Search of human proteins with 221554526

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221554526 coiled-coil domain containing 42B [Homo sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221554526 coiled-coil domain containing 42B [Homo sapiens]         600   e-172
gi|226494053 coiled-coil domain containing 42 isoform 1 [Homo sa...   177   1e-44
gi|226528968 coiled-coil domain containing 42 isoform 2 [Homo sa...    93   3e-19
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            60   2e-09
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    57   2e-08
gi|148746195 trichohyalin [Homo sapiens]                               56   4e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    56   5e-08
gi|221139761 zinc finger protein 853 [Homo sapiens]                    54   2e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    53   3e-07
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    51   1e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    51   1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    50   2e-06
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H...    50   2e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        50   3e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        50   3e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         50   3e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         50   3e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         50   3e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         50   3e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         50   3e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         50   3e-06
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    50   3e-06
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]           50   3e-06
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 49   6e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           49   7e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   49   7e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    48   1e-05

>gi|221554526 coiled-coil domain containing 42B [Homo sapiens]
          Length = 308

 Score =  600 bits (1546), Expect = e-172
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MAVPWEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKT 60
           MAVPWEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKT
Sbjct: 1   MAVPWEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKT 60

Query: 61  AALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLW 120
           AALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLW
Sbjct: 61  AALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLW 120

Query: 121 TQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
           TQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR
Sbjct: 121 TQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180

Query: 181 EREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNT 240
           EREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNT
Sbjct: 181 EREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNT 240

Query: 241 AAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQ 300
           AAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQ
Sbjct: 241 AAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQ 300

Query: 301 AEPAAPAS 308
           AEPAAPAS
Sbjct: 301 AEPAAPAS 308


>gi|226494053 coiled-coil domain containing 42 isoform 1 [Homo
           sapiens]
          Length = 316

 Score =  177 bits (449), Expect = 1e-44
 Identities = 107/299 (35%), Positives = 170/299 (56%), Gaps = 4/299 (1%)

Query: 7   EYFRLALQEKLST---KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAAL 63
           EYFRL   E+L     KLP        P + LLEK++E     Q +  +K++F+ +   L
Sbjct: 13  EYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETL 72

Query: 64  KQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQL 123
             RWE+L  KE +LK    + ++F+Q+++ +R RA+++A +ER    +   E  +   ++
Sbjct: 73  NLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEM 132

Query: 124 QELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRERE 183
             LR EH RL  +LK      + LE+ +E    F+E+ E++AR+  L   +  L    +E
Sbjct: 133 VALRLEHQRLSAKLKDYYIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMRHDLMQSAQE 191

Query: 184 QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAE 243
              ++E A+ARL +  +   DE+L Q    A+LQ R + AR   + WES+W  IQNTAA+
Sbjct: 192 GQEKIERAKARLARYMEEKDDEILQQNNELARLQMRFDRARSNVIFWESRWAHIQNTAAK 251

Query: 244 KTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQAE 302
           KTLLLG  +MA LNLFQ+V +H  +   + +EDT  QL+ ++ F+QD S + A + + E
Sbjct: 252 KTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKE 310


>gi|226528968 coiled-coil domain containing 42 isoform 2 [Homo
           sapiens]
          Length = 242

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 78/299 (26%)

Query: 7   EYFRLALQEKLST---KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAAL 63
           EYFRL   E+L     KLP        P + LLEK++E     Q +  +K++F+ +   L
Sbjct: 13  EYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETL 72

Query: 64  KQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQL 123
             RWE+L  KE +LK    + ++F+Q+++                  ++ + A++   + 
Sbjct: 73  NLRWEELGVKEAQLKAHIQKSEQFIQEND------------------QKRIRAMKKANKE 114

Query: 124 QELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRERE 183
           +EL+ +H  +Q   KR +                    E+VA           LRL  + 
Sbjct: 115 RELKCQH--MQELTKRKQ--------------------EMVA-----------LRLEHQR 141

Query: 184 QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAE 243
             A+L+        + + + ++V+   +                   ES+W  IQNTAA+
Sbjct: 142 LSAKLKD-----YYIFNKYLEKVVENSE-------------------ESRWAHIQNTAAK 177

Query: 244 KTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQAE 302
           KTLLLG  +MA LNLFQ+V +H  +   + +EDT  QL+ ++ F+QD S + A + + E
Sbjct: 178 KTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKE 236


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 67/229 (29%), Positives = 105/229 (45%), Gaps = 12/229 (5%)

Query: 13  LQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQ 72
           L  +   +L EQ E       RL E+ + L + ++ L+ Q+E  R +   L ++ E+L +
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252

Query: 73  KERELKGSFIRF---DKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRRE 129
            E  L     R    ++ L++ E R +    R  E+  +   +E    RL  Q + LR +
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEE---RLCEQEERLREQ 309

Query: 130 HARLQRRLKRL-EPCARLLEQALELLPGFQEVPELVARF-DGLAETQAALRLREREQLAE 187
             RL  + +RL E   RL EQ  E LPG + + E V +  +     +   RL ERE+L  
Sbjct: 310 EERLCEQEERLREQEERLCEQ--EKLPGQERLLEEVEKLLEQERRQEEQERLLERERL-- 365

Query: 188 LEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQ 236
           LE     L+Q R    DE L Q +   +L+   E  R   L WE+ + Q
Sbjct: 366 LEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQ 414



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 58/216 (26%), Positives = 98/216 (45%), Gaps = 21/216 (9%)

Query: 39  RQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRA 98
           R+EL    + LQA+ E  +  +   +++ E+L ++E  L+      ++ L++ E R    
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQ----EERLREQEERLCEQ 225

Query: 99  LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL-EPCARLLEQALELLPGF 157
             R  E+  +   +E    RL  Q + LR    RL  + +RL E   RL EQ        
Sbjct: 226 EERLREQEERLREQEE---RLCEQEERLREHEERLCEQEERLCEQEERLREQE------- 275

Query: 158 QEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQ 217
                L  + + L E +   RLRE+E+    +  R R Q+ R    +E L + + R   Q
Sbjct: 276 ---ERLHEQEERLCEQEE--RLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 330

Query: 218 ERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRM 253
           E+L   +ER L+   K ++ +    E+  LL R R+
Sbjct: 331 EKL-PGQERLLEEVEKLLEQERRQEEQERLLERERL 365


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 62/213 (29%), Positives = 101/213 (47%), Gaps = 20/213 (9%)

Query: 24  QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
           QAE        L +KR+E  +  +  +A KE    +   L++  E+  Q+   L+ +  +
Sbjct: 314 QAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQ 373

Query: 84  FDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQ-ELRREHARLQR-RLKRLE 141
            ++ LQ+ E RR R+  R  ++  +   RE E  R   Q + EL+ E A  QR R+K LE
Sbjct: 374 AERLLQEEEERR-RSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELE 432

Query: 142 PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRERE-----QLAELEAAR---- 192
              + L++AL+L        E+ AR D  +   A  RL E E     QL +L+  +    
Sbjct: 433 EMQQRLQEALQL--------EVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYI 484

Query: 193 ARLQQLRDAWPDEVLAQGQRRAQLQERLEAARE 225
            R QQ ++    E+  Q +   Q Q++LE  R+
Sbjct: 485 ERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQ 517



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 5/116 (4%)

Query: 116 ALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQA 175
           A+RL  + +    +  + +RR +R +   R   +  ELL   Q   E   +   L   Q 
Sbjct: 310 AIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQE 369

Query: 176 ALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERL-----EAARER 226
           A R  ER    E E  R++ ++L+ A   ++    Q RA +Q  +     EAAR+R
Sbjct: 370 AQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQR 425


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 68/267 (25%), Positives = 113/267 (42%), Gaps = 46/267 (17%)

Query: 6   EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
           EE  R   QE+   +L  + E+     L+  E+ + L    Q L++++++ R +    ++
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQ----EE 544

Query: 66  RWEQLEQKERELKGSFIRFDKFLQ-DSEARRNRALRRAAEERHQAGRREVEAL---RLWT 121
           R EQL ++E E +    R ++ L+ + E RR++ L+R  E R Q  +RE E     RL  
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604

Query: 122 QLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRE 181
           +  E   +  R ++RLKR EP     +Q L+     +   + + R       Q   R  E
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664

Query: 182 REQLA-------------------ELEAARARLQQLRDAWPDEVLAQ------------- 209
            E+L                    E E AR R++     W  ++ ++             
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724

Query: 210 ---GQRRAQLQERLEAARERTLQWESK 233
              GQRR Q QE     RE  LQW+ +
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEE 751



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 74/254 (29%), Positives = 116/254 (45%), Gaps = 24/254 (9%)

Query: 14  QEKLSTKLPEQAED--HVPPVLRLLEK------RQELVDADQALQAQKEVFRTKTAALK- 64
           +EKL  + P++  +       LR LE+      RQE     Q L+ ++++ R +    + 
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316

Query: 65  QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEE--RHQAGRREVEALRLWTQ 122
           Q+ E+ EQ+ER  +    R  +  ++ E RR + LRR  EE  R Q  RRE E  R   Q
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376

Query: 123 L---QELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALR 178
           L   Q+LRRE   R +++L+R +   R  EQ L      +   +L  R   L   Q   R
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRR--EQQLRREQQLRREQQL-RREQQLRREQEEER 433

Query: 179 LREREQLAELEAARARLQQLRDAW-----PDEVLAQGQRRAQL-QERLEAARERTLQWES 232
             ++ +    E    R Q+ R  W       E   Q +R+ QL +++ E  RER L+ E 
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493

Query: 233 KWIQIQNTAAEKTL 246
           +  + Q    E+ L
Sbjct: 494 EERREQQERREQQL 507



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 63/243 (25%), Positives = 111/243 (45%), Gaps = 24/243 (9%)

Query: 14  QEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQK 73
           QE+   +L  + E+      R   KR+E  +  +  + ++++ R +    ++RW +LE++
Sbjct: 440 QERREQRLKREQEER-----RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494

Query: 74  ERELKGSFIRFDKFLQDSEARRNRALRRAAEERH--------QAGRREVEALR--LWTQL 123
           ER  +    R  +  ++ E RR + L+R  EE          Q  RRE E  R  L  + 
Sbjct: 495 ERREQQER-REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553

