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Search of human proteins with 221139764
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
(1648 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 3300 0.0
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 176 2e-43
gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 128 5e-29
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 103 1e-21
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 103 1e-21
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 98 6e-20
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 98 6e-20
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 90 2e-17
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 89 3e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 84 9e-16
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 84 9e-16
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 84 1e-15
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 82 6e-15
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 79 5e-14
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 78 6e-14
gi|50962882 G patch domain containing 8 [Homo sapiens] 77 1e-13
gi|52426743 cisplatin resistance-associated overexpressed protei... 77 2e-13
gi|19923485 cisplatin resistance-associated overexpressed protei... 77 2e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 75 7e-13
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 75 7e-13
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 74 9e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 73 2e-12
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 73 3e-12
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 73 3e-12
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 73 3e-12
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 73 3e-12
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 73 3e-12
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 72 3e-12
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 72 6e-12
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 72 6e-12
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 3300 bits (8557), Expect = 0.0
Identities = 1648/1648 (100%), Positives = 1648/1648 (100%)
Query: 1 MDDDSLDELVARSPGPDGHPQVGPADPAGDFEESSVGSSGDSGDDSDSEHGDGTDGEDEG 60
MDDDSLDELVARSPGPDGHPQVGPADPAGDFEESSVGSSGDSGDDSDSEHGDGTDGEDEG
Sbjct: 1 MDDDSLDELVARSPGPDGHPQVGPADPAGDFEESSVGSSGDSGDDSDSEHGDGTDGEDEG 60
Query: 61 ASEEEDLEDRSGSEDSEDDGETLLEVAGTQGKLEAAGSFNSDDDAESCPICLNAFRDQAV 120
ASEEEDLEDRSGSEDSEDDGETLLEVAGTQGKLEAAGSFNSDDDAESCPICLNAFRDQAV
Sbjct: 61 ASEEEDLEDRSGSEDSEDDGETLLEVAGTQGKLEAAGSFNSDDDAESCPICLNAFRDQAV 120
Query: 121 GTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGGKILRKIPVENTKASEEE 180
GTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGGKILRKIPVENTKASEEE
Sbjct: 121 GTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGGKILRKIPVENTKASEEE 180
Query: 181 EDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAAPGVVLAAD 240
EDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAAPGVVLAAD
Sbjct: 181 EDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAAPGVVLAAD 240
Query: 241 AGPVSEEEVSLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHT 300
AGPVSEEEVSLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHT
Sbjct: 241 AGPVSEEEVSLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHT 300
Query: 301 PGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAK 360
PGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAK
Sbjct: 301 PGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAK 360
Query: 361 SKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLG 420
SKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLG
Sbjct: 361 SKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLG 420
Query: 421 LLRADIGAASLSLFGDPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSV 480
LLRADIGAASLSLFGDPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSV
Sbjct: 421 LLRADIGAASLSLFGDPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSV 480
Query: 481 GLSRRRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSF 540
GLSRRRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSF
Sbjct: 481 GLSRRRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSF 540
Query: 541 QRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPARTAGAPVR 600
QRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPARTAGAPVR
Sbjct: 541 QRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPARTAGAPVR 600
Query: 601 LDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSV 660
LDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSV
Sbjct: 601 LDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSV 660
Query: 661 VPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTG 720
VPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTG
Sbjct: 661 VPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTG 720
Query: 721 QPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINI 780
QPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINI
Sbjct: 721 QPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINI 780
Query: 781 PGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSS 840
PGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSS
Sbjct: 781 PGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSS 840
Query: 841 APGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSA 900
APGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSA
Sbjct: 841 APGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSA 900
Query: 901 MSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVT 960
MSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVT
Sbjct: 901 MSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVT 960
Query: 961 CVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGT 1020
CVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGT
Sbjct: 961 CVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGT 1020
Query: 1021 RSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGP 1080
RSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGP
Sbjct: 1021 RSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGP 1080
Query: 1081 WGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRER 1140
WGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRER
Sbjct: 1081 WGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRER 1140
Query: 1141 SHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREA 1200
SHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREA
Sbjct: 1141 SHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREA 1200
Query: 1201 SPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVAAECEPDDLDLDY 1260
SPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVAAECEPDDLDLDY
Sbjct: 1201 SPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVAAECEPDDLDLDY 1260
Query: 1261 GDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQR 1320
GDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQR
Sbjct: 1261 GDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQR 1320
Query: 1321 EVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEA 1380
EVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEA
Sbjct: 1321 EVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEA 1380
Query: 1381 ARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMEDV 1440
ARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMEDV
Sbjct: 1381 ARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMEDV 1440
Query: 1441 APTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQF 1500
APTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQF
Sbjct: 1441 APTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQF 1500
Query: 1501 ILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSEEKTPAPRLAAEKTKKEEYM 1560
ILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSEEKTPAPRLAAEKTKKEEYM
Sbjct: 1501 ILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSEEKTPAPRLAAEKTKKEEYM 1560
Query: 1561 KKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVK 1620
KKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVK
Sbjct: 1561 KKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVANLVK 1620
Query: 1621 AYVDKYRHMRRHKKPEAGEEPPTQGAEG 1648
AYVDKYRHMRRHKKPEAGEEPPTQGAEG
Sbjct: 1621 AYVDKYRHMRRHKKPEAGEEPPTQGAEG 1648
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 176 bits (445), Expect = 2e-43
Identities = 229/836 (27%), Positives = 315/836 (37%), Gaps = 143/836 (17%)
Query: 893 PPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEE--------- 943
PP S + R A E AS + +P P+P PWD +
Sbjct: 513 PPTRKKSRRERKRSGEAKEAASSSSGTQPAP----------PAPASPWDSKKHRSRDRKP 562
Query: 944 -DGASCSTFFGSEERTVTCVTVVEPEAPP--------SPDVLQAATHRVVELRPPSRSRS 994
AS S S R+ + T + S + R PP+ S S
Sbjct: 563 GSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSS 622
Query: 995 TSSSRSRKKAK---------RKRVSREHGRTRSGTRSESRDRSSR--SASPSVGEERPRR 1043
+SS R R + K +K+ SR G RSG SE + S S S G+ RR
Sbjct: 623 SSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRR 682
Query: 1044 QRSKAKSRRSSSDRSS-SRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEH 1102
+ + S + +D + +R DKS P S S G S E
Sbjct: 683 RGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEER 742
Query: 1103 YESRKKKKRRSASRPRGRECSPTSSLERLCRHK------HQRERSHERP-DRKESVAWPR 1155
+K RR + G S +SS E+ R K R+R +R DR A P
Sbjct: 743 GGKSSQKDRRRS----GAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPP 798
Query: 1156 DRRKRRSRSP-----------SSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAP 1204
S P SS + R+ + + K ++A+ A
Sbjct: 799 KESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAG 858
Query: 1205 LAQ-GEPGREDLPTRLPALGEAHVSP-EVATAD-----------KAPLQAPPVLEVAAEC 1251
L G D +R P L +P E+A A KA A +
Sbjct: 859 LGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKT 918
Query: 1252 EPDDLDLDY---------GDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPEST----DSSP 1298
+P G V D S A + + +S E + P
Sbjct: 919 KPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPP 978
Query: 1299 ERDFPLKPALPPASLAVAAIQR--EVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEA 1356
+ P PAL P S V + + EVS + +E + +E + E+ E
Sbjct: 979 PKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEE 1038
Query: 1357 PSSP------DVAPAGKEDSPSASGRVQEAAR---PEEVVSQTPLLRSRALVKRVTWNLQ 1407
P A A +PSA ++ P VSQ P L + WNL
Sbjct: 1039 EQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLP-----TLPPPMPWNLP 1093
Query: 1408 ESESSAPAEDRAPRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDT 1467
+ A A L + ++ + Q+ S PS + P T
Sbjct: 1094 AGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKPPSSLGMTPAPVPT 1153
Query: 1468 DPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPA 1527
S GLPP P+ ++L GSLPL GCG+ P P L
Sbjct: 1154 ------SLGLPPGPSS----------------YLLPGSLPLGGCGSTP---PTPTGLAAT 1188
Query: 1528 SEPASQATAASNSEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVT 1587
S+ + +S+SE + ++Y+KKLH QERAVEEVKLAIKP+YQK+++T
Sbjct: 1189 SD---KREGSSSSEGRGDT----------DKYLKKLHTQERAVEEVKLAIKPYYQKKDIT 1235
Query: 1588 KEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRH-KKPEAGEEPP 1642
KEEYKDILRKAV KICHSKSGEINPVKV+NLV+AYV +YR+ R+H +KP PP
Sbjct: 1236 KEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPP 1291
Score = 72.0 bits (175), Expect = 4e-12
Identities = 124/550 (22%), Positives = 193/550 (35%), Gaps = 93/550 (16%)
Query: 701 QSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGSLAP 760
QS C LT G G P S +SS P + S PP P AP
Sbjct: 163 QSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSS--SSPSPPPPPPPPAPPAP 220
Query: 761 LGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPV------------------ 802
P F+ + P + A+S + + F P
Sbjct: 221 PAPR--------FDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEE 272
Query: 803 ------DDKEQRKENPSPLFSIKKTKQLRSEVYDPS----DPTGSDSSAPGSSPERSGPG 852
+++E +E SI + + + +YD + D G +S P + P + P
Sbjct: 273 EEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPA 332
Query: 853 L-LPSEITRTISINSPKAQT----VQAVRC---VTSYTVESIFGTEPEPPLGPSSAMSKL 904
P ++ T + + + + +A C S V + G PPL P
Sbjct: 333 PGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIE 392
Query: 905 RGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTV 964
G + +P E LA L RP G + + T T +
Sbjct: 393 EGEIV----------QPEEEPRLALSLFRP----------GGRAARPTPAASATPTAQPL 432
Query: 965 VEPEAPPSPD-----VLQAATHRV----VELRPPSRSRSTSSSRSRKKAKRKRVSREHGR 1015
+P AP +P+ L A + V+L P+ + + SR R+++ + R
Sbjct: 433 PQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQR-R 491
Query: 1016 TRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSRE 1075
R RS S + + +P+ P R++S+ + +RS ++E A +
Sbjct: 492 ERYRQRSPS---PAPAPAPAAAAGPPTRKKSRRERKRSGE----AKEAASSSSGTQPAPP 544
Query: 1076 HRRGPWGHSRRTSRSRS-GSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRH 1134
PW + SR R GS SSS +RRS SR R R S R
Sbjct: 545 APASPWDSKKHRSRDRKPGSHASSS---------ARRRSRSRSRSRSTRRRSRSTDRRRG 595
Query: 1135 KHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERK 1194
+R RS E+ R+ A P S S HR + S++K ++RS +R
Sbjct: 596 GSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRS 655
Query: 1195 GAVREASPAP 1204
G E +PAP
Sbjct: 656 GDGSEKAPAP 665
Score = 44.3 bits (103), Expect = 0.001
Identities = 77/322 (23%), Positives = 110/322 (34%), Gaps = 63/322 (19%)
Query: 1286 SSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREV-SLMHDEDPS-QPPPLPEGTQEP 1343
SS PSP + SSP P P PPA A A + ++ H D + PPP PE +P
Sbjct: 194 SSSPSPSPSSSSPS---PPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDP 250
Query: 1344 HLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVT 1403
P + + + +P +P +E+ +E EE +SQ+ S L
Sbjct: 251 --FEPTGSNPSSSAGTP--SPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYD 306
Query: 1404 WNLQESE---SSAPAEDRAPRAPLHRPQKP--------------------------REGA 1434
N + +P D P P P P REG
Sbjct: 307 DNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGK 366
Query: 1435 WDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIPPCALVS 1494
+E V G P +LP PG + + ++ P P A S P +
Sbjct: 367 VSVEVVTAGGA-------ALPPPLLP-PGDSEIEEGEIVQPEEEPRLAL-SLFRPGGRAA 417
Query: 1495 QPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSE--------EKTPA 1546
+PT + P AQ L PA P + A S+ E E PA
Sbjct: 418 RPTP---AASATP-----TAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPA 469
Query: 1547 PRLAAEKTKKEEYMKKLHMQER 1568
P A + + +K+ Q R
Sbjct: 470 PPAADSRWGGLDLRRKILTQRR 491
Score = 41.6 bits (96), Expect = 0.006
Identities = 168/861 (19%), Positives = 281/861 (32%), Gaps = 157/861 (18%)
Query: 232 APGVVLAADAGPVSEEEVSLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATVNRNRI 291
AP AA AGP + ++ + R R R+G + A + + +
Sbjct: 502 APAPAPAAAAGPPTRKK-----------SRRERKRSGEAKEAASSSSGTQPAPPAPASPW 550
Query: 292 STA--RRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPG 349
+ R PG SS + + ST R R R+ ++R +++
Sbjct: 551 DSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRR--R 608
Query: 350 RKKTPSGPSAKSKSSATRSKKRQHRVKKRRG---KKVKSEATTRSRIARTLGLRRPV--- 403
R+++ S P A S SS+ S++ +HR K R G KK K + +R G +
Sbjct: 609 RRRSASPPPATSSSSS--SRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPA 666
Query: 404 -----HSSC-----------IPSVLKPVEPSLGLLRADIGAASLSLFGDPYELDP----- 442
+SC PS+ + L ++ I L DP P
Sbjct: 667 PPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDK-SDPRGPSPAPASS 725
Query: 443 ------FDSEELSANPLSPLSAKR-----RALSRSALQSHQPVARPVSVGLSRRR----- 486
+DSE LS S+++ A S S+ + R G R R
Sbjct: 726 PKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRD 785
Query: 487 ----------------LPAAVPEPDLEEEPVPDLLGSILSGQSL----LMLGSSDVIIHR 526
P++ P P + PV GS S S + L S ++ R
Sbjct: 786 RDRDRSSKKARPPKESAPSSGPPP---KPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIR 842
Query: 527 DGSLS---AKRAAPVSFQRNSGSLSRGEEGFKGCLQP-RALPSGSPAQGPSGNRPQSTGL 582
+G S AK AA SR E L+P P+ P +P+ T +
Sbjct: 843 EGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKV 902
Query: 583 SCQGRSRTPARTAG--APVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLP 640
+ ++ T G P + G + S+ + GT
Sbjct: 903 KAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEET 962
Query: 641 LASAASKISSRDSKPPCRSVVPGPPLKPAPRRTDIS----ELPRIPKIRRDDGGGRRDAA 696
S + + S PP ++ P P L P + D S E+ +P+ ++ G R A
Sbjct: 963 SWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAE 1022
Query: 697 PAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEAS--SRVPREPGVHTGSSRPPAPSS 754
+ E E QP T + A+ S P S P+S
Sbjct: 1023 EEEEEEEE------EEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAS 1076
Query: 755 HGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSP 814
S P P +P N+ ++ G + E+ N +
Sbjct: 1077 RVSQLPTLPP--------------PMPWNLPAGVDCTTSGVLALTALLFKMEE--ANLAS 1120
Query: 815 LFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQA 874
++ Q +++ P S P +P + GL P + + + P
Sbjct: 1121 RAKAQELIQATNQILSHRKPPSSLGMTP--APVPTSLGLPPGPSSYLLPGSLPLGGC--- 1175
Query: 875 VRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRP 934
G+ P P G ++ K G+ ++EG DT++ L++
Sbjct: 1176 -------------GSTPPTPTGLAATSDKREGSSSSEGRGDTDK-----------YLKKL 1211
Query: 935 SPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRS 994
E EE + ++ ++ T D+L+ A H++ + +
Sbjct: 1212 HTQERAVEEVKLAIKPYYQKKDIT----------KEEYKDILRKAVHKICHSKSGEINPV 1261
Query: 995 TSSSRSRKKAKRKRVSREHGR 1015
S+ R +R R R+HGR
Sbjct: 1262 KVSNLVRAYVQRYRYFRKHGR 1282
Score = 33.9 bits (76), Expect = 1.3
Identities = 43/199 (21%), Positives = 57/199 (28%), Gaps = 55/199 (27%)
Query: 1288 PPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLR 1347
PP+P S SSP PP P PPP P P
Sbjct: 187 PPAPSSASSSPSPSPSSSSPSPP-------------------PPPPPPAPPAPPAPRFDI 227
Query: 1348 PDAAEKAEAPSSPDVAPAGKED-------SPSASGRVQEAARPEEVVSQTPLLRSRALVK 1400
D + SP AP K D +PS+S EE +
Sbjct: 228 YDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEE----------- 276
Query: 1401 RVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLP 1460
+E E E+ + R + G +D ++ FP P
Sbjct: 277 ------EEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQ----------DFPGDESP 320
Query: 1461 EPGFPDTDPSQVYSPGLPP 1479
P T P+ +PG PP
Sbjct: 321 RPDAQPTQPTP--APGTPP 337
>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
protein [Homo sapiens]
Length = 1463
Score = 128 bits (321), Expect = 5e-29
Identities = 85/222 (38%), Positives = 111/222 (50%), Gaps = 17/222 (7%)
Query: 1420 PRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPP 1479
P+ PLH G M+ PT V Q LP P P QV P
Sbjct: 1251 PQLPLHL----HTGVPLMQVATPTSVSQG----------LPPPPPPPPPSQQVNYIASQP 1296
Query: 1480 APAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASN 1539
Q IP + VS +L G P + +S + A
Sbjct: 1297 DGKQLQGIPSSSHVSNNMSTPVLPAPTAAPG-NTGMVQGPSSGNTSSSSHSKASNAAVKL 1355
Query: 1540 SEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAV 1599
+E K A+ + K + KKL +QE+A +EVKLAIKPFYQ +++TKEEYK+I+RKAV
Sbjct: 1356 AESKVSVAVEASADSSKTD--KKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAV 1413
Query: 1600 QKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKPEAGEEP 1641
K+CHSKSGE+N KVANLVKAYVDKY++ R+ + + EEP
Sbjct: 1414 DKVCHSKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEP 1455
Score = 68.2 bits (165), Expect = 6e-11
Identities = 26/82 (31%), Positives = 50/82 (60%)
Query: 104 DAESCPICLNAFRDQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGG 163
+A+ CPICLN ++ VG PE+C H FC+ CI++W++ SCP+DR F+ + + G
Sbjct: 37 EADRCPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEG 96
Query: 164 KILRKIPVENTKASEEEEDPTF 185
+ ++ + + +++ + +F
Sbjct: 97 YVKVQVKKQLRETKDKKNENSF 118
Score = 62.4 bits (150), Expect = 4e-09
Identities = 97/425 (22%), Positives = 159/425 (37%), Gaps = 47/425 (11%)
Query: 779 NIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSD 838
+ P + S++ P C P+ D + E S + K T+ E+ + D T
Sbjct: 549 DFPTCLTSESKVYQPVSC----PLSDLSENVE--SVVNEEKITESSLVEITEHKDFTLKT 602
Query: 839 SSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESI-----FGTEPEP 893
S S G EI +T+ S K+ VQ + V + VE I FG E
Sbjct: 603 EELIESPKLESSEG----EIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFN 658
Query: 894 PLGPSS--------AMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDG 945
+ S +KL ++ + S TE TE + E +E
Sbjct: 659 NIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIP 718
Query: 946 ASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAK 1005
C +F + + E E + D+ Q + V S + SS + +K +
Sbjct: 719 MECDSFCSDQNES-------EVEPSVNADLKQMNENSVTHC---SENNMPSSDLADEKVE 768
Query: 1006 RKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAK 1065
E + + R R SR SPS + + K +S S R + + ++
Sbjct: 769 TVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESR 828
Query: 1066 RKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPT 1125
+ ++ E RG R+ SRS+S + R++ + RS R RE +
Sbjct: 829 KSQSPSPKNESARG-----RKKSRSQSPKKDIA-----RERRQSQSRSPKRDTTRESRRS 878
Query: 1126 SSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQ 1185
SL R + RE +P K+S P ++ + +SR S+ + R R KW +
Sbjct: 879 ESLSP--RRETSRENKRSQPRVKDSS--PGEKSRSQSRERESDRDGQRRERERRTRKWSR 934
Query: 1186 TRSHS 1190
+RSHS
Sbjct: 935 SRSHS 939
Score = 58.9 bits (141), Expect = 4e-08
Identities = 55/231 (23%), Positives = 96/231 (41%), Gaps = 22/231 (9%)
Query: 971 PSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSR 1030
PSP A + + P + + +S+ ++ ++ +RE R+ S + R ++
Sbjct: 833 PSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENK 892
Query: 1031 SASPSVGEERPRRQRSKAKSRRSSSDRSSSR-ERAKRKKAKDKSREHRRGPWGHSRRTSR 1089
+ P V + P ++S+++SR SDR R ER +R + +SR H R P SR ++
Sbjct: 893 RSQPRVKDSSPG-EKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSP---SRCRTK 948
Query: 1090 SRSGSPGSSSYEHYESRKKKK------RRSASRPRGRECSPTSSLERLCRHKHQRERSHE 1143
S+S S G + Y R K + R R R+ P E + K+ +
Sbjct: 949 SKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDAD 1008
Query: 1144 RPD-----RKESVAWPRDRRKR----RSRSPS--SEHRAREHRRPRSREKW 1183
P+ R + W ++ R+R+P E E+R S W
Sbjct: 1009 DPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSW 1059
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 103 bits (258), Expect = 1e-21
Identities = 281/1182 (23%), Positives = 421/1182 (35%), Gaps = 179/1182 (15%)
Query: 449 SANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDLLGSI 508
S++ LSP A+ ++ + S+Q ++ PV + R P+ + D L
Sbjct: 1382 SSSELSP-----DAVEKAGMSSNQSISSPVLDAVPRT--PSRERSSSASSPEMKDGLPRT 1434
Query: 509 LSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNSGSL----SRGEEGFKGCLQPRALP 564
S +S GSS + RDGS + R + + SRG +P+ALP
Sbjct: 1435 PSRRS--RSGSSPGL--RDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490
Query: 565 ------SGSPAQGPSGNR---PQS--TGLSCQGRSRTPART-------AGAPVRLDLPAA 606
