Guide to the Human Genome
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Search of human proteins with 217416386

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217416386 aarF domain containing kinase 4 isoform b [Homo
sapiens]
         (503 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217416386 aarF domain containing kinase 4 isoform b [Homo sap...  1028   0.0  
gi|27363457 aarF domain containing kinase 4 isoform a [Homo sapi...  1008   0.0  
gi|34147522 chaperone, ABC1 activity of bc1 complex like precurs...   511   e-145
gi|40254938 aarF domain containing kinase 1 isoform a [Homo sapi...    79   1e-14
gi|41393593 aarF domain containing kinase 5 [Homo sapiens]             77   3e-14
gi|217035081 aarF domain containing kinase 1 isoform b [Homo sap...    71   2e-12
gi|32261307 aarF domain containing kinase 2 [Homo sapiens]             44   4e-04
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]      34   0.27 
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]      34   0.27 
gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens]      34   0.27 
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    32   1.0  
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    32   1.0  
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]            32   1.3  
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]            32   1.3  
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]            32   1.3  
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ...    32   1.8  
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ...    32   1.8  
gi|89111943 Kruppel-like factor 8 isoform 1 [Homo sapiens]             31   2.3  
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]               31   2.3  
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]               31   2.3  
gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b...    31   2.3  
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a...    31   2.3  
gi|239748099 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|226530795 Kruppel-like factor 8 isoform 2 [Homo sapiens]            31   3.0  
gi|55743138 ribosomal protein S6 kinase, 90kDa, polypeptide 4 is...    31   3.0  
gi|4506735 ribosomal protein S6 kinase, 90kDa, polypeptide 4 iso...    31   3.0  
gi|121582655 ankyrin repeat domain 35 [Homo sapiens]                   31   3.0  
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        30   3.9  
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        30   3.9  
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         30   3.9  

>gi|217416386 aarF domain containing kinase 4 isoform b [Homo
           sapiens]
          Length = 503

 Score = 1028 bits (2658), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60
           MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR
Sbjct: 1   MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60

Query: 61  RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120
           RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL
Sbjct: 61  RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120

Query: 121 QSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIG 180
           QSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIG
Sbjct: 121 QSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIG 180

Query: 181 QVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQEL 240
           QVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQEL
Sbjct: 181 QVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQEL 240

Query: 241 AWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQD 300
           AWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQD
Sbjct: 241 AWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQD 300

Query: 301 LRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHY 360
           LRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHY
Sbjct: 301 LRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHY 360

Query: 361 IEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGE 420
           IEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGE
Sbjct: 361 IEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGE 420

Query: 421 TARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWA 480
           TARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWA
Sbjct: 421 TARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWA 480

Query: 481 SRQPDAATAGSLPTKGDSWVDPS 503
           SRQPDAATAGSLPTKGDSWVDPS
Sbjct: 481 SRQPDAATAGSLPTKGDSWVDPS 503


>gi|27363457 aarF domain containing kinase 4 isoform a [Homo
           sapiens]
          Length = 544

 Score = 1008 bits (2606), Expect = 0.0
 Identities = 503/544 (92%), Positives = 503/544 (92%), Gaps = 41/544 (7%)

Query: 1   MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60
           MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR
Sbjct: 1   MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60

Query: 61  RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120
           RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL
Sbjct: 61  RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120

Query: 121 QS-----------------------------------------DNSFISPQLQHIFERVR 139
           QS                                         DNSFISPQLQHIFERVR
Sbjct: 121 QSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR 180

Query: 140 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY 199
           QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY
Sbjct: 181 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY 240

Query: 200 PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL 259
           PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL
Sbjct: 241 PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL 300

Query: 260 LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE 319
           LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE
Sbjct: 301 LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE 360

Query: 320 FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS 379
           FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS
Sbjct: 361 FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS 420

Query: 380 RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP 439
           RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP
Sbjct: 421 RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP 480

Query: 440 PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW 499
           PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW
Sbjct: 481 PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW 540

Query: 500 VDPS 503
           VDPS
Sbjct: 541 VDPS 544


>gi|34147522 chaperone, ABC1 activity of bc1 complex like precursor
           [Homo sapiens]
          Length = 647

