588

Query: 743 MLLQEEEKMIQQRQRLAAV-------KRELKVKEMHLQDAARRRFLKL--QQDQQEMELR 793
            L +E+E+ ++QR +   V       +RE ++K    ++  R++ LK   Q+++++ +LR
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648

Query: 794 RLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKE-------- 845
           R   E   +   R+ E       LE R L+ E ++   E+ L E ++  A+E        
Sbjct: 649 REQQERREQRLKREEE----EERLEQR-LKREHEEERREQELAEEEQEQARERIKSRIPK 703

Query: 846 ----MRADADAYRRKV-----------DLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
               + ++ADA + KV             +E    +     E Q Q+ ++  ++   + +
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763

Query: 891 QACLNTDWQIQSLHKQKCDDLQRNKCYQE--VAKLLRENRRKEIEIINAMVEEEAKKWKE 948
           +      WQ +   ++    L      +E    +L  E R++  +      EE+ ++ ++
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823

Query: 949 AEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQ 997
              +E  L+  ++   L    R   L++E +   E  E    +E+ R Q
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 76/340 (22%), Positives = 147/340 (43%), Gaps = 32/340 (9%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVED-----EAWYQK------QELLRKAEE 738
            +E E+ R  E   LR+RQ+ +D+Q  + +Q+  D       W Q+      +E L + E+
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304

Query: 739  ---TRREMLLQEEEKMI----QQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME 791
                RR+   QEE++++    ++++R     R+ + +E  LQ+   +   + ++D++  E
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364

Query: 792  LRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADAD 851
                  E GRK    ++ +    R  E + L+ E Q R  E+     Q+   K    +  
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQER--ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422

Query: 852  AYRRKVD---LEEHMFHKLIEAGETQSQKTQKVIKENLAK-AEQACLNTDWQIQSLHKQK 907
              R++ D    EE    +  E      ++ Q++ +E   K  E+  L  + + Q LH+Q+
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482

Query: 908  CDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSD 967
             D     K  +E  +L R+ R ++        +E  +K+ E E +  R +  +K      
Sbjct: 1483 RD----RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538

Query: 968  ASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPR 1007
              R    +QE         +   +EE + + E++   L R
Sbjct: 1539 QLR----RQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 74/322 (22%), Positives = 143/322 (44%), Gaps = 56/322 (17%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            QE E++  +E +  R RQ  E    K D+ + E+E   +++   R+ +E  RE   +EEE
Sbjct: 998  QEEEQLLREEREK-RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE--RERQYREEE 1054

Query: 750  KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDRE 809
            ++ Q+ ++L   +RE            RRR    +Q ++E EL++ ++++ R+       
Sbjct: 1055 ELQQEEEQLLGEERE-----------TRRRQELERQYRKEEELQQEEEQLLRE------- 1096

Query: 810  IAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIE 869
                  + E R+ +   ++   E+ L + +E L +E R      RR+ +LE     +   
Sbjct: 1097 ------EPEKRRRQERERQCREEEELQQEEEQLLREEREK----RRRQELERQYREE--- 1143

Query: 870  AGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRR 929
              E   Q+ +++++E   K  +         Q L +Q  ++    +  QE  +LLRE + 
Sbjct: 1144 --EEVQQEEEQLLREEPEKRRR---------QELERQYREE---EELQQEEEQLLREEQE 1189

Query: 930  KEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPC 989
            K         +E  ++++E E  + + R  +       +  KW  + E   AV   +  C
Sbjct: 1190 KR-------RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242

Query: 990  H-KEEPRFQNEQDSSCLPRTSQ 1010
              +E  +F+  +DS    R SQ
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQ 1264



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 84/392 (21%), Positives = 171/392 (43%), Gaps = 40/392 (10%)

Query: 685  VDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
            ++ Q ++ E ++ +E   LRE       Q +  Q R E+E   ++++LLR+  E RR   
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135

Query: 745  LQ----EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
            L+    EEE++ Q+ ++L   + E            RRR    +Q ++E EL++ ++++ 
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPE-----------KRRRQELERQYREEEELQQEEEQLL 1184

Query: 801  RKVYMRDREIAATARDLEMR-QLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDL 859
            R+    ++E     R+ + R + EL+ QKR       + +  L  +   + +   R   +
Sbjct: 1185 RE----EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240

Query: 860  -----EEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTD---WQIQSLHKQKCDDL 911
                 E   F +L E  + + +++Q+ ++  L + ++     +   WQ +  H  + + L
Sbjct: 1241 YCKGRENEQFRQL-EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL 1299

Query: 912  QRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFR----LRSAKKASALSD 967
            +R +  Q+ AK  R +R+ + E      E E K+ ++   ++FR    L   ++   L  
Sbjct: 1300 EREE--QKEAK--RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355

Query: 968  ASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNR 1027
              R    ++E     E       +E+   + E++   L    QL    E +   +   +R
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR-CQEREQQLRQDRDR 1414

Query: 1028 --RAVEWDTTGQNLIKKVRNLRQRLTARARHR 1057
              R  E   + Q   +K R   Q++  + R R
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERER 1446



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 70/335 (20%), Positives = 152/335 (45%), Gaps = 36/335 (10%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA-----WYQKQELLRKAEETRREML 744
            ++RER    E    RE++ + + + K  ++R   E      + +++E L++ E   R   
Sbjct: 792  EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE---RAQQ 848

Query: 745  LQEEEKMI---QQRQRLAAVKRELKVKEMHLQDAARRRF-------LKLQQDQQEMELRR 794
            LQEEE  +   Q+R+R    +R+ K +    ++  RRR        L+ Q  +++  L+ 
Sbjct: 849  LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908

Query: 795  LDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYR 854
             ++E+ R+   + R      +  E  QL+ E ++ L E+     ++   ++ R D    +
Sbjct: 909  EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968

Query: 855  RKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRN 914
            +    EE +  +  E    Q ++ +   +E L + E+  L  + + +   + +    +++
Sbjct: 969  K----EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024

Query: 915  KCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE---GKEFRLRSAKKASALSDASRK 971
            +  QE  +LLRE R K        ++E  ++++E E    +E +L   ++ +       +
Sbjct: 1025 ELQQEEEQLLREEREKR------RLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078

Query: 972  WFLKQEINAAVEHAENPCHKEEP--RFQNEQDSSC 1004
             + K+E    ++  E    +EEP  R + E++  C
Sbjct: 1079 QYRKEE---ELQQEEEQLLREEPEKRRRQERERQC 1110



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 70/325 (21%), Positives = 140/325 (43%), Gaps = 21/325 (6%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQ-RVEDEAWYQKQELLRKAEETRREMLLQ 746
            + + ++ ++++E +  R++Q   + Q + +Q+ + E+E    +Q L R+ EE RRE  L 
Sbjct: 627  EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686

Query: 747  EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMR 806
            EEE+  Q R+R   +K  +   +  L+  A  R  K+    ++ E +R   E   K   R
Sbjct: 687  EEEQE-QARER---IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742

Query: 807  DREIAATARDLEMRQLELESQKRLY-------EKNLTENQEALAK-EMRADADAYRRKVD 858
            + E+     +   RQ + E Q+R +       EK+    Q   A+  +R   +   R  +
Sbjct: 743  ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802

Query: 859  LEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNK-CY 917
             ++     L E  E + ++ Q+  +E     E   L  + Q+Q   +++   LQ  +   
Sbjct: 803  RQQREQRFLPEEEEKEQRRRQRREREK----ELQFLEEEEQLQ--RRERAQQLQEEEDGL 856

Query: 918  QEVAKLLRENRRKEIEIINAMVEEEAKKWKEA-EGKEFRLRSAKKASALSDASRKWFLKQ 976
            QE  +  R   ++  +     +EEE K+ +     K       +K   L     +   ++
Sbjct: 857  QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916

Query: 977  EINAAVEHAENPCHKEEPRFQNEQD 1001
            E        +   ++EE + Q E++
Sbjct: 917  EREKRRRQEQERQYREEEQLQQEEE 941



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 80/366 (21%), Positives = 162/366 (44%), Gaps = 50/366 (13%)

Query: 690  QERERIRNDELDYLRE------RQTVEDMQAKVDQQ---RVEDEAWYQKQELLRKAEETR 740
            QERER   +E   LR+      R+  + +Q + +QQ   +  D  + ++++ LR+ E  R
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501

Query: 741  R----EMLLQE-EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRL 795
            +    E+  QE E K +++ Q+L   +R+ K  +   Q   + R  + +QD+     R+ 
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD----RKF 1557

Query: 796  DDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAK-----EMRADA 850
             +E   +    +++++   RD + R  E + +++  E+   E+++ L +     ++R + 
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617

Query: 851  DAYRRK-----VDLEEHMFHK-------LIEAGETQSQKTQKVIKENLAK--AEQACLNT 896
            D   R+      + EE   H+       L E  + + Q+ ++ ++ +  +   E+  L  
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677

Query: 897  DWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGK---E 953
            + + Q L +Q+ D     K  +E  +L R+ R ++      + EE+  + +E E K   E
Sbjct: 1678 EGEEQQLRRQERD----RKFREEEQQLRRQERERKF-----LQEEQQLRRQELERKFREE 1728

Query: 954  FRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEE-PRFQNEQDSSCLPRTSQLN 1012
             +LR   +   L    R   + +E     E  E    ++E  R   E++     R  Q  
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788

Query: 1013 DSSEMD 1018
             S E D
Sbjct: 1789 RSQESD 1794



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 56/263 (21%), Positives = 121/263 (46%), Gaps = 22/263 (8%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            QER+R   +E   LR ++  + ++   D++  E+E   Q+ E  +   + R     +EE+
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698

Query: 750  KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDRE 809
            ++ +Q +    ++ E +++   L+    R+F + +Q +QE E  +L  +   +  + + +
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELE----RKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754

Query: 810  IAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIE 869
            +     + ++R+ E + + R  E+   E +E   +   +D     RK   EE +      
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD-----RKFREEEQL------ 1803

Query: 870  AGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRR 929
              E + Q+ +   ++   + E+  L  + Q Q L +++     R    +E      ++RR
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER----DRQYRAEEQFATQEKSRR 1859

Query: 930  KEIEIINAMVEEEAKKWKEAEGK 952
            +E E+     EEE K+ +E E K
Sbjct: 1860 EEQEL---WQEEEQKRRQERERK 1879



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 69/337 (20%), Positives = 148/337 (43%), Gaps = 32/337 (9%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML-LQEE 748
            +E ER+  +E    R ++   + + +    + E++   ++Q+L R+ +E R + L  +EE
Sbjct: 605  EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664

Query: 749  EKMIQQR--QRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMR 806
            E+ ++QR  +     +RE ++ E   Q+ AR R +K +  + + +L    D    KVY R
Sbjct: 665  EERLEQRLKREHEEERREQELAEEE-QEQARER-IKSRIPKWQWQLESEADARQSKVYSR 722

Query: 807  DREIAATARDLEMRQLELESQKRLYEKNLTENQEALA------KEMRADADAYRRKVDLE 860
             R+     ++ + R+ E E ++R  E  L   +E  A      +E R D     +  +  
Sbjct: 723  PRK-----QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS 777

Query: 861  EHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEV 920
            E    +L      + Q+ +++  E   + EQ  L  + + +   +Q+ +  +  +  +E 
Sbjct: 778  ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837

Query: 921  AKLLRENRRKEIEIINAMVEEEAK-------------KWKEAEGKEFRLRSAKKASALSD 967
             +L R  R ++++     ++E+ +             +W+  E ++ R  +     AL +
Sbjct: 838  EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897

Query: 968  ASRK---WFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
              RK      ++E     E  E    +E+ R   E++
Sbjct: 898  QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 73/343 (21%), Positives = 146/343 (42%), Gaps = 31/343 (9%)

Query: 690  QERERIRNDELD-YLRERQTVEDMQAKVDQQR--VEDEAWYQKQELLRKAEETRREMLLQ 746
            QE ++ R +  D  L E       Q + +Q+R   E E   +KQE L + +  RR+  L 
Sbjct: 115  QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW 174

Query: 747  EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ-----EMELRRLDDEIGR 801
             + +  Q+R+       E + +E  LQ        +   ++Q      +ELRR   E  +
Sbjct: 175  RQRQEWQERE-------ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE-EK 226

Query: 802  KVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEE 861
            +   R+R+      + E    + E+  R  E+ L E +    +E++ + +   RK++ +E
Sbjct: 227  QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL-RKLERQE 285

Query: 862  HMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVA 921
                 L    + + Q+ Q++ +E   + +Q     + Q +   +Q+  + Q  +  Q++ 
Sbjct: 286  -----LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340

Query: 922  KLLRENRRKEI--EIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEIN 979
            +   E R +++  E      E++ ++ +E E +E +LR  ++        R+  L++E  
Sbjct: 341  REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400

Query: 980  AAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQ 1022
               E       + E + + EQ    L R  QL    E +   Q
Sbjct: 401  LRREQQ----LRREQQLRREQQ---LRREQQLRREQEEERHEQ 436



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 67/364 (18%), Positives = 160/364 (43%), Gaps = 32/364 (8%)

Query: 686  DYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL 745
            + ++QE ER   +E   L  +Q       +  Q R ++    ++Q+  RK  E  +    
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566

Query: 746  QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYM 805
            +EE+++ +Q +      R+ +++E  ++   + R  K  +D+Q++  +    ++ ++   
Sbjct: 1567 REEQQLSRQER-----DRKFRLEEQKVRRQEQER--KFMEDEQQLRRQEGQQQLRQERDR 1619

Query: 806  RDREIAATARDLEMRQLELESQKRLY-EKNLTENQEALAKEMRADADAYRRKVDLEEHMF 864
            + RE     ++ E +QL  + + R + E+     ++   +++R D D   RK   EE   
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD---RKFREEE--- 1673

Query: 865  HKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLL 924
             +L++ GE Q  + Q+  ++   + EQ     + + + L +++   L+R    QE+ +  
Sbjct: 1674 -QLLQEGEEQQLRRQERDRK-FREEEQQLRRQERERKFLQEEQ--QLRR----QELERKF 1725

Query: 925  RENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEH 984
            RE  +   E     +  + +  K  E ++ R    ++     +  RK+  ++++    E 
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785

Query: 985  AENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVR 1044
             +    + + +F+ E+      +  Q  +  ++ P  +    R    W+     L ++ +
Sbjct: 1786 QQLRSQESDRKFREEE------QLRQEREEQQLRPQQRDGKYR----WEEEQLQLEEQEQ 1835

Query: 1045 NLRQ 1048
             LRQ
Sbjct: 1836 RLRQ 1839



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 47/226 (20%), Positives = 105/226 (46%), Gaps = 12/226 (5%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
            Q  E +++R  E D     +  +  + + +++ +++E   ++QEL RK  E   E L QE
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE--EEQLRQE 1734

Query: 748  -EEKMIQQRQRLAAVKRELKVK----EMHLQDAAR-RRFLKLQQDQQEMELRRLDDEIGR 801
             E++ +++++R   +  E +++    E  L+   R R+F + +Q +QE E ++L  +   
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794

Query: 802  KVYMRDREIAATARDLEMRQLELESQKRLYEKNL-TENQEALAKEMRADADAYRRKVDLE 860
            + +  + ++     + ++R  + + + R  E+ L  E QE   + +R + D   R  +  
Sbjct: 1795 RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE---QRLRQERDRQYRAEEQF 1851

Query: 861  EHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQ 906
                    E  E   ++ QK  +E   K  +  +    + +  H+Q
Sbjct: 1852 ATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 46/202 (22%), Positives = 94/202 (46%), Gaps = 21/202 (10%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQK--QELLRKAEETRREMLLQE 747
            QE +++R  EL+  R+ +  E ++ + +Q+++  +  Y+K  +E   + E   +++  QE
Sbjct: 1711 QEEQQLRRQELE--RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768

Query: 748  EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVY--- 804
             ++  ++ ++L   + E +++       + R+F + +Q +QE E ++L  +     Y   
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQE----SDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824

Query: 805  ---MRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEE 861
               ++  E     R    RQ   E Q    EK+  E QE   +E +       RK+  EE
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL-REE 1883

Query: 862  HMFHKLIE------AGETQSQK 877
            H+  +  E       GE +SQ+
Sbjct: 1884 HIRRQQKEEQRHRQVGEIKSQE 1905



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 28/108 (25%), Positives = 58/108 (53%), Gaps = 12/108 (11%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA--WYQKQELLRKAEETRREMLL 745
            Q +E +++R  + D  + R   E +Q +  +QR+  E    Y+ +E     E++RR    
Sbjct: 1805 QEREEQQLRPQQRDG-KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR---- 1859

Query: 746  QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELR 793
             EE+++ Q+ ++    +RE K++E H+    RR+  + Q+ +Q  E++
Sbjct: 1860 -EEQELWQEEEQKRRQERERKLREEHI----RRQQKEEQRHRQVGEIK 1902


>gi|219803769 trichoplein [Homo sapiens]
          Length = 498

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 84/326 (25%), Positives = 152/326 (46%), Gaps = 47/326 (14%)

Query: 690 QERERIRNDELDYLR-ERQTVEDMQAKVDQQRVED----EAWYQKQELLRKAEETRREML 744
           QE +R  N+   Y R  R+ +E M+A+ +++++ED    EA  Q+ E L K +E     L
Sbjct: 182 QENKRYENE---YERARREALERMKAEEERRQLEDKLQAEALLQQMEEL-KLKEVEATKL 237

Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFL----------KLQQDQQEME--- 791
            +E+E +++QR  L  ++ E K  E   Q A   RFL          + QQ Q+E+E   
Sbjct: 238 KKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADR 297

Query: 792 -----LRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---A 843
                L   +DE  R    R  ++ A   D+   +  +E Q +L      E Q  L   A
Sbjct: 298 RILQALLEKEDESQRLHLARREQVMA---DVAWMKQAIEEQLQLERAREAELQMLLREEA 354

Query: 844 KEMRADADA-YRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQS 902
           KEM    +A + R+    + +  +++     + Q+ Q+ I++N    E++  + +  I++
Sbjct: 355 KEMWEKREAEWARERSARDRLMSEVLTG---RQQQIQEKIEQNRRAQEESLKHREQLIRN 411

Query: 903 LHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKA 962
           L + +  +L R +  +E ++ L+  R++E+E    + E   + W+  + +E     A++ 
Sbjct: 412 LEEVR--ELARRE--KEESEKLKSARKQELEA--QVAERRLQAWEADQQEEEEEEEARRV 465

Query: 963 SALSDASRKWFLKQEINAAVEHAENP 988
             LSDA     L+QE     E    P
Sbjct: 466 EQLSDA----LLQQEAETMAEQGYRP 487



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 81/397 (20%), Positives = 168/397 (42%), Gaps = 70/397 (17%)

Query: 702  YLRERQTVEDMQAKVDQQRVEDEAWYQKQELL-RKAEETRREMLLQEEEKMIQQRQRLAA 760
            Y RE+   E  ++   ++    +   ++Q+LL R+ EE R  M LQ E ++ +Q  +L +
Sbjct: 67   YQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQ-ERRIREQHGKLKS 125

Query: 761  VKREL------------------KVKEMHL--------------------QDAA------ 776
             K E                   K++EM L                    Q+A       
Sbjct: 126  AKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENK 185

Query: 777  -------RRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKR 829
                   R R   L++ + E E R+L+D++  +  ++  E      +L+++++E    K+
Sbjct: 186  RYENEYERARREALERMKAEEERRQLEDKLQAEALLQQME------ELKLKEVEATKLKK 239

Query: 830  LYEKNLTENQE-ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAK 888
              E  L +  E    +E R   +A+R+K +L   + H+       ++Q+ Q+ ++ +  +
Sbjct: 240  EQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEAD-RR 298

