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Search of human proteins with 114842396
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114842396 ankyrin-repeat and fibronectin type III domain
containing 1 [Homo sapiens]
(763 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114842396 ankyrin-repeat and fibronectin type III domain cont... 1535 0.0
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 46 1e-04
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 46 1e-04
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 46 1e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 45 3e-04
gi|110349717 titin isoform novex-2 [Homo sapiens] 45 3e-04
gi|110349713 titin isoform novex-1 [Homo sapiens] 45 3e-04
gi|110349715 titin isoform N2-B [Homo sapiens] 45 3e-04
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 42 0.003
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 40 0.008
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 40 0.008
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 40 0.008
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 39 0.018
gi|28373124 contactin 4 isoform b precursor [Homo sapiens] 39 0.018
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 39 0.018
gi|71274109 nuclear factor of kappa light polypeptide gene enhan... 39 0.024
gi|21389501 coiled-coil domain containing 52 [Homo sapiens] 39 0.024
gi|55956914 myosin binding protein H [Homo sapiens] 39 0.024
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 38 0.040
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 38 0.040
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 38 0.040
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 38 0.040
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 37 0.052
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 37 0.052
gi|118150656 ankyrin repeat domain 7 [Homo sapiens] 37 0.069
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 37 0.069
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 37 0.069
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 37 0.090
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 37 0.090
gi|4827022 contactin 2 precursor [Homo sapiens] 37 0.090
>gi|114842396 ankyrin-repeat and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 763
Score = 1535 bits (3973), Expect = 0.0
Identities = 763/763 (100%), Positives = 763/763 (100%)
Query: 1 MEASLTRRLLFKDRHFTCSKIIGRRFACFAQRLSHRRKQSQCDLLNESTGQLPTTCSSAA 60
MEASLTRRLLFKDRHFTCSKIIGRRFACFAQRLSHRRKQSQCDLLNESTGQLPTTCSSAA
Sbjct: 1 MEASLTRRLLFKDRHFTCSKIIGRRFACFAQRLSHRRKQSQCDLLNESTGQLPTTCSSAA 60
Query: 61 SNSINWNCRVKMTQQMQNLHLCQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFR 120
SNSINWNCRVKMTQQMQNLHLCQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFR
Sbjct: 61 SNSINWNCRVKMTQQMQNLHLCQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFR 120
Query: 121 TRTDRLSLRKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDI 180
TRTDRLSLRKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDI
Sbjct: 121 TRTDRLSLRKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDI 180
Query: 181 AIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLD 240
AIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLD
Sbjct: 181 AIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLD 240
Query: 241 NTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAA 300
NTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAA
Sbjct: 241 NTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAA 300
Query: 301 VVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQT 360
VVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQT
Sbjct: 301 VVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQT 360
Query: 361 TTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRALHQHYSCRESTKLQTTGRKQSVS 420
TTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRALHQHYSCRESTKLQTTGRKQSVS
Sbjct: 361 TTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRALHQHYSCRESTKLQTTGRKQSVS 420
Query: 421 RSLKHLFHSSNKFVKTLKRGLYIAVIFYYKDNILVTNEDQVPIVEIDDSHTSSITQDFLW 480
RSLKHLFHSSNKFVKTLKRGLYIAVIFYYKDNILVTNEDQVPIVEIDDSHTSSITQDFLW
Sbjct: 421 RSLKHLFHSSNKFVKTLKRGLYIAVIFYYKDNILVTNEDQVPIVEIDDSHTSSITQDFLW 480
Query: 481 FTKLSCMWEDIRWLRQSIPISSSSSTVLQTRQKMLAATAQLQNLLGTHNLGRVYYEPIKD 540
FTKLSCMWEDIRWLRQSIPISSSSSTVLQTRQKMLAATAQLQNLLGTHNLGRVYYEPIKD
Sbjct: 481 FTKLSCMWEDIRWLRQSIPISSSSSTVLQTRQKMLAATAQLQNLLGTHNLGRVYYEPIKD 540
Query: 541 RHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYH 600
RHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYH
Sbjct: 541 RHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYH 600
Query: 601 KRSHQRLFPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENNNISREEWEWIQKLS 660
KRSHQRLFPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENNNISREEWEWIQKLS
Sbjct: 601 KRSHQRLFPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENNNISREEWEWIQKLS 660
Query: 661 GSESMESVDHTSDCPMQLFFYELQMAVKALLQQINIPLHQARNFRLYTQEVLEMGHNVSF 720
GSESMESVDHTSDCPMQLFFYELQMAVKALLQQINIPLHQARNFRLYTQEVLEMGHNVSF
Sbjct: 661 GSESMESVDHTSDCPMQLFFYELQMAVKALLQQINIPLHQARNFRLYTQEVLEMGHNVSF 720
Query: 721 LLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT 763
LLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT
Sbjct: 721 LLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT 763
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/182 (25%), Positives = 72/182 (39%), Gaps = 22/182 (12%)
Query: 197 GARESPHFVSLESRAMHLNTLVQEAQE---RVSE-LSAQVENEGFTLDNTEKEKQLKA-- 250
GA ++P+ + SR +H N L + RV + E+E LD+ +L
Sbjct: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
Query: 251 ----WEWRYRLYRRMKTG--------FEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
+E + Y G H P P + V SST +S+ EP N
Sbjct: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETN 1247
Query: 299 AAVVTRYKVEWSMSEDFSPLAG---EIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGW 355
+ T Y+V + + D + G ++++DN + I L Q Y V A N GW
Sbjct: 1248 GEI-TAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
Query: 356 GP 357
GP
Sbjct: 1307 GP 1308
Score = 33.1 bits (74), Expect = 0.99
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 1/87 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P + S SL +S++ P N +V Y V M++ P + +
Sbjct: 1624 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVG-YLVTCEMAQGGGPATAFRVDGDSPES 1682
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R T+ GL+ Y +V A +G+GP
Sbjct: 1683 RLTVPGLSENVPYKFKVQARTTEGFGP 1709
Score = 32.7 bits (73), Expect = 1.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 10/92 (10%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNL 327
A P+ PT + TSL VS+QEP + Y VE+ + GE+ N+
Sbjct: 1508 AGVPDTPTRLVFSALGPTSLRVSWQEPRCERP--LQGYSVEYQLLN-----GGELHRLNI 1560
Query: 328 QTLRCT---ITGLTMGQQYFVQVSAYNMKGWG 356
T + L Y +V A + +GWG
Sbjct: 1561 PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG 1592
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/182 (25%), Positives = 72/182 (39%), Gaps = 22/182 (12%)
Query: 197 GARESPHFVSLESRAMHLNTLVQEAQE---RVSE-LSAQVENEGFTLDNTEKEKQLKA-- 250
GA ++P+ + SR +H N L + RV + E+E LD+ +L
Sbjct: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
Query: 251 ----WEWRYRLYRRMKTG--------FEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
+E + Y G H P P + V SST +S+ EP N
Sbjct: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETN 1247
Query: 299 AAVVTRYKVEWSMSEDFSPLAG---EIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGW 355
+ T Y+V + + D + G ++++DN + I L Q Y V A N GW
Sbjct: 1248 GEI-TAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
Query: 356 GP 357
GP
Sbjct: 1307 GP 1308
Score = 33.5 bits (75), Expect = 0.76
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 19/168 (11%)
Query: 197 GARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYR 256
G+ S H ++ S A + L RV S+ + + +L +E R
Sbjct: 1453 GSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTL----PR 1508
Query: 257 LYRRMKTGFEH-----ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM 311
Y + + H A P+ PT + TSL VS+QEP + Y VE+ +
Sbjct: 1509 DYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP--LQGYSVEYQL 1566
Query: 312 SEDFSPLAGEIIMDNLQTLRCT---ITGLTMGQQYFVQVSAYNMKGWG 356
GE+ N+ T + L Y +V A + +GWG
Sbjct: 1567 LN-----GGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG 1609
Score = 33.1 bits (74), Expect = 0.99
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 1/87 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P + S SL +S++ P N +V Y V M++ P + +
Sbjct: 1641 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVG-YLVTCEMAQGGGPATAFRVDGDSPES 1699
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R T+ GL+ Y +V A +G+GP
Sbjct: 1700 RLTVPGLSENVPYKFKVQARTTEGFGP 1726
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/182 (25%), Positives = 72/182 (39%), Gaps = 22/182 (12%)
Query: 197 GARESPHFVSLESRAMHLNTLVQEAQE---RVSE-LSAQVENEGFTLDNTEKEKQLKA-- 250
GA ++P+ + SR +H N L + RV + E+E LD+ +L
Sbjct: 1128 GAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLY 1187
Query: 251 ----WEWRYRLYRRMKTG--------FEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
+E + Y G H P P + V SST +S+ EP N
Sbjct: 1188 PYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETN 1247
Query: 299 AAVVTRYKVEWSMSEDFSPLAG---EIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGW 355
+ T Y+V + + D + G ++++DN + I L Q Y V A N GW
Sbjct: 1248 GEI-TAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGW 1306
Query: 356 GP 357
GP
Sbjct: 1307 GP 1308
Score = 33.5 bits (75), Expect = 0.76
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 19/168 (11%)
Query: 197 GARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYR 256
G+ S H ++ S A + L RV S+ + + +L +E R
Sbjct: 1383 GSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTL----PR 1438
Query: 257 LYRRMKTGFEH-----ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM 311
Y + + H A P+ PT + TSL VS+QEP + Y VE+ +
Sbjct: 1439 DYSTLTSVSSHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP--LQGYSVEYQL 1496
Query: 312 SEDFSPLAGEIIMDNLQTLRCT---ITGLTMGQQYFVQVSAYNMKGWG 356
GE+ N+ T + L Y +V A + +GWG
Sbjct: 1497 LN-----GGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWG 1539
Score = 33.1 bits (74), Expect = 0.99
