Search of human proteins with 222446616

Search of human proteins with 222446616

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222446616 hypothetical protein LOC341346 [Homo sapiens]
         (343 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222446616 hypothetical protein LOC341346 [Homo sapiens]            681   0.0  
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    46   6e-05
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    46   6e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    45   7e-05
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom...    45   1e-04
gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens]    43   5e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     40   0.003
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       40   0.004
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       40   0.004
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       40   0.004
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    40   0.004
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     39   0.005
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    39   0.005
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    39   0.007
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    38   0.015
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap...    38   0.015
gi|117968353 NUF2, NDC80 kinetochore complex component [Homo sap...    38   0.015
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    37   0.020
gi|55770834 centromere protein F [Homo sapiens]                        37   0.026
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    37   0.026
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    37   0.034
gi|71061468 centromere protein E [Homo sapiens]                        37   0.034
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]          37   0.034
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    36   0.057
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    36   0.057
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 36   0.057
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]          35   0.075
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]          35   0.075
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]          35   0.075
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               35   0.075

>gi|222446616 hypothetical protein LOC341346 [Homo sapiens]
          Length = 343

 Score =  681 bits (1756), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MALTPTNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRS 60
           MALTPTNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRS
Sbjct: 1   MALTPTNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRS 60

Query: 61  DDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLE 120
           DDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLE
Sbjct: 61  DDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLE 120

Query: 121 LCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLK 180
           LCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLK
Sbjct: 121 LCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLK 180

Query: 181 GQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAE 240
           GQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAE
Sbjct: 181 GQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAE 240

Query: 241 DTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTAWKRALRIFIMFDVLTVTGLLCYI 300
           DTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTAWKRALRIFIMFDVLTVTGLLCYI
Sbjct: 241 DTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTAWKRALRIFIMFDVLTVTGLLCYI 300

Query: 301 LFFGATFLFERVLLRMLGCRTTWDLREMREPFLNLEVEALLPS 343
           LFFGATFLFERVLLRMLGCRTTWDLREMREPFLNLEVEALLPS
Sbjct: 301 LFFGATFLFERVLLRMLGCRTTWDLREMREPFLNLEVEALLPS 343


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 62/267 (23%), Positives = 121/267 (45%), Gaps = 22/267 (8%)

Query: 2   ALTPTNLNNKMSLQMKMDCQE-QQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRS 60
           AL   +   +++ Q+ +  Q+ Q+LT        KL + E  +Q+  ++  +++  L   
Sbjct: 239 ALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQ 298

Query: 61  -----DDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSK 115
                 D+D I ++    D  ++ + +  A     LS+Q      +DE  + + SL+ ++
Sbjct: 299 TTKFHQDQDTIMAKLTNEDSQNRQLQQKLAA----LSRQ------IDELEETNRSLRKAE 348

Query: 116 KNLLELCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKD 175
           + L ++  K    K  Y N  I  +V+EL    +D   K + +IK      +  K L ++
Sbjct: 349 EELQDI--KEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERE 406

Query: 176 MLTLKG---QIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKV-IERLEDLCKNVELLSAK 231
            L  K    ++EKL  R + L++       +  E Y LK  +  ER+     + EL S K
Sbjct: 407 TLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLK 466

Query: 232 LRMYQMEAEDTDSHSSEEIDTEEMEAL 258
           +R+ ++EA ++    +E    E++  L
Sbjct: 467 VRIKELEAIESRLEKTEFTLKEDLTKL 493



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 31/216 (14%)

Query: 34  QKLNVTEGAMQ----DLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEHDQ 89
           +KL  TE  +Q     L  E  KV  + ++  +E   + ++ +TD   K M  +  E D 
Sbjct: 509 EKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKS-KTDVEEK-MYSVTKERD- 565

Query: 90  DLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGADYI 149
           DL  + K E +   D  +  ++  ++   LE   K  FLK N  N   G     L  +  
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKD-FLK-NKLNQDSGKSTTALHQE-- 621

Query: 150 DGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYE 209
                 +N IK+++     +K  LKDM  ++  + K ED           E  T    Y 
Sbjct: 622 ------NNKIKELSQEVERLKLKLKDMKAIEDDLMKTED-----------EYETLERRYA 664

Query: 210 LKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSH 245
            ++   ++ + L K +E +  +L  Y++  +   SH
Sbjct: 665 NER---DKAQFLSKELEHVKMELAKYKLAEKTETSH 697


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 62/267 (23%), Positives = 121/267 (45%), Gaps = 22/267 (8%)

Query: 2   ALTPTNLNNKMSLQMKMDCQE-QQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRS 60
           AL   +   +++ Q+ +  Q+ Q+LT        KL + E  +Q+  ++  +++  L   
Sbjct: 239 ALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQ 298

Query: 61  -----DDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSK 115
                 D+D I ++    D  ++ + +  A     LS+Q      +DE  + + SL+ ++
Sbjct: 299 TTKFHQDQDTIMAKLTNEDSQNRQLQQKLAA----LSRQ------IDELEETNRSLRKAE 348

Query: 116 KNLLELCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKD 175
           + L ++  K    K  Y N  I  +V+EL    +D   K + +IK      +  K L ++
Sbjct: 349 EELQDI--KEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERE 406

Query: 176 MLTLKG---QIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKV-IERLEDLCKNVELLSAK 231
            L  K    ++EKL  R + L++       +  E Y LK  +  ER+     + EL S K
Sbjct: 407 TLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLK 466

Query: 232 LRMYQMEAEDTDSHSSEEIDTEEMEAL 258
           +R+ ++EA ++    +E    E++  L
Sbjct: 467 VRIKELEAIESRLEKTEFTLKEDLTKL 493



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 31/216 (14%)

Query: 34  QKLNVTEGAMQ----DLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEHDQ 89
           +KL  TE  +Q     L  E  KV  + ++  +E   + ++ +TD   K M  +  E D 
Sbjct: 509 EKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKS-KTDVEEK-MYSVTKERD- 565

Query: 90  DLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGADYI 149
           DL  + K E +   D  +  ++  ++   LE   K  FLK N  N   G     L  +  
Sbjct: 566 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKD-FLK-NKLNQDSGKSTTALHQE-- 621

Query: 150 DGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYE 209
                 +N IK+++     +K  LKDM  ++  + K ED           E  T    Y 
Sbjct: 622 ------NNKIKELSQEVERLKLKLKDMKAIEDDLMKTED-----------EYETLERRYA 664

Query: 210 LKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSH 245
            ++   ++ + L K +E +  +L  Y++  +   SH
Sbjct: 665 NER---DKAQFLSKELEHVKMELAKYKLAEKTETSH 697


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 49/225 (21%), Positives = 101/225 (44%), Gaps = 22/225 (9%)

Query: 23  QQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLE 82
           +QL+++     Q     EG    L++EI K+         ++DI+S   +  +      +
Sbjct: 351 KQLSQEKGRLHQLYETKEGETTRLIREIDKL---------KEDINSHVIKVKWAQN---K 398