Query: 889  AEQACLNTDWQIQSLHKQKCDDLQRNKCY--QEVAKLLRENRRKEIEIINAMVEEEAKKW 946
              QA L  + + Q LH  + + +  +  +  Q + + L+  R +E E+   + EE  + W
Sbjct: 299  ILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMW 358

Query: 947  KEAEGKEFRLRSAK-KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCL 1005
            ++ E +  R RSA+ +  +     R+  ++++I       E      E   +N ++   L
Sbjct: 359  EKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVREL 418

Query: 1006 PR-----TSQLNDSSEMDPSTQISLNRRAVEWDTTGQ 1037
             R     + +L  + + +   Q++  RR   W+   Q
Sbjct: 419  ARREKEESEKLKSARKQELEAQVA-ERRLQAWEADQQ 454



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 84/418 (20%), Positives = 175/418 (41%), Gaps = 72/418 (17%)

Query: 711  DMQAKVDQQRVEDEAWYQKQELL--RKAEET-----RREMLLQEEEKMIQQRQRLAAVKR 763
            + +A++ QQ  ++  +++  ++   ++AE +     +R M   + EKM ++++R    +R
Sbjct: 25   EQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARR 84

Query: 764  E-LKVKEMHLQDAARRRF--LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDL--- 817
            E L+      QD   R    L+L  + QE   RR+ ++ G+    ++ +    A  L   
Sbjct: 85   EKLRQLMQEEQDLLARELEELRLSMNLQE---RRIREQHGKLKSAKEEQRKLIAEQLLYE 141

Query: 818  -------EMRQLELE-SQKRL-----YEKNLTENQEALAKE---------MRADADAYRR 855
                   ++R++EL+  QK +      +K   + QEA A++          RA  +A  R
Sbjct: 142  HWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALER 201

Query: 856  -KVDLEEHMFHKLIEAGETQSQKTQKVIKE----NLAKAEQACLNTDWQIQSLHKQKCDD 910
             K + E       ++A     Q  +  +KE     L K ++  L   W+++ L +++   
Sbjct: 202  MKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEER-KQ 260

Query: 911  LQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWK-------EAEGKEFRLRSAKKAS 963
            ++  +   E+ + LR     ++      ++EE +  +       E E +  RL  A++  
Sbjct: 261  MEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQ 320

Query: 964  ALSDASRKWFLKQEINAAV---------------EHAENPCHKEEPRFQNEQDSSCLPRT 1008
             ++D +   ++KQ I   +               E A+    K E  +  E+ S+     
Sbjct: 321  VMADVA---WMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARER-SARDRLM 376

Query: 1009 SQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066
            S++    +     +I  NRRA E     +  +  +RNL +      R + ++  L +A
Sbjct: 377  SEVLTGRQQQIQEKIEQNRRAQEESLKHREQL--IRNLEEVRELARREKEESEKLKSA 432


>gi|14150056 trichoplein [Homo sapiens]
          Length = 498

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 84/326 (25%), Positives = 152/326 (46%), Gaps = 47/326 (14%)

Query: 690 QERERIRNDELDYLR-ERQTVEDMQAKVDQQRVED----EAWYQKQELLRKAEETRREML 744
           QE +R  N+   Y R  R+ +E M+A+ +++++ED    EA  Q+ E L K +E     L
Sbjct: 182 QENKRYENE---YERARREALERMKAEEERRQLEDKLQAEALLQQMEEL-KLKEVEATKL 237

Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFL----------KLQQDQQEME--- 791
            +E+E +++QR  L  ++ E K  E   Q A   RFL          + QQ Q+E+E   
Sbjct: 238 KKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADR 297

Query: 792 -----LRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---A 843
                L   +DE  R    R  ++ A   D+   +  +E Q +L      E Q  L   A
Sbjct: 298 RILQALLEKEDESQRLHLARREQVMA---DVAWMKQAIEEQLQLERAREAELQMLLREEA 354

Query: 844 KEMRADADA-YRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQS 902
           KEM    +A + R+    + +  +++     + Q+ Q+ I++N    E++  + +  I++
Sbjct: 355 KEMWEKREAEWARERSARDRLMSEVLTG---RQQQIQEKIEQNRRAQEESLKHREQLIRN 411

Query: 903 LHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKA 962
           L + +  +L R +  +E ++ L+  R++E+E    + E   + W+  + +E     A++ 
Sbjct: 412 LEEVR--ELARRE--KEESEKLKSARKQELEA--QVAERRLQAWEADQQEEEEEEEARRV 465

Query: 963 SALSDASRKWFLKQEINAAVEHAENP 988
             LSDA     L+QE     E    P
Sbjct: 466 EQLSDA----LLQQEAETMAEQGYRP 487



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 81/397 (20%), Positives = 168/397 (42%), Gaps = 70/397 (17%)

Query: 702  YLRERQTVEDMQAKVDQQRVEDEAWYQKQELL-RKAEETRREMLLQEEEKMIQQRQRLAA 760
            Y RE+   E  ++   ++    +   ++Q+LL R+ EE R  M LQ E ++ +Q  +L +
Sbjct: 67   YQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQ-ERRIREQHGKLKS 125

Query: 761  VKREL------------------KVKEMHL--------------------QDAA------ 776
             K E                   K++EM L                    Q+A       
Sbjct: 126  AKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENK 185

Query: 777  -------RRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKR 829
                   R R   L++ + E E R+L+D++  +  ++  E      +L+++++E    K+
Sbjct: 186  RYENEYERARREALERMKAEEERRQLEDKLQAEALLQQME------ELKLKEVEATKLKK 239

Query: 830  LYEKNLTENQE-ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAK 888
              E  L +  E    +E R   +A+R+K +L   + H+       ++Q+ Q+ ++ +  +
Sbjct: 240  EQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEAD-RR 298

Query: 889  AEQACLNTDWQIQSLHKQKCDDLQRNKCY--QEVAKLLRENRRKEIEIINAMVEEEAKKW 946
              QA L  + + Q LH  + + +  +  +  Q + + L+  R +E E+   + EE  + W
Sbjct: 299  ILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMW 358

Query: 947  KEAEGKEFRLRSAK-KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCL 1005
            ++ E +  R RSA+ +  +     R+  ++++I       E      E   +N ++   L
Sbjct: 359  EKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVREL 418

Query: 1006 PR-----TSQLNDSSEMDPSTQISLNRRAVEWDTTGQ 1037
             R     + +L  + + +   Q++  RR   W+   Q
Sbjct: 419  ARREKEESEKLKSARKQELEAQVA-ERRLQAWEADQQ 454



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 84/418 (20%), Positives = 175/418 (41%), Gaps = 72/418 (17%)

Query: 711  DMQAKVDQQRVEDEAWYQKQELL--RKAEET-----RREMLLQEEEKMIQQRQRLAAVKR 763
            + +A++ QQ  ++  +++  ++   ++AE +     +R M   + EKM ++++R    +R
Sbjct: 25   EQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARR 84

Query: 764  E-LKVKEMHLQDAARRRF--LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDL--- 817
            E L+      QD   R    L+L  + QE   RR+ ++ G+    ++ +    A  L   
Sbjct: 85   EKLRQLMQEEQDLLARELEELRLSMNLQE---RRIREQHGKLKSAKEEQRKLIAEQLLYE 141

Query: 818  -------EMRQLELE-SQKRL-----YEKNLTENQEALAKE---------MRADADAYRR 855
                   ++R++EL+  QK +      +K   + QEA A++          RA  +A  R
Sbjct: 142  HWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALER 201

Query: 856  -KVDLEEHMFHKLIEAGETQSQKTQKVIKE----NLAKAEQACLNTDWQIQSLHKQKCDD 910
             K + E       ++A     Q  +  +KE     L K ++  L   W+++ L +++   
Sbjct: 202  MKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEER-KQ 260

Query: 911  LQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWK-------EAEGKEFRLRSAKKAS 963
            ++  +   E+ + LR     ++      ++EE +  +       E E +  RL  A++  
Sbjct: 261  MEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQ 320

Query: 964  ALSDASRKWFLKQEINAAV---------------EHAENPCHKEEPRFQNEQDSSCLPRT 1008
             ++D +   ++KQ I   +               E A+    K E  +  E+ S+     
Sbjct: 321  VMADVA---WMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARER-SARDRLM 376

Query: 1009 SQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066
            S++    +     +I  NRRA E     +  +  +RNL +      R + ++  L +A
Sbjct: 377  SEVLTGRQQQIQEKIEQNRRAQEESLKHREQL--IRNLEEVRELARREKEESEKLKSA 432


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 899

 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 79/371 (21%), Positives = 164/371 (44%), Gaps = 50/371 (13%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL------LRKAEET--RRE 742
            E+  I+ +  +  R+ +  + +  +V    +++E W Q++EL      +RK EE   R+E
Sbjct: 240  EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299

Query: 743  MLLQE--------EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD-------Q 787
              L+E        EEKM +Q +RL   ++EL+ +E  L++    R  + Q         +
Sbjct: 300  ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359

Query: 788  QEMELRRLDDEIGR---------------KVYMRDREIAATARDLEMRQLE--LESQKRL 830
            QE ++R  ++++ R               +  MRD+E     +D  +R+ E  +  Q+++
Sbjct: 360  QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419

Query: 831  YEKNLTENQEALAKEMRADADAYRRKVDLEEHMFH---KLIEAGETQSQKTQKVIKENLA 887
            +E+     +E   +E          K+  EE +     K+ E  ET  ++ +K+ K+   
Sbjct: 420  WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479

Query: 888  KAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWK 947
              EQ     +WQ Q L +QK    ++ K  ++  K+  +   ++I     M  +E K W+
Sbjct: 480  MWEQE--EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ--EEKIRDQEEMWGQEKKMWR 535

Query: 948  EAEGKEFRLRSAKKASALSDASRK-WFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLP 1006
            + + +E   +  ++   + D  +K W  ++ +    +  E     +E + + E+      
Sbjct: 536  QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE--RMRE 593

Query: 1007 RTSQLNDSSEM 1017
            R  ++ +  EM
Sbjct: 594  REKKMREEEEM 604



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 69/319 (21%), Positives = 154/319 (48%), Gaps = 24/319 (7%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            QE ERIR  E     E +T+ + + K+ +Q  E+  W Q+++  ++     ++  L E+E
Sbjct: 447  QEEERIREREKKMREEEETMREQEEKMQKQ--EENMWEQEEKEWQQQRLPEQKEKLWEQE 504

Query: 750  KMIQQRQRLAAVKRELK-VKEMHLQDAA--RRRFLKLQQDQQ-EMELRRLDDEIGRKVYM 805
            KM +Q +++   + +++  +EM  Q+    R+  ++ Q+DQ  E E +  D E  +K++ 
Sbjct: 505  KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE--QKMWD 562

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKE---MRADADAYRRKVDLEEH 862
            ++  +    ++ E +  + E + R  E+ + E ++ + +E   MR   +  + + +  + 
Sbjct: 563  QEERMEKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621

Query: 863  MFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAK 922
               K+ E  E   ++ +K+ ++     EQ      W+ Q L +QK + L  ++  QE  K
Sbjct: 622  QEEKMWEQEEKMQEQEEKMWEQEEKMWEQE--EKMWEQQRLPEQK-EKLWEHEKMQEQEK 678

Query: 923  LLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAV 982
             ++E   K  E      E+  KK +E E K +     ++  ++ +  +K   ++E+   +
Sbjct: 679  -MQEQEEKIWE-----QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM---M 729

Query: 983  EHAENPCHKEEPRFQNEQD 1001
               E    ++E + Q +++
Sbjct: 730  REQEEKMQEQEEKMQEQEE 748



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 52/262 (19%), Positives = 129/262 (49%), Gaps = 10/262 (3%)

Query: 698 DELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQKQELLRKAEETRRE-MLLQEEEKMI 752
           ++ + L E++ +++ + K+ +Q    R ++E W Q++++ R+ +   +E  + ++EEKM 
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554

Query: 753 QQRQRL--AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELR-RLDDEIGRKVYMRDRE 809
            Q Q++     + E K +E   +   +   ++ ++  +E E + R ++E+ R+   + +E
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614

Query: 810 IAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIE 869
                ++ E +  E E + +  E+ + E +E + ++     +  R     E+   H+ ++
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 674

Query: 870 AGETQSQKTQKV-IKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENR 928
             E   ++ +K+  +E + K  Q      W  + + +++    +R K  +E  +++RE  
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE-SMREREKKMREEEEMMREQE 733

Query: 929 RKEIEIINAMVEEEAKKWKEAE 950
            K  E    M E+E + W++ E
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEE 755



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 75/402 (18%), Positives = 174/402 (43%), Gaps = 59/402 (14%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETR--REMLL 745
            + +E++ +R  E     + + + + + K+ +Q  E++ W Q++ L  + ++ R   + + 
Sbjct: 336  ELREQKELREQEEQMQEQEEKMWEQEEKMREQ--EEKMWRQEERLWEQEKQMREQEQKMR 393

Query: 746  QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYM 805
             +EE+M +Q +RL   +  ++ +E   +   + R  K  Q +QE + R  ++++  +  +
Sbjct: 394  DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ-EQEKKTRDQEEKMQEEERI 452

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYR----------- 854
            R+RE      +  MR+ E + QK+  E+N+ E +E   ++ R      +           
Sbjct: 453  REREKKMREEEETMREQEEKMQKQ--EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 510

Query: 855  -------RKVDLEEHMF----------------HKLIEAGETQSQKTQKV--IKENLAKA 889
                    K+  +E M+                 ++ E  E    + QK+   +E + K 
Sbjct: 511  EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570

Query: 890  EQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEA 949
             Q      W  +   +++    +R K  +E  +++RE   K  E    M E+E K W++ 
Sbjct: 571  TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630

Query: 950  EG-KEFRLRSAKKASALSDASRKWFLKQEINAAVEHA-ENPCHKEEPRFQNEQDSSCLPR 1007
            E  +E   +  ++   + +   K + +Q +    E   E+   +E+ + Q +++      
Sbjct: 631  EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE------ 684

Query: 1008 TSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQR 1049
              ++ +  +M+  TQ    +    WD   Q  +++  ++R+R
Sbjct: 685  --KIWEQEKMEKKTQ---EQEKKTWD---QEKMREEESMRER 718



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 56/328 (17%), Positives = 151/328 (46%), Gaps = 30/328 (9%)

Query: 685  VDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREM- 743
            ++ +TQE+E+   D+ + +RE + + + + K+   R E+E   +++E +++ EE  +E  
Sbjct: 567  MEKKTQEQEKKTWDQEEKMREEERMREREKKM---REEEEMMREQEEKMQEQEEKMQEQE 623

Query: 744  --LLQEEEKMIQQRQRL-----AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLD 796
              + ++EEKM +Q +++        ++E K+ E       + +  + ++ Q++ +++  +
Sbjct: 624  EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683

Query: 797  DEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK 856
            ++I  +  M  +      +  +  ++  E   R  EK + E +E + ++     +   + 
Sbjct: 684  EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKM 743

Query: 857  VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKC 916
             + EE M+    E  E   ++ +K+ ++     ++  L   W+ + + +Q+    Q  K 
Sbjct: 744  QEQEEEMW----EQEEKMWEQEEKMWEQQRLPEQKEKL---WEHEKMQEQEKIWEQEEKM 796

Query: 917  YQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE---GKEFRLRSAKKASALSDASRKWF 973
              +  K +R    K       M  +E K W + E   G+E ++   ++        + W 
Sbjct: 797  RDQEEK-MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE--------KMWG 847

Query: 974  LKQEINAAVEHAENPCHKEEPRFQNEQD 1001
             ++++   ++  E    ++E + + +++
Sbjct: 848  QEEKMEEKMQGQEEKMREQEEKMRGQEE 875



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 58/337 (17%), Positives = 145/337 (43%), Gaps = 31/337 (9%)

Query: 692  RERIRNDELDYLRERQTVEDMQAKV--DQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            +E++R  E     + + + D + K+   ++R+E +   Q+++   + E+ R E  ++E E
Sbjct: 536  QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595

Query: 750  KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDRE 809
            K +++ + +   + E   ++         +  + ++  QE E +  + E   K++ ++ +
Sbjct: 596  KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE--EKMWEQEEK 653

Query: 810  IAATARDLEMRQLELESQKRLYEKNLTENQEAL-------------------AKEMRADA 850
            +    R  E ++   E +K   ++ + E +E +                    ++MR + 
Sbjct: 654  MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713

Query: 851  DAYRR--KVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTD--WQIQSLHKQ 906
                R  K+  EE M  +  E  + Q +K Q+  +E   + E+     +  W+ Q L +Q
Sbjct: 714  SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773

Query: 907  KCDDLQRNKCYQEVAKL--LRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASA 964
            K + L  ++  QE  K+    E  R + E +    E+   + ++  G+E ++   ++   
Sbjct: 774  K-EKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM-WGQEEKM 831

Query: 965  LSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
                 + W  ++++    E  E     +E + + +++
Sbjct: 832  WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 71/316 (22%), Positives = 147/316 (46%), Gaps = 39/316 (12%)

Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL------LRKAEET--RRE 742
           E+  I+ +  +  R+ +  + +  +V    +++E W Q++EL      +RK EE   R+E
Sbjct: 202 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 261

Query: 743 MLLQE--------EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRR 794
             L+E        EEKM +Q +RL   ++EL+ +E  L++  + R  + Q  +QE ++  
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321

Query: 795 LDD---EIGRKVYMRD----------REIAATARDLEMRQLELESQKRLYEKNLTENQEA 841
            ++   E   K++ ++          RE     RD E R  E + + R  E+ + E ++ 
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381

Query: 842 LAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQ 901
             +E +   +   R+ +       K+ E  ET  ++ +K+ K+     EQ     +WQ Q
Sbjct: 382 WEQEEKMQEEERIRERE------KKMREEEETMREQEEKMQKQEENMWEQE--EKEWQQQ 433

Query: 902 SLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKK 961
            L +QK    ++ K  ++  K+  +   ++I     M  +E K W++ + +E   +  ++
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEKIWEQ--EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491

Query: 962 ASALSDASRKWFLKQE 977
              + D  +K + ++E
Sbjct: 492 EEKMRDQEQKMWDQEE 507



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 69/331 (20%), Positives = 152/331 (45%), Gaps = 33/331 (9%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            QE +  R +E  + +E+Q  E  Q   DQ   E+  W Q + L  K E  R +  + E+E
Sbjct: 329  QEEKMWRQEERLWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQE 385

Query: 750  KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQ--------QDQQEMELRRLDDE--- 798
            + +Q+ +R+   +RE K++E   ++  R +  K+Q        Q+++E + +RL ++   
Sbjct: 386  EKMQEEERIR--EREKKMREE--EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441

Query: 799  IGRKVYMRDREIAATARDLEMRQLEL---ESQKRLYEKNLTENQEALAKEMRADADAYRR 855
            +  +  M+++E     ++ ++R  E    + +K   ++ + E ++ + ++     D  ++
Sbjct: 442  LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501

Query: 856  KVDLEEHMFH---KLIEAGETQSQKTQKVIKENLAKAEQACLNTD---WQIQSLHKQKCD 909
              D EE M+    +L E  E   ++ +   +E   + E+     +   W  +   +++  
Sbjct: 502  MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561

Query: 910  DLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDAS 969
              +R K  +E  +++RE   K  E    M E+E K W++ E      +  ++   + +  
Sbjct: 562  MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE------KMQEQEEKMWEQE 615

Query: 970  RKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 1000
             K + ++E +   E  E    +EE   + E+
Sbjct: 616  EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 59/284 (20%), Positives = 132/284 (46%), Gaps = 14/284 (4%)

Query: 673 QYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL 732
           Q  ++ Q  K   + + +ERE+   +E + +RE++  E MQ + +    ++E  +Q+Q L
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQE--EKMQKQEENMWEQEEKEWQQQRL 435

