Search of human proteins with 219842319

Search of human proteins with 219842319

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219842319 Bardet-Biedl syndrome 2 protein [Homo sapiens]
         (721 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219842319 Bardet-Biedl syndrome 2 protein [Homo sapiens]          1435   0.0  
gi|29029557 Bardet-Biedl syndrome 7 protein isoform a [Homo sapi...    48   3e-05
gi|29029555 Bardet-Biedl syndrome 7 protein isoform b [Homo sapi...    48   3e-05
gi|28395045 Bardet-Biedl syndrome 1 [Homo sapiens]                     36   0.14 
gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]                35   0.24 
gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]                35   0.24 
gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]                35   0.24 
gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens]         34   0.54 
gi|21361805 integrin alpha FG-GAP repeat containing 2 [Homo sapi...    33   0.93 
gi|100814339 coiled-coil domain containing 146 [Homo sapiens]          32   1.6  
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi...    32   2.7  
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]    32   2.7  
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]    32   2.7  
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]    32   2.7  
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]     32   2.7  
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]    32   2.7  
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi...    32   2.7  
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]    32   2.7  
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi...    32   2.7  
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H...    32   2.7  
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho...    32   2.7  
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H...    32   2.7  
gi|9910352 SH3-domain GRB2-like endophilin B2 [Homo sapiens]           31   3.5  
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H...    31   4.6  
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H...    31   4.6  
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]              31   4.6  
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]             31   4.6  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            31   4.6  
gi|32189376 thyroid hormone receptor interactor 4 [Homo sapiens]       30   6.0  
gi|124028510 WD40-repeat protein upregulated in HCC isoform c [H...    30   6.0  

>gi|219842319 Bardet-Biedl syndrome 2 protein [Homo sapiens]
          Length = 721

 Score = 1435 bits (3715), Expect = 0.0
 Identities = 721/721 (100%), Positives = 721/721 (100%)

Query: 1   MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS 60
           MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS
Sbjct: 1   MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS 60

Query: 61  PLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA 120
           PLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA
Sbjct: 61  PLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA 120

Query: 121 NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL 180
           NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL
Sbjct: 121 NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL 180

Query: 181 VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS 240
           VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS
Sbjct: 181 VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS 240

Query: 241 KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD 300
           KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD
Sbjct: 241 KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD 300

Query: 301 GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK 360
           GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK
Sbjct: 301 GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK 360

Query: 361 AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE 420
           AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE
Sbjct: 361 AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE 420

Query: 421 GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR 480
           GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR
Sbjct: 421 GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR 480

Query: 481 FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN 540
           FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN
Sbjct: 481 FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN 540

Query: 541 GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV 600
           GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV
Sbjct: 541 GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV 600

Query: 601 DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI 660
           DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI
Sbjct: 601 DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI 660

Query: 661 RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS 720
           RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS
Sbjct: 661 RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS 720

Query: 721 S 721
           S
Sbjct: 721 S 721


>gi|29029557 Bardet-Biedl syndrome 7 protein isoform a [Homo
           sapiens]
          Length = 715

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 63/279 (22%), Positives = 116/279 (41%), Gaps = 31/279 (11%)

Query: 147 FNH--EGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIV--AEMTE 202
           +NH  +  D  + ++GD +N +     +   +   ++  +D  +RV +  +++   E+  
Sbjct: 129 YNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDVMYAVEVPG 188

Query: 203 TEIVTSLCPMYGSRFG----YALSNGTVGVYDKTS----RYWRI---KSKNHAMSIHAFD 251
              V +L    G   G    +  S+G + +   T+    R W I   K +   + I +FD
Sbjct: 189 PPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGGILCIDSFD 248

Query: 252 LNSDGVNELITGWSNGKVDARS-DRTGEVI--FKDNFSSAIAGVVEGDYRMDGHIQLICC 308
           +  DGV +L+ G  +G V+  S D   E +  F    S ++  +  G    D + +++  
Sbjct: 249 IVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKDSYDEIVVS 308

Query: 309 SVDGEIRGYL---------PGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENA 359
           +  G + G           PG  E++ N    +    L  EL   +  +L E  NY++++
Sbjct: 309 TYSGWVTGLTTEPIHKESGPG-EELKINQEMQNKISSLRNELEHLQYKVLQERENYQQSS 367

Query: 360 KAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTA 398
           +   +S    A    GI    T      S SL  E QTA
Sbjct: 368 Q---SSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTA 403