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 1/87 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P + S SL +S++ P N +V Y V M++ P + +
Sbjct: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVG-YLVTCEMAQGGGPATAFRVDGDSPES 1629
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R T+ GL+ Y +V A +G+GP
Sbjct: 1630 RLTVPGLSENVPYKFKVQARTTEGFGP 1656
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.1 bits (105), Expect = 3e-04
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 11/91 (12%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P P N ++ TS +S+++++ +P+ + +T Y VE ++ E+ +P AG
Sbjct: 21756 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG----- 21810
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWG 356
L+ TITGLT Q+Y +++ A N +G G
Sbjct: 21811 -LKATSYTITGLTENQEYKIRIYAMNSEGLG 21840
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 23/160 (14%)
Query: 252 EWRYRLYRRMKTGF-------------EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
E+ YR+Y G + P P+ ++ + T++T+++ +PL
Sbjct: 26052 EYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDG 26111
Query: 299 AAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-P 357
A +T Y VE+ S+D + + +L+ TI+GLT G +Y +V + N G P
Sbjct: 26112 GAPITGYTVEYKKSDDTD---WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDP 26168
Query: 358 AQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRA 397
+ ++ P A + EP SE+ + L+ + A
Sbjct: 26169 SDSSDPQIAKER------EEEPLFDIDSEMRKTLIVKAGA 26202
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 262 KTGFEHAR---APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
KT F + R +P P N+ + S+T+S++ PL A +T Y VE + +
Sbjct: 25187 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE---KRETTRK 25243
Query: 319 AGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
A I +N I L G Y+ +V A N G G PA+TT P S
Sbjct: 25244 AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS 25293
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P V L+ + + T+ +++P S + +T Y VE SE +S ++
Sbjct: 25296 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCT------QVK 25349
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TL TI+GLT G++Y +V+A N KG P Q P A
Sbjct: 25350 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIA 25388
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 281 VTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMG 340
VT +T+ TVS++ P+ + +T Y VE E S I + LRC +TGL G
Sbjct: 20583 VTKNTA-TVSWKRPVDDGGSEITGYHVE--RREKKSLRWVRAIKTPVSDLRCKVTGLQEG 20639
Query: 341 QQYFVQVSAYNMKGWGP 357
Y +VSA N G GP
Sbjct: 20640 STYEFRVSAENRAGIGP 20656
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
PE P V + ++ T++++ PL + + Y VE + S L ++ N+QTL
Sbjct: 22640 PEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVE---RRETSRLVWTVVDANVQTL 22694
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
C +T L G +Y ++ A N G G + P A
Sbjct: 22695 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 22730
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P PTN ++ T+ S+T+++ +P+ + + Y VE +++ +P G
Sbjct: 23920 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTG----- 23974
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSN 370
L+ R I+ LT Q+Y ++V A N G G A T+ P P +
Sbjct: 23975 -LRVTRFEISKLTEHQEYKIRVCALNKVGLGEA-TSVPGTVKPED 24017
Score = 38.9 bits (89), Expect = 0.018
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEII 323
E PE P ++ + + ++T+++ P + + Y +E + +E F ++
Sbjct: 16712 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH----KVT 16767
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSNWKDYDDR 377
DNL + + T+ GL G Y +VSA N+ G G P+ T P A P+ D+ D+
Sbjct: 16768 NDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK 16827
Query: 378 EPRHKGQSEVLEG 390
G++ L G
Sbjct: 16828 LTIRVGEAFALTG 16840
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P + LM + S+++S+++P + + Y VE S+ ++ A ++
Sbjct: 22049 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA------TVK 22102
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TITGL G++Y +VSA N KG P Q + P A
Sbjct: 22103 VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIA 22141
Score = 38.9 bits (89), Expect = 0.018
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P P V L S TS ++ +++P + V Y VE +E +S I+
Sbjct: 24210 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS------IVA 24263
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+ +TGL+ GQ+Y +V AYN KG
Sbjct: 24264 ESKVCNAVVTGLSSGQEYQFRVKAYNEKG 24292
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P+ P + + + S+++S+ +P + + +Y VE SE +S A
Sbjct: 23128 AEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA------ 23181
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+++L+ IT LT G++Y +V A N KG
Sbjct: 23182 RVKSLQAVITNLTQGEEYLFRVVAVNEKG 23210
Score = 36.6 bits (83), Expect = 0.090
Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 262 KTGFEHARAPEMPTNVC-LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
K+GF + R + P V L T T S+T+ + PL + +T Y VE + S
Sbjct: 20856 KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS 20915
Query: 319 AGEIIMDNLQTLRCT--ITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
+ +CT +TGL+ G +YF +V A N G G P +TT P AS
Sbjct: 20916 TA-----TTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKAS 20962
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P ++ + T +++ + +P + +T Y VE+ ++D+ I +
Sbjct: 17410 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW------IKFKTVT 17463
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L C +TGL G+ Y +V A N+ G G TT P
Sbjct: 17464 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 17498
Score = 35.4 bits (80), Expect = 0.20
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 25/141 (17%)
Query: 246 KQLKAWEWRYRLYRRMKTGF--------EHAR-------APEMPTNVCLMVTSSTSLTVS 290
K L+ E+ +R+ + K G E AR AP+ PT + + S+TV+
Sbjct: 16280 KLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT---VSSVTRNSMTVN 16336
Query: 291 FQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC----TITGLTMGQQYFVQ 346
++EP + VT Y +E M + S + D ++ + +TGL G Y +
Sbjct: 16337 WEEPEYDGGSPVTGYWLE--MKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 16394
Query: 347 VSAYNMKGWGPAQ-TTTPACA 366
V A N G GPA + PA A
Sbjct: 16395 VYAINAAGVGPASLPSDPATA 16415
Score = 35.0 bits (79), Expect = 0.26
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMD-NLQT 329
P P NV + + ++++++ P A +T Y +E D + + + M +
Sbjct: 13191 PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIEL---RDKTSIRWDTAMTVRAED 13247
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L T+T + GQ+Y +V A N G G TP
Sbjct: 13248 LSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 13281
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
+ AP P ++ +M + +++++++ +P + +T Y +E S+ ++ +
Sbjct: 20962 SEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT------ 21015
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
++ L C + LT G++Y QV A N G + + P
Sbjct: 21016 TVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRP 21053
Score = 34.3 bits (77), Expect = 0.44
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSE--DFSPLAGEII 323
E P PT V + TS T++++ + +P+ + Y +E ++ D+ + E
Sbjct: 28249 EPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC 28308
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTT 362
+ R T+T L G++Y +VSA N G G + T
Sbjct: 28309 VKT----RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT 28343
Score = 33.9 bits (76), Expect = 0.58
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 17/136 (12%)
Query: 234 NEGFTLDNTE-------KEKQLKAWEWRYRLYRRMKTG-------FEHARAPEMPTN-VC 278
+E T++NTE K Q K +Y++ G E P+ PT +
Sbjct: 30672 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 30731
Query: 279 LMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLT 338
+ S +S++ P + +T Y VE +++ + +++ + C I LT
Sbjct: 30732 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW--QLVSSAISVTTCRIVNLT 30789
Query: 339 MGQQYFVQVSAYNMKG 354
Y+ +VSA N G
Sbjct: 30790 ENAGYYFRVSAQNTFG 30805
Score = 33.5 bits (75), Expect = 0.76
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 25/131 (19%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED--FSPLAGEIIMDNLQTLRCTITGLTMG 340
++ S +++ P + +T Y +E S+ ++P+ + N T+ GL G
Sbjct: 16629 TNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-----ATVQGLIQG 16683
Query: 341 QQYFVQVSAYNMKGWGPAQTTTPA------CASPSNWKDYDDRE------------PRHK 382
+ YF +++A N G GP T+ A P +D + +E P++
Sbjct: 16684 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 16743
Query: 383 GQSEVLEGLLQ 393
G SE++ +L+
Sbjct: 16744 GGSEIINYVLE 16754
Score = 33.1 bits (74), Expect = 0.99
Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNL 327
+ P +P + ++ + +++T+++++PL + +T Y +E + + +++
Sbjct: 29632 SEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM--KVVTLKP 29689
Query: 328 QTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTT 362
L T+T L G+QY ++ A N KG P +T T
Sbjct: 29690 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVT 29725
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 279 LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITG 336
L VT+ T + T+S++ PL + +T + VE+ G I+ + T R
Sbjct: 18008 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQ----KGWSIVASDVTKRLIKAN 18063
Query: 337 LTMGQQYFVQVSAYNMKGWGPA-QTTTPACA 366
L +Y+ +V A N G GP +T TP A
Sbjct: 18064 LLANNEYYFRVCAENKVGVGPTIETKTPILA 18094
Score = 32.3 bits (72), Expect = 1.7
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 270 APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQT 329
A E P NV + S S+++S+Q+P + +T Y VE D N+
Sbjct: 26767 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS--FTNVTE 26824
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKG 354
+ I+GLT QY +V A N G
Sbjct: 26825 TQFIISGLTQNSQYEFRVFARNAVG 26849
Score = 32.0 bits (71), Expect = 2.2
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 269 RAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQ 328
+ P P + ++S S+ V + EP+S + V Y +E E S L ++ +
Sbjct: 22339 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE--RKERNSILWVKLNKTPIP 22396
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG 356
+ TGL G +Y +VSA N+ G G
Sbjct: 22397 QTKFKTTGLEEGVEYEFRVSAENIVGIG 22424
Score = 32.0 bits (71), Expect = 2.2
