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Search of human proteins with 217035102
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform
1 [Homo sapiens]
(514 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 1049 0.0
gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 964 0.0
gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 937 0.0
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 397 e-110
gi|150417989 cyclin K isoform 1 [Homo sapiens] 77 5e-14
gi|11386183 WAS protein family, member 2 [Homo sapiens] 73 5e-13
gi|160707881 formin 2 [Homo sapiens] 72 1e-12
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 69 8e-12
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 69 8e-12
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 68 2e-11
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 65 2e-10
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 65 2e-10
gi|210032580 SET domain containing 1B [Homo sapiens] 65 2e-10
gi|157168329 formin 1 [Homo sapiens] 64 3e-10
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 64 3e-10
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 64 3e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 64 3e-10
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 63 6e-10
gi|56549694 enabled homolog isoform a [Homo sapiens] 63 7e-10
gi|39930375 enabled homolog isoform b [Homo sapiens] 63 7e-10
gi|33356148 formin-like 1 [Homo sapiens] 62 2e-09
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 61 2e-09
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 60 4e-09
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 60 4e-09
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 60 4e-09
gi|153792074 proline rich 12 [Homo sapiens] 60 5e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 60 6e-09
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 59 8e-09
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 59 1e-08
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 59 1e-08
>gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform 1
[Homo sapiens]
Length = 514
Score = 1049 bits (2713), Expect = 0.0
Identities = 514/514 (100%), Positives = 514/514 (100%)
Query: 1 MGRPESAGGGSRGPFEGGGRARRAGGIFLTLSILRTRDLPSGAMSEGVDLIDIYADEEFN 60
MGRPESAGGGSRGPFEGGGRARRAGGIFLTLSILRTRDLPSGAMSEGVDLIDIYADEEFN
Sbjct: 1 MGRPESAGGGSRGPFEGGGRARRAGGIFLTLSILRTRDLPSGAMSEGVDLIDIYADEEFN 60
Query: 61 QDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPSPKPNNKTPAILYTYSGL 120
QDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPSPKPNNKTPAILYTYSGL
Sbjct: 61 QDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPSPKPNNKTPAILYTYSGL 120
Query: 121 RNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENS 180
RNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENS
Sbjct: 121 RNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENS 180
Query: 181 VHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDS 240
VHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDS
Sbjct: 181 VHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDS 240
Query: 241 ADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPP 300
ADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPP
Sbjct: 241 ADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPP 300
Query: 301 PPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPY 360
PPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPY
Sbjct: 301 PPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPY 360
Query: 361 NHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAV 420
NHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAV
Sbjct: 361 NHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAV 420
Query: 421 IKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRR 480
IKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRR
Sbjct: 421 IKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRR 480
Query: 481 HRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 514
HRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
Sbjct: 481 HRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 514
>gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform 2
[Homo sapiens]
Length = 471
Score = 964 bits (2492), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 44 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 103
MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS
Sbjct: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
Query: 104 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 163
PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA
Sbjct: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
Query: 164 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV 223
NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV
Sbjct: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV 180
Query: 224 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 283
PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP
Sbjct: 181 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 240
Query: 284 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 343
PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN
Sbjct: 241 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 300
Query: 344 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 403
ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS
Sbjct: 301 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 360