S SP+ N+ PQ +G +T ART +G+ LD+ +
Sbjct: 1491 QTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPS 1550
Query: 607 PGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSVVPGPPL 666
+ Q R+ S+ S ++ +P + + P + S++S R S+ V P
Sbjct: 1551 -ASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP- 1608
Query: 667 KPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGT 726
+ APR S+ PK APA P A R R G+ GRG
Sbjct: 1609 RAAPRAQSGSDSSPEPK------------APA-------PRALPRR--SRSGSSSKGRGP 1647
Query: 727 RAESEASSRV-----PREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIP 781
E +S+ P+ GS P P + P R + S+ E R
Sbjct: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP----RRRSSRSSPELTRKARL 1703
Query: 782 GNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSA 841
+ S+ SSP + P + +P P + +++ RS S P +S
Sbjct: 1704 SRRSRSAS-SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA----SSPRTKTTSR 1758
Query: 842 PGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAM 901
G SP GL S R+ S T + R +S + + S
Sbjct: 1759 RGRSPSPKPRGLQRS---RSRSRREKTRTTRRRDRSGSSQSTSR----RRQRSRSRSRVT 1811
Query: 902 SKLRGAVAAEGASDTEREEP-TESQGLAARLRRP----------SPPEPWDEEDG-ASCS 949
+ RG S +E T S+ R R P + P PW AS +
Sbjct: 1812 RRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871
Query: 950 TFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRV 1009
T S RT ++ + SP + + R R SRSR++ SR R +++ V
Sbjct: 1872 THRRSRSRT-PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPV 1930
Query: 1010 SREHGRTRSGT---RSESRD-----RSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSR 1061
+R R+R+ T RS SR R SRS +P V R R + S RRS S S
Sbjct: 1931 TRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVT 1990
Query: 1062 ERAKRKKAKDKSREHRRGPWGH-SRRTSRSRSGSP---GSSSYEHYESRKKKKRRS--AS 1115
R R + +R R +RR SRSR+ S S RK+ + RS A
Sbjct: 1991 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAI 2050
Query: 1116 RPRGRECSPTS-----SLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPS---S 1167
R R R +P + SL R +R S DR S P R SR+P +
Sbjct: 2051 RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN 2110
Query: 1168 EHRAREHRRPRSREKWPQTRSHSP---ERKGAVREASPAPLAQGEPGREDLPTRLP---- 1220
R RP S P R SP E G+ R G + R+P
Sbjct: 2111 SSRMSCFSRP-SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQR 2169
Query: 1221 -ALGEAHVSPEVATADKA----PLQAPPVLEVAAECE-----PDDLDLDYGDSVEAGHVF 1270
++ E H +A A A + PP + A P + L + A ++
Sbjct: 2170 TSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLA 2229
Query: 1271 DDF-SSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDED 1329
++ A + L +P P + + + R A+ AS A V+L
Sbjct: 2230 SRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRT 2289
Query: 1330 PSQPPPLPEGTQEPHLLR----------------PDAAEKAEAPSSPDVAPAGKEDSPS- 1372
P+ P G + P L P ++ +AP+S ++ + +
Sbjct: 2290 PTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAP 2349
Query: 1373 ---ASGRVQEAARPEEVVS--QTPLLRSRALVK-RVTWNLQESESSAPAEDRAPRAPLHR 1426
A R A P + S P L L RV + E S + RA
Sbjct: 2350 VNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRT 2409
Query: 1427 PQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAPAQPSS 1486
P AP+ R P PS + + PSQ LPPA QP S
Sbjct: 2410 PPS-----------APSQSRMTSERAPSPSSRMGQA------PSQSL---LPPAQDQPRS 2449
Query: 1487 IPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPAS 1528
P A Q + ++ + P+ G +Q+L+ A T +S
Sbjct: 2450 PVPSAFSDQS--RCLIAQTTPVAG---SQSLSSGAVATTTSS 2486
Score = 95.5 bits (236), Expect = 4e-19
Identities = 166/643 (25%), Positives = 239/643 (37%), Gaps = 88/643 (13%)
Query: 636 KHTLPLASAASKISSRDSKPP-CRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRD 694
KH P + SK S+D K RS P P + A R T R R
Sbjct: 228 KHRSP--TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR---SRSRSA 282
Query: 695 AAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTGSSRPPAPSS 754
AA H + L GR + P G R E +A EPG T + RP +P +
Sbjct: 283 AAKTH----------TTALAGRSPS--PASGRRGEGDAPFS---EPGT-TSTQRPSSPET 326
Query: 755 HGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSP 814
+ P P K +S P S+ P E+ +P P
Sbjct: 327 -ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA-----ERHGGSPQP 380
Query: 815 LFSIKKTKQL------RSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISIN--S 866
L + +++ S D S P + SS E S P P++++R S + S
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 867 PKAQTVQAVRCVTSYTVESIFGTEPEPPLG------PSSAMSKLRGAVAAEGASDTEREE 920
PK S + S + PS M + R A+ R
Sbjct: 441 PKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT- 499
Query: 921 PTE---SQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQ 977
PT+ S+ + + RR + W S +R + S +
Sbjct: 500 PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARR 559
Query: 978 AATH-RVVELRPPSRSRSTSS---SRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSAS 1033
+H R R SRSR+ + SRSR A+R+ SR R RS +R+ +R SRS +
Sbjct: 560 GRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619
Query: 1034 PSVGEERPR-----RQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTS 1088
P+ R R R RS++ +RRS RS + R R +++ +R R +RR+
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSG 679
Query: 1089 RSRSGSPGSSSYEHYESRKKKKRRSASRP---RGRECSPT--------SSLER--LCRHK 1135
RSRS +P SR ++ RS SR RGR S T SS ER R
Sbjct: 680 RSRSRTPARRG--RSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737
Query: 1136 HQRERSHERPD---------RKESVAWPRDRRK-----RRSRSPSS----EHRAREHRRP 1177
+R RS+ P+ R S++ PR + K RRS S SS + RR
Sbjct: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797
Query: 1178 RSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLP 1220
RS P+ +S +P R+ + P P R+ + P
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Score = 92.4 bits (228), Expect = 3e-18
Identities = 303/1226 (24%), Positives = 438/1226 (35%), Gaps = 229/1226 (18%)
Query: 445 SEELSANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDL 504
SEE + LS LS++ + +S S +S V +V L+ L + + LE VP +
Sbjct: 1245 SEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT---LDQSQSQASLEAVEVPSM 1301
Query: 505 L---GSILSGQSLLMLGSSDVIIHRDGS-LSAKRAAPVSFQRNSGSLSRGEEGFKGCL-- 558
G L +S + + GS L + + P+ + N+G S +E G
Sbjct: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361
Query: 559 -----------QPRALPSGSPAQGPSGNRPQSTGLSCQGR---------SRTPAR----T 594
+ SG + S + + G+S RTP+R +
Sbjct: 1362 QLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSS 1421
Query: 595 AGAPVRLD-LPAAPGAVQARNLSNGSVPGFRQSHSPWFNGT-NKHTLPLASAASKISSR- 651
A +P D LP P +R +GS PG R +GT ++H+L +S K R
Sbjct: 1422 ASSPEMKDGLPRTP----SRRSRSGSSPGLRDG-----SGTPSRHSLSGSSPGMKDIPRT 1472
Query: 652 --------DSKPPCRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSI 703
DS P +++ P P PR S P P++ +R+ + G
Sbjct: 1473 PSRGRSECDSSPEPKAL----PQTPRPR----SRSPSSPELNNKCLTPQRERS---GSES 1521
Query: 704 EIPSACISRLT----GREGTGQ-----PGRGTRAESEASS--------RVPREPGVHTGS 746
+ ++R R G+ Q P + SE+ S R P +GS
Sbjct: 1522 SVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGS 1581
Query: 747 SRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKE 806
S P S L+P R GS+ E A S SSP
Sbjct: 1582 S--PEVDSKSRLSP----RRSRSGSSPEVKDKPRAAPRAQSGSDSSP------------- 1622
Query: 807 QRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISINS 866
+ P+P ++++ S P GS S+ SSPE S R S +S
Sbjct: 1623 -EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE--SSPEHPPK----SRTARRGSRSS 1675
Query: 867 PKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQG 926
P+ +T S T + P L + +S R + +A + +T P +
Sbjct: 1676 PEPKT-------KSRTPPRRRSSRSSPELTRKARLS--RRSRSASSSPETRSRTPPRHR- 1725
Query: 927 LAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAP-PSPDVLQAATHRV-- 983
R S PEP E+ +S S RT T T +P P P LQ + R
Sbjct: 1726 ---RSPSVSSPEP-AEKSRSSRRRRSASSPRTKT--TSRRGRSPSPKPRGLQRSRSRSRR 1779
Query: 984 VELRPPSR------SRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVG 1037
+ R R S+STS R R +++ + R G + +RS +R SSR++S
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS---- 1835
Query: 1038 EERPRRQRSKA--KSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGH---SRRTSRSRS 1092
R RR RS+ SR+ S R+S KR +++ HRR SRR SRSR+
Sbjct: 1836 --RRRRGRSRTPPTSRKRSRSRTSPAP-WKRSRSRASPATHRRSRSRTPLISRRRSRSRT 1892
Query: 1093 G------SPGSSSYEHYESRKK----KKRRSASR----PRGRECSPTSSLERLCRHK--- 1135
S +S SR + +RRS SR R R S T + R R +
Sbjct: 1893 SPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPP 1952
Query: 1136 --HQRERSHERP---DRKESVAWPRDRRKRRSR-SPSSEHRARE------HRRPRSREKW 1183
+R RS P R S P RR+ RSR SP + R+R RR RSR
Sbjct: 1953 VTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTS- 2011
Query: 1184 PQTRSHSPERKGAV---REASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQ 1240
P TR S R R S PL + R P + + +P A ++ +
Sbjct: 2012 PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSR-TPRTARGKRSLTR 2070
Query: 1241 APPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDM------SSPPSPEST 1294
+PP + D + A + V + M S P+P
Sbjct: 2071 SPPAIR-RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDR 2129
Query: 1295 DSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKA 1354
SP PL + P S+ Q S+M P P E H + A
Sbjct: 2130 CRSPGMLEPLGSSRTPMSVLQ---QAGGSMMDGPGPRIPDHQRTSVPENHA----QSRIA 2182
Query: 1355 EAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESSAP 1414
A ++ + A S SA+G AAR +V + PL+ R +AP
Sbjct: 2183 LALTAISLGTARPPPSMSAAGL---AARMSQVPAPVPLMSLR---------------TAP 2224
Query: 1415 AEDRAPRAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDT--DPSQV 1472
A + A R P A PT V S P + + P T PS V
Sbjct: 2225 AANLASRIPA-ASAAAMNLASARTPAIPTAVNLADSRTPAAAAAM-NLASPRTAVAPSAV 2282
Query: 1473 --YSPGLPPAPA--QPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPAS 1528
P P APA + P AL +L L G G T A P++
Sbjct: 2283 NLADPRTPTAPAVNLAGARTPAAL-----------AALSLTGSGTPPTAANYPSSSRTPQ 2331
Query: 1529 EPASQATAASNSEEKTPAPRLAAEKT 1554
PAS S T +A +T
Sbjct: 2332 APASANLVGPRSAHATAPVNIAGSRT 2357
Score = 87.0 bits (214), Expect = 1e-16
Identities = 227/1027 (22%), Positives = 362/1027 (35%), Gaps = 179/1027 (17%)
Query: 260 TSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDE-------- 311
T+R R R+G +++ +R RQ R R+ V R R + +P R SS
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
Query: 312 ----AIEAVATGLSTAVYQRPLTPRTPARRKRKTRR-----RKKVPGRKKTPSGPSAKSK 362
+ + + S A ++R + +PA +R R R++ R S ++S+
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
Query: 363 SSATR--SKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVE---P 417
+S TR S+ R V +RR + T R +RT RR S P + P
Sbjct: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
Query: 418 SLGLLRADIGAASLSLFGDPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVARP 477
+ R+ + ++ P + S + SP++ +RR+ SR++ P
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPV-TRRRSRSRTSPVT-RRRSRSRTS---------P 2012
Query: 478 VSVGLSRRRLPAAVPEPDLEEEPV-PDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAA 536
V+ SR R P A+ P+ P S ++ S G S R+
Sbjct: 2013 VTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP 2072
Query: 537 PVSFQRNSGSLSRGEEGFKGCLQPRALPSGSPA-QGPSGNRPQSTGLSCQGRSRTPARTA 595
P + +R S S G R+ + PA + SG+R L+ R +R +
Sbjct: 2073 P-AIRRRSAS---------GSSSDRSRSATPPATRNHSGSRTPPVALN-SSRMSCFSRPS 2121
Query: 596 GAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTN-------KHTLP-------L 641
+P LD +PG ++ S + +Q+ +G + ++P +
Sbjct: 2122 MSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRI 2181
Query: 642 ASAASKISSRDSKPPCR----------SVVPGP----PLKPAPRRTDISELPRIPKIRRD 687
A A + IS ++PP S VP P L+ AP S +P +
Sbjct: 2182 ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMN 2241
Query: 688 DGGGRRDAAPAH---GQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVH- 743
R A P S +A L P A + A R P P V+
Sbjct: 2242 LASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPS----AVNLADPRTPTAPAVNL 2297
Query: 744 --------------TGSSRPPAPSSH--GSLAPLGPSRGKGVG--STFESFRINIPGNMA 785
TGS PP +++ S P P+ VG S + +NI G+
Sbjct: 2298 AGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRT 2357
Query: 786 HSS------------------QLSSPGFC---------NTFRPVDDKEQRKENPSPLFSI 818
++ L+SP T P+ D+ + + PS
Sbjct: 2358 AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
Query: 819 KKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSE--------ITRTISINSPKAQ 870
+ T + S S P + + P +PS I +T + ++
Sbjct: 2418 RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP--VPSAFSDQSRCLIAQTTPVAGSQSL 2475
Query: 871 TVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAAR 930
+ AV TS + P P S + + + A+ S +P + + ++
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS 2535
Query: 931 LRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAP----PSPDVLQAATHRVVEL 986
S +S S+ S + V+PE PSP A V E
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT--PAPKEAVREG 2593
Query: 987 RPPS--------RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGE 1038
RPP RS S+SSS S + S + S + S S SS S+SPS
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS--- 2650
Query: 1039 ERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSS 1098
P + +A + +S + ER R K S R SRS S SP
Sbjct: 2651 --PAKPGPQALPKPASPKKPPPGERRSRSPRKPID----------SLRDSRSLSYSP--- 2695
Query: 1099 SYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRR 1158
++RR + +P R+ +SS R + RS R+E+ + PR R
Sbjct: 2696 ---------VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS-PRPMR 2745
Query: 1159 KRRSRSP 1165
R SRSP
Sbjct: 2746 HRSSRSP 2752
Score = 75.9 bits (185), Expect = 3e-13
Identities = 266/1264 (21%), Positives = 420/1264 (33%), Gaps = 205/1264 (16%)
Query: 261 SRLRPRAGRTRAIARTRQSERVRATVNRNRIS------TARRVQHTPGRLGSSLL-DEAI 313
SR R GR+R+ R+ R R+ V R S + R TP R G S A
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
Query: 314 EAVATGLSTAVYQRPLTPRTPARRKR---KTRRRKKVPGRKKTPSG------PSAKSKSS 364
+ + A RTPARR R +T RR + R G P + +S
Sbjct: 666 RGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725
Query: 365 ATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRA 424
++ +K + R +RR + S +SRI+ S + S + L L R+
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSR-------RSRSLSSPRSKAKSRLSLRRS 778
Query: 425 DIGAASLSLFGDPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSR 484
G++ + P S S+ P AK R R + S P + S SR
Sbjct: 779 LSGSSPCP--KQKSQTPPRRSRSGSSQP----KAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
Query: 485 RRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNS 544
+ ++ P P + + P GSI S Q+ V R + + + S
Sbjct: 833 QSHSSSSPHPKV-KSGTPPRQGSITSPQA----NEQSVTPQRRSCFESSPDPELKSRTPS 887
Query: 545 GSLSRGEE--GFKGCLQPRALPSGSPAQGP------SGNRPQSTGLSCQGRSRTPARTAG 596
G K PR PS S + P S + +G S SR +RT
Sbjct: 888 RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947
Query: 597 APVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNK---HTLPLASAASKISSRDS 653
R P + N+ + +P R SHS + K T P S + IS
Sbjct: 948 RRSRSVSPCS-------NVESRLLP--RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPK 998
Query: 654 KPPCRSVVPGPPL----KPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSAC 709
PGP L P P+ L + G + + P + S
Sbjct: 999 VK--AQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSL- 1055
Query: 710 ISRLTGREGTGQPGRGTRAESEASSRVPREPGVHT--------GSSRPPAPSSH-GSLAP 760
+L G+ T R + E P + + G SR +P + S +P
Sbjct: 1056 --QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
Query: 761 LGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKK 820
+ RG+ F + + G S+ S +++ VD ++ K+
Sbjct: 1114 IRQDRGE-----FSASPMLKSGMSPEQSRFQSDS--SSYPTVDSNSLLGQSRLETAESKE 1166
Query: 821 TKQL-RSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTI------SINSPKAQTVQ 873
L E S P D +P +R L+ + RT + +SP+ +
Sbjct: 1167 KMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQN 1226
Query: 874 AVRCVTSYTVESIFGTE-PEPPLGP--SSAMSKLRGAVAAEGASDTEREE---------P 921
+ +S E + E E P G S S+L+ + S E EE
Sbjct: 1227 SALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQ 1286
Query: 922 TESQGLAARLRRPSPPEPWDEED------------------------------GASCSTF 951
++SQ + PS W G +T
Sbjct: 1287 SQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTG 1346
Query: 952 FGSE-ERTVTCVTVVEPEAPPSPDVLQAAT----HRVVELRPPSRSRS-TSSSRSRKKAK 1005
F SE + + + + E PS D+ + +T H EL P + ++ SS++S
Sbjct: 1347 FSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPV 1406
Query: 1006 RKRVSREHGRTRSGTRSESRDRSSRSASPS----VGEERPRRQRSKAKSRRSSSDRSSSR 1061
V R R RS + S + +PS G R S SR S S S
Sbjct: 1407 LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGM 1466
Query: 1062 ERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRS-------- 1113
+ R ++ +S +T R RS SP S + +++R
Sbjct: 1467 KDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQK 1526
Query: 1114 --ASRPRGRECSPTSSLE---RLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSE 1168
A P G+ SS E + +R S PD K P +R R SP +
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586
Query: 1169 HRAR-EHRRPRSREKWPQTRS--HSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEA 1225
++R RR RS P+ + + R + ++SP P A P LP R + +
Sbjct: 1587 SKSRLSPRRSRSGSS-PEVKDKPRAAPRAQSGSDSSPEPKA---PAPRALPRRSRSGSSS 1642
Query: 1226 H---VSPEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQL 1282
SPE +++ ++ + PP A
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRTARR-------------------------------- 1670
Query: 1283 DDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQE 1342
S P P++ +P R + + P A + R ++ P +
Sbjct: 1671 -GSRSSPEPKTKSRTPPRRRSSRSS--PELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 1343 PHLLRPDAAEK---------AEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLL 1393
P + P+ AEK A +P + + G+ SP G + +R ++T
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 1394 RSRA 1397
R R+
Sbjct: 1788 RDRS 1791
Score = 73.6 bits (179), Expect = 2e-12
Identities = 236/1037 (22%), Positives = 364/1037 (35%), Gaps = 149/1037 (14%)
Query: 259 TTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVAT 318
T SR PR R+ +++ +E+ R++ R S+ R T R G S +
Sbjct: 1716 TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT--KTTSRRGRSPSPK------- 1766
Query: 319 GLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKR 378
PR R + ++RR K R++ SG S + RS+ R ++R
Sbjct: 1767 ------------PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRR 1814
Query: 379 RGKK-VKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEP--SLGLLRADIGAASLSLFG 435
RG S + R +RT RR S P+ K S + AS +
Sbjct: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR 1874
Query: 436 DPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVAR--PVSVGLSRRRLPAAVPE 493
P S S + SP+S +RR+ SR+++ + +R PVS SR R P
Sbjct: 1875 RSRSRTPLISRRRSRSRTSPVS-RRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
Query: 494 PDLEEEPV---------PDLLGSILSGQSLLMLG------SSDVIIHRDGSL-------- 530
P P + ++ + +S + R S
Sbjct: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRR 1993
Query: 531 SAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSC-----Q 585
S R +PV+ +R+ S P A+ S ++ P R +S S +
Sbjct: 1994 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRR 2053
Query: 586 GRSRTPARTAGAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWF-NGTNKHTLPLASA 644
RSRTP G + L +P A++ R+ S S R + P N + T P+A
Sbjct: 2054 SRSRTPRTARG---KRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN 2110
Query: 645 ASKIS--SRDSKPP-----CRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGR----- 692
+S++S SR S P CRS PG RT +S L + D G R
Sbjct: 2111 SSRMSCFSRPSMSPTPLDRCRS--PGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQ 2168
Query: 693 RDAAPA-HGQS-IEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTGSSRPP 750
R + P H QS I + IS T R G A S+VP V S R
Sbjct: 2169 RTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARM---SQVPAP--VPLMSLRTA 2223
Query: 751 APSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKE 810
++ S P + + S + I N+A S ++ N P +
Sbjct: 2224 PAANLASRIPAASAAAMNLASA-RTPAIPTAVNLADSRTPAAAAAMNLASP-----RTAV 2277
Query: 811 NPSPLFSIKKTKQLRSEVYDPSDPT-------GSDSSAPGSSPERSGPGLLPSEITRTIS 863
PS + + DP PT G+ + A ++ +G G P+ S
Sbjct: 2278 APSAV-----------NLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326
Query: 864 INSPKAQT---VQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDT---- 916
+P+A + R + +I G+ L P+S ++ R A A GA+ T
Sbjct: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPAS-LTSARMAPALSGANLTSPRV 2385
Query: 917 -----EREEPTESQGLAARLRRPSPPEPWDE-----EDGASCSTFFG-SEERTVTCVTVV 965
ER S L R R +PP + E S S+ G + +++
Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 966 EPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESR 1025
+P +P + + + P + S+S SS A + +H S
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV---ATTTSSAGDHNGMLSVPAPGVP 2502
Query: 1026 DRSSRSASPSVGEERPRRQRS--KAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGH 1083
S G ++P + AK RRSSS SSS +
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS------------------ 2544
Query: 1084 SRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHE 1143
S +S S S S GSSS + S + A + R SPT + + R E +
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK---RVPSPTPAPKEAVREGRPPEPTPA 2601
Query: 1144 RPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPA 1203
+ R+ S + S S SS + S + S SP +A P
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 1204 PLAQGEPGREDLPTRLP 1220
P + +P + +R P
Sbjct: 2662 PASPKKPPPGERRSRSP 2678
Score = 72.8 bits (177), Expect = 3e-12
Identities = 260/1178 (22%), Positives = 384/1178 (32%), Gaps = 201/1178 (17%)
Query: 327 RPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKS--SATRSKKRQHRVKKRRGK-KV 383
R TP+ ++K+K R R+ + S+K K S + SKKR+HR + K K
Sbjct: 181 RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS 240
Query: 384 KSEATTRSRIARTLGLRRPVHSSCI----------------------PSVLKPVEPSLGL 421
K + RSR R H S + L PS
Sbjct: 241 KDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300
Query: 422 LRADIGAASLSLFG------------------DPYELDPFDSEELSANPLS--------- 454
R G A S G PYE D +E SA S
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 455 -------PLSAKRRALSRSALQ----SHQPVARPVSVGLSRRRLPAAVPE---PDLEEEP 500
PL A+R S L S +PV P +R R P PE E
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
Query: 501 VPDLLGSILSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQP 560
P + S GS ++P S R+ G R ++
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR-DKSHSHTPSR 479
Query: 561 RALPSGSPAQGPSG--------NRPQSTGLSCQ----------GRSRTPARTAGAPVRLD 602
R S SPA G R S S Q GRSR+P R R
Sbjct: 480 RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG----RSR 535
Query: 603 LPAAPGAVQARNL-----SNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPC 657
P PG ++RN S + G S SP G ++ P S+ S ++
Sbjct: 536 SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR-SRTPARRRS 594
Query: 658 RSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIPSACISRLTGRE 717