Query: 83  LEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKN---LLELCLKGMFLKLNYWNTKIGL 139
           L+AE D     +DK +    +  QA       +KN   +++   +   +K N  + K+ +
Sbjct: 399 LKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRV 458

Query: 140 QVKELGADYIDGTEKIDNI---IKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQG 196
              EL     + +++++     IK++   + T K  + ++ TL+ +++ LED  L     
Sbjct: 459 TKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERL----R 514

Query: 197 TSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAED 241
           T  E++   E+   +K  I+ L D  K  + L  +L+  + E E+
Sbjct: 515 TEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIEN 559



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 8/198 (4%)

Query: 35  KLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEA-EHDQDLSK 93
           K N TE  +  +L E+         S +E   S     TD   K + ++++    +DL +
Sbjct: 107 KTNETEQKVTQILVELRS--STFPESANEKTYSESPYDTDCTKKFISKIKSVSASEDLLE 164

Query: 94  QDKQETDVDEDPQASTSLQFSKKN----LLELCLKGMFLKLNYWNTKIGLQVKELGADYI 149
           + + E    E  +       +K      L E C++  +L+  +   K+  + K+    ++
Sbjct: 165 EIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFV 224

Query: 150 DGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKL-EDRGLDLDQGTSTEVNTCNEVY 208
           D   + DN+ +++     T K  +  +  L+ +IE+L ++     DQ  + +V   N V 
Sbjct: 225 DICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQ 284

Query: 209 ELKKKVIERLEDLCKNVE 226
           +L K++ +R+E   K  E
Sbjct: 285 QLHKEMAQRMEQANKKCE 302


>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
           sapiens]
          Length = 893

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 60/258 (23%), Positives = 118/258 (45%), Gaps = 22/258 (8%)

Query: 11  KMSLQMKMDCQE-QQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRS-----DDED 64
           +++ Q+ +  Q+ Q+LT        KL + E  +Q+  ++  +++  L         D+D
Sbjct: 8   RLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQD 67

Query: 65  DISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLK 124
            I ++    D  ++ + +  A     LS+Q      +DE  + + SL+ +++ L ++  K
Sbjct: 68  TIMAKLTNEDSQNRQLQQKLAA----LSRQ------IDELEETNRSLRKAEEELQDI--K 115

Query: 125 GMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKG--- 181
               K  Y N  I  +V+EL    +D   K + +IK      +  K L ++ L  K    
Sbjct: 116 EKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKL 175

Query: 182 QIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKV-IERLEDLCKNVELLSAKLRMYQMEAE 240
           ++EKL  R + L++       +  E Y LK  +  ER+     + EL S K+R+ ++EA 
Sbjct: 176 EVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAI 235

Query: 241 DTDSHSSEEIDTEEMEAL 258
           ++    +E    E++  L
Sbjct: 236 ESRLEKTEFTLKEDLTKL 253



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 31/216 (14%)

Query: 34  QKLNVTEGAMQ----DLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEHDQ 89
           +KL  TE  +Q     L  E  KV  + ++  +E   + ++ +TD   K M  +  E D 
Sbjct: 269 EKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKS-KTDVEEK-MYSVTKERD- 325

Query: 90  DLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGADYI 149
           DL  + K E +   D  +  ++  ++   LE   K  FLK N  N   G     L  +  
Sbjct: 326 DLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKD-FLK-NKLNQDSGKSTTALHQE-- 381

Query: 150 DGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYE 209
                 +N IK+++     +K  LKDM  ++  + K ED           E  T    Y 
Sbjct: 382 ------NNKIKELSQEVERLKLKLKDMKAIEDDLMKTED-----------EYETLERRYA 424

Query: 210 LKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSH 245
            ++   ++ + L K +E +  +L  Y++  +   SH
Sbjct: 425 NER---DKAQFLSKELEHVKMELAKYKLAEKTETSH 457


>gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens]
          Length = 288

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 83/339 (24%), Positives = 126/339 (37%), Gaps = 69/339 (20%)

Query: 10  NKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSE 69
           N +SL M ++   Q++ + N     K+   E  +Q L  EII+   +++    +++   E
Sbjct: 12  NIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE----DEEWEKE 67

Query: 70  NPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLK 129
           N  T    + + ELE E  +   K       + E  Q  T       N  +    G   +
Sbjct: 68  NRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEE 127

Query: 130 LNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDR 189
                TK+ LQ  +L A Y                     K LLK M       +  ED+
Sbjct: 128 -----TKVKLQ--QLEASYACQE-----------------KELLKVMKEYAFVTQLCEDQ 163

Query: 190 GLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSEE 249
            L +            +  E  KK+ E LE L    E+ S  + M  +E E T  ++   
Sbjct: 164 ALYI-----------KKYQETLKKIEEELEALFLEREV-SKLVSMNPVEKEHTSQNN--- 208

Query: 250 IDTEEMEALLPQAPASFLVQKSPPRNTAWKRALRIF--IMFDVLTVTGLLCYILFFGATF 307
                              + +P + TA   + +IF  + F  L    LL Y +FF   F
Sbjct: 209 -------------------EGTPTQKTARLFSKKIFCCLFFITLFFIRLLSY-MFFHVRF 248

Query: 308 ----LFERVLLRMLGCRTTWDLREMREPFLNLEVEALLP 342
               L   VL ++LG  T W LR    P L LE E +LP
Sbjct: 249 INPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLP 287


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 44/241 (18%), Positives = 115/241 (47%), Gaps = 20/241 (8%)

Query: 17   KMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKV-DHILDRSDDEDDIS----SENP 71
            + DC + ++    +   +K +  E  ++     I+++ DHI  ++ + + ++    + N 
Sbjct: 1494 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ 1553

Query: 72   QTDFLHKGMLELEAEHDQDLSKQ-DKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKL 130
            Q D  HK +++ + +H Q+L ++ D +  + +E      +  +S K  LE   K    +L
Sbjct: 1554 QKDIEHKELVQ-KLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK----EL 1608

Query: 131  NYWNTKIGLQVKELGA--DYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLED 188
             + N  +  + +EL A  D ++ +E    + +     E  + ++ K +L+      ++E+
Sbjct: 1609 EHVNLSVKSKEEELKALEDRLE-SESAAKLAELKRKAEQKIAAIKKQLLS------QMEE 1661

Query: 189  RGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSE 248
            +     +GT + ++  N   + +++ +  LE+  K+VE   ++  +    A++  +++ +
Sbjct: 1662 KEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ 1721

Query: 249  E 249
            E
Sbjct: 1722 E 1722



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 56/237 (23%), Positives = 105/237 (44%), Gaps = 30/237 (12%)

Query: 28   KNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLE-LEAE 86
            ++N    KL   E   Q L KEI+++   L     E             H+  LE L+ E
Sbjct: 1924 QHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE-------------HQQELEILKKE 1970

Query: 87   HDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGA 146
            +DQ+  ++ KQE +  E    ST  Q  ++   +L  K   L++    T    + +E+ A
Sbjct: 1971 YDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETI--NKAQEVEA 2028

Query: 147  DYIDG-TEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCN 205
            + ++   E+ + ++KKI   ++ +K       T K   E L+ R    ++ T+   +   
Sbjct: 2029 ELLESHQEETNQLLKKIAEKDDDLKR------TAKRYEEILDARE---EEMTAKVRDLQT 2079