Query: 404 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 463
AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR
Sbjct: 361 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 420
Query: 464 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 514
HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
Sbjct: 421 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 471
>gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform 3
[Homo sapiens]
Length = 462
Score = 937 bits (2421), Expect = 0.0
Identities = 462/471 (98%), Positives = 462/471 (98%), Gaps = 9/471 (1%)
Query: 44 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 103
MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS
Sbjct: 1 MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPS 60
Query: 104 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 163
PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA
Sbjct: 61 PKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRA 120
Query: 164 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV 223
NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR
Sbjct: 121 NGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR----- 175
Query: 224 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 283
IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP
Sbjct: 176 ----IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 231
Query: 284 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 343
PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN
Sbjct: 232 PIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN 291
Query: 344 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 403
ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS
Sbjct: 292 ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVSGAS 351
Query: 404 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 463
AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR
Sbjct: 352 AGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKR 411
Query: 464 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 514
HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH
Sbjct: 412 HRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHERHRDRERDRHH 462
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 397 bits (1019), Expect = e-110
Identities = 255/557 (45%), Positives = 314/557 (56%), Gaps = 107/557 (19%)
Query: 44 MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 98
M++GVD IDIYAD EEFNQ+ E+ DQIDLYDDV++ ++ D DR PP V
Sbjct: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60
Query: 99 RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 158
+ P ++YTY+G +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF
Sbjct: 61 GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114
Query: 159 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 218
ENRANGQSKG+A V V SE S KL++LLP + L+G+ V P +Q LSQFE Q+RK
Sbjct: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174
Query: 219 ECVRVPRG---GIPPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 269
G PP SR + GR A P + P A PP P
Sbjct: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234
Query: 270 RPPSALPLMGLPPPPIPP---------PPPLSSS-----------------FGVPP---- 299
PP P +G P PP PP PPPL+ FG PP
Sbjct: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
Query: 300 ------------PPPGIHYQHLMPPPP------------------RLPPHLAVPPPGAIP 329
PPPG PPPP PPHL PPPGA P
Sbjct: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
Query: 330 PALHLNPAFFPPP-------NATVGPPPDTYMKASAPYNHHGSRDSGPPP-------STV 375
PA H+NPAFFPPP + + GPPP PY+ D GPP + +
Sbjct: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG---DYGPPGREMDTARTPL 409
Query: 376 SEAEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVL 435
SEAEFE+IM RNRAISSSAIS+AVS ASAGDY AIETL+TAI++IKQS+V+ D+RC+VL
Sbjct: 410 SEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVL 469
Query: 436 ISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYF 495
ISSL+DCLHGIE+KSY GS SR R RSRER SRSRE SRRH+ + DRHDDY+
Sbjct: 470 ISSLQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYY 521
Query: 496 QERNREHERHRDRERDR 512
+ER+RE ERHRDR+RDR
Sbjct: 522 RERSRERERHRDRDRDR 538
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/103 (45%), Positives = 51/103 (49%), Gaps = 21/103 (20%)
Query: 261 PPSVLPYFNR--------PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPP 312
PP+ LPY PP P PPP IPPP P G PPPPP + + PP
Sbjct: 467 PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP-----GYPPPPP-TYNPNFPPP 520
Query: 313 PPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVG-----PPP 350
PPRLPP AVPP PP L L PA +PPP G PPP
Sbjct: 521 PPRLPPTHAVPPHP--PPGLGLPPASYPPPAVPPGGQPPVPPP 561
Score = 58.9 bits (141), Expect = 1e-08
Identities = 49/158 (31%), Positives = 64/158 (40%), Gaps = 34/158 (21%)
Query: 229 PPRAHSRDSSDSADGRATPSENLVPSSARVDKPP-SVLPYFNRPPSALPLMGLPPPPIPP 287
PP ++ S ++ + + S + + P LP PP+ LP PP PP
Sbjct: 424 PPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483
Query: 288 PPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP----- 342
PPP VPPPP PPP +PP P PG PP NP F PPP
Sbjct: 484 PPP------VPPPPASF-------PPPAIPP----PTPGYPPPPPTYNPNFPPPPPRLPP 526
Query: 343 -NAT-------VGPPPDTYMKASAPYNHHGSRDSGPPP 372
+A +G PP +Y + P G + PPP
Sbjct: 527 THAVPPHPPPGLGLPPASYPPPAVP---PGGQPPVPPP 561
Score = 56.6 bits (135), Expect = 5e-08
Identities = 35/80 (43%), Positives = 40/80 (50%), Gaps = 10/80 (12%)
Query: 261 PPSVLPYFNRPPSALP--LMGLPPPP------IPPPPP-LSSSFGVPP-PPPGIHYQHLM 310
