Guide to the Human Genome
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Search of human proteins with 221316602

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316602 peroxisomal carnitine O-octanoyltransferase
isoform 1 [Homo sapiens]
         (640 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform...  1321   0.0  
gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform ...  1249   0.0  
gi|21618331 carnitine acetyltransferase precursor [Homo sapiens]      279   5e-75
gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens]       246   4e-65
gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens]       246   4e-65
gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens]       246   4e-65
gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens]       246   4e-65
gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens]       246   4e-65
gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens]       246   4e-65
gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens]       246   4e-65
gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [H...   229   6e-60
gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [H...   224   1e-58
gi|4503023 carnitine O-palmitoyltransferase precursor [Homo sapi...   222   9e-58
gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo s...   211   2e-54
gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo sa...   211   2e-54
gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo s...   211   2e-54
gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo sap...   211   2e-54
gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo sa...   211   2e-54
gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo s...   199   7e-51
gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo sa...   198   1e-50
gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo s...   197   3e-50
gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo s...   127   3e-29
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]      33   0.62 
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    32   1.8  
gi|91208426 U5 snRNP-specific protein [Homo sapiens]                   32   1.8  
gi|20127408 mitochondrial trifunctional protein, alpha subunit p...    32   1.8  
gi|132814467 glutamyl aminopeptidase [Homo sapiens]                    31   4.0  
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]          30   5.2  
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]           30   5.2  
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap...    30   8.9  

>gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform 1
           [Homo sapiens]
          Length = 640

 Score = 1321 bits (3418), Expect = 0.0
 Identities = 640/640 (100%), Positives = 640/640 (100%)

Query: 1   MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDL 60
           MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDL
Sbjct: 1   MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDL 60

Query: 61  TREGIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD 120
           TREGIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD
Sbjct: 61  TREGIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD 120

Query: 121 VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT 180
           VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT
Sbjct: 121 VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT 180

Query: 181 PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV 240
           PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV
Sbjct: 181 PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV 240

Query: 241 TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS 300
           TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS
Sbjct: 241 TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS 300

Query: 301 LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA 360
           LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA
Sbjct: 301 LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA 360

Query: 361 MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS 420
           MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS
Sbjct: 361 MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS 420

Query: 421 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 480
           DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT
Sbjct: 421 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 480

Query: 481 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 540
           ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL
Sbjct: 481 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 540

Query: 541 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD 600
           IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD
Sbjct: 541 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD 600

Query: 601 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL 640
           RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL
Sbjct: 601 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL 640


>gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform 2
           [Homo sapiens]
          Length = 612

 Score = 1249 bits (3231), Expect = 0.0
 Identities = 612/640 (95%), Positives = 612/640 (95%), Gaps = 28/640 (4%)

Query: 1   MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDL 60
           MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESV                     
Sbjct: 1   MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESV--------------------- 39

Query: 61  TREGIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD 120
                  KPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD
Sbjct: 40  -------KPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLD 92

Query: 121 VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT 180
           VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT
Sbjct: 93  VRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNT 152

Query: 181 PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV 240
           PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV
Sbjct: 153 PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLV 212

Query: 241 TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS 300
           TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS
Sbjct: 213 TPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSS 272

Query: 301 LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA 360
           LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA
Sbjct: 273 LLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDA 332

Query: 361 MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS 420
           MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS
Sbjct: 333 MIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREAS 392

Query: 421 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 480
           DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT
Sbjct: 393 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 452

Query: 481 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 540
           ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL
Sbjct: 453 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 512

Query: 541 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD 600
           IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD
Sbjct: 513 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDD 572

Query: 601 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL 640
           RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL
Sbjct: 573 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL 612


>gi|21618331 carnitine acetyltransferase precursor [Homo sapiens]
          Length = 626

 Score =  279 bits (714), Expect = 5e-75
 Identities = 200/637 (31%), Positives = 317/637 (49%), Gaps = 62/637 (9%)

Query: 16  YQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEE 75
           +QD+LP LPVP L++SL  YL+++                            +P  ++EE
Sbjct: 31  HQDALPRLPVPPLQQSLDHYLKAL----------------------------QPIVSEEE 62

Query: 76  YKKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAG 133
           +  T+++V +FQ+  G+GE+L + L  RA+   NWL EWWL  AYL  R P    V ++ 
Sbjct: 63  WAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPV---VIYSS 119

Query: 134 PAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFST 193
           P              QL   +  +   L++  ++  E +PV  +G  PL MNQ+  + S+
Sbjct: 120 PGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSS 179

Query: 194 CKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIH-EGCLVTPPELLRQLTYI 252
           C+VPG  +D++ N+ +T+   + P HI V+   + F  DV H +G  +T  ++  QL  I
Sbjct: 180 CRVPGPKQDTVSNFSKTK---KPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKI 236

Query: 253 HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPH 312
                     P +  LTS  R  WAKA   LI  D  N   +  IQ S+    ++ + P 
Sbjct: 237 WNSSLQTNKEP-VGILTSNHRNSWAKAYNTLIK-DKVNRDSVRSIQKSIFTVCLDATMPR 294

Query: 313 VTPEDYSEIIAAILIG------DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI 366
           V+ + Y   +A  ++       +   RW DK+   I   +G  G   +HA  +   +V +
Sbjct: 295 VSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTL 354