RS P RR S P R RR + S +R +GR
Sbjct: 595 RSRTP-------TRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS 647
Query: 718 GTGQPGRGTRAESEASSR----VPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTF 773
+ P R R+ S +R R P +G SR P+ G P RG+
Sbjct: 648 RSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR------ 701
Query: 774 ESFRINIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSD 833
R + +HS G + +K + + S S + K+ R
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR-------- 753
Query: 834 PTGSDSSAPGSSPERSGPGLLPSEITRTISINSP----KAQTVQAVRCVTSYTVESIFGT 889
S S SSP L + R++S +SP K+QT S ++ T
Sbjct: 754 -ISSRRSRSLSSPRSKAKSRL--SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 890 EPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCS 949
P SS K + + + + P G R + P+ ++
Sbjct: 811 PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Query: 950 TFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRV 1009
+ F S ++ P ++ RV PP +S S SSS + K K +
Sbjct: 871 SCFESSPD-----PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS---PQPKVKAI 922
Query: 1010 SREHGRTRSGTRSES--------RDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSR 1061
R+ SG+ S S R SRS SP E S+ R S S SS
Sbjct: 923 ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE------SRLLPRYSHSGSSSPD 976
Query: 1062 ERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRS-------- 1113
+ K + +S P+ + + GS S E K +S
Sbjct: 977 TKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLC 1036
Query: 1114 ----ASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEH 1169
+S P G SSL+ + +S PD + + P + R+ S SPS
Sbjct: 1037 AGVKSSTPPGESYFGVSSLQ-------LKGQSQTSPDHRSDTSSP-EVRQSHSESPSL-- 1086
Query: 1170 RAREHRRPRSREKWPQTRSHSPERKGAVREASP-APLAQGEPGREDLPTRLPALGEAHVS 1228
Q++S + + G R +SP LA P R+D GE S
Sbjct: 1087 ---------------QSKSQTSPKGGRSRSSSPVTELASRSPIRQD-------RGEFSAS 1124
Query: 1229 PEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSP 1288
P + + +P Q+ + ++ D L +E + A+ Q D +SP
Sbjct: 1125 P-MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETA---ESKEKMALPPQEDATASP 1180
Query: 1289 PSPESTDSS-PERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLR 1347
P + S P +D P + +L +R + E Q LP +Q+ L+
Sbjct: 1181 PRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM- 1239
Query: 1348 PDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEE 1385
+ EK+E P+ ++ E ++ + + EE
Sbjct: 1240 -EVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEE 1276
Score = 71.2 bits (173), Expect = 8e-12
Identities = 253/1194 (21%), Positives = 403/1194 (33%), Gaps = 182/1194 (15%)
Query: 261 SRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLL-DEAIEAVATG 319
SR R GR+R+ R R R AT R+R TP R G S A +
Sbjct: 545 SRNTQRRGRSRSARRGRSHSRSPATRGRSR-------SRTPARRGRSRSRTPARRRSRSR 597
Query: 320 LSTAVYQRPLTP--------RTPARRKRKTRRRKKVPGRKKTPSGPSAKSKS-SATRSKK 370
T R TP RTPARR+ +TR + R ++P+ S +S+S + R +
Sbjct: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGR 657
Query: 371 RQHRVKKRRGKKVKSEATTRSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRADIGAAS 430
+ R RRG+ RS +R+ R P
Sbjct: 658 SRSRTPARRGRSRSRTPARRSGRSRS---RTPARR------------------------- 689
Query: 431 LSLFGDPYELDPFDSEELSANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAA 490
S P S R + R S P R S S R+ +
Sbjct: 690 --------------GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 491 VPEPDLEEEPVPDLLGSILSGQSLLMLGS------SDVIIHRDGSLSAKRAAPVSFQRNS 544
+ P++ S +S + L S S + + R SLS P +
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR--SLSGSSPCPKQKSQTP 793
Query: 545 GSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPAR---TAGAP--- 598
SR G QP+A P + S + P + +S+TP+R ++ +P
Sbjct: 794 PRRSR-----SGSSQPKAKSRTPPRRSRSSSSPPP-----KQKSKTPSRQSHSSSSPHPK 843
Query: 599 VRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCR 658
V+ P G++ + + SV R+S F + L + + S S P +
Sbjct: 844 VKSGTPPRQGSITSPQANEQSVTPQRRS---CFESSPDPELKSRTPSRHSCSGSSPPRVK 900
Query: 659 SVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAPAHGQSIEIP--SACISRLTGR 716
S P P P+ + ++ I R+ G +P+ S P S +S +
Sbjct: 901 SSTP-PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV 959
Query: 717 EGTGQPGRGTRAESEASSRV-PREP--GVHTGS---------SRPPAPSSHGSLAPLGPS 764
E P S ++V P P H+GS PP PS GS +P
Sbjct: 960 ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
Query: 765 RGKGVGSTFESFRINIPGNMAHSSQLSS---PGFCNTFRPVDD---KEQRKENPSPLFSI 818
+ K +S + PG+++ + + S PG ++ V K Q + +P
Sbjct: 1020 KSK------DSLVQSCPGSLSLCAGVKSSTPPG--ESYFGVSSLQLKGQSQTSPDHRSDT 1071
Query: 819 KKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCV 878
+ +S PS + S +S G S P +E+ I + + +
Sbjct: 1072 SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP---VTELASRSPIRQDRGEFSASPMLK 1128
Query: 879 TSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREE-PTESQGLAARLRRPSPP 937
+ + E + + P+ + L G E A E+ P + A+ R+
Sbjct: 1129 SGMSPEQ-SRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Query: 938 EPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSS 997
P+ +D S F RT PP ++ E + + + TSS
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRT-----------PPRE---RSGAGSSPETKEQNSALPTSS 1233
Query: 998 SRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRS--ASPSVGEERPRRQRSKAKSR-RSS 1054
++ G+ S SE ++ S+ + +SP V EERP + +S+ ++S
Sbjct: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEV-EERPAVSLTLDQSQSQAS 1292
Query: 1055 SDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTS-----RSRSGSPGSSSYEHYESRKKK 1109
+ A S EH+ R S R+ P + S + K
Sbjct: 1293 LEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK 1352
Query: 1110 KRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRD------------R 1157
+ + E P+ ++ S PD E + R
Sbjct: 1353 EDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPR 1412
Query: 1158 RKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAP----LAQGEPGRE 1213
R RS S+ + PR+ P RS S G +R+ S P L+ PG +
Sbjct: 1413 TPSRERSSSASSPEMKDGLPRT----PSRRSRSGSSPG-LRDGSGTPSRHSLSGSSPGMK 1467
Query: 1214 DLPTRLPALG--EAHVSPEVATADKAP---LQAPPVLEVAAEC-----EPDDLDLDYGDS 1263
D+P R P+ G E SPE + P ++P E+ +C E +
Sbjct: 1468 DIP-RTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQK 1526
Query: 1264 VEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVS 1323
A S +LD S E ++S D K P + + EV
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV- 1585
Query: 1324 LMHDEDPSQPPPLPEGTQEPHLL-RPDAAEKAEAPSSPDVAPAGKEDSPSASGR 1376
D P P + +P AA +A+ S D +P K +P A R
Sbjct: 1586 ---DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ--SGSDSSPEPKAPAPRALPR 1634
Score = 68.2 bits (165), Expect = 6e-11
Identities = 103/485 (21%), Positives = 168/485 (34%), Gaps = 74/485 (15%)
Query: 971 PSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSR 1030
P+PD+L R VELR ++ +++V+ + +
Sbjct: 53 PNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETP 112
Query: 1031 SASPSVGEERPRRQRSKAKSRR---------SSSDRSSSRERAKRKKAKDKSREHRRGPW 1081
P+V E + ++ K+ R S D SS + + ++AK + E + P+
Sbjct: 113 GQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPK-PY 171
Query: 1082 GHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERS 1141
R +S SRS +P + +KKKK++ R R SP ++ + K R S
Sbjct: 172 SLVRESSSSRSPTP--------KQKKKKKKKDRGR-RSESSSPRRERKKSSKKKKHRSES 222
Query: 1142 HERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREAS 1201
+ +RK RS +P S+ ++++ +R RSR P +S R + AS
Sbjct: 223 ESK------------KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270
Query: 1202 PAPLAQGEPGREDLPTRLPALGEAHVSPEVATADK--APLQAPPVLEVAAECEPDDLDLD 1259
+ ++ T AL SP + AP P P+
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETA--- 327
Query: 1260 YGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALP------PASL 1313
+ + ++D D + PSPE + + PE P P L P L
Sbjct: 328 ---TKQPSSPYEDKDKDKK--EKSATRPSPSPERSSTGPEPPAPT-PLLAERHGGSPQPL 381
Query: 1314 AVAAIQRE-------VSLMHDEDP---------------SQPPPLPEGTQEPHLLRPDAA 1351
A + +E S D P S P P P P++
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
Query: 1352 EKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESES 1411
+ A AP S SP++ R A+ ++ S TP R T S S
Sbjct: 442 KPAPAPGSHREI----SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRS 497
Query: 1412 SAPAE 1416
P +
Sbjct: 498 RTPTK 502
Score = 67.0 bits (162), Expect = 1e-10
Identities = 229/1107 (20%), Positives = 369/1107 (33%), Gaps = 147/1107 (13%)
Query: 572 PSGNRPQSTGLSCQGRSRTPA---RTAGAPVRLDLPAAPGAVQARNLSNGSVPGFR---- 624
P R + RS TPA R A D ++ ++R+ S +
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
Query: 625 QSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSVVPGPPLKPAPR-RTDISELPRIPK 683
+S SP + P + + + R S P + P P + + + + S P
Sbjct: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
Query: 684 IRRDDGGGRRDA-----APAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPR 738
R G A A HG S P + +E P + + + P
Sbjct: 354 PERSSTGPEPPAPTPLLAERHGGS---PQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
Query: 739 E-PGVHTGSSRPPAP-----SSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHS----- 787
+ P + S PP+P S H S +P P GS E N +H
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD 470
Query: 788 ---SQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGS 844
S S + P K R + +P TK+ S P + G
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRGRSRSRTP------TKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 845 S--PERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMS 902
S P+R G P + S N+ + ++ R S++ S
Sbjct: 525 SRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS 584
Query: 903 KLRGAVAAEGASDTEREEPTESQGLAAR------------------LRRPSPPEPWDEED 944
+ R S T + S+ A R +RR S
Sbjct: 585 RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS 644
Query: 945 GASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQA--ATHRVVELRPPSRSRSTSSSRSRK 1002
G S S R+ + + ++ + R R SRSR+ RSR
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
Query: 1003 KAKRKRVSREHGRT-----RSGTRSE-------SRDRSSRSASPSVGEERPRRQRSKAKS 1050
++ +R R H RT RSG+ SE S+ RS ++SP E + + S +S
Sbjct: 705 RSLVRR-GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP----EMKKSRISSRRS 759
Query: 1051 RRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKK 1110
R SS RS ++ R +++ S + R SRS S P + S ++
Sbjct: 760 RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS-----RTPPRR 814
Query: 1111 RRSASRPRGRECSPTSSLERLCRHKHQRERSHER-----PDRKESVAWPR--------DR 1157
RS+S P ++ S T S R H H + P R+ S+ P+ R
Sbjct: 815 SRSSSSPPPKQKSKTPS-----RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR 869
Query: 1158 RKRRSRSPSSEHRAR-EHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLP 1216
R SP E ++R R S P+ +S +P R+ R +SP P + P
Sbjct: 870 RSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS----P 925
Query: 1217 TRLPALGEAHVSPEVATADKAPLQA---PPVLEVAAECEP-----DDLDLDYGDSVEAGH 1268
+ G + SP T+ P ++ P V + P D E
Sbjct: 926 RQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP 985
Query: 1269 VFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALP---PASLAVAAIQRE---- 1321
S + + ++ + P S SP K +L P SL++ A +
Sbjct: 986 RQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 1322 ------VSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAG---KEDSPS 1372
VS + + SQ P +R +E S +P G + SP
Sbjct: 1046 GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPV 1105
Query: 1373 ASGRVQEAARPEE-VVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHR----P 1427
+ R + S +P+L+S ++ Q SS P D R
Sbjct: 1106 TELASRSPIRQDRGEFSASPMLKSGMSPEQS--RFQSDSSSYPTVDSNSLLGQSRLETAE 1163
Query: 1428 QKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPG--FPD---TDPSQVYSPGLPPAPA 1482
K + ED + RQ PFP PE F D T P + G P
Sbjct: 1164 SKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETK 1223
Query: 1483 QPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASNSEE 1542
+ +S P + + ++ + + P A Q L+ + + L E ++ +S E
Sbjct: 1224 EQNSALPTSSQDEELMEVVEKSEEP-----AGQILSHLSSEL---KEMSTSNFESSPEVE 1275
Query: 1543 KTPAPRLAAEKTKKEEYMKKLHMQERA 1569
+ PA L ++++ + ++ + + A
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMA 1302
Score = 61.6 bits (148), Expect = 6e-09
Identities = 301/1336 (22%), Positives = 456/1336 (34%), Gaps = 226/1336 (16%)
Query: 270 TRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRPL 329
+R + R+R + +R+R T R H+ R + + S R
Sbjct: 478 SRRMGRSRSPATAKRGRSRSRTPTKRG--HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSR 535
Query: 330 TPRTPA-RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEAT 388
+P+ P R R T+RR GR ++ + S+S ATR + R +R + ++ A
Sbjct: 536 SPQRPGWSRSRNTQRR----GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591
Query: 389 TRSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRADIGAASLSLFGDPYELDPFDSEEL 448
RSR +RT RR S P+ G R+ A S P S
Sbjct: 592 RRSR-SRTPTRRR--SRSRTPA-------RRGRSRSRTPARRRSRTRSPVRR---RSRSR 638
Query: 449 SANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDLLGSI 508
S S S R R +S P R G SR R PA P G
Sbjct: 639 SPARRSGRSRSRTPARRGRSRSRTPARR----GRSRSRTPAR--RSGRSRSRTPARRGRS 692
Query: 509 LSGQSLLMLGSSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSGSP 568
S S ++ R S S + QR S S E K R S S
Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSR------TPQRRGRSGSSSERKNKSRTSQRRSRSNS- 745
Query: 569 AQGPSGNRPQSTGLSCQGRSRTPARTAGAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHS 628
S +S S + RS + R+ A RL L R+LS S ++S +
Sbjct: 746 ----SPEMKKSRISSRRSRSLSSPRSK-AKSRLSL--------RRSLSGSSPCPKQKSQT 792
Query: 629 PWFNGTNKHTLPLASAAS--KISSRDSKPPCRSVVPGPPLKPAPRRTDISELPRIPKIRR 686
P + + P A + + + S S PP P K R++ S P PK+
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPP-----PKQKSKTPSRQSHSSSSPH-PKV-- 844
Query: 687 DDGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRV-PREPGVHTG 745
+ P SI P A E + P R + ES + R P H+
Sbjct: 845 ------KSGTPPRQGSITSPQA-------NEQSVTPQRRSCFESSPDPELKSRTPSRHSC 891
Query: 746 SSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPVDDK 805
S P + PSR ++ I P +HS S
Sbjct: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKA--IISPRQRSHSGSSS-------------- 935
Query: 806 EQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISIN 865
PSP S V + P S S +P S+ E LLP S
Sbjct: 936 ------PSP-----------SRVTSRTTPRRSRSVSPCSNVESR---LLPRYSHSGSSSP 975
Query: 866 SPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQ 925
K + R S ++ + + P GPS + SK E + D+ + S
Sbjct: 976 DTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK--SPCPQEKSKDSLVQSCPGSL 1033
Query: 926 GLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPE---APPSPDVLQAATH- 981
L A ++ +PP ++FG + + P+ SP+V Q+ +
Sbjct: 1034 SLCAGVKSSTPPG----------ESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES 1083
Query: 982 ---RVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGR------TRSGTRSE-SRDRSSRS 1031
+ P RS SSS + A R + ++ G +SG E SR +S S
Sbjct: 1084 PSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSS 1143
Query: 1032 ASPSV------GEERPRRQRSKAK-SRRSSSDRSSSRERAKRKKA--------------K 1070
+ P+V G+ R SK K + D ++S R K K + K
Sbjct: 1144 SYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFK 1203
Query: 1071 DKSR--EHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSL 1128
D R R G S T S P SS E +K + P G+ S SS
Sbjct: 1204 DTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEK----SEEPAGQILSHLSS- 1258
Query: 1129 ERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRS 1188
L S + + +V+ D+ + ++ + E P W
Sbjct: 1259 -ELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVE-------VPSMASSWGGPH- 1309
Query: 1189 HSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVA 1248
SPE K E S +PL + G L R ++ ++ K L P + ++
Sbjct: 1310 FSPEHK----ELSNSPLRENSFG-SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQL- 1363
Query: 1249 AECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPAL 1308
E +P LD+ + +GH + S DAV + MSS + SSP D P
Sbjct: 1364 -ETDP-SLDMKEQSTRSSGHSSSELSPDAV--EKAGMSS----NQSISSPVLD--AVPRT 1413
Query: 1309 PPASLAVAAIQREVSLMHDEDPSQ------PPPLPEGTQEP--HLLRPDAAEKAEAPSSP 1360
P + +A E+ PS+ P L +G+ P H L + + P +P
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473
Query: 1361 DVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAP 1420
+ + SP + + RP +P L ++ L + +E S + D+
Sbjct: 1474 SRGRSECDSSPEPKA-LPQTPRPRSRSPSSPELNNKCLTPQ-----RERSGSESSVDQKT 1527
Query: 1421 RAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLP-P 1479
A Q+ R G+ DV P+ Q SE D+ P P
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSE-------------SDSSPDSKAKTRTPLR 1574
Query: 1480 APAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPASEPASQATAASN 1539
++ S P S+ + + GS P V P + P +Q+ + S+
Sbjct: 1575 QRSRSGSSPEVDSKSRLSPRRSRSGSSPEV-------------KDKPRAAPRAQSGSDSS 1621
Query: 1540 SEEKTPAPRLAAEKTK 1555
E K PAPR +++
Sbjct: 1622 PEPKAPAPRALPRRSR 1637
Score = 31.2 bits (69), Expect = 8.7
Identities = 62/299 (20%), Positives = 99/299 (33%), Gaps = 27/299 (9%)
Query: 1141 SHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREA 1200
++ER + S R R S S+ R R P + Q S S +
Sbjct: 2389 AYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPR 2448
Query: 1201 SPAPLAQGEPGREDLPTRLPALGEAHVSP-EVATADKAPLQAPPVLEVAAECEPDDLDLD 1259
SP P A + R + P G +S VAT + +L V A P D
Sbjct: 2449 SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS---D 2505
Query: 1260 YGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAA-- 1317
G+ + + A+ + SS S S+ SS + S + +
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 1318 ----IQREVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSA 1373
+Q EV+L PS P E +E P A++ SS + + S S+
Sbjct: 2566 SSLPVQPEVAL--KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623
Query: 1374 SGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPRE 1432
S ++ S + S SS+P+ + L +P P++
Sbjct: 2624 SSSSSSSSSSSSSSSSSS---------------SSSSSSSPSPAKPGPQALPKPASPKK 2667
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 103 bits (257), Expect = 1e-21
Identities = 156/654 (23%), Positives = 256/654 (39%), Gaps = 94/654 (14%)
Query: 634 TNKHTLPLASAASKISSRDSKPPC-----RSVVPGP---PLKPAPRRTDISELPRIPKIR 685
++K ++ LA + S + + D KPP +S P P KPA R + P
Sbjct: 7 SSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMS----PSSS 62
Query: 686 RDDGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTG 745
+ AP++ S +R R T R ++A + R + G H+
Sbjct: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDT--RTSKASKASDVRCHQRRGTHSR 120
Query: 746 SSRPPAPSSHGSLAPLGPSRGKGVGSTFE-------SFRINIPGNMAHSSQLSSPGFCNT 798
P S S PSR G + R+ P + S+ S G
Sbjct: 121 GRTPGRRGSRSSKR--SPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYG---- 174
Query: 799 FRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEI 858
RP +R ++ + + L + Y P +G S+ + + P+ I
Sbjct: 175 -RPRTSNRERSDS--------QPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGI 225
Query: 859 TRTISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTER 918
++P + + V+ +G P S + +++ V + + T
Sbjct: 226 PSKEKSDNPSPSSSRKVKS---------YGQMIIPSREKSYSPTEMSSRVKSYNQASTRS 276
Query: 919 EEPTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVL-- 976
+ SQ + R R + + S R+ T ++ S
Sbjct: 277 RPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHS 336
Query: 977 ------QAATHRVVEL----RPPSRSRSTSSSRSRKKAKRKRVS----REHGRTRSGTRS 1022
Q+ T R R PS+ RS S SRS K + R S +E GR++SG+ +
Sbjct: 337 KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPN 396
Query: 1023 ESRDRSSRSASPSVGEERPR-------RQRSKAKSRRSSSDRSSSRERAK-----RKKAK 1070
+ RD S RS SP+ +R R R RS+++S + D S SR K R ++
Sbjct: 397 KQRDHS-RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
Query: 1071 DKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE----SRKKKKRRSASRPRGRECSPTS 1126
+K+R+H R + R RSRS SP S +H + S+++ RRS S + R+C +
Sbjct: 456 NKARDHSRSRSPNKAR-DRSRSRSP-SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR 513
Query: 1127 SLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRP---RSREKW 1183
S + H+ R S ER R++S + ++R + +SRSPS E R+ R P R R +W
Sbjct: 514 SSSKERDHRRSRSPSKER-QRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW 572
Query: 1184 PQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKA 1237
RS S ER+ +S R+ +R P + P ++ +KA
Sbjct: 573 ---RSPSKERERRQSRSS-------SEERDHSRSRSPNKQSGYSRPRASSKEKA 616
Score = 68.6 bits (166), Expect = 5e-11
Identities = 63/210 (30%), Positives = 86/210 (40%), Gaps = 23/210 (10%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRS-SRSASPSVGEERPRR 1043
+L PS+ R SRS K ++ R SR + R RS S + R S S +ER R
Sbjct: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS 546
Query: 1044 Q-RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPG-SSSYE 1101
Q RS ++ R RS S+ER +R+ RR S SRS SP S Y
Sbjct: 547 QSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYS 606
Query: 1102 HYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRR 1161
+ K+K S SR +E + H R S E + +V D +
Sbjct: 607 RPRASSKEKAHSRSRTPSKEGN----------HSQSRTSSKESDPSQSTVPRSPDWK--- 653
Query: 1162 SRSPSSEHRAREHRRPRSREKWPQTRSHSP 1191
RSP+ ++R P +T SHSP
Sbjct: 654 -RSPTRTSSLSQNRTP------SKTSSHSP 676
Score = 52.8 bits (125), Expect = 3e-06
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKR----VSREHGRTRSGTRSESRDRS-SRSASPSVGEERP 1041
R PS R SRS K + +R S+E R +S + SE RD S SRS + G RP
Sbjct: 549 RSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608
Query: 1042 R---------RQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGP-----WGHSRRT 1087
R R R+ +K S R+SS+E + +S + +R P +R
Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTP 668
Query: 1088 SRSRSGSP-----GSSSYEHYESRKKKKRRSASRPRGRECSPTSSL 1128
S++ S SP G + +S+ A+ P R S +S L
Sbjct: 669 SKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKL 714
Score = 43.1 bits (100), Expect = 0.002
Identities = 62/284 (21%), Positives = 108/284 (38%), Gaps = 38/284 (13%)
Query: 989 PSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKA 1048
P RS S S + + + + T+S + +RS P+ S
Sbjct: 4 PKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSK 63
Query: 1049 KSRRSSSDRSSSRERAKRKKAKDKSR----------------------EHRRGPWGHSRR 1086
++ +S+ R+ S + R + + K+R RRG HSR
Sbjct: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGT--HSRG 121
Query: 1087 TSRSRSGSPGSSSYEHYESRKKKKRRSASRP--RGRECSPTSSLERLCRHKHQRERSHER 1144
+ R GS S S + R +RP R +PTS + K R +S+ R
Sbjct: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTS------QQKGSRGKSYGR 175
Query: 1145 P---DRKESVAWPRDRRKRRSRSP--SSEHRAREHRRPRSREKWPQTRSHSPERKGAVRE 1199
P +R+ S + PR+ K+ R P S R+ E S K QT + P ++ +
Sbjct: 176 PRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKC-QTPTGIPSKEKSDNP 234
Query: 1200 ASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPP 1243
+ + G+ +P+R + +S V + ++A ++ P
Sbjct: 235 SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278