Query: 124 QELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRERE 183
           +E R E  R ++RLKR +   R  +Q L+     +E      R     E +   RL+ RE
Sbjct: 554 EEKRLEQERREQRLKREQEERR--DQLLK-----REEERRQQRLKREQEERLEQRLK-RE 605

Query: 184 QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAE 243
           ++  LE    R Q+L+   P+E   Q   +++ QE     + R  Q E +  +++    E
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665

Query: 244 KTL 246
           + L
Sbjct: 666 ERL 668



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 58/224 (25%), Positives = 102/224 (45%), Gaps = 24/224 (10%)

Query: 37  EKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRN 96
           E+R++    +Q L+ ++E  R +    ++  E+L+Q+ R  +       +  ++ E RR 
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ-------QLRREQEERRE 547

Query: 97  RALRRAAEERHQAGRREVEALRLWTQLQE--LRREHARLQRRLKRLEPCARLLEQALELL 154
           + L+R  E+R +  RRE    R   + ++  L+RE  R Q+RLKR +     LEQ L+  
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKR- 604

Query: 155 PGFQEVPELVARFDGLAETQAALRLRE-----REQLAELEAARARLQQLRDAWPDEVLAQ 209
                  E V R +     +  L+  E     R+QL + E    R QQ       E   Q
Sbjct: 605 -------EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657

Query: 210 GQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRM 253
             +R + +ERLE   +R  + E +  ++     E+     +SR+
Sbjct: 658 RLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 52/226 (23%), Positives = 97/226 (42%), Gaps = 14/226 (6%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRT-KTAALK 64
            +E  R   ++K   +  EQ     P   R  E+ ++  + ++  Q ++++ R  +    +
Sbjct: 954  QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQ 124
            Q WE+  +K+ EL+          ++ +  R    +R  +ER +  R E E  +   QL 
Sbjct: 1014 QEWERQYRKKDELQQ---------EEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064

Query: 125  ELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-ERE 183
               RE  R Q   ++      L ++  +LL   +E PE   R +   + +    L+ E E
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLL---REEPEKRRRQERERQCREEEELQQEEE 1121

Query: 184  QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQ 229
            QL   E  + R Q+L   + +E   Q +    L+E  E  R + L+
Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 59/234 (25%), Positives = 97/234 (41%), Gaps = 28/234 (11%)

Query: 5    WEEYFRLA--LQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVF--RTKT 60
            WE  +R    LQ++    L E+ E       R L++R+     ++ LQ ++E      + 
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREK------RRLQERERQYREEEELQQEEEQLLGEERE 1069

Query: 61   AALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLW 120
               +Q  E+  +KE EL+          ++ +  R    +R  +ER +  R E E  +  
Sbjct: 1070 TRRRQELERQYRKEEELQQ---------EEEQLLREEPEKRRRQERERQCREEEELQQEE 1120

Query: 121  TQLQELRREHAR---LQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAAL 177
             QL    RE  R   L+R+ +  E   +  EQ L   P  +   EL  ++    E Q   
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ--- 1177

Query: 178  RLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWE 231
              +E EQL   E  + R ++ R    +E L Q Q+R Q     +   +   QWE
Sbjct: 1178 --QEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWE 1228



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 64/245 (26%), Positives = 109/245 (44%), Gaps = 26/245 (10%)

Query: 5   WEEYF-RLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAAL 63
           W+E   R A +E+L +    + E+   P    L +R+ L    +  + +++  R +   +
Sbjct: 180 WQEREERRAEEEQLQSCKGHETEEF--PDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237

Query: 64  KQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQL 123
            Q  E+ E ++RE      + ++ LQ+ E +R R L+   EE  Q  + E + LR   Q 
Sbjct: 238 FQEEEEKEWRKRETV--LRKEEEKLQEEEPQRQRELQ---EEEEQLRKLERQELRRERQE 292

Query: 124 QELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRERE 183
           +E +++  R +++L+R +   R  +Q        +E  E   R +   E         RE
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQ--------EERREQQERREQQEE--------RRE 336

Query: 184 QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLE--AARERTLQWESKWIQIQNTA 241
           Q    E    R QQLR    +E   Q  RR Q +ER E    RE+ L+ E +  + Q   
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396

Query: 242 AEKTL 246
            E+ L
Sbjct: 397 REQQL 401



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 19/234 (8%)

Query: 33   LRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQ--- 89
            L+  E+ Q+L + +  LQ  +E  R++     Q+W    ++ER+ +   +     LQ   
Sbjct: 840  LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899

Query: 90   ----------DSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKR 139
                      + E +R    +R  +E+ +  R E +  +   QL    RE  R Q R ++
Sbjct: 900  RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959

Query: 140  LEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRL-REREQLAELEAARARLQQL 198
                 +L ++  +LL    E PE   R +   + +    L +E EQL   E  + R Q+ 
Sbjct: 960  YRKDKKLQQKEEQLL---GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016

Query: 199  RDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSR 252
               +  +   Q +    L+E  E  + R  + E ++ + +    E+  LLG  R
Sbjct: 1017 ERQYRKKDELQQEEEQLLRE--EREKRRLQERERQYREEEELQQEEEQLLGEER 1068



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 53/203 (26%), Positives = 89/203 (43%), Gaps = 21/203 (10%)

Query: 34   RLLEKRQELV-DADQALQAQKEVFRTKTAALKQRWEQ-LEQKERELKGSFIRFDKFLQDS 91
            R   K+ EL  + +Q L+ ++E  R +    + R E+ L+Q+E +L G         ++ 
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG---------EER 1068

Query: 92   EARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQAL 151
            E RR + L R   +  +  + E + LR   +  E RR   R +R+ +  E   +  EQ L
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLR---EEPEKRRRQER-ERQCREEEELQQEEEQLL 1124

Query: 152  ELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQ 211
                  +   EL  ++    E Q     +E EQL   E  + R Q+L   + +E   Q +
Sbjct: 1125 REEREKRRRQELERQYREEEEVQ-----QEEEQLLREEPEKRRRQELERQYREEEELQQE 1179

Query: 212  RRAQLQERLEAAR-ERTLQWESK 233
                L+E  E  R ER  Q+  +
Sbjct: 1180 EEQLLREEQEKRRQERERQYREE 1202



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 49/202 (24%), Positives = 95/202 (47%), Gaps = 14/202 (6%)

Query: 23   EQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFI 82
            EQ     P   R  E+ ++  + ++  Q ++++ R +    K+R ++LE++ RE +    
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE--KRRRQELERQYREEEEVQQ 1148

Query: 83   RFDKFLQDS-EARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRR----L 137
              ++ L++  E RR + L R   E  +  + E + LR   + QE RR+    Q R    L
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR---EEQEKRRQERERQYREEEEL 1205

Query: 138  KRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQ 197
            +R +   R  ++       +Q  PE   + + + + +   + RE EQ  +LE ++ R +Q
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQWEPE---KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262

Query: 198  LRDAWPDEVLAQGQRRAQLQER 219
             +      +L + Q R + QER
Sbjct: 1263 SQQDL-QHLLGEQQERDREQER 1283



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 59/220 (26%), Positives = 99/220 (45%), Gaps = 25/220 (11%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQEL--VDADQALQAQKE-VFRTKTAALKQRWEQ-LEQKER 75
            +L EQ         + +E  Q+L   +  Q L+ +++  FR     L++R EQ L ++ER
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641

Query: 76   ELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGR--REVEALRLWTQLQELRREHARL 133
            + K        FL++    R +   R  + RH   R  RE E L    + Q+LRR+    
Sbjct: 1642 DRK--------FLEEEPQLRRQ--EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER-- 1689

Query: 134  QRRLKRLEPCARLLEQALELLPGFQEV--PELVARFDGLAETQAALRLREREQLAELEAA 191
             R+ +  E   R  E+  + L   Q++   EL  +F    E +   +  E+EQL   E  
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF---REEEQLRQETEQEQLRRQERY 1746

Query: 192  RARL--QQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQ 229
            R  L  +QLR    ++ L + +R  + +E  +  +ER  Q
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 54/233 (23%), Positives = 104/233 (44%), Gaps = 34/233 (14%)

Query: 13   LQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK--QRWEQL 70
            LQE+   +L  Q  D      + LE+ Q+L   ++  + +++  R++    K  +  +QL
Sbjct: 1470 LQEREEQQLHRQERDR-----KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524

Query: 71   EQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREH 130
             +++R+ K        FLQ+ +  R +   +   +      RE E LR   + Q+L R+ 
Sbjct: 1525 HRQQRQRK--------FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576

Query: 131  A----RL-QRRLKRLEPCARLL--EQALELLPGFQEVPELVARFDGLAETQAALRLRERE 183
                 RL +++++R E   + +  EQ L    G Q++ +   R     E +  L+ RE +
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ--ERDRKFREDEQLLQEREEQ 1634

Query: 184  QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQ 236
            QL   E  R  L++              RR + +++L   R+R  + E + +Q
Sbjct: 1635 QLHRQERDRKFLEE----------EPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 50/207 (24%), Positives = 96/207 (46%), Gaps = 20/207 (9%)

Query: 23   EQAEDHVPPVLRL-LEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSF 81
            +Q + H P   +L  E+++E    D+  Q +K++ R +    K+R ++ ++K RE     
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE-KRRRQETDRKFREE---- 1341

Query: 82   IRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLE 141
               ++ LQ+ E +  R   R  + R +  R + +  +   + Q LRR+    +R+  + E
Sbjct: 1342 ---EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER--ERKFLKEE 1396

Query: 142  PCARLLEQALELLPG----FQEVPELVARFD---GLAETQAALRLREREQLAELEAARAR 194
               R  E+  +L       F+E  + ++R +      E +  +R +ERE+    E  + R
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456

Query: 195  LQQLRDAWPDEVLAQGQRRAQL--QER 219
             ++ R    +E L Q +   QL  QER
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQER 1483



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 59/225 (26%), Positives = 98/225 (43%), Gaps = 39/225 (17%)

Query: 34   RLLEKRQELVDADQALQAQ---KEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQD 90
            +LL++R+E     Q L  Q   ++    +    +Q  EQ  + +R+ K  F   ++ LQ+
Sbjct: 1626 QLLQEREE-----QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK--FREEEQLLQE 1678

Query: 91   SEA---RRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARL------------QR 135
             E    RR    R+  EE  Q  R+E E   L  + Q  R+E  R             Q 
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738