PP P + PP A+P G PPPP PPPPP L + VPP PPPG+
Sbjct: 485 PPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPAS 544
Query: 311 PPPPRLPPHLAVPPPGAIPP 330
PPP +PP P P IPP
Sbjct: 545 YPPPAVPPGGQPPVPPPIPP 564
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/126 (34%), Positives = 49/126 (38%), Gaps = 45/126 (35%)
Query: 265 LPYFNRPPSALPLMGLPPPPIP---PPPPLSS---------------------------- 293
LP PP A P PPP+P PPPP SS
Sbjct: 396 LPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEG 455
Query: 294 -SFGVPPP---PPGI--HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVG 347
S+G PP PP ++ H+ PP P PP PPP + PP PA PPP
Sbjct: 456 PSYGALPPAYGPPAHLPYHPHVYPPNPPPPP--VPPPPASFPP-----PAI-PPPTPGYP 507
Query: 348 PPPDTY 353
PPP TY
Sbjct: 508 PPPPTY 513
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/85 (36%), Positives = 34/85 (40%), Gaps = 21/85 (24%)
Query: 286 PPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLA----VPPPG----------AIPPA 331
PPPP + PP P H PPP R PP A PPG IPP
Sbjct: 350 PPPPKIPKIETTHPPLPPAH-----PPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPP 404
Query: 332 LHLNPAFFPP--PNATVGPPPDTYM 354
H P PP P+ PPP +YM
Sbjct: 405 AHPAPVHQPPPLPHRPPPPPPSSYM 429
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 253 PSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPP---PPPGIHYQHL 309
P+ PP+ P F PP LP P +PP PP G+PP PPP +
Sbjct: 502 PTPGYPPPPPTYNPNFPPPPPRLP----PTHAVPPHPP--PGLGLPPASYPPPAVPPGGQ 555
Query: 310 MPPPPRLPPHLAVPPPGAI 328
P PP +PP +PP G +
Sbjct: 556 PPVPPPIPPP-GMPPVGGL 573
Score = 35.0 bits (79), Expect = 0.16
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 16/66 (24%)
Query: 247 PSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHY 306
P L P+ A PP P PP++ P +PP PP PP P PPPG
Sbjct: 520 PPPRLPPTHAVPPHPP---PGLGLPPASYPPPAVPPGGQPPVPP-------PIPPPG--- 566
Query: 307 QHLMPP 312
MPP
Sbjct: 567 ---MPP 569
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 73.2 bits (178), Expect = 5e-13
Identities = 67/211 (31%), Positives = 84/211 (39%), Gaps = 30/211 (14%)
Query: 229 PPRAHSRDSSDS--ADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIP 286
PP A D+ G A P + V S + P P PP P PP P P
Sbjct: 269 PPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH----PPPAPPLGSPPGPKPGFAPPPAPPP 324
Query: 287 PPPPLSSSFGVPPPPPGIHY----QHLMPPPPRLPPH--LAVPPPGAIPPALHLNPAFFP 340
PPPP+ G+PPPPP + + P PP PPH A PPP PPA A +P
Sbjct: 325 PPPPM---IGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA-----ADYP 376
Query: 341 PPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRAISSSAISKAVS 400
T+ PPP + AP GPPP + A+ + AI
Sbjct: 377 ----TLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQP------AIPPPLSDTTKP 426
Query: 401 GASAGDYSDAIETLLTAIAVIKQSRVANDER 431
+S SDA LL+AI Q R ++R
Sbjct: 427 KSSLPAVSDARSDLLSAIRQGFQLRRVEEQR 457
Score = 43.1 bits (100), Expect = 6e-04
Identities = 35/110 (31%), Positives = 39/110 (35%), Gaps = 22/110 (20%)
Query: 287 PPPPLSSSFGVPPPPPGIHYQHLMPPPPRL--------------PPHLAVPPPGAIPPAL 332
PPPP S S P P +L PPP P +V P PPA
Sbjct: 247 PPPPQSDS--ASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP 304
Query: 333 HL------NPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVS 376
L P F PPP PPP + P GS + PPPS S
Sbjct: 305 PLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPS 354
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/143 (37%), Positives = 66/143 (46%), Gaps = 27/143 (18%)
Query: 223 VPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPP 282
+P GIPP G P +P A + PP + PP LP +G+PP
Sbjct: 1102 LPGVGIPP-------PPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Query: 283 PP------IPPPPPLSSSFGVPPPPP--GIHYQHLMPPPPRLPPHLAVPPP-----GAIP 329
PP IPPPPPL + G+PPPPP G+ +PPPP LP + +PPP IP
Sbjct: 1154 PPPLPGAGIPPPPPLPGA-GIPPPPPLPGVG----IPPPPPLPG-VGIPPPPPLPGAGIP 1207
Query: 330 PALHLNPAFFPPPNATVGPPPDT 352
P L PP A PPP T
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGT 1230
Score = 68.9 bits (167), Expect = 1e-11
Identities = 56/151 (37%), Positives = 63/151 (41%), Gaps = 26/151 (17%)
Query: 223 VPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPP 282
+P GIPP G A P +P A + PP + PP LP G+PP
Sbjct: 937 LPGAGIPP-------PPPLPGAAIPPPPPLPG-AGIPLPPPLPGAGIPPPPPLPGAGIPP 988
Query: 283 PP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP----GAIPPA 331
PP IPPPPPL + PPP PG +PPPP LP PPP IPP
Sbjct: 989 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPP 1044
Query: 332 LHLNPAFFPPPNATVG---PPPDTYMKASAP 359
L A PPP G PPP A P
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1075
Score = 67.8 bits (164), Expect = 2e-11
Identities = 59/177 (33%), Positives = 70/177 (39%), Gaps = 39/177 (22%)
Query: 223 VPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPP 282
+P GIPP G P +P A + PP + PP LP G+PP
Sbjct: 1047 LPGAGIPP-------PPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPP 1098
Query: 283 PP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPPPPRLP----------PHLAVPPP 325
PP IPPPPPL + PPP PG +PPPP LP P + +PPP
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPLPRVGIPPP 1154
Query: 326 -----GAIPPALHLNPAFFPPPNATVG-----PPPDTYMKASAPYNHHGSRDSGPPP 372
IPP L A PPP G PPP + P G+ PPP
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
Score = 67.4 bits (163), Expect = 3e-11
Identities = 52/143 (36%), Positives = 61/143 (42%), Gaps = 27/143 (18%)
Query: 223 VPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPP 282
+P GIPP G P +P A + PP + PP LP G+PP