Query: 733 LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ-EME 791
             + E+   +  +QE+E+ I +++     + E+  +E  +    R+  ++ Q+DQ  E E
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW---RQEKMREQEDQMWEQE 492

Query: 792 LRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADAD 851
            +  D E  +K++ ++  +      L  ++  +  QK+++++     +E   +E      
Sbjct: 493 EKMRDQE--QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550

Query: 852 AYRRKVDLEEHMFH---KLIEAGETQSQKTQKV--IKENLAKAEQACLNTDWQIQSLHKQ 906
               K+  EE M     K+ E  E   ++ +K+   +E + + E+     + ++Q   ++
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE-QEE 609

Query: 907 KCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
           K  + +     QE    ++E      E    M E+E K W++ E
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 64/344 (18%), Positives = 154/344 (44%), Gaps = 38/344 (11%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQ---RVEDEAWYQKQELLRKAEETRREMLLQ 746
            ++ E++R  E     + + + + + ++ +Q   R ++E   +++E + + EE  RE    
Sbjct: 273  EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE---- 328

Query: 747  EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFL---KLQQDQQEM----ELRRLDDEI 799
            +EEKM +Q +RL   +++++ +E  ++D   R +    +L++ ++ M    ++   ++++
Sbjct: 329  QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388

Query: 800  GRKVYMRDREIAATARDLEMRQLELESQKR---LYEKNLTENQEALAKEMRADADAYRRK 856
              +  +R+RE      +  MR+ E + QK+   ++E+   E Q+    E +       + 
Sbjct: 389  QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448

Query: 857  VDLEEHMF---HKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQR 913
             + EE ++    K+ +  E   Q+ +   +E + + E       W+     ++K  D ++
Sbjct: 449  QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM----WE----QEEKMRDQEQ 500

Query: 914  NKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWF 973
                QE     ++ R +E E     + E+ K W++ E    ++R  KK        + W 
Sbjct: 501  KMWDQEERMWEQDERLREKE---ERMREQKKMWQQEE----KMREEKKTQ--EQEKKTWD 551

Query: 974  LKQEINAAVEHAENPCH-KEEPRFQNEQDSSCLPRTSQLNDSSE 1016
             ++++       E     +EE     EQ+     +  ++ +  E
Sbjct: 552  QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 57/335 (17%), Positives = 151/335 (45%), Gaps = 24/335 (7%)

Query: 698  DELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQ-----KQELLRKAEE---TRREMLL 745
            ++ + L E++ +++ + K+ +Q    R ++E W Q     +QE +R+ E+    + E + 
Sbjct: 437  EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496

Query: 746  QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYM 805
             +E+KM  Q +R+      L+ KE  +++       K+ Q +++M   +   E  +K + 
Sbjct: 497  DQEQKMWDQEERMWEQDERLREKEERMREQK-----KMWQQEEKMREEKKTQEQEKKTWD 551

Query: 806  RDREI--AATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHM 863
            ++ ++      R+ E +  E E   R  E+ + E +E + ++     +   +  + EE M
Sbjct: 552  QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611

Query: 864  FHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKL 923
            + +  +  E + +   +  +E + + E+     + ++    ++  +  ++ +  +E  + 
Sbjct: 612  WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 671

Query: 924  LRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVE 983
              E  R++ E +    E+  ++ ++  G+E ++   ++   +     K + ++E+    E
Sbjct: 672  QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE--KMWGQEEKMWGQEEMREKEE 729

Query: 984  HAENPCHKEEPRFQNEQD---SSCLPRTSQLNDSS 1015
               +   K + R    ++     CLP +  L + S
Sbjct: 730  RIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMS 764



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 50/234 (21%), Positives = 112/234 (47%), Gaps = 17/234 (7%)

Query: 673 QYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL 732
           Q  ++ Q  K   + +TQE+E+   D+ + +RE + + + + K+   R E+E   +++E 
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM---REEEEMMREQEEK 582

Query: 733 LRKAEETRREM---LLQEEEKMIQQRQRLAAVKRELKVKE----MHLQDAARRRFLKLQQ 785
           +++ EE  RE    + ++EEKM +Q +++   + ++  +E    M  Q+       +  Q
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642

Query: 786 DQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKE 845
           +Q+E    + +    ++  MR++E     ++ +MR+ E + Q +  E+ + E +E +  +
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ--EEKMREQEEKMRGQ 700

Query: 846 MRADADAYRRKVDLEEHMF-----HKLIEAGETQSQKTQKVIKENLAKAEQACL 894
                    +    EE M+      +  E    Q +K Q+ + E+  +  + CL
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCL 754



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 52/308 (16%), Positives = 133/308 (43%), Gaps = 44/308 (14%)

Query: 686 DYQTQERERIRNDELDYLRERQTV----EDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
           D   ++ E++R+ E     + + +    E ++ K ++ R + + W Q++++  + +   +
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545

Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
           E    ++E+ +++ +R+   +RE K++E   ++  R +  K+Q+ +++M           
Sbjct: 546 EKKTWDQEEKMREEERMR--EREKKMREE--EEMMREQEEKMQEQEEKM----------- 590

Query: 802 KVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEE 861
                        R+ E +  E E + +  E+ + E +E + ++   D      K+  +E
Sbjct: 591 -------------REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED------KMQEQE 631

Query: 862 HMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVA 921
            M  +  E  + Q +K  +  +E + + E+     + ++Q   ++  +  ++ +  +E  
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQ-EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690

Query: 922 KLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAA 981
           +   E  R + E    M  +E K W + E    +    +K   + D   K  +++ +   
Sbjct: 691 REQEEKMRGQEE---KMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK--MQERLPEH 745

Query: 982 VEHAENPC 989
            E    PC
Sbjct: 746 EERCSEPC 753



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 64/302 (21%), Positives = 118/302 (39%), Gaps = 34/302 (11%)

Query: 734  RKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELR 793
            +KA    +E L +E E      + L   K EL+    + QDAAR+         ++  L 
Sbjct: 73   KKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARK--------FEDGNLG 124

Query: 794  RLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMR----AD 849
               D  GR         A   +           +   Y + LT+ ++AL+ E+      +
Sbjct: 125  ESKDLAGR--LHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITN 182

Query: 850  ADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE----QACLNTDWQIQSLHK 905
             +  ++  +L+E +  +L E+ +++ Q   K +K  L +A+    Q   NT  +     +
Sbjct: 183  EELKKKNAELQEKL--RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240

Query: 906  QKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAK----------KWKEAEGKEFR 955
            ++  + ++    QE     +E R +E E    M E+E K          + KE   +E  
Sbjct: 241  EELREQEKKIRKQEEKMWRQEERLREQE--GKMREQEEKMRRQEKRLREQEKELREQEKE 298

Query: 956  LRSAKKASALSDASRKWFLKQ-EINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDS 1014
            LR  KK     +  ++   K  E    +   E    ++E R   EQ+     +  ++ D 
Sbjct: 299  LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW-EQEKQMREQEQKMRDQ 357

Query: 1015 SE 1016
             E
Sbjct: 358  EE 359


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 73/283 (25%), Positives = 148/283 (52%), Gaps = 38/283 (13%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQ--RVEDEAWYQKQELLRKAEETRREMLL 745
           Q Q+ E+ +  +L+  +ER+  E M+AK +++  + ++E   Q++E+LR+ +E  R+   
Sbjct: 719 QLQQLEKAKAAKLE--QERREAE-MRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775

Query: 746 QEE-------EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
           +EE       E + +QR++  A++R+ + +E   Q+ A RR   L++ ++E E RR  +E
Sbjct: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR---LEERRREEEERRKQEE 832

Query: 799 IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK-- 856
           + RK   ++ E A  AR+      E E+Q+RL E  L   +E  A  +R + +  +RK  
Sbjct: 833 LLRK---QEEEAAKWARE------EEEAQRRLEENRLRMEEE--AARLRHEEEERKRKEL 881

Query: 857 -VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDD----- 910
            V  ++ +  +  +  E   +  Q+  ++ LA+ +    +T W  QS +   C       
Sbjct: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQS-NTTACQSQATLS 939

Query: 911 -LQRNKCYQEVAKLLR-ENRRKEIEIINAMVEEEAKKWKEAEG 951
             +  K  +E  + LR E RR++ E++ A+ +++ ++ ++  G
Sbjct: 940 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 982



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 68/279 (24%), Positives = 121/279 (43%), Gaps = 58/279 (20%)

Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
           LQ+ EK     ++Q +R A ++ + + +E   Q+  RR+  ++ + QQE E  RR ++E+
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779

Query: 800 GRKVY------MRDREIA-ATARDLEMRQLELESQKRLYEKN------------LTENQE 840
            R+         R++EIA    R+ E RQ + E+ +RL E+             L + +E
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839

Query: 841 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
             AK  R + +A RR   LEE+      EA   + ++ ++  KE                
Sbjct: 840 EAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKE---------------- 880

Query: 901 QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960
             L  Q+  +L R +  Q+ A L R  ++++ + +  M    +  W    G++    + +
Sbjct: 881 --LEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQMKLPSSSTW----GQQSNTTACQ 933

Query: 961 KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 999
             + LS A        EI    E  E    +E+ R Q E
Sbjct: 934 SQATLSLA--------EIQKLEEERERQLREEQRRQQRE 964



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 73/367 (19%), Positives = 131/367 (35%), Gaps = 94/367 (25%)

Query: 691  ERERI-RNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            ++ER+ R  EL  L + Q ++  Q  + QQ  +  A  QK  L  + ++ +  +LLQ+ +
Sbjct: 600  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQ-QLALLLQQFQ 658

Query: 750  KM---IQQRQRLAAVKRELKVKEM------------------------------------ 770
             +   I  +  + +V R + V +                                     
Sbjct: 659  TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 718

Query: 771  HLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRL 830
             LQ   + +  KL+Q+++E E+R   +E  RK   R  E+     ++  RQ E E ++R 
Sbjct: 719  QLQQLEKAKAAKLEQERREAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRRE 775

Query: 831  YEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
             E+     QE   +  R    A RR+ + EE            Q ++  + ++E   + E
Sbjct: 776  EEELARRKQEEALRRQREQEIALRRQREEEERQ----------QQEEALRRLEERRREEE 825

Query: 891  QACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
            +                                    RRK+ E++    EEEA KW   E
Sbjct: 826  E------------------------------------RRKQEELLRKQ-EEEAAKWAREE 848

Query: 951  GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 1010
             +  R     +     +A+R   L+ E             ++E   Q +Q    L R  Q
Sbjct: 849  EEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 905

Query: 1011 LNDSSEM 1017
                 ++
Sbjct: 906  QQQQQQL 912


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
          Length = 1320

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 73/283 (25%), Positives = 148/283 (52%), Gaps = 38/283 (13%)

Query: 688  QTQERERIRNDELDYLRERQTVEDMQAKVDQQ--RVEDEAWYQKQELLRKAEETRREMLL 745
            Q Q+ E+ +  +L+  +ER+  E M+AK +++  + ++E   Q++E+LR+ +E  R+   
Sbjct: 746  QLQQLEKAKAAKLE--QERREAE-MRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802

Query: 746  QEE-------EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
            +EE       E + +QR++  A++R+ + +E   Q+ A RR   L++ ++E E RR  +E
Sbjct: 803  EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR---LEERRREEEERRKQEE 859

Query: 799  IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK-- 856
            + RK   ++ E A  AR+      E E+Q+RL E  L   +E  A  +R + +  +RK  
Sbjct: 860  LLRK---QEEEAAKWARE------EEEAQRRLEENRLRMEEE--AARLRHEEEERKRKEL 908

Query: 857  -VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDD----- 910
             V  ++ +  +  +  E   +  Q+  ++ LA+ +    +T W  QS +   C       
Sbjct: 909  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQS-NTTACQSQATLS 966

Query: 911  -LQRNKCYQEVAKLLR-ENRRKEIEIINAMVEEEAKKWKEAEG 951
              +  K  +E  + LR E RR++ E++ A+ +++ ++ ++  G
Sbjct: 967  LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 1009



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 68/279 (24%), Positives = 121/279 (43%), Gaps = 58/279 (20%)

Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
           LQ+ EK     ++Q +R A ++ + + +E   Q+  RR+  ++ + QQE E  RR ++E+
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806

Query: 800 GRKVY------MRDREIA-ATARDLEMRQLELESQKRLYEKN------------LTENQE 840
            R+         R++EIA    R+ E RQ + E+ +RL E+             L + +E
Sbjct: 807 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 866

Query: 841 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
             AK  R + +A RR   LEE+      EA   + ++ ++  KE                
Sbjct: 867 EAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKE---------------- 907

Query: 901 QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960
             L  Q+  +L R +  Q+ A L R  ++++ + +  M    +  W    G++    + +
Sbjct: 908 --LEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQMKLPSSSTW----GQQSNTTACQ 960

Query: 961 KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 999
             + LS A        EI    E  E    +E+ R Q E
Sbjct: 961 SQATLSLA--------EIQKLEEERERQLREEQRRQQRE 991



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 73/367 (19%), Positives = 131/367 (35%), Gaps = 94/367 (25%)

Query: 691  ERERI-RNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            ++ER+ R  EL  L + Q ++  Q  + QQ  +  A  QK  L  + ++ +  +LLQ+ +
Sbjct: 627  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQ-QLALLLQQFQ 685

Query: 750  KM---IQQRQRLAAVKRELKVKEM------------------------------------ 770
             +   I  +  + +V R + V +                                     
Sbjct: 686  TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 745

Query: 771  HLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRL 830
             LQ   + +  KL+Q+++E E+R   +E  RK   R  E+     ++  RQ E E ++R 
Sbjct: 746  QLQQLEKAKAAKLEQERREAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRRE 802

Query: 831  YEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
             E+     QE   +  R    A RR+ + EE            Q ++  + ++E   + E
Sbjct: 803  EEELARRKQEEALRRQREQEIALRRQREEEERQ----------QQEEALRRLEERRREEE 852

Query: 891  QACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
            +                                    RRK+ E++    EEEA KW   E
Sbjct: 853  E------------------------------------RRKQEELLRKQ-EEEAAKWAREE 875

Query: 951  GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 1010
             +  R     +     +A+R   L+ E             ++E   Q +Q    L R  Q
Sbjct: 876  EEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 932

Query: 1011 LNDSSEM 1017
                 ++
Sbjct: 933  QQQQQQL 939


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 73/283 (25%), Positives = 148/283 (52%), Gaps = 38/283 (13%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQ--RVEDEAWYQKQELLRKAEETRREMLL 745
           Q Q+ E+ +  +L+  +ER+  E M+AK +++  + ++E   Q++E+LR+ +E  R+   
Sbjct: 725 QLQQLEKAKAAKLE--QERREAE-MRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781

Query: 746 QEE-------EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
           +EE       E + +QR++  A++R+ + +E   Q+ A RR   L++ ++E E RR  +E
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR---LEERRREEEERRKQEE 838

Query: 799 IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK-- 856
           + RK   ++ E A  AR+      E E+Q+RL E  L   +E  A  +R + +  +RK  
Sbjct: 839 LLRK---QEEEAAKWARE------EEEAQRRLEENRLRMEEE--AARLRHEEEERKRKEL 887

Query: 857 -VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDD----- 910
            V  ++ +  +  +  E   +  Q+  ++ LA+ +    +T W  QS +   C       
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQS-NTTACQSQATLS 945

Query: 911 -LQRNKCYQEVAKLLR-ENRRKEIEIINAMVEEEAKKWKEAEG 951
             +  K  +E  + LR E RR++ E++ A+ +++ ++ ++  G
Sbjct: 946 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 988



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 68/279 (24%), Positives = 121/279 (43%), Gaps = 58/279 (20%)

Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
           LQ+ EK     ++Q +R A ++ + + +E   Q+  RR+  ++ + QQE E  RR ++E+
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785

Query: 800 GRKVY------MRDREIA-ATARDLEMRQLELESQKRLYEKN------------LTENQE 840
            R+         R++EIA    R+ E RQ + E+ +RL E+             L + +E
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845

Query: 841 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
             AK  R + +A RR   LEE+      EA   + ++ ++  KE                
Sbjct: 846 EAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKE---------------- 886

Query: 901 QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960
             L  Q+  +L R +  Q+ A L R  ++++ + +  M    +  W    G++    + +
Sbjct: 887 --LEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQMKLPSSSTW----GQQSNTTACQ 939

Query: 961 KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 999
             + LS A        EI    E  E    +E+ R Q E
Sbjct: 940 SQATLSLA--------EIQKLEEERERQLREEQRRQQRE 970



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 73/367 (19%), Positives = 131/367 (35%), Gaps = 94/367 (25%)

Query: 691  ERERI-RNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            ++ER+ R  EL  L + Q ++  Q  + QQ  +  A  QK  L  + ++ +  +LLQ+ +
Sbjct: 606  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQ-QLALLLQQFQ 664

Query: 750  KM---IQQRQRLAAVKRELKVKEM------------------------------------ 770
             +   I  +  + +V R + V +                                     
Sbjct: 665  TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 724

Query: 771  HLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRL 830
             LQ   + +  KL+Q+++E E+R   +E  RK   R  E+     ++  RQ E E ++R 
Sbjct: 725  QLQQLEKAKAAKLEQERREAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRRE 781

Query: 831  YEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
             E+     QE   +  R    A RR+ + EE            Q ++  + ++E   + E
Sbjct: 782  EEELARRKQEEALRRQREQEIALRRQREEEERQ----------QQEEALRRLEERRREEE 831

Query: 891  QACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
            +                                    RRK+ E++    EEEA KW   E
Sbjct: 832  E------------------------------------RRKQEELLRKQ-EEEAAKWAREE 854

Query: 951  GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 1010
             +  R     +     +A+R   L+ E             ++E   Q +Q    L R  Q
Sbjct: 855  EEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911

Query: 1011 LNDSSEM 1017
                 ++
Sbjct: 912  QQQQQQL 918


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 73/283 (25%), Positives = 148/283 (52%), Gaps = 38/283 (13%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQ--RVEDEAWYQKQELLRKAEETRREMLL 745
           Q Q+ E+ +  +L+  +ER+  E M+AK +++  + ++E   Q++E+LR+ +E  R+   
Sbjct: 725 QLQQLEKAKAAKLE--QERREAE-MRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781

Query: 746 QEE-------EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
           +EE       E + +QR++  A++R+ + +E   Q+ A RR   L++ ++E E RR  +E
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR---LEERRREEEERRKQEE 838

Query: 799 IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK-- 856
           + RK   ++ E A  AR+      E E+Q+RL E  L   +E  A  +R + +  +RK  
Sbjct: 839 LLRK---QEEEAAKWARE------EEEAQRRLEENRLRMEEE--AARLRHEEEERKRKEL 887

Query: 857 -VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDD----- 910
            V  ++ +  +  +  E   +  Q+  ++ LA+ +    +T W  QS +   C       
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQS-NTTACQSQATLS 945

Query: 911 -LQRNKCYQEVAKLLR-ENRRKEIEIINAMVEEEAKKWKEAEG 951
             +  K  +E  + LR E RR++ E++ A+ +++ ++ ++  G
Sbjct: 946 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG 988



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 68/279 (24%), Positives = 121/279 (43%), Gaps = 58/279 (20%)

Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
           LQ+ EK     ++Q +R A ++ + + +E   Q+  RR+  ++ + QQE E  RR ++E+
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785

Query: 800 GRKVY------MRDREIA-ATARDLEMRQLELESQKRLYEKN------------LTENQE 840
            R+         R++EIA    R+ E RQ + E+ +RL E+             L + +E
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845

Query: 841 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
             AK  R + +A RR   LEE+      EA   + ++ ++  KE                
Sbjct: 846 EAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKE---------------- 886