Query: 136  RLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQL-AELEAARAR 194
            +L+R E   ++LE+  +L P  +E          L   +   + RE EQL  E E  + R
Sbjct: 1739 QLRRQERYRKILEEE-QLRPEREE--------QQLRRQERDRKFREEEQLRQEREEQQLR 1789

Query: 195  LQQL-RDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQ 238
             Q+  R    +E L Q +   QL+ +    R+   +WE + +Q++
Sbjct: 1790 SQESDRKFREEEQLRQEREEQQLRPQ---QRDGKYRWEEEQLQLE 1831



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 46/203 (22%), Positives = 84/203 (41%), Gaps = 16/203 (7%)

Query: 36  LEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQ-DSEAR 94
           L++ +E    +Q L+ + E  R +    +   E+ EQ    +K    ++   L+ +++AR
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAE---EEQEQARERIKSRIPKWQWQLESEADAR 715

Query: 95  RNRALRRAAEERHQAGRREVEALR----LWTQLQELRREHARLQRRLKR--------LEP 142
           +++   R  ++  Q  R+E E  R       Q QE  R H + Q   +R         E 
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEE 775

Query: 143 CARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAW 202
            +    Q L   P  +E  E   R +   + +      E E+       R R ++L+   
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835

Query: 203 PDEVLAQGQRRAQLQERLEAARE 225
            +E L + +R  QLQE  +  +E
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQE 858



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 53/241 (21%), Positives = 92/241 (38%), Gaps = 35/241 (14%)

Query: 14  QEKLSTKLPEQAEDHVPPVLRLLEKRQELV---DADQALQAQKEVFRTKTAALKQRWEQL 70
           + +  ++L  Q E+      +  E+R++      A++  +  ++    +    +QR  QL
Sbjct: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL 798

Query: 71  EQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREH 130
             +ER+      R  +FL + E +  R  +R   E+      E E L+   + Q+L+ E 
Sbjct: 799 RAEERQQ-----REQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853

Query: 131 ARLQRRLKR---------------LEPCARLLEQALELLPGFQEVPELVARFDGLAETQA 175
             LQ   +R               LE   +     L   P  QE          L + Q 
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE---------QLRKEQQ 904

Query: 176 ALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQR---RAQLQERLEAARERTLQWES 232
            L+  E E   E    R R +Q R    +E L Q +    R + ++R    RER  + + 
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964

Query: 233 K 233
           K
Sbjct: 965 K 965



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 41/218 (18%)

Query: 33   LRLLEKRQELVDADQALQAQK--EVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQD 90
            LR  E+ ++ +  +Q L+ Q+    FR +   L+Q  EQ + + +E      R+ K L++
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKFREEEQ-LRQETEQEQLRRQE------RYRKILEE 1752

Query: 91   SEARRNRA---LRRAA------------EERHQAGRREVEALRLWTQLQELRREHARLQR 135
             + R  R    LRR              +ER +   R  E+ R + + ++LR+E    Q 
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812

Query: 136  RLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARL 195
            R ++ +   R  E+ L+L    Q + +           +   + R  EQ A  E +R   
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQ-----------ERDRQYRAEEQFATQEKSRREE 1861

Query: 196  QQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESK 233
            Q+L   W +E   + +RR + + +L     R  Q E +
Sbjct: 1862 QEL---WQEE---EQKRRQERERKLREEHIRRQQKEEQ 1893



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 51/209 (24%), Positives = 90/209 (43%), Gaps = 26/209 (12%)

Query: 13   LQEKLSTKLPEQAEDHV--PPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQL 70
            LQE+    L  Q  D       LR  E+ ++ ++ +Q L+ Q+     +   LK+  +QL
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER----ERKFLKEE-QQL 1399

Query: 71   EQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREH 130
              +ERE +    R  KF ++ +    +   R   E  Q  RR+    +   + Q+LR+E 
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459

Query: 131  ARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEA 190
             R  R  +      +LL++  E     QE      R     E +  LR +ER++      
Sbjct: 1460 HRKFREEE------QLLQEREEQQLHRQE------RDRKFLEEEQQLRRQERDR------ 1501

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQER 219
             + R Q+LR   P+    + +++   Q+R
Sbjct: 1502 -KFREQELRSQEPERKFLEEEQQLHRQQR 1529



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 3/61 (4%)

Query: 178 RLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQI 237
           R   R++  E E  + R Q+ ++   +  LA+G+ +++ QERLE  R+R  + E  W Q 
Sbjct: 121 RFEPRDRQLEEEPGQRRRQKRQEQ--ERELAEGEEQSEKQERLE-QRDRQRRDEELWRQR 177

Query: 238 Q 238
           Q
Sbjct: 178 Q 178


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 63/237 (26%), Positives = 107/237 (45%), Gaps = 26/237 (10%)

Query: 5   WEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
           W +  RL  QE    K+ EQ E       RL E+ +EL + ++ L+ QKE+   +    +
Sbjct: 296 WRQEERLREQEG---KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352

Query: 65  QR---WEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWT 121
           Q    WEQ E+K RE +    R ++ L + E        +   E+ Q  R + E  R+W 
Sbjct: 353 QEEKMWEQ-EEKMREQEEKMWRQEERLWEQE--------KQMREQEQKMRDQEE--RMWE 401

Query: 122 QLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRE 181
           Q + LR +  R++ + K  E   ++ E+        QE  +     D   + Q   R+RE
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREE-----KKMQEQEKKTR--DQEEKMQEEERIRE 454

Query: 182 REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQ 238
           RE+    E    R Q+ +    +E + + + +   Q+RL   +E+   WE + +Q Q
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL--WEQEKMQEQ 509



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 58/237 (24%), Positives = 102/237 (43%), Gaps = 37/237 (15%)

Query: 13  LQEKLSTKLPEQAED--HVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQL 70
           LQEKL     E++E   +V  + R LE+ + L+   Q    Q+E++R +        E+L
Sbjct: 230 LQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE--------EEL 281

Query: 71  EQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREH 130
            ++E++++               +  +  R+    R Q G+   +  ++W Q + LR + 
Sbjct: 282 REQEKKIR--------------KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327

Query: 131 ARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEA 190
             L+ + K L     L EQ  ++    QE  E +   +     Q     R+ E+L E E 
Sbjct: 328 KELREQEKELREQKELREQEEQM----QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 383

Query: 191 A-RARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTL 246
             R + Q++RD        Q +R  +  ERL    ER  + E  W Q++    EK +
Sbjct: 384 QMREQEQKMRD--------QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 48/242 (19%), Positives = 107/242 (44%), Gaps = 33/242 (13%)

Query: 5   WEEYFRLALQEKL---------STKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEV 55
           WE+  ++  QE++           K+ EQ +       ++ E+ +++ D +Q +  Q+E 
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQED-------QMWEQEEKMRDQEQKMWDQEER 566

Query: 56  FRTKTAAL-KQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREV 114
              KT    K+ W+Q E+K RE +    R  K  ++ E  R +  +   +E     + E 
Sbjct: 567 MEKKTQEQEKKTWDQ-EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE- 624

Query: 115 EALRLWTQLQELRREHARL-QRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAET 173
              ++W Q ++++ +  ++ ++  K  E   ++ EQ        Q +PE   +     + 
Sbjct: 625 ---KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ--------QRLPEQKEKLWEHEKM 673

Query: 174 QAALRLREREQ-LAELEAARARLQ-QLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWE 231
           Q   +++E+E+ + E E    + Q Q +  W  E + + +   + ++++    E   + E
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733

Query: 232 SK 233
            K
Sbjct: 734 EK 735


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 76/319 (23%), Positives = 146/319 (45%), Gaps = 37/319 (11%)

Query: 14  QEKLSTKLPEQAED----HVPPVLRLLEKRQEL----VDADQALQAQKEVFRTKTAALKQ 65
           Q++LS    E+ +      + P L+L+ ++Q+L    V   Q LQ Q+E  +T+ A  +Q
Sbjct: 127 QQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ 186

Query: 66  RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
             +Q EQ +++++   +      Q  + ++ + L++  + + Q  +++ E L+   QL  
Sbjct: 187 VLQQQEQLQQQVQEQQLLQQ---QQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLL 243

Query: 126 LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQL 185
           L+++    Q+ L++ +  A+L +Q LE     Q+  +L  +   L + Q  L+ ++++QL
Sbjct: 244 LQQQGQLQQQLLQQQQ--AQLQQQLLE-----QQQAQLQQQL--LLQQQEQLQQQQQQQL 294

Query: 186 AELEAARARLQQLR--DAWPDEV-----------LAQGQRRAQLQERLEAARERTLQWES 232
            + +  + + QQL+     P+E            L   Q   Q ++ LE  +E   Q E 
Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQ 354

Query: 233 KWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKL---FMQ 289
           + +Q++    E   L  +       L Q   Q +  P  L  +  E QLE   +      
Sbjct: 355 RQLQLK-LQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQL 413

Query: 290 DLSAMLAGLGQAEPAAPAS 308
           +L     G G A P APA+
Sbjct: 414 ELVPAAGGGGAAVPGAPAA 432



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 48/218 (22%), Positives = 102/218 (46%), Gaps = 10/218 (4%)

Query: 20  KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKG 79
           +L +Q E    P    L++ Q  ++  Q  Q Q++  +  +   +++ + +  +E + + 
Sbjct: 93  QLEQQPEPQQQPQHEQLQQPQPHLELQQ--QPQQDGQQQLSQLQQEKHQSVHHQELKPEL 150

Query: 80  SFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKR 139
             +   + LQ  + +  + L++  E+      +E + L+   QLQ+  +E   LQ++ ++
Sbjct: 151 QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ 210

Query: 140 LEPCARLLEQALELLPGFQEVPELVARFDGL------AETQAALRLREREQLAE--LEAA 191
           L+    L +Q       FQ+  E + +   L       + Q  L  +++ QL +  LE  
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQ 270

Query: 192 RARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQ 229
           +A+LQQ       E L Q Q++  LQ++ E  +++ LQ
Sbjct: 271 QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 73/308 (23%), Positives = 135/308 (43%), Gaps = 31/308 (10%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAA-LKQRWEQLEQK 73
            EK    L +Q E+    +  L ++ Q   DA   L+   +  + +    L+ R EQ E+K
Sbjct: 1531 EKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK 1590

Query: 74   ERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARL 133
            +R L       +  L+D   R+ RAL  A++++ +   +++EA     Q++   +    +
Sbjct: 1591 KRLLIKQVRELEAELEDE--RKQRALAVASKKKMEIDLKDLEA-----QIEAANKARDEV 1643