 Score =  511 bits (1315), Expect = e-145
 Identities = 266/512 (51%), Positives = 337/512 (65%), Gaps = 44/512 (8%)

Query: 11  GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQD-GPGRGLGEEDIRRAREARPR- 68
           G  GQ    +G   G L   P       G   + F+QD  P  GL  EDI +AR+A+ R 
Sbjct: 129 GFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARP 188

Query: 69  --KTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSM----PGGRLQ- 121
             K  +  LS+ +RERKVP +RI RLANFGGLAVGLG G LAE+AKKS+    P G+   
Sbjct: 189 ENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAV 248

Query: 122 -----------------------------------SDNSFISPQLQHIFERVRQSADFMP 146
                                               D++FI+P L  IFERVRQSADFMP
Sbjct: 249 LGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMP 308

Query: 147 RWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSI 206
             QM++ L  +LG +W+ K+   EE PFAAASIGQVH   ++ G EVA+KIQYPG+AQSI
Sbjct: 309 LKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSI 368

Query: 207 QSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFF 266
            SDV NL+AVL MS  LP GLF E  +  L++ELA ECDY+REAACA+ FR LL   PFF
Sbjct: 369 NSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFF 428

Query: 267 RVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTD 326
            VP +V ELC+  VL  EL  G PLDQ +GLSQ++RN+IC+ +L LCLRELFEF FMQTD
Sbjct: 429 YVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTD 488

Query: 327 PNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLT 386
           PNW+NF YD   H+V LLDFGA+RE+   FTD YI++++AAAD DR+ V  KS ++KFLT
Sbjct: 489 PNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLT 548

Query: 387 GFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYA 446
           G+E K   DAH++A++ILGE FA+  P+DFG+  T  +I +LIPV+LRHRL PPPEETY+
Sbjct: 549 GYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYS 608

Query: 447 LHRKLAGAFLACAHLRAHIACRDLFQDTYHRY 478
           LHRK+ G+FL C+ L+A   C+ +F++ Y  Y
Sbjct: 609 LHRKMGGSFLICSKLKARFPCKAMFEEAYSNY 640


>gi|40254938 aarF domain containing kinase 1 isoform a [Homo
           sapiens]
          Length = 523

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 67/244 (27%), Positives = 112/244 (45%), Gaps = 14/244 (5%)

Query: 149 QMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQS 208
           ++ +V+ E+LG++      S ++ P   AS+ QVH+ +L DG  VAVK+Q+P +      
Sbjct: 129 EIRQVIREDLGKEIHDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSK 188

Query: 209 DVQNLLAVLKMSAALPAGLFAEQSLQALQQE----LAWECDYRREAACAQNFRQLLANDP 264
           D+  L+ VL ++      LF E     L  E    L  E D+  E   A+   Q+L +  
Sbjct: 189 DIL-LMEVLVLAV---KQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFD 244

Query: 265 FFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDL--RNQICFQLLTLCLRELFEFRF 322
           F +VP +  +L T RVL ME   G  ++    + ++    N+I   L  +    +F   F
Sbjct: 245 FLKVPRIHWDLSTERVLLMEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGF 304

Query: 323 MQTDPNWANFLY----DASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQK 378
           +  DP+  N L          ++ LLD G  +    EF  +Y  + ++    D   V + 
Sbjct: 305 VHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEY 364

Query: 379 SRDL 382
           S+ L
Sbjct: 365 SQRL 368


>gi|41393593 aarF domain containing kinase 5 [Homo sapiens]
          Length = 580

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 5/180 (2%)

Query: 173 PFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQS 232
           P AAAS+ QVH+  L DGT VAVK+QY  +      D+  L  +L++   +         
Sbjct: 205 PIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWV 264

Query: 233 LQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLD 292
           LQ L+  LA E D+  E   A+   + LA+ P+  VP V  +  + RVL  +   G  ++
Sbjct: 265 LQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVN 324

Query: 293 QCQGL-SQDLR-NQICFQLLTLCLRELFEFRFMQTDPNWANFLY---DASSHQVTLLDFG 347
             + + SQ L  + I  +L+     ++F   F+ +DP+  N L         ++ LLD G
Sbjct: 325 DVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHG 384


>gi|217035081 aarF domain containing kinase 1 isoform b [Homo
           sapiens]
          Length = 455