Sbjct: 1025 LPGAGIPP-------PPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPP 1076
Query: 283 PP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP----GAIPPA 331
PP IPPPPPL + PPP PG+ +PPPP LP PPP IPP
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVG----IPPPPPLPGAGIPPPPPLPGAGIPPP 1132
Query: 332 LHLNPAFFPP----PNATVGPPP 350
L A PP P + PPP
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPP 1155
Score = 65.5 bits (158), Expect = 1e-10
Identities = 48/114 (42%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 261 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPP 312
PP LP PP LP G+PPPP IPPPPPL + PPP PG +PP
Sbjct: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPP 1043
Query: 313 PPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 359
PP LP PPP IPP L A PPP G PPP A P
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
Score = 62.8 bits (151), Expect = 7e-10
Identities = 47/114 (41%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 261 PPSVLPYFN-RPPSALPLMGLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPP 312
PP LP P LP G+PPPP IPPPPPL + +PPP PG +PP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG----IPP 977
Query: 313 PPRLPPHLAVPPP----GAIPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 359
PP LP PPP IPP L A PPP G PPP A P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1031
Score = 62.4 bits (150), Expect = 1e-09
Identities = 53/155 (34%), Positives = 61/155 (39%), Gaps = 34/155 (21%)
Query: 223 VPRGGIPPRAHSRDSSDSADGRATPSENLVP----SSARVDKPPSVLPYFNRPPSALPLM 278
+P GIPP P ++P A + PP + PP LP
Sbjct: 915 LPGAGIPPPP------------PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
Query: 279 GLPPPP------IPPPPPL-SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP----GA 327
G+P PP IPPPPPL + PPP PG +PPPP LP PPP
Sbjct: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPLPGAG 1018
Query: 328 IPPALHLNPAFFPPPNATVG---PPPDTYMKASAP 359
IPP L A PPP G PPP A P
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1053
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/136 (37%), Positives = 59/136 (43%), Gaps = 17/136 (12%)
Query: 246 TPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIH 305
T S + +P V PP LP P LP IP PPPL + +PPPPP +
Sbjct: 864 TESSSSMPGLGMVPPPPPPLPGMTVPT-------LPSTAIPQPPPLQGTEMLPPPPPPLP 916
Query: 306 YQHLMPPPPRLPPH--LAVPP-PGA-IPPALHLNPAFFPPPNATVG-----PPPDTYMKA 356
+ PPPP LP L +PP PGA IPP L A PPP G PPP
Sbjct: 917 GAGI-PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
Query: 357 SAPYNHHGSRDSGPPP 372
P G+ PPP
Sbjct: 976 PPPPPLPGAGIPPPPP 991
Score = 47.0 bits (110), Expect = 4e-05
Identities = 34/80 (42%), Positives = 40/80 (50%), Gaps = 17/80 (21%)
Query: 261 PPSVLPYFN-RPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMP--PPPRLP 317
PP LP PP LP MG+PP P PP PP + G+PPPP L+P PP LP
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT--GIPPPP-------LLPVSGPPLLP 1247
Query: 318 P--HLAVPPP---GAIPPAL 332
+P P G +PP L
Sbjct: 1248 QVGSSTLPTPQVCGFLPPPL 1267
Score = 45.8 bits (107), Expect = 9e-05
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 27/128 (21%)
Query: 223 VPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPP 282
+P GIPP G P +P + PP + PP LP G
Sbjct: 1157 LPGAGIPP-------PPPLPGAGIPPPPPLPGVG-IPPPPPLPGVGIPPPPPLPGAG--- 1205
Query: 283 PPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP 342
IPPPPPL G+PP P PP PP +PPP +P + P P
Sbjct: 1206 --IPPPPPL-PGMGIPP----------APAPPLPPPGTGIPPPPLLPVS---GPPLLPQV 1249
Query: 343 NATVGPPP 350
++ P P
Sbjct: 1250 GSSTLPTP 1257
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 69.3 bits (168), Expect = 8e-12
Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 15/102 (14%)
Query: 261 PPSVLPYFNRPPSALPLMG----LPPPPIP-------PPPPLSSSFGVPPPPPGIHYQHL 309
PP LP PS L G PPPP+P PPPPL S G+PPPPP + +
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703
Query: 310 MPP-PPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 350
MPP PP LP +PPP P + P PPP + PPP
Sbjct: 704 MPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGMGMPPPP 742
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 242 DGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPP 301
+G PS + +P + PP + PP PL G P PPPPPL G+PPPP
Sbjct: 650 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP-PPPPPLPGEAGMPPPP 708
Query: 302 PGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP 342
P + +PPPP P +PPP PP + + P PPP
Sbjct: 709 PPLPGGPGIPPPPPFPGGPGIPPP---PPGMGMPP---PPP 743
Score = 61.2 bits (147), Expect = 2e-09
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 18/166 (10%)
Query: 196 EKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSS 255
EK D+ Q + ++ E + + A + S + P+ L S
Sbjct: 524 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDS 583
Query: 256 ARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGV--PP---------PPPGI 304
+ PP PP PPPP PPPPPL + PP PPP +
Sbjct: 584 GTIIPPPPAPGDSTTPPP-------PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPL 636
Query: 305 HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 350
+PPPP LP + +P P ++P + P P +A + PPP
Sbjct: 637 SGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682
Score = 59.7 bits (143), Expect = 6e-09
Identities = 45/147 (30%), Positives = 59/147 (40%), Gaps = 38/147 (25%)
Query: 228 IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIP- 286
+PP SR P +P + PP P + P P PPPP+P
Sbjct: 563 VPPSVPSR--------APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPG 614
