BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 [Homo sapiens] (686 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1389 0.0 gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 1331 0.0 gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 1326 0.0 gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 1323 0.0 gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1294 0.0 gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1293 0.0 gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1286 0.0 gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 984 0.0 gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 815 0.0 gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 573 e-163 gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 566 e-161 gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 465 e-131 gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 457 e-128 gi|239755300 PREDICTED: similar to centaurin, gamma-like family,... 347 2e-95 gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens] 169 6e-42 gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens] 169 6e-42 gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens] 169 6e-42 gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 141 2e-33 gi|187608516 centaurin, beta 2 [Homo sapiens] 127 3e-29 gi|7661880 centaurin beta1 [Homo sapiens] 126 8e-29 gi|46094081 development and differentiation enhancing factor 1 [... 124 4e-28 gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 117 5e-26 gi|206725420 G protein-coupled receptor kinase interacting ArfGA... 117 5e-26 gi|21237786 G protein-coupled receptor kinase interacting ArfGAP... 117 5e-26 gi|17149830 G protein-coupled receptor kinase interacting ArfGAP... 117 5e-26 gi|17149832 G protein-coupled receptor kinase interacting ArfGAP... 117 5e-26 gi|206725415 G protein-coupled receptor kinase interacting ArfGA... 117 5e-26 gi|146231998 G protein-coupled receptor kinase interactor 1 isof... 115 2e-25 gi|41393573 G protein-coupled receptor kinase interactor 1 isofo... 115 2e-25 gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 114 4e-25 >gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 [Homo sapiens] Length = 686 Score = 1389 bits (3594), Expect = 0.0 Identities = 686/686 (100%), Positives = 686/686 (100%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA Sbjct: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL Sbjct: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPDECV Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686 >gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] Length = 686 Score = 1331 bits (3444), Expect = 0.0 Identities = 660/686 (96%), Positives = 668/686 (97%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESE YEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESETYEAGARDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMHH+RD+EMPEALEF+LSANPE+STIFQRNSQT+ALEFNPSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHVRDREMPEALEFNLSANPESSTIFQRNSQTEALEFNPSANPEASTIFQRNSQTD 120 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVS RFSQQYS CSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSAVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DR+LSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 181 DRTLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNG+LTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PISSSKS Sbjct: 301 KKKYVTLCSNGMLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 360 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 D ETQNPKWASLNLGVLMCIECSGIHRSLG LSRVRSLELDDWPVELRKVMSSI NDLA Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSSIVNDLA 540 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQGQTKPS KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQ LLRATADEDL Sbjct: 541 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 600 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGS EEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPDECV Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686 >gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 [Homo sapiens] Length = 684 Score = 1326 bits (3431), Expect = 0.0 Identities = 661/686 (96%), Positives = 667/686 (97%), Gaps = 2/686 (0%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMH +RD+EMPEALEF+LSANPEASTIFQRNSQTDALEFN SANPEASTIFQRNSQTD Sbjct: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 D ETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQGQTKPS+KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQ LLRAT DEDL Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPDECV Sbjct: 659 LTYARQASSQECINVLLQYGCPDECV 684 >gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat and PH domain 10 [Homo sapiens] Length = 684 Score = 1323 bits (3424), Expect = 0.0 Identities = 660/686 (96%), Positives = 666/686 (97%), Gaps = 2/686 (0%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMH +RD+EMPEALEF+LSANPEASTIFQRNSQTDALEFN SANPEASTIFQRNSQTD Sbjct: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCK SMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 NGLSKDMDTGLGDSICFSP ISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 D ETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQGQTKPS+KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQ LLRAT DEDL Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPDECV Sbjct: 659 LTYARQASSQECINVLLQYGCPDECV 684 >gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 [Homo sapiens] Length = 663 Score = 1294 bits (3349), Expect = 0.0 Identities = 646/686 (94%), Positives = 652/686 (95%), Gaps = 23/686 (3%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMHH+RD+EMPEALEF NPSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHVRDREMPEALEF-----------------------NPSANPEASTIFQRNSQTD 97 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVST RFSQQYS CSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 98 VVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 158 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PIS+SKS Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSKS 337 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 338 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQS+AMALQSIQNMRGNAHCV Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSKAMALQSIQNMRGNAHCV 457 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 D ETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQGQTKPS KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQ LLRATADEDL Sbjct: 518 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPD+CV Sbjct: 638 LTYARQASSQECINVLLQYGCPDKCV 663 >gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH domain 8 [Homo sapiens] Length = 663 Score = 1293 bits (3347), Expect = 0.0 Identities = 647/686 (94%), Positives = 650/686 (94%), Gaps = 23/686 (3%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMHH+RD+EMPEALEF NPSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHVRDREMPEALEF-----------------------NPSANPEASTIFQRNSQTD 97 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVST RFSQQYS CSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 98 VVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 158 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDL+TSTIKVPGKWPSLATSAC PISSSKS Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 337 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 338 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 D ETQNPKWASLNLGVLMCIECSGIH SLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQGQTKPS KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQ LL ATADEDL Sbjct: 518 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLWATADEDL 577 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPDECV Sbjct: 638 LTYARQASSQECINVLLQYGCPDECV 663 >gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7 [Homo sapiens] Length = 663 Score = 1286 bits (3327), Expect = 0.0 Identities = 643/686 (93%), Positives = 649/686 (94%), Gaps = 23/686 (3%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 DLHMHH+RD+EMPEALEF NPSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHVRDREMPEALEF-----------------------NPSANPEASTIFQRNSQTD 97 Query: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 VVEIRRSNCTNHVST FSQQYS CSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 98 VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 Query: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 Query: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS Sbjct: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337 Query: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 +GLSKDMDTGLGDSICFSPSISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 Query: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457 Query: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 D ETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA Sbjct: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 Query: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 NSIWEGSSQG+TKP+ KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQ LLRATADEDL Sbjct: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577 Query: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 Query: 661 LTYARQASSQECINVLLQYGCPDECV 686 LTYARQASSQECINVLLQYGCPDECV Sbjct: 638 LTYARQASSQECINVLLQYGCPDECV 663 >gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating protein 11 [Homo sapiens] Length = 550 Score = 984 bits (2543), Expect = 0.0 Identities = 497/550 (90%), Positives = 508/550 (92%), Gaps = 25/550 (4%) Query: 162 MTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPST 221 MTIISVTLEI HHIT+RDADRSL+I DEQL+SFA STVHITK RNGGGSLNNYSSSIP