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQTLRCTITGLTMGQ 341
+ S+TV + P++ + ++ Y +E D L +++ + ++ R +TGLT
Sbjct: 27078 TKNSMTVVWSRPIADGGSDISGYFLE---KRDKKSLGWFKVLKETIRDTRQKVTGLTENS 27134
Query: 342 QYFVQVSAYNMKGWGP 357
Y +V A N G GP
Sbjct: 27135 DYQYRVCAVNAAGQGP 27150
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDN-LQTLRC 332
P+N+ + S+T+++ P S + + +Y +E E S ++I + R
Sbjct: 28160 PSNI-----TGNSITLTWARPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRF 28212
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGPAQ--TTTPACASPSN 370
+TGLT G +Y V A N G GPA + C P N
Sbjct: 28213 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 28252
Score = 31.6 bits (70), Expect = 2.9
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N+ + + +T+S+Q P + V Y VE +D ++
Sbjct: 17607 PTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVE---KQDTRKDTWGVVSSGSSKT 17661
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+ I L G +Y +V A N G GP +TP A
Sbjct: 17662 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA 17697
Score = 31.2 bits (69), Expect = 3.8
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Query: 282 TSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQTLRCTITGLTM 339
TSST++ + ++ P + Y V+ + + ++S ++I + + T+ +
Sbjct: 15013 TSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI----KVRQYTVKEIRE 15068
Query: 340 GQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRAL 398
G Y ++VSA N G GP T P + + + KG +++ G ++ A+
Sbjct: 15069 GADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAV 15127
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMS-EDFSPLAGEIIMD---N 326
P PTN ++ T+ S+T+ + +P+ A + Y VE D SP G +
Sbjct: 18497 PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQ 18556
Query: 327 LQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQ 359
L T+T L Q+Y +V A N G G PA+
Sbjct: 18557 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAE 18590
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P+ + + S+TV + EP+S + V Y +E M + S L + ++T
Sbjct: 26670 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLE--MKDRNSILWQKANKLVIRTT 26727
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSN 370
+T ++ G Y +V A N G G P+ + P AC P N
Sbjct: 26728 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRN 26773
Score = 30.8 bits (68), Expect = 4.9
Identities = 16/36 (44%), Positives = 19/36 (52%)
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+C ITGL GQ+Y +V A N G GP P A
Sbjct: 15253 KCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 15288
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 9/101 (8%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQ 342
S+ S+T+S+ PL +T Y V+ D + +++ + +T L G +
Sbjct: 23336 SAESITLSWNPPLYTGGCQITNYIVQ---KRDTTTTVWDVVSATVARTTLKVTKLKTGTE 23392
Query: 343 YFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKG 383
Y ++ A N G A + P A Y +EP G
Sbjct: 23393 YQFRIFAENRYGQSFALESDPIVA------QYPYKEPGPPG 23427
Score = 30.4 bits (67), Expect = 6.4
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N + T+ S+ +++Q P + + Y VE+ D ++
Sbjct: 17113 PSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 17172
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP 363
+ +TGL GQ Y +V A N G PA P
Sbjct: 17173 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 17206
Score = 30.0 bits (66), Expect = 8.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWS--MSEDFSPLAGEIIMDNLQ 328
P P ++ + S ++++EPL +V+T Y VE S +SPL+ +
Sbjct: 17310 PGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSA-----TSK 17364
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGP 357
L G QY +V+A N G GP
Sbjct: 17365 KKSHFAKHLNEGNQYLFRVAAENQYGRGP 17393
Score = 30.0 bits (66), Expect = 8.4
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQT 329
P P ++ + + S+TV + P S + + Y VE D S + + +
Sbjct: 23819 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE---KRDRSGIRWIKCNKRRITD 23875
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWG---PAQTTTPAC 365
LR +TGLT +Y +VSA N G G PA AC
Sbjct: 23876 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC 23914
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 45.1 bits (105), Expect = 3e-04
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 11/91 (12%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P P N ++ TS +S+++++ +P+ + +T Y VE ++ E+ +P AG
Sbjct: 15451 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG----- 15505
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWG 356
L+ TITGLT Q+Y +++ A N +G G
Sbjct: 15506 -LKATSYTITGLTENQEYKIRIYAMNSEGLG 15535
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 23/160 (14%)
Query: 252 EWRYRLYRRMKTGF-------------EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
E+ YR+Y G + P P+ ++ + T++T+++ +PL
Sbjct: 19747 EYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDG 19806
Query: 299 AAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-P 357
A +T Y VE+ S+D + + +L+ TI+GLT G +Y +V + N G P
Sbjct: 19807 GAPITGYTVEYKKSDDTD---WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDP 19863
Query: 358 AQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRA 397
+ ++ P A + EP SE+ + L+ + A
Sbjct: 19864 SDSSDPQIAKER------EEEPLFDIDSEMRKTLIVKAGA 19897
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 262 KTGFEHAR---APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
KT F + R +P P N+ + S+T+S++ PL A +T Y VE + +
Sbjct: 18882 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE---KRETTRK 18938
Query: 319 AGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
A I +N I L G Y+ +V A N G G PA+TT P S
Sbjct: 18939 AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS 18988
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P V L+ + + T+ +++P S + +T Y VE SE +S ++
Sbjct: 18991 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCT------QVK 19044
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TL TI+GLT G++Y +V+A N KG P Q P A
Sbjct: 19045 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIA 19083
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 281 VTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMG 340
VT +T+ TVS++ P+ + +T Y VE E S I + LRC +TGL G
Sbjct: 14278 VTKNTA-TVSWKRPVDDGGSEITGYHVE--RREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14334
Query: 341 QQYFVQVSAYNMKGWGP 357
Y +VSA N G GP
Sbjct: 14335 STYEFRVSAENRAGIGP 14351
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
PE P V + ++ T++++ PL + + Y VE + S L ++ N+QTL
Sbjct: 16335 PEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVE---RRETSRLVWTVVDANVQTL 16389
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
C +T L G +Y ++ A N G G + P A
Sbjct: 16390 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 16425
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P PTN ++ T+ S+T+++ +P+ + + Y VE +++ +P G
Sbjct: 17615 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTG----- 17669
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSN 370
L+ R I+ LT Q+Y ++V A N G G A T+ P P +
Sbjct: 17670 -LRVTRFEISKLTEHQEYKIRVCALNKVGLGEA-TSVPGTVKPED 17712
Score = 38.9 bits (89), Expect = 0.018
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEII 323
E PE P ++ + + ++T+++ P + + Y +E + +E F ++
Sbjct: 10407 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH----KVT 10462
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSNWKDYDDR 377
DNL + + T+ GL G Y +VSA N+ G G P+ T P A P+ D+ D+
Sbjct: 10463 NDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK 10522
Query: 378 EPRHKGQSEVLEG 390
G++ L G
Sbjct: 10523 LTIRVGEAFALTG 10535
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P + LM + S+++S+++P + + Y VE S+ ++ A ++
Sbjct: 15744 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA------TVK 15797
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TITGL G++Y +VSA N KG P Q + P A
Sbjct: 15798 VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIA 15836
Score = 38.9 bits (89), Expect = 0.018
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P P V L S TS ++ +++P + V Y VE +E +S I+
Sbjct: 17905 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS------IVA 17958
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+ +TGL+ GQ+Y +V AYN KG
Sbjct: 17959 ESKVCNAVVTGLSSGQEYQFRVKAYNEKG 17987
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P+ P + + + S+++S+ +P + + +Y VE SE +S A
Sbjct: 16823 AEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA------ 16876
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+++L+ IT LT G++Y +V A N KG
Sbjct: 16877 RVKSLQAVITNLTQGEEYLFRVVAVNEKG 16905
Score = 36.6 bits (83), Expect = 0.090
Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 262 KTGFEHARAPEMPTNVC-LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
K+GF + R + P V L T T S+T+ + PL + +T Y VE + S
Sbjct: 14551 KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS 14610
Query: 319 AGEIIMDNLQTLRCT--ITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
+ +CT +TGL+ G +YF +V A N G G P +TT P AS
Sbjct: 14611 TA-----TTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKAS 14657
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P ++ + T +++ + +P + +T Y VE+ ++D+ I +
Sbjct: 11105 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW------IKFKTVT 11158
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L C +TGL G+ Y +V A N+ G G TT P
Sbjct: 11159 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 11193
Score = 35.4 bits (80), Expect = 0.20
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 25/141 (17%)
Query: 246 KQLKAWEWRYRLYRRMKTGF--------EHAR-------APEMPTNVCLMVTSSTSLTVS 290
K L+ E+ +R+ + K G E AR AP+ PT + + S+TV+
Sbjct: 9975 KLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT---VSSVTRNSMTVN 10031
Query: 291 FQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC----TITGLTMGQQYFVQ 346
++EP + VT Y +E M + S + D ++ + +TGL G Y +
Sbjct: 10032 WEEPEYDGGSPVTGYWLE--MKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 10089
Query: 347 VSAYNMKGWGPAQ-TTTPACA 366
V A N G GPA + PA A
Sbjct: 10090 VYAINAAGVGPASLPSDPATA 10110
Score = 35.0 bits (79), Expect = 0.26
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMD-NLQT 329
P P NV + + ++++++ P A +T Y +E D + + + M +
Sbjct: 6886 PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIEL---RDKTSIRWDTAMTVRAED 6942