Score = 35.8 bits (81), Expect = 0.35
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 971 PSPDVLQAATHRVVELRPPSRSRSTSS----SRSRKKAKRKRVSREHGRTRSGTRSESRD 1026
PS + + + E R SRSRS + SR R +K K SR ++ G S+SR
Sbjct: 575 PSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRT 634
Query: 1027 RSSRS-ASPSVGEERPRRQRSKAKSRRSSSDRSSSR 1061
S S S S P +RS ++ S +R+ S+
Sbjct: 635 SSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 98.2 bits (243), Expect = 6e-20
Identities = 120/389 (30%), Positives = 169/389 (43%), Gaps = 46/389 (11%)
Query: 880 SYTVESIFGTEPEPPLGPSSA--MSKLRGAVAAEG---ASDTEREEPTESQGLAARLRRP 934
S +E I + PL P ++ LR + EG ASD R+ S +++ R
Sbjct: 1722 SANIEDINEADLVRPLLPKDMERLTSLRAGI--EGPLLASDVGRDRSAASPVVSSMPERA 1779
Query: 935 SPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDV-LQAATHRVVELRPPSRSR 993
S +++D + E++ + E D L++ + R SR R
Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKR 1839
Query: 994 STSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRS 1053
TS SRSR + + + +TRS +RS R RSSRS S S G RR SK K +RS
Sbjct: 1840 -TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRG----RRSVSKEKRKRS 1894
Query: 1054 SSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRS 1113
RS SRER KRK++ + +R+T R+RS +P S H SR+++ RS
Sbjct: 1895 PKHRSKSRER-KRKRSSSRD----------NRKTVRARSRTPSRRSRSHTPSRRRRS-RS 1942
Query: 1114 ASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRR-KRRSRSPSSEHRAR 1172
R R SP+ R R P R+ R R RRSR+PS R+R
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Query: 1173 EHRRPRSREKWP--QTRSHSPERKGAVREASPAPLAQ-----GEPGREDLPTRLPALGEA 1225
R RS P RS +P R R S +P+ + E GR P RL L +A
Sbjct: 2003 SVVRRRSFSISPVRLRRSRTPLR----RRFSRSPIRRKRSRSSERGRS--PKRLTDLDKA 2056
Query: 1226 HVSPEVATAD------KAPLQAPPVLEVA 1248
+ E+A A+ KA + PP L+ A
Sbjct: 2057 QLL-EIAKANAAAMCAKAGVPLPPNLKPA 2084
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 16/138 (11%)
Query: 264 RPRAGRTRAIARTRQSERVRATVNR------NRISTARRVQHTPGRLGSSLLDEAIEAVA 317
R R+ + R+ +R R+ +R + NR +R + R HTP R S +V
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS------RSVG 1944
Query: 318 TGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRK-KTPSGPS-AKSKSSATRSKKRQHR- 374
S ++ + RTP+RR R RR + P R+ +TPS S S+ S T S++R+ R
Sbjct: 1945 RRRSFSISPSRRS-RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Query: 375 VKKRRGKKVKSEATTRSR 392
V +RR + RSR
Sbjct: 2004 VVRRRSFSISPVRLRRSR 2021
Score = 34.7 bits (78), Expect = 0.79
Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 45/233 (19%)
Query: 169 IPVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCP 228
+P N S++ E+P + SD+ LL +G E PP + +P D F
Sbjct: 1668 LPSNNNLVSKDTEEPLPVK---ESDQTLAALLSPKESSGGEKEVPPPPKETLP-DSGF-- 1721
Query: 229 ECAAPGVVLAADAGPVSEEEV--SLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATV 286
+A+ ++E ++ LL D+ TS RAG + + + V
Sbjct: 1722 ---------SANIEDINEADLVRPLLPKDMERLTSL---RAGI--------EGPLLASDV 1761
Query: 287 NRNRISTARRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKK 346
R+R + + V P R S +E + Y+ + + + +K + R K
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDD----------YEIFVKVKDTHEKSKKNKNRDK 1811
Query: 347 VPGRKKTPSG---PSAKSKSSATRSKKR----QHRVKKRRGKKVKSEATTRSR 392
KK S S +SKSS +S+KR + R +KR K + TRSR
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSR 1864
Score = 34.3 bits (77), Expect = 1.0
Identities = 18/78 (23%), Positives = 38/78 (48%)
Query: 329 LTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEAT 388
L R+ + + + RK+ + S+KSKS ++++ R ++RR + +S++
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 389 TRSRIARTLGLRRPVHSS 406
R +++ R P H S
Sbjct: 1882 GRRSVSKEKRKRSPKHRS 1899
Score = 33.5 bits (75), Expect = 1.7
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 13/79 (16%)
Query: 336 RRKRKTRRRKKVPGRK-----KTPSGPSAKSKS-------SATRSKKRQHRVKKRR-GKK 382
RR+R +R R K GR+ K P +SKS S++R ++ R + R ++
Sbjct: 1869 RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Query: 383 VKSEATTRSRIARTLGLRR 401
+S +R R +R++G RR
Sbjct: 1929 SRSHTPSRRRRSRSVGRRR 1947
Score = 31.2 bits (69), Expect = 8.7
Identities = 22/92 (23%), Positives = 32/92 (34%), Gaps = 20/92 (21%)
Query: 1288 PPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLR 1347
P P + P + P+ P LPP E+P + P LP E L
Sbjct: 1151 PEEPPTMPPLPPEEPPMTPPLPP-----------------EEPPEGPALPT---EQSALT 1190
Query: 1348 PDAAEKAEAPSSPDVAPAGKEDSPSASGRVQE 1379
+ E PSSP + + P + + E
Sbjct: 1191 AENTWPTEVPSSPSEESVSQPEPPVSQSEISE 1222
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 98.2 bits (243), Expect = 6e-20
Identities = 120/389 (30%), Positives = 169/389 (43%), Gaps = 46/389 (11%)
Query: 880 SYTVESIFGTEPEPPLGPSSA--MSKLRGAVAAEG---ASDTEREEPTESQGLAARLRRP 934
S +E I + PL P ++ LR + EG ASD R+ S +++ R
Sbjct: 1722 SANIEDINEADLVRPLLPKDMERLTSLRAGI--EGPLLASDVGRDRSAASPVVSSMPERA 1779
Query: 935 SPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDV-LQAATHRVVELRPPSRSR 993
S +++D + E++ + E D L++ + R SR R
Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKR 1839
Query: 994 STSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRS 1053
TS SRSR + + + +TRS +RS R RSSRS S S G RR SK K +RS
Sbjct: 1840 -TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRG----RRSVSKEKRKRS 1894
Query: 1054 SSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRS 1113
RS SRER KRK++ + +R+T R+RS +P S H SR+++ RS
Sbjct: 1895 PKHRSKSRER-KRKRSSSRD----------NRKTVRARSRTPSRRSRSHTPSRRRRS-RS 1942
Query: 1114 ASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRR-KRRSRSPSSEHRAR 1172
R R SP+ R R P R+ R R RRSR+PS R+R
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Query: 1173 EHRRPRSREKWP--QTRSHSPERKGAVREASPAPLAQ-----GEPGREDLPTRLPALGEA 1225
R RS P RS +P R R S +P+ + E GR P RL L +A
Sbjct: 2003 SVVRRRSFSISPVRLRRSRTPLR----RRFSRSPIRRKRSRSSERGRS--PKRLTDLDKA 2056
Query: 1226 HVSPEVATAD------KAPLQAPPVLEVA 1248
+ E+A A+ KA + PP L+ A
Sbjct: 2057 QLL-EIAKANAAAMCAKAGVPLPPNLKPA 2084
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 16/138 (11%)
Query: 264 RPRAGRTRAIARTRQSERVRATVNR------NRISTARRVQHTPGRLGSSLLDEAIEAVA 317
R R+ + R+ +R R+ +R + NR +R + R HTP R S +V
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS------RSVG 1944
Query: 318 TGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRK-KTPSGPS-AKSKSSATRSKKRQHR- 374
S ++ + RTP+RR R RR + P R+ +TPS S S+ S T S++R+ R
Sbjct: 1945 RRRSFSISPSRRS-RTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Query: 375 VKKRRGKKVKSEATTRSR 392
V +RR + RSR
Sbjct: 2004 VVRRRSFSISPVRLRRSR 2021
Score = 34.7 bits (78), Expect = 0.79
Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 45/233 (19%)
Query: 169 IPVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCP 228
+P N S++ E+P + SD+ LL +G E PP + +P D F
Sbjct: 1668 LPSNNNLVSKDTEEPLPVK---ESDQTLAALLSPKESSGGEKEVPPPPKETLP-DSGF-- 1721
Query: 229 ECAAPGVVLAADAGPVSEEEV--SLLLADVVPTTSRLRPRAGRTRAIARTRQSERVRATV 286
+A+ ++E ++ LL D+ TS RAG + + + V
Sbjct: 1722 ---------SANIEDINEADLVRPLLPKDMERLTSL---RAGI--------EGPLLASDV 1761
Query: 287 NRNRISTARRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKK 346
R+R + + V P R S +E + Y+ + + + +K + R K
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDD----------YEIFVKVKDTHEKSKKNKNRDK 1811
Query: 347 VPGRKKTPSG---PSAKSKSSATRSKKR----QHRVKKRRGKKVKSEATTRSR 392
KK S S +SKSS +S+KR + R +KR K + TRSR
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSR 1864
Score = 34.3 bits (77), Expect = 1.0
Identities = 18/78 (23%), Positives = 38/78 (48%)
Query: 329 LTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEAT 388
L R+ + + + RK+ + S+KSKS ++++ R ++RR + +S++
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 389 TRSRIARTLGLRRPVHSS 406
R +++ R P H S
Sbjct: 1882 GRRSVSKEKRKRSPKHRS 1899
Score = 33.5 bits (75), Expect = 1.7
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 13/79 (16%)
Query: 336 RRKRKTRRRKKVPGRK-----KTPSGPSAKSKS-------SATRSKKRQHRVKKRR-GKK 382
RR+R +R R K GR+ K P +SKS S++R ++ R + R ++
Sbjct: 1869 RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Query: 383 VKSEATTRSRIARTLGLRR 401
+S +R R +R++G RR
Sbjct: 1929 SRSHTPSRRRRSRSVGRRR 1947
Score = 31.2 bits (69), Expect = 8.7
Identities = 22/92 (23%), Positives = 32/92 (34%), Gaps = 20/92 (21%)
Query: 1288 PPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLR 1347
P P + P + P+ P LPP E+P + P LP E L
Sbjct: 1151 PEEPPTMPPLPPEEPPMTPPLPP-----------------EEPPEGPALPT---EQSALT 1190
Query: 1348 PDAAEKAEAPSSPDVAPAGKEDSPSASGRVQE 1379
+ E PSSP + + P + + E
Sbjct: 1191 AENTWPTEVPSSPSEESVSQPEPPVSQSEISE 1222
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 89.7 bits (221), Expect = 2e-17
Identities = 75/239 (31%), Positives = 115/239 (48%), Gaps = 49/239 (20%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRS---SRSASPSVGEERPRR 1043
R SRSR + SRSR + + S+ R+RSG+RS S+ RS SRS S P +
Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252
Query: 1044 QRSKAKSRRSSSDRSSSRERAKRK------------------KAKDKSR---------EH 1076
++S+++S + RS S+++A+ K K+K KSR E
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312
Query: 1077 RRGPWGHSR------RTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLER 1130
+RG R R SRSRS S G S SR + + +S + +GR+ S S R
Sbjct: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGS-----RSRSRSRSKSKDKRKGRKRSREESRSR 367
Query: 1131 LCRHKHQRERSHERPDRKESVAWPRDRRKR------RSRSPS-SEHRAREHRRPRSREK 1182
R + + ERS +R +++S A ++K+ +SRSPS S + REH + S ++
Sbjct: 368 -SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
Score = 88.6 bits (218), Expect = 5e-17
Identities = 78/236 (33%), Positives = 114/236 (48%), Gaps = 37/236 (15%)
Query: 982 RVVELRPPSR-----SRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSV 1036
R+VE +P SR SRS S SRSR +++ R SR + + S+SR RS RS S
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS-RSGS--- 226
Query: 1037 GEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPG 1096
RS++KSR S RS S++ R +K+KSR HS SRS+S
Sbjct: 227 --------RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSR-----SHSAGKSRSKSKDQA 273
Query: 1097 SSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQ----RERSHE---RPDRKE 1149
++ ++ K K RS SR + + S + S ER + + R RS E R R
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 1150 SVAWPRDRRKRRSRSPSSE-----HRAREHRRPRSREKWPQTRSHSPERKGAVREA 1200
S + R + RSRS S + R+RE R RSR + ++S ++G+ R++
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSR---SKSERSRKRGSKRDS 386
Score = 74.7 bits (182), Expect = 7e-13
Identities = 80/238 (33%), Positives = 111/238 (46%), Gaps = 34/238 (14%)
Query: 990 SRSRSTSSSRSRKKAKR-----------KRVSREHGRTRSGTRSESRDRSSR-------S 1031
SRS S SRS+ K + K SR R +S ++S SR + R S
Sbjct: 257 SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
Query: 1032 ASPSVGEERPRRQ-RSKAKSRRSSSDRSSSRERAK-RKKAKDKSREHRRGPWGHSRRTSR 1089
S +E+ RQ RS+++S+ S RS SR ++K ++K + +SRE R SR S+
Sbjct: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR---SRSRSRSK 373
Query: 1090 S-RSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRK 1148
S RS GS S KKKK+ R + R S + S ER +H + S +R R
Sbjct: 374 SERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER----EHAKSESSQREGRG 429
Query: 1149 ESV-AWPRDRRKRRSRSPSSEHRAREHRRPRSREK-WPQTRSHSPERKGAVREASPAP 1204
ES A + RSRS +S+ + RSR K +TRS S R R AS +P
Sbjct: 430 ESENAGTNQETRSRSRS-NSKSKPNLPSESRSRSKSASKTRSRSKSRS---RSASRSP 483
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/211 (33%), Positives = 96/211 (45%), Gaps = 27/211 (12%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPR-RQR 1045
R PSR +S S SRSR + +R + G G E R SRS S S G R R R R
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVE-EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 1046 SKAKSRRSS------SDRSSSRERAK--RKKAKDKSREHRRGPWGHSRR--TSRSRSGSP 1095
SK+K +R RS SR R+K R + + R+ + G ++ T RS+S SP
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 1096 GSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPD-------RK 1148
S + E K + +S+ GR S + + R + R S +P+ R
Sbjct: 408 SRSVSKEREHAKSE----SSQREGRGESENAGTNQETRSR-SRSNSKSKPNLPSESRSRS 462
Query: 1149 ESVAWPRDRRKRRSRSPS---SEHRAREHRR 1176
+S + R R K RSRS S S R+R H R
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 52.0 bits (123), Expect = 5e-06
Identities = 44/159 (27%), Positives = 66/159 (41%), Gaps = 23/159 (14%)
Query: 1065 KRKKAKDKSREHRRGPWGHSRRTSRSRSGS---------PGSSSYEHYESRKKKKRRSAS 1115
K + +DK RR + SR SRSRS S GSS H +SR + + S S
Sbjct: 169 KIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS 228
Query: 1116 RPRGR-------------ECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRS 1162
R + R SP+ R H + RS + +E + + K +S
Sbjct: 229 RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 1163 RSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREAS 1201
RSP S H+++ R RS+E+ + +G +E S
Sbjct: 289 RSP-SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKS 326
Score = 52.0 bits (123), Expect = 5e-06
Identities = 46/136 (33%), Positives = 63/136 (46%), Gaps = 30/136 (22%)
Query: 985 ELRPPSRSRSTSSSRSRKKA-----------KRKRVSREHGRTRSGTRS----------E 1023
E R SRSRS S RSRK+ K+K+ + ++RS +RS E
Sbjct: 363 ESRSRSRSRS-KSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE 421
Query: 1024 SRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAK-----RKKAKDKSREHRR 1078
S R R S + G + R RS++ S+ + S SR R+K R ++K +SR R
Sbjct: 422 SSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
Query: 1079 GPWGHSRRTSRSRSGS 1094
P SR SRS S S
Sbjct: 482 SP---SRSRSRSHSRS 494
Score = 41.2 bits (95), Expect = 0.008
Identities = 43/164 (26%), Positives = 78/164 (47%), Gaps = 32/164 (19%)
Query: 261 SRLRPRAG-RTRAIARTRQSERVRATVNRNRIST---ARRVQHTPGRLGSSLLDEAIEAV 316
SR R R+G R+R+ +R+R R R+ ++R + +R H+ G+ S D+A E +
Sbjct: 218 SRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI 277
Query: 317 ATGLSTAVYQRPLTPRTPARRKRKTRRRKKVP--------------GRKKTPSGPSAKSK 362
+ +P + R+P+R K K++ R + GR + S ++S+
Sbjct: 278 QNNDNVG---KPKS-RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 363 S-----SATRSKKRQHRVKKRRGKK-----VKSEATTRSRIART 396
S S +RS+ R KR+G+K +S + +RS+ R+
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
Score = 34.7 bits (78), Expect = 0.79
Identities = 30/126 (23%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 269 RTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVATGLSTAVYQRP 328
++R+ +R + + R+ R+ +R + GR L ++ + + R
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 329 LTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRG--KKVKSE 386
R+ ++ KRK R+R + R + ++S+S + RS+KR + + G KK K E
Sbjct: 347 ---RSKSKDKRKGRKRSREESRSR------SRSRSKSERSRKRGSKRDSKAGSSKKKKKE 397
Query: 387 ATTRSR 392
T RS+
Sbjct: 398 DTDRSQ 403
Score = 32.0 bits (71), Expect = 5.1
Identities = 17/61 (27%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 334 PARRKRKTRRRKKVPGRKKTPSGPSAK--SKSSATRSKKRQHRVKKRRGKKVKSEATTRS 391
P R+R++ R + R ++ S S K S+S +++S + R + R G + +S++ +RS
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 392 R 392
+
Sbjct: 237 Q 237
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 89.4 bits (220), Expect = 3e-17
Identities = 70/215 (32%), Positives = 96/215 (44%), Gaps = 32/215 (14%)
Query: 990 SRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAK 1049
SRSRS S R RK R R R++ G R ES+D+SS+ EE ++ S K
Sbjct: 41 SRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHK---SEEHNDKEHSSDK 97
Query: 1050 SRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKK 1109
R + + +R KRK+ R++SR RS S S + SR ++
Sbjct: 98 GRERLNSSENGEDRHKRKE----------------RKSSRGRSHSRSRSRERRHRSRSRE 141
Query: 1110 KRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEH 1169
+++S SR R R+ S + S ER K R RS ER R R R + RSR H
Sbjct: 142 RKKSRSRSRERKKSRSRSRER----KKSRSRSRERKRR------IRSRSRSRSR---HRH 188
Query: 1170 RAREHRRPRSREKWPQTRSHSPERKGAVREASPAP 1204
R R R RSR + + R P R +P+P
Sbjct: 189 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
Score = 82.0 bits (201), Expect = 4e-15
Identities = 65/196 (33%), Positives = 102/196 (52%), Gaps = 17/196 (8%)
Query: 1018 SGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSD------RSSSRER-AKRKKAK 1070
S R + +++S S SP + R RS+++ R+ SD RS SR + +R ++K
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
Query: 1071 DKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLER 1130
DKS + + H+ + S G +S E+ E R K+K R +SR GR S + S ER
Sbjct: 77 DKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR--GRSHSRSRSRER 133
Query: 1131 LCRHK-HQRERSHERP-DRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKW----- 1183
R + +R++S R +RK+S + R+R+K RSRS + R R R RSR +
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR 193
Query: 1184 PQTRSHSPERKGAVRE 1199
+TRS S +RK + +
Sbjct: 194 SRTRSRSRDRKKRIEK 209
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 34/166 (20%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R SR R S SRSR++ K SR R R +RS SR+R R R RS
Sbjct: 136 RSRSRERKKSRSRSRERKK----SRSRSRERKKSRSRSRERKRRI-----------RSRS 180
Query: 1047 KAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESR 1106
+++SR RS SR R++ + K + + RR SR SR+ S P +++
Sbjct: 181 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR----FSRSLSRTPSPPPFRGRNTAMDAQ 236
Query: 1107 KKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVA 1152
+ RR LER + + QRE+ +++ +A
Sbjct: 237 EALARR---------------LERAKKLQEQREKEMVEKQKQQEIA 267
Score = 40.0 bits (92), Expect = 0.019
Identities = 43/155 (27%), Positives = 62/155 (40%), Gaps = 30/155 (19%)
Query: 1051 RRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKK 1110
R + +S +R K+K+ + S R +SR SRSR S + E RK +
Sbjct: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDN----EGRKHRS 63
Query: 1111 RRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHR 1170
R + R E SS ++ +S E D++ S K R R SSE+
Sbjct: 64 RSRSKEGRRHESKDKSS---------KKHKSEEHNDKEHS------SDKGRERLNSSENG 108
Query: 1171 AREHRR-----------PRSREKWPQTRSHSPERK 1194
H+R RSR + + RS S ERK
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERK 143
Score = 35.0 bits (79), Expect = 0.60
Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Query: 332 RTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRS 391
R+ +R ++K+R R + RKK+ S S + K S +RS++R+ R++ R + + TRS
Sbjct: 136 RSRSRERKKSRSRSRE--RKKSRSR-SRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
Query: 392 R 392
R
Sbjct: 193 R 193
Score = 34.3 bits (77), Expect = 1.0
Identities = 23/90 (25%), Positives = 37/90 (41%)
Query: 986 LRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQR 1045
+R SRSRS R+R +++ + SR+ + R SR S + P
Sbjct: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 235
Query: 1046 SKAKSRRSSSDRSSSRERAKRKKAKDKSRE 1075
+A +RR + +R K K K +E
Sbjct: 236 QEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 31.2 bits (69), Expect = 8.7
Identities = 16/56 (28%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 337 RKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSR 392
R+R+ R R + + ++ S KS+S + KK + R ++R+ ++++S + +RSR
Sbjct: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSR 185
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 84.3 bits (207), Expect = 9e-16
Identities = 82/287 (28%), Positives = 119/287 (41%), Gaps = 54/287 (18%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R S +RS S S S+ ++RKR +H R+RS RS SR + R + + P ++RS
Sbjct: 307 RSRSHTRSKSRSSSKSHSRRKRSQSKH-RSRSHNRSRSRQKDRRRS------KSPHKKRS 359
Query: 1047 KAKSRRSSSDRSSSRERAK----------RKKAKDKSREHRRGPWGHSRRTSRSRSGSPG 1096
K++ RR S RS SR++ K R K KD+ +E R R G
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER----EKEREKEKERGKNK 415
Query: 1097 SSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHER------------ 1144
E + R+K K + R R +E E+ ++ER +R
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Query: 1145 ----PDR-----KESVAWPRDRRKRRSRSPSSEHRA-----REHRR---PRSR----EKW 1183
P R + S + R+RR+RRSRS S R R+ R PRSR +K
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535
Query: 1184 PQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPE 1230
+ R H ER+ R S + G+E L +L E + E
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582
Score = 74.3 bits (181), Expect = 9e-13
Identities = 68/256 (26%), Positives = 116/256 (45%), Gaps = 43/256 (16%)
Query: 964 VVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSE 1023
V PE P QAA + E+ R + S + + K R+ GR+RS TRS+
Sbjct: 261 VKPPEMTP-----QAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 315
Query: 1024 SRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGH 1083
SR SS+S S RR+RS++K R S +RS SR++ +R+ H++
Sbjct: 316 SRS-SSKSHS--------RRKRSQSKHRSRSHNRSRSRQKDRRRSKSP----HKKRSKSR 362
Query: 1084 SRRTSRSRSGS--------------------PGSSSYEHYESRKKKKRRSASRPRGRECS 1123
RR SRSRS S E + R+K+K R ++ R +E
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 422
Query: 1124 PTSSLERLCRHKHQRERSHERP-DRKESVAWPRDRRKRRSRSPSSEHRAREHRR----PR 1178
++ + +RE+ HE+ D+++ +++ + + RS + + ++ ++ PR
Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 482
Query: 1179 SREKWPQTRSHSPERK 1194
S ++RS S ER+
Sbjct: 483 SYNASRRSRSSSRERR 498
Score = 58.9 bits (141), Expect = 4e-08
Identities = 43/217 (19%), Positives = 95/217 (43%), Gaps = 16/217 (7%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQ 1044
+++ R + + R++ K + +E G+ + + +DR E +
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442
Query: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE 1104
+ + K + D+ RE+ + K+ +K ++ ++ SR RS + S S S
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-----SRTPPRSYNASRRSRS----S 493
Query: 1105 SRKKKKRRSASRPRGRECSPT----SSLERLCRHKHQRERSHERPDRKESVAWPRDRRKR 1160
SR++++RRS S R S T SS R ++++++ E+ ++ ++ R+R +
Sbjct: 494 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK--ERDHISERRERERS 551
Query: 1161 RSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAV 1197
S SS R + + ++ + + H+ E +V
Sbjct: 552 TSMRKSSNDRDGKEKLEKNSTSLKE-KEHNKEPDSSV 587
Score = 56.6 bits (135), Expect = 2e-07
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 26/214 (12%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R +R + R ++K + K RE R + R +++DR ++ R+R
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Query: 1047 KAKSRRSSSDRSSSRERAKRK-KAKDKSRE----------HRRGPWGH-----SRRTSRS 1090
+ K D+ +E+ K K + KD+S+E R P + SR +SR
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496
Query: 1091 RSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKES 1150
R SS + K KR+S+ P SP S ++ + + +R+ ER +R+ S
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSP-----SPRSRNKKDKKREKERDHISERRERERS 551
Query: 1151 VAW-----PRDRRKRRSRSPSSEHRAREHRRPRS 1179
+ RD +++ ++ +S ++ P S
Sbjct: 552 TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Score = 47.4 bits (111), Expect = 1e-04
