Search of human proteins with 22035612

Search of human proteins with 22035612

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
         (938 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...  1909   0.0  
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...  1821   0.0  
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...  1033   0.0  
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...   997   0.0  
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...   987   0.0  
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...   951   0.0  
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]   831   0.0  
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   295   2e-79
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   289   7e-78
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   285   2e-76
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   282   1e-75
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]      271   2e-72
gi|4505531 oxysterol binding protein [Homo sapiens]                   268   2e-71
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   115   1e-25
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   115   1e-25
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   115   1e-25
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...   100   1e-20
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...    99   1e-20
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    99   1e-20
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...    99   1e-20
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...    99   1e-20
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...    99   1e-20
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...    99   1e-20
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...    99   1e-20
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...    98   3e-20
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...    98   3e-20
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           80   9e-15
gi|217416392 pleckstrin homology domain containing, family H (wi...    52   3e-06
gi|55741447 pleckstrin homology domain containing, family H (wit...    46   2e-04
gi|83716021 GRB2-associated binding protein family, member 4 [Ho...    42   0.003

>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score = 1909 bits (4944), Expect = 0.0
 Identities = 938/938 (100%), Positives = 938/938 (100%)

Query: 1   MHQLSLIRGNRGRSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQT 60
           MHQLSLIRGNRGRSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQT
Sbjct: 1   MHQLSLIRGNRGRSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQT 60

Query: 61  NVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVM 120
           NVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVM
Sbjct: 61  NVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVM 120

Query: 121 SIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPS 180
           SIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPS
Sbjct: 121 SIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPS 180

Query: 181 TSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRC 240
           TSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRC
Sbjct: 181 TSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRC 240

Query: 241 AEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVS 300
           AEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVS
Sbjct: 241 AEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVS 300

Query: 301 KDTKIQLQEGPPAKGQFSTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQT 360
           KDTKIQLQEGPPAKGQFSTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQT
Sbjct: 301 KDTKIQLQEGPPAKGQFSTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQT 360

Query: 361 PPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGH 420
           PPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGH
Sbjct: 361 PPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGH 420

Query: 421 STQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPL 480
           STQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPL
Sbjct: 421 STQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPL 480

Query: 481 SQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADN 540
           SQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADN
Sbjct: 481 SQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADN 540

Query: 541 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPL 600
           ISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPL
Sbjct: 541 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPL 600

Query: 601 NTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETY 660
           NTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETY
Sbjct: 601 NTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETY 660

Query: 661 ECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVM 720
           ECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVM
Sbjct: 661 ECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVM 720

Query: 721 LPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMN 780
           LPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMN
Sbjct: 721 LPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMN 780

Query: 781 EVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELN 840
           EVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELN
Sbjct: 781 EVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELN 840

Query: 841 ELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK 900
           ELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK
Sbjct: 841 ELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK 900

Query: 901 FFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 938
           FFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW
Sbjct: 901 FFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 938


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 1821 bits (4718), Expect = 0.0
 Identities = 900/926 (97%), Positives = 901/926 (97%), Gaps = 25/926 (2%)

Query: 13  RSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFM 72
           +SIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFM
Sbjct: 34  QSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFM 93

Query: 73  LKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLD 132
           LKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLD
Sbjct: 94  LKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLD 153

Query: 133 TEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV 192
           TEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV
Sbjct: 154 TEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV 213

Query: 193 SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLV 252
           SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLV
Sbjct: 214 SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLV 273

Query: 253 ELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPP 312
           ELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQ    
Sbjct: 274 ELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQ---- 329

Query: 313 AKGQFSTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESS 372
                                VPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESS
Sbjct: 330 ---------------------VPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESS 368

Query: 373 TDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLS 432
           TDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLS
Sbjct: 369 TDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLS 428

Query: 433 QALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSM 492
           QALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSM
Sbjct: 429 QALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSM 488

Query: 493 SESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTG 552
           SESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTG
Sbjct: 489 SESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTG 548

Query: 553 GAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEY 612
           GAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEY
Sbjct: 549 GAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEY 608

Query: 613 SELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFF 672
           SELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFF
Sbjct: 609 SELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFF 668

Query: 673 SEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNK 732
           SEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNK
Sbjct: 669 SEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNK 728

Query: 733 VTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGK 792
           VTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGK
Sbjct: 729 VTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGK 788

Query: 793 AVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPP 852
           AVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPP
Sbjct: 789 AVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPP 848

Query: 853 TDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQRE 912
           TDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQRE
Sbjct: 849 TDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQRE 908

Query: 913 AWVSNDTYWELRKDPGFSKVDSPVLW 938
           AWVSNDTYWELRKDPGFSKVDSPVLW
Sbjct: 909 AWVSNDTYWELRKDPGFSKVDSPVLW 934


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 518/918 (56%), Positives = 665/918 (72%), Gaps = 49/918 (5%)

Query: 30  VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83
           VS++L+ P     S         DSWE++EGL+      Q+P   +GF+LKKRKWPLKGW
Sbjct: 10  VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69

Query: 84  HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143
           HKRFF LD G+LKY+K+  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 70  HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129

Query: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203
           S++ FD WVSKLRHHR+YRQNEI   P + + H F  ++  +SS     S+   K   +S
Sbjct: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186

Query: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263
              Q+     +++  +C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245