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 14/225 (6%)

Query: 168 SLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGL 227
           S ++ P   AS+ QVH+ +L DG  VAVK+Q+P +      D+  L+ VL ++      L
Sbjct: 80  SFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDIL-LMEVLVLAV---KQL 135

Query: 228 FAEQSLQALQQE----LAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGM 283
           F E     L  E    L  E D+  E   A+   Q+L +  F +VP +  +L T RVL M
Sbjct: 136 FPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLM 195

Query: 284 ELAGGVPLDQCQGLSQDL--RNQICFQLLTLCLRELFEFRFMQTDPNWANFLY----DAS 337
           E   G  ++    + ++    N+I   L  +    +F   F+  DP+  N L        
Sbjct: 196 EFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTG 255

Query: 338 SHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDL 382
             ++ LLD G  +    EF  +Y  + ++    D   V + S+ L
Sbjct: 256 KAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRL 300


>gi|32261307 aarF domain containing kinase 2 [Homo sapiens]
          Length = 626

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 6/170 (3%)

Query: 175 AAASIGQV--HQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPA--GLFAE 230
           A  S  QV  HQ    +   VAVK+ +PG+   +  D+  +    ++   LP    L   
Sbjct: 288 AGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLP 347

Query: 231 QSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVP 290
           + ++  ++ +  + D R EA   ++F+    N    + P  ++   T  VL       VP
Sbjct: 348 EIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVP 407

Query: 291 LDQCQ--GLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASS 338
           +   Q  G+  DL+ +I    + + L+ +F   F+  D +  N L   ++
Sbjct: 408 VSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGAN 457


>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
          Length = 4022

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 20/133 (15%)

Query: 311 TLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADG 370
           T     LF++R  + +   A F+ D++ H+ T  +    + FG  + D+   +   +  G
Sbjct: 492 TYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKG 551

Query: 371 ---DRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETA-RRIQ 426
               +D    KS DL  +    TK+                   GP DF    +A  RI 
Sbjct: 552 STNQQDFSSGKSEDLGTVQEKSTKSL----------------VIGPLDFRLDSSAVHRIL 595

Query: 427 DLIPVLLRHRLCP 439
            +I   L H   P
Sbjct: 596 KMIVCALEHEYEP 608


>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
          Length = 3997

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 20/133 (15%)

Query: 311 TLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADG 370
           T     LF++R  + +   A F+ D++ H+ T  +    + FG  + D+   +   +  G
Sbjct: 492 TYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKG 551

Query: 371 ---DRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETA-RRIQ 426
               +D    KS DL  +    TK+                   GP DF    +A  RI 
Sbjct: 552 STNQQDFSSGKSEDLGTVQEKSTKSL----------------VIGPLDFRLDSSAVHRIL 595

Query: 427 DLIPVLLRHRLCP 439
            +I   L H   P
Sbjct: 596 KMIVCALEHEYEP 608


>gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens]
          Length = 863

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 20/133 (15%)

Query: 311 TLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADG 370
           T     LF++R  + +   A F+ D++ H+ T  +    + FG  + D+   +   +  G
Sbjct: 492 TYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKG 551

Query: 371 ---DRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETA-RRIQ 426
               +D    KS DL  +    TK+                   GP DF    +A  RI 
Sbjct: 552 STNQQDFSSGKSEDLGTVQEKSTKSL----------------VIGPLDFRLDSSAVHRIL 595

Query: 427 DLIPVLLRHRLCP 439
            +I   L H   P
Sbjct: 596 KMIVCALEHEYEP 608


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
            [Homo sapiens]
          Length = 1481

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 45/183 (24%), Positives = 69/183 (37%), Gaps = 27/183 (14%)

Query: 53   GLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAK 112
            G   E ++ +  A P+  P P   +      +  + I++  N   LAV L L  L     
Sbjct: 1073 GTSTEPVKNSSPAPPQ--PAPGKVESGAGDAIGLADITQQLNQSELAVLLNL--LQSQTD 1128

Query: 113  KSMPGGRLQSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEV 172
             S+P    Q  N   +P++Q   E + QS        +     ++   +  A   SL+E 
Sbjct: 1129 LSIPQ-MAQLLNIHSNPEMQQQLEALNQSIS-----ALTEATSQQQDSETMAPEESLKEA 1182