T Sbjct: 1 MTIISVTLEIHHHITERDADRSLTILDEQLYSFAFSTVHITKKRNGGGSLNNYSSSIPLT 60 Query: 222 PSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRA 281 PSTSQED FSVPPTANTPTP+CK+SM WSNLFTSEKGS PDK RKA E+HADTIGSGRA Sbjct: 61 PSTSQEDLYFSVPPTANTPTPICKQSMGWSNLFTSEKGSDPDKGRKALESHADTIGSGRA 120 Query: 282 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 341 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP Sbjct: 121 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 180 Query: 342 GKWPSLATSACAPISSSKSNGLSKDM---------DTGLGDSICFSPSISSTTSPKLNPP 392 GKWPSLATSACAPISSSKSNGLSKDM D GLGDSICFSPSISSTTSPKLN P Sbjct: 181 GKWPSLATSACAPISSSKSNGLSKDMEALHMSANSDIGLGDSICFSPSISSTTSPKLNLP 240 Query: 393 PSPHANKKKHLKKKSTNN----------------FMIVSATGQTWHFEATTYEERDAWVQ 436 PSPHANKKKHLKKKSTNN FMIVS TGQT HF+ATTYEERDAWVQ Sbjct: 241 PSPHANKKKHLKKKSTNNLKDDGLSSTAEEEEEKFMIVSVTGQTCHFKATTYEERDAWVQ 300 Query: 437 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGV 496 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGN+HCVD ETQNPKWASLNLGV Sbjct: 301 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGV 360 Query: 497 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSV 556 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPS+ Sbjct: 361 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSI 420 Query: 557 KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDLQTAILLLAHGSREEVN 616 +STREEKERWIRSKYE KLFLAPLPCTELSLGQHLLRATADEDL+TAILLLAHGSREEVN Sbjct: 421 ESTREEKERWIRSKYEHKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSREEVN 480 Query: 617 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 676 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL Sbjct: 481 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 540 Query: 677 LQYGCPDECV 686 LQYGCPDECV Sbjct: 541 LQYGCPDECV 550 >gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] Length = 804 Score = 815 bits (2106), Expect = 0.0 Identities = 415/532 (78%), Positives = 456/532 (85%), Gaps = 32/532 (6%) Query: 185 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 S+P+ HS VS VHI++ NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299 TPV K+S R SNLFTS KGS PDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364 Query: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359 WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424 Query: 360 SNGLSKDM---------DTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410 +NGLSKDM DTGLGDS+C SPSISSTTSPKL+PPPSPHAN+KKH +KKST+N Sbjct: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484 Query: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 452 F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS Sbjct: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544 Query: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTR 512 K+KS+LTSQSEAMALQSI+NMRGN+HCVD ETQNP WASLNLG LMCIECSGIHR+LGT Sbjct: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604 Query: 513 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSVKSTREEKERWIRSKYE 572 LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQG+TKPSV STREEKERWIR+KYE Sbjct: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664 Query: 573 EKLFLAPLPCTELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 632 +KLFLAPLPCTELSLGQHLLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC Sbjct: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724 Query: 633 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 684 RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE Sbjct: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776 >gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] Length = 857 Score = 573 bits (1478), Expect = e-163 Identities = 289/369 (78%), Positives = 315/369 (85%), Gaps = 28/369 (7%) Query: 334 RTSTIKVPGKWPSLATSACAPISSSKSNGLSKDMDTGLGDSICFSPSISSTTSPKLNPPP 393 R+ ++ +W A + ISS DTGLGDS+C SPSISSTTSPKL+PPP Sbjct: 471 RSYSVSSADQWSEATVIANSAISS----------DTGLGDSVCSSPSISSTTSPKLDPPP 520 Query: 394 SPHANKKKHLKKKSTNNF------------------MIVSATGQTWHFEATTYEERDAWV 435 SPHAN+KKH +KKST+NF +IVS TGQTWHFEATTYEERDAWV Sbjct: 521 SPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWV 580 Query: 436 QAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLG 495 QAI+SQILASLQSCESSK+KS+LTSQSEAMALQSI+NMRGN+HCVD ETQNP WASLNLG Sbjct: 581 QAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLG 640 Query: 496 VLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPS 555 LMCIECSGIHR+LGT LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQG+TKPS Sbjct: 641 ALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPS 700 Query: 556 VKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDLQTAILLLAHGSREEV 615 V STREEKERWIR+KYE+KLFLAPLPCTELSLGQHLLRATADEDL+TAILLLAHGSR+EV Sbjct: 701 VDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEV 760 Query: 616 NETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINV 675 NETCGEGDG TALHLACRKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+V Sbjct: 761 NETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDV 820 Query: 676 LLQYGCPDE 684 LLQYGCPDE Sbjct: 821 LLQYGCPDE 829 Score = 258 bits (659), Expect = 1e-68 Identities = 137/207 (66%), Positives = 160/207 (77%), Gaps = 10/207 (4%) Query: 185 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 S+P+ HS VS VHI++ NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304 Query: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299 TPV K+S R SNLFTS KGS PDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364 Query: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359 WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424 Query: 360 SNGLSKDMDTGLGDSICFSPSISSTTS 386 +NGLSKDM S+ SP+ + TS Sbjct: 425 TNGLSKDM-----SSLHISPNSGNVTS 446 >gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] Length = 911 Score = 566 bits (1459), Expect = e-161 Identities = 304/582 (52%), Positives = 387/582 (66%), Gaps = 82/582 (14%) Query: 185 SIPDEQLHSF----AVSTVHITKNRNGGGS-LNNYSSSIPSTPSTSQEDPQFSVPPTANT 239 S+P+ HS ++ VHI + NGGGS ++YSSS+PSTPS SQ + + ++T Sbjct: 301 SLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASST 360 Query: 240 PTPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-K 298 PTP+ K+S R SN+FTS KG+ D+E+KA E D+IGSGRAIPIKQG+LLKRSGK L K Sbjct: 361 PTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNK 420 Query: 299 TWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAP---- 354 WKKKYVTLC NG+LTY+ SL DYM+NIH KEIDL +T+KVPGK AT A AP Sbjct: 421 EWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPATAPGTSP 480 Query: 355 ----ISSSKSN--------------GLSKDMDTGLGDSICFSP----------SISS--- 383 +S +SN S + L S P S+SS Sbjct: 481 RANGLSVERSNTQLGGGTGAPHSASSASLHSERPLSSSAWAGPRPEGLHQRSCSVSSADQ 540 Query: 384 -----------------------TTSPKLNPPPSPHANKKKHLKKKSTNN---------- 410 ++SPKL+PPPSPH+N+KKH +KKST Sbjct: 541 WSEATTSLPPGMQHPASGPAEVLSSSPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSAT 600 Query: 411 --------FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQS 462 F++VS TGQTWHFEA+T EER+ WVQ++Q+QILASLQ C S+K K++L +Q+ Sbjct: 601 EEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQN 660 Query: 463 EAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD 522 A+A+Q+++ +RGN+ C+D + NP WASLNLG LMCIECSGIHR LG LSRVRSL+LD Sbjct: 661 AALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLD 720 Query: 523 DWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPC 582 DWP EL VM+++GN LANS+WEG+ G +KP + REEKERWIR+KYE+KLFLAPLP Sbjct: 721 DWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLPS 780 Query: 583 TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQL 642 +++ LGQ LLRA ++DL+ ++LLAHGS+EEVNET G+GDG TALHL+ NVV QL Sbjct: 781 SDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQL 840 Query: 643 LIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 684 LIWYGVDV +RDA G T L YAR+A SQEC ++L+Q+GCP E Sbjct: 841 LIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGE 882 >gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] Length = 836 Score = 465 bits (1197), Expect = e-131 Identities = 264/557 (47%), Positives = 344/557 (61%), Gaps = 63/557 (11%) Query: 185 SIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTP-- 242 S+P HS A + V + GG ++YSSS+PS+P+ + + A TP Sbjct: 245 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 302 Query: 243 VCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 301 + + + R ++LF + +GS D E+++ ++ +T GSGRAIPIKQ LLKRSG L K WK Sbjct: 303 LHRAAKRRTSLFANRRGS--DSEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 360 Query: 302 KKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSN 361 KKYVTL SNG L Y+ S+ DY+ + H KE+DL +T+KVPGK P A SA P S+ N Sbjct: 361 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 418 Query: 362 GLSKDMDT-GLGDSI-------CFSPSISSTTSP-------------------------- 387 GL KDM T +G+ + SPS SS P Sbjct: 419 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 478 Query: 388 ------KLNPPPSPHANKKKHLK--------------KKSTNNFMIVSATGQTWHFEATT 427 PPPSP K++ K ++ F+IVS+TGQTWHFEA + Sbjct: 479 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEEENFEFLIVSSTGQTWHFEAAS 538 Query: 428 YEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNP 487 +EERDAWVQAI+SQILASLQ CESSK K + SQSEA+A+Q+I+N +GN+ CVD NP Sbjct: 539 FEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNP 598 Query: 488 KWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS 547 WASLNLG L+CIECSGIHR+LGT LSRVRSL+LDDWP EL V+++IGND AN +WE Sbjct: 599 TWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESD 658 Query: 548 SQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDLQTAILLL 607 ++G+ KPS S+REE+E WIR+KYE+ LFLAPL +E LG+ L A +D+ T +LLL Sbjct: 659 TRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLL 718 Query: 608 AHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQA 667 AH ++ + + + LHLA +VV+ QLL+WYG DV ARDA G TAL YARQA Sbjct: 719 AHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYARQA 778 Query: 668 SSQECINVLLQYGCPDE 684 SQ C ++LLQ+GCP E Sbjct: 779 GSQLCADILLQHGCPGE 795 >gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] Length = 1192 Score = 457 bits (1176), Expect = e-128 Identities = 264/577 (45%), Positives = 344/577 (59%), Gaps = 83/577 (14%) Query: 185 SIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTP-- 242 S+P HS A + V + GG ++YSSS+PS+P+ + + A TP Sbjct: 581 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 638 Query: 243 VCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 301 + + + R ++LF + +GS D E+++ ++ +T GSGRAIPIKQ LLKRSG L K WK Sbjct: 639 LHRAAKRRTSLFANRRGS--DSEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 696 Query: 302 KKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSN 361 KKYVTL SNG L Y+ S+ DY+ + H KE+DL +T+KVPGK P A SA P S+ N Sbjct: 697 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 754 Query: 362 GLSKDMDT-GLGDSI-------CFSPSISSTTSP-------------------------- 387 GL KDM T +G+ + SPS SS P Sbjct: 755 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 814 Query: 388 ------KLNPPPSPHANKKKHLKKKSTNN------------------------------- 410 PPPSP K++ K + + Sbjct: 815 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEAKRKMWKLKSFGSLRNIYKAEE 874 Query: 411 ---FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMAL 467 F+IVS+TGQTWHFEA ++EERDAWVQAI+SQILASLQ CESSK K + SQSEA+A+ Sbjct: 875 NFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAI 934 Query: 468 QSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVE 527 Q+I+N +GN+ CVD NP WASLNLG L+CIECSGIHR+LGT LSRVRSL+LDDWP E Sbjct: 935 QAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRE 994 Query: 528 LRKVMSSIGNDLANSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSL 587 L V+++IGND AN +WE ++G+ KPS S+REE+E WIR+KYE+ LFLAPL +E L Sbjct: 995 LTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPL 1054 Query: 588 GQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYG 647 G+ L A +D+ T +LLLAH ++ + + + LHLA +VV+ QLL+WYG Sbjct: 1055 GRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYG 1114 Query: 648 VDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 684 DV ARDA G TAL YARQA SQ C ++LLQ+GCP E Sbjct: 1115 ADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGE 1151 >gi|239755300 PREDICTED: similar to centaurin, gamma-like family, member 1 [Homo sapiens] Length = 284 Score = 347 bits (890), Expect = 2e-95 Identities = 170/173 (98%), Positives = 171/173 (98%) Query: 514 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSVKSTREEKERWIRSKYEE 573 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPS KSTREEKERWIRSKYEE Sbjct: 112 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEE 171 Query: 574 KLFLAPLPCTELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 633 KLFLAPLPCT+LSLGQ LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR Sbjct: 172 KLFLAPLPCTDLSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 231 Query: 634 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 686 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV Sbjct: 232 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 284 Score = 39.7 bits (91), Expect = 0.009 Identities = 18/18 (100%), Positives = 18/18 (100%) Query: 178 RDADRSLSIPDEQLHSFA 195 RDADRSLSIPDEQLHSFA Sbjct: 94 RDADRSLSIPDEQLHSFA 111 >gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens] Length = 362 Score = 169 bits (429), Expect = 6e-42 Identities = 105/200 (52%), Positives = 121/200 (60%), Gaps = 28/200 (14%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCCV P S Q QG VC ESEIYEA AGD +AG P+AAAV+P EVT GE Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60 Query: 61 DLHMHHIRDQEMPE--ALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQ 118 LHMHHI ++EMPE LE + S +P+ASTIF R SQTD Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99 Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISV--TLEIPHHIT 176 V+ ++ VSTE F+QQYSSCSTIFLDDS ASQ +LTMT+ S I + Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156 Query: 177 QRDADRSLSIPDEQLHSFAV 196 +RDA RSL I DEQLH V Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176 >gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens] Length = 362 Score = 169 bits (429), Expect = 6e-42 Identities = 105/200 (52%), Positives = 121/200 (60%), Gaps = 28/200 (14%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCCV P S Q QG VC ESEIYEA AGD +AG P+AAAV+P EVT GE Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60 Query: 61 DLHMHHIRDQEMPE--ALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQ 118 LHMHHI ++EMPE LE + S +P+ASTIF R