Query: 134  QRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALR---LREREQLAELEA 190
             ++L++L+  A++ +   EL        E+ A+     +   +L    L+ +E+LA  E 
Sbjct: 1644 IKQLRKLQ--AQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQL---QERLE---AARERTLQWESKWIQIQNTAAEK 244
            AR   +Q RD   DE+      ++ L   + RLE   A  E  L+ E   +++ N    K
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761

Query: 245  TLLLGRSRMAVLNLFQLVCQ----------HQGQPPTLDIEDTEGQLEHVKLFMQDLSAM 294
            T L   +  A L   +   Q           Q +     +++ EG ++    F   +SA+
Sbjct: 1762 TTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK--SKFKATISAL 1819

Query: 295  LAGLGQAE 302
             A +GQ E
Sbjct: 1820 EAKIGQLE 1827



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 52/194 (26%), Positives = 82/194 (42%), Gaps = 35/194 (18%)

Query: 39   RQELVDADQALQAQKEVFRTKTAALKQRWE----QLEQKERELKGSFIRFDKFLQDSEAR 94
            RQEL  A + L  +    + + A L+ + +    QL +KE EL+G+  R D    D    
Sbjct: 1050 RQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD----DETLH 1105

Query: 95   RNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALELL 154
            +N AL+   E              L  Q+ EL+ +    +    + E   R L + LE L
Sbjct: 1106 KNNALKVVRE--------------LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151

Query: 155  PGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRA 214
                   EL    D  A  Q  LR +  +++AEL+ A     +  +A   ++    QR A
Sbjct: 1152 K-----TELEDTLDTTA-AQQELRTKREQEVAELKKALEEETKNHEA---QIQDMRQRHA 1202

Query: 215  ----QLQERLEAAR 224
                +L E+LE A+
Sbjct: 1203 TALEELSEQLEQAK 1216



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 59/288 (20%), Positives = 123/288 (42%), Gaps = 36/288 (12%)

Query: 11   LALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQL 70
            LALQ +L+    ++ +D +  +  L E +++L+   +AL  + E        L++   +L
Sbjct: 1367 LALQSQLADT-KKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425

Query: 71   EQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREH 130
            +Q+  +L        +   + E ++ +  +  AEE+  + R            +E  R  
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR----------YAEERDRAE 1475

Query: 131  ARLQRRLKRLEPCARLLEQALELLPGFQ--------EVPELVARFDGLAETQAALRLRER 182
            A  + +  +    AR LE+ALE    F+        ++ +L++  D + +    L   +R
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKR 1535

Query: 183  EQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAAR---ERTLQWESKWIQIQN 239
                ++E  R +L++L     DE+ A    + +L+  ++A +   ER LQ        + 
Sbjct: 1536 ALEQQVEEMRTQLEELE----DELQATEDAKLRLEVNMQAMKAQFERDLQTRD-----EQ 1586

Query: 240  TAAEKTLLLGRSRMAVLNL-----FQLVCQHQGQPPTLDIEDTEGQLE 282
               +K LL+ + R     L      + +     +   +D++D E Q+E
Sbjct: 1587 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 48/218 (22%), Positives = 100/218 (45%), Gaps = 16/218 (7%)

Query: 16   KLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKER 75
            +L   L E+ ++H     ++ + RQ    A + L  Q E  +   A L++  + LE   +
Sbjct: 1178 ELKKALEEETKNHEA---QIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234

Query: 76   ELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQR 135
            EL        +   +SE +R + L    +E H A   E + LR+     EL  + ++LQ 
Sbjct: 1235 ELACEVKVLQQVKAESEHKRKK-LDAQVQELH-AKVSEGDRLRV-----ELAEKASKLQN 1287

Query: 136  RLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARL 195
             L  +   + LLE+A +   G +   +  +    L +TQ  L+   R++L  L +   +L
Sbjct: 1288 ELDNV---STLLEEAEK--KGIKFAKDAASLESQLQDTQELLQEETRQKL-NLSSRIRQL 1341

Query: 196  QQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESK 233
            ++ +++  ++   + + R  L++++ A + +    + K
Sbjct: 1342 EEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 50/253 (19%), Positives = 99/253 (39%), Gaps = 9/253 (3%)

Query: 49   LQAQ----KEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAE 104
            LQAQ    +E F ++ A+  +  +Q      EL+      +  L  + A++    +R  E
Sbjct: 1116 LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQE 1175

Query: 105  ERHQAGRREVEALRLWTQLQELRREHA-RLQRRLKRLEPCARLLEQALELLPGFQ-EVPE 162
                    E E      Q+Q++R+ HA  L+   ++LE   R      +   G + +  E
Sbjct: 1176 VAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKE 1235

Query: 163  LVARFDGLAETQAALRLRERE---QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQER 219
            L      L + +A    + ++   Q+ EL A  +   +LR    ++          +   
Sbjct: 1236 LACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTL 1295

Query: 220  LEAARERTLQWESKWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEG 279
            LE A ++ +++      +++   +   LL       LNL   + Q + +  +L  +  E 
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1355

Query: 280  QLEHVKLFMQDLS 292
            +     L  Q L+
Sbjct: 1356 EEARKNLEKQVLA 1368



 Score = 32.0 bits (71), Expect = 0.71
 Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 9/215 (4%)

Query: 37   EKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDK----FLQDSE 92
            +++++L +  +AL+ + E     TAA ++   + EQ+  ELK +     K     +QD  
Sbjct: 1139 KQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR 1198

Query: 93   ARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALE 152
             R   AL   +E+  QA R +     L    Q L  ++  L   +K L+      E   +
Sbjct: 1199 QRHATALEELSEQLEQAKRFKA---NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK 1255

Query: 153  LLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQR 212
             L    +V EL A+       +  L  +  +   EL+     L++               
Sbjct: 1256 KLDA--QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313

Query: 213  RAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
             +QLQ+  E  +E T Q  +   +I+    EK  L
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSL 1348



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 24/120 (20%), Positives = 56/120 (46%), Gaps = 1/120 (0%)

Query: 34   RLLEKRQELVDADQALQ-AQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSE 92
            +L  + +EL    Q L+ A K  F+   +AL+ +  QLE++  +        +K ++ +E
Sbjct: 1789 QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1848

Query: 93   ARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALE 152
             +      +  +ER  A + + +  +   ++++L+R+    +    R     R L++ L+
Sbjct: 1849 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELD 1908


>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 625

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 61/228 (26%), Positives = 98/228 (42%), Gaps = 19/228 (8%)

Query: 28  HVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQ---LEQKERELKGSFIRF 84
           H P   + +E+    V A++ L+   E  R   A +  R ++   L ++     G +   
Sbjct: 325 HSPQTAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQ 384

Query: 85  DKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCA 144
               +    R  R  +RA E+  +A   +VE  R   + +E R    R QR+ +R E   
Sbjct: 385 RVHAKQRREREEREKQRALEQGRRAWAAQVEERR-GRRGREEREAARRRQRQYERSEERR 443

Query: 145 RLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPD 204
           R L +   LL   +E  E  AR D L + Q    L++RE+   L+  R R +Q+R     
Sbjct: 444 RELAERQGLLR--RERAERAAREDRLRKLQQEQNLKQREE--GLQEGRERAEQIR----- 494

Query: 205 EVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSR 252
                 + RAQ   R +  +E  LQ E + +     A  + LL GR+R
Sbjct: 495 ------RERAQRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTR 536



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 22/141 (15%)

Query: 34  RLLEKRQELVDADQALQA----------QKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
           R L +RQ L+  ++A +A          Q++  + +   L++  E+ EQ  RE      R
Sbjct: 444 RELAERQGLLRRERAERAAREDRLRKLQQEQNLKQREEGLQEGRERAEQIRRERAQRAAR 503

Query: 84  FDKFLQDSEARRNRALRRAAEERHQA--------GRREVEALRLWTQLQELRR----EHA 131
             +  +    R  R L RA   RH+A         R+E E LR   +    R     EH 
Sbjct: 504 AKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREGLRSSLEASLGRAQENYEHL 563

Query: 132 RLQRRLKRLEPCARLLEQALE 152
            + R+L+R E   R    ALE
Sbjct: 564 AIGRKLERSEQLTRERRSALE 584


>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 61/228 (26%), Positives = 98/228 (42%), Gaps = 19/228 (8%)

Query: 28  HVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQ---LEQKERELKGSFIRF 84
           H P   + +E+    V A++ L+   E  R   A +  R ++   L ++     G +   
Sbjct: 327 HSPQTAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQ 386

Query: 85  DKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCA 144
               +    R  R  +RA E+  +A   +VE  R   + +E R    R QR+ +R E   
Sbjct: 387 RVHAKQRREREEREKQRALEQGRRAWAAQVEERR-GRRGREEREAARRRQRQYERSEERR 445

Query: 145 RLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPD 204
           R L +   LL   +E  E  AR D L + Q    L++RE+   L+  R R +Q+R     
Sbjct: 446 RELAERQGLLR--RERAERAAREDRLRKLQQEQNLKQREE--GLQEGRERAEQIR----- 496

Query: 205 EVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSR 252
                 + RAQ   R +  +E  LQ E + +     A  + LL GR+R
Sbjct: 497 ------RERAQRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTR 538



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 22/141 (15%)

Query: 34  RLLEKRQELVDADQALQA----------QKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
           R L +RQ L+  ++A +A          Q++  + +   L++  E+ EQ  RE      R
Sbjct: 446 RELAERQGLLRRERAERAAREDRLRKLQQEQNLKQREEGLQEGRERAEQIRRERAQRAAR 505

Query: 84  FDKFLQDSEARRNRALRRAAEERHQA--------GRREVEALRLWTQLQELRR----EHA 131
             +  +    R  R L RA   RH+A         R+E E LR   +    R     EH 
Sbjct: 506 AKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREGLRSSLEASLGRAQENYEHL 565

Query: 132 RLQRRLKRLEPCARLLEQALE 152
            + R+L+R E   R    ALE
Sbjct: 566 AIGRKLERSEQLTRERRSALE 586


>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 61/228 (26%), Positives = 98/228 (42%), Gaps = 19/228 (8%)

Query: 28  HVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQ---LEQKERELKGSFIRF 84
           H P   + +E+    V A++ L+   E  R   A +  R ++   L ++     G +   
Sbjct: 327 HSPQTAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQ 386