Query: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323
           L RT SAP    +Q    +  KK+KR  RRWR++++ KD K  LQ   P  G        
Sbjct: 246 LHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSG-------- 297

Query: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383
                             PVRLHSSNPNL + ++F    ++ +D  E+S++++K+QE+ C
Sbjct: 298 ------------------PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 337

Query: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443
            IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+  L+ +LS AL QN +L+ 
Sbjct: 338 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALSSALAQNTDLKE 396

Query: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIH--VSLPLSQQVANESRLSMSESVSEFFD 501
           RL RIH+ES++ D   S  +  S D   E+     +  L  Q++NESRLS+++S+SEFFD
Sbjct: 397 RLRRIHAESLLLD---SPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEFFD 453

Query: 502 AQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRR 560
           AQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ L   L  G   ++ RR
Sbjct: 454 AQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRR 513

Query: 561 ACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKAS 620
            CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA+
Sbjct: 514 TCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAA 573

Query: 621 ETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHP 680
           +   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHP
Sbjct: 574 QIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHP 633

Query: 681 PISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNI 740
           PISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNI
Sbjct: 634 PISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNI 693

Query: 741 LSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGK 800
           LSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++G V D+ GKAV+RLFGK
Sbjct: 694 LSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGK 753

Query: 801 WHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPD 860
           WHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+DP  K LLPPTD RFRPD
Sbjct: 754 WHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPD 813

Query: 861 QRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTY 920
           QRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+K  D    ++WVSN TY
Sbjct: 814 QRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTY 869

Query: 921 WELRKDPGFSKVDSPVLW 938
            ELRKD GFSK+D PVLW
Sbjct: 870 LELRKDLGFSKLDHPVLW 887


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score =  997 bits (2577), Expect = 0.0
 Identities = 506/916 (55%), Positives = 647/916 (70%), Gaps = 81/916 (8%)

Query: 30  VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83
           VS++L+ P     S         DSWE++EGL+      Q+P   +GF+LKKRKWPLKGW
Sbjct: 10  VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69

Query: 84  HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143
           HKRFF LD G+LKY+K+  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 70  HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129

Query: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203
           S++ FD WVSKLRHHR+YRQNEI   P + + H F  ++  +SS     S+   K   +S
Sbjct: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186

Query: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263
              Q+     +++  +C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245

Query: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323
           L RT SAP    +Q    +  KK+KR  RRWR++++ KD K  LQ   P  G        
Sbjct: 246 LHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSG-------- 297

Query: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383
                             PVRLHSSNPNL + ++F    ++ +D  E+S++++K+QE+ C
Sbjct: 298 ------------------PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 337

Query: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443
            IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+  L+ +LS           
Sbjct: 338 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALS----------- 385

Query: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQ 503
                 SE+             S DE    +H       Q++NESRLS+++S+SEFFDAQ
Sbjct: 386 ------SEN-------------SRDENRALVH-------QLSNESRLSITDSLSEFFDAQ 419

Query: 504 EVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRRAC 562
           EVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ L   L  G   ++ RR C
Sbjct: 420 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 479

Query: 563 LPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET 622
           LPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA++ 
Sbjct: 480 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 539

Query: 623 DDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPI 682
             P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHPPI
Sbjct: 540 PSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPI 599

Query: 683 SACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILS 742
           SACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNILS
Sbjct: 600 SACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILS 659

Query: 743 GRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWH 802
           G+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++G V D+ GKAV+RLFGKWH
Sbjct: 660 GQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWH 719

Query: 803 EGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQR 862
           E +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+DP  K LLPPTD RFRPDQR
Sbjct: 720 ESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQR 779

Query: 863 FLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 922
           FLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+K  D    ++WVSN TY E
Sbjct: 780 FLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLE 835

Query: 923 LRKDPGFSKVDSPVLW 938
           LRKD GFSK+D PVLW
Sbjct: 836 LRKDLGFSKLDHPVLW 851


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score =  987 bits (2552), Expect = 0.0
 Identities = 505/918 (55%), Positives = 647/918 (70%), Gaps = 80/918 (8%)

Query: 30  VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83
           VS++L+ P     S         DSWE++EGL+      Q+P   +GF+LKKRKWPLKGW
Sbjct: 10  VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69

Query: 84  HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143
           HKRFF LD G+LKY+K+  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 70  HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129

Query: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203
           S++ FD WVSKLRHHR+YRQNEI   P + + H F  ++  +SS     S+   K   +S
Sbjct: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186

Query: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263
              Q+     +++  +C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245

Query: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323
           L                              RT S      IQ+ +              
Sbjct: 246 LH-----------------------------RTYSAPAINAIQVPK-------------- 262

Query: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383
                      PFS    PVRLHSSNPNL + ++F    ++ +D  E+S++++K+QE+ C
Sbjct: 263 -----------PFSG---PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 306

Query: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443
            IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+  L+ +LS AL QN +L+ 
Sbjct: 307 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALSSALAQNTDLKE 365

Query: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIH--VSLPLSQQVANESRLSMSESVSEFFD 501
           RL RIH+ES++ D   S  +  S D   E+     +  L  Q++NESRLS+++S+SEFFD
Sbjct: 366 RLRRIHAESLLLD---SPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEFFD 422

Query: 502 AQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRR 560
           AQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ L   L  G   ++ RR
Sbjct: 423 AQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRR 482