Query: 287 -----------------PPPPLSSSFGVPPPPP---GIHYQHLMPPPPRLPPHLAVPPPG 326
PPPPLS +PPPPP G+ +P P LP A+PPP
Sbjct: 615 GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG----IPSPSSLPGGTAIPPPP 670
Query: 327 AIPPALHLNPAFFPPP---NATVGPPP 350
+P + + P PPP +A + PPP
Sbjct: 671 PLPGSARIPPP--PPPLPGSAGIPPPP 695
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 17/85 (20%)
Query: 244 RATPSENLVPSSARVDKPPSVLP-YFNRPPSALPLMG---LPPPP-------IPPPPPLS 292
R P +P SA + PP LP PP PL G +PPPP IPPPPP
Sbjct: 677 RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP-- 734
Query: 293 SSFGVPPPPPGIHYQHLMPPPPRLP 317
G+PPPPP + +P P LP
Sbjct: 735 -GMGMPPPPP---FGFGVPAAPVLP 755
Score = 40.0 bits (92), Expect = 0.005
Identities = 37/111 (33%), Positives = 41/111 (36%), Gaps = 38/111 (34%)
Query: 223 VPRG-GIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPY---FNRPPSALP-L 277
+P G GIP S G A P +P SAR+ PP LP PP LP
Sbjct: 648 LPEGVGIP------SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 701
Query: 278 MGLPPPP--------IPPPPPLSS-------------------SFGVPPPP 301
G+PPPP IPPPPP FGVP P
Sbjct: 702 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAP 752
Score = 38.5 bits (88), Expect = 0.015
Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 14/102 (13%)
Query: 277 LMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNP 336
+ L I PP + S VPP PP + PPP P PPP
Sbjct: 553 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP----------- 601
Query: 337 AFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEA 378
PPP PP + S+P + G PPP +A
Sbjct: 602 ---PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 640
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 69.3 bits (168), Expect = 8e-12
Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 15/102 (14%)
Query: 261 PPSVLPYFNRPPSALPLMG----LPPPPIP-------PPPPLSSSFGVPPPPPGIHYQHL 309
PP LP PS L G PPPP+P PPPPL S G+PPPPP + +
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
Query: 310 MPP-PPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 350
MPP PP LP +PPP P + P PPP + PPP
Sbjct: 713 MPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGMGMPPPP 751
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 242 DGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPP 301
+G PS + +P + PP + PP PL G P PPPPPL G+PPPP
Sbjct: 659 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP-PPPPPLPGEAGMPPPP 717
Query: 302 PGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP 342
P + +PPPP P +PPP PP + + P PPP
Sbjct: 718 PPLPGGPGIPPPPPFPGGPGIPPP---PPGMGMPP---PPP 752
Score = 61.2 bits (147), Expect = 2e-09
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 18/166 (10%)
Query: 196 EKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSS 255
EK D+ Q + ++ E + + A + S + P+ L S
Sbjct: 533 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDS 592
Query: 256 ARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGV--PP---------PPPGI 304
+ PP PP PPPP PPPPPL + PP PPP +
Sbjct: 593 GTIIPPPPAPGDSTTPPP-------PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPL 645
Query: 305 HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP 350
+PPPP LP + +P P ++P + P P +A + PPP
Sbjct: 646 SGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691
Score = 59.7 bits (143), Expect = 6e-09
Identities = 45/147 (30%), Positives = 59/147 (40%), Gaps = 38/147 (25%)
Query: 228 IPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIP- 286
+PP SR P +P + PP P + P P PPPP+P
Sbjct: 572 VPPSVPSR--------APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPG 623
Query: 287 -----------------PPPPLSSSFGVPPPPP---GIHYQHLMPPPPRLPPHLAVPPPG 326
PPPPLS +PPPPP G+ +P P LP A+PPP
Sbjct: 624 GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG----IPSPSSLPGGTAIPPPP 679
Query: 327 AIPPALHLNPAFFPPP---NATVGPPP 350
+P + + P PPP +A + PPP
Sbjct: 680 PLPGSARIPPP--PPPLPGSAGIPPPP 704
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 17/85 (20%)
Query: 244 RATPSENLVPSSARVDKPPSVLP-YFNRPPSALPLMG---LPPPP-------IPPPPPLS 292
R P +P SA + PP LP PP PL G +PPPP IPPPPP
Sbjct: 686 RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP-- 743
Query: 293 SSFGVPPPPPGIHYQHLMPPPPRLP 317
G+PPPPP + +P P LP
Sbjct: 744 -GMGMPPPPP---FGFGVPAAPVLP 764
Score = 40.0 bits (92), Expect = 0.005
Identities = 37/111 (33%), Positives = 41/111 (36%), Gaps = 38/111 (34%)
Query: 223 VPRG-GIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPY---FNRPPSALP-L 277
+P G GIP S G A P +P SAR+ PP LP PP LP
Sbjct: 657 LPEGVGIP------SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 710
Query: 278 MGLPPPP--------IPPPPPLSS-------------------SFGVPPPP 301
G+PPPP IPPPPP FGVP P
Sbjct: 711 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAP 761
Score = 38.5 bits (88), Expect = 0.015
Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 14/102 (13%)
Query: 277 LMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNP 336
+ L I PP + S VPP PP + PPP P PPP
Sbjct: 562 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP----------- 610
Query: 337 AFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEA 378
PPP PP + S+P + G PPP +A
Sbjct: 611 ---PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 649
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 67.8 bits (164), Expect = 2e-11
Identities = 59/199 (29%), Positives = 78/199 (39%), Gaps = 26/199 (13%)
Query: 212 EAQARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRP 271
EAQ + RE +V I + +A P P +R PP P N