Query: 85  DKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCA 144
               +    R  R  +RA E+  +A   +VE  R   + +E R    R QR+ +R E   
Sbjct: 387 RVHAKQRREREEREKQRALEQGRRAWAAQVEERR-GRRGREEREAARRRQRQYERSEERR 445

Query: 145 RLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPD 204
           R L +   LL   +E  E  AR D L + Q    L++RE+   L+  R R +Q+R     
Sbjct: 446 RELAERQGLLR--RERAERAAREDRLRKLQQEQNLKQREE--GLQEGRERAEQIR----- 496

Query: 205 EVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSR 252
                 + RAQ   R +  +E  LQ E + +     A  + LL GR+R
Sbjct: 497 ------RERAQRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTR 538



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 22/141 (15%)

Query: 34  RLLEKRQELVDADQALQA----------QKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
           R L +RQ L+  ++A +A          Q++  + +   L++  E+ EQ  RE      R
Sbjct: 446 RELAERQGLLRRERAERAAREDRLRKLQQEQNLKQREEGLQEGRERAEQIRRERAQRAAR 505

Query: 84  FDKFLQDSEARRNRALRRAAEERHQA--------GRREVEALRLWTQLQELRR----EHA 131
             +  +    R  R L RA   RH+A         R+E E LR   +    R     EH 
Sbjct: 506 AKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREGLRSSLEASLGRAQENYEHL 565

Query: 132 RLQRRLKRLEPCARLLEQALE 152
            + R+L+R E   R    ALE
Sbjct: 566 AIGRKLERSEQLTRERRSALE 586


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 58/219 (26%), Positives = 102/219 (46%), Gaps = 34/219 (15%)

Query: 37  EKRQELVDADQALQAQKEVFRTKTAALKQRWEQL-EQKERELKGSFIRFDKFLQDSEARR 95
           +KR+ L    + ++ ++E    K    ++R EQ+ E+K+++++  F + D+  + ++  R
Sbjct: 562 DKRRRL----EEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 617

Query: 96  ---NRALRRAA----EERHQAGRREVEALRL-WTQLQELRREHARLQRRLKRLEPCARLL 147
               +A ++AA    EE     ++E EA RL W Q +E  R H  L ++ K  E      
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE------ 671

Query: 148 EQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVL 207
                     QE     A    LAE +   R  +  +  E      R Q+ R+   +  L
Sbjct: 672 ----------QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ--ERQL 719

Query: 208 AQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTL 246
           A+ +RR + QERL+A  ER LQ   K +++Q    ++ L
Sbjct: 720 AEQERRRE-QERLQA--ERELQEREKALRLQKEQLQREL 755



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 23/190 (12%)

Query: 34  RLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEA 93
           RL E++ +   A + ++  +   + +  A + RW Q E++ER       R  + LQ  + 
Sbjct: 617 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER-------RHQELLQKKKE 669

Query: 94  RRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALEL 153
                LR+AAE +  A +RE E      + QE RRE  R  R  +R E   +L EQ    
Sbjct: 670 EEQERLRKAAEAKRLAEQREQERREQERREQE-RREQER--REQERREQERQLAEQERR- 725

Query: 154 LPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRR 213
               +E   L A  + L E + ALRL++ +   ELE  + + +Q R       LA+ Q +
Sbjct: 726 ----REQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQR-------LAERQLQ 773

Query: 214 AQLQERLEAA 223
            + +++ + A
Sbjct: 774 EEQEKKAKEA 783



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 14/130 (10%)

Query: 33  LRLLEKRQELVDADQALQAQKEVFR---TKTAALKQRWEQLEQKERELKGSFIRFDKFLQ 89
           LR L++ +E     + LQ +KE  +    K A  K+  EQ EQ+ RE +    R ++  +
Sbjct: 648 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE----RREQERR 703

Query: 90  DSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE----LRREHARLQRRL---KRLEP 142
           + E R      +  +   Q  RRE E L+   +LQE    LR +  +LQR L   K+ E 
Sbjct: 704 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 763

Query: 143 CARLLEQALE 152
             RL E+ L+
Sbjct: 764 QQRLAERQLQ 773


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 58/219 (26%), Positives = 102/219 (46%), Gaps = 34/219 (15%)

Query: 37  EKRQELVDADQALQAQKEVFRTKTAALKQRWEQL-EQKERELKGSFIRFDKFLQDSEARR 95
           +KR+ L    + ++ ++E    K    ++R EQ+ E+K+++++  F + D+  + ++  R
Sbjct: 558 DKRRRL----EEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 613

Query: 96  ---NRALRRAA----EERHQAGRREVEALRL-WTQLQELRREHARLQRRLKRLEPCARLL 147
               +A ++AA    EE     ++E EA RL W Q +E  R H  L ++ K  E      
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE------ 667

Query: 148 EQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVL 207
                     QE     A    LAE +   R  +  +  E      R Q+ R+   +  L
Sbjct: 668 ----------QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ--ERQL 715

Query: 208 AQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTL 246
           A+ +RR + QERL+A  ER LQ   K +++Q    ++ L
Sbjct: 716 AEQERRRE-QERLQA--ERELQEREKALRLQKEQLQREL 751



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 23/190 (12%)

Query: 34  RLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEA 93
           RL E++ +   A + ++  +   + +  A + RW Q E++ER       R  + LQ  + 
Sbjct: 613 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER-------RHQELLQKKKE 665

Query: 94  RRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALEL 153
                LR+AAE +  A +RE E      + QE RRE  R  R  +R E   +L EQ    
Sbjct: 666 EEQERLRKAAEAKRLAEQREQERREQERREQE-RREQER--REQERREQERQLAEQERR- 721

Query: 154 LPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRR 213
               +E   L A  + L E + ALRL++ +   ELE  + + +Q R       LA+ Q +
Sbjct: 722 ----REQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQR-------LAERQLQ 769

Query: 214 AQLQERLEAA 223
            + +++ + A
Sbjct: 770 EEQEKKAKEA 779



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 14/130 (10%)

Query: 33  LRLLEKRQELVDADQALQAQKEVFR---TKTAALKQRWEQLEQKERELKGSFIRFDKFLQ 89
           LR L++ +E     + LQ +KE  +    K A  K+  EQ EQ+ RE +    R ++  +
Sbjct: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE----RREQERR 699

Query: 90  DSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE----LRREHARLQRRL---KRLEP 142
           + E R      +  +   Q  RRE E L+   +LQE    LR +  +LQR L   K+ E 
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759

Query: 143 CARLLEQALE 152
             RL E+ L+
Sbjct: 760 QQRLAERQLQ 769


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 50/236 (21%), Positives = 110/236 (46%), Gaps = 23/236 (9%)

Query: 5   WEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
           W +   L  QEK   K+ +Q E       ++  + + L + +  ++ Q+E  R +   L+
Sbjct: 237 WRQEEELREQEK---KIRKQEE-------KMWRQEERLREQEGKMREQEEKMRRQEKRLR 286

Query: 65  QRWEQLEQKERELK--GSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQ 122
           ++ ++L ++E+EL+        ++ +Q+ E +      +  E+  +  R+E    RLW Q
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE---RLWEQ 343

Query: 123 LQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRER 182
            +++R +  +++ + +      R+ EQ   L    + + E    ++   + Q   R+RER
Sbjct: 344 EKQMREQEQKMRDQEE------RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397

Query: 183 EQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQ 238
           E+    E    R Q+ +    +E + + + +   Q+RL   +E+   WE + +Q Q
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL--WEQEKMQEQ 451



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 22/222 (9%)

Query: 35  LLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEAR 94
           L +K  EL +  +  +++K   +     LK++ E+ +    +++ + ++ + + Q+ E R
Sbjct: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244

Query: 95  RNRALRRAAEE---------RHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCAR 145
                 R  EE         R Q G+   +  ++  Q + LR +   L+ + K L    +
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304

Query: 146 LLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAA-RARLQQLRDAWPD 204
           L EQ  ++    QE  E +   +     Q     R+ E+L E E   R + Q++RD    
Sbjct: 305 LREQEEQM----QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD---- 356

Query: 205 EVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTL 246
               Q +R  +  ERL    ER  + E  W Q +    E+ +
Sbjct: 357 ----QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 50/243 (20%), Positives = 104/243 (42%), Gaps = 25/243 (10%)

Query: 5   WEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
           WE+  ++  QE+   K+  Q E       ++ E+ Q++ D ++ +  Q E  R K   ++
Sbjct: 320 WEQEEKMREQEE---KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376

Query: 65  QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEE---RHQAGRREVEALRLWT 121
           ++ +  EQ+E+            +Q+ E  R R  +   EE   R Q  + + +   +W 
Sbjct: 377 EQEKMWEQEEK------------MQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424

Query: 122 QLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRE 181
           Q +E   +  RL  + ++L    ++ EQ  ++    +++ +    +    +     ++RE
Sbjct: 425 Q-EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483

Query: 182 REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
           +E     +  + R Q+ +  W  E     +R  +  ERL    ER  + +  W Q +   
Sbjct: 484 QEDQMWEQEEKMRDQEQK-MWDQE-----ERMWEQDERLREKEERMREQKKMWQQEEKMR 537

Query: 242 AEK 244
            EK
Sbjct: 538 EEK 540


>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 13/231 (5%)

Query: 21  LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGS 80
           L  Q  DHV  +L L +  Q + +     + + +  R    AL +  E+L  + +E++  
Sbjct: 219 LSRQQGDHVARILELEDDIQTISEKVLTKEVELDRLRDTVKALTREQEKLLGQLKEVQAD 278

Query: 81  FIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
             + +  LQ ++   +       E +     +  +A RL  ++ +++    + Q+R+  L
Sbjct: 279 KEQSEAELQVAQQENHHLNLDLKEAKSWQEEQSAQAQRLKDKVAQMKDTLGQAQQRVAEL 338

Query: 141 EPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAAR-------A 193
           EP    L  A EL    Q+   L+       E  +A   R+R  +AEL  +R        
Sbjct: 339 EPLKEQLRGAQELAASSQQKATLLGE-----ELASAAAARDR-TIAELHRSRLEVAEVNG 392

Query: 194 RLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEK 244
           RL +L     +E     + RA L + +EA +++ L+  ++ ++++    E+
Sbjct: 393 RLAELGLHLKEEKCQWSKERAGLLQSVEAEKDKILKLSAEILRLEKAVQEE 443