Query: 901 QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960
             L  Q+  +L R +  Q+ A L R  ++++ + +  M    +  W    G++    + +
Sbjct: 887 --LEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQMKLPSSSTW----GQQSNTTACQ 939

Query: 961 KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 999
             + LS A        EI    E  E    +E+ R Q E
Sbjct: 940 SQATLSLA--------EIQKLEEERERQLREEQRRQQRE 970



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 73/367 (19%), Positives = 131/367 (35%), Gaps = 94/367 (25%)

Query: 691  ERERI-RNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
            ++ER+ R  EL  L + Q ++  Q  + QQ  +  A  QK  L  + ++ +  +LLQ+ +
Sbjct: 606  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQ-QLALLLQQFQ 664

Query: 750  KM---IQQRQRLAAVKRELKVKEM------------------------------------ 770
             +   I  +  + +V R + V +                                     
Sbjct: 665  TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 724

Query: 771  HLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRL 830
             LQ   + +  KL+Q+++E E+R   +E  RK   R  E+     ++  RQ E E ++R 
Sbjct: 725  QLQQLEKAKAAKLEQERREAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRRE 781

Query: 831  YEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
             E+     QE   +  R    A RR+ + EE            Q ++  + ++E   + E
Sbjct: 782  EEELARRKQEEALRRQREQEIALRRQREEEERQ----------QQEEALRRLEERRREEE 831

Query: 891  QACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
            +                                    RRK+ E++    EEEA KW   E
Sbjct: 832  E------------------------------------RRKQEELLRKQ-EEEAAKWAREE 854

Query: 951  GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 1010
             +  R     +     +A+R   L+ E             ++E   Q +Q    L R  Q
Sbjct: 855  EEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911

Query: 1011 LNDSSEM 1017
                 ++
Sbjct: 912  QQQQQQL 918


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 79/306 (25%), Positives = 140/306 (45%), Gaps = 28/306 (9%)

Query: 650 METTPTDIHPDSMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTV 709
           M  TPT   P S++  F+   K   P+        V+ + Q  E +R  E      RQ V
Sbjct: 504 MLMTPTSA-PRSVMKSFI---KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKV 559

Query: 710 EDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAV-KRELKVK 768
           E+     D++R  +E   +++E LRK  + R  +   +EEK  Q  Q+ A + ++  K K
Sbjct: 560 EE-----DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 614

Query: 769 EMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQK 828
           E  L +   ++    ++  +E+E RR  +E  R++    +E      + E R  EL  QK
Sbjct: 615 EERLAEEKAKKKAAAKK-MEEVEARRKQEEEARRLRWLQQE------EEERRHQEL-LQK 666

Query: 829 RLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAK 888
           +  E+     + A AK +    +  RR+ +  E    +  E  E + ++ ++ + E   +
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQE-RREQERREQERREQERQLAEQERR 725

Query: 889 AEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIE---IINAMVEEEAKK 945
            EQ  L  + ++Q   ++K   LQ+ +  +E    L E ++KE +       + EE+ KK
Sbjct: 726 REQERLQAERELQ--EREKALRLQKEQLQRE----LEEKKKKEEQQRLAERQLQEEQEKK 779

Query: 946 WKEAEG 951
            KEA G
Sbjct: 780 AKEAAG 785



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 54/200 (27%), Positives = 99/200 (49%), Gaps = 32/200 (16%)

Query: 685 VDYQTQE--RERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA----WYQKQELLRKAEE 738
           +D +T++   ER+  ++       + +E+++A+  Q   E+EA    W Q++E     EE
Sbjct: 606 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ---EEEARRLRWLQQEE-----EE 657

Query: 739 TRREMLLQEEEKMIQQRQRLAA-VKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
            R + LLQ++++  Q+R R AA  KR  + +E   ++  RR   + +Q+++E E R  + 
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717

Query: 798 EIGRKVYMRDREIAATARDLEMRQLEL-----------------ESQKRLYEKNLTENQE 840
           ++  +   R++E     R+L+ R+  L                 E Q+RL E+ L E QE
Sbjct: 718 QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 777

Query: 841 ALAKEMRADADAYRRKVDLE 860
             AKE    + A    VD++
Sbjct: 778 KKAKEAAGASKALNVTVDVQ 797



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 39/209 (18%), Positives = 89/209 (42%), Gaps = 17/209 (8%)

Query: 857  VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKC 916
            V+ E      L    E +  + QKV ++   + E+  L  + +++ + + +         
Sbjct: 535  VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR--------- 585

Query: 917  YQEVAKLLRENRRKEIEIINAMVEEE---AKKWKEAEGKEFRLRSAKKASALSDASRKWF 973
              E  + ++E ++K+IE   A ++E+   AK+ + AE K  +  +AKK   +    ++  
Sbjct: 586  --ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643

Query: 974  LKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ---LNDSSEMDPSTQISLNRRAV 1030
              + +    +  E   H+E  + + E++   L + ++   L +  E +   Q    +   
Sbjct: 644  EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703

Query: 1031 EWDTTGQNLIKKVRNLRQRLTARARHRCQ 1059
            E +   Q   ++ R L ++   R + R Q
Sbjct: 704  EQERREQERREQERQLAEQERRREQERLQ 732


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 67/266 (25%), Positives = 127/266 (47%), Gaps = 19/266 (7%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
           +E+ER R + L    E + +   + + D++R  +E   +++E LRK  + R  +   +EE
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590

Query: 750 KMIQQRQRLAAV-KRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDR 808
           K  Q  Q+ A + ++  K KE  L +   ++    ++  +E+E RR  +E  R++    +
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK-MEEVEARRKQEEEARRLRWLQQ 649

Query: 809 EIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLI 868
           E      + E R  EL  QK+  E+     + A AK +    +  RR+ +  E    +  
Sbjct: 650 E------EEERRHQEL-LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE-RREQ 701

Query: 869 EAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENR 928
           E  E + ++ ++ + E   + EQ  L  + ++Q   ++K   LQ+ +  +E    L E +
Sbjct: 702 ERREQERREQERQLAEQERRREQERLQAERELQ--EREKALRLQKEQLQRE----LEEKK 755

Query: 929 RKEIE---IINAMVEEEAKKWKEAEG 951
           +KE +       + EE+ KK KEA G
Sbjct: 756 KKEEQQRLAERQLQEEQEKKAKEAAG 781



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 54/200 (27%), Positives = 99/200 (49%), Gaps = 32/200 (16%)

Query: 685 VDYQTQE--RERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA----WYQKQELLRKAEE 738
           +D +T++   ER+  ++       + +E+++A+  Q   E+EA    W Q++E     EE
Sbjct: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ---EEEARRLRWLQQEE-----EE 653

Query: 739 TRREMLLQEEEKMIQQRQRLAA-VKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
            R + LLQ++++  Q+R R AA  KR  + +E   ++  RR   + +Q+++E E R  + 
Sbjct: 654 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713

Query: 798 EIGRKVYMRDREIAATARDLEMRQLEL-----------------ESQKRLYEKNLTENQE 840
           ++  +   R++E     R+L+ R+  L                 E Q+RL E+ L E QE
Sbjct: 714 QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773

Query: 841 ALAKEMRADADAYRRKVDLE 860
             AKE    + A    VD++
Sbjct: 774 KKAKEAAGASKALNVTVDVQ 793



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 38/206 (18%), Positives = 87/206 (42%), Gaps = 17/206 (8%)

Query: 860  EEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQE 919
            E      L    E +  + QKV ++   + E+  L  + +++ + + +           E
Sbjct: 534  ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR-----------E 582

Query: 920  VAKLLRENRRKEIEIINAMVEEE---AKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQ 976
              + ++E ++K+IE   A ++E+   AK+ + AE K  +  +AKK   +    ++    +
Sbjct: 583  RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642

Query: 977  EINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ---LNDSSEMDPSTQISLNRRAVEWD 1033
             +    +  E   H+E  + + E++   L + ++   L +  E +   Q    +   E +
Sbjct: 643  RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 702

Query: 1034 TTGQNLIKKVRNLRQRLTARARHRCQ 1059
               Q   ++ R L ++   R + R Q
Sbjct: 703  RREQERREQERQLAEQERRREQERLQ 728


>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
          Length = 1217

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 67/277 (24%), Positives = 131/277 (47%), Gaps = 23/277 (8%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
           Q Q+ +++R   L+Y    Q + + +AK+D+   + E   +K   LR A++  R+ +   
Sbjct: 212 QYQKWDKMRR-ALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDI 270

Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRD 807
           E ++ + + +++A+K E +      Q +A R+    Q+ + E++ + L DE+      R 
Sbjct: 271 ERQVRELKTKISAMKEEKE------QLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRK 324

Query: 808 REIAATARDLEMRQLELESQKRLYEKNLTEN--QEALAKEMRADADAYRRKVDLEEHMFH 865
           R +    + LE  +   E QK L E     N  +E   + +   A A + + DL    + 
Sbjct: 325 RLLKERQKLLEKIE---EKQKELAETEPKFNSVKEKEERGIARLAQATQERTDL----YA 377

Query: 866 KLIEAGE-TQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCD-DLQRNKCYQEVAKL 923
           K     + T  ++  K IK+ L   +QA  +   QI ++HK   D +  + K  ++  KL
Sbjct: 378 KQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKL 437

Query: 924 LRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAK 960
                 +++  + A VEE  +K+ E + K+  L+S +
Sbjct: 438 -----DQDLNEVKARVEELDRKYYEVKNKKDELQSER 469


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 67/345 (19%), Positives = 154/345 (44%), Gaps = 32/345 (9%)

Query: 682  KFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRV--EDEAWYQKQELLRKAE-- 737
            K  V ++ + +       ++  + RQ + + Q +  +++   E E W +KQ  L++ E  
Sbjct: 358  KLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWK 417

Query: 738  ---------ETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ 788
                     E +RE+  Q EE+  +  +R  A K+EL+ +     +  RR+ L  Q++++
Sbjct: 418  KQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNRE 477

Query: 789  EMELRRLDDEIGRKVYM-------RDREIAATARDLEMRQLELESQKRLYEKNLTENQEA 841
            + E+ RL+ +  + +++       + ++I+   +D+ +++   +++  + +K   + +  
Sbjct: 478  QEEIVRLNSK-KKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQ-CDLEIM 535

Query: 842  LAKEMRADADAYRRKVDL---EEHMFH---KLIEAGETQSQKTQKVIKENLAKAEQACLN 895
              K+++ +   Y+ K+     E+ + +   K ++   T       + K++L K E+ C  
Sbjct: 536  EIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEK-EELCQR 594

Query: 896  TDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFR 955
               Q+ +L K+    L     +    K LRE    +   +  + + +  K KE E K   
Sbjct: 595  LKEQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLE 654

Query: 956  LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 1000
            L   KK   L D + +   + + N   E+      +++ R Q E+
Sbjct: 655  LMQKKK---LEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEK 696



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 71/315 (22%), Positives = 143/315 (45%), Gaps = 43/315 (13%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKA----EETRREM 743
           + QE+E  +  EL+   E+Q   + Q + ++++  +     KQEL R+     E  RR+ 
Sbjct: 410 ELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQE 469

Query: 744 LLQEEEKMIQQRQRLAAVKRELKVK-----EMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
           LL ++ +  ++  RL + K+ L ++       H Q + R + ++L++  Q+ EL  LD +
Sbjct: 470 LLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQ 529

Query: 799 IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQ------------------- 839
              ++ M  +++    ++ + + + L  +K+L  + +   Q                   
Sbjct: 530 CDLEI-MEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEK 588

Query: 840 EALAKEMRADADAYRR----KVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLN 895
           E L + ++   DA  +    K+   +   ++L E  ET +  TQ++  E L K ++  L 
Sbjct: 589 EELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETYN--TQQLALEQLYKIKRDKLK 646

Query: 896 T--DWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWK------ 947
                +++ + K+K +D    K  Q    L +EN RKE E     ++EE  + K      
Sbjct: 647 EIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEER 706

Query: 948 EAEGKEFRLRSAKKA 962
           +AE K+ + +   KA
Sbjct: 707 KAEEKQRKDKDTLKA 721


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 59/267 (22%), Positives = 129/267 (48%), Gaps = 25/267 (9%)

Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR--EMLLQEE 748
           E+E+IR +E     +RQ  E+M  + ++   ++E W QK+++  + E+ R+  E + ++E
Sbjct: 462 EQEKIREEE-----KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516

Query: 749 EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR-----KV 803
           EK+ +Q +++    RE + K    ++  R +    +++++  E  ++ +E  R     K+
Sbjct: 517 EKIREQEEKI----REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572

Query: 804 YMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHM 863
           + ++ +I    R+ E +    E + R  E+   E +E + K+     +    K+  +E  
Sbjct: 573 WRQEEKI----REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE-QEEKIQEQEEK 627

Query: 864 FHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKL 923
             +  E    Q + TQ+  ++   + E+ C     Q + + +Q+    ++ +  +E  K 
Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMC----EQEEKMQEQEETMWRQEEKIREQEKK 683

Query: 924 LRENRRKEIEIINAMVEEEAKKWKEAE 950
           +RE   K  E    M E+E K W++ E
Sbjct: 684 IREQEEKIREQEEMMQEQEEKMWEQEE 710



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 66/347 (19%), Positives = 164/347 (47%), Gaps = 42/347 (12%)

Query: 690  QERERIRNDELDYLRE-----RQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
            ++ E+IR  E + +RE     R+  E M  K ++ R ++E  ++K+E +R+ EE     +
Sbjct: 318  EQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE-----M 371

Query: 745  LQEEEKMIQQRQRLAAVKRELKVKE----MHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
            + E+E+ +++++ +   K E K++E    MH Q+  R +  K Q++++  E  +  ++  
Sbjct: 372  MWEKEEKMRRQEEMMWEKEE-KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 430

Query: 801  R------KVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---AKEMRADAD 851
            +      K+  ++ +I    + +  ++ ++  Q+++ E+   + QE +    +++    +
Sbjct: 431  KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490

Query: 852  AYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDL 911
             +R+K  + E    + I   E +  + ++ I+E   K  +       Q + + +Q+    
Sbjct: 491  IWRQKEKMHEQ--EEKIRKQEEKVWRQEEKIREQEEKIRE-------QEEKMWRQEEKIR 541

Query: 912  QRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEG-KEFRLRSAKKASALSDASR 970
            ++ + ++E  K+  + +  E E      E+E K W++ E  +E   +  ++   + +   
Sbjct: 542  EQEEMWREEEKMHEQEKIWEEE---KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598

Query: 971  KWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEM 1017
            K   +QE    +   E    ++E + Q EQ+     +  ++ +  EM
Sbjct: 599  K---RQEQEEKMWKQEEKIREQEEKIQ-EQEEKIREQEEKIREQEEM 641



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 52/284 (18%), Positives = 128/284 (45%), Gaps = 50/284 (17%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQ-----------RVEDEAWYQKQELLRKAEE 738
           ++ E+IR  E    R+ + + + + K+ +Q           R ++E W +++++  + + 
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559

Query: 739 TRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
              E   ++E+KM +Q +++   + ++  +E  +++   +R     Q+Q+E         
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR-----QEQEE--------- 605

Query: 799 IGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVD 858
              K++ ++ +I    R+ E +  E E + R  E+ + E +E   ++     +   +  +
Sbjct: 606 ---KMWKQEEKI----REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658

Query: 859 LEEHMFHKLIEAGETQSQKTQKV-IKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCY 917
            EE    K+ E  ET  ++ +K+  +E   + ++  +    ++    ++K  + +   C 
Sbjct: 659 QEE----KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714

Query: 918 QEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKK 961
           QE  + ++E   K       M  +E K W++    E RLR  ++
Sbjct: 715 QE--EKMQEQEEK-------MRRQEEKMWEQ----EVRLRQQEE 745



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 51/276 (18%), Positives = 130/276 (47%), Gaps = 27/276 (9%)

Query: 699 ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRL 758
           E D+L +   ++ + AK+  Q  E+E W +  +   +    + E + + EEK+ +Q +++
Sbjct: 266 EADHLGKE--LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323

Query: 759 AAVKRELKVKE---------MHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDRE 809
              + +++ +E         M  ++   RR  ++  +++E   R+ +    ++  MR +E
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383

Query: 810 IAATARDLEMRQLE--LESQKRLYEKNLTENQEALAKE----MRADADAYRRKVDLEEHM 863
                ++ ++R+LE  +  Q+++ E+     +E   +E       +A  +R++  + E  
Sbjct: 384 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 443

Query: 864 FHKLIEAGETQSQKTQKVIKENLAKAEQACLNTD--W-QIQSLHKQKCDDLQRNKCYQEV 920
             K+ E  +   ++ +K+ ++   + E+     +  W Q + +H+Q+    Q+ K +++ 
Sbjct: 444 -EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502

Query: 921 AKLLRENRR------KEIEIINAMVEEEAKKWKEAE 950
            K+ ++  +      K  E    + E+E K W++ E
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 41/197 (20%), Positives = 94/197 (47%), Gaps = 19/197 (9%)

Query: 686 DYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL 745
           D   ++ E+IR  E    R+ + + + + K  +Q  E++ W Q++++  + E+      +
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ--EEKMWKQEEKIREQEEK------I 621

Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME--LRRLDDEIGRKV 803
           QE+E+ I++++     + E+  ++         +  + ++  QE E  + R +++I R+ 
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI-REQ 680

Query: 804 YMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHM 863
             + RE     R+ E    E E +    E+ + E +E    +M+   +  RR+   EE M
Sbjct: 681 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE----KMQEQEEKMRRQ---EEKM 733

Query: 864 FHKLIEAGETQSQKTQK 880
           + + +   + Q +K Q+
Sbjct: 734 WEQEVRLRQ-QEEKMQE 749



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 61/345 (17%), Positives = 151/345 (43%), Gaps = 40/345 (11%)

Query: 680  YPKFIVDYQTQERERIRNDELDYLRERQT-----VEDMQAKVD-------QQRVEDEAWY 727
            Y   I D + +E+     ++L  +   ++     V++++ K++       QQ+++ EA +
Sbjct: 210  YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269

Query: 728  QKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD- 786
              +EL   + + + ++   E    + Q+Q     ++E K++E   +   +   ++ Q++ 
Sbjct: 270  LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329

Query: 787  --QQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAK 844
              +QE ++RR ++ +  K     R+        E    E E + R  E+ + E +E + +
Sbjct: 330  IREQEEKMRRQEEMMWEKEEKMRRQ--------EEMMWEKEEKMRRQEEMMWEKEEKMRR 381

Query: 845  EMRADADAYRRKVDLEEHMF-HKLIEAGETQSQKTQKVIKENLAKAEQACL-----NTDW 898
            +     +   +  +LEE M   + I   E + Q+ +K+ ++   + ++A +         
Sbjct: 382  QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441

Query: 899  QIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEII---NAMVEEEAKKWKEAEGKEFR 955
            Q + + +Q+    ++ +   E  K+  E +R+E E +      + E+ + W++ E    +
Sbjct: 442  QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501

Query: 956  LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 1000
                +K        + W  +++I    E  E    +EE  ++ E+
Sbjct: 502  EEKIRK-----QEEKVWRQEEKIR---EQEEKIREQEEKMWRQEE 538


>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
          Length = 1080

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 75/322 (23%), Positives = 147/322 (45%), Gaps = 49/322 (15%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQA--KVDQQRVEDEAWYQK-QELLRKAEETRREML 744
           Q  E +++ +++ + +      ED +   +V Q + + E   +K +EL+   E+ RRE  
Sbjct: 633 QLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKW 692

Query: 745 LQEEEKMIQQ----------RQRLAAVKREL-KVKEMH------LQDAARRRFLKLQQDQ 787
           + E+ K I++          ++ +A  K+E+ ++K +H        + A +R L+  ++ 
Sbjct: 693 ISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEEL 752