Query: 367 SYYVDEKIFQNEGRWKGSEKVRD----IPLPEELIFIVDEKVLNDINQAKAQYLREASDL 422
             YV E         K  E VR     +P+P++L F +  ++ +DI +AK        DL
Sbjct: 355 LDYVIEYT-------KKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDL 407

Query: 423 QIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTET 482
            I    F  FGK   K++ L PD FIQ+ALQLAYYR++G     YE+A  R F+ GRT+T
Sbjct: 408 DITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDT 467

Query: 483 MRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIA 542
           +RS +++++ + ++M D SV   ++ + + +A   H         G+ FDRHLLGL L A
Sbjct: 468 IRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQA 527

Query: 543 KEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV--PMVHNGYGFFYHIRDD 600
            E+ + +P++F D  ++ +    +F LSTS V   +   V+   P+V +GYG  Y+  + 
Sbjct: 528 IEDLVSMPDIFMDTSYAIA---MHFHLSTSQVP-AKTDCVMFFGPVVPDGYGVCYNPMEA 583

Query: 601 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNS 637
               + SA+ SC ET+A +L      A  DM  L+ S
Sbjct: 584 HINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS 620


>gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens]
          Length = 630

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 10  ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 41

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 42  RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 98

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 99  AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 158

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 159 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 216

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 217 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 274

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 275 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 334

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 335 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 394

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 395 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 454

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 455 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 514

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 515 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 571

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 572 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603


>gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens]
          Length = 630

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 10  ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 41

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 42  RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 98

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 99  AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 158

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 159 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 216

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 217 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 274

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 275 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 334

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 335 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 394

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 395 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 454

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 455 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 514

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 515 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 571

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 572 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603


>gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens]
          Length = 666

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 46  ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 77

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 78  RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 134

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 135 AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 194

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 195 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 252

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 253 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 310

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 311 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 370

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 371 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 430

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 431 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 490

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 491 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 550

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 551 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 607

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 608 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 639


>gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens]
          Length = 630

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 10  ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 41

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 42  RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 98

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 99  AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 158

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 159 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 216

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 217 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 274

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 275 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 334

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 335 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 394

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 395 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 454

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 455 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 514

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 515 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 571

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 572 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603


>gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens]
          Length = 630

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 10  ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 41

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 42  RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 98

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 99  AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 158

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 159 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 216

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 217 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 274

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 275 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 334

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 335 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 394

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 395 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 454

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 455 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 514

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 515 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 571

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 572 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603


>gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens]
          Length = 630

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 10  ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 41

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 42  RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 98

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 99  AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 158

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 159 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 216

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 217 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 274

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 275 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 334

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 335 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 394

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 395 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 454

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 455 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 514

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 515 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 571

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 572 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603


>gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens]
          Length = 748

 Score =  246 bits (629), Expect = 4e-65
 Identities = 182/632 (28%), Positives = 299/632 (47%), Gaps = 52/632 (8%)

Query: 17  QDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEY 76
           +  LP LPVP L+++L  YL+ +                            +   ++E++
Sbjct: 128 ESGLPKLPVPPLQQTLATYLQCM----------------------------RHLVSEEQF 159

Query: 77  KKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGP 134
           +K++ IVQ+F +  G+GE L QKLLER +   NW+ E+WLN  YL+ R+   +N   + P
Sbjct: 160 RKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVN---SSP 216

Query: 135 AAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH----KVGNTPLDMNQFRML 190
           A  F     P    QL   +  +   L+Y  LL    +P      ++   PL M Q+  L
Sbjct: 217 AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL 276

Query: 191 FSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLT 250
           FS+ ++PG T+D+++   +  S    P H++V C  + FV DV+     ++  +L  QL 
Sbjct: 277 FSSYRLPGHTQDTLVA--QNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLR 334

Query: 251 YIHKKCHSEPDG-PGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS 309
            I K   +E +  P I  LTS+ R+ WA+AR  L+  D  N   L+ I+  + +  + D+
Sbjct: 335 KIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVK-DSTNRDSLDMIERCICLVCL-DA 392

Query: 310 SPHVTPEDYSEIIAAILIG----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVN 365
              V   D    +  +  G    +   RW DKS   +   +G  G  C+H+PFD +++V 
Sbjct: 393 PGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ 452

Query: 366 ISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIA 425
            + ++ + + Q+  +   ++ V ++P P  L +    ++   +  +  +  R   +L   
Sbjct: 453 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI 512

Query: 426 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 485
            Y F ++GK   K +   PD FIQ+ALQLA+YRLH      YE+A  R F  GR + +RS
Sbjct: 513 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS 572

Query: 486 CTVEAVRWCQSMQD--PSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 543
            T EA+ + +++ D   +V   E+   +  A             G   D HLL L  +A+
Sbjct: 573 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR 632

Query: 544 EEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV-PMVHNGYGFFYHIRDDRF 602
                +PE+F D  +  S     FVLSTS V           P+V NGYG  Y+ + +  
Sbjct: 633 AMCKELPEMFMDETYLMS---NRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETI 689

Query: 603 VVACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           +   S++ SC ET + K  +    +  DM  L
Sbjct: 690 LFCISSFHSCKETSSSKFAKAVEESLIDMRDL 721


>gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [Homo
           sapiens]
          Length = 773

 Score =  229 bits (584), Expect = 6e-60
 Identities = 182/641 (28%), Positives = 300/641 (46%), Gaps = 61/641 (9%)

Query: 14  FQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQ 73
           + +Q SLP LPVP++++++ +YL+SV                            +P   +
Sbjct: 165 YSFQTSLPRLPVPAVKDTVNRYLQSV----------------------------RPLMKE 196