Sbjct: 243 EAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPP----PPPSRGGPPPPPPPPHNSG 298
Query: 272 PSALPLMGL---PPPPI-------PPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLA 321
P P G PPPP PPPPP S VPPPPP Y PPPP LP
Sbjct: 299 PPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYP---PPPPALPSSAP 355
Query: 322 VPPPGAIPPALHLNPAFFPPPNAT---VGPPPDTYMKASAPYNHHGSRDSGPPPSTVSE- 377
PP P L + P PPP GPPP + + +H +G + + +
Sbjct: 356 SGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDG--DHQVPTTAGNKAALLDQI 413
Query: 378 ---AEFEDIMKRNRAISSS 393
A+ + + + +R +S S
Sbjct: 414 REGAQLKKVEQNSRPVSCS 432
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/80 (42%), Positives = 39/80 (48%), Gaps = 14/80 (17%)
Query: 271 PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPP 330
PP+A PL G+ PPP PP PPL +PPPPP + +PPPP P PPP
Sbjct: 551 PPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPP----- 605
Query: 331 ALHLNPAFFPPPNATVGPPP 350
PPP V PPP
Sbjct: 606 ---------PPPLGGVPPPP 616
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/85 (41%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 279 GLPPPPIPPPPPLSSSFGVPPPPPGIHY---QHLMPPPPRLPPHLAVPPPGAIPPALHLN 335
G+P PP PP P G PPPPP L PPPP LP + +PPP PP L
Sbjct: 547 GIPGPPAAPPLP---GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPP-PPLLFGG 602
Query: 336 PAFFPPPNATVGPPPDTYMKASAPY 360
P PPP G PP + + PY
Sbjct: 603 P---PPPPPLGGVPPPPGISLNLPY 624
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 18/92 (19%)
Query: 251 LVPSSARVDKPPSVLPYFN----RPPSALPLMG---LPPPPIPPPPPLSSSFGVPPPPPG 303
++ SS+ + PP+ P PP A PL G LPPPP PP P + G+PPPPP
Sbjct: 541 VLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP-PPLPGM---MGIPPPPPP 596
Query: 304 IHYQHLMPPPPRLPPHLAVPPPGAIPPALHLN 335
L PP PP VPP PP + LN
Sbjct: 597 ---PLLFGGPPPPPPLGGVPP----PPGISLN 621
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/51 (50%), Positives = 32/51 (62%), Gaps = 9/51 (17%)
Query: 271 PPSALP-LMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHL 320
PP LP +MG+PP PPPPPL FG PPPPP + +PPPP + +L
Sbjct: 580 PPPPLPGMMGIPP---PPPPPL--LFGGPPPPPPLGG---VPPPPGISLNL 622
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/80 (42%), Positives = 39/80 (48%), Gaps = 14/80 (17%)
Query: 271 PPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPP 330
PP+A PL G+ PPP PP PPL +PPPPP + +PPPP P PPP
Sbjct: 551 PPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPP----- 605
Query: 331 ALHLNPAFFPPPNATVGPPP 350
PPP V PPP
Sbjct: 606 ---------PPPLGGVPPPP 616
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/85 (41%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 279 GLPPPPIPPPPPLSSSFGVPPPPPGIHY---QHLMPPPPRLPPHLAVPPPGAIPPALHLN 335
G+P PP PP P G PPPPP L PPPP LP + +PPP PP L
Sbjct: 547 GIPGPPAAPPLP---GVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPP-PPLLFGG 602
Query: 336 PAFFPPPNATVGPPPDTYMKASAPY 360
P PPP G PP + + PY
Sbjct: 603 P---PPPPPLGGVPPPPGISLNLPY 624
Score = 47.8 bits (112), Expect = 2e-05
Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 18/92 (19%)
Query: 251 LVPSSARVDKPPSVLPYFN----RPPSALPLMG---LPPPPIPPPPPLSSSFGVPPPPPG 303
++ SS+ + PP+ P PP A PL G LPPPP PP P + G+PPPPP
Sbjct: 541 VLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP-PPLPGM---MGIPPPPPP 596
Query: 304 IHYQHLMPPPPRLPPHLAVPPPGAIPPALHLN 335
L PP PP VPP PP + LN
Sbjct: 597 ---PLLFGGPPPPPPLGGVPP----PPGISLN 621
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/51 (50%), Positives = 32/51 (62%), Gaps = 9/51 (17%)
Query: 271 PPSALP-LMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHL 320
PP LP +MG+PP PPPPPL FG PPPPP + +PPPP + +L
Sbjct: 580 PPPPLPGMMGIPP---PPPPPL--LFGGPPPPPPLGG---VPPPPGISLNL 622
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/98 (39%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 251 LVPSSARVDKPPSVLPYFNRPPSALPLMGLPP-PPIPPPPPLSSSFGVPPP-------PP 302
+ P +A V P + P PP G PP PP PPPPP F +PPP PP
Sbjct: 662 VTPGAAAVAAPSVLAPTLPLPPPP----GFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPP 717
Query: 303 GIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP 340
H +PPPP LP VPPP +PP P FP
Sbjct: 718 PAHPAVTVPPPP-LPAPPGVPPPPILPPLPPFPPGLFP 754
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/134 (35%), Positives = 55/134 (41%), Gaps = 15/134 (11%)
Query: 226 GGIPPRAHSRDSSDSADGRATP-SENLVPS----SARVDKPPSVLPYFNRPPSALPLMGL 280
G P + D + G S++ +PS SA KP V P A P +
Sbjct: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP--GAAAVAAPSVLA 676
Query: 281 PPPPIPPP---PPLSSSFGVPPPPPGIHYQHLMPPPPRLPP--HLAVPPPGAIPPALHLN 335
P P+PPP PPL PPP PG +PPPP PP H AV P PP L
Sbjct: 677 PTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVP---PPPLPAP 733
Query: 336 PAFFPPPNATVGPP 349
P PPP PP
Sbjct: 734 PGVPPPPILPPLPP 747
Score = 36.2 bits (82), Expect = 0.073
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 10/79 (12%)
Query: 260 KPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPH 319
+PP +LP +PP LP P PP PPP P ++ P PP + P P L
Sbjct: 1269 EPPMMLPLPLQPP--LPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS 1326
Query: 320 LA-------VP-PPGAIPP 330
LA VP PG PP
Sbjct: 1327 LAKSQSTETVPATPGGEPP 1345
Score = 33.9 bits (76), Expect = 0.36
Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 23/102 (22%)
Query: 227 GIPPRAHSRDSSDSAD----GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGL-- 280
G P +A +DS+ A +ATP+ + + P + P P+A G
Sbjct: 365 GPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARD 424