Query: 788 QEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---AK 844
           +E +L R  + +G++   R+R      + LE  Q  L+ Q++     + E +E L   A 
Sbjct: 753 RE-QLEREKEALGQQ--ERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAA 809

Query: 845 EMRADADAYRRKVDLEEHM--------FHKLIEAGETQSQKTQKVIKENLAKAEQACLNT 896
             RA+ +  R++++             F K  E  E + Q     +K+ L    QA    
Sbjct: 810 RQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQA---- 865

Query: 897 DWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEII-------NAMVEEEAKKWKEA 949
            W+     K++   L R    QE+ + +R+ R KEIE++        A+ +EE++K  E+
Sbjct: 866 -WEAGRTRKEEAWLLNRE---QELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAES 921

Query: 950 EGKEFRLRSAKKASALSDASRK 971
             K  R +   + S L  + RK
Sbjct: 922 RIKRLRDKYEAELSELEQSERK 943



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 65/292 (22%), Positives = 137/292 (46%), Gaps = 39/292 (13%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEK 750
            E E +++DE    R  +  E+++ ++++++   EA  Q++    +A +  ++ L QE+  
Sbjct: 731  EAELLQSDERASQRCLRQAEELREQLEREK---EALGQQER--ERARQRFQQHLEQEQWA 785

Query: 751  MIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME--------LRRLDDEIGRK 802
            + QQRQRL +   E   +E   Q AAR+R  +L++ +Q++E          R + E GR+
Sbjct: 786  LQQQRQRLYSEVAE--ERERLGQQAARQR-AELEELRQQLEESSSALTRALRAEFEKGRE 842

Query: 803  VYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEA--------LAKEMRADADAYR 854
               R  ++     +L   + +LE +++ +E   T  +EA        L +E+R   D   
Sbjct: 843  EQERRHQM-----ELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREEIRKGRD--- 894

Query: 855  RKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRN 914
            ++++L  H     +   + +S+K  +   + L    +A L+   Q +   +++C +L+  
Sbjct: 895  KEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQ 954

Query: 915  KCYQE-----VAKLLRENRR--KEIEIINAMVEEEAKKWKEAEGKEFRLRSA 959
                E     +  L+R+  R  ++ + +N  +  E     +   +EF  R A
Sbjct: 955  LGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLA 1006



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 5/180 (2%)

Query: 795 LDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYR 854
           L  E+   V     E+    + + + Q  L  Q+ L  + + E ++AL+++++   + Y 
Sbjct: 562 LGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYE 621

Query: 855 RKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRN 914
             +        +LIE  +  S+K + V+ E L + +Q C     Q Q+ H+ +   L+  
Sbjct: 622 ATIQRHLAFIDQLIEDKKVLSEKCEAVVAE-LKQEDQRCTERVAQAQAQHELEIKKLKEL 680

Query: 915 KCYQEVA---KLLRENRRKEIEIINAMVEEEAKKWKEAEGKEF-RLRSAKKASALSDASR 970
               E A   K + E  +K  E+    +E E +K      +E  RL+S  +A  L    R
Sbjct: 681 MSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDER 740



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 39/174 (22%), Positives = 75/174 (43%), Gaps = 21/174 (12%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLR-KAEETRREMLLQEE 748
            +E E+     +  LR++   E  + +  ++++++     K +L   + E  R + L++++
Sbjct: 913  EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQK 972

Query: 749  EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDR 808
            E+ ++  Q   AV  +L  +  +L    R+ F        E  L   ++E         R
Sbjct: 973  ERALEDAQ---AVNEQLSSERSNLAQVIRQEF--------EDRLAASEEET--------R 1013

Query: 809  EIAATARDLEMRQ-LELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEE 861
            +  A    L+ RQ LELE   R  +  L   +EA++        A +R   LEE
Sbjct: 1014 QAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEE 1067



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 8/101 (7%)

Query: 715 KVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQD 774
           +V+Q  V  + WY+ Q   R A   R E LLQ + +  +QRQR      E  + ++H Q 
Sbjct: 267 QVNQATVTIQRWYRHQVQRRGAGAARLEHLLQAKRE--EQRQR----SGEGTLLDLHQQK 320

Query: 775 AARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATAR 815
            A RR  K ++++     R    E+ +K  +R ++ +   R
Sbjct: 321 EAARR--KAREEKARQARRAAIQELQQKRALRAQKASTAER 359


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 70/343 (20%), Positives = 143/343 (41%), Gaps = 33/343 (9%)

Query: 690  QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE-- 747
            +E+  ++  +    +E     + Q ++++ R+E E   Q  E   +  E  +E L Q+  
Sbjct: 764  EEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLP 823

Query: 748  --EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYM 805
                +  Q +++LA + R+L  +E  L+ A R    + Q+  + +E    + E   K + 
Sbjct: 824  TLRHERSQLQEQLAQLSRQLSGREQELEQARR----EAQRQVEALERAAREKEALAKEH- 878

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFH 865
                +   A + E R L  E+ +   EK   E      +   A  +A R +++ E     
Sbjct: 879  AGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEG---Q 935

Query: 866  KLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLR 925
             L+ A ET + +   + ++ +A  E+A L+ +   Q L + +          +E    LR
Sbjct: 936  ALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAE----------REAQASLR 985

Query: 926  ENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHA 985
            E R    E +  +  E+   W+E E +  +L+S  +             ++E+ A +E  
Sbjct: 986  EQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE-----------QEELLARLEAE 1034

Query: 986  ENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRR 1028
            +    +E    Q E+D   L   S+   +  +  S + +L+ +
Sbjct: 1035 KEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEK 1077



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 52/247 (21%), Positives = 111/247 (44%), Gaps = 29/247 (11%)

Query: 685  VDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQK-QELLRKAEETRREM 743
            +D   Q     R        + QT+    A ++ QRVE E   Q+ +E+LR+ +E     
Sbjct: 1770 LDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAA 1829

Query: 744  L-----LQEEEKMIQQR--------QRLAAVKRELKVKEMHLQD---AARRRFLKLQQDQ 787
            L     LQ+E +++Q+R         +L A KRE++   + L+    A RR   K++++ 
Sbjct: 1830 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE- 1888

Query: 788  QEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMR 847
               +LR  +D +         +   T  +LE+ + + + Q+   +  + E   + A   +
Sbjct: 1889 ---KLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPA---Q 1942

Query: 848  ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQK 907
             + DA +++++L++      +E   +   +T++ ++       Q     + Q+ +L  Q 
Sbjct: 1943 LEVDAQQQQLELQQE-----VERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQL 1997

Query: 908  CDDLQRN 914
              +L+R+
Sbjct: 1998 QQELRRS 2004



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 64/310 (20%), Positives = 129/310 (41%), Gaps = 33/310 (10%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEE---TRREMLLQ 746
           +E +R+R+      RE+  +     +V QQ+ E+    Q++E L+ A+E    +R+ L +
Sbjct: 589 REVQRLRSANELLSREKSNLAH-SLQVAQQQAEELR--QEREKLQAAQEELRRQRDRLEE 645

Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMR 806
           E+E  +Q   R   V+REL+     L+    +R +  +      EL  + + + R    R
Sbjct: 646 EQEDAVQDGAR---VRRELERSHRQLEQLEGKRSVLAK------ELVEVREALSRATLQR 696

Query: 807 D------REIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLE 860
           D       E+A      E  ++ELE             Q++L+K    +    + K+DL 
Sbjct: 697 DMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 756

Query: 861 EHMFH-----KLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNK 915
             +         ++  + Q+++   V +E   + E+  L  +   Q L        Q  +
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 816

Query: 916 CYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLK 975
             ++    LR  R       + + E+ A+  ++  G+E  L  A++ +     + +   +
Sbjct: 817 ALEQQLPTLRHER-------SQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAR 869

Query: 976 QEINAAVEHA 985
           ++   A EHA
Sbjct: 870 EKEALAKEHA 879



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 40/177 (22%), Positives = 76/177 (42%), Gaps = 25/177 (14%)

Query: 690  QERERIRND---ELDYLRERQTVEDMQ-AKVDQQRVEDEAWYQKQELLRKAEETRREMLL 745
            QE ER R +   EL  LR +  + D +  ++ ++  E +    +  L  +AE+  R   L
Sbjct: 1269 QEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQG---RLALGERAEKESRRETL 1325

Query: 746  QEEEKMIQQRQRLAAVKRELKVKEMHLQD------AARRRFLKLQQDQQEMELRRLDDEI 799
               +++++    L  +++EL+V +  LQ+         RR L   ++ +  E ++LD   
Sbjct: 1326 GLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHAR 1385

Query: 800  GRKVYMRDREIAAT------------ARDLEMRQLELESQKRLYEKNLTENQEALAK 844
            G ++ +      A             A+ LE     +E Q+R  E  L   + AL +
Sbjct: 1386 GLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRR 1442


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 100/389 (25%), Positives = 168/389 (43%), Gaps = 52/389 (13%)

Query: 702  YLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAV 761
            +++E++ +ED  A+   Q  E+E   +    +R  +E     L +  +K  + RQ L   
Sbjct: 997  FIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056

Query: 762  KRELKVKEMHLQD-----AARRRFLKLQQDQQEMELR----RLDDEIGRK------VYMR 806
            KR+L  +   LQD      A+   LKLQ  ++E EL+    R DDE   K      V   
Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVREL 1116

Query: 807  DREIAATARDLEMRQL---ELESQKRLYEKNLTENQEALAKEMRADADA------YRRKV 857
              +IA    D E  +    + E QKR    +L+E  EAL  E+    D        R K 
Sbjct: 1117 QAQIAELQEDFESEKASRNKAEKQKR----DLSEELEALKTELEDTLDTTAAQQELRTKR 1172

Query: 858  DLEEHMFHKLIEAGETQSQKTQ------------KVIKENLAKAEQACLNTDWQIQSLHK 905
            + E     K +E  ET++ + Q            + + E L +A++   N +   Q L  
Sbjct: 1173 EQEVAELKKALEE-ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET 1231

Query: 906  QKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASAL 965
               +     K  Q+V K   E++RK+++   A V+E     K +EG   R+  A+KAS L
Sbjct: 1232 DNKELACEVKVLQQV-KAESEHKRKKLD---AQVQE--LHAKVSEGDRLRVELAEKASKL 1285

Query: 966  SDA--SRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMD--PST 1021
             +   +    L++     ++ A++    E  + Q+ Q+        +LN SS +      
Sbjct: 1286 QNELDNVSTLLEEAEKKGIKFAKDAASLES-QLQDTQELLQEETRQKLNLSSRIRQLEEE 1344

Query: 1022 QISLNRRAVEWDTTGQNLIKKVRNLRQRL 1050
            + SL  +  E +   +NL K+V  L+ +L
Sbjct: 1345 KNSLQEQQEEEEEARKNLEKQVLALQSQL 1373



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 94/463 (20%), Positives = 185/463 (39%), Gaps = 98/463 (21%)

Query: 676  VFNQYPKFIVDYQTQERERIRNDELDYLRERQT-----VEDMQAK----VDQQRVEDEAW 726
            VF +    +   + +E  + +++EL  ++E+QT     +E+M+ K    ++++ +  E  
Sbjct: 837  VFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQL 896

Query: 727  YQKQELLRKAEETR----------REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAA 776
              + EL  +AEE R           E+L   E ++ ++ +R   ++ E K  + H+QD  
Sbjct: 897  QAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLE 956

Query: 777  R--------RRFLKLQQDQQEMELRRLDDE-----------IGRKVYMRDREIAATAR-- 815
                     R+ L+L++   E +++++++E           I  K  M DR    +++  
Sbjct: 957  EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLA 1016

Query: 816  ---------------------DLEMR-------QLELESQKRLYEKNLTENQEALAKEMR 847
                                 DLE R       + ELE  KR  +   T+ Q+ +A E++
Sbjct: 1017 EEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA-ELQ 1075

Query: 848  ADADAYRRKVDLEEHMFHKLIEAGETQS---QKTQKVIKENLA----------------- 887
            A  D  + ++  +E      +  G+ ++       KV++E  A                 
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRN 1135

Query: 888  KAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWK 947
            KAE+   +   ++++L  +  D L      QE    LR  R +E+  +   +EEE K   
Sbjct: 1136 KAEKQKRDLSEELEALKTELEDTLDTTAAQQE----LRTKREQEVAELKKALEEETKN-H 1190

Query: 948  EAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPR 1007
            EA+ ++ R R    A+AL + S +    +   A +E  +     +      E       +
Sbjct: 1191 EAQIQDMRQR---HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247

Query: 1008 TSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRL 1050
                +   ++D   Q  L+ +  E D     L +K   L+  L
Sbjct: 1248 AESEHKRKKLDAQVQ-ELHAKVSEGDRLRVELAEKASKLQNEL 1289



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 78/355 (21%), Positives = 157/355 (44%), Gaps = 45/355 (12%)

Query: 696  RNDELDYLRERQT-VEDMQAKVDQQRVE-DEAWYQKQELLRKAEETRREM------LLQE 747
            +N+ L  +RE Q  + ++Q   + ++   ++A  QK++L  + E  + E+         +
Sbjct: 1106 KNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQ 1165

Query: 748  EEKMIQQRQRLAAVKR----ELKVKEMHLQDAARRRFLKLQQDQQEME-LRRLDDEIGRK 802
            +E   ++ Q +A +K+    E K  E  +QD  +R    L++  +++E  +R    + + 
Sbjct: 1166 QELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKN 1225

Query: 803  ---VYMRDREIAATARDLEMRQLELESQKRLYEKNLTE------NQEALAKEMRADADAY 853
               +   ++E+A   + L+  + E E +++  +  + E        + L  E+   A   
Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKL 1285

Query: 854  RRKVD-----LEEH-----MFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSL 903
            + ++D     LEE       F K   + E+Q Q TQ++++E   +     LN   +I+ L
Sbjct: 1286 QNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK----LNLSSRIRQL 1341

Query: 904  HKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKAS 963
             ++K + LQ  +  +E A   R+N  K++  + + + +  KK  +  G    L  AKK  
Sbjct: 1342 EEEK-NSLQEQQEEEEEA---RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKK-K 1396

Query: 964  ALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMD 1018
             L DA       +E   A +  E    K + R Q E D   +    Q   +S ++
Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLE----KTKNRLQQELDDLTVDLDHQRQVASNLE 1447



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 81/389 (20%), Positives = 168/389 (43%), Gaps = 46/389 (11%)

Query: 685  VDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
            +D+Q Q    +   +  + +     + + A+  ++R   EA  +++E    +     E  
Sbjct: 1436 LDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEA 1495

Query: 745  LQEEEKMIQQRQRLAAVKRELKV------KEMHLQDAARRRFLKLQQDQQEMELRRLDDE 798
            L+ +E+  +Q ++L A   +L        K +H  + ++R  L+ Q ++   +L  L+DE
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA-LEQQVEEMRTQLEELEDE 1554

Query: 799  IGR--------KVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKE--MRA 848
            +          +V M+  + A   RDL+ R  + E +KRL  K + E +  L  E   RA
Sbjct: 1555 LQATEDAKLRLEVNMQAMK-AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA 1613

Query: 849  DADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKC 908
             A A ++K++++       IEA      +  K +++  A+ +      D+Q + L + + 
Sbjct: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMK------DYQ-RELEEARA 1666

Query: 909  DDLQRNKCYQEVAKLLRENRRKEIEIINAMVE----EEAKKWKEAEGKEFR---LRSAKK 961
                R++ + +  +  ++ +  E EI+    E    E A++  E E  E       SA  
Sbjct: 1667 ---SRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1723

Query: 962  ASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPST 1021
             SAL D  R+      + A +   E    +E+   +   D     +T+   D+   + + 
Sbjct: 1724 KSALLDEKRR------LEARIAQLEEELEEEQSNMELLNDR--FRKTTLQVDTLNAELAA 1775

Query: 1022 QISLNRRAVEWDTTGQNLIKKVRNLRQRL 1050
            + S  +++   D   Q L ++ + L+ +L
Sbjct: 1776 ERSAAQKS---DNARQQLERQNKELKAKL 1801



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 66/313 (21%), Positives = 133/313 (42%), Gaps = 28/313 (8%)

Query: 685  VDYQTQERERIRNDELDYLRERQT-VEDMQAKVDQQRVE-DEAWYQKQELLRKAEETRRE 742
            ++ Q +   + R++ +  LR+ Q  ++D Q ++++ R   DE + Q +E  +K +    E
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688

Query: 743  MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG-- 800
            +L  +EE    +R R  A +   ++ +     A+ +  L  ++ + E  + +L++E+   
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748

Query: 801  -----------RKVYMR----DREIAA---TARDLEMRQLELESQKRLYEKNLTENQEAL 842
                       RK  ++    + E+AA    A+  +  + +LE Q +  +  L E + A+
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808

Query: 843  AKEMRADADAYRRKV-DLEEHMFHKLIE--AGETQSQKTQKVIKENLAKAEQACLNTDWQ 899
              + +A   A   K+  LEE +  +  E  A     ++T+K +KE   + E    + D  
Sbjct: 1809 KSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY 1868

Query: 900  IQSLHKQKCDDLQRNKCYQEV---AKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRL 956
             + + K      Q  +  +E    A     +RRK    ++   E      +E    + RL
Sbjct: 1869 KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRL 1928

Query: 957  RSAKKASALSDAS 969
            R     S  S  S
Sbjct: 1929 RRGGPISFSSSRS 1941


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 60/267 (22%), Positives = 128/267 (47%), Gaps = 18/267 (6%)

Query: 694 RIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR---EMLLQEEEK 750
           ++  +EL     +Q  E M  + ++ +  +E   +++E +R+ EE  R   EM+ ++EEK
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331

Query: 751 MIQQRQRLAAVKRELKVKE----MHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMR 806
           M +Q + +   ++E K++E    MH Q+  R +  K Q++++  E  +  ++   K++ +
Sbjct: 332 MRRQEEMMW--EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ-EAKMWRQ 388

Query: 807 DREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---AKEMRADADAYRRKVDLEEHM 863
           + +I    R+ E +  E E   +  E+ + E +E +    +EM+   +  RR+ +     
Sbjct: 389 EEKI----REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444

Query: 864 FHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKL 923
             K+ E  E   ++ + + ++     EQ     + + +   +++    Q  K  +E  K 
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK-IREQEKK 503

Query: 924 LRENRRKEIEIINAMVEEEAKKWKEAE 950
           +RE   K  E    M E+E K W++ E
Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWEQEE 530



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 62/317 (19%), Positives = 145/317 (45%), Gaps = 41/317 (12%)

Query: 699  ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRL 758
            E D+L +   ++ + AK+  Q  E+E W +  +              Q+EEKM +Q +++
Sbjct: 254  EADHLGKE--LQSVSAKLQAQVEENELWNRLNQ--------------QQEEKMWRQEEKI 297

Query: 759  AAVKRELKVKEMHLQDAARRRFLKLQQD---QQEMELRRLDDEIGRKVYMRDREIAATAR 815
               +RE K++E   +   +   ++ Q++   ++E ++RR ++ +  K   + RE+     
Sbjct: 298  Q--EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK-EEKIRELEEKMH 354

Query: 816  DLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQS 875
              E  ++  + +KR  E+ + E +    K    +A  +R++  + E    K+ E  E   
Sbjct: 355  --EQEKIREQEEKRQEEEKIREQE----KRQEQEAKMWRQEEKIREQE-EKIREQEEMMQ 407

Query: 876  QKTQKV--IKENLAKAEQACLNTD----WQIQSLHKQKCDDLQRNKCYQEVAKLLRENRR 929
            ++ +K+   +E + + E+     +     Q + + +Q+    ++ +  +E  ++++E   
Sbjct: 408  EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467