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L T+T + GQ+Y +V A N G G TP
Sbjct: 6943 LSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 6976
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
+ AP P ++ +M + +++++++ +P + +T Y +E S+ ++ +
Sbjct: 14657 SEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT------ 14710
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
++ L C + LT G++Y QV A N G + + P
Sbjct: 14711 TVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRP 14748
Score = 34.3 bits (77), Expect = 0.44
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSE--DFSPLAGEII 323
E P PT V + TS T++++ + +P+ + Y +E ++ D+ + E
Sbjct: 21944 EPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC 22003
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTT 362
+ R T+T L G++Y +VSA N G G + T
Sbjct: 22004 VKT----RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT 22038
Score = 33.9 bits (76), Expect = 0.58
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 17/136 (12%)
Query: 234 NEGFTLDNTE-------KEKQLKAWEWRYRLYRRMKTG-------FEHARAPEMPTN-VC 278
+E T++NTE K Q K +Y++ G E P+ PT +
Sbjct: 24367 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24426
Query: 279 LMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLT 338
+ S +S++ P + +T Y VE +++ + +++ + C I LT
Sbjct: 24427 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW--QLVSSAISVTTCRIVNLT 24484
Query: 339 MGQQYFVQVSAYNMKG 354
Y+ +VSA N G
Sbjct: 24485 ENAGYYFRVSAQNTFG 24500
Score = 33.5 bits (75), Expect = 0.76
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 25/131 (19%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED--FSPLAGEIIMDNLQTLRCTITGLTMG 340
++ S +++ P + +T Y +E S+ ++P+ + N T+ GL G
Sbjct: 10324 TNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-----ATVQGLIQG 10378
Query: 341 QQYFVQVSAYNMKGWGPAQTTTPA------CASPSNWKDYDDRE------------PRHK 382
+ YF +++A N G GP T+ A P +D + +E P++
Sbjct: 10379 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10438
Query: 383 GQSEVLEGLLQ 393
G SE++ +L+
Sbjct: 10439 GGSEIINYVLE 10449
Score = 33.1 bits (74), Expect = 0.99
Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNL 327
+ P +P + ++ + +++T+++++PL + +T Y +E + + +++
Sbjct: 23327 SEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM--KVVTLKP 23384
Query: 328 QTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTT 362
L T+T L G+QY ++ A N KG P +T T
Sbjct: 23385 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVT 23420
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 279 LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITG 336
L VT+ T + T+S++ PL + +T + VE+ G I+ + T R
Sbjct: 11703 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQ----KGWSIVASDVTKRLIKAN 11758
Query: 337 LTMGQQYFVQVSAYNMKGWGPA-QTTTPACA 366
L +Y+ +V A N G GP +T TP A
Sbjct: 11759 LLANNEYYFRVCAENKVGVGPTIETKTPILA 11789
Score = 32.3 bits (72), Expect = 1.7
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 270 APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQT 329
A E P NV + S S+++S+Q+P + +T Y VE D N+
Sbjct: 20462 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS--FTNVTE 20519
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKG 354
+ I+GLT QY +V A N G
Sbjct: 20520 TQFIISGLTQNSQYEFRVFARNAVG 20544
Score = 32.0 bits (71), Expect = 2.2
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 269 RAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQ 328
+ P P + ++S S+ V + EP+S + V Y +E E S L ++ +
Sbjct: 16034 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE--RKERNSILWVKLNKTPIP 16091
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG 356
+ TGL G +Y +VSA N+ G G
Sbjct: 16092 QTKFKTTGLEEGVEYEFRVSAENIVGIG 16119
Score = 32.0 bits (71), Expect = 2.2
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQTLRCTITGLTMGQ 341
+ S+TV + P++ + ++ Y +E D L +++ + ++ R +TGLT
Sbjct: 20773 TKNSMTVVWSRPIADGGSDISGYFLE---KRDKKSLGWFKVLKETIRDTRQKVTGLTENS 20829
Query: 342 QYFVQVSAYNMKGWGP 357
Y +V A N G GP
Sbjct: 20830 DYQYRVCAVNAAGQGP 20845
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDN-LQTLRC 332
P+N+ + S+T+++ P S + + +Y +E E S ++I + R
Sbjct: 21855 PSNI-----TGNSITLTWARPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRF 21907
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGPAQ--TTTPACASPSN 370
+TGLT G +Y V A N G GPA + C P N
Sbjct: 21908 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21947
Score = 31.6 bits (70), Expect = 2.9
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N+ + + +T+S+Q P + V Y VE +D ++
Sbjct: 11302 PTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVE---KQDTRKDTWGVVSSGSSKT 11356
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+ I L G +Y +V A N G GP +TP A
Sbjct: 11357 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA 11392
Score = 31.2 bits (69), Expect = 3.8
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Query: 282 TSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQTLRCTITGLTM 339
TSST++ + ++ P + Y V+ + + ++S ++I + + T+ +
Sbjct: 8708 TSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI----KVRQYTVKEIRE 8763
Query: 340 GQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRAL 398
G Y ++VSA N G GP T P + + + KG +++ G ++ A+
Sbjct: 8764 GADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAV 8822
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMS-EDFSPLAGEIIMD---N 326
P PTN ++ T+ S+T+ + +P+ A + Y VE D SP G +
Sbjct: 12192 PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQ 12251
Query: 327 LQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQ 359
L T+T L Q+Y +V A N G G PA+
Sbjct: 12252 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAE 12285
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P+ + + S+TV + EP+S + V Y +E M + S L + ++T
Sbjct: 20365 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLE--MKDRNSILWQKANKLVIRTT 20422
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSN 370
+T ++ G Y +V A N G G P+ + P AC P N
Sbjct: 20423 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRN 20468
Score = 30.8 bits (68), Expect = 4.9
Identities = 16/36 (44%), Positives = 19/36 (52%)
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+C ITGL GQ+Y +V A N G GP P A
Sbjct: 8948 KCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 8983
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 9/101 (8%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQ 342
S+ S+T+S+ PL +T Y V+ D + +++ + +T L G +
Sbjct: 17031 SAESITLSWNPPLYTGGCQITNYIVQ---KRDTTTTVWDVVSATVARTTLKVTKLKTGTE 17087
Query: 343 YFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKG 383
Y ++ A N G A + P A Y +EP G
Sbjct: 17088 YQFRIFAENRYGQSFALESDPIVA------QYPYKEPGPPG 17122
Score = 30.4 bits (67), Expect = 6.4
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N + T+ S+ +++Q P + + Y VE+ D ++
Sbjct: 10808 PSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 10867
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP 363
+ +TGL GQ Y +V A N G PA P
Sbjct: 10868 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 10901
Score = 30.0 bits (66), Expect = 8.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWS--MSEDFSPLAGEIIMDNLQ 328
P P ++ + S ++++EPL +V+T Y VE S +SPL+ +
Sbjct: 11005 PGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSA-----TSK 11059
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGP 357
L G QY +V+A N G GP
Sbjct: 11060 KKSHFAKHLNEGNQYLFRVAAENQYGRGP 11088
Score = 30.0 bits (66), Expect = 8.4
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQT 329
P P ++ + + S+TV + P S + + Y VE D S + + +
Sbjct: 17514 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE---KRDRSGIRWIKCNKRRITD 17570
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWG---PAQTTTPAC 365
LR +TGLT +Y +VSA N G G PA AC
Sbjct: 17571 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC 17609
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 45.1 bits (105), Expect = 3e-04
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 11/91 (12%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P P N ++ TS +S+++++ +P+ + +T Y VE ++ E+ +P AG
Sbjct: 15384 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG----- 15438
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWG 356
L+ TITGLT Q+Y +++ A N +G G
Sbjct: 15439 -LKATSYTITGLTENQEYKIRIYAMNSEGLG 15468
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 23/160 (14%)
Query: 252 EWRYRLYRRMKTGF-------------EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
E+ YR+Y G + P P+ ++ + T++T+++ +PL
Sbjct: 19680 EYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDG 19739
Query: 299 AAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-P 357
A +T Y VE+ S+D + + +L+ TI+GLT G +Y +V + N G P
Sbjct: 19740 GAPITGYTVEYKKSDDTD---WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDP 19796
Query: 358 AQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRA 397
+ ++ P A + EP SE+ + L+ + A
Sbjct: 19797 SDSSDPQIAKER------EEEPLFDIDSEMRKTLIVKAGA 19830
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 262 KTGFEHAR---APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
KT F + R +P P N+ + S+T+S++ PL A +T Y VE + +
Sbjct: 18815 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE---KRETTRK 18871
Query: 319 AGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
A I +N I L G Y+ +V A N G G PA+TT P S
Sbjct: 18872 AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS 18921
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P V L+ + + T+ +++P S + +T Y VE SE +S ++
Sbjct: 18924 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCT------QVK 18977
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TL TI+GLT G++Y +V+A N KG P Q P A
Sbjct: 18978 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIA 19016
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 281 VTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMG 340
VT +T+ TVS++ P+ + +T Y VE E S I + LRC +TGL G
Sbjct: 14211 VTKNTA-TVSWKRPVDDGGSEITGYHVE--RREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14267
Query: 341 QQYFVQVSAYNMKGWGP 357
Y +VSA N G GP
Sbjct: 14268 STYEFRVSAENRAGIGP 14284
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
PE P V + ++ T++++ PL + + Y VE + S L ++ N+QTL
Sbjct: 16268 PEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVE---RRETSRLVWTVVDANVQTL 16322