Query: 281 --------PPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPP 314
PPP+PP PL+ P PPG PPPP
Sbjct: 425 SGEFRRAPAPPPLPPAEPLAKE--KPGTPPG-------PPPP 457
Score = 33.1 bits (74), Expect = 0.62
Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 3/71 (4%)
Query: 283 PPIPPPPPLSSSFGVPPPPPGIHYQHLMPP-PPRLPPHLAVPPPGAIPPALHLNPAFFPP 341
PP+ P V P PP + L PP PP PP PPP P + PP
Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPE--PETTDASHPSVPP 1309
Query: 342 PNATVGPPPDT 352
PP T
Sbjct: 1310 EPLAEDHPPHT 1320
Score = 32.0 bits (71), Expect = 1.4
Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 29/98 (29%)
Query: 279 GLPPPPIPPPPPLSSSFGVPPPP------PGIH-----YQHLM---PPPPRLPPHLA--- 321
G PP P S++F PPP PG YQ + PPPP P A
Sbjct: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG 421
Query: 322 ---------VPPPGAIPPALHLNPAFFPPPNATVGPPP 350
P P +PPA P P GPPP
Sbjct: 422 ARDSGEFRRAPAPPPLPPA---EPLAKEKPGTPPGPPP 456
Score = 30.8 bits (68), Expect = 3.1
Identities = 33/119 (27%), Positives = 37/119 (31%), Gaps = 25/119 (21%)
Query: 247 PSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLS-------------- 292
P + P P +V F P LPP P PPPPP
Sbjct: 1510 PGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQ 1569
Query: 293 -SSFGVPPPPPG-----IHYQHLMPP--PPRLPP---HLAVPPPGAIPPALHLNPAFFP 340
S +PP P G Y L P R PP H + PP P P F P
Sbjct: 1570 WPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRP 1628
Score = 29.3 bits (64), Expect = 9.0
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 26/119 (21%)
Query: 239 DSADGRATPSE-NLVPSSARVDKP-PSVLPYFNRPPSA---LPLMGL---PPPPIPPPPP 290
+ AD R P E L A + P P RPP + P L P PP+ P P
Sbjct: 1218 EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP 1277
Query: 291 LSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPP 349
L PP PP P PPR P + PP A H P+ P P A PP
Sbjct: 1278 LQ-----PPLPP--------PRPPRPP---SPPPEPETTDASH--PSVPPEPLAEDHPP 1318
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 64.3 bits (155), Expect = 3e-10
Identities = 45/133 (33%), Positives = 53/133 (39%), Gaps = 23/133 (17%)
Query: 229 PPRAHS--RDSSDSADGRATPSENLVPSSARVDKPPSVLPY----FNRPPSALPLMGLPP 282
PP H + +G A+ + +P PP LP + P P+ PP
Sbjct: 620 PPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPP 679
Query: 283 --PPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP 340
PP PPPPPL PPPP PPPP LP A P PG PPA P
Sbjct: 680 LPPPPPPPPPLPPPSSAGPPPP--------PPPPPLPNSPAPPNPGGPPPAP-------P 724
Query: 341 PPNATVGPPPDTY 353
PP PPP +
Sbjct: 725 PPGLAPPPPPGLF 737
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/146 (33%), Positives = 63/146 (43%), Gaps = 28/146 (19%)
Query: 241 ADGRATPSENLVPSSARVDKPPSVLP---YFNRPPSALPLMG--------LPPPP--IPP 287
++ + T S LVP + + P + + + P+ G LPPPP IPP
Sbjct: 595 SESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPP 654
Query: 288 PPPLSSSFG-VPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATV 346
PPPL S G + P PP MPP PP +PPP PP L + PPP
Sbjct: 655 PPPLPSGLGSLSPAPP-------MPPVSAGPP---LPPPPPPPPPLPPPSSAGPPP---- 700
Query: 347 GPPPDTYMKASAPYNHHGSRDSGPPP 372
PPP + AP N G + PPP
Sbjct: 701 PPPPPPLPNSPAPPNPGGPPPAPPPP 726
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 29/131 (22%)
Query: 215 ARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSA 274
+ +++ + P IPP S G +P+ + P SA PP P PP
Sbjct: 639 SNQQKALPPPPASIPPPP----PLPSGLGSLSPAPPMPPVSAGPPLPPPPPP----PPPL 690
Query: 275 LPLMGLPPPPIPPPPPLSSSFG----------------VPPPPPGIHY-----QHLMPPP 313
P PPP PPPPPL +S PPPPPG+ + P
Sbjct: 691 PPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRK 750
Query: 314 PRLPPHLAVPP 324
P + P + P
Sbjct: 751 PAIEPSCPMKP 761
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 63.9 bits (154), Expect = 3e-10
Identities = 70/254 (27%), Positives = 91/254 (35%), Gaps = 39/254 (15%)
Query: 260 KPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPH 319
KPP P+F PP A P LPPPP PPPP S+ PPPGI + PPP PP
Sbjct: 340 KPP---PFF--PPGAPPTH-LPPPPFLPPPPTVSTAPPLIPPPGI---PITVPPPGFPPP 390
Query: 320 LAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAE 379
PPP IP + + + +A P Y + P+ GS S PS V ++
Sbjct: 391 PGAPPPSLIPTIESGHSSGYDSRSARAFP----YGNVAFPH-LPGSAPSW--PSLVDTSK 443
Query: 380 FEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSL 439
D R + D + R ER R S
Sbjct: 444 QWDYYARREKDRDRERDRDRERDRDRD----------------RERERTRERERERDHSP 487
Query: 440 KDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERN 499
+ + + Y +RHR+ SRE RHR+ H E + R+
Sbjct: 488 TPSVFNSDEERYRYREYAERGYERHRA-------SREKEERHRERRHREKEETRHKSSRS 540
Query: 500 REHERHRDRERDRH 513
RH E D H
Sbjct: 541 NSRRRHESEEGDSH 554
Score = 55.8 bits (133), Expect = 9e-08
Identities = 58/234 (24%), Positives = 85/234 (36%), Gaps = 55/234 (23%)
Query: 291 LSSSFGVPPP--PPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGP 348
+ ++F PPP PPG HL PPPP LPP PP + P PPP +
Sbjct: 334 VDNNFSKPPPFFPPGAPPTHL-PPPPFLPP----------PPTVSTAPPLIPPPGIPITV 382
Query: 349 PPDTYMKASAPYNHHGSRDSGPPPS---TVSEAEFEDIMKRN-RAISSSAISKAVSGASA 404
PP + PPPS T+ R+ RA ++ SA
Sbjct: 383 PPPGFPPP----------PGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSA 432
Query: 405 GDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAKSYSVGASGSSSRKRH 464
+ ++T ++ + + ER R R R
Sbjct: 433 PSWPSLVDTSKQWDYYARREKDRDRERDR------------------------DRERDRD 468
Query: 465 RSRERSPSRSRESSRRHR---DLLHNEDRHDDYFQERNREHERHR-DRERDRHH 514
R RER +R RE R H + ++++ Y + R +ERHR RE++ H