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1439 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1498

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1499 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1555

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1556 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1608

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1609 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1657



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1918

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1919 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 1977

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 1978 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2037

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2038 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2097

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2098 VQAEREAAQ 2106



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2422 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2479

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2480 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2529

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2530 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2569

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2570 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2621

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2622 ATKTLPNGRDAL 2633



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2059

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2060 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2105

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2106 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2162

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2163 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2205



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2115 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2174

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2175 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2232

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2352

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2353 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1134 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1193

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1194 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1253

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1254 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1313

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1314 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1370

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1371 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1398



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2543 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2596

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2597 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2656

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2657 RLQEAGILSAEELQRLAQGHTTVDELARR 2685


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1443 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1502

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1503 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1559

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1560 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1612

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1613 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1661



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1868 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1922

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1923 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 1981

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 1982 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2041

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2042 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2101

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2102 VQAEREAAQ 2110



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2426 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2483

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2484 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2533

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2534 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2573

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2574 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2625

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2626 ATKTLPNGRDAL 2637



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1752 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1811

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1812 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1871

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1872 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1931

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1932 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1984



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 2005 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2063

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2064 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2109

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2110 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2166

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2167 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2209



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2119 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2178

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2179 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2236

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2237 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2356

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2357 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2403



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1138 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1197

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1198 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1257

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1258 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1317

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1318 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1374

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1375 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1402



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2547 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2600

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2601 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2660

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2661 RLQEAGILSAEELQRLAQGHTTVDELARR 2689


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1439 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1498

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1499 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1555

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1556 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1608

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1609 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1657



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1918

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1919 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 1977

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 1978 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2037

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2038 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2097

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2098 VQAEREAAQ 2106



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2422 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2479

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2480 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2529

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2530 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2569

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2570 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2621

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2622 ATKTLPNGRDAL 2633



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2059

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2060 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2105

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2106 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2162

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2163 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2205



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2115 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2174

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2175 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2232

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2352

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2353 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1134 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1193

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1194 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1253

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1254 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1313

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1314 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1370

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1371 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1398



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2543 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2596

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2597 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2656

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2657 RLQEAGILSAEELQRLAQGHTTVDELARR 2685


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1407 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1466

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1467 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1523

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1524 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1576

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1577 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1625



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1832 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1886

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1887 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 1945

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 1946 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2005

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2006 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2065

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2066 VQAEREAAQ 2074



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2390 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2447

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2448 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2497

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2498 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2537

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2538 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2589

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2590 ATKTLPNGRDAL 2601



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1716 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1775

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1776 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1835

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1836 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1895

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1896 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1948



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 1969 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2027

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2028 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2073

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2074 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2130

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2131 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2173



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2083 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2142

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2143 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2200

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2201 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2260

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2261 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2320

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2321 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2367



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1102 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1161

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1162 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1221

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1222 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1281

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1282 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1338

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1339 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1366



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2511 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2564

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2565 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2624

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2625 RLQEAGILSAEELQRLAQGHTTVDELARR 2653


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1576 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1635

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1636 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1692

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1693 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1745

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1746 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1794



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 2001 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 2055

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 2056 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 2114

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 2115 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2174

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2175 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2234

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2235 VQAEREAAQ 2243



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2559 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2616

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2617 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2666

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2667 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2706

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2707 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2758

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2759 ATKTLPNGRDAL 2770



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1885 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1944

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1945 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 2004

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 2005 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 2064

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 2065 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2117



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 2138 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2196

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2197 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2242

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2243 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2299

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2300 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2342



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2252 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2311

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2312 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2369

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2370 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2429

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2430 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2489

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2490 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2536



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1271 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1330

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1331 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1390

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1391 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1450

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1451 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1507

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1508 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1535



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2680 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2733

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2734 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2793

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2794 RLQEAGILSAEELQRLAQGHTTVDELARR 2822


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1417 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1476

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1477 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1533

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1534 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1586

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1587 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1635



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1842 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1896

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1897 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 1955

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 1956 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2015

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2016 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2075

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2076 VQAEREAAQ 2084



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2400 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2457

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2458 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2507

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2508 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2547

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2548 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2599

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2600 ATKTLPNGRDAL 2611



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1726 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1785

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1786 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1845

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1846 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1905

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1906 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1958



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 1979 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2037

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2038 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2083

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2084 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2140

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2141 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2183



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2093 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2152

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2153 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2210

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2211 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2270

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2271 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2330

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2331 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2377



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1112 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1171

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1172 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1231

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1232 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1291

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1292 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1348

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1349 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1376



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2521 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2574

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2575 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2634

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2635 RLQEAGILSAEELQRLAQGHTTVDELARR 2663


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1425 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1484

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1485 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1541

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1542 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1594

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1595 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1643



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1850 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1904

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1905 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 1963

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 1964 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2023

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2024 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2083

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2084 VQAEREAAQ 2092



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2408 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2465

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2466 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2515

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2516 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2555

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2556 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2607

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2608 ATKTLPNGRDAL 2619



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1734 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1793

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1794 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1853

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1854 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1913

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1914 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1966



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 1987 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2045

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2046 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2091

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2092 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2148

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2149 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2191



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2101 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2160

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2161 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2218

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2219 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2278

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2279 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2338

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2339 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2385



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1120 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1179

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1180 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1239

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1240 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1299

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1300 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1356

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1357 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1384



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2529 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2582

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2583 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2642

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2643 RLQEAGILSAEELQRLAQGHTTVDELARR 2671


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 34/238 (14%)

Query: 24   QAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIR 83
            QAE      LR+ E+ + +    +A + Q+     +  AL+ R E+ E ++R+ +    R
Sbjct: 1466 QAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER 1525

Query: 84   FDKFLQDSEARRNRA---LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL 140
              + +QD   R+ +A   L    +   +A R +  AL+    L+ELR +    +RRL++ 
Sbjct: 1526 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQ---ALEELRLQAEEAERRLRQA 1582

Query: 141  E-PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            E   AR ++ ALE      E  EL ++    AE  A L       L E   A A+L++  
Sbjct: 1583 EVERARQVQVALETAQRSAEA-ELQSKRASFAEKTAQL----ERSLQEEHVAVAQLRE-- 1635

Query: 200  DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKW-----------IQIQNTAAEKTL 246
                     + +RRAQ Q   E ARE   +   +W           +Q +  A +K+L
Sbjct: 1636 ---------EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1684



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)

Query: 6    EEYFRLALQEKLSTK-LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
            E   RLA  E    + L EQA  H   +   L + ++  D++  L+ QK +       L+
Sbjct: 1891 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSE--LERQKGLVED---TLR 1945

Query: 65   QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALR---LWT 121
            QR  Q+E++   LK SF +      + E    R    A +      + E+EA R   L  
Sbjct: 1946 QR-RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA 2004

Query: 122  QLQELRRE-HARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR 180
            + +  RRE   R+Q+ L   E  AR  + ALE +   +   E   R    AE ++A +L+
Sbjct: 2005 EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQ 2064

Query: 181  EREQLAEL-----EAARARLQQLRDAWPDEVLAQGQR-RAQLQERLEAARERTLQWESKW 234
              ++ A+      E A A   Q ++    + L Q Q    QL+   EAAR    + E   
Sbjct: 2065 LAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEAR 2124

Query: 235  IQIQNTAAE 243
            +Q +  AA+
Sbjct: 2125 VQAEREAAQ 2133



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 49/252 (19%)

Query: 11   LALQEKLST----KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ- 65
            LA QEK++     ++  Q  DH     RL E   EL    + LQ + ++ + K+  ++  
Sbjct: 2449 LATQEKVTLVQTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTV 2506

Query: 66   RWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQE 125
            + EQL Q+ + L+ SF+      +DS  +R R + +   +  Q  + EV       + Q+
Sbjct: 2507 QQEQLLQETQALQQSFLSE----KDSLLQRERFIEQEKAKLEQLFQDEV------AKAQQ 2556

Query: 126  LRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLA----ETQAALRLRE 181
            LR E  R Q++++                   QE   LVA  +       E +  +R R+
Sbjct: 2557 LREEQQRQQQQME-------------------QERQRLVASMEEARRRQHEAEEGVR-RK 2596

Query: 182  REQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTA 241
            +E+L +LE  R +         +E+LA+  +R + Q +L   + R     S+ +     A
Sbjct: 2597 QEELQQLEQQRRQ--------QEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVA 2648

Query: 242  AEKTLLLGRSRM 253
            A KTL  GR  +
Sbjct: 2649 ATKTLPNGRDAL 2660



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 98/233 (42%), Gaps = 36/233 (15%)

Query: 37   EKRQELVDADQALQAQKEVF-----------RTKTAALKQRWEQLEQKERELKGSFIRFD 85
            +KRQEL      ++A+ EV            R+ +   KQR E    + REL     R  
Sbjct: 1775 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1834

Query: 86   KFLQDSEARRNRALRRAAEERHQAGRREV-------EALRLWTQLQELRREHARLQRRLK 138
               ++++ +R  A   AA +R +A R          EA RL T+ +   +E      RL+
Sbjct: 1835 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1894

Query: 139  RLE-----PCARLLEQALELLPGFQE-VPELVARFDGLAETQAAL---RLREREQL-AEL 188
            RL         RL EQA +     +E + +L    D   E Q  L    LR+R Q+  E+
Sbjct: 1895 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1954

Query: 189  EAARARLQQLRDAWPDEVL--------AQGQRRAQLQERLEAARERTLQWESK 233
             A +A  ++      +  L        A+   R++ Q  LEAAR+R L  E +
Sbjct: 1955 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2007



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 62/237 (26%), Positives = 107/237 (45%), Gaps = 33/237 (13%)

Query: 12   ALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLE 71
            A Q K + +  E+ +  V    RL E R E   A Q   AQ+   +   A  K     ++
Sbjct: 2028 ARQRKAALEEVERLKAKVEEARRLRE-RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2086

Query: 72   QKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHA 131
            QKE+EL+ + ++ ++ + D       A RRAAEE  +A    V+A           RE A
Sbjct: 2087 QKEQELQQT-LQQEQSVLDQLRGEAEAARRAAEEAEEA---RVQA----------EREAA 2132

Query: 132  RLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLR-EREQLAELEA 190
            + +R+++  E   RL + A E      +      +    AE +AA R + E+  L + +A
Sbjct: 2133 QSRRQVEEAE---RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQA 2189