Query: 173  PFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVL---KMSAALPAGLFA 229
            P A   +    Q  L               A S  +D+QN+LAVL    M    PAG   
Sbjct: 1183 PSAPVILPSAEQTTLE--------------ASSTPADMQNILAVLLSQLMKTQEPAGSLE 1228

Query: 230  EQS 232
            E +
Sbjct: 1229 ENN 1231


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
            [Homo sapiens]
          Length = 1490

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 45/183 (24%), Positives = 69/183 (37%), Gaps = 27/183 (14%)

Query: 53   GLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAK 112
            G   E ++ +  A P+  P P   +      +  + I++  N   LAV L L  L     
Sbjct: 1073 GTSTEPVKNSSPAPPQ--PAPGKVESGAGDAIGLADITQQLNQSELAVLLNL--LQSQTD 1128

Query: 113  KSMPGGRLQSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEV 172
             S+P    Q  N   +P++Q   E + QS        +     ++   +  A   SL+E 
Sbjct: 1129 LSIPQ-MAQLLNIHSNPEMQQQLEALNQSIS-----ALTEATSQQQDSETMAPEESLKEA 1182

Query: 173  PFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVL---KMSAALPAGLFA 229
            P A   +    Q  L               A S  +D+QN+LAVL    M    PAG   
Sbjct: 1183 PSAPVILPSAEQTTLE--------------ASSTPADMQNILAVLLSQLMKTQEPAGSLE 1228

Query: 230  EQS 232
            E +
Sbjct: 1229 ENN 1231


>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)

Query: 11  GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKT 70
           G+  Q  +T  W    L P   RWGPC G         G GRG G    RR RE    +T
Sbjct: 404 GSAIQALETSAW---VLPPSTGRWGPCRGC--------GRGRGRGRGRGRRPRELGTEET 452


>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)

Query: 11  GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKT 70
           G+  Q  +T  W    L P   RWGPC G         G GRG G    RR RE    +T
Sbjct: 404 GSAIQALETSAW---VLPPSTGRWGPCRGC--------GRGRGRGRGRGRRPRELGTEET 452


>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)

Query: 11  GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKT 70
           G+  Q  +T  W    L P   RWGPC G         G GRG G    RR RE    +T
Sbjct: 404 GSAIQALETSAW---VLPPSTGRWGPCRGC--------GRGRGRGRGRGRRPRELGTEET 452


>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
           sapiens]
          Length = 647

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 27/101 (26%)

Query: 7   GLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKF-------YQDGPGR---GLGE 56
           GL RGT  Q   T  W   AL   P      GG+W  +F       +QDG  R   G G 
Sbjct: 317 GLARGTAPQPAST--W---ALAARPR----AGGTWTSRFEAQRGCAHQDGQRRTRDGAGN 367

Query: 57  EDIRRAR-------EARPRKTPRPQLSDRSRERKVPASRIS 90
                AR         RPR+ PR  L +  + R+ P +R S
Sbjct: 368 HASEPARVWSPPPRRQRPRRLPRASLQEEPK-RRPPCARPS 407


>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
           sapiens]
          Length = 647

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 27/101 (26%)

Query: 7   GLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKF-------YQDGPGR---GLGE 56
           GL RGT  Q   T  W   AL   P      GG+W  +F       +QDG  R   G G 
Sbjct: 317 GLARGTAPQPAST--W---ALAARPR----AGGTWTSRFEAQRGCAHQDGQRRTRDGAGN 367

Query: 57  EDIRRAR-------EARPRKTPRPQLSDRSRERKVPASRIS 90
                AR         RPR+ PR  L +  + R+ P +R S
Sbjct: 368 HASEPARVWSPPPRRQRPRRLPRASLQEEPK-RRPPCARPS 407


>gi|89111943 Kruppel-like factor 8 isoform 1 [Homo sapiens]
          Length = 359

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 43/183 (23%), Positives = 69/183 (37%), Gaps = 42/183 (22%)

Query: 67  PRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSDNSF 126
           P + P+PQ S ++       S +S  AN   +                 PG  L S  S 
Sbjct: 107 PIRPPKPQSSPQTLVVSTSTSDMSTSANIPTVLT---------------PGSVLTSSQST 151