Query: 74  EEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAG 133
           E++K+   + Q F  G+G +L   L  ++    N++ +WW    YL  R P  +N N+  
Sbjct: 197 EDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYY- 255

Query: 134 PAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNT-PLDMNQFRMLF 191
            A    +  P     Q  R    +   L Y + L +E++ P+  +G+T PL   Q+  +F
Sbjct: 256 -AMDLLYILPTH--IQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMF 312

Query: 192 STCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTY 251
           +T ++PG   D+I +        R   HIVV  RGR F   + H+G L+ P E+ +Q+  
Sbjct: 313 NTSRIPGEETDTIQHM-------RDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQR 365

Query: 252 I-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSS 310
           I       +P    +AALT+ +R  WA+ R+   G   +N   L+ ++ +    +++++ 
Sbjct: 366 ILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRG-KNKQSLDAVEKAAFFVTLDETE 424

Query: 311 PHVTPED----YSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI 366
                ED          ++L G    RW DKS+  + F NG  G N +H+  DA I+ ++
Sbjct: 425 EGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHL 484

Query: 367 SYYVD-----EKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASD 421
             YV      +  +  +G  KG     +IP P  L + +  +    I  +       A+D
Sbjct: 485 WEYVMSIDSLQLGYAEDGHCKGDINP-NIPYPTRLQWDIPGECQEVIETSLNTANLLAND 543

Query: 422 LQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTE 481
           +   ++ F +FGK + K     PD F+QLALQLA+Y+  G     YE +MTR F  GRTE
Sbjct: 544 VDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTE 603

Query: 482 TMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLI 541
           T+RSCT E+  + ++M DP+  + +R +    A  KH  M +    G G DRHL  L ++
Sbjct: 604 TVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVV 663

Query: 542 AKEEGLPVP---ELFTDP-LFSKSGGGGNFVLSTSLVG---YLRVQGVVVPMVHNGYGFF 594
           +K   +  P   E+ ++P   S S      V    L     Y+   G   P+  +GYG  
Sbjct: 664 SKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVS 723

Query: 595 YHIRDDRFV-VACSAWKSCPETDAEKLVQLTFCAFHDMIQL 634
           Y +  +  +    S+  SCPETD+ +  +    A  D+I L
Sbjct: 724 YILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITL 764


>gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [Homo
           sapiens]
          Length = 756

 Score =  224 bits (572), Expect = 1e-58
 Identities = 177/622 (28%), Positives = 291/622 (46%), Gaps = 61/622 (9%)

Query: 14  FQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQ 73
           + +Q SLP LPVP++++++ +YL+SV                            +P   +
Sbjct: 165 YSFQTSLPRLPVPAVKDTVNRYLQSV----------------------------RPLMKE 196

Query: 74  EEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAG 133
           E++K+   + Q F  G+G +L   L  ++    N++ +WW    YL  R P  +N N+  
Sbjct: 197 EDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYY- 255

Query: 134 PAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNT-PLDMNQFRMLF 191
            A    +  P     Q  R    +   L Y + L +E++ P+  +G+T PL   Q+  +F
Sbjct: 256 -AMDLLYILPTH--IQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMF 312

Query: 192 STCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTY 251
           +T ++PG   D+I +        R   HIVV  RGR F   + H+G L+ P E+ +Q+  
Sbjct: 313 NTSRIPGEETDTIQHM-------RDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQR 365

Query: 252 I-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSS 310
           I       +P    +AALT+ +R  WA+ R+   G   +N   L+ ++ +    +++++ 
Sbjct: 366 ILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRG-KNKQSLDAVEKAAFFVTLDETE 424

Query: 311 PHVTPED----YSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI 366
                ED          ++L G    RW DKS+  + F NG  G N +H+  DA I+ ++
Sbjct: 425 EGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHL 484

Query: 367 SYYVD-----EKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASD 421
             YV      +  +  +G  KG     +IP P  L + +  +    I  +       A+D
Sbjct: 485 WEYVMSIDSLQLGYAEDGHCKGDINP-NIPYPTRLQWDIPGECQEVIETSLNTANLLAND 543

Query: 422 LQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTE 481
           +   ++ F +FGK + K     PD F+QLALQLA+Y+  G     YE +MTR F  GRTE
Sbjct: 544 VDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTE 603

Query: 482 TMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLI 541
           T+RSCT E+  + ++M DP+  + +R +    A  KH  M +    G G DRHL  L ++
Sbjct: 604 TVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVV 663

Query: 542 AKEEGLPVP---ELFTDP-LFSKSGGGGNFVLSTSLVG---YLRVQGVVVPMVHNGYGFF 594
           +K   +  P   E+ ++P   S S      V    L     Y+   G   P+  +GYG  
Sbjct: 664 SKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVS 723

Query: 595 YHIRDDRFV-VACSAWKSCPET 615
           Y +  +  +    S+  SCPET
Sbjct: 724 YILVGENLINFHISSKFSCPET 745


>gi|4503023 carnitine O-palmitoyltransferase precursor [Homo
           sapiens]
          Length = 658

 Score =  222 bits (565), Expect = 9e-58
 Identities = 186/662 (28%), Positives = 307/662 (46%), Gaps = 91/662 (13%)

Query: 13  TFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFAN 72
           T  YQDSLP LP+P LE+++++YL +                             KP  N
Sbjct: 42  TMHYQDSLPRLPIPKLEDTIRRYLSAQ----------------------------KPLLN 73