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKS 1050
+ + R R+K K +E + + + +DRS + E+R + ++S+
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-----EIDEKRKKDKKSRTPP 481
Query: 1051 R---RSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRK 1107
R S RSSSRER +R++++ SR R S+ R S SP S + ++
Sbjct: 482 RSYNASRRSRSSSRER-RRRRSRSSSRSPRT-----SKTIKRKSSRSPSPRSRNKKDKKR 535
Query: 1108 KKKRRSASRPRGRECSPT---SSLERLCRHKHQ------RERSHER-PDRKES 1150
+K+R S R RE S + SS +R + K + +E+ H + PD S
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 588
Score = 36.2 bits (82), Expect = 0.27
Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 335 ARRKRKTRRRKKVPGRKKTPSGPSAKSKS-SATRSKKRQHRVKKRRGKKVKSEATTRSR 392
+R ++K RRR K P +K++ S KS+S S +R K++ R K + ++VK + + R
Sbjct: 341 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 399
Score = 32.3 bits (72), Expect = 3.9
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 336 RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKR 378
RR+R++R + P KT S++S S +R+KK + R K+R
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKER 539
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 84.3 bits (207), Expect = 9e-16
Identities = 82/287 (28%), Positives = 119/287 (41%), Gaps = 54/287 (18%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R S +RS S S S+ ++RKR +H R+RS RS SR + R + + P ++RS
Sbjct: 191 RSRSHTRSKSRSSSKSHSRRKRSQSKH-RSRSHNRSRSRQKDRRRS------KSPHKKRS 243
Query: 1047 KAKSRRSSSDRSSSRERAK----------RKKAKDKSREHRRGPWGHSRRTSRSRSGSPG 1096
K++ RR S RS SR++ K R K KD+ +E R R G
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER----EKEREKEKERGKNK 299
Query: 1097 SSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHER------------ 1144
E + R+K K + R R +E E+ ++ER +R
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 1145 ----PDR-----KESVAWPRDRRKRRSRSPSSEHRA-----REHRR---PRSR----EKW 1183
P R + S + R+RR+RRSRS S R R+ R PRSR +K
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 1184 PQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPE 1230
+ R H ER+ R S + G+E L +L E + E
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466
Score = 74.3 bits (181), Expect = 9e-13
Identities = 68/256 (26%), Positives = 116/256 (45%), Gaps = 43/256 (16%)
Query: 964 VVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSE 1023
V PE P QAA + E+ R + S + + K R+ GR+RS TRS+
Sbjct: 145 VKPPEMTP-----QAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 199
Query: 1024 SRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGH 1083
SR SS+S S RR+RS++K R S +RS SR++ +R+ H++
Sbjct: 200 SRS-SSKSHS--------RRKRSQSKHRSRSHNRSRSRQKDRRRSKSP----HKKRSKSR 246
Query: 1084 SRRTSRSRSGS--------------------PGSSSYEHYESRKKKKRRSASRPRGRECS 1123
RR SRSRS S E + R+K+K R ++ R +E
Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 306
Query: 1124 PTSSLERLCRHKHQRERSHERP-DRKESVAWPRDRRKRRSRSPSSEHRAREHRR----PR 1178
++ + +RE+ HE+ D+++ +++ + + RS + + ++ ++ PR
Sbjct: 307 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 366
Query: 1179 SREKWPQTRSHSPERK 1194
S ++RS S ER+
Sbjct: 367 SYNASRRSRSSSRERR 382
Score = 58.9 bits (141), Expect = 4e-08
Identities = 43/217 (19%), Positives = 95/217 (43%), Gaps = 16/217 (7%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQ 1044
+++ R + + R++ K + +E G+ + + +DR E +
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326
Query: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE 1104
+ + K + D+ RE+ + K+ +K ++ ++ SR RS + S S S
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-----SRTPPRSYNASRRSRS----S 377
Query: 1105 SRKKKKRRSASRPRGRECSPT----SSLERLCRHKHQRERSHERPDRKESVAWPRDRRKR 1160
SR++++RRS S R S T SS R ++++++ E+ ++ ++ R+R +
Sbjct: 378 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK--ERDHISERRERERS 435
Query: 1161 RSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAV 1197
S SS R + + ++ + + H+ E +V
Sbjct: 436 TSMRKSSNDRDGKEKLEKNSTSLKE-KEHNKEPDSSV 471
Score = 56.6 bits (135), Expect = 2e-07
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 26/214 (12%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R +R + R ++K + K RE R + R +++DR ++ R+R
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Query: 1047 KAKSRRSSSDRSSSRERAKRK-KAKDKSRE----------HRRGPWGH-----SRRTSRS 1090
+ K D+ +E+ K K + KD+S+E R P + SR +SR
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380
Query: 1091 RSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKES 1150
R SS + K KR+S+ P SP S ++ + + +R+ ER +R+ S
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSP-----SPRSRNKKDKKREKERDHISERRERERS 435
Query: 1151 VAW-----PRDRRKRRSRSPSSEHRAREHRRPRS 1179
+ RD +++ ++ +S ++ P S
Sbjct: 436 TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469
Score = 47.4 bits (111), Expect = 1e-04
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKS 1050
+ + R R+K K +E + + + +DRS + E+R + ++S+
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-----EIDEKRKKDKKSRTPP 365
Query: 1051 R---RSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRK 1107
R S RSSSRER +R++++ SR R S+ R S SP S + ++
Sbjct: 366 RSYNASRRSRSSSRER-RRRRSRSSSRSPRT-----SKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 1108 KKKRRSASRPRGRECSPT---SSLERLCRHKHQ------RERSHER-PDRKES 1150
+K+R S R RE S + SS +R + K + +E+ H + PD S
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 472
Score = 36.2 bits (82), Expect = 0.27
Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 335 ARRKRKTRRRKKVPGRKKTPSGPSAKSKS-SATRSKKRQHRVKKRRGKKVKSEATTRSR 392
+R ++K RRR K P +K++ S KS+S S +R K++ R K + ++VK + + R
Sbjct: 225 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 283
Score = 32.3 bits (72), Expect = 3.9
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 336 RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKR 378
RR+R++R + P KT S++S S +R+KK + R K+R
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKER 423
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 83.6 bits (205), Expect = 1e-15
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 38/345 (11%)
Query: 893 PPLGPSSAMSKL---RGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCS 949
P P+S +L R +G P+ S+ R RR P W +E +
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRS-RDRFRRSETPPHWRQEMQRAQR 371
Query: 950 TFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRV 1009
S ER + E + Q + RV E R + R+ S S +RK K K+V
Sbjct: 372 MRVSSGERWIKGDKSELNEIKEN----QRSPVRVKE-RKITDHRNVSESPNRKNEKEKKV 426
Query: 1010 SREHGRTRSGTRSESRDRSSRSASPSVGEERPR-RQRSKAKSRRSSSDRSSSRER----- 1063
++H +S S++R R S + + + ++R+K+KSR S ++S S+ER
Sbjct: 427 -KDH-------KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHN 478
Query: 1064 ---AKRKKAKDKSREHRR--------GPWGHSRRTSRSRSGSPG--SSSYEHYESRKKKK 1110
KR +++ K R+H G + SRS+ S S S EH S+ K+K
Sbjct: 479 RNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEK 538
Query: 1111 RRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHR 1170
R A + R REC T +R RS +R R S RDR + + E
Sbjct: 539 DRRA-QSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 1171 AREHRRPRSRE-KWPQTRSHSPERKGAVREASPAPLAQGEPGRED 1214
R R RSRE + P RS S +R+ R++ + + + +D
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKD 642
Score = 74.7 bits (182), Expect = 7e-13
Identities = 60/210 (28%), Positives = 96/210 (45%), Gaps = 21/210 (10%)
Query: 999 RSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRS 1058
+ R K+K + S+E +++ +R+ R S S G + + + +S D+
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQE 512
Query: 1059 SSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEH-YESRKKKKRRSASRP 1117
SR + K K+ + KS EH R ++SRS + +H Y SR +++ RS R
Sbjct: 513 RSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRS 572
Query: 1118 R-------GRECSPTSSLERLCRHKHQ---RERSHER---PDRKESVAWPRDRRKRRSRS 1164
R R+ S + R +++ R RS ER P R S +DRR+RR S
Sbjct: 573 RRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRS----KDRRRRRRDS 628
Query: 1165 PSSEHRAREHRRPRSREKWPQTRSHSPERK 1194
SSE RE + R+++K+ S S RK
Sbjct: 629 RSSE---REESQSRNKDKYRNQESKSSHRK 655
Score = 72.4 bits (176), Expect = 3e-12
Identities = 70/240 (29%), Positives = 118/240 (49%), Gaps = 34/240 (14%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRT---RSGTRSESRD----RSSRSASPSVGEERPRR 1043
R++S S S+S++K+K K +H R R +RS+ RD + S S G+++ R
Sbjct: 455 RAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQ-ER 513
Query: 1044 QRSKAKSRRSSS-----DRSSSRERAKRKKAKDKSREHRRGPWGHSRRT-----SRSRSG 1093
RSK KS++ S D S S+E+ +R +++ + + +G ++ RT SR RS
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR 573
Query: 1094 SPGSSSYEHYESRKKK---------KRRSASRPRGRECSPTSSLERLCRHKHQRERSHER 1144
S +++ SR K+ +RR SR R R P S + R + + RS ER
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 633
Query: 1145 PDRKESVAWPRDRRKRRSRSPSSEHR--AREHRRPRSREKWPQTRSHSPERKGAVREASP 1202
+ES + +D+ R S SS + + +R S+ + + ++S E+K A R+ SP
Sbjct: 634 ---EESQSRNKDKY-RNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK-ADRDQSP 688
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/231 (26%), Positives = 103/231 (44%), Gaps = 46/231 (19%)
Query: 983 VVELRPPSRSRSTSSSRSRKKAKRKRV---SREHGRTRS---GTRSESRDR--------- 1027
V E S S+ RSR K K K++ S EH ++S R++SR R
Sbjct: 497 VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKH 556
Query: 1028 --SSRSASPSVGEERPRRQRSKA--KSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGH 1083
+SR+ S +R RR RS+ + R S + RE+ R++ + +SRE RR P G
Sbjct: 557 SYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRE-RRTPPGR 615
Query: 1084 SRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHE 1143
SR S+ +++RR SR RE S + + + ++++Q +S
Sbjct: 616 SR-------------------SKDRRRRRRDSRSSEREESQSRNKD---KYRNQESKSSH 653
Query: 1144 RPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERK 1194
R + ES R +SR +S + +RE + R + + + + S + +
Sbjct: 654 RKENSES----EKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNE 700
Score = 55.1 bits (131), Expect = 6e-07
Identities = 48/190 (25%), Positives = 74/190 (38%), Gaps = 15/190 (7%)
Query: 1002 KKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSR 1061
KK ++KR + S + S+S S S+ S E + K K + + R +
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243
Query: 1062 ERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRK------KKKRRSAS 1115
E+ KRKK+K + ++ S R + RK +K+R++
Sbjct: 244 EKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRE 303
Query: 1116 RPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHR 1175
R R REC+P +S +QR R RK + R RR R+PS R
Sbjct: 304 RERERECNPPNSQPA----SYQRRLLVTRSGRK-----IKGRGPRRYRTPSRSRSRDRFR 354
Query: 1176 RPRSREKWPQ 1185
R + W Q
Sbjct: 355 RSETPPHWRQ 364
Score = 48.1 bits (113), Expect = 7e-05
Identities = 69/291 (23%), Positives = 109/291 (37%), Gaps = 74/291 (25%)
Query: 963 TVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRS 1022
TV E PP P+ +R + + P ++ + RK +R+R RE S S
Sbjct: 271 TVRPEEIPPIPE------NRFLMRKSPPKA----DEKERKNRERER-ERECNPPNSQPAS 319
Query: 1023 ESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSS--------SRERAKRKKAK---- 1070
R + + PRR R+ ++SR R S +RA+R +
Sbjct: 320 YQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGER 379
Query: 1071 ----DKS-----REHRRGPWGHSRR---------------------------TSRSRSGS 1094
DKS +E++R P R S+ R
Sbjct: 380 WIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIR 439
Query: 1095 PGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRE---------RSHERP 1145
S + Y+++ KK+ +S SR + +E S S ER +H E R HE
Sbjct: 440 RNSEKDDKYKNKVKKRAKSKSRSKSKEKS--KSKERDSKHNRNEEKRMRSRSKGRDHENV 497
Query: 1146 DRKESVAWPRDRRKRRSRSPSS----EHRAREHRRPRSREKWPQTRSHSPE 1192
KE + + + + RSRS E ++ EH +S+EK + +S S E
Sbjct: 498 KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRE 548
Score = 42.0 bits (97), Expect = 0.005
Identities = 56/234 (23%), Positives = 94/234 (40%), Gaps = 53/234 (22%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
+P + R S K+K K+ ++ ++ S + S S D S S S
Sbjct: 164 KPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDS------------- 210
Query: 1047 KAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESR 1106
+SSSD S S E A +K+K + ++HR+ H +
Sbjct: 211 -----QSSSDSSDS-ESATEEKSKKRKKKHRKNSRKH----------------------K 242
Query: 1107 KKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPS 1166
K+KK+R S+ S +LE + +S RP+ + P +R R P
Sbjct: 243 KEKKKRKKSKKSASSESEAENLE-------AQPQSTVRPEEIPPI--PENRFLMRKSPPK 293
Query: 1167 SEHRAREHR-RPRSRE-KWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTR 1218
++ + R++R R R RE P ++ S +R+ V + +G P R P+R
Sbjct: 294 ADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRG-PRRYRTPSR 346
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 81.6 bits (200), Expect = 6e-15
Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 18/232 (7%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGT--------RSESRDRSSRSASPSVGEERPR 1042
RSRS S S +++ R+ SR H R G+ R + R R R A E R
Sbjct: 259 RSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRS 318
Query: 1043 RQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEH 1102
R + RR S R R R++ + K R+ R R + G Y+
Sbjct: 319 RSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR------EREKENERGRRRDRDYDK 372
Query: 1103 YESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRS 1162
+++K R SR R +E +E +HK ++ R D+++S ++++ RS
Sbjct: 373 ERGNEREKERERSRERSKEQRSRGEVEEK-KHKEDKDDRRHRDDKRDS---KKEKKHSRS 428
Query: 1163 RSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGRED 1214
RS +HR+R R + +++ S + K +E S G GR D
Sbjct: 429 RSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD 480
Score = 75.9 bits (185), Expect = 3e-13
Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 23/234 (9%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQ 1044
E + + R S S R +R+ SRE R+RS +R DR R ER RR+
Sbjct: 307 EAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRR 366
Query: 1045 ---RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101
K + +R SRER+K ++++ + E + RR + S +
Sbjct: 367 DRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHS 426
Query: 1102 HYESRKKKKR-RSASRPRGRECSPTSSLERLCRHKHQ-RERSHER-----PDRKESVAWP 1154
SR++K R RS SR G+ S + S E+ +HK++ +E+S++R R +SV
Sbjct: 427 RSRSRERKHRSRSRSRNAGKR-SRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSV--- 482
Query: 1155 RDRRKRRSRSPSSE-------HRAREHRRPRSREKWPQTRSHSPERKGAVREAS 1201
++ K+R SPS E + R H+R S K Q+ H R ++ + S
Sbjct: 483 -EKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSK-DQSDKHDRRRSQSIEQES 534
Score = 72.0 bits (175), Expect = 4e-12
Identities = 67/221 (30%), Positives = 96/221 (43%), Gaps = 28/221 (12%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R SR R S SRSR + K R R+ R + R RDR + E+ R R
Sbjct: 329 RSRSRERHRSRSRSRDR-KGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRE 387
Query: 1047 KAKSRRS---------SSDRSSSRER-----AKRKKAKDKSREHRRGPWGHSRRTS---R 1089
++K +RS D+ R R +K++K +SR R SR + R
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR 447
Query: 1090 SRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKE 1149
SRS S SS ES++K +RS S +GR S S +R H +E+S +R KE
Sbjct: 448 SRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKR--EHSPSKEKSRKRSRSKE 505
Query: 1150 SVAWPRDRRKRRSRSPSSEHRAR-EHRRPRSREKWPQTRSH 1189
R +R S S + + + RR +S E+ Q + H
Sbjct: 506 -------RSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539
Score = 36.2 bits (82), Expect = 0.27
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 11/92 (11%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHG--RTRSGTRSESRDRS-SRSASPSVGEERP 1041
E + S RS S S+ R + K REH + +S RS S++RS R S S
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDS------ 515
Query: 1042 RRQRSKAKSRRSSSDRSSSRERAKRKKAKDKS 1073
+ Q K RRS S S+E K+ K KD++
Sbjct: 516 KDQSDKHDRRRSQSIEQESQE--KQHKNKDET 545
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 78.6 bits (192), Expect = 5e-14
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 14/194 (7%)
Query: 989 PSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKA 1048
P R + + R++ ++++ RE R R + E + R R G+ER R+++ +
Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER----GKERERKRKERE 83
Query: 1049 KSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKK 1108
K R+ ++ ER KRKK K K +RG ++ R E +++
Sbjct: 84 KQRKERREK----ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
Query: 1109 KKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSE 1168
KK+R R R +E +R R K +RE+ ER +RKE + R+R+ R +
Sbjct: 140 KKKRRKERKREKERGKRER-KRKKRKKEEREKKRER-NRKER----KKERERKERRERKK 193
Query: 1169 HRAREHRRPRSREK 1182
R +E R+ + R+K
Sbjct: 194 ERKKERRKKKERKK 207
Score = 73.2 bits (178), Expect = 2e-12
Identities = 57/208 (27%), Positives = 91/208 (43%), Gaps = 30/208 (14%)
Query: 991 RSRSTSSSRSR-KKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAK 1049
R R R R KK K+KR RE G+ R R R R E+ RR+R K K
Sbjct: 48 REREKERKRERGKKEKKKRKKRERGKERE------RKRKEREKQRKERREKERRKRKKEK 101
Query: 1050 SRRSSSDRSSSRERAKRKKAKDKSREHR-RGPWGHSRRTSRSRSGSPGSSSYEHYESRKK 1108
+R R RER K+K+ K++ RE++ R +R + R RK+
Sbjct: 102 KKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKR 160
Query: 1109 KKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSE 1168
KKR+ R + RE R++ +R++ ER +R R+R+K R +
Sbjct: 161 KKRKKEEREKKRE-----------RNRKERKKERERKER-------RERKKERKK---ER 199
Query: 1169 HRAREHRRPRSREKWPQTRSHSPERKGA 1196
+ +E ++ R ++ ++ P R+ A
Sbjct: 200 RKKKERKKDRKTDRQTDSQVFRPLRESA 227
Score = 71.2 bits (173), Expect = 8e-12
Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 24/221 (10%)
Query: 977 QAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSV 1036
+AA EL+ S S + R+ ++K R R + R+R +
Sbjct: 8 RAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEK---- 63
Query: 1037 GEERPRRQRSKAKSRR---SSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSG 1093
++R +R+R K + R+ R RE+ +RK+ K+K + R+ R+ + R
Sbjct: 64 -KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
Query: 1094 SPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAW 1153
+ RKK++++ + R RE + + +RER ++ ++E
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKERKRE-----------KERGKRERKRKKRKKEE---- 167
Query: 1154 PRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERK 1194
R++++ R+R + R R+ RR R +E+ + R +K
Sbjct: 168 -REKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 62.8 bits (151), Expect = 3e-09
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 12/162 (7%)
Query: 1038 EERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGS 1097
E +++R + + R+ ++ RER K++K K K RE RG +R R +
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRE--RGKERERKRKEREK------ 84
Query: 1098 SSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDR 1157
+ E R+K++R+ + RE ER + K ++ER E R+E R +
Sbjct: 85 ---QRKERREKERRKRKKEKKKRERKQRGRRERK-KKKERKERERENKQRRERKRKKRRK 140
Query: 1158 RKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVRE 1199
+KRR + R + R+ + R+K + + RK +E
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKE 182
Score = 58.5 bits (140), Expect = 5e-08
Identities = 42/154 (27%), Positives = 72/154 (46%), Gaps = 15/154 (9%)
Query: 1046 SKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYES 1105
SK ++R S + RER KRK+ ++K R+ RG +R R R G + E
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER-GKERERKRKEREK 84
Query: 1106 RKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSP 1165
++K++R R R +E ER R + +R++ ER +R+ R+ ++RR R
Sbjct: 85 QRKERREKERRKRKKE---KKKRERKQRGRRERKKKKERKERE------RENKQRRERK- 134
Query: 1166 SSEHRAREHRRPRSREKWPQTRSHSPERKGAVRE 1199
R + ++ R +E+ + ERK R+
Sbjct: 135 ----RKKRRKKKRRKERKREKERGKRERKRKKRK 164
Score = 52.4 bits (124), Expect = 4e-06
Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 9/137 (6%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQ 1044
E + R R ++K KR+R ++ GR + E ++R + + + RR+
Sbjct: 83 EKQRKERREKERRKRKKEKKKRER--KQRGRRERKKKKERKERERENKQRRERKRKKRRK 140
Query: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE 1104
+ + K R+ +R RER KRKK K + RE +R R+ R R E +
Sbjct: 141 KKRRKERKREKER-GKRER-KRKKRKKEEREKKRERNRKERKKERER-----KERRERKK 193
Query: 1105 SRKKKKRRSASRPRGRE 1121
RKK++R+ R + R+
Sbjct: 194 ERKKERRKKKERKKDRK 210
Score = 38.1 bits (87), Expect = 0.071
Identities = 20/72 (27%), Positives = 36/72 (50%)
Query: 326 QRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKS 385
+R R +RK++ R +K+ RK+ K + + +K++ R KK R K K+
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
Query: 386 EATTRSRIARTL 397
+ T S++ R L
Sbjct: 212 DRQTDSQVFRPL 223
Score = 35.8 bits (81), Expect = 0.35
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRS-GTRSESRDRSSRSASPSVGEERPRRQR 1045
R + R RK+ KRK+ RE R R+ R + R+R R ++ R+++
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 1046 SKAKSRRSSSDRSSSRERAKRKKA 1069
+ K R++ S R R+ A
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESA 227
Score = 32.7 bits (73), Expect = 3.0
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 336 RRKRKTRRRKKVPG---RKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSE 386
R+K K +R +K G RKK + ++ R +KR+ R KK+R K+ K E
Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Score = 32.3 bits (72), Expect = 3.9
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 332 RTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKR-RGKKVKSEATTR 390
R RR+R+ R+R++ RK+ K + R K+R+ + K+R + +K + E R
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 391 SR 392
R
Sbjct: 96 KR 97
Score = 32.0 bits (71), Expect = 5.1
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 337 RKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIAR 395
RKRK RR+KK R+K + K R K+++ +K+R + K R R R
Sbjct: 133 RKRKKRRKKK---RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
Score = 31.6 bits (70), Expect = 6.6
Identities = 16/70 (22%), Positives = 33/70 (47%)
Query: 326 QRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKS 385
+R R + +++ R +K+ RKK G + K ++++ R K+RR +K +
Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101
Query: 386 EATTRSRIAR 395
+ R + R
Sbjct: 102 KKRERKQRGR 111
Score = 31.6 bits (70), Expect = 6.6
Identities = 16/61 (26%), Positives = 28/61 (45%)
Query: 332 RTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRS 391
R ++RK RR K+ RKK K + R KK++ + ++R K+ + +
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Query: 392 R 392
R
Sbjct: 139 R 139
Score = 31.6 bits (70), Expect = 6.6
Identities = 17/57 (29%), Positives = 26/57 (45%)
Query: 336 RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSR 392
R ++ R RK+ RKK + K R +KR+ R K+ R KK + R +
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181
Score = 31.6 bits (70), Expect = 6.6
Identities = 15/57 (26%), Positives = 31/57 (54%), Gaps = 4/57 (7%)
Query: 336 RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSR 392