Query: 561 ACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKAS 620
            CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA+
Sbjct: 483 TCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAA 542

Query: 621 ETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHP 680
           +   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHP
Sbjct: 543 QIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHP 602

Query: 681 PISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNI 740
           PISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNI
Sbjct: 603 PISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNI 662

Query: 741 LSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGK 800
           LSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++G V D+ GKAV+RLFGK
Sbjct: 663 LSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGK 722

Query: 801 WHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPD 860
           WHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+DP  K LLPPTD RFRPD
Sbjct: 723 WHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPD 782

Query: 861 QRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTY 920
           QRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+K  D    ++WVSN TY
Sbjct: 783 QRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTY 838

Query: 921 WELRKDPGFSKVDSPVLW 938
            ELRKD GFSK+D PVLW
Sbjct: 839 LELRKDLGFSKLDHPVLW 856


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score =  951 bits (2457), Expect = 0.0
 Identities = 493/916 (53%), Positives = 629/916 (68%), Gaps = 112/916 (12%)

Query: 30  VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83
           VS++L+ P     S         DSWE++EGL+      Q+P   +GF+LKKRKWPLKGW
Sbjct: 10  VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69

Query: 84  HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143
           HKRFF LD G+LKY+K+  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 70  HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129

Query: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203
           S++ FD WVSKLRHHR+YRQNEI   P + + H F  ++  +SS     S+   K   +S
Sbjct: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186

Query: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263
              Q+     +++  +C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245

Query: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323
           L                              RT S      IQ+ +              
Sbjct: 246 LH-----------------------------RTYSAPAINAIQVPK-------------- 262

Query: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383
                      PFS    PVRLHSSNPNL + ++F    ++ +D  E+S++++K+QE+ C
Sbjct: 263 -----------PFSG---PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 306

Query: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443
            IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+  L+ +LS           
Sbjct: 307 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALS----------- 354

Query: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQ 503
                 SE+             S DE    +H       Q++NESRLS+++S+SEFFDAQ
Sbjct: 355 ------SEN-------------SRDENRALVH-------QLSNESRLSITDSLSEFFDAQ 388

Query: 504 EVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRRAC 562
           EVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ L   L  G   ++ RR C
Sbjct: 389 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 448

Query: 563 LPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET 622
           LPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA++ 
Sbjct: 449 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 508

Query: 623 DDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPI 682
             P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHPPI
Sbjct: 509 PSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPI 568

Query: 683 SACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILS 742
           SACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNILS
Sbjct: 569 SACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILS 628

Query: 743 GRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWH 802
           G+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++G V D+ GKAV+RLFGKWH
Sbjct: 629 GQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWH 688

Query: 803 EGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQR 862
           E +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+DP  K LLPPTD RFRPDQR
Sbjct: 689 ESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQR 748

Query: 863 FLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 922
           FLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+K  D    ++WVSN TY E
Sbjct: 749 FLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLE 804

Query: 923 LRKDPGFSKVDSPVLW 938
           LRKD GFSK+D PVLW
Sbjct: 805 LRKDLGFSKLDHPVLW 820


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score =  831 bits (2146), Expect = 0.0
 Identities = 442/915 (48%), Positives = 585/915 (63%), Gaps = 85/915 (9%)

Query: 28  PSVSRQLLEPEPVPLSKEADSWEIIEG--LKIGQTNVQKPDKHEGFMLKKRKWPLKGWHK 85
           P +       +P    + ++ WE++E   +++G   V  P++ EG +LKKRKWPLKGWHK
Sbjct: 9   PFLPESAQSSKPSSAQQASELWEVVEEPRVRLGTEGVM-PERQEGHLLKKRKWPLKGWHK 67

Query: 86  RFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQ 145
           R+FVL++G+L Y+    DI KGK+HGSIDV LSVMSI KKA+RIDLDTE++IYHLK+KSQ
Sbjct: 68  RYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQ 127

Query: 146 DWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFP 205
           D F +WV++LR HRL  + ++ R    ++ H       A+   AA  S + G + P    
Sbjct: 128 DLFQSWVAQLRAHRLAHRLDMPRGSLPSTAH--RKVPGAQLPTAATASALPG-LGP---- 180

Query: 206 WQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQ 265
                             + KV++WL+DS+ +DRC+ +L+ CQ  L EL +LLQ+LE L 
Sbjct: 181 ------------------REKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLH 222

Query: 266 RTQSAPNFTDMQANCV-DISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRRQ 324
           R  SAP     QA+   +  KK KR +R W T+S +KD  I         G+        
Sbjct: 223 RIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQSFAKDDTI---------GRVG------ 267

Query: 325 RLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCL 384
                              RLH S PNL   +E +        P    TDY  LQ  F  
Sbjct: 268 -------------------RLHGSVPNLSRYLESRDSSGTRGLP---PTDYAHLQRSFWA 305

Query: 385 IAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSR 444
           +AQKVHS L S   ++ +E+++L+ M     H     ++M     S  Q           
Sbjct: 306 LAQKVHSSLSSVLAALTMERDQLRDM-----HQGSELSRMGVSEASTGQ----------- 349

Query: 445 LNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQE 504
             R+HS S   D         +P+E          L+ Q++  S LS+++S +EFFDA E
Sbjct: 350 -RRLHSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQTSILSLADSHTEFFDACE 408

Query: 505 VLLSASSSENEASDDE-SYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACL 563
           VLLSASSSENE S++E S  S+++ ++SE+   +     R    G + G      RR CL
Sbjct: 409 VLLSASSSENEGSEEEESCTSEITTSLSEEMLDLR-GAERCQKGGCVPGRPMGPPRRRCL 467

Query: 564 PAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETD 623
           PA     ++++LWNILRNNIGKDLSKVSMPV+LNEPLNTLQ LCEE+EYS LLD+AS   
Sbjct: 468 PAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIA 527

Query: 624 DPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPIS 683
           DP ERMV +AAFAVS Y STY RAG KPFNPVLGETYEC R D+GFRF SEQVSHHPPIS
Sbjct: 528 DPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPIS 587

Query: 684 ACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSG 743
           ACH ES+NF FWQD++WKNKFWGKS+EI+PVGT+NV LP++GD++ WNKVT+CIHN+LSG
Sbjct: 588 ACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSG 647

Query: 744 RRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHE 803
           +RWIEHYGEV IRNT+ S C CK+TF K  YW+SN++EVQG V+ + G+ ++RLFGKWHE
Sbjct: 648 QRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVLHRLFGKWHE 707

Query: 804 GLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 863
           GLY G  P  +CIW+P SMP ++E  +GFT+FA+ELNEL   LK  LP TD R RPDQR+
Sbjct: 708 GLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRY 767

Query: 864 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWEL 923
           LEEGN++AA ++K+R+E+LQR RR+ MEENN+ H  +FF++  D++ +E WV+N+TYW L
Sbjct: 768 LEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEWWVTNNTYWRL 827

Query: 924 RKDPGFSKVDSPVLW 938
           R +PG+  +D  VLW
Sbjct: 828 RAEPGYGNMDGAVLW 842


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  295 bits (754), Expect = 2e-79
 Identities = 182/493 (36%), Positives = 257/493 (52%), Gaps = 59/493 (11%)

Query: 480 LSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVAD 539
           L Q +   S  +   S  EF+DA    LS S SE   S  E+     + +  E+   +  
Sbjct: 457 LEQSLVKGSPPASILSEDEFYDA----LSDSESERSLSRLEAV---TARSFEEEGEHLGS 509

Query: 540 NISRQILNGELTGG-AFRNG---RRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVE 595
              R     +  GG A  NG    R  LP+P    ++ ++W+ILR  IG +LSK++MPV 
Sbjct: 510 RKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVI 569

Query: 596 LNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPV 655
            NEPL+ LQ L E ME++ L+ KAS   DP ERM  VAAFAVS   S + R G KPFNP+
Sbjct: 570 FNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPL 628

Query: 656 LGETYECIREDKGFRFFSEQVSHHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILP 713
           LGETYE +R+D GFR  SEQVSHHPPISA H E  N  F+F   I  K KFWGKS+E  P
Sbjct: 629 LGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEP 688

Query: 714 VGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVN 773
            GT+ + L ++ + Y W   T C+HNI+ G+ WIE YG V I N K+    C L F    
Sbjct: 689 KGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTG-DKCVLNFKPCG 747

Query: 774 YWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLY--------------------------- 806
            +   +++V+G + D+  K +  L+GKW E LY                           
Sbjct: 748 LFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQM 807

Query: 807 ----------------CGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLL 850
                             + P +  +WR    P N    Y FT FA+ LNE+D  ++ ++
Sbjct: 808 STSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVI 867

Query: 851 PPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDA-N 909
           P TD R RPD R +E G ++ A+ EK+R+EE QR+ R+   ++  +   ++F +  +  N
Sbjct: 868 PKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYN 927

Query: 910 QREAWVSNDTYWE 922
             + W+ + +YW+
Sbjct: 928 GAQDWIYSGSYWD 940


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  289 bits (740), Expect = 7e-78
 Identities = 164/420 (39%), Positives = 230/420 (54%), Gaps = 51/420 (12%)

Query: 552 GGAFRNG---RRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 608
           G A  NG    R  LP+P    ++ ++W+ILR  IG +LSK++MPV  NEPL+ LQ L E
Sbjct: 10  GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTE 69

Query: 609 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKG 668
            ME++ L+ KAS   DP ERM  VAAFAVS   S + R G KPFNP+LGETYE +R+D G
Sbjct: 70  YMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLG 128

Query: 669 FRFFSEQVSHHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 726
           FR  SEQVSHHPPISA H E  N  F+F   I  K KFWGKS+E  P GT+ + L ++ +
Sbjct: 129 FRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNE 188

Query: 727 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVV 786
            Y W   T C+HNI+ G+ WIE YG V I N K+    C L F     +   +++V+G +
Sbjct: 189 AYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTG-DKCVLNFKPCGLFGKELHKVEGYI 247

Query: 787 IDQEGKAVYRLFGKWHEGLY---------------------------------------- 806
            D+  K +  L+GKW E LY                                        
Sbjct: 248 QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPD 307

Query: 807 ---CGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 863
                + P +  +WR    P N    Y FT FA+ LNE+D  ++ ++P TD R RPD R 
Sbjct: 308 SESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRA 367

Query: 864 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDA-NQREAWVSNDTYWE 922
           +E G ++ A+ EK+R+EE QR+ R+   ++  +   ++F +  +  N  + W+ + +YW+
Sbjct: 368 MENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWD 427