>gi|29029555 Bardet-Biedl syndrome 7 protein isoform b [Homo
           sapiens]
          Length = 672

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 63/279 (22%), Positives = 116/279 (41%), Gaps = 31/279 (11%)

Query: 147 FNH--EGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIV--AEMTE 202
           +NH  +  D  + ++GD +N +     +   +   ++  +D  +RV +  +++   E+  
Sbjct: 129 YNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDVMYAVEVPG 188

Query: 203 TEIVTSLCPMYGSRFG----YALSNGTVGVYDKTS----RYWRI---KSKNHAMSIHAFD 251
              V +L    G   G    +  S+G + +   T+    R W I   K +   + I +FD
Sbjct: 189 PPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGGILCIDSFD 248

Query: 252 LNSDGVNELITGWSNGKVDARS-DRTGEVI--FKDNFSSAIAGVVEGDYRMDGHIQLICC 308
           +  DGV +L+ G  +G V+  S D   E +  F    S ++  +  G    D + +++  
Sbjct: 249 IVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKDSYDEIVVS 308

Query: 309 SVDGEIRGYL---------PGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENA 359
           +  G + G           PG  E++ N    +    L  EL   +  +L E  NY++++
Sbjct: 309 TYSGWVTGLTTEPIHKESGPG-EELKINQEMQNKISSLRNELEHLQYKVLQERENYQQSS 367

Query: 360 KAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTA 398
           +   +S    A    GI    T      S SL  E QTA
Sbjct: 368 Q---SSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTA 403


>gi|28395045 Bardet-Biedl syndrome 1 [Homo sapiens]
          Length = 593

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 29/191 (15%)

Query: 49  NQHVSASRVFQSPLESDVSL---LNINQAVSCLTAGVLNPEL---GYDALLVGTQTNLLA 102
           NQH S S   Q+ + +  +L   L    AVSCL  G  N EL     +A  +  + +L +
Sbjct: 187 NQHKSNSIKRQTVITTMTTLKKNLADEDAVSCLVLGTENKELLVLDPEAFTILAKMSLPS 246

Query: 103 YDVY----NNSDLFYREVADGANAIVLGTLGDISSP-------------------LAIIG 139
             V+       D+ +R  A   N  +     D   P                   L +  
Sbjct: 247 VPVFLEVSGQFDVEFRLAAACRNGNIYILRRDSKHPKYCIELSAQPVGLIRVHKVLVVGS 306

Query: 140 GNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIVAE 199
              +L GF H+G  L+       + ++ L +    G + ++ G  + ++R++++  ++  
Sbjct: 307 TQDSLHGFTHKGKKLWTVQMPAAILTMNLLEQHSRGLQAVMAGLANGEVRIYRDKALLNV 366

Query: 200 MTETEIVTSLC 210
           +   + VTSLC
Sbjct: 367 IHTPDAVTSLC 377


>gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]
          Length = 350

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 336 DLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNET 395
           ++ RE+ +  ++   +LR+  E  +AE A+    ++ +   +P +    T     +GN T
Sbjct: 49  EMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNT 108

Query: 396 QTAHTELRISTSNDTIIRAVLIFAEGIFT 424
              H E+   T+N T     ++F+E + T
Sbjct: 109 IHVHREIHKITNNQT---GQMVFSETVIT 134


>gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]
          Length = 350

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 336 DLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNET 395
           ++ RE+ +  ++   +LR+  E  +AE A+    ++ +   +P +    T     +GN T
Sbjct: 49  EMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNT 108

Query: 396 QTAHTELRISTSNDTIIRAVLIFAEGIFT 424
              H E+   T+N T     ++F+E + T
Sbjct: 109 IHVHREIHKITNNQT---GQMVFSETVIT 134


>gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]
          Length = 350

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 336 DLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNET 395
           ++ RE+ +  ++   +LR+  E  +AE A+    ++ +   +P +    T     +GN T
Sbjct: 49  EMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNT 108

Query: 396 QTAHTELRISTSNDTIIRAVLIFAEGIFT 424
              H E+   T+N T     ++F+E + T
Sbjct: 109 IHVHREIHKITNNQT---GQMVFSETVIT 134


>gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens]
          Length = 547

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 4/51 (7%)

Query: 356 EENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRIST 406
           E N K E++ PL+  DG R  +PA+ R  +T S+    +TQT   + R S+
Sbjct: 313 ENNGKEEVSKPLDIPDGRRAPLPAHYRSSSTRSI----DTQTPSVQERSSS 359