+++RK R+R+K G+++ K + R KKR+ K+R+ ++ + E R +
Sbjct: 141 KKRRKERKREKERGKRER----KRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Score = 31.2 bits (69), Expect = 8.7
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 6/63 (9%)
Query: 336 RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATR------SKKRQHRVKKRRGKKVKSEATT 389
++KRK R R K RK+ K + R KKR+ + + RR +K K E
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
Query: 390 RSR 392
R R
Sbjct: 123 RER 125
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 78.2 bits (191), Expect = 6e-14
Identities = 170/714 (23%), Positives = 252/714 (35%), Gaps = 107/714 (14%)
Query: 962 VTVVEP---EAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRS 1018
V V EP EA + D+L +V + P + S ++ KK K K +R R+RS
Sbjct: 228 VKVKEPSVQEATSTSDIL-----KVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 1019 GTRSESRDRSSRSASPSVGEERPRRQRSKAKS-----RRSSSDRSSSRERAKRKKAKDKS 1073
+RS +R RS P RR RS+++S R S R S R R ++
Sbjct: 283 KSRSRTRSRSPSHTRPR------RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPP 336
Query: 1074 REHR-RGPWGHSRRTSRSRSGSPGSSSYEHYESRKKK--KRRSASRPRGRECSPTSSLER 1130
R R R P RR+S S SGS SSS S KK KR S+ + R SP++S R
Sbjct: 337 RHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR 396
Query: 1131 LCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHS 1190
R R A P + R S +P +R R+ R S + T
Sbjct: 397 -------------RRHRPSPPATP-PPKTRHSPTPQQSNRTRKSRVSVSPGR---TSGKV 439
Query: 1191 PERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVLEVAAE 1250
+ KG + SP+P +P + +L + E ++A AD + + +
Sbjct: 440 TKHKGTEKRESPSPAP--KPRKVEL-----SESEEDKGGKMAAADSVQQRR----QYRRQ 488
Query: 1251 CEPDDLDLDYGDSVE-----AGHVFDDFSSDAVFIQLDDMSSP-PSPESTDSSPERDFPL 1304
+ D S E HV + +SP P ++SP
Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548
Query: 1305 KPALPPA------SLAVAAIQREVSL--MHDEDPSQPP----PLPEGTQEPHLLR--PDA 1350
P+ PP S A +R PS PP P P P R P
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP 608
Query: 1351 AEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESE 1410
K S P SP RV + P++ S RS +L + S
Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR 668
Query: 1411 SSAPAEDRAP---RAPLHRPQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDT 1467
S+ A P +P RP+ P+ + +P VR+ S P + P T
Sbjct: 669 STREARSPQPNKRHSPSPRPRAPQTSS------SPPPVRRGASSSP----QRRQSPSPST 718
Query: 1468 DPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQFILQGSLPLVGCGAAQTLAPVPAALTPA 1527
P + S P + ++ P V + + + GS P PAA P
Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGS-------------PEPAAKKPP 765
Query: 1528 SEPASQATAASNSEEKTPAPRLAAEKTKKEEYMKKLHMQERAVEEVKLAIKPFYQKREVT 1587
+ P S + S S +PA + K+ + + + K K++
Sbjct: 766 A-PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKK--------KKKKD 816
Query: 1588 KEEYKDILRKAVQKICHSKSGEINPVKVANLVKAYVDKYRHMRRHKKPEAGEEP 1641
K+ KD K +K H K + A + A + ++P A EP
Sbjct: 817 KKHKKDKKHKKHKK--HKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Score = 72.8 bits (177), Expect = 3e-12
Identities = 128/584 (21%), Positives = 212/584 (36%), Gaps = 89/584 (15%)
Query: 1001 RKKAKRKRVSREH--GRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRS 1058
+++ K++++ +E + + RD+ + +S R +R+RS++ RR S RS
Sbjct: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESS------REKRERSRSPRRRKS--RS 179
Query: 1059 SSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPR 1118
S R +++ R H R P R ++SRS SP E + + P
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSP----RHRTKSRSPSPAPEKKEKTPELPEPSVK-VKEPS 234
Query: 1119 GRECSPTSSL------ERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAR 1172
+E + TS + E + K + + ++++ PR R + +SRS + R+
Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS-RTRSRSP 293
Query: 1173 EHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVA 1232
H RPR R + ++RS+SP R+ P+P + P R P R+P P
Sbjct: 294 SHTRPRRRHR-SRSRSYSPRRR-------PSPRRRPSPRRRTPPRRMP-------PPPRH 338
Query: 1233 TADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPE 1292
++P++ + S S +L +SPP
Sbjct: 339 RRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR-- 396
Query: 1293 STDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLRPDAAE 1352
R P PA PP + ++ + S P G H E
Sbjct: 397 ------RRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH----KGTE 446
Query: 1353 KAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQESESS 1412
K E+P SP P E S S + + A + V + R ++ + +S SS
Sbjct: 447 KRESP-SPAPKPRKVELSESEEDKGGKMAAADSVQQR------RQYRRQNQQSSSDSGSS 499
Query: 1413 APAEDRAP-----------RAPLHRPQK-----PREGAWDMEDVAPTGVRQVFSELPFPS 1456
+ +ED P R H P + PR+ ++ +P G R+ S P P+
Sbjct: 500 SSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK---RQKETSPRG-RRRRSPSPPPT 555
Query: 1457 HVLPEPGFPDTDPSQVYSPGLPPAPAQPSSIP----PCALVSQPTVQFILQGSLPLVGCG 1512
P P P + +P PP PS P P P +Q S P
Sbjct: 556 RRRRSPS-PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP----P 610
Query: 1513 AAQTLAPVPAALTPASEPASQATAASNSEEKTPAPRLAAEKTKK 1556
+T +P P P AS + +P P+ + K
Sbjct: 611 KRRTASPPP----PPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650
Score = 71.2 bits (173), Expect = 8e-12
Identities = 130/580 (22%), Positives = 194/580 (33%), Gaps = 56/580 (9%)
Query: 991 RSRSTSSSRSRKKAKRKRVSR-EHGRTRSGTRSESRDRSSRSASPSVG--EERPRRQRSK 1047
RSRS +SR + R+R S R RS +RS SRS SP+ E+ P
Sbjct: 168 RSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227
Query: 1048 AKSRRSS-SDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESR 1106
K + S + +S+ + K K + P +S++ P S S SR
Sbjct: 228 VKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSR 287
Query: 1107 KKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPS 1166
+ + S +RPR R S + S R +R S R R P R RRSRSP
Sbjct: 288 TRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR--RTPPRRMPPPPRHRRSRSPV 345
Query: 1167 SEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAH 1226
R S +RS SP +K R +SP P + L +
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP-------------PRKTRRLSPSA 392
Query: 1227 VSPEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMS 1286
P P PP + + + SV G + + + S
Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452
Query: 1287 SPPSPESTD-SSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHL 1345
P P + S E D K A + +R+ + S E + H+
Sbjct: 453 PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
Query: 1346 LRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWN 1405
+ + S +P+ ++ S R + P S P R R+
Sbjct: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP----SPPPTRRRRS-------- 560
Query: 1406 LQESESSAPAEDRAPRAPLHR---PQKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEP 1462
S + P R P P R PR + +P +++ +S P P P
Sbjct: 561 --PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP-IQRRYSPSPPPKRRTASP 617
Query: 1463 GFPDTDPSQVYSPGLPPAPAQPSSIPPCALVSQPTVQFI-------LQGSLPLVGCGAAQ 1515
P P + SP PP S PP S T + +GS P A+
Sbjct: 618 PPP---PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674
Query: 1516 --------TLAPVPAALTPASEPASQATAASNSEEKTPAP 1547
+ +P P A +S P AS+S ++ +P
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP 714
Score = 65.5 bits (158), Expect = 4e-10
Identities = 155/748 (20%), Positives = 256/748 (34%), Gaps = 97/748 (12%)
Query: 339 RKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTRSRIARTLG 398
R+ R R + P R+K+ S + S R +KR H R K +S + + +T
Sbjct: 163 REKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPE 222
Query: 399 LRRPVHSSCIPSVLKPVEPSLGLLRADIGAASLSLFGDPYELDPFDSEELSANPLSPLSA 458
L P PSV + S L P + + E+ P S +
Sbjct: 223 LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 459 KRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDLLGSILSGQSLLMLG 518
K R+ +RS SH RP SR R + P P P
Sbjct: 283 KSRSRTRSRSPSH---TRPRRRHRSRSRSYSPRRRPSPRRRPSP---------------- 323
Query: 519 SSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNRPQ 578
R + + P +R+ + R + S S ++ P P+
Sbjct: 324 -------RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPK 376
Query: 579 STGLSCQGRSRTPARTAGAPVRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNGTNKHT 638
T S ++R + +A P R P+ P + P + HSP +N+
Sbjct: 377 RTS-SPPRKTRRLSPSASPPRRRHRPSPP-----------ATPPPKTRHSPTPQQSNRTR 424
Query: 639 LPLASAA-SKISSRDSKPPCRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRRDAAP 697
S + + S + +K P P PR+ ++SE +D GG+ AA
Sbjct: 425 KSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSE-------SEEDKGGKMAAAD 477
Query: 698 AHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTGSSRPPAPSSHGS 757
+ Q + R ++ + G + +E E R + G G R +PS S
Sbjct: 478 SVQQRRQY------RRQNQQSSSDSGSSSSSEDERPKRSHVKNG-EVGRRRRHSPSRSAS 530
Query: 758 LAPLGPSRGKGVGSTFESFRI-NIPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLF 816
+P R K R + P S +P P +R +P P
Sbjct: 531 PSPR--KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
Query: 817 SIKKTKQLRSEV---YDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQ 873
++ + Y PS P +++P P+R P + R +S + P Q
Sbjct: 589 RSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK--RRVSHSPPPKQRSS 646
Query: 874 AVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRR 933
V S PS + +G+ + + +P + + R R
Sbjct: 647 PVTKRRS----------------PSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 934 P---SPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPS 990
P S P P GAS S T P + +AA+ +R S
Sbjct: 691 PQTSSSPPP--VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVS 748
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKS 1050
SRS S S + +++ S +S+S S + SP+V ++ +K+ +
Sbjct: 749 SSRSVSGSP-------EPAAKKPPAPPSPVQSQS---PSTNWSPAVPVKK-----AKSPT 793
Query: 1051 RRSSSDRSSSRERAKRKKAKDKSREHRR 1078
S R+S +E +KK K K ++H++
Sbjct: 794 PSPSPPRNSDQEGGGKKKKKKKDKKHKK 821
Score = 58.2 bits (139), Expect = 7e-08
Identities = 101/415 (24%), Positives = 146/415 (35%), Gaps = 78/415 (18%)
Query: 892 EPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTF 951
+PP SS K R ++ + R P+ + R P+ + + S
Sbjct: 373 KPPKRTSSPPRKTR-RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVS 431
Query: 952 FGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSR 1011
G VT E PSP A R VEL + + + +R++ R
Sbjct: 432 PGRTSGKVTKHKGTEKRESPSP----APKPRKVELSESEEDKGGKMAAADSVQQRRQYRR 487
Query: 1012 EHGRTRS--GTRSESRDRSSRSASPSVGEERPRRQ----RSKAKSRRSSSDRSSSRERAK 1065
++ ++ S G+ S S D + + GE RR+ RS + S R +S R R +
Sbjct: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR 547
Query: 1066 RKKAKDKSREHRR---GPWGHSRRTS-------------RSRSGSPGSSS---YEHYESR 1106
R + +R R P RRT R RS SP S Y
Sbjct: 548 RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPS 607
Query: 1107 KKKKRRSASRPRG--RECSPTSSLERLCRH---------------------KHQ------ 1137
KRR+AS P R SP+ +R H KH+
Sbjct: 608 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPS 667
Query: 1138 ---RERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTR-----SH 1189
RE +P+++ S + PR R + S SP R R + P TR S
Sbjct: 668 RSTREARSPQPNKRHSPS-PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Query: 1190 SPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPV 1244
+PE K + ASP+P + R+ + SPE A A K P PV
Sbjct: 727 TPEPKKIKKAASPSPQS---------VRRVSSSRSVSGSPEPA-AKKPPAPPSPV 771
Score = 48.9 bits (115), Expect = 4e-05
Identities = 124/551 (22%), Positives = 182/551 (33%), Gaps = 60/551 (10%)
Query: 331 PRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATTR 390
P+ P+ K + ++K K P S S TRS+ H +RR +S + +
Sbjct: 256 PKEPSPEKNSKKEKEK---EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH---RSRSRSY 309
Query: 391 SRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRADI---GAASLSLFGDPYELDPFDSEE 447
S R RRP P P P R+ + +S SL G S
Sbjct: 310 SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369
Query: 448 LSANPLSPLSAKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEPVPDLLGS 507
P S+ R R + + P R R P A P P P P
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRR-------HRPSPPATPPPKTRHSPTPQQSNR 422
Query: 508 ILSGQSLLMLG-SSDVIIHRDGSLSAKRAAPVSFQRNSGSLSRGEEGFKGCLQPRALPSG 566
+ + G +S + G+ + +P R LS EE KG A
Sbjct: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV-ELSESEED-KGGKMAAADSVQ 480
Query: 567 SPAQGPSGNRPQS--TGLSCQGRSRTPART-----AGAPVRLDLPAAPGAVQARNLSNGS 619
Q N+ S +G S P R+ R P+ + R +
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET 540
Query: 620 VPGFRQSHSPWFNGTNKHTLPLASAASKISSRDSKPPCRSVVPGPPLK---PAPRR---- 672
P R+ SP T + P + A R PP R P PP + P+PRR
Sbjct: 541 SPRGRRRRSPSPPPTRRRRSP-SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP 599
Query: 673 TDISELPRIPKIRRDDG---GGRRDAAPAHGQSIEI-----PSACISRLTGREGTGQPGR 724
P P RR +R A+P+ + P S +T R +
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
Query: 725 GTRAESEASS----RVPREPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINI 780
+ S + S R P+ H+ S RP AP + S P+ +G S+
Sbjct: 660 HRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV----RRGASSS-------- 707
Query: 781 PGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSS 840
P S + P + P K ++ +PSP S+++ RS P +P
Sbjct: 708 PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ-SVRRVSSSRSVSGSP-EPAAKKPP 765
Query: 841 APGSSPERSGP 851
AP S + P
Sbjct: 766 APPSPVQSQSP 776
Score = 33.5 bits (75), Expect = 1.7
Identities = 47/182 (25%), Positives = 72/182 (39%), Gaps = 20/182 (10%)
Query: 326 QRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKS 385
QR +P P KR+T P R+ +PS P + S + K+R V KRR + S
Sbjct: 601 QRRYSPSPPP--KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658
Query: 386 EATTRSRIAR-TLGLRRPVHSSCIPSVLKPVEPSLGLLRADI--GAASLSLFGDPYELDP 442
+ S +R T R P + +P P + GA+S P
Sbjct: 659 KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS-----SPQRR-- 711
Query: 443 FDSEELSANPLSPLS--AKRRALSRSALQSHQPVARPVSVGLSRRRLPAAVPEPDLEEEP 500
S S P+ +S + + + ++A S Q V R +S R + PEP ++ P
Sbjct: 712 -QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSSRSVSGSPEPAAKKPP 765
Query: 501 VP 502
P
Sbjct: 766 AP 767
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 77.0 bits (188), Expect = 1e-13
Identities = 94/324 (29%), Positives = 128/324 (39%), Gaps = 45/324 (13%)
Query: 879 TSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPPE 938
+S +S G +PEPP S A + R D++R +G + +
Sbjct: 721 SSAPADSERGPKPEPPGSGSPAPPRRR----RRAQDDSQRRSLPAEEGSSGKK------- 769
Query: 939 PWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSS 998
DE G S S G + + E PPS +A T R R RS+ +S
Sbjct: 770 --DEGGGGSSSQDHGGRKH--------KGELPPSSCQRRAGTKR--SSRSSHRSQPSSGD 817
Query: 999 RSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRS 1058
A R+ ++ S E S S S S R RS +S SSSD S
Sbjct: 818 EDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDAS 877
Query: 1059 SSRERAKRKKA------KDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRR 1112
S + R+++ D S RR HS+R+ S SS + K+ K
Sbjct: 878 SDQSCYSRQRSYSDDSYSDYSDRSRR----HSKRSHDSDDSDYASSKHRS----KRHKYS 929
Query: 1113 SASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPS--SEHR 1170
S+ CS + S R H RERS R R S + R R KRRSRS + S R
Sbjct: 930 SSDDDYSLSCSQSRSRSR----SHTRERSRSR-GRSRSSSCSRSRSKRRSRSTTAHSWQR 984
Query: 1171 AREHRRPRSRE-KWPQTRSHSPER 1193
+R + R RSR + P RS S +R
Sbjct: 985 SRSYSRDRSRSTRSPSQRSGSRKR 1008
Score = 60.8 bits (146), Expect = 1e-08
Identities = 153/718 (21%), Positives = 242/718 (33%), Gaps = 82/718 (11%)
Query: 729 ESEASSRVPREPGVHTGSSRPPAPSSHGSLAPLGPSR-GKGVGSTFESFRINIPGNMAHS 787
E S V E V + R AP+S + + L G GS E ++P S
Sbjct: 610 EPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERS 669
Query: 788 SQL-----------SSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSD--- 833
+ SS ++K + E+ KK K+ +++ P+D
Sbjct: 670 GKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSER 729
Query: 834 -----PTGSDSSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFG 888
P GS S AP R+ + ++ S+ + + + + + + G
Sbjct: 730 GPKPEPPGSGSPAPPRRRRRA------QDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
Query: 889 TEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQ-----GLAARLRRPSPPEPWDEE 943
+ + L PSS R A + + R +P+ + RL + SP + +EE
Sbjct: 784 RKHKGELPPSSCQ---RRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE 840
Query: 944 D----GASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSR 999
+ G+ S R + S D + + S S S R
Sbjct: 841 EEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR 900
Query: 1000 SRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSS 1059
SR+ +KR S + S RS+ SS S+ + R RS++ +R S R
Sbjct: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQ-SRSRSRSHTRERSRSRGR 959
Query: 1060 SRERA-KRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPR 1118
SR + R ++K +SR W SR SR RS S S S + SRK+ + R
Sbjct: 960 SRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPS-QRSGSRKRSWGHESPEER 1018
Query: 1119 --GRECSPTSSLERLCRHKHQRERSHERPDRKE-------SVAWPRDRRKR--RSRSPSS 1167
GR S + R + R E P +K+ P + R
Sbjct: 1019 HSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEG 1078
Query: 1168 EHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRL------PA 1221
+ + ++ + +S ERK +V E A + P +D P P+
Sbjct: 1079 DCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPS 1138
Query: 1222 LGEAHVSPEVATADKAPLQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVF-- 1279
LG V P + + P + +CE L+ SSDA+F
Sbjct: 1139 LGNKPVLPLIG-------KLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGH 1191
Query: 1280 -----IQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQPP 1334
+ PP ES D P+ P PA +S + DPS
Sbjct: 1192 QFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGD 1251
Query: 1335 PLPEGTQEPHLLRPDAAEKAEAPSSPDV-------APAGKEDSPSASGRVQEAARPEE 1385
L +P E + P +PD+ P+G S G + P E
Sbjct: 1252 TLESLDSSS---QPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLE 1306
Score = 35.4 bits (80), Expect = 0.46
Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 25/203 (12%)
Query: 1024 SRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGH 1083
SR++ +R+ G E+P+ S SS D + + K+K+ E
Sbjct: 579 SRNKDARTK----GTEKPKDIGS------SSKDHLQGLDPGEPNKSKEVGGEK------- 621
Query: 1084 SRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCR-HKHQRERSH 1142
R+S R +P S S ++++ S S S ER + H+H++++ H
Sbjct: 622 IVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKH 681
Query: 1143 ERPD---RKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVRE 1199
++ RK K S S + + R+ ++ +S R PE G+
Sbjct: 682 KKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGS--- 738
Query: 1200 ASPAPLAQGEPGREDLPTR-LPA 1221
SPAP + ++D R LPA
Sbjct: 739 GSPAPPRRRRRAQDDSQRRSLPA 761
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 76.6 bits (187), Expect = 2e-13
Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 26/183 (14%)
Query: 1021 RSESRDRSSRSASPSVGEERPRRQRSKAKSR-RSSSDRSSSRERAKRKKAKDKSREHRRG 1079
R+E DR R E++ R +R K + R R +R RE +R+K + + RE R+
Sbjct: 237 RTEEPDRDERLKK----EKQEREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 1080 PWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRE 1139
SR +SR+ S S S +H SR +++RRS SR R +R
Sbjct: 293 SRSRSRHSSRT-SDRRCSRSRDHKRSRSRERRRSRSRDR------------------RRS 333
Query: 1140 RSHERPDRKESVAWPRDRRKRRSRSPSS-EHRAREHRRPRSREKWPQTRSHSPERKGAVR 1198
RSH+R +RK + RDRR+ +SR S +HR++ R + R+ + + S ++K +V+
Sbjct: 334 RSHDRSERKHR-SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Query: 1199 EAS 1201
S
Sbjct: 393 SGS 395
Score = 59.7 bits (143), Expect = 2e-08
Identities = 57/190 (30%), Positives = 86/190 (45%), Gaps = 29/190 (15%)
Query: 982 RVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERP 1041
R+ + + R R R++ +RKR R E +R A +R
Sbjct: 246 RLKKEKQEREEREKEREREREERERKR------------RREEEEREKERA-----RDRE 288
Query: 1042 RRQRSKAKSRRSS--SDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSS 1099
RR+RS+++SR SS SDR SR R + + +SRE RR SR R RS S S
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHK---RSRSRERRR-----SRSRDRRRSRSHDRSE 340
Query: 1100 YEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESV-AWPRDRR 1158
+H SR + +RRS SR R + S +R K + + D+K SV + R+++
Sbjct: 341 RKH-RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
Query: 1159 KRRSRSPSSE 1168
+ + S E
Sbjct: 400 SEDTNTESKE 409
Score = 59.7 bits (143), Expect = 2e-08
Identities = 45/129 (34%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRS---SRSASPSVGEERPR---RQ 1044
RSRS S SR +R SR+H R+RS R SR R SRS S + R R R+
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
Query: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE 1104
RSK++ R+S RS SR+R + +K+K+K + G + S +SGS S +
Sbjct: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKR------GSDDKKSSVKSGSREKQSEDTNT 405
Query: 1105 SRKKKKRRS 1113
K+ ++
Sbjct: 406 ESKESDTKN 414
Score = 47.0 bits (110), Expect = 2e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 27/182 (14%)
Query: 1063 RAKRKKAKDKSREHRRGPWGHSR--RTSRSRSGSPGSSSYEHYESRKKKK---------- 1110
+A ++ K+K R+ P R + + R E E +K++
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
Query: 1111 -----RRSASRPRGRECSPTSSLERLCRHKHQRERSHER-----PDRKESVAWPRDRRKR 1160
RR SR R R S TS H+R RS ER DR+ S + R RK
Sbjct: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 1161 RSRS-----PSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDL 1215
RSRS S R R +SR++ +S E++G+ + S E ED
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 1216 PT 1217
T
Sbjct: 404 NT 405
Score = 36.6 bits (83), Expect = 0.21
Identities = 20/89 (22%), Positives = 40/89 (44%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R RS SRSR + + K R+ + RS +R +DR S+ +++ +S
Sbjct: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
Query: 1047 KAKSRRSSSDRSSSRERAKRKKAKDKSRE 1075
++ ++S + S+E + + S +
Sbjct: 394 GSREKQSEDTNTESKESDTKNEVNGTSED 422
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 76.6 bits (187), Expect = 2e-13
Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 26/183 (14%)
Query: 1021 RSESRDRSSRSASPSVGEERPRRQRSKAKSR-RSSSDRSSSRERAKRKKAKDKSREHRRG 1079
R+E DR R E++ R +R K + R R +R RE +R+K + + RE R+
Sbjct: 237 RTEEPDRDERLKK----EKQEREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 1080 PWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRE 1139
SR +SR+ S S S +H SR +++RRS SR R +R
Sbjct: 293 SRSRSRHSSRT-SDRRCSRSRDHKRSRSRERRRSRSRDR------------------RRS 333
Query: 1140 RSHERPDRKESVAWPRDRRKRRSRSPSS-EHRAREHRRPRSREKWPQTRSHSPERKGAVR 1198
RSH+R +RK + RDRR+ +SR S +HR++ R + R+ + + S ++K +V+
Sbjct: 334 RSHDRSERKHR-SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Query: 1199 EAS 1201
S
Sbjct: 393 SGS 395
Score = 59.7 bits (143), Expect = 2e-08
Identities = 57/190 (30%), Positives = 86/190 (45%), Gaps = 29/190 (15%)
Query: 982 RVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERP 1041
R+ + + R R R++ +RKR R E +R A +R
Sbjct: 246 RLKKEKQEREEREKEREREREERERKR------------RREEEEREKERA-----RDRE 288