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  285 bits (728), Expect = 2e-76
 Identities = 171/453 (37%), Positives = 235/453 (51%), Gaps = 57/453 (12%)

Query: 498 EFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRN 557
           EFFDA     S +SS  E S+    ++ + D  +  N  +     R      +       
Sbjct: 6   EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGI------Q 58

Query: 558 GRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLD 617
             R  LPAP    S+ ++W IL+  +G +LSK++MP+  NEPL+ LQ + E ME+  L+ 
Sbjct: 59  KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 118

Query: 618 KASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVS 677
           +AS    P ERM  VAAFAVS   S + R G KPFNP+LGETYE IRED GFRF SEQVS
Sbjct: 119 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 177

Query: 678 HHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTT 735
           HHPPISA H E  N  F+F   I  K KFWGKS+E  P GT+ + L K+ + Y W   T 
Sbjct: 178 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 237

Query: 736 CIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVY 795
           C+HN++ G+ WIE YG V I N ++    C L F     +   +++V+G + D+  K ++
Sbjct: 238 CVHNVIIGKLWIEQYGTVEILNHRTG-HKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 296

Query: 796 RLFGKWHEGLY----------------------------------------------CGV 809
            ++GKW E L+                                                V
Sbjct: 297 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 356

Query: 810 APSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNL 869
            P +K +WR  + P N    Y FT F + LNEL+  ++  LPPTD R RPD R +E GN+
Sbjct: 357 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 416

Query: 870 EAAASEKQRVEELQRSRRRYMEENNLEHIPKFF 902
           + A+ EK+R+EE QR  RR   +   E   ++F
Sbjct: 417 DLASQEKERLEEKQREARRERAKEEAEWQTRWF 449


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  282 bits (721), Expect = 1e-75
 Identities = 158/391 (40%), Positives = 214/391 (54%), Gaps = 50/391 (12%)

Query: 560 RACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKA 619
           R  LPAP    S+ ++W IL+  +G +LSK++MP+  NEPL+ LQ + E ME+  L+ +A
Sbjct: 49  RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA 108

Query: 620 SETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHH 679
           S    P ERM  VAAFAVS   S + R G KPFNP+LGETYE IRED GFRF SEQVSHH
Sbjct: 109 SCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVSHH 167

Query: 680 PPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCI 737
           PPISA H E  N  F+F   I  K KFWGKS+E  P GT+ + L K+ + Y W   T C+
Sbjct: 168 PPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCV 227

Query: 738 HNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRL 797
           HN++ G+ WIE YG V I N ++    C L F     +   +++V+G + D+  K ++ +
Sbjct: 228 HNVIIGKLWIEQYGTVEILNHRTG-HKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMI 286

Query: 798 FGKWHEGLY----------------------------------------------CGVAP 811
           +GKW E L+                                                V P
Sbjct: 287 YGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIP 346

Query: 812 SAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEA 871
            +K +WR  + P N    Y FT F + LNEL+  ++  LPPTD R RPD R +E GN++ 
Sbjct: 347 GSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDL 406

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFF 902
           A+ EK+R+EE QR  RR   +   E   ++F
Sbjct: 407 ASQEKERLEEKQREARRERAKEEAEWQTRWF 437


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score =  271 bits (694), Expect = 2e-72
 Identities = 183/475 (38%), Positives = 268/475 (56%), Gaps = 53/475 (11%)

Query: 491 SMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGE- 549
           S  +  +E+FDA E   S  +   EA +D S  ++ S   S  + S ADN+    L+G  
Sbjct: 444 SEEDEDTEYFDAMEDSTSFITVITEAKED-SRKAEGSTGTSSVDWSSADNV----LDGAS 498

Query: 550 -LTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 608
            +  G+ +  RR  +P   P+ S +NLW+I++N IG++LS++ MPV  NEPL+ LQ L E
Sbjct: 499 LVPKGSSKVKRRVRIPNK-PNYS-LNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTE 556

Query: 609 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR-EDK 667
           ++EY  LLDKA       E+M LVAAF+VS Y +T  R  +KPFNP+LGET+E  R +D 
Sbjct: 557 DLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDM 615

Query: 668 GFRFFSEQVSHHPPISACHCESKN-FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 726
           G R   EQVSHHPP +A +  SK+ +  WQ+I   +KF GK + I+P+G +++     G+
Sbjct: 616 GLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGN 675

Query: 727 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSN-MNEVQGV 785
           +YVW K T+ +HNI+ G+ WI+  G++ I N K++   C+L F+  +Y++     +V GV
Sbjct: 676 HYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTN-DRCQLKFLPYSYFSKEAARKVTGV 734

Query: 786 VIDQEGKAVYRLFGKWHEGLYCGVAP--------------------SAKCIWRPGSMPTN 825
           V D +GKA Y L G W E + C                        SAK +W+   +P N
Sbjct: 735 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN 794

Query: 826 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQR- 884
            E  Y F+  A+ LNE +    + + PTD+R RPDQR +E+G  + A +EKQR+EE QR 
Sbjct: 795 AENMYYFSELALTLNEHE----EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRL 850

Query: 885 SRRRYME----------ENNLE---HIPKFFKKVIDANQRE-AWVSNDTYWELRK 925
           SRRR +E          E   E   + P +F+K +D    E A V    YWE ++
Sbjct: 851 SRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKE 905