Query: 930  KEIEIINAMVEEEAKKWKEAE---GKEFRLRSAKKASALSD---ASRKWFLKQEINAAVE 983
            K  E    M E+EAK  ++ E    +E ++R  +K     +     ++  ++++     E
Sbjct: 468  KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527

Query: 984  HAENPCHKEEPRFQNEQ 1000
              E  C +EE   + E+
Sbjct: 528  QEEKMCEQEEKMQEQEE 544



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 51/286 (17%), Positives = 135/286 (47%), Gaps = 23/286 (8%)

Query: 725  AWYQKQELLRKAEETRREML--LQEEEKMIQQ-RQRLAAVKRELKVKEMHLQDAARRR-- 779
            A Y  Q  +++ E   R+++  L +  K   +  Q L+AV  + K  + ++++  + R  
Sbjct: 133  ALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDA 192

Query: 780  -FLKLQQDQ-QEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLY-EKNLT 836
              L+L ++   + EL+  + ++  K+ + + E +    +++  + +LE  K L  ++ L 
Sbjct: 193  LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 252

Query: 837  ENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNT 896
               + L KE+++ +   + +V+ E  ++++L +  E +  + ++ I+E   K ++     
Sbjct: 253  AEADHLGKELQSVSAKLQAQVE-ENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKI 311

Query: 897  DWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEA-KKWKEAEGKEFR 955
              Q + + +Q+    ++ +  +   +++ E   K  E+   M E+E  ++ +E   +E +
Sbjct: 312  REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371

Query: 956  LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
            +R  +K             +QE  A +   E    ++E + + +++
Sbjct: 372  IREQEK-------------RQEQEAKMWRQEEKIREQEEKIREQEE 404



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 25/145 (17%), Positives = 77/145 (53%), Gaps = 8/145 (5%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREM---LLQ 746
           ++ E ++  E    R+ + + + + K+ +Q   +E   +++E++++ EE   E    + +
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQ---EEKIREQEEMMQEQEEKMGEQEGKMCE 478

Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHL--QDAARRRFLKLQQDQQEMELRRLDDEIGRKVY 804
           +E KM +Q +++   + +++ +E  +  Q+   R   ++ Q+Q+E    + +    ++  
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538

Query: 805 MRDREIAATARDLEMRQLELESQKR 829
           M+++E     ++ +MR+ E+  +++
Sbjct: 539 MQEQEEKMRRQEEKMREQEVRLRQQ 563



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 24/108 (22%), Positives = 64/108 (59%), Gaps = 8/108 (7%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRRE---MLLQ 746
           QE+E    ++   + E++    MQ + ++ R ++E   ++++ +R+ EE  RE   M+ +
Sbjct: 463 QEQEEKMGEQEGKMCEQEA--KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520

Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHL---QDAARRRFLKLQQDQQEME 791
           +EEKM +Q +++   + +++ +E  +   ++  R + ++L+Q +++M+
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 25/122 (20%), Positives = 57/122 (46%), Gaps = 13/122 (10%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQR---VEDEAWYQKQE-LLRKAEETRREM-- 743
           ++ ++IR  E     + + +++ + K+ +Q     E EA  Q+QE  +R+ EE  RE   
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502

Query: 744 -------LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLD 796
                   ++E+E+M+Q+++     + E   ++         +  + ++  +E E+R   
Sbjct: 503 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562

Query: 797 DE 798
            E
Sbjct: 563 QE 564


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 82/366 (22%), Positives = 148/366 (40%), Gaps = 46/366 (12%)

Query: 682  KFIVDYQTQERERIRNDELDYLRERQTVEDMQAK----------VDQQRVEDEAWYQKQE 731
            K  V ++ ++RE      L+  + RQ + + Q K           +Q+R E E   Q+++
Sbjct: 345  KLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERK 404

Query: 732  L---LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ 788
                L K  E +RE+  Q EE+  ++ +R  A KREL+ ++  L+    RR   L Q  +
Sbjct: 405  RQLELEKQLEKQRELERQREEERRKEIERREAAKRELE-RQRQLEWERNRRQELLNQRNK 463

Query: 789  EMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQK---RLYEKNLTENQEALAKE 845
            E E     D +  K   +  E    A + +  QLE + Q    RL  +         ++E
Sbjct: 464  EQE-----DIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRE 518

Query: 846  MR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKV------------IKENLAKAEQA 892
            +R A+    ++++   + M  +LI   +  + + ++V            +K  L   E A
Sbjct: 519  LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578

Query: 893  CLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGK 952
              +   Q+  + K+    LQ    +    K LRE   K+       +E E  K KE E K
Sbjct: 579  RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERK 638

Query: 953  EFRLRSAKKAS--ALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 1010
               L   K+ +     +  ++W         +EH +     + PR  +E++      + +
Sbjct: 639  IIELEKQKEEAQRRAQERDKQW---------LEHVQQEDEHQRPRKLHEEEKLKREESVK 689

Query: 1011 LNDSSE 1016
              D  E
Sbjct: 690  KKDGEE 695



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 47/228 (20%), Positives = 107/228 (46%), Gaps = 21/228 (9%)

Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
           E +L++E++ ++++  +    ++ +  E    +  +RR   L+Q ++E E     +   +
Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ 391

Query: 802 KVYMRDREIAATARDLEM-----RQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK 856
           +   R+R+     R LE+     +Q ELE Q+    +   E +EA  +E+       +R+
Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELER-----QRQ 446

Query: 857 VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCD---DLQR 913
           ++ E +   +L+     Q  K Q+ I   + KA++  L  ++++++L+ +K      LQ 
Sbjct: 447 LEWERNRRQELL----NQRNKEQEDIV--VLKAKKKTL--EFELEALNDKKHQLEGKLQD 498

Query: 914 NKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKK 961
            +C     +   E+  K  E+  A +    ++ +E++    RL   K+
Sbjct: 499 IRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQ 546



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 12/118 (10%)

Query: 684 IVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
           I + Q +E   I N +    ++    E ++ K +Q+R   E   QK+E  R+A+E  ++ 
Sbjct: 602 IFNNQLKELREIHNKQQLQKQKSMEAERLKQK-EQERKIIELEKQKEEAQRRAQERDKQW 660

Query: 744 LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
           L   +++   QR R           ++H ++  +R     ++D +E   +   D++GR
Sbjct: 661 LEHVQQEDEHQRPR-----------KLHEEEKLKREESVKKKDGEEKGKQEAQDKLGR 707


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 82/366 (22%), Positives = 148/366 (40%), Gaps = 46/366 (12%)

Query: 682  KFIVDYQTQERERIRNDELDYLRERQTVEDMQAK----------VDQQRVEDEAWYQKQE 731
            K  V ++ ++RE      L+  + RQ + + Q K           +Q+R E E   Q+++
Sbjct: 345  KLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERK 404

Query: 732  L---LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ 788
                L K  E +RE+  Q EE+  ++ +R  A KREL+ ++  L+    RR   L Q  +
Sbjct: 405  RQLELEKQLEKQRELERQREEERRKEIERREAAKRELE-RQRQLEWERNRRQELLNQRNK 463

Query: 789  EMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQK---RLYEKNLTENQEALAKE 845
            E E     D +  K   +  E    A + +  QLE + Q    RL  +         ++E
Sbjct: 464  EQE-----DIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRE 518

Query: 846  MR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKV------------IKENLAKAEQA 892
            +R A+    ++++   + M  +LI   +  + + ++V            +K  L   E A
Sbjct: 519  LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578

Query: 893  CLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGK 952
              +   Q+  + K+    LQ    +    K LRE   K+       +E E  K KE E K
Sbjct: 579  RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERK 638

Query: 953  EFRLRSAKKAS--ALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 1010
               L   K+ +     +  ++W         +EH +     + PR  +E++      + +
Sbjct: 639  IIELEKQKEEAQRRAQERDKQW---------LEHVQQEDEHQRPRKLHEEEKLKREESVK 689

Query: 1011 LNDSSE 1016
              D  E
Sbjct: 690  KKDGEE 695



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 47/228 (20%), Positives = 107/228 (46%), Gaps = 21/228 (9%)

Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
           E +L++E++ ++++  +    ++ +  E    +  +RR   L+Q ++E E     +   +
Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQ 391

Query: 802 KVYMRDREIAATARDLEM-----RQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK 856
           +   R+R+     R LE+     +Q ELE Q+    +   E +EA  +E+       +R+
Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELER-----QRQ 446

Query: 857 VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCD---DLQR 913
           ++ E +   +L+     Q  K Q+ I   + KA++  L  ++++++L+ +K      LQ 
Sbjct: 447 LEWERNRRQELL----NQRNKEQEDIV--VLKAKKKTL--EFELEALNDKKHQLEGKLQD 498

Query: 914 NKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKK 961
            +C     +   E+  K  E+  A +    ++ +E++    RL   K+
Sbjct: 499 IRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQ 546



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 12/118 (10%)

Query: 684 IVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
           I + Q +E   I N +    ++    E ++ K +Q+R   E   QK+E  R+A+E  ++ 
Sbjct: 602 IFNNQLKELREIHNKQQLQKQKSMEAERLKQK-EQERKIIELEKQKEEAQRRAQERDKQW 660

Query: 744 LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
           L   +++   QR R           ++H ++  +R     ++D +E   +   D++GR
Sbjct: 661 LEHVQQEDEHQRPR-----------KLHEEEKLKREESVKKKDGEEKGKQEAQDKLGR 707


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 71/323 (21%), Positives = 142/323 (43%), Gaps = 51/323 (15%)

Query: 688 QTQERERIRNDELDYLRERQTVED---------MQAKVDQQRVEDEAWYQKQELLRKAEE 738
           + +ERER+R +E     ERQ +++          + K +++R  +E    K+E  R AEE
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369

Query: 739 TRREMLLQEEEKMIQQRQRLAAVK------RELKVKEMHLQDAARRRFL---KLQQDQ-Q 788
            +R    +EE+  +++++R   ++      +E K+K   ++     +++   K Q+D+ Q
Sbjct: 370 RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ 429

Query: 789 EMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYE------------KNLT 836
              L++  +E G KV  +  ++       +  +++ E  K+  E            K  T
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT 489

Query: 837 E----NQEALAKEMRADADAYRR-----KVDLEEHMFHKLIEAG---ETQSQKTQKVIKE 884
           E    N E +  +++   + + R      VD +E      +EAG   E   ++  +   E
Sbjct: 490 EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESE 549

Query: 885 NLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAK 944
              K +Q       +++ L K++    +R K  +E      E RRK+ E    + EEE K
Sbjct: 550 EFEKLKQKQQEAALELEELKKKR---EERRKVLEE-----EEQRRKQEEADRKLREEEEK 601

Query: 945 KWKEAEGKEFRLRSAKKASALSD 967
           +  + E +  R  +A+K   + +
Sbjct: 602 RRLKEEIERRRAEAAEKRQKMPE 624



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 81/379 (21%), Positives = 152/379 (40%), Gaps = 48/379 (12%)

Query: 686  DYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRV----------------------ED 723
            D +   RER R    + LR++Q  E +    DQ  V                      +D
Sbjct: 33   DEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDD 92

Query: 724  EAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKL 783
            EA +   E L + EE R++ L +  E+  +    +      L  + M    A      K 
Sbjct: 93   EAAF--LERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKE 150

Query: 784  QQDQQEMELRRLDD-EIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQ-EA 841
            ++ +   E   +++ E   K Y ++    A     E ++ E E +++    ++ ENQ E 
Sbjct: 151  EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEV 210

Query: 842  LAKEMRADA-------DAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKEN--LAKAEQA 892
            + +E   ++            ++  EE    +  E G  +    +K+ +E+   A+AE+A
Sbjct: 211  MVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERA 270

Query: 893  CLNTD--WQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
             L  +   +I++   +K  D +R +   E     +E  R+E E    M EEE +  +E +
Sbjct: 271  RLEAEERERIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQ 329

Query: 951  G-KEFRLRSAKKASALSD-----ASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSC 1004
              KE   R+A++   + +     A  +  +K+E   A E  +    +EE + + E+    
Sbjct: 330  RIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK-- 387

Query: 1005 LPRTSQLNDSSEMDPSTQI 1023
              R  QL +       T+I
Sbjct: 388  --RNKQLEEKKHAMQETKI 404



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 66/323 (20%), Positives = 130/323 (40%), Gaps = 20/323 (6%)

Query: 738  ETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
            E RRE+  Q+ E+M  + +R+A  + +   +E   +   R R  +L+Q Q+E  L ++ D
Sbjct: 5    ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64

Query: 798  --EIGRKVYMRDREIAATARDLEMRQLE----LESQKRLYEKNLTENQEALAKEMRADAD 851
              E+  +  + D E   T  + ++   +    LE   R  E+     QEAL ++   D  
Sbjct: 65   QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPT 124

Query: 852  AYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDL 911
                 + L      + ++    +++ T+K  K    +       T+   +S  K    D 
Sbjct: 125  ITDASLSLPS----RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180

Query: 912  QRNKCYQEVAKLLRENRRKEIEI----INAMVEEEAKKWKEAEGKEFRLRSAKKASALSD 967
            + NK   +  +   E + K   I    +  MVEE+  + +E    E  + S K     S+
Sbjct: 181  EENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE----ETVVMSLKNGQISSE 236

Query: 968  ASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNR 1027
              ++   +++ +  + H E    +EE + + E + + L    +    +E D        R
Sbjct: 237  EPKQEEEREQGSDEISHHEK--MEEEDKERAEAERARLEAEERERIKAEQDKKIADERAR 294

Query: 1028 RAVEWDTTGQNLIKKVRNLRQRL 1050
               E     Q   ++    R+R+
Sbjct: 295  IEAEEKAAAQERERREAEERERM 317



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 67/327 (20%), Positives = 137/327 (41%), Gaps = 30/327 (9%)

Query: 688 QTQERERIRNDELDYL---RERQTVEDMQAKVDQQRVE-DEAWYQKQELLRKAEETRREM 743
           + +ERERI+ ++   +   R R   E+  A  +++R E +E    ++E  R AEE  R+ 
Sbjct: 273 EAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEE--RQR 330

Query: 744 LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKV 803
           + +EE++  ++RQR+   ++    +   +++  +R   + Q+ + E E +   +E  R  
Sbjct: 331 IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNK 390

Query: 804 YMRDREIAATARDLEMRQLELESQ-KRLYEKNLTEN--QEALAK----EMRADADAYRRK 856
            + +++ A     ++  ++E + + K + EK   E+  Q A+ K    E      A R K
Sbjct: 391 QLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK 450

Query: 857 VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKC 916
           +  ++  F K       +  K +K+ K+   K E        +  +  K +  +   +K 
Sbjct: 451 LQEDKPTFKK-------EEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 503

Query: 917 YQEVAKLLRENRRKEIEIINA----------MVEEEAKKWKEAEGKEFRLRSAKKASALS 966
                   R   R  ++   A           +EE  ++  E E +EF     K+  A  
Sbjct: 504 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL 563

Query: 967 DASRKWFLKQEINAAVEHAENPCHKEE 993
           +       ++E    +E  E    +EE
Sbjct: 564 ELEELKKKREERRKVLEEEEQRRKQEE 590



 Score = 37.4 bits (85), Expect = 0.076
 Identities = 37/141 (26%), Positives = 63/141 (44%), Gaps = 9/141 (6%)

Query: 713 QAKVDQQRVED----EAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVK 768
           +A VD +  E     EA  + +EL R+  ET  E    E EK+ Q++Q  A    ELK K
Sbjct: 516 RASVDTKEAEGAPQVEAGKRLEELRRRRGETESE----EFEKLKQKQQEAALELEELKKK 571

Query: 769 EMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQK 828
               +        + +Q++ + +LR  +++   K  +  R   A  +  +M +  L   K
Sbjct: 572 REERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 631

Query: 829 RLYEKNLTENQEALAKEMRAD 849
           + + K  T    +L  E RA+
Sbjct: 632 KPF-KCFTPKGSSLKIEERAE 651



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 42/210 (20%), Positives = 92/210 (43%), Gaps = 17/210 (8%)

Query: 693 ERIRNDELDYLRERQTVEDMQAKVDQQRV---EDEAWYQKQELLRKAEETRREMLLQEEE 749
           ++ + D+L     ++  E+   KV  +R    ED+  ++K+E+  K E+ +++   +EE 
Sbjct: 421 KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEI--KDEKIKKDKEPKEEV 478

Query: 750 KMIQQRQR-LAAVKRE----LKVKEMHLQDAARRRFLKLQQDQQEMEL-------RRLDD 797
           K    R++    VK +    +  K  H ++   R   +   D +E E        +RL++
Sbjct: 479 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 538

Query: 798 EIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKV 857
              R+      E     +  +   LELE  K+  E+     +E   +  + +AD   R+ 
Sbjct: 539 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598

Query: 858 DLEEHMFHKLIEAGETQSQKTQKVIKENLA 887
           + +  +  ++       ++K QK+ ++ L+
Sbjct: 599 EEKRRLKEEIERRRAEAAEKRQKMPEDGLS 628


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 50/236 (21%), Positives = 120/236 (50%), Gaps = 26/236 (11%)

Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR--EMLLQEE 748
           E+E+IR +E     +RQ  E+M  + ++ R ++E W QK+++  + E+ R+  E + ++E
Sbjct: 509 EQEKIREEE-----KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563

Query: 749 EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEM-ELRRLDDEIGRKVYMRD 807
           EKM  Q +++    RE + K    ++  R +  K+++ ++++ E   +  E   K+  ++
Sbjct: 564 EKMHDQEEKI----REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619

Query: 808 REIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKL 867
            ++     + E +  E E + R  E+ + E +    K++R   +  R + ++ +    K+
Sbjct: 620 EKMC----EQEEKMQEQEEKMRRQEEKIREQE----KKIREQEEKIREQEEMMQEQEEKM 671

Query: 868 IEAGETQSQKTQKV--IKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVA 921
            E  E   ++ +K+   +E + + E+      W+ +   +Q+ + +Q ++ + E A
Sbjct: 672 WEQEEKMCEQEEKMQEQEEKMRRQEEKM----WEQEVRLRQQEEKMQEHQEHLEAA 723



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 60/325 (18%), Positives = 152/325 (46%), Gaps = 27/325 (8%)

Query: 690  QERERIRNDELDYLRE-----RQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
            ++ E+IR  E + +RE     R+  E M  K ++ R ++E  ++K+E +R+ EE     +
Sbjct: 379  EQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE-----M 432

Query: 745  LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVY 804
            + E+E+ I++ +     + +++ +E   Q+  +   ++ Q+ +QE E +    E   K+ 
Sbjct: 433  MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK---IREQEKRQEQEAKMWRQE--EKIR 487

Query: 805  MRDREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---AKEMRADADAYRRKVDLEE 861
             ++ +I      +  ++ ++  Q+++ E+   + QE +    +++R   + +R+K  + E
Sbjct: 488  EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547

Query: 862  HMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVA 921
                + I   E +  + ++ + +   K  +       Q + + +Q+    ++ +  +E  
Sbjct: 548  Q--EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605

Query: 922  KLLRENRRKEIEIINAMVEEEAKKWKEAE---GKEFRLRSAKKASALSD---ASRKWFLK 975
            ++ +E   K  E    M E+E K  ++ E    +E ++R  +K     +     ++  ++
Sbjct: 606  EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665

Query: 976  QEINAAVEHAENPCHKEEPRFQNEQ 1000
            ++     E  E  C +EE   + E+
Sbjct: 666  EQEEKMWEQEEKMCEQEEKMQEQEE 690



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 60/317 (18%), Positives = 145/317 (45%), Gaps = 24/317 (7%)

Query: 699  ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRL 758
            E D+L +   ++ + AK+  Q  E+E W +  +   +    + E + + EEK+ +Q +++
Sbjct: 327  EADHLGKE--LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384