Query: 73  QEEYKKTEEIVQKFQSGIGEKLHQKL--LERAKGKRNWLEEWWLNVAYLDVRIPSQLNVN 130
             +++KTE+  + F++GIG++LH++L  L++     +++   W ++ YL  R    LN N
Sbjct: 74  DGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDM-YLSARDSVVLNFN 132

Query: 131 FAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRK--------------------- 169
              P   F      +   QL R +      + + + LR                      
Sbjct: 133 ---PFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFK 189

Query: 170 ---EKVP-------VHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNH 219
                VP        + V   PLDM+Q+  LF++ ++P  +RD +     T+ + R   H
Sbjct: 190 RLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELF----TDDKAR---H 242

Query: 220 IVVLCRGRAFVFDVI-HEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAK 278
           ++VL +G  ++FDV+  +G +V+P E+   L YI       P+ P +A LTSE R  WA+
Sbjct: 243 LLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFP-LAYLTSENRDIWAE 301

Query: 279 AREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKS 338
            R+ L+    E    L K+ S++    ++D       +D   +   +L GD T RW DKS
Sbjct: 302 LRQKLMSSGNEES--LRKVDSAVFCLCLDD----FPIKDLVHLSHNMLHGDGTNRWFDKS 355

Query: 339 YNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVR--DIPLPEEL 396
           +NLI   +G    + +H+  D + ++     V +   Q       S+          ++L
Sbjct: 356 FNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKL 415

Query: 397 IFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAY 456
            F + + +   I  AK ++      L I    F   GK+  K + L PD   QLA Q+A+
Sbjct: 416 NFELTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAF 475

Query: 457 YRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQS-MQDPS-VNLRERQQKMLQA 514
            R +G     YE+  T  F HGRTET+R  +V   R  ++ +++PS  +  E QQ M++ 
Sbjct: 476 LRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAGELQQMMVEC 535

Query: 515 FAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLV 574
              H ++ K+ + G+GFDRHL  L  +A  +G+ +PEL+ DP +   G   + VLSTS +
Sbjct: 536 SKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAY---GQINHNVLSTSTL 592

Query: 575 GYLRVQ-GVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQ 633
               V  G   P+V +G+G  Y + D+   + C+   S P  +A + +Q    A  DM  
Sbjct: 593 SSPAVNLGGFAPVVSDGFGVGYAVHDN--WIGCNV-SSYPGRNAREFLQCVEKALEDMFD 649

Query: 634 LM 635
            +
Sbjct: 650 AL 651


>gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score =  211 bits (537), Expect = 2e-54
 Identities = 179/644 (27%), Positives = 287/644 (44%), Gaps = 79/644 (12%)

Query: 4   QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTRE 63
           +L  S     + +Q SLP LPVP +  ++++YLES                         
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES------------------------- 191

Query: 64  GIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRI 123
              V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R 
Sbjct: 192 ---VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRS 248

Query: 124 PSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPL 182
           P  +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+
Sbjct: 249 PLMVNSNY----YVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPM 304

Query: 183 DMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTP 242
              Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F   +     L+ P
Sbjct: 305 CSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLKP 357

Query: 243 PELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSL 301
            +L  Q   I       +P    +AALT+  R  WA+AR+       +N A LE I+ + 
Sbjct: 358 QDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIERAA 416

Query: 302 LVYSMEDSSPHVTPEDYSEII---AAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPF 358
              ++++ S    PED + +     A+L G+   RW DKS+ LISF NG  G N +HA  
Sbjct: 417 FFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWA 476

Query: 359 DAMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKA 413
           DA I+ ++  +V         +   G   G       P P  L + + ++    I  +  
Sbjct: 477 DAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQ 535

Query: 414 QYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTR 473
                A D+++  + F  FGK L K     PD F+Q+ALQLA++R  G     YE +MTR
Sbjct: 536 VAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTR 595

Query: 474 HFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDR 533
            F  GRTET+RSCT E+  + Q+M + S    + +    +A  KH  M +    G G DR
Sbjct: 596 MFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDR 655

Query: 534 HLLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV--------------GY 576
           HL  L L++K  G+  P   E+ ++P          + LSTS +               +
Sbjct: 656 HLFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQHPNH 705

Query: 577 LRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 619
           L   G   P+  +GYG  Y I  +  +    S+  S  ET+A++
Sbjct: 706 LGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 749


>gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score =  211 bits (537), Expect = 2e-54
 Identities = 179/644 (27%), Positives = 287/644 (44%), Gaps = 79/644 (12%)

Query: 4   QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTRE 63
           +L  S     + +Q SLP LPVP +  ++++YLES                         
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES------------------------- 191

Query: 64  GIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRI 123
              V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R 
Sbjct: 192 ---VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRS 248

Query: 124 PSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPL 182
           P  +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+
Sbjct: 249 PLMVNSNY----YVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPM 304

Query: 183 DMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTP 242
              Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F   +     L+ P
Sbjct: 305 CSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLKP 357

Query: 243 PELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSL 301
            +L  Q   I       +P    +AALT+  R  WA+AR+       +N A LE I+ + 
Sbjct: 358 QDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIERAA 416

Query: 302 LVYSMEDSSPHVTPEDYSEII---AAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPF 358
              ++++ S    PED + +     A+L G+   RW DKS+ LISF NG  G N +HA  
Sbjct: 417 FFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWA 476