Query: 206  EVYELKKKVIERLEDL----CKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEAL 258
            ++ EL+KK  ++LE        NV ++  + ++ Q     +DS   E+   E++  L
Sbjct: 2080 QLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNL 2136


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 62/300 (20%), Positives = 119/300 (39%), Gaps = 38/300 (12%)

Query: 2   ALTPTNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSD 61
           ++T  N N + S+++     E+ +TKK   + Q+LN  +     L  ++ K  H  +R +
Sbjct: 469 SITEINANFEKSVRLN----EEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLE 524

Query: 62  DEDD------ISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDE--DPQASTSLQF 113
            E +       ++ N   + L +  LEL      D+S+ +   +++ +  D     + Q 
Sbjct: 525 AEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQV 584

Query: 114 SKKNLLELCLKGMFLK---------LNYWNTKIGL-----QVKELGADYIDGTEKIDNII 159
            K  +    LKG   +         L   + ++ L     ++KE+   + +G  K    I
Sbjct: 585 HKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSI 644

Query: 160 KKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVI--ER 217
            K N +E  ++    + L L+ Q+E     G          +N   +  E  K+ +  ER
Sbjct: 645 GKQNSSEERIRQRELENLLLERQLEDARKEG----DNKEIVINIHRDCLENGKEDLLEER 700

Query: 218 LEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTA 277
            ++L      L  KL  Y+ E       +  E+   E +  L      F + +SP   T+
Sbjct: 701 NKELMNEYNYLKEKLLQYEKE------KAEREVIVREFQEELVDHLKKFSMSESPLEGTS 754


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 62/300 (20%), Positives = 119/300 (39%), Gaps = 38/300 (12%)

Query: 2   ALTPTNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSD 61
           ++T  N N + S+++     E+ +TKK   + Q+LN  +     L  ++ K  H  +R +
Sbjct: 498 SITEINANFEKSVRLN----EEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLE 553

Query: 62  DEDD------ISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDE--DPQASTSLQF 113
            E +       ++ N   + L +  LEL      D+S+ +   +++ +  D     + Q 
Sbjct: 554 AEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQV 613

Query: 114 SKKNLLELCLKGMFLK---------LNYWNTKIGL-----QVKELGADYIDGTEKIDNII 159
            K  +    LKG   +         L   + ++ L     ++KE+   + +G  K    I
Sbjct: 614 HKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSI 673

Query: 160 KKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVI--ER 217
            K N +E  ++    + L L+ Q+E     G          +N   +  E  K+ +  ER
Sbjct: 674 GKQNSSEERIRQRELENLLLERQLEDARKEG----DNKEIVINIHRDCLENGKEDLLEER 729

Query: 218 LEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTA 277
            ++L      L  KL  Y+ E       +  E+   E +  L      F + +SP   T+
Sbjct: 730 NKELMNEYNYLKEKLLQYEKE------KAEREVIVREFQEELVDHLKKFSMSESPLEGTS 783


>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1139

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 62/300 (20%), Positives = 119/300 (39%), Gaps = 38/300 (12%)

Query: 2   ALTPTNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSD 61
           ++T  N N + S+++     E+ +TKK   + Q+LN  +     L  ++ K  H  +R +
Sbjct: 498 SITEINANFEKSVRLN----EEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLE 553

Query: 62  DEDD------ISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDE--DPQASTSLQF 113
            E +       ++ N   + L +  LEL      D+S+ +   +++ +  D     + Q 
Sbjct: 554 AEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQV 613

Query: 114 SKKNLLELCLKGMFLK---------LNYWNTKIGL-----QVKELGADYIDGTEKIDNII 159
            K  +    LKG   +         L   + ++ L     ++KE+   + +G  K    I
Sbjct: 614 HKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSI 673

Query: 160 KKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVI--ER 217
            K N +E  ++    + L L+ Q+E     G          +N   +  E  K+ +  ER
Sbjct: 674 GKQNSSEERIRQRELENLLLERQLEDARKEG----DNKEIVINIHRDCLENGKEDLLEER 729

Query: 218 LEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTA 277
            ++L      L  KL  Y+ E       +  E+   E +  L      F + +SP   T+
Sbjct: 730 NKELMNEYNYLKEKLLQYEKE------KAEREVIVREFQEELVDHLKKFSMSESPLEGTS 783


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 57/249 (22%), Positives = 104/249 (41%), Gaps = 34/249 (13%)

Query: 17   KMDCQEQQL-TKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDE------DDISSE 69
            K+D Q Q+L  K + G   ++ + E A + L  E+  V  +L+ ++ +      D  S E
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVELAEKASK-LQNELDNVSTLLEEAEKKGIKFAKDAASLE 1314

Query: 70   NPQTDFLHKGMLELEAEHDQDLSKQDKQ-ETDVDEDPQASTSLQFSKKNLLELCLKGMFL 128
            +   D   + +L+ E     +LS + +Q E + +   +     + ++KNL +        
Sbjct: 1315 SQLQDT--QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK-------- 1364

Query: 129  KLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLED 188
                       QV  L +   D  +K+D+ +  I   E   K LLKD   L    ++LE+
Sbjct: 1365 -----------QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALS---QRLEE 1410

Query: 189  RGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSE 248
            + L  D+   T+     E+ +L    ++    +  N+E    K      E +   +  +E
Sbjct: 1411 KALAYDKLEKTKNRLQQELDDLTVD-LDHQRQVASNLEKKQKKFDQLLAEEKSISARYAE 1469

Query: 249  EIDTEEMEA 257
            E D  E EA
Sbjct: 1470 ERDRAEAEA 1478



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 58/262 (22%), Positives = 110/262 (41%), Gaps = 29/262 (11%)

Query: 11   KMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEI-IKVDHILDRSDDEDDISSE 69
            K  L    +   Q+L +K   +  KL  T+  +Q  L ++ + +DH   +     ++  +
Sbjct: 1394 KKKLLKDAEALSQRLEEKALAY-DKLEKTKNRLQQELDDLTVDLDH---QRQVASNLEKK 1449

Query: 70   NPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLK 129
              + D L      + A + ++   +D+ E +  E    + SL  + +  LE   K  F +
Sbjct: 1450 QKKFDQLLAEEKSISARYAEE---RDRAEAEAREKETKALSLARALEEALEA--KEEFER 1504

Query: 130  LNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDR 189
             N          K+L AD  D     D++ K ++  E + ++L + +  ++ Q+E+LED 
Sbjct: 1505 QN----------KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDE 1554

Query: 190  -GLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAED------- 241
                 D     EVN      + ++ +  R E   +   LL  ++R  + E ED       
Sbjct: 1555 LQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRAL 1614

Query: 242  -TDSHSSEEIDTEEMEALLPQA 262
               S    EID +++EA +  A
Sbjct: 1615 AVASKKKMEIDLKDLEAQIEAA 1636



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 48/277 (17%), Positives = 117/277 (42%), Gaps = 42/277 (15%)