Query: 759  AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLE 818
               ++E K++E   Q+   RR  ++  +++E   R+ +    ++  MR +E     ++ +
Sbjct: 385  R--EQEEKIRE---QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439

Query: 819  MRQLE--LESQKRLYEKNLTENQEALAKE----MRADADAYRRKVDLEEHMFHKLIEAGE 872
            +R+LE  +  Q+++ E+     +E   +E       +A  +R++  + E    K+ E  E
Sbjct: 440  IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-EKIREQEE 498

Query: 873  TQSQKTQKVIKENLAKAEQACLNTD--W-QIQSLHKQKCDDLQRNKCYQEVAKLLRENRR 929
               ++ +K+ ++   + E+     +  W Q + + +Q+    Q+ K +++  K+ ++  +
Sbjct: 499  KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558

Query: 930  ------KEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVE 983
                  K  +    + E+E K W++ E    +    ++         +   +QE     E
Sbjct: 559  MWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG-E 617

Query: 984  HAENPCHKEEPRFQNEQ 1000
              E  C +EE   + E+
Sbjct: 618  QEEKMCEQEEKMQEQEE 634



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 31/114 (27%), Positives = 71/114 (62%), Gaps = 11/114 (9%)

Query: 689 TQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRRE---MLL 745
           TQE+E    ++ + + E++  E MQ + ++ R ++E   ++++ +R+ EE  RE   M+ 
Sbjct: 608 TQEQEEKMGEQEEKMCEQE--EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665

Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEI 799
           ++EEKM +Q +++   ++E K++E   ++  RR+  K+   +QE+ LR+ ++++
Sbjct: 666 EQEEKMWEQEEKMC--EQEEKMQEQ--EEKMRRQEEKMW--EQEVRLRQQEEKM 713



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 50/294 (17%), Positives = 134/294 (45%), Gaps = 18/294 (6%)

Query: 725  AWYQKQELLRKAEETRREML--LQEEEKMIQQ-RQRLAAVKRELKVKEMHLQDAARRR-- 779
            A Y  Q  +++ E   R+++  L +  K   +  Q L+AV  + K  + ++++  + R  
Sbjct: 206  ALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDA 265

Query: 780  -FLKLQQDQ-QEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLY-EKNLT 836
              L+L ++   + EL+  + ++  K+ + + E +    +++  + +LE  K L  ++ L 
Sbjct: 266  LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 325

Query: 837  ENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNT 896
               + L KE+++ +   + +V+ E  ++++L +  E +  + ++ I+E   K ++     
Sbjct: 326  AEADHLGKELQSVSAKLQAQVE-ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384

Query: 897  DWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEG----- 951
              Q + + +Q+    ++ +   E  + +R       E    M  +E   W++ E      
Sbjct: 385  REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444

Query: 952  ----KEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
                ++ ++R  ++     +  R+   +QE  A +   E    ++E + + +++
Sbjct: 445  EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498


>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
          Length = 1044

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 69/294 (23%), Positives = 129/294 (43%), Gaps = 29/294 (9%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQA--KVDQQRVEDEAWYQK-QELLRKAEETRREML 744
           Q  E +++ +++ + +      ED +   +V Q + + E   +K +EL+   E+ RRE  
Sbjct: 633 QLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKW 692

Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVY 804
           + E+ K I++           K+   H Q+  R + L       E EL + D+   ++  
Sbjct: 693 ISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSL------HEAELLQSDERASQRC- 745

Query: 805 MRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMF 864
           +R  E      + E   L  + ++R  ++   E +E L +++   + A  R +  E   F
Sbjct: 746 LRQAEELREQLEREKEALGQQERERARQRQRAELEE-LRQQLEESSSALTRALRAE---F 801

Query: 865 HKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLL 924
            K  E  E + Q     +K+ L    QA     W+     K++   L R    QE+ + +
Sbjct: 802 EKGREEQERRHQMELNTLKQQLELERQA-----WEAGRTRKEEAWLLNRE---QELREEI 853

Query: 925 RENRRKEIEII-------NAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRK 971
           R+ R KEIE++        A+ +EE++K  E+  K  R +   + S L  + RK
Sbjct: 854 RKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERK 907



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 82/334 (24%), Positives = 143/334 (42%), Gaps = 64/334 (19%)

Query: 704  RERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETR------REMLLQEEEKMIQQRQR 757
            R +Q V  +++  + + ++ +     Q  LR+AEE R      +E L Q+E +  +QRQR
Sbjct: 718  RHKQEVRRLKSLHEAELLQSDE-RASQRCLRQAEELREQLEREKEALGQQERERARQRQR 776

Query: 758  --LAAVKRELKVKEMHLQDAARRRFLKLQQDQ------------QEMELRRLDDEIGRK- 802
              L  ++++L+     L  A R  F K +++Q            Q++EL R   E GR  
Sbjct: 777  AELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTR 836

Query: 803  -----VYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKV 857
                 +  R++E+    R    +++EL   +   +  L + +   A E R      + + 
Sbjct: 837  KEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEA 896

Query: 858  DLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCY 917
            +L E      +E  E + Q+    +K  L +AE      + ++Q L +QK   L+  +  
Sbjct: 897  ELSE------LEQSERKLQERCSELKGQLGEAE----GENLRLQGLVRQKERALEDAQAV 946

Query: 918  QEVAKLLRENR----RKEIEIINAMVEEEAKKWK------------EAEGKEFRLRS--A 959
             E     R N     R+E E   A  EEE ++ K            E E    R+++  A
Sbjct: 947  NEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEVHRRVKTALA 1006

Query: 960  KKASALSDASRKWFLKQEINAAVEHAENPCHKEE 993
            +K  A+S       L+ +  AAV+ A+   H EE
Sbjct: 1007 RKEEAVSS------LRTQHEAAVKRAD---HLEE 1031



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 57/267 (21%), Positives = 113/267 (42%), Gaps = 27/267 (10%)

Query: 795  LDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYR 854
            L  E+   V     E+    + + + Q  L  Q+ L  + + E ++AL+++++   + Y 
Sbjct: 562  LGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYE 621

Query: 855  RKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDL--- 911
              +        +LIE  +  S+K + V+ E L + +Q C     Q Q+ H+ +   L   
Sbjct: 622  ATIQRHLAFIDQLIEDKKVLSEKCEAVVAE-LKQEDQRCTERVAQAQAQHELEIKKLKEL 680

Query: 912  -------QRNKCYQEVAKLLRE----NRRKEIEIINAMVEEEAKKWK---EAEGKEFRLR 957
                   +R K   E  K ++E        EI+ + A  ++E ++ K   EAE  +   R
Sbjct: 681  MSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDER 740

Query: 958  SAKKASALSDASRKWFLKQEINAAVEHAENPCHK-----EEPRFQNEQDSSCLPRTSQLN 1012
            ++++    ++  R+   +++     +  E    +     EE R Q E+ SS L R  +  
Sbjct: 741  ASQRCLRQAEELREQLEREKEALGQQERERARQRQRAELEELRQQLEESSSALTRALR-- 798

Query: 1013 DSSEMDPSTQISLNRRAVEWDTTGQNL 1039
              +E +   +    R  +E +T  Q L
Sbjct: 799  --AEFEKGREEQERRHQMELNTLKQQL 823



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 8/101 (7%)

Query: 715 KVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQD 774
           +V+Q  V  + WY+ Q   R A   R E LLQ + +  +QRQR      E  + ++H Q 
Sbjct: 267 QVNQATVTIQRWYRHQVQRRGAGAARLEHLLQAKRE--EQRQR----SGEGTLLDLHQQK 320

Query: 775 AARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATAR 815
            A RR  K ++++     R    E+ +K  +R ++ +   R
Sbjct: 321 EAARR--KAREEKARQARRAAIQELQQKRALRAQKASTAER 359


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 668

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 56/323 (17%), Positives = 153/323 (47%), Gaps = 25/323 (7%)

Query: 690  QERERIRNDELDYLRE-----RQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
            ++ E+IR  E + +RE     R+  E M  K ++ R ++E  ++K+E +R+ EE     +
Sbjct: 318  EQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE-----M 371

Query: 745  LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVY 804
            + E+E+ I++ +     + +++ +E   Q+  +   ++ Q+ +QE E +    E   K+ 
Sbjct: 372  MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK---IREQEKRQEQEAKMWRQE--EKIR 426

Query: 805  MRDREIAATARDLEMRQLELESQKRLYEKNLTENQEAL---AKEMRADADAYRRKVDLEE 861
             ++ +I    + +  ++ ++  Q+++ E+   + QE +    +++R   + +R+K  + E
Sbjct: 427  EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486

Query: 862  HMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVA 921
                +  E    + ++     +E + + E+       Q + + +Q+    ++ +  +E  
Sbjct: 487  QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR---QEEKIREQEEKIREQEEKIREQE 543

Query: 922  KLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAA 981
            ++++E   K  E    M E+E  + +E + +E   +  ++   + +   K + ++E    
Sbjct: 544  EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE---K 600

Query: 982  VEHAENPCHKEEPRFQNEQDSSC 1004
            +   E    ++E +   +++  C
Sbjct: 601  IREQEEMMQEQEEKMWEQEEKMC 623



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 38/245 (15%), Positives = 117/245 (47%), Gaps = 16/245 (6%)

Query: 690 QERERIRNDELDYLRERQTVEDMQA--KVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
           ++ E+IR  E    R+ + + + +   + ++++ ++E W Q++++  + E  R++  + E
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486

Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIGRKVYMR 806
           +EK+ +Q +++   + ++  +E  +++   + + + ++  +QE ++R  +++I      R
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI------R 540

Query: 807 DREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHK 866
           ++E     ++ +M     E ++++ E+     QE   +E        + K+  +E    +
Sbjct: 541 EQEEMMQEQEEKMG----EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596

Query: 867 LIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRE 926
             E    Q +  Q+  ++   + E+ C   +   +   K +    Q  K +++  +L ++
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR---RQEEKMWEQEVRLRQQ 653

Query: 927 NRRKE 931
             + +
Sbjct: 654 EEKMQ 658



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 36/273 (13%)

Query: 699 ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRL 758
           E D+L +   ++ + AK+  Q  E+E W +  +   +    + E + + EEK+ +Q +++
Sbjct: 266 EADHLGKE--LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323

Query: 759 AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLE 818
              + +++ +E  ++      + K ++ +++ E+    +E  R++     E     R+LE
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383

Query: 819 MRQLELE-----SQKRLYEKNLTE---NQEALAKEMRADADAYRRKVDLEE--------- 861
            +  E E      +KR  E+ + E    QE  AK  R +     ++  + E         
Sbjct: 384 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443

Query: 862 ---HMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDW-QIQSLHKQKCDDLQRNKCY 917
              H   K+ E  + Q Q+     +E + + E+      W Q + +H+Q+    Q  K +
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI-----WRQKEKMHEQEKIRKQEEKVW 498

Query: 918 QEVAKLLRENRRKEIEIINAMVEEEAKKWKEAE 950
           ++  K+  +  +        + E+E K W++ E
Sbjct: 499 RQEEKMHDQEEK--------IREQEEKMWRQEE 523



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/360 (18%), Positives = 157/360 (43%), Gaps = 46/360 (12%)

Query: 680  YPKFIVDYQTQERERIRNDELDYLRERQT-----VEDMQAKVD-------QQRVEDEAWY 727
            Y   I D + +E+     ++L  +   ++     V++++ K++       QQ+++ EA +
Sbjct: 210  YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269

Query: 728  QKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQ 787
              +EL   + + + ++   E    + Q+Q     ++E K++E            K+Q  +
Sbjct: 270  LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE---------EKIQ--E 318

Query: 788  QEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAK--E 845
            QE ++R  +++I        RE     R  E    E E + R  E+ + E +E + +  E
Sbjct: 319  QEEKIREQEEKI--------REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370

Query: 846  MRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACL-----NTDWQI 900
            M  + +   R+++ + H   K+ E  E + Q+ +K+ ++   + ++A +         Q 
Sbjct: 371  MMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429

Query: 901  QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEII---NAMVEEEAKKWKEAEGKEFRLR 957
            + + +Q+    ++ +   E  K+  E +R+E E +      + E+ + W++ E    + +
Sbjct: 430  EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK 489

Query: 958  SAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEM 1017
              K+   +     K   ++E    +   E    ++E + + EQ+     +  ++ +  EM
Sbjct: 490  IRKQEEKVWRQEEKMHDQEE---KIREQEEKMWRQEEKIR-EQEEKIREQEEKIREQEEM 545



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 20/88 (22%), Positives = 50/88 (56%), Gaps = 4/88 (4%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAE--ETRREMLLQE 747
           +++E+IR  E     + + + + +  + +Q  E++ W Q++++  + E  + + E + ++
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639

Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDA 775
           EEKM +Q  RL   + +++  + HL+ A
Sbjct: 640 EEKMWEQEVRLRQQEEKMQEHQEHLEAA 667


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 53/222 (23%), Positives = 116/222 (52%), Gaps = 23/222 (10%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
           ++ E+IR  E    R+ + + +   K+ +Q  E+E W Q +E +R+ EE R+E + ++E+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQ--EEEMWRQ-EEKIREQEEKRQEKMWRQEK 413

Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDRE 809
           KM +Q +++    RE + +EM  Q+   R   ++ QDQ+E +LR ++++      M++ E
Sbjct: 414 KMREQDEKI----RE-QEEEMWRQEEKIRELEEMMQDQEE-KLREVEEK------MQEEE 461

Query: 810 IAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HK 866
                ++ ++++ E + Q+   ++  T  QE L K+     +   +    EE M+    K
Sbjct: 462 EKMQEQEEKIQRQEEKIQE---QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518

Query: 867 LIEAGETQSQKTQKVIKE--NLAKAEQACLNTDWQIQSLHKQ 906
           + E  E   ++ +K+ ++   L + E+     + ++Q L ++
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 78/375 (20%), Positives = 167/375 (44%), Gaps = 55/375 (14%)

Query: 649  LMETTPTDIHPDSMLNVFVALTKGQ-YPVFNQYPKFIVDYQTQER-----ERIRNDELDY 702
            L+E T    H   M      LTK +  P    Y   I D + +E+     E++R  E + 
Sbjct: 175  LLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEK 234

Query: 703  LRERQTVEDMQAKVD-------QQRVEDEAWYQKQELLR-------KAEETRREMLL--Q 746
               +  V+D++ K++       QQ+++ EA    +EL         + EE     LL  Q
Sbjct: 235  SEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQ 294

Query: 747  EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIGRKVYM 805
            +EEKM +Q +++   + ++  +E+ +++   + + + ++  +QE ++R  +D    K++ 
Sbjct: 295  QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED----KMWR 350

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFH 865
            ++ +I    R+ E +  E E +    E+ + E  E + ++              EE M+ 
Sbjct: 351  QEEKI----REQEEKIREQEEKMWRQEEKIREQDEKIQEQ--------------EEEMWR 392

Query: 866  KLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLR 925
            +  +  E + ++ +K+ ++     EQ         + + +Q+ +  ++ +  +E+ ++++
Sbjct: 393  QEEKIREQEEKRQEKMWRQEKKMREQD--------EKIREQEEEMWRQEEKIRELEEMMQ 444

Query: 926  ENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHA 985
            +   K  E+   M EEE +K +E E K  R     +        ++  LKQE     E  
Sbjct: 445  DQEEKLREVEEKMQEEE-EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE-EKIWEQE 502

Query: 986  ENPCHKEEPRFQNEQ 1000
            E    +EE  ++ E+
Sbjct: 503  EKMWRQEEKMWEQEE 517



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 9/85 (10%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRV----EDEAWYQKQELLRKAEETRREM 743
           Q QE +  R ++L  L++ + + + + K+ +Q      ++E   +++E +++ EE  RE 
Sbjct: 479 QEQEEKTWRQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536

Query: 744 ---LLQEEEKMIQQRQRLAAVKREL 765
              L Q+EEKM +Q  RL  ++  L
Sbjct: 537 EVRLWQQEEKMQEQEVRLQELEERL 561


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 53/222 (23%), Positives = 116/222 (52%), Gaps = 23/222 (10%)

Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
           ++ E+IR  E    R+ + + +   K+ +Q  E+E W Q +E +R+ EE R+E + ++E+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQ--EEEMWRQ-EEKIREQEEKRQEKMWRQEK 413

Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDRE 809
           KM +Q +++    RE + +EM  Q+   R   ++ QDQ+E +LR ++++      M++ E
Sbjct: 414 KMREQDEKI----RE-QEEEMWRQEEKIRELEEMMQDQEE-KLREVEEK------MQEEE 461

Query: 810 IAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HK 866
                ++ ++++ E + Q+   ++  T  QE L K+     +   +    EE M+    K
Sbjct: 462 EKMQEQEEKIQRQEEKIQE---QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518

Query: 867 LIEAGETQSQKTQKVIKE--NLAKAEQACLNTDWQIQSLHKQ 906
           + E  E   ++ +K+ ++   L + E+     + ++Q L ++
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 64/336 (19%), Positives = 154/336 (45%), Gaps = 40/336 (11%)

Query: 680  YPKFIVDYQTQER-----ERIRNDELDYLRERQTVEDMQAKVD-------QQRVEDEAWY 727
            Y   I D + +E+     E++R  E +    +  V+D++ K++       QQ+++ EA  
Sbjct: 207  YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266

Query: 728  QKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQ 787
              +EL   + + + ++   E   ++ Q+Q     ++E K++E            + +  +
Sbjct: 267  LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ-----------EEKMCE 315

Query: 788  QEMELRRLDDEIGR---KVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAK 844
            QE+++R  ++++ R   K++ ++ +I    R+ E +    E + R  E+ + E +E + +
Sbjct: 316  QELKIREQEEKMWRQEEKMHEQEEKI----REQEDKMWRQEEKIREQEEKIREQEEKMWR 371

Query: 845  EMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLH 904
            +     +   +  + EE M+ +  +  E + ++ +K+ ++     EQ         + + 
Sbjct: 372  QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD--------EKIR 423

Query: 905  KQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASA 964
            +Q+ +  ++ +  +E+ +++++   K  E+   M EEE +K +E E K  R     +   
Sbjct: 424  EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-EKMQEQEEKIQRQEEKIQEQE 482

Query: 965  LSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 1000
                 ++  LKQE     E  E    +EE  ++ E+
Sbjct: 483  EKTWRQEKLLKQE-EKIWEQEEKMWRQEEKMWEQEE 517



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 45/182 (24%), Positives = 89/182 (48%), Gaps = 27/182 (14%)

Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVED--------EAWYQK------QELL 733
           Q QE E  R +E    +E +  E M  +  + R +D        E W Q+      +E++
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443

Query: 734 RKAEETRREM---LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ---DQ 787
           +  EE  RE+   + +EEEKM +Q +++   ++E K++E   +   + + LK ++   +Q
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQ--RQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501

Query: 788 QEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLEL-----ESQKRLYEKNLTENQEAL 842
           +E   R+ +    ++  M+++E     ++ +MR+ E+     E + +  E  L E +E L
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561

Query: 843 AK 844
            K
Sbjct: 562 GK 563



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 52/260 (20%), Positives = 108/260 (41%), Gaps = 33/260 (12%)

Query: 742  EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
            E L +E + +  +  R      ELK K   LQ+                +LR ++ E   
Sbjct: 193  EKLTKERDALSLELYRNTITDEELKEKNAELQE----------------KLRLVESE--- 233

Query: 802  KVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEE 861
                   EI    +DL+ R+LE  +Q  L ++ L    + L KE+++ +   + +V+ E 
Sbjct: 234  -----KSEIQLNVKDLK-RKLE-RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-EN 285

Query: 862  HMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVA 921
             +++ L +  E +  + ++ I+E   K  +  L    Q + + +Q+    ++ +  +E  
Sbjct: 286  ELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE 345