Query: 359 DAMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKA 413
           DA I+ ++  +V         +   G   G       P P  L + + ++    I  +  
Sbjct: 477 DAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQ 535

Query: 414 QYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTR 473
                A D+++  + F  FGK L K     PD F+Q+ALQLA++R  G     YE +MTR
Sbjct: 536 VAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTR 595

Query: 474 HFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDR 533
            F  GRTET+RSCT E+  + Q+M + S    + +    +A  KH  M +    G G DR
Sbjct: 596 MFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDR 655

Query: 534 HLLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV--------------GY 576
           HL  L L++K  G+  P   E+ ++P          + LSTS +               +
Sbjct: 656 HLFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQHPNH 705

Query: 577 LRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 619
           L   G   P+  +GYG  Y I  +  +    S+  S  ET+A++
Sbjct: 706 LGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 749


>gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score =  211 bits (537), Expect = 2e-54
 Identities = 179/644 (27%), Positives = 287/644 (44%), Gaps = 79/644 (12%)

Query: 4   QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTRE 63
           +L  S     + +Q SLP LPVP +  ++++YLES                         
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES------------------------- 191

Query: 64  GIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRI 123
              V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R 
Sbjct: 192 ---VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRS 248

Query: 124 PSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPL 182
           P  +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+
Sbjct: 249 PLMVNSNY----YVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPM 304

Query: 183 DMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTP 242
              Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F   +     L+ P
Sbjct: 305 CSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLKP 357

Query: 243 PELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSL 301
            +L  Q   I       +P    +AALT+  R  WA+AR+       +N A LE I+ + 
Sbjct: 358 QDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIERAA 416

Query: 302 LVYSMEDSSPHVTPEDYSEII---AAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPF 358
              ++++ S    PED + +     A+L G+   RW DKS+ LISF NG  G N +HA  
Sbjct: 417 FFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWA 476

Query: 359 DAMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKA 413
           DA I+ ++  +V         +   G   G       P P  L + + ++    I  +  
Sbjct: 477 DAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQ 535

Query: 414 QYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTR 473
                A D+++  + F  FGK L K     PD F+Q+ALQLA++R  G     YE +MTR
Sbjct: 536 VAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTR 595

Query: 474 HFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDR 533
            F  GRTET+RSCT E+  + Q+M + S    + +    +A  KH  M +    G G DR
Sbjct: 596 MFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDR 655

Query: 534 HLLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV--------------GY 576
           HL  L L++K  G+  P   E+ ++P          + LSTS +               +
Sbjct: 656 HLFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQHPNH 705

Query: 577 LRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 619
           L   G   P+  +GYG  Y I  +  +    S+  S  ET+A++
Sbjct: 706 LGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 749


>gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score =  211 bits (537), Expect = 2e-54
 Identities = 179/644 (27%), Positives = 287/644 (44%), Gaps = 79/644 (12%)

Query: 4   QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTRE 63
           +L  S     + +Q SLP LPVP +  ++++YLES                         
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES------------------------- 191

Query: 64  GIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRI 123
              V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R 
Sbjct: 192 ---VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRS 248

Query: 124 PSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPL 182
           P  +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+
Sbjct: 249 PLMVNSNY----YVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPM 304

Query: 183 DMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTP 242
              Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F   +     L+ P
Sbjct: 305 CSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLKP 357

Query: 243 PELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSL 301
            +L  Q   I       +P    +AALT+  R  WA+AR+       +N A LE I+ + 
Sbjct: 358 QDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIERAA 416

Query: 302 LVYSMEDSSPHVTPEDYSEII---AAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPF 358
              ++++ S    PED + +     A+L G+   RW DKS+ LISF NG  G N +HA  
Sbjct: 417 FFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWA 476

Query: 359 DAMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKA 413
           DA I+ ++  +V         +   G   G       P P  L + + ++    I  +  
Sbjct: 477 DAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQ 535

Query: 414 QYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTR 473
                A D+++  + F  FGK L K     PD F+Q+ALQLA++R  G     YE +MTR
Sbjct: 536 VAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTR 595

Query: 474 HFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDR 533
            F  GRTET+RSCT E+  + Q+M + S    + +    +A  KH  M +    G G DR
Sbjct: 596 MFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDR 655

Query: 534 HLLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV--------------GY 576
           HL  L L++K  G+  P   E+ ++P          + LSTS +               +
Sbjct: 656 HLFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQHPNH 705

Query: 577 LRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 619
           L   G   P+  +GYG  Y I  +  +    S+  S  ET+A++
Sbjct: 706 LGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 749


>gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score =  211 bits (537), Expect = 2e-54
 Identities = 179/644 (27%), Positives = 287/644 (44%), Gaps = 79/644 (12%)

Query: 4   QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTRE 63
           +L  S     + +Q SLP LPVP +  ++++YLES                         
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES------------------------- 191

Query: 64  GIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRI 123
              V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R 
Sbjct: 192 ---VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRS 248

Query: 124 PSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPL 182
           P  +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+
Sbjct: 249 PLMVNSNY----YVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPM 304

Query: 183 DMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTP 242
              Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F   +     L+ P
Sbjct: 305 CSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLKP 357

Query: 243 PELLRQLTYI-HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSL 301
            +L  Q   I       +P    +AALT+  R  WA+AR+       +N A LE I+ + 
Sbjct: 358 QDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIERAA 416