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
C +T L G +Y ++ A N G G + P A
Sbjct: 16323 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 16358
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P PTN ++ T+ S+T+++ +P+ + + Y VE +++ +P G
Sbjct: 17548 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTG----- 17602
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSN 370
L+ R I+ LT Q+Y ++V A N G G A T+ P P +
Sbjct: 17603 -LRVTRFEISKLTEHQEYKIRVCALNKVGLGEA-TSVPGTVKPED 17645
Score = 38.9 bits (89), Expect = 0.018
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEII 323
E PE P ++ + + ++T+++ P + + Y +E + +E F ++
Sbjct: 10340 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH----KVT 10395
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSNWKDYDDR 377
DNL + + T+ GL G Y +VSA N+ G G P+ T P A P+ D+ D+
Sbjct: 10396 NDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK 10455
Query: 378 EPRHKGQSEVLEG 390
G++ L G
Sbjct: 10456 LTIRVGEAFALTG 10468
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P + LM + S+++S+++P + + Y VE S+ ++ A ++
Sbjct: 15677 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA------TVK 15730
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TITGL G++Y +VSA N KG P Q + P A
Sbjct: 15731 VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIA 15769
Score = 38.9 bits (89), Expect = 0.018
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P P V L S TS ++ +++P + V Y VE +E +S I+
Sbjct: 17838 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS------IVA 17891
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+ +TGL+ GQ+Y +V AYN KG
Sbjct: 17892 ESKVCNAVVTGLSSGQEYQFRVKAYNEKG 17920
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P+ P + + + S+++S+ +P + + +Y VE SE +S A
Sbjct: 16756 AEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA------ 16809
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+++L+ IT LT G++Y +V A N KG
Sbjct: 16810 RVKSLQAVITNLTQGEEYLFRVVAVNEKG 16838
Score = 36.6 bits (83), Expect = 0.090
Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 262 KTGFEHARAPEMPTNVC-LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
K+GF + R + P V L T T S+T+ + PL + +T Y VE + S
Sbjct: 14484 KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS 14543
Query: 319 AGEIIMDNLQTLRCT--ITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
+ +CT +TGL+ G +YF +V A N G G P +TT P AS
Sbjct: 14544 TA-----TTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKAS 14590
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P ++ + T +++ + +P + +T Y VE+ ++D+ I +
Sbjct: 11038 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW------IKFKTVT 11091
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L C +TGL G+ Y +V A N+ G G TT P
Sbjct: 11092 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 11126
Score = 35.4 bits (80), Expect = 0.20
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 25/141 (17%)
Query: 246 KQLKAWEWRYRLYRRMKTGF--------EHAR-------APEMPTNVCLMVTSSTSLTVS 290
K L+ E+ +R+ + K G E AR AP+ PT + + S+TV+
Sbjct: 9908 KLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT---VSSVTRNSMTVN 9964
Query: 291 FQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC----TITGLTMGQQYFVQ 346
++EP + VT Y +E M + S + D ++ + +TGL G Y +
Sbjct: 9965 WEEPEYDGGSPVTGYWLE--MKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 10022
Query: 347 VSAYNMKGWGPAQ-TTTPACA 366
V A N G GPA + PA A
Sbjct: 10023 VYAINAAGVGPASLPSDPATA 10043
Score = 35.0 bits (79), Expect = 0.26
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMD-NLQT 329
P P NV + + ++++++ P A +T Y +E D + + + M +
Sbjct: 6819 PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIEL---RDKTSIRWDTAMTVRAED 6875
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L T+T + GQ+Y +V A N G G TP
Sbjct: 6876 LSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 6909
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
+ AP P ++ +M + +++++++ +P + +T Y +E S+ ++ +
Sbjct: 14590 SEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT------ 14643
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
++ L C + LT G++Y QV A N G + + P
Sbjct: 14644 TVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRP 14681
Score = 34.3 bits (77), Expect = 0.44
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSE--DFSPLAGEII 323
E P PT V + TS T++++ + +P+ + Y +E ++ D+ + E
Sbjct: 21877 EPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC 21936
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTT 362
+ R T+T L G++Y +VSA N G G + T
Sbjct: 21937 VKT----RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT 21971
Score = 33.9 bits (76), Expect = 0.58
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 17/136 (12%)
Query: 234 NEGFTLDNTE-------KEKQLKAWEWRYRLYRRMKTG-------FEHARAPEMPTN-VC 278
+E T++NTE K Q K +Y++ G E P+ PT +
Sbjct: 24300 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24359
Query: 279 LMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLT 338
+ S +S++ P + +T Y VE +++ + +++ + C I LT
Sbjct: 24360 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW--QLVSSAISVTTCRIVNLT 24417
Query: 339 MGQQYFVQVSAYNMKG 354
Y+ +VSA N G
Sbjct: 24418 ENAGYYFRVSAQNTFG 24433
Score = 33.5 bits (75), Expect = 0.76
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 25/131 (19%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED--FSPLAGEIIMDNLQTLRCTITGLTMG 340
++ S +++ P + +T Y +E S+ ++P+ + N T+ GL G
Sbjct: 10257 TNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-----ATVQGLIQG 10311
Query: 341 QQYFVQVSAYNMKGWGPAQTTTPA------CASPSNWKDYDDRE------------PRHK 382
+ YF +++A N G GP T+ A P +D + +E P++
Sbjct: 10312 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10371
Query: 383 GQSEVLEGLLQ 393
G SE++ +L+
Sbjct: 10372 GGSEIINYVLE 10382
Score = 33.1 bits (74), Expect = 0.99
Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNL 327
+ P +P + ++ + +++T+++++PL + +T Y +E + + +++
Sbjct: 23260 SEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM--KVVTLKP 23317
Query: 328 QTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTT 362
L T+T L G+QY ++ A N KG P +T T
Sbjct: 23318 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVT 23353
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 279 LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITG 336
L VT+ T + T+S++ PL + +T + VE+ G I+ + T R
Sbjct: 11636 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQ----KGWSIVASDVTKRLIKAN 11691
Query: 337 LTMGQQYFVQVSAYNMKGWGPA-QTTTPACA 366
L +Y+ +V A N G GP +T TP A
Sbjct: 11692 LLANNEYYFRVCAENKVGVGPTIETKTPILA 11722
Score = 32.3 bits (72), Expect = 1.7
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 270 APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQT 329
A E P NV + S S+++S+Q+P + +T Y VE D N+
Sbjct: 20395 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS--FTNVTE 20452
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKG 354
+ I+GLT QY +V A N G
Sbjct: 20453 TQFIISGLTQNSQYEFRVFARNAVG 20477
Score = 32.0 bits (71), Expect = 2.2
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 269 RAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQ 328
+ P P + ++S S+ V + EP+S + V Y +E E S L ++ +
Sbjct: 15967 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE--RKERNSILWVKLNKTPIP 16024
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG 356
+ TGL G +Y +VSA N+ G G
Sbjct: 16025 QTKFKTTGLEEGVEYEFRVSAENIVGIG 16052
Score = 32.0 bits (71), Expect = 2.2
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQTLRCTITGLTMGQ 341
+ S+TV + P++ + ++ Y +E D L +++ + ++ R +TGLT
Sbjct: 20706 TKNSMTVVWSRPIADGGSDISGYFLE---KRDKKSLGWFKVLKETIRDTRQKVTGLTENS 20762
Query: 342 QYFVQVSAYNMKGWGP 357
Y +V A N G GP
Sbjct: 20763 DYQYRVCAVNAAGQGP 20778
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDN-LQTLRC 332
P+N+ + S+T+++ P S + + +Y +E E S ++I + R
Sbjct: 21788 PSNI-----TGNSITLTWARPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRF 21840
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGPAQ--TTTPACASPSN 370
+TGLT G +Y V A N G GPA + C P N
Sbjct: 21841 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21880
Score = 31.6 bits (70), Expect = 2.9
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N+ + + +T+S+Q P + V Y VE +D ++
Sbjct: 11235 PTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVE---KQDTRKDTWGVVSSGSSKT 11289
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+ I L G +Y +V A N G GP +TP A
Sbjct: 11290 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA 11325
Score = 31.2 bits (69), Expect = 3.8
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Query: 282 TSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQTLRCTITGLTM 339
TSST++ + ++ P + Y V+ + + ++S ++I + + T+ +
Sbjct: 8641 TSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI----KVRQYTVKEIRE 8696
Query: 340 GQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRAL 398
G Y ++VSA N G GP T P + + + KG +++ G ++ A+
Sbjct: 8697 GADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAV 8755
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMS-EDFSPLAGEIIMD---N 326
P PTN ++ T+ S+T+ + +P+ A + Y VE D SP G +
Sbjct: 12125 PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQ 12184
Query: 327 LQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQ 359
L T+T L Q+Y +V A N G G PA+
Sbjct: 12185 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAE 12218
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P+ + + S+TV + EP+S + V Y +E M + S L + ++T
Sbjct: 20298 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLE--MKDRNSILWQKANKLVIRTT 20355
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSN 370
+T ++ G Y +V A N G G P+ + P AC P N
Sbjct: 20356 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRN 20401
Score = 30.8 bits (68), Expect = 4.9
Identities = 16/36 (44%), Positives = 19/36 (52%)
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+C ITGL GQ+Y +V A N G GP P A
Sbjct: 8881 KCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 8916
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 9/101 (8%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQ 342
S+ S+T+S+ PL +T Y V+ D + +++ + +T L G +
Sbjct: 16964 SAESITLSWNPPLYTGGCQITNYIVQ---KRDTTTTVWDVVSATVARTTLKVTKLKTGTE 17020