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 3/90 (3%)

Query: 66  DKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKK 125
           D  EG++LK   + LKG+ +R+FVL NG+L Y +   ++      G+I++  + +  +  
Sbjct: 183 DSFEGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQGEMAH-TCRGTINLSTAHIDTEDS 240

Query: 126 ARRIDLDTEEHIYHLKVKSQDWFDAWVSKL 155
              I L +    YHLK  S+     W++ L
Sbjct: 241 C-GILLTSGARSYHLKASSEVDRQQWITAL 269


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  268 bits (685), Expect = 2e-71
 Identities = 193/596 (32%), Positives = 299/596 (50%), Gaps = 75/596 (12%)

Query: 368 PLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARL 427
           P ES+    ++ E   L     ++++ +  + + + +   K+      + +    Q  RL
Sbjct: 248 PAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERD---QRIRL 304

Query: 428 RQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANE 487
            ++L Q   Q+  L                     ++P    A    +V     Q  + +
Sbjct: 305 EETLEQLAKQHNHLERAFR-------------GATVLP----ANTPGNVGSGKDQCCSGK 347

Query: 488 SRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILN 547
             +S  +  +EFFDA E++    +  ++ +   S IS  S +IS D     +    Q+  
Sbjct: 348 GDMSDEDDENEFFDAPEIITMPENLGHKRTG--SNISGASSDISLD-----EQYKHQL-- 398

Query: 548 GELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLC 607
            E T    +  +R  +P   P+ S +NLW+I++N IGK+LSK+ MPV  NEPL+ LQ L 
Sbjct: 399 -EET----KKEKRTRIPYK-PNYS-LNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLT 451

Query: 608 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR-ED 666
           E++EY ELLD+A++ ++  E++  VAAF VS Y +T FR  SKPFNP+LGET+E  R E+
Sbjct: 452 EDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRT-SKPFNPLLGETFELDRLEE 510

Query: 667 KGFRFFSEQVSHHPPISACHCESKN-FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYG 725
            G+R   EQVSHHPP +A H ESKN +   Q+I+  +KF GK + I+P+GT++ +    G
Sbjct: 511 NGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATG 570

Query: 726 DYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNM-NEVQG 784
            +Y W KVTT +HNI+ G+ WI+  GE+ I N K+    C L FV  +Y++ ++  +V G
Sbjct: 571 HHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTG-DKCNLKFVPYSYFSRDVARKVTG 629

Query: 785 VVIDQEGKAVYRLFGKWHEGLYC-GVAP------------------SAKCIWRPGSMPTN 825
            V D  GK  + L G W E + C  V P                  S   +W+   +P N
Sbjct: 630 EVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKN 689

Query: 826 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 885
            E  Y F+  A+ LN      +    PTD+R RPDQR +E G  + A +EKQR+EE QR 
Sbjct: 690 AENMYYFSELALTLN----AWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRL 745

Query: 886 RRRYME-------ENNLEHIPK----FFKKVIDANQREAWVSNDTYWELRKDPGFS 930
            R+  E       E+   + P     F +K     +    +    YWE ++   +S
Sbjct: 746 SRKKREAEAMKATEDGTPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWS 801



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 24/87 (27%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 69  EGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARR 128
           EG++ K   + +KG+ +R+FVL NG+L Y ++  ++ +    G+I++  + ++++     
Sbjct: 92  EGWLFKWTNY-IKGYQRRWFVLSNGLLSYYRSKAEM-RHTCRGTINLATANITVEDSCNF 149

Query: 129 IDLDTEEHIYHLKVKSQDWFDAWVSKL 155
           I  +     YHLK  S+     WV+ L
Sbjct: 150 IISNGGAQTYHLKASSEVERQRWVTAL 176


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 507 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 559
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 290 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 344

Query: 560 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 607
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 345 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 404

Query: 608 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 663
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 405 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 463

Query: 664 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 721
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 464 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 523

Query: 722 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 779
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 524 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 582

Query: 780 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 837
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 583 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 637

Query: 838 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 897
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 638 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 691

Query: 898 IPKFF 902
            P+ F
Sbjct: 692 KPQLF 696


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 507 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 559
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 222 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 276

Query: 560 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 607
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 277 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 336

Query: 608 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 663
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 337 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 395

Query: 664 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 721
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455

Query: 722 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 779
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 514

Query: 780 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 837
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 515 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 569

Query: 838 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 897
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 570 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 623

Query: 898 IPKFF 902
            P+ F
Sbjct: 624 KPQLF 628


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 507 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 559
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 222 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 276

Query: 560 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 607
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 277 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 336

Query: 608 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 663
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 337 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 395

Query: 664 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 721
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455

Query: 722 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 779
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 514

Query: 780 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 837
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 515 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 569

Query: 838 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 897
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 570 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 623

Query: 898 IPKFF 902
            P+ F
Sbjct: 624 KPQLF 628


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 98/394 (24%), Positives = 164/394 (41%), Gaps = 66/394 (16%)

Query: 569 DTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYER 628
           D  +I L  I +  +G DL+KV +P  + E  + L+   + M + +LL   +    P ER
Sbjct: 395 DQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEER 454

Query: 629 MVLVAAFAVSGYCSTYFRA-GSKPFNPVLGETYECIRE---------------------- 665
           ++    + ++ +      A   KP+NP++GET+ C  E                      
Sbjct: 455 VICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEH 514