Query: 11   KMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSEN 70
            + + Q++ D ++   +K + G  + ++  E + + L +++ ++   L+  +DE   + + 
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVG--KNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDA 1561

Query: 71   PQTDFLHKGMLELEAEHDQDLSKQDKQETDVD--------------EDPQASTSLQFSKK 116
                 L   M  ++A+ ++DL  +D+Q  +                ED +   +L  + K
Sbjct: 1562 KLR--LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619

Query: 117  NLLELCLKGMFLKLNYWNT----------KIGLQVKELGADYIDGTEKIDNIIKKINVTE 166
              +E+ LK +  ++   N           K+  Q+K+   +  +     D I  +   +E
Sbjct: 1620 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679

Query: 167  NTVKSLLKDMLTLKGQI--------------EKLEDRGLDLDQGTSTEVNTCNEVYELKK 212
              +KSL  ++L L+ ++              ++L D   +   G S  ++    +     
Sbjct: 1680 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIA 1739

Query: 213  KVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSEE 249
            ++ E LE+   N+ELL+ + R   ++ +  ++  + E
Sbjct: 1740 QLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAE 1776



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 68/289 (23%), Positives = 115/289 (39%), Gaps = 50/289 (17%)

Query: 17   KMDCQEQQLTKKNNGFFQKLNV-------TEGAMQDLLKEIIKVDHILDRSDDEDDISSE 69
            +M+ + QQL ++ N   ++L          E     L  +  +++ IL   D E  +  E
Sbjct: 877  EMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILH--DLESRVEEE 934

Query: 70   NPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGM--- 126
              +   L     +++A H QDL +Q      +DE+  A   LQ  K    E  +K M   
Sbjct: 935  EERNQILQNEKKKMQA-HIQDLEEQ------LDEEEGARQKLQLEKVTA-EAKIKKMEEE 986

Query: 127  FLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKL 186
             L L   N+K  ++ K+L  D      +I     ++   E   K+L K     +  I  L
Sbjct: 987  ILLLEDQNSKF-IKEKKLMED------RIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL 1039

Query: 187  EDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSA-----KLRMYQMEAE- 240
            E+R          E  T  E+ + K+K+     DL   +  L A     KL++ + E E 
Sbjct: 1040 EER-------LKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092

Query: 241  --------DTDSHSSEEID-TEEMEALLPQAPASFLVQKSPPRNTAWKR 280
                    D   H +  +    E++A + +    F  +K+  RN A K+
Sbjct: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKA-SRNKAEKQ 1140


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 46/217 (21%), Positives = 93/217 (42%), Gaps = 31/217 (14%)

Query: 35  KLNVTEGAMQDLLKEI--IKVDHILDRSDDEDDISS---ENPQTDFLHKGMLELEAE--- 86
           K+   E  ++DL  EI  +K + +L+  D E++I         + F+   + +L+ E   
Sbjct: 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSK 445

Query: 87  -HDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKE-- 143
              + L+ Q K ET  +++      ++  K++L     +   L+      ++ L+ KE  
Sbjct: 446 KESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESF 505

Query: 144 -----------------LGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKL 186
                            L  +  D  + ++   +KINV +  +++L + +     Q+  L
Sbjct: 506 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNL 565

Query: 187 EDRGLDL---DQGTSTEVNTCNEVYELKKKVIERLED 220
           +DR   L      T T + T  E    K+++IERL++
Sbjct: 566 KDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKE 602


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 43/253 (16%), Positives = 100/253 (39%), Gaps = 26/253 (10%)

Query: 11   KMSLQMKMDC---QEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDIS 67
            K  +Q K+       ++  K+N    ++L++  G ++ L K +         +D E  +S
Sbjct: 1478 KQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSL---------ADVESQVS 1528

Query: 68   SENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNL--------- 118
            ++N + D +   +  L+ E D+ +++ D+   +      +  SL+ + + L         
Sbjct: 1529 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVK 1588

Query: 119  -LELCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDML 177
             +E        +   W  K     KEL  +Y    +  +N+  +    ++ V+++ ++  
Sbjct: 1589 EIESLKSSKIAESTEWQEKH----KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQ 1644

Query: 178  TLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQM 237
             L G++   E    + ++          E+ E  +K  +  +     +E  + +LR    
Sbjct: 1645 ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVH 1704

Query: 238  EAEDTDSHSSEEI 250
             A DT     E +
Sbjct: 1705 PAGDTAKECMETL 1717



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 56/271 (20%), Positives = 123/271 (45%), Gaps = 34/271 (12%)

Query: 12   MSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENP 71
            +S+ ++ D   Q+   +NN   +++      M DL  E  K+D  L +    +D++    
Sbjct: 2488 LSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQY--REDLNQVIT 2545

Query: 72   QTDFLHKGMLELEAEHDQDL-SKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKL 130
              D   K +LE++ + +++L +K  K E  + E  +A+  L+ S  N L+   + +  ++
Sbjct: 2546 IKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRS-FNALQEEKQDLSKEI 2604

Query: 131  NYWNTKIGLQVKELGADYIDGT------------EKIDNIIKKINVTENTVKSLLKDMLT 178
                  I    +++ A   +GT            E++  +    + ++  +  L ++++ 
Sbjct: 2605 ESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVC 2664

Query: 179  LK-------GQIE---KLEDRGLDLDQG-TSTEVNTCNE-VYELKKKVIE---RLEDLCK 223
            ++       G+IE   K E + L  D G    E  T  E V EL + ++E   +L  + K
Sbjct: 2665 VQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2724

Query: 224  NVELLSAKLRMY---QMEAEDTDSHSSEEID 251
              + L+A+++ +       +++  H++EE+D
Sbjct: 2725 ENKGLTAQIQSFGRSMSSLQNSRDHANEELD 2755


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 60/255 (23%), Positives = 110/255 (43%), Gaps = 54/255 (21%)

Query: 27   KKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSD-----DEDDISSENPQTDFLHKGML 81
            + N    ++L + E     LL+E+ ++   L++++      E ++   + +   LH    
Sbjct: 1666 RSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNT 1725

Query: 82   ELEAEHDQDLSKQDKQETDVDE-DPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQ 140
             L       ++ + K E D+ +   +   S+Q S+ N  E   K +        T   + 
Sbjct: 1726 SL-------INTKKKLEADIAQCQAEVENSIQESR-NAEEKAKKAI--------TDAAMM 1769

Query: 141  VKELGADYIDGTEKIDNIIKKINVTENTVKSLLK-----DMLTLKG---QIEKLEDR--- 189
             +EL  +  D +  ++ + K +   E TVK L       + L LKG   QI+KLE+R   
Sbjct: 1770 AEELKKEQ-DTSAHLERMKKNL---EQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRE 1825

Query: 190  ---GLDLDQGTSTEVNTCNEVYELK-----------KKVIERLEDLCKNVELLSAKLRMY 235
                LD++Q    E       YE K            K I RL+DL   V+ L AK++ Y
Sbjct: 1826 LENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDL---VDKLQAKVKSY 1882

Query: 236  QMEAEDTDSHSSEEI 250
            + +AE+ +  ++ ++
Sbjct: 1883 KRQAEEAEEQANTQL 1897


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
           sapiens]
          Length = 725