Query: 343 YFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKG 383
Y ++ A N G A + P A Y +EP G
Sbjct: 17021 YQFRIFAENRYGQSFALESDPIVA------QYPYKEPGPPG 17055
Score = 30.4 bits (67), Expect = 6.4
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N + T+ S+ +++Q P + + Y VE+ D ++
Sbjct: 10741 PSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 10800
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP 363
+ +TGL GQ Y +V A N G PA P
Sbjct: 10801 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 10834
Score = 30.0 bits (66), Expect = 8.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWS--MSEDFSPLAGEIIMDNLQ 328
P P ++ + S ++++EPL +V+T Y VE S +SPL+ +
Sbjct: 10938 PGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSA-----TSK 10992
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGP 357
L G QY +V+A N G GP
Sbjct: 10993 KKSHFAKHLNEGNQYLFRVAAENQYGRGP 11021
Score = 30.0 bits (66), Expect = 8.4
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQT 329
P P ++ + + S+TV + P S + + Y VE D S + + +
Sbjct: 17447 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE---KRDRSGIRWIKCNKRRITD 17503
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWG---PAQTTTPAC 365
LR +TGLT +Y +VSA N G G PA AC
Sbjct: 17504 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC 17542
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 45.1 bits (105), Expect = 3e-04
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 11/91 (12%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P P N ++ TS +S+++++ +P+ + +T Y VE ++ E+ +P AG
Sbjct: 15259 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG----- 15313
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWG 356
L+ TITGLT Q+Y +++ A N +G G
Sbjct: 15314 -LKATSYTITGLTENQEYKIRIYAMNSEGLG 15343
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 23/160 (14%)
Query: 252 EWRYRLYRRMKTGF-------------EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVN 298
E+ YR+Y G + P P+ ++ + T++T+++ +PL
Sbjct: 19555 EYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDG 19614
Query: 299 AAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-P 357
A +T Y VE+ S+D + + +L+ TI+GLT G +Y +V + N G P
Sbjct: 19615 GAPITGYTVEYKKSDDTD---WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDP 19671
Query: 358 AQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRA 397
+ ++ P A + EP SE+ + L+ + A
Sbjct: 19672 SDSSDPQIAKER------EEEPLFDIDSEMRKTLIVKAGA 19705
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 262 KTGFEHAR---APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
KT F + R +P P N+ + S+T+S++ PL A +T Y VE + +
Sbjct: 18690 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE---KRETTRK 18746
Query: 319 AGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
A I +N I L G Y+ +V A N G G PA+TT P S
Sbjct: 18747 AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS 18796
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P V L+ + + T+ +++P S + +T Y VE SE +S ++
Sbjct: 18799 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCT------QVK 18852
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TL TI+GLT G++Y +V+A N KG P Q P A
Sbjct: 18853 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIA 18891
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 281 VTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMG 340
VT +T+ TVS++ P+ + +T Y VE E S I + LRC +TGL G
Sbjct: 14086 VTKNTA-TVSWKRPVDDGGSEITGYHVE--RREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14142
Query: 341 QQYFVQVSAYNMKGWGP 357
Y +VSA N G GP
Sbjct: 14143 STYEFRVSAENRAGIGP 14159
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
PE P V + ++ T++++ PL + + Y VE + S L ++ N+QTL
Sbjct: 16143 PEGP--VVISGVTAEKCTLAWKPPLQDGGSDIINYIVE---RRETSRLVWTVVDANVQTL 16197
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
C +T L G +Y ++ A N G G + P A
Sbjct: 16198 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 16233
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED-----FSPLAGEIIMD 325
P PTN ++ T+ S+T+++ +P+ + + Y VE +++ +P G
Sbjct: 17423 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTG----- 17477
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSN 370
L+ R I+ LT Q+Y ++V A N G G A T+ P P +
Sbjct: 17478 -LRVTRFEISKLTEHQEYKIRVCALNKVGLGEA-TSVPGTVKPED 17520
Score = 38.9 bits (89), Expect = 0.018
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEII 323
E PE P ++ + + ++T+++ P + + Y +E + +E F ++
Sbjct: 10215 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH----KVT 10270
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSNWKDYDDR 377
DNL + + T+ GL G Y +VSA N+ G G P+ T P A P+ D+ D+
Sbjct: 10271 NDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK 10330
Query: 378 EPRHKGQSEVLEG 390
G++ L G
Sbjct: 10331 LTIRVGEAFALTG 10343
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P + LM + S+++S+++P + + Y VE S+ ++ A ++
Sbjct: 15552 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA------TVK 15605
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACA 366
TITGL G++Y +VSA N KG P Q + P A
Sbjct: 15606 VTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIA 15644
Score = 38.9 bits (89), Expect = 0.018
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P P V L S TS ++ +++P + V Y VE +E +S I+
Sbjct: 17713 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS------IVA 17766
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+ +TGL+ GQ+Y +V AYN KG
Sbjct: 17767 ESKVCNAVVTGLSSGQEYQFRVKAYNEKG 17795
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
A P+ P + + + S+++S+ +P + + +Y VE SE +S A
Sbjct: 16631 AEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA------ 16684
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKG 354
+++L+ IT LT G++Y +V A N KG
Sbjct: 16685 RVKSLQAVITNLTQGEEYLFRVVAVNEKG 16713
Score = 36.6 bits (83), Expect = 0.090
Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 262 KTGFEHARAPEMPTNVC-LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPL 318
K+GF + R + P V L T T S+T+ + PL + +T Y VE + S
Sbjct: 14359 KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYS 14418
Query: 319 AGEIIMDNLQTLRCT--ITGLTMGQQYFVQVSAYNMKGWG-PAQTTTPACAS 367
+ +CT +TGL+ G +YF +V A N G G P +TT P AS
Sbjct: 14419 TA-----TTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKAS 14465
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P ++ + T +++ + +P + +T Y VE+ ++D+ I +
Sbjct: 10913 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW------IKFKTVT 10966
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L C +TGL G+ Y +V A N+ G G TT P
Sbjct: 10967 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 11001
Score = 35.4 bits (80), Expect = 0.20
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 25/141 (17%)
Query: 246 KQLKAWEWRYRLYRRMKTGF--------EHAR-------APEMPTNVCLMVTSSTSLTVS 290
K L+ E+ +R+ + K G E AR AP+ PT + + S+TV+
Sbjct: 9783 KLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT---VSSVTRNSMTVN 9839
Query: 291 FQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC----TITGLTMGQQYFVQ 346
++EP + VT Y +E M + S + D ++ + +TGL G Y +
Sbjct: 9840 WEEPEYDGGSPVTGYWLE--MKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFR 9897
Query: 347 VSAYNMKGWGPAQ-TTTPACA 366
V A N G GPA + PA A
Sbjct: 9898 VYAINAAGVGPASLPSDPATA 9918
Score = 35.0 bits (79), Expect = 0.26
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMD-NLQT 329
P P NV + + ++++++ P A +T Y +E D + + + M +
Sbjct: 6694 PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIEL---RDKTSIRWDTAMTVRAED 6750
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
L T+T + GQ+Y +V A N G G TP
Sbjct: 6751 LSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATP 6784
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMD 325
+ AP P ++ +M + +++++++ +P + +T Y +E S+ ++ +
Sbjct: 14465 SEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT------ 14518
Query: 326 NLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTP 363
++ L C + LT G++Y QV A N G + + P
Sbjct: 14519 TVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRP 14556
Score = 34.3 bits (77), Expect = 0.44
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
Query: 266 EHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSE--DFSPLAGEII 323
E P PT V + TS T++++ + +P+ + Y +E ++ D+ + E
Sbjct: 21752 EPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC 21811
Query: 324 MDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTT 362
+ R T+T L G++Y +VSA N G G + T
Sbjct: 21812 VKT----RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT 21846
Score = 33.9 bits (76), Expect = 0.58
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 17/136 (12%)
Query: 234 NEGFTLDNTE-------KEKQLKAWEWRYRLYRRMKTG-------FEHARAPEMPTN-VC 278
+E T++NTE K Q K +Y++ G E P+ PT +
Sbjct: 24175 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24234
Query: 279 LMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLT 338
+ S +S++ P + +T Y VE +++ + +++ + C I LT
Sbjct: 24235 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW--QLVSSAISVTTCRIVNLT 24292
Query: 339 MGQQYFVQVSAYNMKG 354
Y+ +VSA N G
Sbjct: 24293 ENAGYYFRVSAQNTFG 24308
Score = 33.5 bits (75), Expect = 0.76
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 25/131 (19%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSED--FSPLAGEIIMDNLQTLRCTITGLTMG 340
++ S +++ P + +T Y +E S+ ++P+ + N T+ GL G
Sbjct: 10132 TNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-----ATVQGLIQG 10186
Query: 341 QQYFVQVSAYNMKGWGPAQTTTPA------CASPSNWKDYDDRE------------PRHK 382
+ YF +++A N G GP T+ A P +D + +E P++
Sbjct: 10187 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10246
Query: 383 GQSEVLEGLLQ 393
G SE++ +L+
Sbjct: 10247 GGSEIINYVLE 10257
Score = 33.1 bits (74), Expect = 0.99
Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 268 ARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNL 327
+ P +P + ++ + +++T+++++PL + +T Y +E + + +++
Sbjct: 23135 SEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM--KVVTLKP 23192
Query: 328 QTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTT 362
L T+T L G+QY ++ A N KG P +T T
Sbjct: 23193 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVT 23228
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 279 LMVTSST--SLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITG 336