Query: 191  ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL 247
            A A +++    + ++ L Q   +AQ+++ L   R          +Q++ T  +K LL
Sbjct: 2190 ADAEMEK-HKKFAEQTLRQ---KAQVEQELTTLR----------LQLEETDHQKNLL 2232



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/287 (22%), Positives = 114/287 (39%), Gaps = 52/287 (18%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELV-DADQALQAQKEVFRTKTAA----------L 63
            E+L     EQA+          + R+E   +A +  QA++   R K AA           
Sbjct: 2142 ERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2201

Query: 64   KQRWEQLEQKERELKGSFIRFD-----KFLQDSEARRNRALRRAAEERHQAGRREVEALR 118
            +Q   Q  Q E+EL    ++ +     K L D E +R +A   A E   Q  + E E   
Sbjct: 2202 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKA--EATEAARQRSQVEEELFS 2259

Query: 119  LWTQLQELRREHARLQRRLKRL----------------EPCARLLEQALELLPGFQEVPE 162
            +  Q++EL +  AR++   + L                E   ++ E+A  L    QE   
Sbjct: 2260 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2319

Query: 163  L-------VARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQ 215
            L       +A+   LAE     +++  ++   L+A    LQQ ++   ++     + + Q
Sbjct: 2320 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2379

Query: 216  L-----------QERLEAARERTLQWESKWIQIQNTAAEKTLLLGRS 251
            +           Q  LEA R+R L+  ++  +++   AE +    R+
Sbjct: 2380 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2426



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/269 (23%), Positives = 112/269 (41%), Gaps = 71/269 (26%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQ-------AQKEVFRTKTAALKQRWE---- 68
            KL  QAE   P    L ++ +   +  + LQ        + E +R + A L +RW+    
Sbjct: 1161 KLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLA 1220

Query: 69   --QLEQKERELKGSFIRFDK--------FLQDSEARRN-----------------RALRR 101
               + Q+E E  G  +R+ +        +LQD+  R+                  R  + 
Sbjct: 1221 QTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQA 1280

Query: 102  AAEERHQAGRREVEALRLWTQ-LQELRREHARLQRRLKRLEPCAR-------------LL 147
              EE  + G +  E  R   Q +  ++    +L     +LEP A              ++
Sbjct: 1281 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1340

Query: 148  EQALELLPGFQEVPELVARF--------------DGLAETQAALRLREREQLAELEAARA 193
            ++ ++L   + E+  L +++              + LAE Q   R  ERE+LAE+EAA  
Sbjct: 1341 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ---RAEERERLAEVEAALE 1397

Query: 194  RLQQLRDAWPDEVLAQGQRRA-QLQERLE 221
            + +QL +A   +  AQ +R A +LQ+R++
Sbjct: 1398 KQRQLAEAHA-QAKAQAEREAKELQQRMQ 1425



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 6    EEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
            +E  RL    + + +   +AE+ V        K++EL   +Q  + Q+E+   +   L++
Sbjct: 2570 QERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLRE 2623

Query: 66   RWEQLEQKER-------ELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEAL 117
            + + LE++ R       E+  S +   K L +  +A    A     E      RR+V A 
Sbjct: 2624 QLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQ 2683

Query: 118  RLW-------TQLQELRREHARLQRRLKR 139
            RL         +LQ L + H  +    +R
Sbjct: 2684 RLQEAGILSAEELQRLAQGHTTVDELARR 2712


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 59/230 (25%), Positives = 102/230 (44%), Gaps = 23/230 (10%)

Query: 13  LQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQ 72
           L  +   +L EQ E       RL E+ + L + ++ L  Q+E  R +   L+++ E+L +
Sbjct: 193 LNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHE 252

Query: 73  KERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHAR 132
           +E  L            + E R      R  E+    G+      RL  ++++L  E  R
Sbjct: 253 QEERLC-----------EQEERLCEQEERLCEQEKLPGQE-----RLLEEVEKLL-EQER 295

Query: 133 LQRRLKRLEPCARLLEQALELLPG--FQEVPELVARFDGLAETQAALRLREREQLAELEA 190
            Q   +RL    RLL++  ELL     ++  E + + + L E +   RLRE E+L ELE 
Sbjct: 296 RQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELE---RLRELERLRELER 352

Query: 191 ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNT 240
            R   + L   W      + + R+  +E L    + TLQ E +  +++ +
Sbjct: 353 LRELERMLELGWEALYEQRAEPRSGFEE-LNNENKSTLQLEQQVKELEKS 401



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 23/211 (10%)

Query: 39  RQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRA 98
           R+EL    + LQA+ E  +  +   +++ E+L ++E  L       ++ L + E R    
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQ----EERLHEQEERLCEQ 225

Query: 99  LRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRL-EPCARLLEQALELLPGF 157
             R  E+  +   +E    RL  Q + L  +  RL  + +RL E   RL EQ  E LPG 
Sbjct: 226 EERLCEQEERLREQEE---RLREQEERLHEQEERLCEQEERLCEQEERLCEQ--EKLPGQ 280

Query: 158 QEVPELVAR-FDGLAETQAALRLREREQLAE-----LEAARARLQQLRDAWPDEVLAQGQ 211
           + + E V +  +     +   RL ERE+L +     LE  R R Q  R  W  E L + +
Sbjct: 281 ERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDER-LWQQETLRELE 339

Query: 212 RRAQLQERLEAARERTLQ------WESKWIQ 236
           R  +L+   E  R R L+      WE+ + Q
Sbjct: 340 RLRELERLRELERLRELERMLELGWEALYEQ 370


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 74/278 (26%), Positives = 109/278 (39%), Gaps = 36/278 (12%)

Query: 19  TKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELK 78
           T L  +    + P+   LE+ Q+LV       +Q      + A L+ +WE+LE    E  
Sbjct: 684 TALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA---RAAELQAQWERLEALAEERA 740

Query: 79  ------GSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHAR 132
                  S  +F     D EA    ALR  +    + G  E          Q L R+H  
Sbjct: 741 QRLAQAASLYQFQADANDMEAWLVDALRLVSSP--ELGHDEFST-------QALARQHRA 791

Query: 133 LQRRLKRLEPCARLL-EQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAA 191
           L+  ++   P    L EQA  L P     PE+  R   L      L+ R  E+   LEAA
Sbjct: 792 LEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQARAGERARALEAA 851

Query: 192 RARLQQLRDA-----WPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTL 246
            A    L +A     W +E   Q      L ERLE       ++E+   ++   AA+ T 
Sbjct: 852 LALYTMLSEAGACGLWVEE-KEQWLNGLALPERLEDLEVVQQRFETLEPEMNTLAAQIT- 909

Query: 247 LLGRSRMAVLNLFQLVCQHQGQPPTLD-IEDTEGQLEH 283
                  AV ++ + +   +  PP  D I +T+ QL H
Sbjct: 910 -------AVNDIAEQLL--KANPPGKDRIVNTQEQLNH 938



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 22/240 (9%)

Query: 15   EKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWE---QLE 71
            ++L+ +  E+ ++H    LRL + R+EL D +Q +Q ++ V    +  L Q +E    L 
Sbjct: 1680 KELAGERRERLQEH----LRLCQLRRELDDLEQWIQEREVV--AASHELGQDYEHVTMLR 1733

Query: 72   QKERELKGSFIRFDKFLQDS-EARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREH 130
             K RE         +   DS  A  N  +      R      +      W  L EL    
Sbjct: 1734 DKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTR 1793

Query: 131  ARLQRRLKRLEPCARLLEQAL-ELLPGFQEVPELVARFDGLAETQAALRLREREQLAELE 189
             ++      L+       QAL  +    Q++P+   R    AE   AL+ R      +++
Sbjct: 1794 GQVLAAAYELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAE---ALQRRHCAYEHDIQ 1850

Query: 190  AARARLQQLR-DAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLL 248
            A   ++QQ++ D    +    G +  ++   ++A  E        W Q+Q ++A +  LL
Sbjct: 1851 ALSPQVQQVQDDGHRLQKAYAGDKAEEIGRHMQAVAE-------AWAQLQGSSAARRQLL 1903


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 62/222 (27%), Positives = 103/222 (46%), Gaps = 42/222 (18%)

Query: 35   LLEKRQELV-DADQALQAQKEVFRTKTAALKQRWEQLEQKER-ELKGSFIRFDKFLQDSE 92
            L EKRQE+  + ++ L   KE  +   A  ++++E  E+K+R EL G      + LQ + 
Sbjct: 836  LREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAH 895

Query: 93   ARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALE 152
             R    +R   +E+H+             +L++LRR H   +R+L+ LE         L+
Sbjct: 896  ERELETVR---QEQHK-------------RLEDLRRRHREQERKLQDLE---------LD 930

Query: 153  LLPGFQEVPELVARFDGLAETQAALRLREREQLAEL--------EAARARLQQLRDAWPD 204
            L    ++V   +A    L E Q     RE++QL ++        E A A  QQL +A  +
Sbjct: 931  LETRAKDVKARLA----LLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKE 986

Query: 205  EVLAQGQRRAQLQERLEAARERTLQWESK--WIQIQNTAAEK 244
                  Q   QL+E L+  + R L+ ES+   +Q Q+   +K
Sbjct: 987  HTHLL-QSNQQLREILDELQARKLKLESQVDLLQAQSQQLQK 1027



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 30/235 (12%)

Query: 11  LALQEKLSTKLPEQAEDHVPPVLR-----LLEKRQELVDADQALQAQKEVFRTKTAALKQ 65
           +A  E+LS    +  E+ V  VL      LLE +QE +   +    Q+E    +   L Q
Sbjct: 581 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEE--EEEILRLHQ 638

Query: 66  RWEQLEQKERELKGSFIRFDKFLQDSEAR-------RNRALRRAAEERHQAGRREVEALR 118
                 QKE+ L     R  K +++ EAR       R   LR   +   QA   ++ A  
Sbjct: 639 ------QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRA-E 691

Query: 119 LWTQLQELRREHARLQR--RLKRLEPCARLLEQALELLPGFQEVPEL---VARFDGLAET 173
               LQ+LR E    Q+  R    +   ++LEQ  E +   ++  +     A+   L + 
Sbjct: 692 QEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQL 751

Query: 174 QAALRLREREQLAELE----AARARLQQLRDAWPDEVLAQGQRRAQLQERLEAAR 224
           +  L    +E +A LE    A   RL    +A   EV++  Q++ Q  ++ E A+
Sbjct: 752 REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ 806