Query: 302 LVYSMEDSSPHVTPEDYSEII---AAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPF 358
              ++++ S    PED + +     A+L G+   RW DKS+ LISF NG  G N +HA  
Sbjct: 417 FFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWA 476

Query: 359 DAMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKA 413
           DA I+ ++  +V         +   G   G       P P  L + + ++    I  +  
Sbjct: 477 DAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQ 535

Query: 414 QYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTR 473
                A D+++  + F  FGK L K     PD F+Q+ALQLA++R  G     YE +MTR
Sbjct: 536 VAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTR 595

Query: 474 HFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDR 533
            F  GRTET+RSCT E+  + Q+M + S    + +    +A  KH  M +    G G DR
Sbjct: 596 MFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDR 655

Query: 534 HLLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV--------------GY 576
           HL  L L++K  G+  P   E+ ++P          + LSTS +               +
Sbjct: 656 HLFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQHPNH 705

Query: 577 LRVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 619
           L   G   P+  +GYG  Y I  +  +    S+  S  ET+A++
Sbjct: 706 LGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 749


>gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo
           sapiens]
          Length = 792

 Score =  199 bits (506), Expect = 7e-51
 Identities = 184/652 (28%), Positives = 293/652 (44%), Gaps = 91/652 (13%)

Query: 14  FQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQ 73
           F YQ SLP  PVPS++++++KYLESV                            +P  + 
Sbjct: 165 FSYQRSLPRQPVPSVQDTVRKYLESV----------------------------RPILSD 196

Query: 74  EEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAG 133
           E++  T  + Q+F       L   L  ++    N++ +WW    YL  R P  +N N+  
Sbjct: 197 EDFDWTAVLAQEFLRLQASLLQWYLRLKSWWASNYVSDWWEEFVYLRSRNPLMVNSNYYM 256

Query: 134 PAAHFEHYWPPKEGTQLERGSITLW-HNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFS 192
            AA        + G  +   ++ L+ H LN     R+E  P   +G  PL   Q+  +F+
Sbjct: 257 MAA--------RAGNAVH--ALLLYRHRLN-----RQEIPPTLLMGMRPLCSAQYEKIFN 301

Query: 193 TCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYI 252
           T ++PG+ +D I +   ++       H+ V  RGR F         L++P  L +Q   I
Sbjct: 302 TTRIPGVQKDYIRHLHDSQ-------HVAVFHRGRFFRMGTHSRNSLLSPRALEQQFQRI 354

Query: 253 -HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSP 311
                 + P    +AALT+  R  WA+ R     L  +    LE ++ +    S++    
Sbjct: 355 LDDPSPACPHEEHLAALTAAPRGTWAQVRT---SLKTQAAEALEAVEGAAFFVSLDAEPA 411

Query: 312 HVTPEDYSEIIAA----ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI- 366
            +T ED +  + A    +L G    RW DKS+ LI FSNG  G + +H+  D  I  ++ 
Sbjct: 412 GLTREDPAASLDAYAHALLAGRGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMW 471

Query: 367 SYYVDEKIFQ----NEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAK--AQYLREAS 420
            + +  + FQ     +G  KG      +P P+ L + + +++ + I+ A   A+ L E  
Sbjct: 472 EFTLATECFQLGYSTDGHCKGHPDPT-LPQPQRLQWDLPDQIHSSISLALRGAKILSENV 530

Query: 421 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 480
           D  +    F+ FGK   +   L  D+FIQ+ALQLA++R  G     YE+AMTR F  GRT
Sbjct: 531 DCHVVP--FSLFGKSFIRRCHLSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRT 588

Query: 481 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 540
           ET+RSCT EA  + ++M+D      +       A  KH  ++K   +G+G DRHL  L +
Sbjct: 589 ETVRSCTREACNFVRAMEDKEKTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALYI 648

Query: 541 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPM 586
           +++   L  P  F   + S+      + LSTS +               Y+   G   P 
Sbjct: 649 VSRFLHLQSP--FLTQVHSE-----QWQLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPA 701

Query: 587 VHNGYGFFYHIRDDRFVV-ACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNS 637
             +GYG  Y    D  +    S+ KS  +TD+ +L Q    A  D+  L  +
Sbjct: 702 DDHGYGVSYIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDALLDVASLFQA 753


>gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo
           sapiens]
          Length = 803

 Score =  198 bits (503), Expect = 1e-50
 Identities = 180/652 (27%), Positives = 290/652 (44%), Gaps = 80/652 (12%)

Query: 14  FQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQ 73
           F YQ SLP  PVPS++++++KYLESV                            +P  + 
Sbjct: 165 FSYQRSLPRQPVPSVQDTVRKYLESV----------------------------RPILSD 196

Query: 74  EEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAG 133
           E++  T  + Q+F       L   L  ++    N++ +WW    YL  R P  +N N+  
Sbjct: 197 EDFDWTAVLAQEFLRLQASLLQWYLRLKSWWASNYVSDWWEEFVYLRSRNPLMVNSNYY- 255

Query: 134 PAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVP-VHKVGNTPLDMNQFRMLFS 192
                +  +      Q  R    +   L Y   L ++++P    +G  PL   Q+  +F+
Sbjct: 256 ---MMDFLYVTPTPLQAARAGNAVHALLLYRHRLNRQEIPPTLLMGMRPLCSAQYEKIFN 312

Query: 193 TCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYI 252
           T ++PG+ +D I +   ++       H+ V  RGR F         L++P  L +Q   I
Sbjct: 313 TTRIPGVQKDYIRHLHDSQ-------HVAVFHRGRFFRMGTHSRNSLLSPRALEQQFQRI 365