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 67/300 (22%), Positives = 120/300 (40%), Gaps = 66/300 (22%)

Query: 5   PTNLNNKMSLQMKMDCQEQQ-----LTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDR 59
           P +     S + K + Q+       L K+     Q+    +  +QDL  E+ K++  L+ 
Sbjct: 63  PASARKVKSSESKKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNA 122

Query: 60  SDDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLL 119
           +  E    S N  T  L K ++EL               T  +E  ++  S   ++KNL 
Sbjct: 123 ALREKTSLSANNAT--LEKQLIEL---------------TRTNELLKSKFSENGNQKNLR 165

Query: 120 ELCLKGMFLKLNYWNTKI-GLQVKELGADYIDGTEKIDNIIKKINVTENTVK-------- 170
            L L+ M L+ N   TK+ G+  K+ G +             K+ VT+ +++        
Sbjct: 166 ILSLELMKLR-NKRETKMRGMMAKQEGMEM------------KLQVTQRSLEESQGKIAQ 212

Query: 171 ------SLLKDMLTLKGQIEKL--------------EDRGLDLDQGTSTEVNTCNEVYEL 210
                 S+ K+ +  K + EKL              E   LD+ Q         +E+  L
Sbjct: 213 LEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSL 272

Query: 211 KKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQK 270
           K+ + E +  L K VE L+ K ++ + E ED  + + E    E + A +      F++++
Sbjct: 273 KQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREH--NENLNAEMQNLKQKFILEQ 330



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 12/214 (5%)

Query: 22  EQQLTKKNNGFFQKLNVTEGAMQDLLKEI--IKVDHILDRSDDEDDISSENPQTDFLHKG 79
           E+ L +KN+         E  +  L K++  + V   L   + ED ++      + L+  
Sbjct: 259 EENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE 318

Query: 80  MLELEAE---HDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTK 136
           M  L+ +     Q+  K  ++E  +D   Q    L  S    L    + M  + N +  +
Sbjct: 319 MQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEE 378

Query: 137 IGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQG 196
           +   + EL        E+ + ++K++   E   KS  +++  L+   EKL+ +  +L++ 
Sbjct: 379 LKQTLDELDK-LQQKEEQAERLVKQL---EEEAKSRAEELKLLE---EKLKGKEAELEKS 431

Query: 197 TSTEVNTCNEVYELKKKVIERLEDLCKNVELLSA 230
           ++        + E    +++ LED+    E   A
Sbjct: 432 SAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKA 465


>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 10/106 (9%)

Query: 150 DGTEKIDNIIKKINVTENTVKSLL----KDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCN 205
           D  E  ++ +KK+   EN+ K L+    + + T + +I K  +   D+ Q   T +  CN
Sbjct: 322 DQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHE---DVKQYKRTVIEDCN 378

Query: 206 EVYELKKKVIERLEDLCKNVELLSAKLRMYQM-EAEDTDSHSSEEI 250
           +V E +  V ER+  +  N E+   KL + Q+ +A + +   S+EI
Sbjct: 379 KVQEKRGAVYERVTTI--NQEIQKIKLGIQQLKDAAEREKLKSQEI 422


>gi|117968353 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 10/106 (9%)

Query: 150 DGTEKIDNIIKKINVTENTVKSLL----KDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCN 205
           D  E  ++ +KK+   EN+ K L+    + + T + +I K  +   D+ Q   T +  CN
Sbjct: 322 DQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHE---DVKQYKRTVIEDCN 378

Query: 206 EVYELKKKVIERLEDLCKNVELLSAKLRMYQM-EAEDTDSHSSEEI 250
           +V E +  V ER+  +  N E+   KL + Q+ +A + +   S+EI
Sbjct: 379 KVQEKRGAVYERVTTI--NQEIQKIKLGIQQLKDAAEREKLKSQEI 422


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
           sapiens]
          Length = 724

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 65/283 (22%), Positives = 115/283 (40%), Gaps = 61/283 (21%)

Query: 17  KMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFL 76
           K D   + L K+     Q+    +  +QDL  E+ K++  L+ +  E    S N  T  L
Sbjct: 79  KNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNAT--L 136

Query: 77  HKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTK 136
            K ++EL               T  +E  ++  S   ++KNL  L L+ M L+ N   TK
Sbjct: 137 EKQLIEL---------------TRTNELLKSKFSENGNQKNLRILSLELMKLR-NKRETK 180

Query: 137 I-GLQVKELGADYIDGTEKIDNIIKKINVTENTVK--------------SLLKDMLTLKG 181
           + G+  K+ G +             K+ VT+ +++              S+ K+ +  K 
Sbjct: 181 MRGMMAKQEGMEM------------KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKS 228

Query: 182 QIEKL--------------EDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVEL 227
           + EKL              E   LD+ Q         +E+  LK+ + E +  L K VE 
Sbjct: 229 ETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVED 288

Query: 228 LSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQK 270
           L+ K ++ + E ED  + + E    E + A +      F++++
Sbjct: 289 LNVKCQLLEKEKEDHVNRNREH--NENLNAEMQNLKQKFILEQ 329



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 12/214 (5%)

Query: 22  EQQLTKKNNGFFQKLNVTEGAMQDLLKEI--IKVDHILDRSDDEDDISSENPQTDFLHKG 79
           E+ L +KN+         E  +  L K++  + V   L   + ED ++      + L+  
Sbjct: 258 EENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE 317

Query: 80  MLELEAE---HDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTK 136
           M  L+ +     Q+  K  ++E  +D   Q    L  S    L    + M  + N +  +
Sbjct: 318 MQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEE 377

Query: 137 IGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQG 196
           +   + EL        E+ + ++K++   E   KS  +++  L+   EKL+ +  +L++ 
Sbjct: 378 LKQTLDELDK-LQQKEEQAERLVKQL---EEEAKSRAEELKLLE---EKLKGKEAELEKS 430

Query: 197 TSTEVNTCNEVYELKKKVIERLEDLCKNVELLSA 230
           ++        + E    +++ LED+    E   A
Sbjct: 431 SAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKA 464


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 37.0 bits (84), Expect = 0.026
 Identities = 63/298 (21%), Positives = 122/298 (40%), Gaps = 48/298 (16%)

Query: 1   MALTPTNLNNKMS-LQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDR 59
           M L  + L  ++  L+ K+     ++  K+   +Q L+    +++DLLK     D  L  
Sbjct: 721 MCLKTSQLTGQVEDLEHKLQLLSNEIMDKDR-CYQDLHAEYESLRDLLKS---KDASLVT 776

Query: 60  SDDEDDISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLL 119
           ++D         Q   +H     +  E     S++ +   + D+ P+ S  LQ ++ + L
Sbjct: 777 NEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQ-NRVDSL 835

Query: 120 ELCLKGMFLKLNYWNTKIGLQVKEL------------------GADYIDGTEKIDNIIKK 161
           E  L+         N+ +  Q +EL                   +   + +++I  + + 
Sbjct: 836 EFSLESQ----KQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQED 891