Query: 666 ------DKGF--RFFSEQVSHHPPISA--CHCESKNFVFWQDIRWKNKFWGKSMEILPVG 715
                  K +  RF +EQVSHHPPIS   C CE K       +  K+KF G S+ +  +G
Sbjct: 515 PMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIG 574

Query: 716 TLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW 775
              + L ++G+ YV+   +    +IL+   W+E  G+V+I   K+      +   K  Y 
Sbjct: 575 EGVLRLLEHGEEYVFTLPSAYARSILT-IPWVELGGKVSINCAKTGYSATVIFHTKPFYG 633

Query: 776 NSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRF 835
                    V  +     V +  G+W+                 G++   Y    G T+ 
Sbjct: 634 GKVHRVTAEVKHNPTNTIVCKAHGEWN-----------------GTLEFTYN--NGETK- 673

Query: 836 AIELNELDPVLKDLLP-----PTDAR--FRPDQRFLEEGNLEAAASEKQRVEELQRSRRR 888
            I+   L    K + P     P ++R  +R   R+L  G+++AA  +K+ +EE QR   R
Sbjct: 674 VIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEER 733

Query: 889 YMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 922
             E       PK+F       + + WV  +  W+
Sbjct: 734 KRENLRTPWKPKYF-----IQEGDGWVYFNPLWK 762



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 46/205 (22%), Positives = 85/205 (41%), Gaps = 22/205 (10%)

Query: 80  LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARR--IDLDTEE 135
           L+GW  R+FVLD   G+L+Y       +  K  G + +  +++S+  +A    +      
Sbjct: 88  LQGWQNRYFVLDFEAGILQYF-VNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANG 146

Query: 136 HIYHLKVKSQDWFDAWVSKLR---HHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV 192
            ++ L+         WV++LR    + +   ++   S R  S  + P  +   +SP +  
Sbjct: 147 EMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQR 206

Query: 193 SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAE----DLAHCQ 248
            +  G       P    +    S PA     +S+ +  L +  EM    E    +L H  
Sbjct: 207 HLSVGA------PGVVTITHHKS-PAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAI 259

Query: 249 SNLV---ELSKLLQNLEILQRTQSA 270
            +L     L+ L Q+L +L+ T +A
Sbjct: 260 ESLPGSGPLTALDQDLLLLKATSAA 284


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 583

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 641

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 642 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 683

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 684 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 725



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 77  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155
             ++  +H + +  D  + W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 593

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 594 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 651

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 652 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 693

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 694 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 735



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 77  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155
             ++  +H + +  D  + W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 570

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 571 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 628

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 629 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 670

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 671 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 712



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 77  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155
             ++  +H + +  D  + W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 354

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 355 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 414

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 415 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 473

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 474 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 531

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 532 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 573

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 574 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 615


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 122 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 181

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 182 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 241

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 242 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 299

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 300 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 359

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 360 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 418

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 419 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 476

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 477 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 518

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 519 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 560


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 405

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 406 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 463

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 464 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 505

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 506 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 547


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 405

Query: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 406 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 463

Query: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 464 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 505

Query: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 506 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 547


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/438 (24%), Positives = 183/438 (41%), Gaps = 37/438 (8%)

Query: 489 RLSMSESVSEFFDAQEVLLSASSSENEASDDES--------YISDVSDNISEDNTSVADN 540
           +L+ SE   + F  Q++    S  EN+   DES          SD   +  +D++ +   
Sbjct: 268 QLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPE 327

Query: 541 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNIN---LWNILRN-NIGKDLSKVSMPVEL 596
               +     T  +      A   +     S  N   +W +L+    G DLSKV +P  +
Sbjct: 328 PVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFI 387

Query: 597 NEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVL 656
            EP + L  L +   +++ L +A+  ++PY R+  V  + +SG+     +   KP+NP+L
Sbjct: 388 LEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKP-KGLKKPYNPIL 446

Query: 657 GETYECI----REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSME 710
           GET+ C+    R +    + +EQVSHHPPISA +  ++   F     I  K+KF+G S+ 
Sbjct: 447 GETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLS 506

Query: 711 ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFV 770
            +  G   +     G+ YV          IL G   +E  G V I   K+      L F 
Sbjct: 507 AILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI-LEFK 565

Query: 771 KVNYWNSN--MNEVQGVVIDQEGKAVY-RLFGKWHEGLYC--GVAPSAKCIWRPGSMPTN 825
              +  S+  +N++ G +  + GK V   L G W   ++       +++  W P      
Sbjct: 566 LKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQ 623

Query: 826 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 885
           + L     R  ++  E      + L      ++   R +   +   A  EK  +EE QR 
Sbjct: 624 WRL----IRHTVKFEEQGDFESEKL------WQRVTRAINAKDQTEATQEKYVLEEAQRQ 673

Query: 886 RRRYMEENNLEHIPKFFK 903
             R  +  N E   K F+
Sbjct: 674 AARDRKTKNEEWSCKLFE 691


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/438 (24%), Positives = 183/438 (41%), Gaps = 37/438 (8%)

Query: 489 RLSMSESVSEFFDAQEVLLSASSSENEASDDES--------YISDVSDNISEDNTSVADN 540
           +L+ SE   + F  Q++    S  EN+   DES          SD   +  +D++ +   
Sbjct: 310 QLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPE 369