L VT+ T + T+S++ PL + +T + VE+ G I+ + T R
Sbjct: 11511 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQ----KGWSIVASDVTKRLIKAN 11566
Query: 337 LTMGQQYFVQVSAYNMKGWGPA-QTTTPACA 366
L +Y+ +V A N G GP +T TP A
Sbjct: 11567 LLANNEYYFRVCAENKVGVGPTIETKTPILA 11597
Score = 32.3 bits (72), Expect = 1.7
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 270 APEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQT 329
A E P NV + S S+++S+Q+P + +T Y VE D N+
Sbjct: 20270 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKAS--FTNVTE 20327
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKG 354
+ I+GLT QY +V A N G
Sbjct: 20328 TQFIISGLTQNSQYEFRVFARNAVG 20352
Score = 32.0 bits (71), Expect = 2.2
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 269 RAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQ 328
+ P P + ++S S+ V + EP+S + V Y +E E S L ++ +
Sbjct: 15842 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE--RKERNSILWVKLNKTPIP 15899
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWG 356
+ TGL G +Y +VSA N+ G G
Sbjct: 15900 QTKFKTTGLEEGVEYEFRVSAENIVGIG 15927
Score = 32.0 bits (71), Expect = 2.2
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQTLRCTITGLTMGQ 341
+ S+TV + P++ + ++ Y +E D L +++ + ++ R +TGLT
Sbjct: 20581 TKNSMTVVWSRPIADGGSDISGYFLE---KRDKKSLGWFKVLKETIRDTRQKVTGLTENS 20637
Query: 342 QYFVQVSAYNMKGWGP 357
Y +V A N G GP
Sbjct: 20638 DYQYRVCAVNAAGQGP 20653
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDN-LQTLRC 332
P+N+ + S+T+++ P S + + +Y +E E S ++I + R
Sbjct: 21663 PSNI-----TGNSITLTWARPESDGGSEIQQYILE--RREKKSTRWVKVISKRPISETRF 21715
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGPAQ--TTTPACASPSN 370
+TGLT G +Y V A N G GPA + C P N
Sbjct: 21716 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21755
Score = 31.6 bits (70), Expect = 2.9
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N+ + + +T+S+Q P + V Y VE +D ++
Sbjct: 11110 PTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVE---KQDTRKDTWGVVSSGSSKT 11164
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+ I L G +Y +V A N G GP +TP A
Sbjct: 11165 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA 11200
Score = 31.2 bits (69), Expect = 3.8
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Query: 282 TSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQTLRCTITGLTM 339
TSST++ + ++ P + Y V+ + + ++S ++I + + T+ +
Sbjct: 8516 TSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI----KVRQYTVKEIRE 8571
Query: 340 GQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRAL 398
G Y ++VSA N G GP T P + + + KG +++ G ++ A+
Sbjct: 8572 GADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAV 8630
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMS-EDFSPLAGEIIMD---N 326
P PTN ++ T+ S+T+ + +P+ A + Y VE D SP G +
Sbjct: 12000 PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQ 12059
Query: 327 LQTLRCTITGLTMGQQYFVQVSAYNMKGWG-PAQ 359
L T+T L Q+Y +V A N G G PA+
Sbjct: 12060 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAE 12093
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P+ + + S+TV + EP+S + V Y +E M + S L + ++T
Sbjct: 20173 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLE--MKDRNSILWQKANKLVIRTT 20230
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP-----ACASPSN 370
+T ++ G Y +V A N G G P+ + P AC P N
Sbjct: 20231 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRN 20276
Score = 30.8 bits (68), Expect = 4.9
Identities = 16/36 (44%), Positives = 19/36 (52%)
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACA 366
+C ITGL GQ+Y +V A N G GP P A
Sbjct: 8756 KCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 8791
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 9/101 (8%)
Query: 283 SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQ 342
S+ S+T+S+ PL +T Y V+ D + +++ + +T L G +
Sbjct: 16839 SAESITLSWNPPLYTGGCQITNYIVQ---KRDTTTTVWDVVSATVARTTLKVTKLKTGTE 16895
Query: 343 YFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKG 383
Y ++ A N G A + P A Y +EP G
Sbjct: 16896 YQFRIFAENRYGQSFALESDPIVA------QYPYKEPGPPG 16930
Score = 30.4 bits (67), Expect = 6.4
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P P N + T+ S+ +++Q P + + Y VE+ D ++
Sbjct: 10616 PSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 10675
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG-PAQTTTP 363
+ +TGL GQ Y +V A N G PA P
Sbjct: 10676 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 10709
Score = 30.0 bits (66), Expect = 8.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWS--MSEDFSPLAGEIIMDNLQ 328
P P ++ + S ++++EPL +V+T Y VE S +SPL+ +
Sbjct: 10813 PGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSA-----TSK 10867
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGP 357
L G QY +V+A N G GP
Sbjct: 10868 KKSHFAKHLNEGNQYLFRVAAENQYGRGP 10896
Score = 30.0 bits (66), Expect = 8.4
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAG-EIIMDNLQT 329
P P ++ + + S+TV + P S + + Y VE D S + + +
Sbjct: 17322 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE---KRDRSGIRWIKCNKRRITD 17378
Query: 330 LRCTITGLTMGQQYFVQVSAYNMKGWG---PAQTTTPAC 365
LR +TGLT +Y +VSA N G G PA AC
Sbjct: 17379 LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC 17417
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 15/99 (15%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLS-VNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC 332
P NV L V +S S+ VS+ P S +T YK+ + GE+ L
Sbjct: 626 PQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTR----RGEMETLEPNNLWY 681
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSNW 371
TGL G QY QVSA + G GP PSNW
Sbjct: 682 LFTGLEKGSQYSFQVSAMTVNGTGP----------PSNW 710
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 21/138 (15%)
Query: 238 TLDNTEKEKQLKAWE------WRYRLYRRMKTGFEHARAPEM----------PTNVCLMV 281
TL+ +EKE A + + +RL R K GF E+ P N+
Sbjct: 870 TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEG 929
Query: 282 TSSTSLTVSFQEP-LSVNAAVVTRYKVEW-SMSEDFSPLAGEIIMDNLQTLRCTITGLTM 339
T+STS+ +S+Q P L+ ++T+Y + + ++ P+ ++I+ T+ T+TGL
Sbjct: 930 TTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPME-QLIVPADTTM--TLTGLKP 986
Query: 340 GQQYFVQVSAYNMKGWGP 357
Y V+V A+ KG GP
Sbjct: 987 DTTYDVKVRAHTSKGPGP 1004
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 274 PTNVCLMVTSSTSLTVSFQEP-LSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC 332
P ++ SSTS+ VS+Q P + ++T Y ++++ + EI+ T +
Sbjct: 613 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKY 672
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGP 357
+ L +Y + V+A+ G GP
Sbjct: 673 LLEQLEKWTEYRITVTAHTDVGPGP 697
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 21/138 (15%)
Query: 238 TLDNTEKEKQLKAWE------WRYRLYRRMKTGFEHARAPEM----------PTNVCLMV 281
TL+ +EKE A + + +RL R K GF E+ P N+
Sbjct: 857 TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEG 916
Query: 282 TSSTSLTVSFQEP-LSVNAAVVTRYKVEW-SMSEDFSPLAGEIIMDNLQTLRCTITGLTM 339
T+STS+ +S+Q P L+ ++T+Y + + ++ P+ ++I+ T+ T+TGL
Sbjct: 917 TTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPME-QLIVPADTTM--TLTGLKP 973
Query: 340 GQQYFVQVSAYNMKGWGP 357
Y V+V A+ KG GP
Sbjct: 974 DTTYDVKVRAHTSKGPGP 991
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 274 PTNVCLMVTSSTSLTVSFQEP-LSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC 332
P ++ SSTS+ VS+Q P + ++T Y ++++ + EI+ T +
Sbjct: 600 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKY 659
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGP 357
+ L +Y + V+A+ G GP
Sbjct: 660 LLEQLEKWTEYRITVTAHTDVGPGP 684
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 21/138 (15%)
Query: 238 TLDNTEKEKQLKAWE------WRYRLYRRMKTGFEHARAPEM----------PTNVCLMV 281
TL+ +EKE A + + +RL R K GF E+ P N+
Sbjct: 861 TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEG 920
Query: 282 TSSTSLTVSFQEP-LSVNAAVVTRYKVEW-SMSEDFSPLAGEIIMDNLQTLRCTITGLTM 339
T+STS+ +S+Q P L+ ++T+Y + + ++ P+ ++I+ T+ T+TGL
Sbjct: 921 TTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPME-QLIVPADTTM--TLTGLKP 977
Query: 340 GQQYFVQVSAYNMKGWGP 357
Y V+V A+ KG GP
Sbjct: 978 DTTYDVKVRAHTSKGPGP 995
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 274 PTNVCLMVTSSTSLTVSFQEP-LSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRC 332
P ++ SSTS+ VS+Q P + ++T Y ++++ + EI+ T +
Sbjct: 613 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKY 672
Query: 333 TITGLTMGQQYFVQVSAYNMKGWGP 357
+ L +Y + V+A+ G GP
Sbjct: 673 LLEQLEKWTEYRITVTAHTDVGPGP 697
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 38.9 bits (89), Expect = 0.018
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P ++ S+T + V + PL N + Y+V++ ED A +I QT
Sbjct: 477 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQT-STK 535
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGPAQTTT-------PACASPSN--WKDYDDR 377
IT L Y + V AYN G GP+ T P P N W D +
Sbjct: 536 ITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSK 588
>gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
Length = 282
Score = 38.9 bits (89), Expect = 0.018
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P ++ S+T + V + PL N + Y+V++ ED A +I QT
Sbjct: 61 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQT-STK 119
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGPAQTTT-------PACASPSN--WKDYDDR 377
IT L Y + V AYN G GP+ T P P N W D +
Sbjct: 120 ITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSK 172
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 38.9 bits (89), Expect = 0.018
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P ++ S+T + V + PL N + Y+V++ ED A +I QT
Sbjct: 805 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQT-STK 863
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGPAQTTT-------PACASPSN--WKDYDDR 377
IT L Y + V AYN G GP+ T P P N W D +
Sbjct: 864 ITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSK 916
>gi|71274109 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, epsilon [Homo sapiens]
Length = 500
Score = 38.5 bits (88), Expect = 0.024
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 137 GNEAMFEAVEQQDMDAVQILLY------QYTPEELDLNTPNSEGLTPLDIAIMTNNVPIA 190
G+ A+ A ++Q + + LL + T LDL N +GL L IA + N P+
Sbjct: 327 GDTALHVACQRQHLACARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQKNQPLM 386