Query: 1042 RRQRSKAKSRRSS--SDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSS 1099
RR+RS+++SR SS SDR SR R + + +SRE RR SR R RS S S
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHK---RSRSRERRR-----SRSRDRRRSRSHDRSE 340
Query: 1100 YEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESV-AWPRDRR 1158
+H SR + +RRS SR R + S +R K + + D+K SV + R+++
Sbjct: 341 RKH-RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
Query: 1159 KRRSRSPSSE 1168
+ + S E
Sbjct: 400 SEDTNTESKE 409
Score = 59.7 bits (143), Expect = 2e-08
Identities = 45/129 (34%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRS---SRSASPSVGEERPR---RQ 1044
RSRS S SR +R SR+H R+RS R SR R SRS S + R R R+
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
Query: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE 1104
RSK++ R+S RS SR+R + +K+K+K + G + S +SGS S +
Sbjct: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKR------GSDDKKSSVKSGSREKQSEDTNT 405
Query: 1105 SRKKKKRRS 1113
K+ ++
Sbjct: 406 ESKESDTKN 414
Score = 47.0 bits (110), Expect = 2e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 27/182 (14%)
Query: 1063 RAKRKKAKDKSREHRRGPWGHSR--RTSRSRSGSPGSSSYEHYESRKKKK---------- 1110
+A ++ K+K R+ P R + + R E E +K++
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
Query: 1111 -----RRSASRPRGRECSPTSSLERLCRHKHQRERSHER-----PDRKESVAWPRDRRKR 1160
RR SR R R S TS H+R RS ER DR+ S + R RK
Sbjct: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 1161 RSRS-----PSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDL 1215
RSRS S R R +SR++ +S E++G+ + S E ED
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 1216 PT 1217
T
Sbjct: 404 NT 405
Score = 36.6 bits (83), Expect = 0.21
Identities = 20/89 (22%), Positives = 40/89 (44%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R RS SRSR + + K R+ + RS +R +DR S+ +++ +S
Sbjct: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
Query: 1047 KAKSRRSSSDRSSSRERAKRKKAKDKSRE 1075
++ ++S + S+E + + S +
Sbjct: 394 GSREKQSEDTNTESKESDTKNEVNGTSED 422
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 74.7 bits (182), Expect = 7e-13
Identities = 69/264 (26%), Positives = 101/264 (38%), Gaps = 19/264 (7%)
Query: 987 RPPSRSRSTSSSRS----RKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPR 1042
R R R T R R++A + R+ R R R RDR + +R R
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 1043 R-QRSKAKSRRSSSDRSSSRERAK-RKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSY 1100
R +R + R+ R RER + RK+ +++ RE R R T R R
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERE---RQRETERDRE-----KER 341
Query: 1101 EHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKR 1160
E R+ + R +R GRE + ER + R+ + ER +R+ RDR+K
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR--DRDRQKE 399
Query: 1161 RSRSPSSEHRA-REHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRL 1219
R R + RE + R REK S +G RE E + R
Sbjct: 400 RERQTEKDRDGQRETEKQREREK--DRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
Query: 1220 PALGEAHVSPEVATADKAPLQAPP 1243
+V+P TA +Q+ P
Sbjct: 458 RKRSTLYVNPPPRTARSGVVQSDP 481
Score = 73.2 bits (178), Expect = 2e-12
Identities = 56/224 (25%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPR-RQRSKAK 1049
R R T R R+ + ++ RE + R R R R + + ER R R+R +
Sbjct: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
Query: 1050 SRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKK 1109
+ R + RER +++K + + + R T R + + R+K+
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 1110 KRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEH 1169
+ R R R R ER + +RER ER ++E R+R + R R +E
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER---ERERERERERQRETE- 334
Query: 1170 RAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGRE 1213
R RE R R R++ QT + RE + E RE
Sbjct: 335 RDREKERERKRKR--QTEMDRERNRQTGREGRRQAERERERERE 376
Score = 69.7 bits (169), Expect = 2e-11
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 10/212 (4%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRS----GTRSESRDRSS-RSASPSVGEERPRR-Q 1044
R R R+R+K + + RE R R G R R R + + ER R+ +
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 1045 RSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSR-SRSGSPGSSSYEHY 1103
R++ K R +R RER +R++ K+ E R G R R + + + +
Sbjct: 173 RNRQKEREREKNRQERRER-ERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 1104 ESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDR-RKRRS 1162
R++K R + RE + ER + +R+R +R R++ DR R+RR+
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 1163 RSPSSEHRAREHRRPRSREKWPQTRSHSPERK 1194
R RE +R R RE+ + R ER+
Sbjct: 292 ERDRETERKRERQRERERER-ERNRKRERERE 322
Score = 66.6 bits (161), Expect = 2e-10
Identities = 57/235 (24%), Positives = 87/235 (37%), Gaps = 11/235 (4%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R R R + R+R+K + + +R+ R R R + R + ER R +
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 1047 KAKSRRSSS---DRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHY 1103
+ + +R + DR ER + K+A+ + R R R R E
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 1104 ESRKKKKRRSASR----PRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRK 1159
+K++R R R RE ER K +RER ER +R+ RDR K
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER-ERERQRETERDREK 339
Query: 1160 RRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGRED 1214
R R R E R R+R+ + R + + RE + E D
Sbjct: 340 ERER---KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Score = 65.9 bits (159), Expect = 3e-10
Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 8/211 (3%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R R R R R + + ++ RE R R R R R E R+
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 1047 KAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESR 1106
+ + R++ R R+R K+ + ++ R+ +R+ R R + +
Sbjct: 137 RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
Query: 1107 KKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPS 1166
K+ K RGRE E K Q +R +R + E R+R K+ R +
Sbjct: 197 KENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTE-----REREKQAERERA 251
Query: 1167 SEH---RAREHRRPRSREKWPQTRSHSPERK 1194
SE R +E R R R++ R ER+
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQ 282
Score = 65.1 bits (157), Expect = 5e-10
Identities = 52/208 (25%), Positives = 82/208 (39%), Gaps = 22/208 (10%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRS 1046
R R R T R R++ K + +E R RDR + G+ RQR
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD------GQRERERQRD 154
Query: 1047 KAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESR 1106
K R +DR R+ +R + K++ RE R R R R + + + + R
Sbjct: 155 AEKERERQTDRERQRQ-TERNRQKEREREKNR-----QERRERERQREKENKTEDRHSER 208
Query: 1107 KKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPS 1166
+++ R RE + +R + R+R ER K++ R+R R
Sbjct: 209 GRERERE------RETETETERKRQTDRERDRQRKTEREREKQA---ERERASERETERD 259
Query: 1167 SEHRAREHRRPRSREKWPQTRSHSPERK 1194
E R RE R R R++ + R +RK
Sbjct: 260 KE-RERERDRDRDRDRRQKERERQTDRK 286
Score = 65.1 bits (157), Expect = 5e-10
Identities = 53/241 (21%), Positives = 93/241 (38%), Gaps = 25/241 (10%)
Query: 990 SRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAK 1049
+++ S R R++ + + E R R R R R + E +R +
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 1050 SRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGS---PGSSSYEHYESR 1106
+ +R R+R +R+K +++ + +R RRT R R E R
Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKR-----QRRTERDRETERKRERQRERERERER 313
Query: 1107 KKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHE----------RPDRKESVAWPRD 1156
+K+ R R R RE + +R + +R+R E R R+++ R+
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA---ERE 370
Query: 1157 RRKRRSRSPSS----EHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGR 1212
R + R R S E R R+ R R +E+ QT ++ ++ + E GR
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430
Query: 1213 E 1213
E
Sbjct: 431 E 431
Score = 65.1 bits (157), Expect = 5e-10
Identities = 59/210 (28%), Positives = 86/210 (40%), Gaps = 23/210 (10%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSS---RSASPSVGEERPRR 1043
R R R+ R R++ + + RE R R R R R + R + G E RR
Sbjct: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG-RR 365
Query: 1044 QRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHY 1103
Q + + R DR S+RER +R++ +D+ R+ R R+T + R G + E
Sbjct: 366 QAERERERERERDRQSAREREERERDRDRDRQKER-----ERQTEKDRDGQRET---EKQ 417
Query: 1104 ESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERP---DRKESVAW--PRDRR 1158
R+K + R RGRE ER RER +R RK S + P R
Sbjct: 418 REREKDRESERGRERGREREKQKGRER------DRERQTDRQAGRQRKRSTLYVNPPPRT 471
Query: 1159 KRRSRSPSSEHRAREHRRPRSREKWPQTRS 1188
R S +R R +S + P+ S
Sbjct: 472 ARSGVVQSDPNRPTRGIRWKSSPEDPKAAS 501
Score = 63.9 bits (154), Expect = 1e-09
Identities = 47/216 (21%), Positives = 87/216 (40%), Gaps = 10/216 (4%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSV-GEERP---R 1042
R R R R R+K + ++ RE R R R+ ++R + G +R +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 1043 RQRSKAKSRRSSSDRSSSRER---AKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSS 1099
R+R + + +R + RER +R + K++ RE R R R +
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE-RRERERQREKENKTEDRH 205
Query: 1100 YEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRK 1159
E R++++ R R+ +R + +++ ER +E+ ++R +
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER-DKERER 264
Query: 1160 RRSRSPSSEHRAREHRRPRSREKWPQT-RSHSPERK 1194
R R + R +E R R++ +T R ERK
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
Score = 62.4 bits (150), Expect = 4e-09
Identities = 59/233 (25%), Positives = 83/233 (35%), Gaps = 33/233 (14%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKS 1050
R R+ R R++ KR+ RE R R R + R R + RQR + K
Sbjct: 54 RERNRQKERERRREKRQ-TERETDRKRERRREKDRHRKR--------DRHRERQRDREKE 104
Query: 1051 RRSSSDRSSSRERAKRKKAKDKSRE---------HRRGPWGHSRRTSRSRSGSPGSSSYE 1101
R +DR R+R +K R R G G R+T G E
Sbjct: 105 RERQTDRERDRQR-------EKERNRQKERERETEREGERGRDRQTD-------GQRERE 150
Query: 1102 HYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRR 1161
+K++ R R R R+ ER Q R ER KE+ R + R
Sbjct: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
Query: 1162 SRSPSSEHRAR-EHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGRE 1213
R E E +R RE+ Q ++ K A RE + + + RE
Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Score = 58.9 bits (141), Expect = 4e-08
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 14/197 (7%)
Query: 1006 RKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAK 1065
R+R + R G +D + +ER RR+ + R + R RE+ +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 1066 RKKAKDKSREHRRG-PWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASR--PRGREC 1122
+K +D+ RE +R R+T R R E +R+K++ R R RGR+
Sbjct: 88 HRK-RDRHRERQRDREKERERQTDRER-----DRQREKERNRQKERERETEREGERGRDR 141
Query: 1123 SPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREK 1182
ER + ++ER + DR+ R+R+K R R ++R R R REK
Sbjct: 142 QTDGQRERERQRDAEKERERQ-TDRERQRQTERNRQKERER---EKNRQERRERERQREK 197
Query: 1183 WPQTRSHSPERKGAVRE 1199
+T ER G RE
Sbjct: 198 ENKTEDRHSER-GRERE 213
Score = 35.0 bits (79), Expect = 0.60
Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 12/151 (7%)
Query: 1050 SRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKK 1109
SRR + S R R + KD + R +R+ R R + E +K
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRE----RNRQKERERRREKRQTERE----TDRK 78
Query: 1110 KRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSE- 1168
+ R + R R+ +R + +R+ ER ++E R+R+K R R E
Sbjct: 79 RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREK---ERNRQKERERETEREG 135
Query: 1169 HRAREHRRPRSREKWPQTRSHSPERKGAVRE 1199
R R+ + RE+ Q + + RE
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRE 166
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 74.7 bits (182), Expect = 7e-13
Identities = 99/352 (28%), Positives = 141/352 (40%), Gaps = 50/352 (14%)
Query: 1014 GRTRSGTRSESRDRSS-----RSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKK 1068
GR S T ESR + RS+S S + R ++ + RS S RS SR+ R
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKS-RSWSRDLQPRSH 60
Query: 1069 AKDKSREHR---RGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPT 1125
+ D+ R HR +G R+ SRSRS G S K + RRS SRPR R
Sbjct: 61 SYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRS---- 116
Query: 1126 SSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQ 1185
H ERS R R S RDR +R+ R E R +E + + +E
Sbjct: 117 --------HSRSSERSSHRRTRSRS----RDRERRKGR--DKEKREKEKDKGKDKELHNI 162
Query: 1186 TRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAPPVL 1245
R S K + PA E RL + EA A AD+A L+A
Sbjct: 163 KRGESGNIKAGLEHLPPA---------EQAKARLQLVLEA-----AAKADEA-LKAKERN 207
Query: 1246 EVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLK 1305
E A+ ++ + V+ + SD+ F+Q SS +S + S +K
Sbjct: 208 EEEAKRRKEEDQATLVEQVKRVKEIEAIESDS-FVQQTFRSSKEVKKSVEPS-----EVK 261
Query: 1306 PALPPASLAVAAIQREVSLMHDEDPSQPPPLPEGTQEPHLLRPDA-AEKAEA 1356
A + A +A+ S + DP+ P + + L P+ EKA+A
Sbjct: 262 QATSTSGPA-SAVADPPSTEKEIDPTSIPTAIKYQDDNSLAHPNLFIEKADA 312
Score = 62.4 bits (150), Expect = 4e-09
Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRS-GTRSESRDRSSRSASPSVGEERPRRQR 1045
R S S S S + SRKK RK S+ +R RS S DR R S S RR+R
Sbjct: 23 RSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHRSSSSSSYGSRRKR 82
Query: 1046 SKAKSR-RSSS---DRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101
S+++SR R S RS S+ R +R +++ + R H R S R +RSRS
Sbjct: 83 SRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGR 142
Query: 1102 HYESRKKKKRRSASR-----PRGRECSPTSSLERLCRHKHQRERSH---ERPDRKESVAW 1153
E R+K+K + + RG + + LE L + + R E + +
Sbjct: 143 DKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALK 202
Query: 1154 PRDRRKRRSRSPSSEHRA 1171
++R + ++ E +A
Sbjct: 203 AKERNEEEAKRRKEEDQA 220
Score = 57.0 bits (136), Expect = 1e-07
Identities = 66/251 (26%), Positives = 105/251 (41%), Gaps = 22/251 (8%)
Query: 976 LQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPS 1035
LQ +H + R RS S+SS SR+K R R SR G++ RS S+ R+ RS S
Sbjct: 55 LQPRSHSY-DRRRRHRSSSSSSYGSRRKRSRSR-SRGRGKSYRVQRSRSKSRTRRSRS-- 110
Query: 1036 VGEERPRRQRSKAKSRRSSSDRSSSRER-AKRKKAKDKSREHRRGPWGHSRRTSRSRSGS 1094
RPR + S RSS R+ SR R +R+K +DK + + G + + G
Sbjct: 111 ----RPRLRSHSRSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGE 166
Query: 1095 PGS--SSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVA 1152
G+ + EH ++ K R + + E L + E + R + ++
Sbjct: 167 SGNIKAGLEHLPPAEQAKARLQLVLE----AAAKADEALKAKERNEEEAKRRKEEDQATL 222
Query: 1153 WPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSP-ERKGAVREASPAPLAQGEPG 1211
+ +R + + S+ ++ R K +S P E K A + PA P
Sbjct: 223 VEQVKRVKEIEAIESDSFVQQTFRSSKEVK----KSVEPSEVKQATSTSGPASAVADPPS 278
Query: 1212 --REDLPTRLP 1220
+E PT +P
Sbjct: 279 TEKEIDPTSIP 289
Score = 56.6 bits (135), Expect = 2e-07
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 17/162 (10%)
Query: 990 SRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRS-SRSASP-SVGEERPRRQRSK 1047
SRS+ R R + SR + R + G +S S+ RS SR P S +R RR RS
Sbjct: 12 SRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHRS- 70
Query: 1048 AKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRK 1107
SSS SR + R +++ + + +R RT RSRS S E
Sbjct: 71 -----SSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSS 125
Query: 1108 KKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKE 1149
++ RS SR R R R R K +RE+ ++ KE
Sbjct: 126 HRRTRSRSRDRER---------RKGRDKEKREKEKDKGKDKE 158
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 74.3 bits (181), Expect = 9e-13
Identities = 68/233 (29%), Positives = 97/233 (41%), Gaps = 33/233 (14%)
Query: 985 ELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRS-SRSASPSVGEERPRR 1043
E R SRSRS S R + R R SR R RS ++S SR RS S S ER RR
Sbjct: 244 EKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRR 303
Query: 1044 QRSKAKSRRSSSDRSSSRERAKRKKA--KDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101
RS +K+R D+ + KR K K S R RR RSRSG
Sbjct: 304 SRSTSKTR----DKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG-------- 351
Query: 1102 HYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRR 1161
+R KK RS R R SP RHK ++++ ++ ++ R+R +
Sbjct: 352 ---TRSPKKPRSPKRKLSRSPSPR-------RHKKEKKKDKDKERSRDE----RERSTSK 397
Query: 1162 SRSPSSEHRAREHRRPRSREKWPQTRSHSPERKG----AVREASPAPLAQGEP 1210
+ + + RE + ++ TR + E +G ++ P+ G P
Sbjct: 398 KKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSP 450
Score = 66.6 bits (161), Expect = 2e-10
Identities = 65/222 (29%), Positives = 100/222 (45%), Gaps = 31/222 (13%)
Query: 981 HRVVELRPPSRSRSTSSSRSRKKAKRKRVSREH-GRTRSGTRSESRDRSSRSASPSVGEE 1039
H L PS TSS + KR R ++ + E + R SRS S S
Sbjct: 200 HVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRS---- 255
Query: 1040 RPRRQRSKAKSRRS---SSDRSSSRERAKRK-KAKDKSREHRRGPWGHSRRTSRSRSGSP 1095
R RR S ++ RRS S RS S+ R++R+ K+ + R H R SR TS++R
Sbjct: 256 RRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRD--- 312
Query: 1096 GSSSYEHYESRKKKKRRSASRPRGREC---SPTSSLERLCRHKHQRERSHERPDRKESVA 1152
+ K+K+RS + P+ S ++S ER + +R RS R +K
Sbjct: 313 -------KKKEDKEKKRSKTPPKSYSTARRSRSASRER----RRRRSRSGTRSPKK---- 357
Query: 1153 WPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERK 1194
PR +++ SRSPS +E ++ + +E+ R S +K
Sbjct: 358 -PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK 398
Score = 40.0 bits (92), Expect = 0.019
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 332 RTPARRKRKTRRRKKVPGRKKTPSGPSAKSK--SSATRSKKRQHRVKKRRGKKVKSEATT 389
R + K ++RRR K P R+++ S + +S TR KK++ + KKR KS +T
Sbjct: 274 RRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTA 333
Query: 390 RSRIARTLGLRRPVHSSCIPSVLKPVEPSLGLLRA 424
R + + RR S S KP P L R+
Sbjct: 334 RRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRS 368
Score = 35.8 bits (81), Expect = 0.35
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 1/128 (0%)
Query: 258 PTTSRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVA 317
P++SR R R+R + ++ R R+ R R S +R + R S D+ E
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE-RGRRSRSTSKTRDKKKEDKE 319
Query: 318 TGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKK 377
S + T R R+ RRR+ G + S K K S + S +R + KK
Sbjct: 320 KKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
Query: 378 RRGKKVKS 385
+ K +S
Sbjct: 380 KDKDKERS 387
Score = 33.9 bits (76), Expect = 1.3
Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 8/116 (6%)
Query: 987 RPPSRSRSTSSS-RSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQR 1045
R P R S S S R KK K+K +E R + R+RS+ S +E+ R ++
Sbjct: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSR-------DERERSTSKKKKSKDKEKDRERK 411
Query: 1046 SKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101
S++ R E K+K E + G + S G S E
Sbjct: 412 SESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRE 467
Score = 32.3 bits (72), Expect = 3.9
Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 9/128 (7%)
Query: 261 SRLRPRAGRTRAIARTRQSERVRATVNRNRISTARRVQHTPGRLGSSLLDEAIEAVATGL 320
S R R R+R+ ++TR ++ + + R T + T R S+ + +G
Sbjct: 295 SHSRERGRRSRSTSKTR--DKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT 352
Query: 321 STAVYQRPLTPRTPARR--KRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVKKR 378
+ P PR+P R+ + + RR K +K S + +T KK+ +K
Sbjct: 353 RS-----PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
Query: 379 RGKKVKSE 386
R +K +S+
Sbjct: 408 RERKSESD 415
Score = 32.0 bits (71), Expect = 5.1
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 306 SSLLDEAIEAVATGLSTAVYQRPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSA 365
S ++EA++ V S + + P ++R +R R + R++TPS S++ + S
Sbjct: 216 SKEIEEAMKRVREAQS--LISAAIEPDKKEEKRRHSRSRSR-SRRRRTPS--SSRHRRSR 270
Query: 366 TRSKKRQHRVKKRRGKKVKSEATTRS 391
+RS++R H K R ++ KS RS
Sbjct: 271 SRSRRRSHS-KSRSRRRSKSPRRRRS 295
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens]
Length = 1031
Score = 73.2 bits (178), Expect = 2e-12
Identities = 59/207 (28%), Positives = 88/207 (42%), Gaps = 25/207 (12%)
Query: 991 RSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKS 1050
R RS S RS +++ + S + + RS SRDR R R+RS+++
Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRR------------RERSRSRD 56
Query: 1051 RRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKK 1110
+R S R R R R + +D+SRE RR SR RSRS S G S K KK
Sbjct: 57 KRRSRSRDRKRLRRSRSRERDRSRERRR---SRSRDRRRSRSRSRGRRSRSSSPGNKSKK 113
Query: 1111 RRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHR 1170
+ SR + + SS K +++ ++ D KE A D+ K + R
Sbjct: 114 TENRSRSKEKTDGGESS-------KEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKER 166
Query: 1171 A---REHRRPRSREKWPQTRSHSPERK 1194
RE +R ++ E + + E K
Sbjct: 167 VEKWREEQRKKAMENIGELKKEIEEMK 193
Score = 64.7 bits (156), Expect = 7e-10
Identities = 60/187 (32%), Positives = 86/187 (45%), Gaps = 13/187 (6%)
Query: 1023 ESRDRSSRSASPSVGEERPR-RQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPW 1081
ESR RSAS R R R S +S+R RS SR+R +R++ + +SR+ RR
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRE-RSRSRDKRRSRS 62
Query: 1082 GHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERS 1141
+R RSRS S E SR + +RRS SR RGR S +SS + R RS
Sbjct: 63 RDRKRLRRSRS-RERDRSRERRRSRSRDRRRSRSRSRGRR-SRSSSPGNKSKKTENRSRS 120
Query: 1142 HERPDRKESVAW------PRDRRKRRSRSPSSEHRAREHRRPRSR--EKW-PQTRSHSPE 1192
E+ D ES ++ K + +++ E R R EKW + R + E
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180
Query: 1193 RKGAVRE 1199
G +++
Sbjct: 181 NIGELKK 187
Score = 48.9 bits (115), Expect = 4e-05
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 8/116 (6%)
Query: 1102 HYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRR 1161
HY R + RS SR R SP+ +R R +R RS +R DR+ + RD+R+ R
Sbjct: 7 HYRKRSASRGRSGSR--SRSRSPSD--KRSKRGDDRRSRSRDR-DRRRERSRSRDKRRSR 61
Query: 1162 SRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPT 1217
SR R+R R RSRE+ RS S +R+ + + PG + T
Sbjct: 62 SRDRKRLRRSRSRERDRSRER---RRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKT 114
Score = 43.9 bits (102), Expect = 0.001
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 16/127 (12%)
Query: 982 RVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERP 1041
R+ R R RS RSR + +R+ +RS SR R SRS+SP +
Sbjct: 67 RLRRSRSRERDRSRERRRSRSRDRRR------------SRSRSRGRRSRSSSPG---NKS 111
Query: 1042 RRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101
++ ++++S+ + SS+E+ K K K+ +E G + ++ R +
Sbjct: 112 KKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWR 171
Query: 1102 HYESRKK 1108
E RKK
Sbjct: 172 E-EQRKK 177
Score = 38.1 bits (87), Expect = 0.071