Query: 253 -HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSP 311
                 + P    +AALT+  R  WA+ R     L  +    LE ++ +    S++    
Sbjct: 366 LDDPSPACPHEEHLAALTAAPRGTWAQVRT---SLKTQAAEALEAVEGAAFFVSLDAEPA 422

Query: 312 HVTPEDYSEIIAA----ILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI- 366
            +T ED +  + A    +L G    RW DKS+ LI FSNG  G + +H+  D  I  ++ 
Sbjct: 423 GLTREDPAASLDAYAHALLAGRGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMW 482

Query: 367 SYYVDEKIFQ----NEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAK--AQYLREAS 420
            + +  + FQ     +G  KG      +P P+ L + + +++ + I+ A   A+ L E  
Sbjct: 483 EFTLATECFQLGYSTDGHCKGHPDPT-LPQPQRLQWDLPDQIHSSISLALRGAKILSENV 541

Query: 421 DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRT 480
           D  +    F+ FGK   +   L  D+FIQ+ALQLA++R  G     YE+AMTR F  GRT
Sbjct: 542 DCHVVP--FSLFGKSFIRRCHLSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRT 599

Query: 481 ETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLL 540
           ET+RSCT EA  + ++M+D      +       A  KH  ++K   +G+G DRHL  L +
Sbjct: 600 ETVRSCTREACNFVRAMEDKEKTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALYI 659

Query: 541 IAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPM 586
           +++   L  P  F   + S+      + LSTS +               Y+   G   P 
Sbjct: 660 VSRFLHLQSP--FLTQVHSE-----QWQLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPA 712

Query: 587 VHNGYGFFYHIRDDRFVV-ACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNS 637
             +GYG  Y    D  +    S+ KS  +TD+ +L Q    A  D+  L  +
Sbjct: 713 DDHGYGVSYIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDALLDVASLFQA 764


>gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo
           sapiens]
          Length = 738

 Score =  197 bits (500), Expect = 3e-50
 Identities = 167/583 (28%), Positives = 266/583 (45%), Gaps = 55/583 (9%)

Query: 67  VKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQ 126
           V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R P  
Sbjct: 158 VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLM 217

Query: 127 LNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPLDMN 185
           +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+   
Sbjct: 218 VNSNYYV----MDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSY 273

Query: 186 QFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPEL 245
           Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F   +     L+ P +L
Sbjct: 274 QMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFFKLWLYEGARLLKPQDL 326

Query: 246 LRQLTYIHKKCHSEPDGPG---IAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLL 302
             Q   I       P  PG   +AALT+  R  WA+AR+       +N A LE I+ +  
Sbjct: 327 EMQFQRILDD--PSPPQPGEEKLAALTAGGRVEWAQARQAFFS-SGKNKAALEAIERAAF 383

Query: 303 VYSMEDSSPHVTPEDYSEIIA---AILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFD 359
             ++++ S    PED + +     A+L G+   RW DKS+ LISF NG  G N +HA  D
Sbjct: 384 FVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWAD 443

Query: 360 AMIMVNISYYV-----DEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQ 414
           A I+ ++  +V         +   G   G       P P  L + + ++    I  +   
Sbjct: 444 APIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQV 502

Query: 415 YLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRH 474
               A D+++  + F  FGK L K     PD F+Q+ALQLA++R  G     YE +MTR 
Sbjct: 503 AKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRM 562

Query: 475 FYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRH 534
           F  GRTET+RSCT E+  + Q+M + S    + +    +A  KH  M +    G G DRH
Sbjct: 563 FREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRH 622

Query: 535 LLGLLLIAKEEGLPVP---ELFTDPLFSKSGGGGNFVLSTSLV--------------GYL 577
           L  L L++K  G+  P   E+ ++P          + LSTS +               +L
Sbjct: 623 LFCLYLVSKYLGVSSPFLAEVLSEP----------WRLSTSQIPQSQIRMFDPEQHPNHL 672

Query: 578 RVQGVVVPMVHNGYGFFYHIRDDRFV-VACSAWKSCPETDAEK 619
              G   P+  +GYG  Y I  +  +    S+  S  ET+A++
Sbjct: 673 GAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQR 715


>gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo
           sapiens]
          Length = 691

 Score =  127 bits (319), Expect = 3e-29
 Identities = 100/319 (31%), Positives = 149/319 (46%), Gaps = 34/319 (10%)

Query: 324 AILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYV-----DEKIFQNE 378
           A+L G+   RW DKS+ LISF NG  G N +HA  DA I+ ++  +V         +   
Sbjct: 361 ALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTET 420

Query: 379 GRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTK 438
           G   G       P P  L + + ++    I  +       A D+++  + F  FGK L K
Sbjct: 421 GHCLGKPNPALAP-PTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIK 479

Query: 439 NKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQ 498
                PD F+Q+ALQLA++R  G     YE +MTR F  GRTET+RSCT E+  + Q+M 
Sbjct: 480 KCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMM 539

Query: 499 DPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVP---ELFTD 555
           + S    + +    +A  KH  M +    G G DRHL  L L++K  G+  P   E+ ++
Sbjct: 540 EGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSE 599

Query: 556 PLFSKSGGGGNFVLSTSLV--------------GYLRVQGVVVPMVHNGYGFFYHIRDDR 601
           P          + LSTS +               +L   G   P+  +GYG  Y I  + 
Sbjct: 600 P----------WRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGEN 649