Query: 541 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNIN---LWNILRN-NIGKDLSKVSMPVEL 596
               +     T  +      A   +     S  N   +W +L+    G DLSKV +P  +
Sbjct: 370 PVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFI 429

Query: 597 NEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVL 656
            EP + L  L +   +++ L +A+  ++PY R+  V  + +SG+     +   KP+NP+L
Sbjct: 430 LEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKP-KGLKKPYNPIL 488

Query: 657 GETYECI----REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSME 710
           GET+ C+    R +    + +EQVSHHPPISA +  ++   F     I  K+KF+G S+ 
Sbjct: 489 GETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLS 548

Query: 711 ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFV 770
            +  G   +     G+ YV          IL G   +E  G V I   K+      L F 
Sbjct: 549 AILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI-LEFK 607

Query: 771 KVNYWNSN--MNEVQGVVIDQEGKAVY-RLFGKWHEGLYC--GVAPSAKCIWRPGSMPTN 825
              +  S+  +N++ G +  + GK V   L G W   ++       +++  W P      
Sbjct: 608 LKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQ 665

Query: 826 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 885
           + L     R  ++  E      + L      ++   R +   +   A  EK  +EE QR 
Sbjct: 666 WRL----IRHTVKFEEQGDFESEKL------WQRVTRAINAKDQTEATQEKYVLEEAQRQ 715

Query: 886 RRRYMEENNLEHIPKFFK 903
             R  +  N E   K F+
Sbjct: 716 AARDRKTKNEEWSCKLFE 733


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 81/383 (21%), Positives = 151/383 (39%), Gaps = 64/383 (16%)

Query: 583 IGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCS 642
           +G DL++V +P  + E  + L+   + M + +L    +      +RM+    + ++ +  
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438

Query: 643 TYFRA-GSKPFNPVLGETYECI------------------------------------RE 665
               A   KP+NP++GET+ C                                      +
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498

Query: 666 DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 723
               RF +EQVSHHPP+S     C  +       +  K+KF G S+ +  VG   + L +
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558

Query: 724 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 783
           +G+ Y ++       +IL+   W+E  G+V++   K+      +TF    ++   ++ V 
Sbjct: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSVNCAKTGYS-ASITFHTKPFYGGKLHRVT 616

Query: 784 GVVIDQ-EGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNEL 842
             V        V R+ G+W+  L               +       Y   T+ A+    +
Sbjct: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663

Query: 843 DPVLKDLLPPTDAR--FRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK 900
            P+ K    P ++R  ++     L E  ++ A   K  +EE QR+  R+  E       K
Sbjct: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721

Query: 901 FFKKVIDANQREAWVSNDTYWEL 923
           +F K     + + WV +   W++
Sbjct: 722 YFIK-----EGDGWVYHKPLWKI 739


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 64  KPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLD-IQKGKVHGSIDVGLSVMSI 122
           +P +  G++LK     +K W +R+FVL  G L Y K+P D I+K + H  +    S++  
Sbjct: 702 EPLEKSGYLLKM-SGKVKSWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRG 760

Query: 123 KKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRH 157
             K + + L TE+H Y+L   S +  + W+  L++
Sbjct: 761 DNK-QTVQLTTEKHTYYLTADSPNILEEWIKVLQN 794


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 28/105 (26%), Positives = 55/105 (52%), Gaps = 7/105 (6%)

Query: 53  EGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGS 112
           +GL +G  +++K     G++LK     +K W +R+FVL  G + Y K+P D+ + K  G 
Sbjct: 570 DGLGLGGESLEK----SGYLLKMGS-QVKTWKRRWFVLRQGQIMYYKSPSDVIR-KPQGQ 623

Query: 113 IDVGLSVMSIK-KKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLR 156
           +D+      ++ + ++   L +E+  Y+L   S    + W+  L+
Sbjct: 624 VDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQ 668


>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
           sapiens]
          Length = 574

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 51/216 (23%), Positives = 92/216 (42%), Gaps = 32/216 (14%)

Query: 24  SSTEPSVSRQLLEPEPV--PLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLK---KRKW 78
           S   PS SR+L  P+P   PLS    S       + G         + G++ K   ++K 
Sbjct: 2   SLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHV------LYSGWLRKSPPEKKL 55

Query: 79  PLKGWHKRFFVLDNG-------MLKY-----SKAPLDIQKGKVHGSIDVGLSVMSIKKKA 126
            L  W KR+F+L  G       +L+Y     SK PL      +   +DV +++   KK+ 
Sbjct: 56  RLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEI 115

Query: 127 RR---IDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTST 183
           ++    D+ T E  ++L  ++++  + WV  +     +RQ E      + S        +
Sbjct: 116 QKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEESTGFLGNIS-SASHGLCS 174

Query: 184 AESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 219
           + + P+ +   +  + +P S P     P S+ +P T
Sbjct: 175 SPAEPSCSHQHLPQEQEPTSEP-----PVSHCVPPT 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,546,739
Number of Sequences: 37866
Number of extensions: 1672683
Number of successful extensions: 6203
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 5898
Number of HSP's gapped (non-prelim): 288
length of query: 938
length of database: 18,247,518
effective HSP length: 112
effective length of query: 826
effective length of database: 14,006,526
effective search space: 11569390476
effective search space used: 11569390476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.