SQTD Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99 Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISV--TLEIPHHIT 176 V+ ++ VSTE F+QQYSSCSTIFLDDS ASQ +LTMT+ S I + Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156 Query: 177 QRDADRSLSIPDEQLHSFAV 196 +RDA RSL I DEQLH V Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176 >gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens] Length = 362 Score = 169 bits (429), Expect = 6e-42 Identities = 105/200 (52%), Positives = 121/200 (60%), Gaps = 28/200 (14%) Query: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCCV P S Q QG VC ESEIYEA AGD +AG P+AAAV+P EVT GE Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60 Query: 61 DLHMHHIRDQEMPE--ALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQ 118 LHMHHI ++EMPE LE + S +P+ASTIF R SQTD Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTD--------------------- 99 Query: 119 TDVVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISV--TLEIPHHIT 176 V+ ++ VSTE F+QQYSSCSTIFLDDS ASQ +LTMT+ S I + Sbjct: 100 ---VQEKKKKQLCKVSTEHFTQQYSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQA 156 Query: 177 QRDADRSLSIPDEQLHSFAV 196 +RDA RSL I DEQLH V Sbjct: 157 KRDAHRSLGIFDEQLHPLTV 176 >gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [Homo sapiens] Length = 834 Score = 141 bits (355), Expect = 2e-33 Identities = 80/192 (41%), Positives = 113/192 (58%), Gaps = 22/192 (11%) Query: 411 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQ----SCES-------SKSKSQLT 459 F ++S T ++ +A + + R AWVQA+Q+ I ++ + SC S S S S + Sbjct: 332 FEVLSPT-KSCMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSID 390 Query: 460 SQSEAM--------ALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGT 511 S ++ LQ +Q++ GN+ C D +P+WAS+NLGVL+CIECSGIHRSLG Sbjct: 391 SATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGV 450 Query: 512 RLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQ--GQTKPSVKSTREEKERWIRS 569 S+VRSL LD W EL K+M +GN N I+E + G KP+ S+R++KE WI+ Sbjct: 451 HCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKD 510 Query: 570 KYEEKLFLAPLP 581 KY EK FL P Sbjct: 511 KYVEKKFLRKAP 522 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 584 ELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLL 643 EL G RA DL LAHG+ EVN E +G T L A G++++ + L Sbjct: 665 ELHPGLLAHRAARARDLPALAAALAHGA--EVNWADAEDEGKTPLVQAVLGGSLIVCEFL 722 Query: 644 IWYGVDVMARDAHGNTALTYA 664 + G DV RD+ G L +A Sbjct: 723 LQNGADVNQRDSRGRAPLHHA 743 >gi|187608516 centaurin, beta 2 [Homo sapiens] Length = 778 Score = 127 bits (320), Expect = 3e-29 Identities = 75/186 (40%), Positives = 109/186 (58%), Gaps = 21/186 (11%) Query: 411 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSC---------ESSKSKSQLTSQ 461 F +VS T ++ +A + + R AW++A+Q+ I + + +SS S L S Sbjct: 330 FEVVSPT-KSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSG 388 Query: 462 SEAM--------ALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRL 513 +E+ ALQ +Q + GNA C D +P+WAS+NLG+ +CIECSGIHRSLG Sbjct: 389 NESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHF 448 Query: 514 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS--SQGQTKPSVKSTREEKERWIRSKY 571 S+VRSL LD W EL K+M +GND+ N ++E + G KP R+EKE +IR+KY Sbjct: 449 SKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQ-PGQRQEKEAYIRAKY 507 Query: 572 EEKLFL 577 E+ F+ Sbjct: 508 VERKFV 513 Score = 36.6 bits (83), Expect = 0.079 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Query: 580 LPCTELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL 639 L L+ G L RA+ +++L LAHG+ +VN E + T L A G++V Sbjct: 599 LDSKHLNPGLQLYRASYEKNLPKMAEALAHGA--DVNWANSEENKATPLIQAVLGGSLVT 656 Query: 640 AQLLIWYGVDVMARDAHGNTALTYA 664 + L+ G +V RD G L +A Sbjct: 657 CEFLLQNGANVNQRDVQGRGPLHHA 681 >gi|7661880 centaurin beta1 [Homo sapiens] Length = 740 Score = 126 bits (316), Expect = 8e-29 Identities = 123/428 (28%), Positives = 173/428 (40%), Gaps = 94/428 (21%) Query: 284 IKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGK 343 + +G L KR+ KTW +++ T+ SN L Y D + + DLR T+K+ Sbjct: 267 VMEGHLFKRASNAFKTWSRRWFTIQSN-QLVYQKKYKDPVTVVVD---DLRLCTVKL--- 319 Query: 344 WPSLATSAC-APISSSKSNGLSKDMD--TGLGDSICFSPSISSTTSPKLNPPPSPHANKK 400 P C +S+SKS L D + L S S S+ + +L+ P Sbjct: 320 CPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGS 379 Query: 401 KHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTS 460 HL AI S A+L S ++ + Sbjct: 380 GHL---------------------------------AIGS--AATLGSGGMARGRE---P 401 Query: 461 QSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLE 520 + +Q++ GNA C D P+WAS+NLGV +CI+CSGIHRSLG S+VRSL Sbjct: 402 GGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLT 461 Query: 521 LDDWPVELRKVMSSIGNDLANSIWEGSSQGQT--KPSVKSTREEKERWIRSKYEEKLFLA 578 LD W EL K+M +GN + N I+E + KP +R+EKE WI +KY EK FL Sbjct: 462 LDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLT 521 Query: 579 PLP-----------------------------------------CTELSLGQHLLRATA- 596 LP L G L RA+ Sbjct: 522 KLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGH 581 Query: 597 DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAH 656 L T LAHG+ +VN G D T L A +++ + L+ G +V D+ Sbjct: 582 PPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSA 639 Query: 657 GNTALTYA 664 G L +A Sbjct: 640 GRGPLHHA 647 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 591 LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 650 L++ATA L LL +G+ ++ G G LH A G+ LA L + G D+ Sbjct: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666 Query: 651 MARDAHGNTALTYARQASSQECINVL 676 ARD+ G LT A + ++ + + +L Sbjct: 667 GARDSEGRDPLTIAMETANADIVTLL 692 >gi|46094081 development and differentiation enhancing factor 1 [Homo sapiens] Length = 1129 Score = 124 bits (310), Expect = 4e-28 Identities = 91/293 (31%), Positives = 142/293 (48%), Gaps = 20/293 (6%) Query: 395 PHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAI---QSQILASLQSCES 451 P+A KK S N +T+HF+A ++ AW+ + + + L E Sbjct: 377 PNAEDKKSFDLISHN---------RTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQ 427 Query: 452 SKSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGT 511 S ++ L ++A+ ++ +Q + GN C D + P W S NLG+L CIECSGIHR +G Sbjct: 428 SAGENSLEDLTKAI-IEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGV 486 Query: 512 RLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQT-KPSVKSTREEKERWIRSK 570 +SR++SLELD + ++GN+ N I E + + KP+ S ++ +I +K Sbjct: 487 HISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAK 546 Query: 571 YEEKLFLAPLPCTELSLGQHLLRATADEDLQTAILLLAHGSR--EEVNETCGEGDGCTAL 628 Y + F T + LL A DL I + A G E + E G+ G TAL Sbjct: 547 YVDHRFSRKTCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEP-GQELGETAL 605 Query: 629 HLACR---KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 HLA R + ++ L L+ ++ + A GNT L Y S EC+ +LL+ Sbjct: 606 HLAVRTADQTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLR 658 >gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 5 [Homo sapiens] Length = 729 Score = 117 bits (292), Expect = 5e-26 Identities = 72/222 (32%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 471 QNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 530 + +R + C D +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 531 VMSSIGNDLANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC 582 ++ ++ N+ ANSIWE S G+ K + + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 583 ------TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636 T L + L + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 637 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 6 [Homo sapiens] Length = 681 Score = 117 bits (292), Expect = 5e-26 Identities = 72/222 (32%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 471 QNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 530 + +R + C D +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 531 VMSSIGNDLANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC 582 ++ ++ N+ ANSIWE S G+ K + + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 583 ------TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636 T L + L + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 637 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 3 [Homo sapiens] Length = 679 Score = 117 bits (292), Expect = 5e-26 Identities = 72/222 (32%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 471 QNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 530 + +R + C D +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 531 VMSSIGNDLANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC 582 ++ ++ N+ ANSIWE S G+ K + + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 583 ------TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636 T L + L + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 637 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 1 [Homo sapiens] Length = 759 Score = 117 bits (292), Expect = 5e-26 Identities = 72/222 (32%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 471 QNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 530 + +R + C D +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 531 VMSSIGNDLANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC 582 ++ ++ N+ ANSIWE S G+ K + + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 583 ------TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636 T L + L + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 637 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|17149832 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 2 [Homo sapiens] Length = 631 Score = 117 bits (292), Expect = 5e-26 Identities = 72/222 (32%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 471 QNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 530 + +R + C D +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 531 VMSSIGNDLANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC 582 ++ ++ N+ ANSIWE S G+ K + + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 583 ------TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636 T L + L + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 637 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|206725415 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 4 [Homo sapiens] Length = 471 Score = 117 bits (292), Expect = 5e-26 Identities = 72/222 (32%), Positives = 113/222 (50%), Gaps = 17/222 (7%) Query: 471 QNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 530 + +R + C D +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 531 VMSSIGNDLANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC 582 ++ ++ N+ ANSIWE S G+ K + + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 583 ------TELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 636 T L + L + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 637 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|146231998 G protein-coupled receptor kinase interactor 1 isoform 1 [Homo sapiens] Length = 770 Score = 115 bits (287), Expect = 2e-25 Identities = 71/214 (33%), Positives = 110/214 (51%), Gaps = 17/214 (7%) Query: 479 CVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGND 538 C D +P WAS++ GVL+C EC +HRSLG +S V+ L WP L +++ ++ ++ Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70 Query: 539 LANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC------TE 584 ANSIWE S G+ K + + K +IR+KY+ F+ LPC T Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130 Query: 585 LSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLI 644 L + L + +L+T + LL+ G++ G T LH+A + G + A+LL+ Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187 Query: 645 WYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 YG D + D +G T + YARQA E L++ Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221 >gi|41393573 G protein-coupled receptor kinase interactor 1 isoform 2 [Homo sapiens] Length = 761 Score = 115 bits (287), Expect = 2e-25 Identities = 71/214 (33%), Positives = 110/214 (51%), Gaps = 17/214 (7%) Query: 479 CVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGND 538 C D +P WAS++ GVL+C EC +HRSLG +S V+ L WP L +++ ++ ++ Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70 Query: 539 LANSIWEGS-------SQGQTKPSVK-STREEKERWIRSKYEEKLFLAPLPC------TE 584 ANSIWE S G+ K + + K +IR+KY+ F+ LPC T Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130 Query: 585 LSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLI 644 L + L + +L+T + LL+ G++ G T LH+A + G + A+LL+ Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187 Query: 645 WYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 YG D + D +G T + YARQA E L++ Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221 >gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 isoform b [Homo sapiens] Length = 894 Score = 114 bits (284), Expect = 4e-25 Identities = 88/279 (31%), Positives = 133/279 (47%), Gaps = 24/279 (8%) Query: 419 QTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEA-----------MAL 467 +T+HF+A E +AWV +Q+ +L S + + S A + + Sbjct: 361 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 420 Query: 468 QSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPV 526 +++ GN+ C D +P W S NLGVL CI+CSG+HR LG R SR++SL LD P Sbjct: 421 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 480 Query: 527 ELRKVMSSIGNDLANSIWEGS--SQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTE 584 EL + ++GN N + E S G KPS +S + +I +KY E F CT Sbjct: 481 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 537 Query: 585 LSLGQHLLRATADEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGN---VVL 639 Q L A + DL + + A+G + + + LHLA + N + L Sbjct: 538 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595 Query: 640 AQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 678 +I G + A+ A GNTAL YA + +C+ +LL+ Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 634 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.126 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,894,951 Number of Sequences: 37866 Number of extensions: 1228312 Number of successful extensions: 5724 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 339 Number of HSP's successfully gapped in prelim test: 90 Number of HSP's that attempted gapping in prelim test: 4128 Number of HSP's gapped (non-prelim): 1496 length of query: 686 length of database: 18,247,518 effective HSP length: 109 effective length of query: 577 effective length of database: 14,120,124 effective search space: 8147311548 effective search space used: 8147311548 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.