Query: 162 INVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDL 221
            +  +N V   L  +   + +++ L D+ ++ +Q          E+ ELKK     LED 
Sbjct: 892 TSAHQNVVAETLSALENKEKELQLLNDK-VETEQA---------EIQELKKSN-HLLEDS 940

Query: 222 CKNVELLSAKLRMYQMEAEDTDSHSSEEID--------TEEMEALLPQAPASFLVQKS 271
            K ++LLS  L + + E     S +  EI+         +E+ A L Q   + L+QKS
Sbjct: 941 LKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN-LIQKS 997



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 28/134 (20%), Positives = 57/134 (42%), Gaps = 16/134 (11%)

Query: 72  QTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLN 131
           Q D L K   + + + D   +   KQ+  V+ +    T+L+   + L+E+C     L+  
Sbjct: 26  QLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICES---LEKT 82

Query: 132 YWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGL 191
                  LQVKE   ++ +G         ++N  +  ++ L +++   K ++E+ +    
Sbjct: 83  KQKISHELQVKESQVNFQEG---------QLNSGKKQIEKLEQELKRCKSELERSQQAA- 132

Query: 192 DLDQGTSTEVNTCN 205
              Q     +N CN
Sbjct: 133 ---QSADVSLNPCN 143


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 37.0 bits (84), Expect = 0.026
 Identities = 51/214 (23%), Positives = 99/214 (46%), Gaps = 26/214 (12%)

Query: 34   QKLNVTEGAM--QDLLKE---IIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEHD 88
            QK+  +  A   QD+L++   I+K++  L    +    S +N  T  L+   L+L+ E  
Sbjct: 1133 QKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKN--TKDLNVKELKLKEEIT 1190

Query: 89   QDLSK-QDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGAD 147
            Q  +  QD +     ++ +  T+ Q ++K   EL       +    N K  LQ KE   D
Sbjct: 1191 QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ----NLKADLQRKE--ED 1244

Query: 148  YIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEV 207
            Y D  EK+ +  K+I   +  V  +  +   L+ +I +LE +            N C++ 
Sbjct: 1245 YADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKK-----------KNQCSQE 1293

Query: 208  YELKKKVIERLEDLCKNVELLSAKLRMYQMEAED 241
             ++K++ I++L++   N ++  A ++ Y+   +D
Sbjct: 1294 LDMKQRTIQQLKEQLNNQKVEEA-IQQYERACKD 1326



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 56/249 (22%), Positives = 105/249 (42%), Gaps = 37/249 (14%)

Query: 21   QEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDI--SSENPQTDFLHK 78
            ++ +L K+   F Q+L+++E     L KE+ ++    D +  E  +  S    Q + + K
Sbjct: 864  EKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMK 923

Query: 79   GMLELEAEH---DQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELC-LKGMFLKLNYWN 134
               E+E        ++S+     T +DE     +  Q S  +LL L  L     + N  N
Sbjct: 924  LSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPN 983

Query: 135  TKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLD 194
            T++ L    LG DY+   +  +  I++ N  EN+  S           IE + +      
Sbjct: 984  TQLDL----LGNDYLVSKQVKEYRIQEPN-RENSFHS----------SIEAIWEE----- 1023

Query: 195  QGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAE--DTDSHSSEEIDT 252
                     C E+ +   K   ++E+L + +E L A+++ Y+ E        H +++   
Sbjct: 1024 ---------CKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLL 1074

Query: 253  EEMEALLPQ 261
            +E E L+ Q
Sbjct: 1075 KEKETLIQQ 1083



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 16/144 (11%)

Query: 150 DGTEKIDNIIKKINVTENTVKSLLKDM-----LTLKGQIEKLEDRGLDLDQGTSTEVNTC 204
           +   KI N+ +     EN+++ L++D      L    + + +E + LD D   + E N  
Sbjct: 507 NSNSKILNVKRATISWENSLEDLMEDEDLVEELENAEETQNVETKLLDEDLDKTLEENKA 566

Query: 205 NEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPA 264
              +E K+K+++ +EDL K  +L++ K     +E +       EE+ T+E      Q  A
Sbjct: 567 FISHEEKRKLLDLIEDLKK--KLINEKKEKLTLEFK-----IREEV-TQEFTQYWAQREA 618

Query: 265 SF---LVQKSPPRNTAWKRALRIF 285
            F   L+Q+        +R L IF
Sbjct: 619 DFKETLLQEREILEENAERRLAIF 642


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 36/174 (20%), Positives = 80/174 (45%), Gaps = 14/174 (8%)

Query: 82   ELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKI-GLQ 140
            ELEAE  Q   K  +  T V+E  +    LQ  KK L +   +   +K +   T +  ++
Sbjct: 1102 ELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNME 1161

Query: 141  V-------KELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDL 193
            +       KEL     +   KI+++ ++I + +   ++L +++ +L+  +++ E++   +
Sbjct: 1162 IADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKI 1221

Query: 194  DQGTSTEVNTCNEVYELKKKVIERL---EDLCKNVELLSAKLRMYQMEAEDTDS 244
             Q     V T  E+ + K+   + L     L   +E    ++ +Y+++  +  S
Sbjct: 1222 KQ---LLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITS 1272



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 58/280 (20%), Positives = 121/280 (43%), Gaps = 24/280 (8%)

Query: 14  LQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDR--------SDDEDD 65
           L +++  + +Q  + N+   QK+N   G +++ LKE  + D  L++        S+D++ 
Sbjct: 623 LILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEV 682

Query: 66  ISSENPQTDFLHKGMLELEAEHDQ---DLSKQDKQETDV---DEDPQASTSLQF---SKK 116
           +S+E      L++   +L +E  Q   DL     Q+ DV   +   Q    LQ     + 
Sbjct: 683 LSAE---VKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQD 739

Query: 117 NLLELCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDM 176
           NL +L       KL +  T++   +KE+G++  + +E+ D ++  +     ++  + ++ 
Sbjct: 740 NLNKLLENEQVQKL-FVKTQLYGFLKEMGSEVSEDSEEKD-VVNVLQAVGESLAKINEEK 797

Query: 177 LTLKGQ-IEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMY 235
             L  Q  EK+ +   ++       V  C E+  L +   +    L K +E + ++    
Sbjct: 798 CNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEAL 857

Query: 236 QMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRN 275
           Q +  +   +++E+   E    L+     S    KS   N
Sbjct: 858 QSDLLEM-KNANEKTRLENQNLLIQVEEVSQTCSKSEIHN 896


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 14/114 (12%)

Query: 140  QVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTST 199
            Q++E     ++  E++  + KKIN  EN    L    LTL    E +E   L+L Q    
Sbjct: 1135 QLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTL----EHMETERLELAQ---- 1186

Query: 200  EVNTCNEVYELKKKVIER---LEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEI 250
                 NE YE  K + +    L++L K+ E     LR Y  E E T   + EE+
Sbjct: 1187 ---KLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEEL 1237



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 40/192 (20%), Positives = 86/192 (44%), Gaps = 21/192 (10%)