>gi|21361805 integrin alpha FG-GAP repeat containing 2 [Homo
           sapiens]
          Length = 447

 Score = 33.1 bits (74), Expect = 0.93
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 162 NVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEI 196
           N   + + D DGDG +EL+VG  D  +R F+ +E+
Sbjct: 126 NTKVMLISDIDGDGCRELVVGYTDRVVRAFRWEEL 160


>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
          Length = 955

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 11/84 (13%)

Query: 319 PGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAKAELASPLNEAD------G 372
           PG  E +  ++  S E+ L +E+ QKK    LE++N  E+  ++    L E        G
Sbjct: 168 PGEMEKKMKILRESTEE-LRKEIMQKK----LEIKNLREDLASKQKQLLKEQKELEELLG 222

Query: 373 HRGIIPANTRLHTTLSVSLGNETQ 396
           H+ ++      H T+ V +G E +
Sbjct: 223 HQVVLKDEVAHHQTIPVQIGKEIE 246


>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
           sapiens]
          Length = 781

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
          Length = 611

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
          Length = 829

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
          Length = 435

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
          Length = 633

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
          Length = 423

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
           sapiens]
          Length = 585

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
          Length = 882

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
           sapiens]
          Length = 560

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 534 CFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEEL 593
           C  +L +  H  +K  +S EI    +++D     +Q   S F     Q+ A       +L
Sbjct: 213 CSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG----QL 268

Query: 594 RKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
            +   + +E   + +++   +A H       L+ A DAR  RD + M SR
Sbjct: 269 GRARAETEEL--IRERVRQVVA-HVRAQERELLEAVDARYQRDYEEMASR 315


>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
            sapiens]
          Length = 1482

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 566  DIIQSMASFFAIEDLQ----VEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLI 621
            D IQ+   +  ++DL+    V  D PV  EELR++ ++V   HS  +K S      ++  
Sbjct: 967  DEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCY 1026

Query: 622  RSLLVGAEDARLMRDMKTMKSRYME----LYDLNRDLL 655
              L V    A    D  T +SR+ME    LY  + +LL
Sbjct: 1027 TLLEVLCPCADAGSD-STKRSRWMEKALGLYQCDTELL 1063


>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
            sapiens]
          Length = 1539

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 566  DIIQSMASFFAIEDLQ----VEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLI 621
            D IQ+   +  ++DL+    V  D PV  EELR++ ++V   HS  +K S      ++  
Sbjct: 1024 DEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCY 1083

Query: 622  RSLLVGAEDARLMRDMKTMKSRYME----LYDLNRDLL 655
              L V    A    D  T +SR+ME    LY  + +LL
Sbjct: 1084 TLLEVLCPCADAGSD-STKRSRWMEKALGLYQCDTELL 1120


>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
            sapiens]
          Length = 1570

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 566  DIIQSMASFFAIEDLQ----VEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLI 621
            D IQ+   +  ++DL+    V  D PV  EELR++ ++V   HS  +K S      ++  
Sbjct: 1055 DEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCY 1114

Query: 622  RSLLVGAEDARLMRDMKTMKSRYME----LYDLNRDLL 655
              L V    A    D  T +SR+ME    LY  + +LL
Sbjct: 1115 TLLEVLCPCADAGSD-STKRSRWMEKALGLYQCDTELL 1151


>gi|9910352 SH3-domain GRB2-like endophilin B2 [Homo sapiens]
          Length = 395

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 34/136 (25%), Positives = 52/136 (38%), Gaps = 23/136 (16%)

Query: 378 PANTRLHTTLSVSLGNETQTAHTELRIS-TSNDTIIRAVLIFAEGIFTGESHVVH-PSIH 435
           P N  L  + S    +E   A  ELR++ T  D       +  EGI    +HV H   +H
Sbjct: 197 PRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGI--SSTHVNHLRCLH 254

Query: 436 NLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPRFSMYALTSLDPASEP 495
                                +K+   Y +    H+ +  +QL RF    + + +PAS P
Sbjct: 255 EF-------------------VKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPP 295

Query: 496 ISYVNFTIAERAQRVV 511
           +S  + T A     VV
Sbjct: 296 LSSTSPTTAAATMPVV 311


>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
            sapiens]
          Length = 1379

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 566  DIIQSMASFFAIEDLQ----VEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLI 621
            D IQ+   +  ++DL+    V  D PV  EELR++ ++V   HS  +K S      ++  
Sbjct: 970  DEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCY 1029