Query: 602 FV-VACSAWKSCPETDAEK 619
            +    S+  S  ET+A++
Sbjct: 650 TIFFHISSKFSSSETNAQR 668



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 55/227 (24%), Positives = 97/227 (42%), Gaps = 40/227 (17%)

Query: 4   QLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTRE 63
           +L  S     + +Q SLP LPVP +  ++++YLES                         
Sbjct: 157 RLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES------------------------- 191

Query: 64  GIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRI 123
              V+P  + EEY + E + ++FQ     +L + L+ ++    N++ +WW    YL  R 
Sbjct: 192 ---VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRS 248

Query: 124 PSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKV-PVHKVGNTPL 182
           P  +N N+       +         Q  R    +   + Y + L +E++ PV  +G  P+
Sbjct: 249 PLMVNSNY----YVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPM 304

Query: 183 DMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAF 229
              Q   +F+T ++PG   D + +     S+ R   H+ V  +GR F
Sbjct: 305 CSYQMERMFNTTRIPGKDTDVLQHL----SDSR---HVAVYHKGRFF 344


>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
          Length = 2539

 Score = 33.5 bits (75), Expect = 0.62
 Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 6/88 (6%)

Query: 235 HEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGL-DPENLAL 293
           H  C      L   L    +  +     PG A L S   T  A+ ++YL  + D   L L
Sbjct: 518 HSQCQDCKDSLSEDLASATEPANDSLSSPGAANLFS---TYLARCQQYLCSIPDSLCLEL 574

Query: 294 LEKIQSSLLVYSME-DSSPHVTPEDYSE 320
           LE I S LL+ S +    PH+ PEDY+E
Sbjct: 575 LENIFSLLLITSADLHPEPHL-PEDYAE 601


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 51/196 (26%), Positives = 79/196 (40%), Gaps = 21/196 (10%)

Query: 28  LEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEYKKTEEIVQKFQ 87
           LEE +  Y E + +   ++R L     RGF   +   ++V  F      KK EE+    Q
Sbjct: 631 LEEEIIAYEERMKKLNTELRKL-----RGFHQESE--LEVHAFD-----KKLEEM--SCQ 676

Query: 88  SGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEG 147
               +K HQ  L+    K   L E+   +A L   +          P      +  PK+ 
Sbjct: 677 VLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLP-----QWSVPKDT 731

Query: 148 TQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNY 207
            +L RG+  +  NL  W   +++KV   K+GN   +  ++    S  K    TR S  N 
Sbjct: 732 CRLYRGNDQIMTNLEQW--AKQQKVANEKLGNQLREQVKYIAKLSGEKDREPTRASSPNT 789

Query: 208 FRTESEGRSPNHIVVL 223
            R  S   S  H V++
Sbjct: 790 TRPSSPSHSHLHSVMV 805


>gi|91208426 U5 snRNP-specific protein [Homo sapiens]
          Length = 2335

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 24/136 (17%)

Query: 278  KAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDK 337
            +A   ++  +P    L E+I+  L +YS E + P+++ ++Y E+ +  +I      W   
Sbjct: 1728 QAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQII------WFVD 1781

Query: 338  SYNLISFS-NGVFGCNCDHAPFDAMI-------------MVNISYYVDEKIFQNEGRWKG 383
              N+   + +  F  N    P +  I             +++ S +  +K      +WK 
Sbjct: 1782 DTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKT 1841

Query: 384  SEKV----RDIPLPEE 395
            +E+V    R +P+ E+
Sbjct: 1842 AEEVAALIRSLPVEEQ 1857


>gi|20127408 mitochondrial trifunctional protein, alpha subunit
           precursor [Homo sapiens]
          Length = 763

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 21  PSLPVPSLEESLKKYLESVTRTCYQ---IRGLDPDAKRGFLDLTREGIQVKPFANQEEYK 77
           P L  P  EE   +YLE V  T  +    + + P   +G ++         PF  Q+ YK
Sbjct: 227 PGLKPP--EERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYK 284

Query: 78  KTEEIVQKFQSGI 90
           K EE V+K   G+
Sbjct: 285 KVEEKVRKQTKGL 297


>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
          Length = 957

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 8/57 (14%)

Query: 68  KPFANQEEYKKTEEIVQKF-QSGIGEKLHQKLLERAKGKRNWLE-------EWWLNV 116
           +PF  + +  + E    K+ Q+G GEK  +++LE  K    WL+       EW+ N+
Sbjct: 897 EPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNL 953


>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
          Length = 1456

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 14/46 (30%), Positives = 24/46 (52%)

Query: 265  IAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSS 310
            I     EER  W +AR+  IG     +++  + + + L Y M+DS+
Sbjct: 959  IFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDST 1004


>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
          Length = 1456

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 14/46 (30%), Positives = 24/46 (52%)

Query: 265  IAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSS 310
            I     EER  W +AR+  IG     +++  + + + L Y M+DS+
Sbjct: 959  IFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDST 1004


>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 29.6 bits (65), Expect = 8.9
 Identities = 12/42 (28%), Positives = 22/42 (52%)

Query: 63  EGIQVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKG 104
           E +   P   QEE+K+  + +Q+ Q  + +  HQK +   +G
Sbjct: 167 ERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEG 208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,884,736
Number of Sequences: 37866
Number of extensions: 1198877
Number of successful extensions: 2551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2397
Number of HSP's gapped (non-prelim): 53
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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