Query: 127 ISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGL 186
            S Q+ H+   +   +  +P                  K+  L+ +P    S+  V+  L
Sbjct: 152 GSQQILHVIHTIPSVS--LPN-----------------KMGGLKTIPVVVQSLPMVYTTL 192

Query: 187 LRDGTEVAVKIQYPG----IAQSIQSDVQNLLAVLKMS----AALPAGLFAEQSLQALQQ 238
             DG   A+ +   G     A S++ D  ++  +   S    + + +G  A QSLQ LQQ
Sbjct: 193 PADGGPAAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQ 252

Query: 239 ELA 241
           E A
Sbjct: 253 EPA 255


>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
          Length = 676

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 44  KFYQDGPGRGLGEED--IRRAREARPRKTPRPQLSDRSRERK 83
           KF Q  PGRG G +D  +R + +   R  P    S R R+RK
Sbjct: 550 KFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRK 591


>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
          Length = 678

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 44  KFYQDGPGRGLGEED--IRRAREARPRKTPRPQLSDRSRERK 83
           KF Q  PGRG G +D  +R + +   R  P    S R R+RK
Sbjct: 552 KFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRK 593


>gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b
           [Homo sapiens]
          Length = 549

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 304 QICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTD 358
           QI    + L L  L +   +  D    N L D++ H V L DFG S+EF  + T+
Sbjct: 155 QIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGH-VVLTDFGLSKEFVADETE 208


>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
           [Homo sapiens]
          Length = 802

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 304 QICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTD 358
           QI    + L L  L +   +  D    N L D++ H V L DFG S+EF  + T+
Sbjct: 155 QIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGH-VVLTDFGLSKEFVADETE 208


>gi|239748099 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 11/89 (12%)

Query: 13  GGQLGQTVGWPCGALGPGPH-------RWGPCGGSWAQKFY----QDGPGRGLGEEDIRR 61
           G +L  T  WP G L  GP        R    GG  A++      + G  R L  E  R 
Sbjct: 85  GARLQATRTWPAGILEGGPQVAARGGGRGWEGGGLGARRAVTAARRGGASRPLAGEPWRE 144

Query: 62  AREARPRKTPRPQLSDRSRERKVPASRIS 90
           A   RP++ P+   +  SR   + + R+S
Sbjct: 145 AARRRPQQCPQWGRARESRSAALASPRVS 173


>gi|226530795 Kruppel-like factor 8 isoform 2 [Homo sapiens]
          Length = 257

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 42/181 (23%), Positives = 68/181 (37%), Gaps = 42/181 (23%)

Query: 67  PRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSDNSF 126
           P + P+PQ S ++       S +S  AN   +                 PG  L S  S 
Sbjct: 107 PIRPPKPQSSPQTLVVSTSTSDMSTSANIPTVLT---------------PGSVLTSSQST 151

Query: 127 ISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGL 186
            S Q+ H+   +   +  +P                  K+  L+ +P    S+  V+  L
Sbjct: 152 GSQQILHVIHTIPSVS--LPN-----------------KMGGLKTIPVVVQSLPMVYTTL 192

Query: 187 LRDGTEVAVKIQYPG----IAQSIQSDVQNLLAVLKMS----AALPAGLFAEQSLQALQQ 238
             DG   A+ +   G     A S++ D  ++  +   S    + + +G  A QSLQ LQQ
Sbjct: 193 PADGGPAAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQ 252

Query: 239 E 239
           E
Sbjct: 253 E 253


>gi|55743138 ribosomal protein S6 kinase, 90kDa, polypeptide 4
           isoform b [Homo sapiens]
          Length = 766

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 310 LTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTE 355
           + L L  L +   +  D    N L D+  H + L DFG S+EF TE
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGH-IVLTDFGLSKEFLTE 189


>gi|4506735 ribosomal protein S6 kinase, 90kDa, polypeptide 4
           isoform a [Homo sapiens]
          Length = 772

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 310 LTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTE 355
           + L L  L +   +  D    N L D+  H + L DFG S+EF TE
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGH-IVLTDFGLSKEFLTE 189


>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
          Length = 1001

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 46/200 (23%), Positives = 80/200 (40%), Gaps = 26/200 (13%)