Query: 622  RSLLVGAEDARLMRDMKTMKSRYME----LYDLNRDLL 655
              L V    A    D  T +SR+ME    LY  + +LL
Sbjct: 1030 TLLEVLCPCADAGSD-STKRSRWMEKELGLYKSDTELL 1066


>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
            sapiens]
          Length = 1560

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 566  DIIQSMASFFAIEDLQ----VEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLI 621
            D IQ+   +  ++DL+    V  D PV  EELR++ ++V   HS  +K S      ++  
Sbjct: 1037 DEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCY 1096

Query: 622  RSLLVGAEDARLMRDMKTMKSRYME----LYDLNRDLL 655
              L V    A    D  T +SR+ME    LY  + +LL
Sbjct: 1097 TLLEVLCPCADAGSD-STKRSRWMEKELGLYKSDTELL 1133


>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
          Length = 849

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 27/132 (20%), Positives = 58/132 (43%), Gaps = 17/132 (12%)

Query: 584 ADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
           + F V +EE+R ++++VDE                ++I++L+    D   +  +   KS 
Sbjct: 465 SSFRVPYEEIRMMILEVDETRLA-----------ESMIQNLIKHLPDQEQLNSLSQFKSE 513

Query: 644 YMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVI-TACRDAI 702
           Y  L +  +     + +  +N   L   L A+   +Q   ++   KP    + TAC +  
Sbjct: 514 YSNLCEPEQ-----FVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIK 568

Query: 703 RSNNINTLFKIM 714
           +S + + L +++
Sbjct: 569 KSKSFSKLLELV 580


>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
          Length = 1193

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 27/132 (20%), Positives = 58/132 (43%), Gaps = 17/132 (12%)

Query: 584 ADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSR 643
           + F V +EE+R ++++VDE                ++I++L+    D   +  +   KS 
Sbjct: 728 SSFRVPYEEIRMMILEVDETRLA-----------ESMIQNLIKHLPDQEQLNSLSQFKSE 776

Query: 644 YMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVI-TACRDAI 702
           Y  L +  +     + +  +N   L   L A+   +Q   ++   KP    + TAC +  
Sbjct: 777 YSNLCEPEQ-----FVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIK 831

Query: 703 RSNNINTLFKIM 714
           +S + + L +++
Sbjct: 832 KSKSFSKLLELV 843


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 21/158 (13%)

Query: 532 QVCFTSLRNGGHLHIKIKLS---GEITINTDDID---------LAGDIIQSMASFFAIED 579
           +V  T LR    L   +  S   G   INTD++          LA  ++  +A     ++
Sbjct: 781 EVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILA-----KN 835

Query: 580 LQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKT 639
           L  E D     EE R +  K+ E  +  ++L A++ +    I   LVG E+ R+++ M  
Sbjct: 836 LHKEVDS--ICEEFRSISRKIYEKPNSIEEL-AELREWMKGIPERLVGLEE-RIVKVMDD 891

Query: 640 MKSRYMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQ 677
            +     LY+L+ D  N   I  N  +++LG ++ V Q
Sbjct: 892 YQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQ 929


>gi|32189376 thyroid hormone receptor interactor 4 [Homo sapiens]
          Length = 581

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 16/114 (14%)

Query: 305 LICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENA-KAEL 363
           LIC  +  E  G   G     G L+ T  EQD+++  S K Q LL +L +  EN+ K ++
Sbjct: 185 LICGRIVCEQEG--SGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDI 242

Query: 364 ASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLI 417
           ++        + ++P     H  L +  G E    H +  +     +I R  +I
Sbjct: 243 ST--------KDLLP-----HQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVI 283


>gi|124028510 WD40-repeat protein upregulated in HCC isoform c [Homo
           sapiens]
          Length = 552

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 8/61 (13%)

Query: 231 KTSRYWRIKSKNHAMSI-------HAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKD 283
           K  R W   S    + I       H  D   DG   +I+ W++GK+ A +  TG +++  
Sbjct: 286 KDIRVWHTSSNRELLRITVPNMTCHGIDFMRDG-KSIISAWNDGKIRAFAPETGRLMYVI 344

Query: 284 N 284
           N
Sbjct: 345 N 345


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,957,545
Number of Sequences: 37866
Number of extensions: 1057498
Number of successful extensions: 2681
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2657
Number of HSP's gapped (non-prelim): 46
length of query: 721
length of database: 18,247,518
effective HSP length: 110
effective length of query: 611
effective length of database: 14,082,258
effective search space: 8604259638
effective search space used: 8604259638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.