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 1130 RLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSH 1189
R RH +R S R + P D+R +R S R R+ RR RSR + + RS
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSR-DKRRSR 61
Query: 1190 SPERKGAVREAS 1201
S +RK R S
Sbjct: 62 SRDRKRLRRSRS 73
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 72.8 bits (177), Expect = 3e-12
Identities = 31/63 (49%), Positives = 38/63 (60%)
Query: 170 PVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPE 229
P +K + D C +CG + EDRLLLCDGCD YH CL PPL +VP +W CP+
Sbjct: 296 PKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK 355
Query: 230 CAA 232
C A
Sbjct: 356 CLA 358
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 72.8 bits (177), Expect = 3e-12
Identities = 31/63 (49%), Positives = 38/63 (60%)
Query: 170 PVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPE 229
P +K + D C +CG + EDRLLLCDGCD YH CL PPL +VP +W CP+
Sbjct: 296 PKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK 355
Query: 230 CAA 232
C A
Sbjct: 356 CLA 358
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 72.8 bits (177), Expect = 3e-12
Identities = 106/439 (24%), Positives = 166/439 (37%), Gaps = 64/439 (14%)
Query: 747 SRPPAPSSHGS------LAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFR 800
S P PS G A +G G G S + G + +S F
Sbjct: 528 SAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKAS----------FA 577
Query: 801 PVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITR 860
P+ + KEN L ++K R ++ D SD + S G S P+
Sbjct: 578 PISFAIKAKEND--LLPLEKN---RVKLDDDSDD--DEESKEGQESSSSAANTNPAVAPP 630
Query: 861 TISINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREE 920
+ + K Q +T +E+ + ++A KL A + E
Sbjct: 631 CVVVEEKKPQ-------LTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAER 683
Query: 921 PTESQGLAARLRRPSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQAAT 980
++ L+ P P + E G + F EE + T P P +
Sbjct: 684 KRKAALFLQTLKNPLP----EAEAGKIEESPFSVEESSTT----------PCPLLTGGRP 729
Query: 981 HRVVELRPPSR--SRSTSSSRSRKKAKRKRVSREHGRTRS-----GTRSESRDRSSRSAS 1033
+E++PP R S+S R +K K+K+ ++ RTRS + S+SR RS A
Sbjct: 730 LPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAK 789
Query: 1034 PSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSG 1093
S+ +RS+++S RS R+ S ER + +++ + R P G SR+ +RSRS
Sbjct: 790 HSLPSAYRTVRRSRSRS-RSPRRRAHSPERRREERSVPTAYRVSRSP-GASRKRTRSRS- 846
Query: 1094 SPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAW 1153
KKKKRRS SR + + S + S + + +H S
Sbjct: 847 ----------PHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVE 896
Query: 1154 PRDRRKRRSRSPSSEHRAR 1172
R + RSR S E A+
Sbjct: 897 SRGSSQERSRGVSQEKEAQ 915
Score = 65.5 bits (158), Expect = 4e-10
Identities = 66/238 (27%), Positives = 100/238 (42%), Gaps = 28/238 (11%)
Query: 978 AATHRVVELRPPSRSRSTSSSRSRKKA------KRKRVSREHGRTRSGTRSESRDRSSRS 1031
AA ++ + S+ + + R RK A K E G+ S + SS +
Sbjct: 662 AAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSV--EESSTT 719
Query: 1032 ASPSVGEERPR-----RQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRR 1086
P + RP + + S+ R +E+ K+KK K +SR R P HS
Sbjct: 720 PCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEK-KKKKHKKRSRTRSRSPKYHSSS 778
Query: 1087 TSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPD 1146
SRSRS S S ++ R + PR R SP + +RE
Sbjct: 779 KSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSP----------ERRREERSVPTA 828
Query: 1147 RKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREK-WPQTRSHSPERKGAVREASPA 1203
+ S + R++ RSRSP H ++ RR RSR K +++S SP ++ A R A+PA
Sbjct: 829 YRVSRSPGASRKRTRSRSP---HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPA 883
Score = 43.9 bits (102), Expect = 0.001
Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 1116 RPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRA-REH 1174
RP + P E+ + K ++RS R + + + R + S++ S A R
Sbjct: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799
Query: 1175 RRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTR 1218
RR RSR + P+ R+HSPER+ R A PG TR
Sbjct: 800 RRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTR 843
Score = 37.7 bits (86), Expect = 0.093
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 327 RPLTPRTPARRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRS---KKRQHRVKKRRGKKV 383
R +PR A + R + VP + P A K + +RS KK++ R + R K
Sbjct: 805 RSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKA 864
Query: 384 KSEATTRSRIARTLGLRRPVHSSCIPSVLKPVE 416
+S++ + S+ A HS+ SV PVE
Sbjct: 865 RSQSVSPSKQAAPRPAAPAAHSAHSASV-SPVE 896
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 72.8 bits (177), Expect = 3e-12
Identities = 119/452 (26%), Positives = 160/452 (35%), Gaps = 98/452 (21%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERP----- 1041
R P R R +SS RS+++ REH R R G R S SRS GEER
Sbjct: 196 RRPRRDRRSSSGRSKER------HREH-RRRDGQRGGSEASKSRSRHSHSGEERAEVAKS 248
Query: 1042 --------RRQRSKAKSRRSSS--DRSSSRERAKRKKAKDKS----------REHRRGPW 1081
RR+ + A S SSS DR S R++ K +K+ RE + P
Sbjct: 249 GSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPK 308
Query: 1082 GHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSP--------TSSLERLCR 1133
+ RR S S G S H S+ + R+S S P G SP S R
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS-PAGGGSSPYSRRLPRSPSPYSRRRS 367
Query: 1134 HKHQRERSHER-----PDRKESVAWPRDRR----------KRRSRSPSSEHRAR---EHR 1175
+ R S+ER P S +W R R K RSRSP S +R HR
Sbjct: 368 PSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHR 427
Query: 1176 RPRSREKW----PQT------------RSHSPERKGAVREASPAPLAQGEPGREDLP--- 1216
RSR + P T ++ A R A A A+ E
Sbjct: 428 LSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAA 487
Query: 1217 ----TRLPALGEAHVSP------EVATADKAPLQAPPVLEVAAECEPDDLDLD---YGDS 1263
T P G S V K ++ P + D
Sbjct: 488 KASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTK 547
Query: 1264 VEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVS 1323
VE + D + AV + + S+ ES S E+ PL P S+ ++ V+
Sbjct: 548 VENNLIVDKATKKAVIVGKESKSAATKEESV-SLKEKTKPLTP-----SIGAKEKEQHVA 601
Query: 1324 LMHDEDPSQP-PPLPEGTQEPHLLRPDAAEKA 1354
L+ P P PP+ +E LR + + KA
Sbjct: 602 LVTSTLPPLPLPPMLPEDKEADSLRGNISVKA 633
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/198 (25%), Positives = 78/198 (39%), Gaps = 23/198 (11%)
Query: 1019 GTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKK-----AKDKS 1073
GT +S S + GE RR R + RRSSS RS R R R++ + S
Sbjct: 173 GTGGSGGSPASSSGTQRRGEGSERRPR---RDRRSSSGRSKERHREHRRRDGQRGGSEAS 229
Query: 1074 REHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCR 1133
+ R R ++SGS SS R+K ++S R+ + + +
Sbjct: 230 KSRSRHSHSGEERAEVAKSGSSSSSG-----GRRKSASATSSSSSSRKDRDSKAHRSRTK 284
Query: 1134 HKHQRERSHERPDR--KESVAWPRDRRKRRSRSPSS-------EHRAREHRRPRSREKWP 1184
+ +++ P + +E P+ R+RRS SP HRA + R R + P
Sbjct: 285 SSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSR-KSPSP 343
Query: 1185 QTRSHSPERKGAVREASP 1202
SP + R SP
Sbjct: 344 AGGGSSPYSRRLPRSPSP 361
Score = 36.6 bits (83), Expect = 0.21
Identities = 48/202 (23%), Positives = 79/202 (39%), Gaps = 15/202 (7%)
Query: 918 REEPTESQGLAARLRR--PSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDV 975
R+ P+ + G ++ R P P P+ S S S ER V P S
Sbjct: 338 RKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRH-SSYERGGD----VSPSPYSSSSW 392
Query: 976 LQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPS 1035
++ + LR +SRS S SR R R H +RS +R S S+ + S
Sbjct: 393 RRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSR----HRLSRSRSRHSSISPSTLTLKSS 448
Query: 1036 VGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSP 1095
+ E + ++++A +++ + + E K +A K+ + S T + S
Sbjct: 449 LAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKAS----NTSTPTKGNTETSA 504
Query: 1096 GSSSYEHYESRKKKKRRSASRP 1117
+S H + KK K A P
Sbjct: 505 SASQTNHVKDVKKIKIEHAPSP 526
Score = 32.3 bits (72), Expect = 3.9
Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 7/100 (7%)
Query: 319 GLSTAVYQRPLTPRTPA--RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVK 376
G ++ Y R L PR+P+ R+R + + PS S SS RS+ V
Sbjct: 345 GGGSSPYSRRL-PRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVL 403
Query: 377 KRRGKKVK----SEATTRSRIARTLGLRRPVHSSCIPSVL 412
+R GK S +RSR L R HSS PS L
Sbjct: 404 RRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTL 443
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 72.8 bits (177), Expect = 3e-12
Identities = 119/452 (26%), Positives = 160/452 (35%), Gaps = 98/452 (21%)
Query: 987 RPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERP----- 1041
R P R R +SS RS+++ REH R R G R S SRS GEER
Sbjct: 196 RRPRRDRRSSSGRSKER------HREH-RRRDGQRGGSEASKSRSRHSHSGEERAEVAKS 248
Query: 1042 --------RRQRSKAKSRRSSS--DRSSSRERAKRKKAKDKS----------REHRRGPW 1081
RR+ + A S SSS DR S R++ K +K+ RE + P
Sbjct: 249 GSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPK 308
Query: 1082 GHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSP--------TSSLERLCR 1133
+ RR S S G S H S+ + R+S S P G SP S R
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS-PAGGGSSPYSRRLPRSPSPYSRRRS 367
Query: 1134 HKHQRERSHER-----PDRKESVAWPRDRR----------KRRSRSPSSEHRAR---EHR 1175
+ R S+ER P S +W R R K RSRSP S +R HR
Sbjct: 368 PSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHR 427
Query: 1176 RPRSREKW----PQT------------RSHSPERKGAVREASPAPLAQGEPGREDLP--- 1216
RSR + P T ++ A R A A A+ E
Sbjct: 428 LSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAA 487
Query: 1217 ----TRLPALGEAHVSP------EVATADKAPLQAPPVLEVAAECEPDDLDLD---YGDS 1263
T P G S V K ++ P + D
Sbjct: 488 KASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTK 547
Query: 1264 VEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKPALPPASLAVAAIQREVS 1323
VE + D + AV + + S+ ES S E+ PL P S+ ++ V+
Sbjct: 548 VENNLIVDKATKKAVIVGKESKSAATKEESV-SLKEKTKPLTP-----SIGAKEKEQHVA 601
Query: 1324 LMHDEDPSQP-PPLPEGTQEPHLLRPDAAEKA 1354
L+ P P PP+ +E LR + + KA
Sbjct: 602 LVTSTLPPLPLPPMLPEDKEADSLRGNISVKA 633
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/198 (25%), Positives = 78/198 (39%), Gaps = 23/198 (11%)
Query: 1019 GTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKK-----AKDKS 1073
GT +S S + GE RR R + RRSSS RS R R R++ + S
Sbjct: 173 GTGGSGGSPASSSGTQRRGEGSERRPR---RDRRSSSGRSKERHREHRRRDGQRGGSEAS 229
Query: 1074 REHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCR 1133
+ R R ++SGS SS R+K ++S R+ + + +
Sbjct: 230 KSRSRHSHSGEERAEVAKSGSSSSSG-----GRRKSASATSSSSSSRKDRDSKAHRSRTK 284
Query: 1134 HKHQRERSHERPDR--KESVAWPRDRRKRRSRSPSS-------EHRAREHRRPRSREKWP 1184
+ +++ P + +E P+ R+RRS SP HRA + R R + P
Sbjct: 285 SSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSR-KSPSP 343
Query: 1185 QTRSHSPERKGAVREASP 1202
SP + R SP
Sbjct: 344 AGGGSSPYSRRLPRSPSP 361
Score = 36.6 bits (83), Expect = 0.21
Identities = 48/202 (23%), Positives = 79/202 (39%), Gaps = 15/202 (7%)
Query: 918 REEPTESQGLAARLRR--PSPPEPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDV 975
R+ P+ + G ++ R P P P+ S S S ER V P S
Sbjct: 338 RKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRH-SSYERGGD----VSPSPYSSSSW 392
Query: 976 LQAATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPS 1035
++ + LR +SRS S SR R R H +RS +R S S+ + S
Sbjct: 393 RRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSR----HRLSRSRSRHSSISPSTLTLKSS 448
Query: 1036 VGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSP 1095
+ E + ++++A +++ + + E K +A K+ + S T + S
Sbjct: 449 LAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKAS----NTSTPTKGNTETSA 504
Query: 1096 GSSSYEHYESRKKKKRRSASRP 1117
+S H + KK K A P
Sbjct: 505 SASQTNHVKDVKKIKIEHAPSP 526
Score = 32.3 bits (72), Expect = 3.9
Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 7/100 (7%)
Query: 319 GLSTAVYQRPLTPRTPA--RRKRKTRRRKKVPGRKKTPSGPSAKSKSSATRSKKRQHRVK 376
G ++ Y R L PR+P+ R+R + + PS S SS RS+ V
Sbjct: 345 GGGSSPYSRRL-PRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVL 403
Query: 377 KRRGKKVK----SEATTRSRIARTLGLRRPVHSSCIPSVL 412
+R GK S +RSR L R HSS PS L
Sbjct: 404 RRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTL 443
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 72.4 bits (176), Expect = 3e-12
Identities = 66/238 (27%), Positives = 98/238 (41%), Gaps = 41/238 (17%)
Query: 964 VVEPEAPPSPDVLQAATHRVVELRPPSRS-RSTSSSRSRKKAKRKRVSREH----GRTRS 1018
+ P PP P +Q H E R R+ R + R R+ +R+R E + R
Sbjct: 1113 IPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVRE 1172
Query: 1019 GTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRR 1078
G RS SR R +R R++R+K+K ++S + ++E K D R+ +
Sbjct: 1173 GPRSRSRSR-----------DRRRKERAKSKEKKSEK-KEKAQEEPPAKLLDDLFRKTKA 1220
Query: 1079 GP---W----------GHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPT 1125
P W + R R++ E E +K++ + A R R R+
Sbjct: 1221 APCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQE--EEEQKEREKEAERERNRQ---- 1274
Query: 1126 SSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRARE---HRRPRSR 1180
LER R +H RER ER +E RDR + R R E R+ H R RSR
Sbjct: 1275 --LEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSR 1330
Score = 54.7 bits (130), Expect = 7e-07
Identities = 122/491 (24%), Positives = 183/491 (37%), Gaps = 99/491 (20%)
Query: 915 DTEREEPTESQGLAARLRRPSPPEPWDEEDGASCSTF---FGSEERTVTCVTVVEPEAPP 971
+ E E SQGL + + PSPP ++ AS SEE T + E +PP
Sbjct: 368 EEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPP 427
Query: 972 SPDVLQA----------ATHRVVELRPPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTR 1021
L + A +++L PP+ T + VS+ + G
Sbjct: 428 PHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADT---------RELLVSQHTVQLVGGLS 478
Query: 1022 SESRDRSSRSASPS--VGEER--PRRQR------SKAKSRRSSSDRSSSRERAKRKK--- 1068
S +++ SP+ V EE P Q+ S K SDRS+ K ++
Sbjct: 479 PLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELAL 538
Query: 1069 --------AKDKSREHRRG-PWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRG 1119
K S E + G H+ S S SSS SR S+SR R
Sbjct: 539 AKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSS-----SRSSSSSSSSSRSRS 593
Query: 1120 RECSPTSSLERLCRHKHQRERSHERP-DRKESVAWPRDRRKRRSRSPSSEHRAREHRRPR 1178
R SP SS R H RS +R + + A PR R K SRS +SE R+R R R
Sbjct: 594 R--SPDSSGSR----SHSPLRSKQRDVAQARTHANPRGRPKMGSRS-TSESRSRSRSRSR 646
Query: 1179 SREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAP 1238
S + S RK S +P + T+ P+ G+ EVAT
Sbjct: 647 S--------ASSNSRK------SLSPGVSRDSSTSYTETKDPSSGQ-----EVAT----- 682
Query: 1239 LQAPPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQ--LDDMSSPPSPESTD- 1295
PPV ++ CEP + SV+A + S++ Q + SP E+ +
Sbjct: 683 ---PPVPQLQV-CEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEA 738
Query: 1296 -----SSPERDFPLKPALPPASLAVAAIQREVSLMHDEDPSQP------PPLPEGTQEPH 1344
+ P+ LP + ++ + + D ++P PP+P Q +
Sbjct: 739 EPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSN 798
Query: 1345 LLRPDAAEKAE 1355
RP+ + + E
Sbjct: 799 DDRPEGSVEDE 809
Score = 53.5 bits (127), Expect = 2e-06
Identities = 97/411 (23%), Positives = 149/411 (36%), Gaps = 30/411 (7%)
Query: 822 KQLRSEVYDPSDPTGSDSSAPGSSPE-RSGPGLLPSEITRT---ISINSPKAQTVQAVRC 877
+Q SE P ++S+P P+ S + P E I ++ P
Sbjct: 406 EQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELL 465
Query: 878 VTSYTVESIFGTEPEPPLGPSSAMSKLRGAVAAEGASDTEREEPTESQGLAARLRRPSPP 937
V+ +TV+ + G L P S+ S + AE + E P + A
Sbjct: 466 VSQHTVQLVGG------LSPLSSPSDTKAESPAEKVPE-ESVLPLVQKSTLADYSAQKDL 518
Query: 938 EPWDEEDGASCSTFFGSEERTVTCVTVVEPEAPPSPDVLQA--ATHRVVELRPPSRSRST 995
EP E D ++ EE + E PS + + A+H ++ +S +
Sbjct: 519 EP--ESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADS 576
Query: 996 SSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSS 1055
SSSRS + SR SG+RS S RS + R R K SR +S
Sbjct: 577 SSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSE 636
Query: 1056 DRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYES---------- 1105
RS SR R+ + A SR+ G SR +S S + + SS + +
Sbjct: 637 SRSRSRSRS--RSASSNSRKSLSP--GVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCE 692
Query: 1106 RKKKKRRSASRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSP 1165
K++ S+S + R S S E+ + Q ER + E P + + S +
Sbjct: 693 PKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQ 752
Query: 1166 SSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLP 1216
+S E EK T S R P P+A + +D P
Sbjct: 753 TSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIAD-QVSNDDRP 802
Score = 35.8 bits (81), Expect = 0.35
Identities = 89/405 (21%), Positives = 149/405 (36%), Gaps = 83/405 (20%)
Query: 1039 ERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSS 1098
ERP + S+ R+SS S S E+ K + E RR R ++ GS +
Sbjct: 192 ERPELELSRHSPRKSS---SISEEKGDSDDEKPRKGE-RRSSRVRQARAAKLSEGSQPAE 247
Query: 1099 SYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRHKHQR-----ERSHERP----DRKE 1149
E E+ + R A R E E + + ++S E P ++E
Sbjct: 248 EEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEE 307
Query: 1150 SVAWPR--------DRRKRRSR-----------SPSSEHRAREHRRPRSREKWPQTRSHS 1190
PR +R K RS+ + S E + H + +EK +T S
Sbjct: 308 GEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPL 367
Query: 1191 PERKGAVREA--------SPAPLAQGEPGREDLPTRLP--ALGEAHVSPEVATADKA--- 1237
E + ++ + SP+P E ++ LP E P + T + +
Sbjct: 368 EEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPP 427
Query: 1238 ------------PLQ--APPVLEVAAECEPDDLDLDYGDSVEAGHVFDDFSSDAVFIQLD 1283
P++ APPVL + P + D D + + + H L
Sbjct: 428 PHPQLHSEEEIEPMEGPAPPVL---IQLSPPNTDADTRELLVSQHTVQLVGG------LS 478
Query: 1284 DMSSPPSPESTDSSPERDFPLKPALP---PASLAVAAIQREVSLMHDEDPSQPPP----- 1335
+SSP ++ SP P + LP ++LA + Q+++ D +QP P
Sbjct: 479 PLSSPSDTKA--ESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRS-AQPLPLKIEE 535
Query: 1336 --LPEGTQEPHLLRPDAAEKAEAPSSPDVAPAG--KEDSPSASGR 1376
L +G E L +P +K +S + P+ K+ + S+S R
Sbjct: 536 LALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSR 580
Score = 35.8 bits (81), Expect = 0.35
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 10/111 (9%)
Query: 964 VVEPEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSR----KKAKRKRVSREHGRTRSG 1019
+V+ EA + + R + + R + R R ++ KR+ SRE R R
Sbjct: 1234 IVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERE- 1292
Query: 1020 TRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSS---RERAKRK 1067
R RDR R ER R+R + ++R S RS S R+R R+
Sbjct: 1293 -RERERDRGDRDRDRERDRER-GRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 35.0 bits (79), Expect = 0.60
Identities = 42/188 (22%), Positives = 73/188 (38%), Gaps = 32/188 (17%)
Query: 898 SSAMSKLRGAVAAEGASDTEREEPTESQGLAARLR---------RPSPPEPWDEEDGASC 948
SS + + R A +EG+ E EE E+ R+R E +E+D
Sbjct: 228 SSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEE 287
Query: 949 STFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRPPSRS-------RSTSSSRSR 1001
G + R + + E P V +++ RP +RS R +RS+
Sbjct: 288 GDDEGQKSREAPILKEFKEEGEEIPRV---KPEEMMDERPKTRSQEQEVLERGGRFTRSQ 344
Query: 1002 KKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSR 1061
++A++ ++R + +++ ++ SP EE R +S + S S R
Sbjct: 345 EEARKSHLAR-----------QQQEKEMKTTSPL--EEEEREIKSSQGLKEKSKSPSPPR 391
Query: 1062 ERAKRKKA 1069
RKKA
Sbjct: 392 LTEDRKKA 399
Score = 34.7 bits (78), Expect = 0.79
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 1137 QRERSHERPDRKESVA-WPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKG 1195
+RER ER +R S W RD+ + RS S R R +S+EK E+K
Sbjct: 1148 EREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEK-------KSEKKE 1200
Query: 1196 AVREASPAPL 1205
+E PA L
Sbjct: 1201 KAQEEPPAKL 1210
Score = 34.3 bits (77), Expect = 1.0
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 1002 KKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSR-RSSSDRSSS 1060
K+ +++R +E + + R+R+ + E R R + + R R DR
Sbjct: 1246 KEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRD 1305
Query: 1061 RERAKRKKAKDKSREHRRGPWGHSRRTSRS 1090
RER + + + R+ +R HSR SRS
Sbjct: 1306 RERDRERGRERDRRDTKR----HSRSRSRS 1331
Score = 33.5 bits (75), Expect = 1.7
Identities = 57/274 (20%), Positives = 98/274 (35%), Gaps = 24/274 (8%)
Query: 635 NKHTLPLASAASKISS-RDSKPPCRSVVPGPPLKPAPRRTDISELPRIPKIRRDDGGGRR 693
++HT+ L S +SS D+K PA + + S LP + K D ++
Sbjct: 467 SQHTVQLVGGLSPLSSPSDTKAE----------SPAEKVPEESVLPLVQKSTLADYSAQK 516
Query: 694 DAAPAHGQS-----IEIPSACISRLTGREGTGQPG----RGTRAESEA--SSRVPREPGV 742
D P +S ++I +++ E QP G RA S R+ +
Sbjct: 517 DLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADS 576
Query: 743 HTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRINIPGNMAHSSQLSSPGFCNTFRPV 802
+ S + SS S + S G S S + ++ H++ P + R
Sbjct: 577 SSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGS--RST 634
Query: 803 DDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPTGSDSSAPGSSPERSGPGLLPSEITRTI 862
+ R + S S K L V S + +++ P S E + P + ++
Sbjct: 635 SESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPK 694
Query: 863 SINSPKAQTVQAVRCVTSYTVESIFGTEPEPPLG 896
S + +VQA R + E +P G
Sbjct: 695 ERTSTSSSSVQARRLSQPESAEKHVTQRLQPERG 728
Score = 32.3 bits (72), Expect = 3.9
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Query: 335 ARRKRKTRRRKKVPG-----RKKTPSGPSAKSKSSATRSKKRQHRVKKRRGKKVKSEATT 389
A R+R+ RR++ R K GP ++S+S R K+R +K+ KK K++
Sbjct: 1147 AEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEP 1206
Query: 390 RSRIARTLGLRRPVHSSCI 408
+++ L R+ + CI
Sbjct: 1207 PAKLLDDL-FRKTKAAPCI 1224
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 71.6 bits (174), Expect = 6e-12
Identities = 28/47 (59%), Positives = 33/47 (70%)
Query: 186 CEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAA 232
C CGR + ED+LLLCDGCD YH CL PPL +VP +W CP+C A
Sbjct: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVA 342
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 71.6 bits (174), Expect = 6e-12
Identities = 28/47 (59%), Positives = 33/47 (70%)
Query: 186 CEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAA 232
C CGR + ED+LLLCDGCD YH CL PPL +VP +W CP+C A
Sbjct: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVA 342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,510,070
Number of Sequences: 37866
Number of extensions: 4670298
Number of successful extensions: 46489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 444
Number of HSP's successfully gapped in prelim test: 1534
Number of HSP's that attempted gapping in prelim test: 24766
Number of HSP's gapped (non-prelim): 14044
length of query: 1648
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1532
effective length of database: 13,855,062
effective search space: 21225954984
effective search space used: 21225954984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.