Query: 82   ELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQV 141
            +LEA++ Q L+   K    +++  +  + +Q  +KN L+  L+ +  +     T +    
Sbjct: 1020 DLEAKNTQTLTADVKDNEIIEQQRKIFSLIQ--EKNELQQMLESVIAEKEQLKTDL---- 1073

Query: 142  KELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQI-----------EKLEDRG 190
            KE     I+  E++  +  ++   +  V       +  +G++           EKL+++ 
Sbjct: 1074 KENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKS 1133

Query: 191  LDLDQGTSTEVNTCNEVYELKKKV--IERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSE 248
              L +     +N   E+ E++KK+  IE L++  KN EL    +   ++E     + + E
Sbjct: 1134 QQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYE 1193

Query: 249  EID--TEEMEAL 258
            E+   T+E + L
Sbjct: 1194 EVKSITKERKVL 1205



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 51/262 (19%), Positives = 112/262 (42%), Gaps = 18/262 (6%)

Query: 5   PTNLNNKMSLQMKMDCQEQQLTKK--NNGFFQKLNVTEGAMQDLLKEIIKV-DHILDRSD 61
           P +L   + L+ K+   +++L K+   N   ++  +    ++ L  E+ ++   I D+S+
Sbjct: 709 PKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSE 768

Query: 62  DEDDISSENPQ--TDFLHK-----GMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFS 114
           +   I+SE  +  ++ +HK     G+LE   +   DL+         D++ Q   +L   
Sbjct: 769 ELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMD 828

Query: 115 KKNLLELCLKGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENT--VKSL 172
            +   ++ L+    ++N     +  + ++  +    G  K +   K   + E T  V+  
Sbjct: 829 FEQKYKMVLEENE-RMNQEIVNLSKEAQKFDSSL--GALKTELSYKTQELQEKTREVQER 885

Query: 173 LKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKL 232
           L +M  LK Q+E  +     +++  +       +  E  K + +  +DL +  E L  + 
Sbjct: 886 LNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIER 945

Query: 233 RMYQMEAEDTDSHSSEEIDTEE 254
              + +  DT    +  IDT+E
Sbjct: 946 DQLKSDIHDT---VNMNIDTQE 964


>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
          Length = 1711

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 46/243 (18%), Positives = 112/243 (46%), Gaps = 24/243 (9%)

Query: 6   TNLNNKMSLQMKMDCQEQQLTKKNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDE-D 64
           + LN +M+   ++  Q+Q+++++     +++ V    +  + +E+ + + +    + + D
Sbjct: 578 SELNERMA---ELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLD 634

Query: 65  DISSENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELC-L 123
           D  +E  +   L         EH ++  KQ + E +  +  Q       + ++  E+  +
Sbjct: 635 DAVAEASKERKLR--------EHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKI 686

Query: 124 KGMFLKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQI 183
           K    K      K+    +EL         ++ N+ K+++ +E+   +L K++L LK ++
Sbjct: 687 KSELEK------KVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILMLKDKL 740

Query: 184 EKLE-DRGLDLDQGTSTEVNTCNE----VYELKKKVIERLEDLCKNVELLSAKLRMYQME 238
           EK + +R  ++++   T  +        +++  KK+    E LC  V+ L+A+ R  + E
Sbjct: 741 EKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDE 800

Query: 239 AED 241
            +D
Sbjct: 801 LQD 803


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
           sapiens]
          Length = 638

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 61/266 (22%), Positives = 109/266 (40%), Gaps = 61/266 (22%)

Query: 34  QKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEHDQDLSK 93
           Q+    +  +QDL  E+ K++  L+ +  E    S N  T  L K ++EL          
Sbjct: 10  QERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNAT--LEKQLIEL---------- 57

Query: 94  QDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKI-GLQVKELGADYIDGT 152
                T  +E  ++  S   ++KNL  L L+ M L+ N   TK+ G+  K+ G +     
Sbjct: 58  -----TRTNELLKSKFSENGNQKNLRILSLELMKLR-NKRETKMRGMMAKQEGMEM---- 107

Query: 153 EKIDNIIKKINVTENTVK--------------SLLKDMLTLKGQIEKL------------ 186
                   K+ VT+ +++              S+ K+ +  K + EKL            
Sbjct: 108 --------KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASD 159

Query: 187 --EDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDS 244
             E   LD+ Q         +E+  LK+ + E +  L K VE L+ K ++ + E ED  +
Sbjct: 160 QVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVN 219

Query: 245 HSSEEIDTEEMEALLPQAPASFLVQK 270
            + E    E + A +      F++++
Sbjct: 220 RNREH--NENLNAEMQNLKQKFILEQ 243



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 12/214 (5%)

Query: 22  EQQLTKKNNGFFQKLNVTEGAMQDLLKEI--IKVDHILDRSDDEDDISSENPQTDFLHKG 79
           E+ L +KN+         E  +  L K++  + V   L   + ED ++      + L+  
Sbjct: 172 EENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE 231

Query: 80  MLELEAE---HDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTK 136
           M  L+ +     Q+  K  ++E  +D   Q    L  S    L    + M  + N +  +
Sbjct: 232 MQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEE 291

Query: 137 IGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQG 196
           +   + EL        E+ + ++K++   E   KS  +++  L+   EKL+ +  +L++ 
Sbjct: 292 LKQTLDELDK-LQQKEEQAERLVKQL---EEEAKSRAEELKLLE---EKLKGKEAELEKS 344

Query: 197 TSTEVNTCNEVYELKKKVIERLEDLCKNVELLSA 230
           ++        + E    +++ LED+    E   A
Sbjct: 345 SAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKA 378


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
           sapiens]
          Length = 709

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 61/266 (22%), Positives = 109/266 (40%), Gaps = 61/266 (22%)

Query: 34  QKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEHDQDLSK 93
           Q+    +  +QDL  E+ K++  L+ +  E    S N  T  L K ++EL          
Sbjct: 81  QERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNAT--LEKQLIEL---------- 128

Query: 94  QDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKI-GLQVKELGADYIDGT 152
                T  +E  ++  S   ++KNL  L L+ M L+ N   TK+ G+  K+ G +     
Sbjct: 129 -----TRTNELLKSKFSENGNQKNLRILSLELMKLR-NKRETKMRGMMAKQEGMEM---- 178

Query: 153 EKIDNIIKKINVTENTVK--------------SLLKDMLTLKGQIEKL------------ 186
                   K+ VT+ +++              S+ K+ +  K + EKL            
Sbjct: 179 --------KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASD 230

Query: 187 --EDRGLDLDQGTSTEVNTCNEVYELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDS 244
             E   LD+ Q         +E+  LK+ + E +  L K VE L+ K ++ + E ED  +
Sbjct: 231 QVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVN 290

Query: 245 HSSEEIDTEEMEALLPQAPASFLVQK 270
            + E    E + A +      F++++
Sbjct: 291 RNREH--NENLNAEMQNLKQKFILEQ 314



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 12/214 (5%)

Query: 22  EQQLTKKNNGFFQKLNVTEGAMQDLLKEI--IKVDHILDRSDDEDDISSENPQTDFLHKG 79
           E+ L +KN+         E  +  L K++  + V   L   + ED ++      + L+  
Sbjct: 243 EENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE 302