Query: 191 RILLRTGARESPHFVSLESRAMHLNTLVQE 220
+LLR GA + A+HL QE
Sbjct: 387 ELLLRNGADIDVQEGTSGKTALHLAVETQE 416
>gi|21389501 coiled-coil domain containing 52 [Homo sapiens]
Length = 855
Score = 38.5 bits (88), Expect = 0.024
Identities = 44/196 (22%), Positives = 76/196 (38%), Gaps = 21/196 (10%)
Query: 87 HSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVE 146
H N + + NLS+ L SHS+ ++ T ++ L + + NE++ +
Sbjct: 608 HMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQ--R 665
Query: 147 QQDMDAVQILLYQYTPEELDLNT------PNSEGLTPLD----IAIMTNNVPIARILLRT 196
+ M + L Q + + +N +GL L+ + MT+ P+A+ L
Sbjct: 666 KDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQSLTPG 725
Query: 197 GARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYR 256
S+E R LN EA+ ++ +L Q + G L QL W
Sbjct: 726 ---------SMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEG 776
Query: 257 LYRRMKTGFEHARAPE 272
R ++ A APE
Sbjct: 777 AKRTIEVSIPGAEAPE 792
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 38.5 bits (88), Expect = 0.024
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSM--SEDFSPLAGEIIMDNLQ 328
P P + L SS+S+TVS++ P + + Y +E + ++ P++ +M Q
Sbjct: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
Query: 329 TLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEV 387
T+R L +G ++ ++VSA + G GP N + R PRH Q+ +
Sbjct: 131 TVR----NLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYI 185
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P+ P + ++TS+T+++ S N V+ Y +E+ P I +++ T
Sbjct: 323 PKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQ---IKEDITTT 376
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R +I GL+ +Y + VSA N G GP
Sbjct: 377 RYSIGGLSPNSEYEIWVSAVNSIGQGP 403
Score = 33.1 bits (74), Expect = 0.99
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P NV + S+T++ V ++EP+ N ++ Y+V ++M E P+ + +L T
Sbjct: 421 PRNVQARMLSATTMIVQWEEPVEPN-GLIRGYRVYYTM-EPEHPVGNWQKHNVDDSLLTT 478
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGP 357
+ L + Y V+V A+ G GP
Sbjct: 479 VGSLLEDETYTVRVLAFTSVGDGP 502
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P+ P + ++TS+T+++ S N V+ Y +E+ P I +++ T
Sbjct: 319 PKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQ---IKEDITTT 372
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R +I GL+ +Y + VSA N G GP
Sbjct: 373 RYSIGGLSPNSEYEIWVSAVNSIGQGP 399
Score = 33.1 bits (74), Expect = 0.99
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P NV + S+T++ V ++EP+ N ++ Y+V ++M E P+ + +L T
Sbjct: 417 PRNVQARMLSATTMIVQWEEPVEPN-GLIRGYRVYYTM-EPEHPVGNWQKHNVDDSLLTT 474
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGP 357
+ L + Y V+V A+ G GP
Sbjct: 475 VGSLLEDETYTVRVLAFTSVGDGP 498
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P+ P + ++TS+T+++ S N V+ Y +E+ P I +++ T
Sbjct: 319 PKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQ---IKEDITTT 372
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R +I GL+ +Y + VSA N G GP
Sbjct: 373 RYSIGGLSPNSEYEIWVSAVNSIGQGP 399
Score = 33.1 bits (74), Expect = 0.99
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P NV + S+T++ V ++EP+ N ++ Y+V ++M E P+ + +L T
Sbjct: 417 PRNVQARMLSATTMIVQWEEPVEPN-GLIRGYRVYYTM-EPEHPVGNWQKHNVDDSLLTT 474
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGP 357
+ L + Y V+V A+ G GP
Sbjct: 475 VGSLLEDETYTVRVLAFTSVGDGP 498
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 37.7 bits (86), Expect = 0.040
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P+ P + ++TS+T+++ S N V+ Y +E+ P I +++ T
Sbjct: 332 PKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQ---IKEDITTT 385
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP 357
R +I GL+ +Y + VSA N G GP
Sbjct: 386 RYSIGGLSPNSEYEIWVSAVNSIGQGP 412
Score = 33.1 bits (74), Expect = 0.99
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCT 333
P NV + S+T++ V ++EP+ N ++ Y+V ++M E P+ + +L T
Sbjct: 430 PRNVQARMLSATTMIVQWEEPVEPN-GLIRGYRVYYTM-EPEHPVGNWQKHNVDDSLLTT 487
Query: 334 ITGLTMGQQYFVQVSAYNMKGWGP 357
+ L + Y V+V A+ G GP
Sbjct: 488 VGSLLEDETYTVRVLAFTSVGDGP 511
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 37.4 bits (85), Expect = 0.052
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 272 EMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLR 331
E PT V + V SS+ ++V ++ L +V Y++ + + D A + + + Q
Sbjct: 810 EAPTEVGVKVLSSSEISVHWEHVLE---KIVESYQIRYWAAHDKEEAANRVQVTS-QEYS 865
Query: 332 CTITGLTMGQQYFVQVSAYNMKGWGP 357
+ L QYF++V A N G GP
Sbjct: 866 ARLENLLPDTQYFIEVGACNSAGCGP 891
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 37.4 bits (85), Expect = 0.052
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 272 EMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLR 331
E PT V + V SS+ ++V ++ L +V Y++ + + D A + + + Q
Sbjct: 799 EAPTEVGVKVLSSSEISVHWEHVLE---KIVESYQIRYWAAHDKEEAANRVQVTS-QEYS 854
Query: 332 CTITGLTMGQQYFVQVSAYNMKGWGP 357
+ L QYF++V A N G GP
Sbjct: 855 ARLENLLPDTQYFIEVGACNSAGCGP 880
>gi|118150656 ankyrin repeat domain 7 [Homo sapiens]
Length = 254
Score = 37.0 bits (84), Expect = 0.069
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 138 NEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTG 197
N + AV Q + V+ LL +Y E DL N +G TPL +A++ NN + + LL G
Sbjct: 126 NTVLHYAVCGQSLSLVEKLL-EY---EADLEAKNKDGYTPLLVAVINNNPKMVKFLLEKG 181
Query: 198 A 198
A
Sbjct: 182 A 182
Score = 32.0 bits (71), Expect = 2.2
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 102 NLSEK-LKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNE---AMFEAVEQQDMDAVQILL 157
NL EK LK H + + + L ++K VN Q + + A D V L+
Sbjct: 20 NLREKDLKKLHRAASVGDLKKLKEYLQIKKYDVNMQDKKYRTPLHLACANGHTDVVLFLI 79
Query: 158 YQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGA 198
Q + +N +SE +PL A+ N A ILL GA
Sbjct: 80 EQ----QCKINVRDSENKSPLIKAVQCQNEDCATILLNFGA 116
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 37.0 bits (84), Expect = 0.069
Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 12/104 (11%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P+ P ++ + T++TS+T+++ S N+ VT Y +++ + P +D + T
Sbjct: 319 PKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQE---VDGVATT 372
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP------AQTTTPACASP 368
R +I GL+ +Y +V A N G GP A+T A +SP
Sbjct: 373 RYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP 416
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 37.0 bits (84), Expect = 0.069
Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 12/104 (11%)
Query: 271 PEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTL 330
P+ P ++ + T++TS+T+++ S N+ VT Y +++ + P +D + T
Sbjct: 319 PKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQE---VDGVATT 372
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWGP------AQTTTPACASP 368
R +I GL+ +Y +V A N G GP A+T A +SP
Sbjct: 373 RYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP 416
Score = 32.3 bits (72), Expect = 1.7
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 274 PTNVCLMVTSSTSLTVSFQEPL-SVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNL--QTL 330
P V + +ST++ V ++ P+ S + Y+V + E+ P II D + +
Sbjct: 712 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 771
Query: 331 RCTITGLTMGQQYFVQVSAYNMKGWG 356
TI+GLT Y V V+AY KG G
Sbjct: 772 ETTISGLTPETTYSVTVAAYTTKGDG 797
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 36.6 bits (83), Expect = 0.090
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 129 RKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVP 188
+KT V F A D D V LL++ D+N N +GLT L A + +NV
Sbjct: 32 QKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGA----DINYANVDGLTALHQACIDDNVD 87
Query: 189 IARILLRTGA 198
+ + L+ GA
Sbjct: 88 MVKFLVENGA 97
Score = 35.4 bits (80), Expect = 0.20
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 11/115 (9%)
Query: 134 NFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARIL 193
N G A+ +A ++D V+ L+ ++N P++EG PL A + IA L
Sbjct: 70 NVDGLTALHQACIDDNVDMVKFLV----ENGANINQPDNEGWIPLHAAASCGYLDIAEFL 125
Query: 194 LRTGARESPHFVSLESRA-MHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQ 247
+ GA H ++ S L+ +EA E + L +V +G ++ KE++
Sbjct: 126 IGQGA----HVGAVNSEGDTPLDIAEEEAMEEL--LQNEVNRQGVDIEAARKEEE 174
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 36.6 bits (83), Expect = 0.090
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 129 RKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVP 188
+KT V F A D D V LL++ D+N N +GLT L A + +NV
Sbjct: 32 QKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGA----DINYANVDGLTALHQACIDDNVD 87
Query: 189 IARILLRTGA 198
+ + L+ GA
Sbjct: 88 MVKFLVENGA 97
Score = 35.4 bits (80), Expect = 0.20
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 11/115 (9%)
Query: 134 NFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARIL 193
N G A+ +A ++D V+ L+ ++N P++EG PL A + IA L
Sbjct: 70 NVDGLTALHQACIDDNVDMVKFLV----ENGANINQPDNEGWIPLHAAASCGYLDIAEFL 125
Query: 194 LRTGARESPHFVSLESRA-MHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQ 247
+ GA H ++ S L+ +EA E + L +V +G ++ KE++
Sbjct: 126 IGQGA----HVGAVNSEGDTPLDIAEEEAMEEL--LQNEVNRQGVDIEAARKEEE 174
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 36.6 bits (83), Expect = 0.090
Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 10/133 (7%)
Query: 241 NTEKEKQLKAWEWRYRLYRRMKTGFEHARA--------PEM-PTNVCLMVTSSTSLTVSF 291
+ E + +E + R Y R G E A P + PT V SS+ + V++
Sbjct: 774 SNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTW 833
Query: 292 QEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYN 351
+ ++ Y++ + + D A + L T ++GL +Y V V AYN
Sbjct: 834 EPVQQDMNGILLGYEIRYWKAGDKEAAADRVRTAGLDT-SARVSGLHPNTKYHVTVRAYN 892
Query: 352 MKGWGPAQTTTPA 364
G GPA + A
Sbjct: 893 RAGTGPASPSANA 905
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.131 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,713,982
Number of Sequences: 37866
Number of extensions: 1179011
Number of successful extensions: 4414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 3868
Number of HSP's gapped (non-prelim): 606
length of query: 763
length of database: 18,247,518
effective HSP length: 110
effective length of query: 653
effective length of database: 14,082,258
effective search space: 9195714474
effective search space used: 9195714474
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.