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 66/294 (22%), Positives = 122/294 (41%), Gaps = 55/294 (18%)

Query: 13  LQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQ 72
           L+E+LS  LP +     PP  R L   +E     Q  + Q E            W++ E+
Sbjct: 467 LEERLSPPLPHEERAQSPP--RSLATEEE---PPQGPEGQPE------------WKEAEE 509

Query: 73  KERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELR--REH 130
              +   S +     LQ  +A    A     +E+H             +Q +EL   +E 
Sbjct: 510 LGEDSAAS-LSLQLSLQREQAPSPPAACEKGKEQH-------------SQAEELGPGQEE 555

Query: 131 ARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEA 190
           A        + P   +  +     P     PE ++     A  +A  ++ E++Q   LE+
Sbjct: 556 AEDPEEKVAVSPTPPVSPEVRSTEP--VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLES 613

Query: 191 ARARLQQLRDAW----PDEVLAQGQRRAQ----LQERLEAARE----RTLQWESK---WI 235
            + ++QQLR+       +E+L   Q++ Q    L+ERL+ A E    R  + ES+   W+
Sbjct: 614 KQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWL 673

Query: 236 QIQ---NTAAEKTLLLGRSRMAVLNL-FQLVCQHQGQPPTLDIEDTEGQLEHVK 285
           + Q   +T A++  +      ++  L  +L  Q + +  +L+ ++ +  LE +K
Sbjct: 674 RAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQ-MLEQLK 726



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 20/89 (22%), Positives = 42/89 (47%)

Query: 10   RLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQ 69
            ++AL+ + +T   +Q E+       LL+  Q+L +    LQA+K    ++   L+ + +Q
Sbjct: 965  QVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQ 1024

Query: 70   LEQKERELKGSFIRFDKFLQDSEARRNRA 98
            L++    L+    +    L++     N A
Sbjct: 1025 LQKHFSSLEAEAQKKQHLLREVTVEENNA 1053


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 67/273 (24%), Positives = 121/273 (44%), Gaps = 25/273 (9%)

Query: 34   RLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEA 93
            RLL++ ++L  A + L  ++E+ +      K +WE+ +Q    +  S  +  ++  + E 
Sbjct: 1488 RLLQEEEKLHQAGEKLSPEEEMLQEDK---KLKWEEWKQVWENMLSSKSKEQQYKDEEEV 1544

Query: 94   RRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALEL 153
                 + R  EE+ Q    E   ++   +   + R+ AR +++  + E   R L Q  E 
Sbjct: 1545 TLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE---RKLAQEEEK 1601

Query: 154  LPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQ-GQR 212
            L   QE  +L      LA+    +   +RE +A+ E         + A  +E LAQ G++
Sbjct: 1602 LA--QEERQLAQEERKLAQAYVKITQDDRE-MAQAEG--------KFAQKEETLAQRGEK 1650

Query: 213  RAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRMAVLN-LFQLVCQHQGQPPT 271
             +Q  E+L   R++  +   KW ++     EK    G     V N L Q V +   +   
Sbjct: 1651 LSQEAEKLAQKRKKLAK---KWEKVAR-EEEKLAKKGGKLAEVKNILAQKVEELPQREQN 1706

Query: 272  LDIEDTE--GQLEHVKLFMQDLSAMLAGLGQAE 302
            LD ++ E   +LE ++  M++LS     L Q E
Sbjct: 1707 LDWQEKELAQELEELEWDMEELSWKEEELNQEE 1739



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 54/249 (21%), Positives = 106/249 (42%), Gaps = 24/249 (9%)

Query: 20   KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKG 79
            KL ++AE       +L +K +++   ++ L  +          L Q+ E+L Q+E+ L  
Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709

Query: 80   SFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKR 139
                  + L++ E        +  E   + G       +L  + ++L  E   L  + ++
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEG-------KLVEEKKKLAEEEEALAWQREK 1762

Query: 140  LEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLR 199
            L      L Q  ELL   QE  +L    + + E +  L  R+REQL E    + +L Q R
Sbjct: 1763 LSEEETKLAQEEELL--IQEKEKLAQHKEKMPEEEERLG-RKREQLIE---KKMKLAQKR 1816

Query: 200  DAWPDE---------VLAQGQRRAQLQERLEAARERTLQWESKWIQIQN--TAAEKTLLL 248
            + W +          +L Q +  AQ ++ L   +E+  Q +   +  +   T ++K L+ 
Sbjct: 1817 ERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ 1876

Query: 249  GRSRMAVLN 257
             ++++ + N
Sbjct: 1877 VKNKLGMFN 1885


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 65/305 (21%), Positives = 132/305 (43%), Gaps = 21/305 (6%)

Query: 13   LQEKLSTK---LPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQ 69
            LQ++L  K   L E +E +V  +   L+++Q+++  +     + E  +TK      + EQ
Sbjct: 886  LQKELKIKNHSLQETSEQNVI-LQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQ 944

Query: 70   LEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRR-EVEALRLWTQLQELRR 128
              QK+RE     +R  +   +S A      R+   E     R+ ++E  +   +L ++ +
Sbjct: 945  ELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEK 1004

Query: 129  EHARLQR----RLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQ 184
            E   L+R    +   L     +L+Q    L       + + +     ET+    L++RE 
Sbjct: 1005 EIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREV 1064

Query: 185  L--------AELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESK--- 233
            L         EL++   +LQ+LRD      L+  ++   +++     RE  ++ E K   
Sbjct: 1065 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQE 1124

Query: 234  WIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSA 293
             +++     E+   L +    V +L   + +H+G+     I+  EG LE  +L +++ + 
Sbjct: 1125 LLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIK-LEGTLEKSELELKECNK 1183

Query: 294  MLAGL 298
             +  L
Sbjct: 1184 QIESL 1188



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 44/198 (22%), Positives = 95/198 (47%), Gaps = 21/198 (10%)

Query: 10   RLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTA-------A 62
            +L+L+EK +T + +   +     + + +K+QEL++ DQAL+ +    + + A        
Sbjct: 1094 QLSLEEKYTT-IKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMT 1152

Query: 63   LKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQ 122
            +++   ++EQK  +L+G+  + +  L++   +      +    + Q   +E   L+   +
Sbjct: 1153 IREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQE 1212

Query: 123  LQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRL-RE 181
            + +L++E  R Q+R+K +E   +  EQ             +  ++    +    LRL RE
Sbjct: 1213 ISQLKKEIERTQQRMKEMESVMKEQEQ------------YIATQYKEAIDLGQELRLTRE 1260

Query: 182  REQLAELEAARARLQQLR 199
            + Q +  E A AR QQ++
Sbjct: 1261 QVQNSHTELAEARHQQVQ 1278


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 42/233 (18%), Positives = 116/233 (49%), Gaps = 14/233 (6%)

Query: 13  LQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQ 72
           L ++   K+  Q E       ++ E+ +++ + ++ ++ Q+E+   K   ++++ E + +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341

Query: 73  KERELKGSFIRFDKFLQDSEARRNRALRRAAEE--RHQAGRREVEALRLWTQLQELRREH 130
           KE +++      ++ + + E  R +  +R  EE  R Q  R+E EA ++W Q +++R + 
Sbjct: 342 KEEKIR----ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA-KMWRQEEKIREQE 396

Query: 131 ARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRE---REQLAE 187
            +++ + + ++     + +  E +  +++  E+  + + +   +  +R +E   REQ  +
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKM--WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454

Query: 188 LEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAAR--ERTLQWESKWIQIQ 238
           +      +Q+  +   ++     ++ A++QE+ E  R  E  ++ + K I+ Q
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 40/230 (17%), Positives = 105/230 (45%), Gaps = 17/230 (7%)

Query: 20  KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKG 79
           K+ EQ E        + EK +++   ++ +  ++E  R     + ++ +  EQ+E+  + 
Sbjct: 310 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 369

Query: 80  SFIRFDKFLQDSEARRNRALRRAAEERHQAGRRE-----------VEALRLWTQLQELRR 128
             IR  +  Q+ EA+  R   +  E+  +   +E            +  ++W Q +E++ 
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429

Query: 129 EHARLQRRLKRLEPCARLL----EQALELLPGFQEVPELVARFDG-LAETQAALRLRERE 183
           +  +++R+ +++    + +    E+  E     QE  E +   +G + E +A ++ +E +
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489

Query: 184 QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESK 233
              + E  R + +++R+   +++  Q +   + +E++    E+  + E K
Sbjct: 490 MRRQEEKIREQEKKIREQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 35/225 (15%)

Query: 25  AEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRF 84
           +  H   + R LE + + +   + L  QK   +      +   +QLE + R+L       
Sbjct: 102 SHQHQEALRRELEAQVQTI---RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 158

Query: 85  DKFLQDSEARRNRALRRAAEERHQAGR--------REVEALRLWTQL---QELRREHARL 133
            KF  + E    +AL   A ++ +A R        R+  +L L+      +EL+ ++A+L
Sbjct: 159 WKFAGELE----QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 214

Query: 134 QRRLKRLE-----------PCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRER 182
           Q +L+ +E              R LE+A  LLP  Q    L A  D L +   ++  + +
Sbjct: 215 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ----LQAEADHLGKELQSVSAKLQ 270

Query: 183 EQLAELEA-ARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARER 226
            Q+ E E   R   QQ    W  E   Q +R  ++QE+ E  RE+
Sbjct: 271 AQVEENELWNRLNQQQEEKMWRQEEKIQ-EREEKIQEQEEKIREQ 314



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/138 (15%), Positives = 65/138 (47%), Gaps = 14/138 (10%)

Query: 5   WEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK 64
           WE+   +  QE+   K+  Q E       ++ E+ +++ + ++ +Q Q+E    +   + 
Sbjct: 421 WEQEEEMQEQEE---KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477

Query: 65  QRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEE--RHQAGRREVEALRLWTQ 122
           ++  +++++E +++          Q+ + R      R  EE  R Q    + +  ++W Q
Sbjct: 478 EQEAKMQEQEEKMR---------RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 528

Query: 123 LQELRREHARLQRRLKRL 140
            +++  +  ++Q + +++
Sbjct: 529 EEKMCEQEEKMQEQEEKM 546


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.131    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,795,528
Number of Sequences: 37866
Number of extensions: 450802
Number of successful extensions: 5358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 560
Number of HSP's that attempted gapping in prelim test: 3245
Number of HSP's gapped (non-prelim): 1962
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.