Query: 80  MLELEAE---HDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTK 136
           M  L+ +     Q+  K  ++E  +D   Q    L  S    L    + M  + N +  +
Sbjct: 303 MQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEE 362

Query: 137 IGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQG 196
           +   + EL        E+ + ++K++   E   KS  +++  L+   EKL+ +  +L++ 
Sbjct: 363 LKQTLDELDK-LQQKEEQAERLVKQL---EEEAKSRAEELKLLE---EKLKGKEAELEKS 415

Query: 197 TSTEVNTCNEVYELKKKVIERLEDLCKNVELLSA 230
           ++        + E    +++ LED+    E   A
Sbjct: 416 SAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKA 449


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 50/234 (21%), Positives = 98/234 (41%), Gaps = 22/234 (9%)

Query: 28   KNNGFFQKLNVTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQTDFLHKGMLELEAEH 87
            +N+    +   TE    +++ + I  + +   S  ED +S      + + +     EAE 
Sbjct: 3413 RNSPVQDEYEFTESLHNEVVPQDILSEELSSESTPEDVLSQGKESFEHISENEFASEAEQ 3472

Query: 88   DQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMFLKLNYWNTKIGLQVKELGAD 147
                ++Q +  ++  E+ Q S+ +   K    +  LK   +    +  K  +       D
Sbjct: 3473 STP-AEQKELGSERKEEDQLSSEVVTEK---AQKELKKSQIDTYCYTCKCPIS----ATD 3524

Query: 148  YIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLEDRGLDLDQGTSTEVNTCNEV 207
             + GT K D+ +  ++   + VK  L + L      E L+++ L ++   S   +  N +
Sbjct: 3525 KVFGTHK-DHEVSTLDTAISAVKVQLAEFL------ENLQEKSLRIEAFVSEIESFFNTI 3577

Query: 208  YELKKKVIERLEDLCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQ 261
             E   K  +RLE+  +N E++   L  Y     D  + S EE+  ++ME L  Q
Sbjct: 3578 EENCSKNEKRLEE--QNEEMMKKVLAQY-----DEKAQSFEEVKKKKMEFLHEQ 3624


>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
          Length = 445

 Score = 35.4 bits (80), Expect = 0.075
 Identities = 42/203 (20%), Positives = 87/203 (42%), Gaps = 40/203 (19%)

Query: 15  QMKMDCQEQQLTKKNNGFFQ-------KLNVTEGAMQDLLKEIIKVDHILDRSDDEDDIS 67
           Q K   +++ L ++ N F +       K+   E ++++  + I ++D +++R + E    
Sbjct: 257 QRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKE---- 312

Query: 68  SENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMF 127
                   L   +LE E E   +L+  DK+     E+  AS   +    + +  C +   
Sbjct: 313 -----RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQK-- 365

Query: 128 LKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLE 187
                       +VK++        E+I+++ KK+   +  +  LL+ +  L+G+  +L+
Sbjct: 366 ------------KVKQM-------VEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQ 406

Query: 188 DRGLDLDQGTSTEVNTCNEVYEL 210
            R   LD  T T+  T  E  E+
Sbjct: 407 SR---LDYLTETQAKTEVETREI 426


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score = 35.4 bits (80), Expect = 0.075
 Identities = 42/203 (20%), Positives = 87/203 (42%), Gaps = 40/203 (19%)

Query: 15  QMKMDCQEQQLTKKNNGFFQ-------KLNVTEGAMQDLLKEIIKVDHILDRSDDEDDIS 67
           Q K   +++ L ++ N F +       K+   E ++++  + I ++D +++R + E    
Sbjct: 257 QRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKE---- 312

Query: 68  SENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMF 127
                   L   +LE E E   +L+  DK+     E+  AS   +    + +  C +   
Sbjct: 313 -----RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQK-- 365

Query: 128 LKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLE 187
                       +VK++        E+I+++ KK+   +  +  LL+ +  L+G+  +L+
Sbjct: 366 ------------KVKQM-------VEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQ 406

Query: 188 DRGLDLDQGTSTEVNTCNEVYEL 210
            R   LD  T T+  T  E  E+
Sbjct: 407 SR---LDYLTETQAKTEVETREI 426


>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
          Length = 466

 Score = 35.4 bits (80), Expect = 0.075
 Identities = 42/203 (20%), Positives = 87/203 (42%), Gaps = 40/203 (19%)

Query: 15  QMKMDCQEQQLTKKNNGFFQ-------KLNVTEGAMQDLLKEIIKVDHILDRSDDEDDIS 67
           Q K   +++ L ++ N F +       K+   E ++++  + I ++D +++R + E    
Sbjct: 257 QRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKE---- 312

Query: 68  SENPQTDFLHKGMLELEAEHDQDLSKQDKQETDVDEDPQASTSLQFSKKNLLELCLKGMF 127
                   L   +LE E E   +L+  DK+     E+  AS   +    + +  C +   
Sbjct: 313 -----RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQK-- 365

Query: 128 LKLNYWNTKIGLQVKELGADYIDGTEKIDNIIKKINVTENTVKSLLKDMLTLKGQIEKLE 187
                       +VK++        E+I+++ KK+   +  +  LL+ +  L+G+  +L+
Sbjct: 366 ------------KVKQM-------VEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQ 406

Query: 188 DRGLDLDQGTSTEVNTCNEVYEL 210
            R   LD  T T+  T  E  E+
Sbjct: 407 SR---LDYLTETQAKTEVETREI 426


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 35.4 bits (80), Expect = 0.075
 Identities = 45/205 (21%), Positives = 97/205 (47%), Gaps = 43/205 (20%)

Query: 22   EQQLTKKNNGFFQKLN-----VTEGAMQDLLKEIIKVDHILDRSDDEDDISSENPQ---- 72
            ++ L ++N    ++++     V EG     L E+ KV  +++    E  ++ E  +    
Sbjct: 1507 QETLRRENKNLQEEISNLTNQVREGTKN--LTEMEKVKKLIEEEKTEVQVTLEETEGALE 1564

Query: 73   ---TDFLH--KGMLELEAEHDQDLSKQD--------KQETDVDE-----DPQASTSLQFS 114
               +  LH    +LE +AE ++ LS++D        KQ+  +D      D +A + ++ +
Sbjct: 1565 RNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVT 1624

Query: 115  K-KNLLELCLKGMFLKLNYWNTKIG----------LQVKELGADYIDGTEKIDNIIKKIN 163
            + K  +E  L  M L+L+  N ++           +Q+K+L     D T+   ++ +++ 
Sbjct: 1625 RLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVA 1684

Query: 164  VTE---NTVKSLLKDMLTLKGQIEK 185
            V E   + ++S L+D+ +L+ Q E+
Sbjct: 1685 VAERRNSLLQSELEDLRSLQEQTER 1709


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,743,153
Number of Sequences: 37866
Number of extensions: 493985
Number of successful extensions: 2911
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 175
Number of HSP's that attempted gapping in prelim test: 2659
Number of HSP's gapped (non-prelim): 439
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.