Query: 922  KLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAA 981
              +     K  E    + E+E K W++ E    ++R  +           W  +++I   
Sbjct: 346  DKMWRQEEKIREQEEKIREQEEKMWRQEE----KIRE-QDEKIQEQEEEMWRQEEKIREQ 400

Query: 982  VEHAENPCHKEEPRFQNEQD 1001
             E  +    ++E + + EQD
Sbjct: 401  EEKRQEKMWRQEKKMR-EQD 419


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 83/352 (23%), Positives = 156/352 (44%), Gaps = 45/352 (12%)

Query: 678  NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
            +QY KFI +   +  E  R  E     ER+ + +++A +++QR   EA  Q K +  R+A
Sbjct: 1331 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1390

Query: 737  EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
            +E ++ M   +++ EE  +  +Q+  +++ EL    +  E  +Q      +AA R  L++
Sbjct: 1391 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1450

Query: 784  QQD------QQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTE 837
            +++      Q E   R+     G    +R R   A A+  + ++ E E  +R  +     
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-EAERLRRQVQDESQR 1509

Query: 838  NQEA---LAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACL 894
             ++A   LA  ++A+A+A R K    + +    ++A E + +  Q  ++   A+  Q  L
Sbjct: 1510 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER--ARQVQVAL 1567

Query: 895  NT-----DWQIQSLH---KQKCDDLQRN--KCYQEVAKLLRENRRK-----EIEIINAMV 939
             T     + ++QS      +K   L+R+  + +  VA+L  E  R+     E E      
Sbjct: 1568 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627

Query: 940  EEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHK 991
            E E ++W+    +  RLR      A   A +K   + E     E AE    +
Sbjct: 1628 ERELERWQLKANEALRLR----LQAEEVAQQKSLAQAEAEKQKEEAEREARR 1675



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 80/319 (25%), Positives = 136/319 (42%), Gaps = 51/319 (15%)

Query: 691  ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
            E + +R  EL   +  ++RQ  E       QQR+  E     QEL+R   ET    ++  
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1730

Query: 744  LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
            LL+EE   +Q+    A  KR+       KV+ EM +  A++ R  +  +   E   +RL+
Sbjct: 1731 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790

Query: 797  DEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK 856
             E GR      RE+A  A  L     E + Q++L                 A+ DA R++
Sbjct: 1791 AEAGRF-----RELAEEAARLRALAEEAKRQRQL-----------------AEEDAARQR 1828

Query: 857  VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDD--LQRN 914
             + E  +  KL   GE    KT+  I     +AE   L    + ++  +++ ++   Q  
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888

Query: 915  KCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFL 974
               +E    LR+    E+E    +VE+  ++ ++ E +   L    KAS    A+ K  L
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILAL----KASFEKAAAGKAEL 1944

Query: 975  KQEINAAVEHAENPCHKEE 993
            + E+     +AE+    +E
Sbjct: 1945 ELELGRIRSNAEDTLRSKE 1963



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 65/286 (22%), Positives = 124/286 (43%), Gaps = 13/286 (4%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEK 750
            E  RIR++  D LR ++  E   A+  Q   E+E         R+AEE  ++ L  EEE 
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE------RRRREAEERVQKSLAAEEEA 2000

Query: 751  MIQQRQRLAAVKR-ELKVKE-MHLQDAARR---RFLKLQQDQQEMELRRLDDEIGRKVYM 805
              Q++  L  V+R + KV+E   L++ A +   R L+L Q+  +  L+  +      V  
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2060

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFH 865
            +++E+  T +  +    +L  +     +   E +EA  +  R  A + RR+V+  E +  
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQ 2119

Query: 866  KLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLR 925
               E  + ++Q      K      ++A      +  +L +++  D +  K  +   + LR
Sbjct: 2120 SAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179

Query: 926  ENRRKEIEIINAMVE-EEAKKWKEAEGKEFRLRSAKKASALSDASR 970
            +  + E E+    ++ EE    K    +E +   A+   A    S+
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2225



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 72/289 (24%), Positives = 122/289 (42%), Gaps = 31/289 (10%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETR--REMLLQEE 748
            E ER R +      E +  + + A+ +  R    A  + + L  K EE R  RE   QE 
Sbjct: 1978 EEERRRREA-----EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032

Query: 749  EKMIQQRQRLA--AVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMR 806
             + +Q  Q  A   ++ E K     +Q   +     LQQ+Q  ++  R + E  R+    
Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2092

Query: 807  DREIAATA-RDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLE----- 860
              E    A R+    + ++E  +RL  K   E Q     + +A A+  R++ + E     
Sbjct: 2093 AEEARVQAEREAAQSRRQVEEAERL--KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150

Query: 861  --EHMFHKLIEAGETQSQKTQKVIKENL---AKAEQACLNTDWQIQSLHKQK---CDDLQ 912
              E    +  +A + + +K +K  ++ L   A+ EQ       Q++    QK    ++LQ
Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210

Query: 913  RNKCYQEVAKLLRENRRKEIEIINAMVE-EEAKKWK---EAEGKEFRLR 957
            R K   E  +  R+  + E E+ +  V+ EE  K K   EAE +   LR
Sbjct: 2211 RLKA--EATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILR 2257



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 49/215 (22%), Positives = 100/215 (46%), Gaps = 13/215 (6%)

Query: 686  DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
            + QT ++E++  +    +  +L E+ ++   +  ++Q++ + E  +Q +  + KA++ R 
Sbjct: 2475 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2532

Query: 742  EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIG 800
            E   Q+++ M Q+RQRL A   E + ++   ++  RR+  +LQQ +QQ  +   L  E  
Sbjct: 2533 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEEN 2591

Query: 801  RKV-----YMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRR 855
            +++      + ++  AA A   E+   ++ + K L       +  A   E     D  RR
Sbjct: 2592 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRR 2651

Query: 856  KVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
            KV  +      ++ A E Q         + LA+ E
Sbjct: 2652 KVSAQRLQEAGILSAEELQRLAQGHTTVDELARRE 2686



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 78/345 (22%), Positives = 150/345 (43%), Gaps = 44/345 (12%)

Query: 694  RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
            R++ +EL  L+ R   E+    ++ K + QR +++EA   KQ       L   A+E  R 
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293

Query: 743  MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
              L EE+ + QQR   A  ++ LK K   +Q+A R +     L+ Q++  + + RRL ++
Sbjct: 2294 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2349

Query: 799  IGRKVYMRDREIAATARDLE---MRQLELESQKRLYEKNLTENQEALAKEMRADADAYRR 855
              +       E     R LE    RQLE+ ++    +  + E   A A   RA+ DA R 
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA---RAEEDAQRF 2406

Query: 856  KVDLEE--HMFHK----------LIEAGETQSQKTQ---KVIKENLA--KAEQACLNTDW 898
            +   EE     H+          L++  E Q Q++    + ++E +A  + E+  L  + 
Sbjct: 2407 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2466

Query: 899  QIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEII--NAMVEEEAKKWKEAEGKEFRL 956
            ++  L  ++   +Q+ +  QE   L +    ++  ++     +E+E  K ++    E   
Sbjct: 2467 KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAK 2526

Query: 957  RSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
                +        +    +Q + A++E A    H+ E   + +Q+
Sbjct: 2527 AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2571



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 64/289 (22%), Positives = 129/289 (44%), Gaps = 27/289 (9%)

Query: 688  QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
            +  ER R+R  +E+  +R +    + Q   A+ + Q +    +EA  QK++   +AE  R
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500

Query: 741  REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
            R++  + + K   + +  + VK E +      +       L+LQ ++ E  LR+ + E  
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1560

Query: 801  RKVYMRDREIAATAR-DLEMRQLELESQKRLYEKNLTENQEALAK---------EMRADA 850
            R+V +       +A  +L+ ++     +    E++L E   A+A+         + +A+A
Sbjct: 1561 RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEA 1620

Query: 851  DAYRRKVDLE-EHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCD 909
            +  R + + E E    K  EA   + Q  +   +++LA+AE      + + ++  + K  
Sbjct: 1621 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA- 1679

Query: 910  DLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRS 958
                    +E A   RE   +E+E    + E  A++   AE +  RLR+
Sbjct: 1680 --------EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 82/362 (22%), Positives = 148/362 (40%), Gaps = 58/362 (16%)

Query: 705  ERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLA--AVK 762
            ER   E + A  +  R++ EA     E+  K +E   E L +  E    QR+RL   A +
Sbjct: 1832 ERVLAEKLAAIGEATRLKTEA-----EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1886

Query: 763  RELKVKEMHLQ-----DAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATAR-D 816
             +  ++E   Q     D+   R   L +D      R++++EI       ++  A  A  +
Sbjct: 1887 HKADIEERLAQLRKASDSELERQKGLVEDTLRQR-RQVEEEILALKASFEKAAAGKAELE 1945

Query: 817  LEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQ 876
            LE+ ++   ++  L  K   E + A  +++ A+ +  RR+ + EE               
Sbjct: 1946 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE--RRRREAEER-------------- 1989

Query: 877  KTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIIN 936
                 ++++LA  E+A            K   ++++R K   E A+ LRE   +E     
Sbjct: 1990 -----VQKSLAAEEEAARQ--------RKAALEEVERLKAKVEEARRLRERAEQESARQL 2036

Query: 937  AMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKW-----FLKQEINAAVEHAENPCHK 991
             + +E A+K  +AE K       +K   L    ++       L+ E  AA   AE     
Sbjct: 2037 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE---EA 2093

Query: 992  EEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLT 1051
            EE R Q E++++   R  Q+ ++  +  S +     RA       Q   +K+R   ++  
Sbjct: 2094 EEARVQAEREAAQSRR--QVEEAERLKQSAEEQAQARA-----QAQAAAEKLRKEAEQEA 2146

Query: 1052 AR 1053
            AR
Sbjct: 2147 AR 2148


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 83/352 (23%), Positives = 156/352 (44%), Gaps = 45/352 (12%)

Query: 678  NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
            +QY KFI +   +  E  R  E     ER+ + +++A +++QR   EA  Q K +  R+A
Sbjct: 1335 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1394

Query: 737  EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
            +E ++ M   +++ EE  +  +Q+  +++ EL    +  E  +Q      +AA R  L++
Sbjct: 1395 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1454

Query: 784  QQD------QQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTE 837
            +++      Q E   R+     G    +R R   A A+  + ++ E E  +R  +     
Sbjct: 1455 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-EAERLRRQVQDESQR 1513

Query: 838  NQEA---LAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACL 894
             ++A   LA  ++A+A+A R K    + +    ++A E + +  Q  ++   A+  Q  L
Sbjct: 1514 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER--ARQVQVAL 1571

Query: 895  NT-----DWQIQSLH---KQKCDDLQRN--KCYQEVAKLLRENRRK-----EIEIINAMV 939
             T     + ++QS      +K   L+R+  + +  VA+L  E  R+     E E      
Sbjct: 1572 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1631

Query: 940  EEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHK 991
            E E ++W+    +  RLR      A   A +K   + E     E AE    +
Sbjct: 1632 ERELERWQLKANEALRLR----LQAEEVAQQKSLAQAEAEKQKEEAEREARR 1679



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 80/319 (25%), Positives = 136/319 (42%), Gaps = 51/319 (15%)

Query: 691  ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
            E + +R  EL   +  ++RQ  E       QQR+  E     QEL+R   ET    ++  
Sbjct: 1684 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1734

Query: 744  LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
            LL+EE   +Q+    A  KR+       KV+ EM +  A++ R  +  +   E   +RL+
Sbjct: 1735 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1794

Query: 797  DEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRK 856
             E GR      RE+A  A  L     E + Q++L                 A+ DA R++
Sbjct: 1795 AEAGRF-----RELAEEAARLRALAEEAKRQRQL-----------------AEEDAARQR 1832

Query: 857  VDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDD--LQRN 914
             + E  +  KL   GE    KT+  I     +AE   L    + ++  +++ ++   Q  
Sbjct: 1833 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892

Query: 915  KCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFL 974
               +E    LR+    E+E    +VE+  ++ ++ E +   L    KAS    A+ K  L
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILAL----KASFEKAAAGKAEL 1948

Query: 975  KQEINAAVEHAENPCHKEE 993
            + E+     +AE+    +E
Sbjct: 1949 ELELGRIRSNAEDTLRSKE 1967



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 65/286 (22%), Positives = 124/286 (43%), Gaps = 13/286 (4%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEK 750
            E  RIR++  D LR ++  E   A+  Q   E+E         R+AEE  ++ L  EEE 
Sbjct: 1951 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE------RRRREAEERVQKSLAAEEEA 2004

Query: 751  MIQQRQRLAAVKR-ELKVKE-MHLQDAARR---RFLKLQQDQQEMELRRLDDEIGRKVYM 805
              Q++  L  V+R + KV+E   L++ A +   R L+L Q+  +  L+  +      V  
Sbjct: 2005 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2064

Query: 806  RDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFH 865
            +++E+  T +  +    +L  +     +   E +EA  +  R  A + RR+V+  E +  
Sbjct: 2065 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQ 2123

Query: 866  KLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLR 925
               E  + ++Q      K      ++A      +  +L +++  D +  K  +   + LR
Sbjct: 2124 SAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2183

Query: 926  ENRRKEIEIINAMVE-EEAKKWKEAEGKEFRLRSAKKASALSDASR 970
            +  + E E+    ++ EE    K    +E +   A+   A    S+
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2229



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 72/289 (24%), Positives = 122/289 (42%), Gaps = 31/289 (10%)

Query: 691  ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETR--REMLLQEE 748
            E ER R +      E +  + + A+ +  R    A  + + L  K EE R  RE   QE 
Sbjct: 1982 EEERRRREA-----EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2036

Query: 749  EKMIQQRQRLA--AVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMR 806
             + +Q  Q  A   ++ E K     +Q   +     LQQ+Q  ++  R + E  R+    
Sbjct: 2037 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE 2096

Query: 807  DREIAATA-RDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLE----- 860
              E    A R+    + ++E  +RL  K   E Q     + +A A+  R++ + E     
Sbjct: 2097 AEEARVQAEREAAQSRRQVEEAERL--KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154

Query: 861  --EHMFHKLIEAGETQSQKTQKVIKENL---AKAEQACLNTDWQIQSLHKQK---CDDLQ 912
              E    +  +A + + +K +K  ++ L   A+ EQ       Q++    QK    ++LQ
Sbjct: 2155 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2214

Query: 913  RNKCYQEVAKLLRENRRKEIEIINAMVE-EEAKKWK---EAEGKEFRLR 957
            R K   E  +  R+  + E E+ +  V+ EE  K K   EAE +   LR
Sbjct: 2215 RLKA--EATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILR 2261



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 49/215 (22%), Positives = 100/215 (46%), Gaps = 13/215 (6%)

Query: 686  DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
            + QT ++E++  +    +  +L E+ ++   +  ++Q++ + E  +Q +  + KA++ R 
Sbjct: 2479 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2536

Query: 742  EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIG 800
            E   Q+++ M Q+RQRL A   E + ++   ++  RR+  +LQQ +QQ  +   L  E  
Sbjct: 2537 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEEN 2595

Query: 801  RKV-----YMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRR 855
            +++      + ++  AA A   E+   ++ + K L       +  A   E     D  RR
Sbjct: 2596 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRR 2655

Query: 856  KVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAE 890
            KV  +      ++ A E Q         + LA+ E
Sbjct: 2656 KVSAQRLQEAGILSAEELQRLAQGHTTVDELARRE 2690



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 78/345 (22%), Positives = 150/345 (43%), Gaps = 44/345 (12%)

Query: 694  RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
            R++ +EL  L+ R   E+    ++ K + QR +++EA   KQ       L   A+E  R 
Sbjct: 2238 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2297

Query: 743  MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
              L EE+ + QQR   A  ++ LK K   +Q+A R +     L+ Q++  + + RRL ++
Sbjct: 2298 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2353

Query: 799  IGRKVYMRDREIAATARDLE---MRQLELESQKRLYEKNLTENQEALAKEMRADADAYRR 855
              +       E     R LE    RQLE+ ++    +  + E   A A   RA+ DA R 
Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA---RAEEDAQRF 2410

Query: 856  KVDLEE--HMFHK----------LIEAGETQSQKTQ---KVIKENLA--KAEQACLNTDW 898
            +   EE     H+          L++  E Q Q++    + ++E +A  + E+  L  + 
Sbjct: 2411 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2470

Query: 899  QIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEII--NAMVEEEAKKWKEAEGKEFRL 956
            ++  L  ++   +Q+ +  QE   L +    ++  ++     +E+E  K ++    E   
Sbjct: 2471 KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAK 2530

Query: 957  RSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 1001
                +        +    +Q + A++E A    H+ E   + +Q+
Sbjct: 2531 AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2575



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 64/289 (22%), Positives = 129/289 (44%), Gaps = 27/289 (9%)

Query: 688  QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
            +  ER R+R  +E+  +R +    + Q   A+ + Q +    +EA  QK++   +AE  R
Sbjct: 1445 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1504

Query: 741  REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
            R++  + + K   + +  + VK E +      +       L+LQ ++ E  LR+ + E  
Sbjct: 1505 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1564

Query: 801  RKVYMRDREIAATAR-DLEMRQLELESQKRLYEKNLTENQEALAK---------EMRADA 850
            R+V +       +A  +L+ ++     +    E++L E   A+A+         + +A+A
Sbjct: 1565 RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEA 1624

Query: 851  DAYRRKVDLE-EHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCD 909
            +  R + + E E    K  EA   + Q  +   +++LA+AE      + + ++  + K  
Sbjct: 1625 ERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA- 1683

Query: 910  DLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRS 958
                    +E A   RE   +E+E    + E  A++   AE +  RLR+
Sbjct: 1684 --------EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1724



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 82/362 (22%), Positives = 148/362 (40%), Gaps = 58/362 (16%)

Query: 705  ERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLA--AVK 762
            ER   E + A  +  R++ EA     E+  K +E   E L +  E    QR+RL   A +
Sbjct: 1836 ERVLAEKLAAIGEATRLKTEA-----EIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1890

Query: 763  RELKVKEMHLQ-----DAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATAR-D 816
             +  ++E   Q     D+   R   L +D      R++++EI       ++  A  A  +
Sbjct: 1891 HKADIEERLAQLRKASDSELERQKGLVEDTLRQR-RQVEEEILALKASFEKAAAGKAELE 1949

Query: 817  LEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQ 876
            LE+ ++   ++  L  K   E + A  +++ A+ +  RR+ + EE               
Sbjct: 1950 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE--RRRREAEER-------------- 1993

Query: 877  KTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIIN 936
                 ++++LA  E+A            K   ++++R K   E A+ LRE   +E     
Sbjct: 1994 -----VQKSLAAEEEAARQ--------RKAALEEVERLKAKVEEARRLRERAEQESARQL 2040

Query: 937  AMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKW-----FLKQEINAAVEHAENPCHK 991
             + +E A+K  +AE K       +K   L    ++       L+ E  AA   AE     
Sbjct: 2041 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAE---EA 2097

Query: 992  EEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLT 1051
            EE R Q E++++   R  Q+ ++  +  S +     RA       Q   +K+R   ++  
Sbjct: 2098 EEARVQAEREAAQSRR--QVEEAERLKQSAEEQAQARA-----QAQAAAEKLRKEAEQEA 2150

Query: 1052 AR 1053
            AR
Sbjct: 2151 AR 2152


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,284,889
Number of Sequences: 37866
Number of extensions: 1689053
Number of successful extensions: 12233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 868
Number of HSP's that attempted gapping in prelim test: 7055
Number of HSP's gapped (non-prelim): 3268
length of query: 1066
length of database: 18,247,518
effective HSP length: 113
effective length of query: 953
effective length of database: 13,968,660
effective search space: 13312132980
effective search space used: 13312132980
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.