Query: 41  WAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAV 100
           WA+   Q  P     E   + +RE   +  P     D  +E++VP +R   L   GG   
Sbjct: 550 WAKAGLQVKP-----EVPSQESREGALKAAPGSIKQDEEKEKRVPGARGEPLGALGG--- 601

Query: 101 GLGLGVLAEMAKKSMPGGRLQSDNSFISPQLQHIFERVRQSADFMPRWQM-LRVLEEELG 159
                   E A   +  G+L+ + S +     ++ E + +      R Q  L+ L + L 
Sbjct: 602 --------EKALGGLAKGQLEKEMSVLRLSNSNLLEELGELGRERQRLQRELQSLSQRLQ 653

Query: 160 RDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKM 219
           R++  K  +  ++     S+G +   L  +  E   K++    +QS  S ++ L      
Sbjct: 654 REFVPKPEAQVQLQQLRQSVGLLTNELAME-KEATEKLRKLLASQS--SGLRGLW----- 705

Query: 220 SAALPAGLFAEQSLQALQQE 239
              LPA L  E+S Q+   E
Sbjct: 706 -DCLPADLVGERSAQSKAAE 724


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 54/221 (24%), Positives = 88/221 (39%), Gaps = 29/221 (13%)

Query: 56   EEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSM 115
            EE  RR R+A   +  + Q++  + +R   A   S+ A+F      L   +  E    + 
Sbjct: 1546 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1605

Query: 116  PGGRLQSDNSFISPQLQHIFERVRQSAD-FMPRWQM-------LRVLEEELGRDWQAKVA 167
                   + +    Q Q   ER R+ A+  + RWQ+       LR+  EE+ +      A
Sbjct: 1606 -----LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1660

Query: 168  SL----EEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLA----VLKM 219
                  EE    A   G+  +  +R       +++     Q  +   Q  LA    ++++
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ--RQLAEGTAQQRLAAEQELIRL 1718

Query: 220  SAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLL 260
             A    G   EQ  Q L++ELA     +REAA A   RQ L
Sbjct: 1719 RAETEQG---EQQRQLLEEELA---RLQREAAAATQKRQEL 1753


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 54/221 (24%), Positives = 88/221 (39%), Gaps = 29/221 (13%)

Query: 56   EEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSM 115
            EE  RR R+A   +  + Q++  + +R   A   S+ A+F      L   +  E    + 
Sbjct: 1550 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1609

Query: 116  PGGRLQSDNSFISPQLQHIFERVRQSAD-FMPRWQM-------LRVLEEELGRDWQAKVA 167
                   + +    Q Q   ER R+ A+  + RWQ+       LR+  EE+ +      A
Sbjct: 1610 -----LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1664

Query: 168  SL----EEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLA----VLKM 219
                  EE    A   G+  +  +R       +++     Q  +   Q  LA    ++++
Sbjct: 1665 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ--RQLAEGTAQQRLAAEQELIRL 1722

Query: 220  SAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLL 260
             A    G   EQ  Q L++ELA     +REAA A   RQ L
Sbjct: 1723 RAETEQG---EQQRQLLEEELA---RLQREAAAATQKRQEL 1757


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 54/221 (24%), Positives = 88/221 (39%), Gaps = 29/221 (13%)

Query: 56   EEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSM 115
            EE  RR R+A   +  + Q++  + +R   A   S+ A+F      L   +  E    + 
Sbjct: 1546 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1605

Query: 116  PGGRLQSDNSFISPQLQHIFERVRQSAD-FMPRWQM-------LRVLEEELGRDWQAKVA 167
                   + +    Q Q   ER R+ A+  + RWQ+       LR+  EE+ +      A
Sbjct: 1606 -----LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1660

Query: 168  SL----EEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLA----VLKM 219
                  EE    A   G+  +  +R       +++     Q  +   Q  LA    ++++
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ--RQLAEGTAQQRLAAEQELIRL 1718

Query: 220  SAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLL 260
             A    G   EQ  Q L++ELA     +REAA A   RQ L
Sbjct: 1719 RAETEQG---EQQRQLLEEELA---RLQREAAAATQKRQEL 1753


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,902,791
Number of Sequences: 37866
Number of extensions: 999183
Number of successful extensions: 2633
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2607
Number of HSP's gapped (non-prelim): 49
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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