Sbjct: 469 RDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERH 522
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 10/121 (8%)
Query: 243 GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPP 302
G SE P R+ + ++ PP + G PPP + PPPP G PPPPP
Sbjct: 6 GDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRG-PPPLMRPPPPFGMMRG-PPPPP 63
Query: 303 GIHYQHLMPPPPRLPPHLAVPPPGAIPPAL---HL-NPAFFPPPNATVGPPPDTYMKASA 358
+ P P +PP +PPPG IPP + HL P F PPP +++ PPP
Sbjct: 64 RPPFGR-PPFDPNMPP---MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
Query: 359 P 359
P
Sbjct: 120 P 120
Score = 46.6 bits (109), Expect = 5e-05
Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 25/84 (29%)
Query: 261 PPSVLPYFNRPP--SALPLM----GLPPPPIPP--------PPPLSSSFGVPPPPPGIHY 306
PP P F RPP +P M G+PPP PP PPP+SS PPPPG+ +
Sbjct: 60 PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM----PPPPGMMF 115
Query: 307 QHLMPPPPRLPPHLAVPPPGAIPP 330
PP +PP + P A+PP
Sbjct: 116 ------PPGMPP-VTAPGTPALPP 132
Score = 38.5 bits (88), Expect = 0.015
Identities = 67/318 (21%), Positives = 107/318 (33%), Gaps = 62/318 (19%)
Query: 91 STEPPPPVRQEPSPKP------------------NNKTPAILYTYSGLRNRRAAVYVGSF 132
S+ PPPP P P NKTP Y R R +A
Sbjct: 105 SSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESA------ 158
Query: 133 SWWTTDQQLIQVIRSIGVYDVVELKF---AENRANGQSKGYAEVVVASENSVHKLLELLP 189
WT ++VI+ + ++ + A+ +A Q++ A+ ++ +
Sbjct: 159 --WTKPDG-VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
Query: 190 GKVLNGEKVDVRPATRQNLSQFEAQARKRECVRV-----------PRGGIPPRAHSRDSS 238
+ A Q +Q +AQA+ + V+ P P A S +S
Sbjct: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
Query: 239 DSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFG-V 297
S T + S A+ P+ ++ PS+ + P + P P ++ V
Sbjct: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQ---DQTPSSAVSVATPTVSVSTPAPTATPVQTV 332
Query: 298 PPP-----PPGIHYQHLMPP------PPRLPPHLAVPPPGAIPPALHLNPAFFPP----- 341
P P PP + + P PP + P VP PG P + P PP
Sbjct: 333 PQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMI 392
Query: 342 -PNATVGPPPDTYMKASA 358
P + P T A+A
Sbjct: 393 HPQVAIAASPATLAGATA 410
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 10/121 (8%)
Query: 243 GRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPP 302
G SE P R+ + ++ PP + G PPP + PPPP G PPPPP
Sbjct: 6 GDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRG-PPPLMRPPPPFGMMRG-PPPPP 63
Query: 303 GIHYQHLMPPPPRLPPHLAVPPPGAIPPAL---HL-NPAFFPPPNATVGPPPDTYMKASA 358
+ P P +PP +PPPG IPP + HL P F PPP +++ PPP
Sbjct: 64 RPPFGR-PPFDPNMPP---MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM 119
Query: 359 P 359
P
Sbjct: 120 P 120
Score = 46.6 bits (109), Expect = 5e-05
Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 25/84 (29%)
Query: 261 PPSVLPYFNRPP--SALPLM----GLPPPPIPP--------PPPLSSSFGVPPPPPGIHY 306
PP P F RPP +P M G+PPP PP PPP+SS PPPPG+ +
Sbjct: 60 PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM----PPPPGMMF 115
Query: 307 QHLMPPPPRLPPHLAVPPPGAIPP 330
PP +PP + P A+PP
Sbjct: 116 ------PPGMPP-VTAPGTPALPP 132
Score = 30.4 bits (67), Expect = 4.0
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 12/116 (10%)
Query: 245 ATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGI 304
ATP + VP PP+V +P +A+P PP+ PP G+P P PG+
Sbjct: 326 ATPVQT-VPQPHPQTLPPAVPHSVPQPTTAIPAF----PPVMVPPFRVPLPGMPIPLPGV 380
Query: 305 HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP--PPNATVGPPPDTYMKASA 358
++ P +A G +P + P P P + P T A+A
Sbjct: 381 AMMQIVSCP--YVKTVATTKTGVLP---GMAPPIVPMIHPQVAIAASPATLAGATA 431
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 63.2 bits (152), Expect = 6e-10
Identities = 69/249 (27%), Positives = 96/249 (38%), Gaps = 52/249 (20%)
Query: 125 AAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKL 184
A +++G+ ++ L + GV + K + G SKGYA + AS ++
Sbjct: 100 ANIFIGNLDPEIDEKLLYDTFSAFGVI-LQTPKIMRDPDTGNSKGYAFINFASFDASDAA 158
Query: 185 LELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDSADGR 244
+E +NG+ + RP T A +DS G
Sbjct: 159 IE-----AMNGQYLCNRPITVSY------------------------AFKKDSKGERHGS 189
Query: 245 ATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGI 304
A +E L+ + + L +RP L PPP P P+ SS G PPPG
Sbjct: 190 A--AERLLAAQ-------NPLSQADRPHQ---LFADAPPPPSAPNPVVSSLGSGLPPPG- 236
Query: 305 HYQHLMPPPPRLPPHLAVPPPGAIPPAL--HLNPAFFPPPNATVGPPPDTYMKASAPYNH 362
MPPP PP VPPPGA+PP + + P PP A GPP A P +
Sbjct: 237 -----MPPPGSFPP--PVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHG 289
Query: 363 HGSRDSGPP 371
H PP
Sbjct: 290 HSHPHPFPP 298
Score = 53.5 bits (127), Expect = 4e-07
Identities = 32/81 (39%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 270 RPPSALPLMGLPPPPIPPP-PPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAI 328
RPP +P G PP +PP PP S G P P P + PPP +PPH PP
Sbjct: 336 RPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPP---HGMRGPPPLMPPHGYTGPPRPP 392
Query: 329 PPALHLNPAFFPPPNATVGPP 349
P P PPP T PP
Sbjct: 393 PYGYQRGP--LPPPRPTPRPP 411
Score = 52.0 bits (123), Expect = 1e-06
Identities = 32/83 (38%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
Query: 260 KPPSVLPYFNRPPSALPLMGLP-------PPPIPP-----PPPLSSSFGV--PPPPPGIH 305
+PP +P+ PP +P G P P P+PP PPPL G PP PP
Sbjct: 336 RPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYG 395
Query: 306 YQHLMPPPPRLPPHLAVPPPGAI 328
YQ PPPR P VPP G +
Sbjct: 396 YQRGPLPPPRPTPRPPVPPRGPL 418
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 62.8 bits (151), Expect = 7e-10
Identities = 34/81 (41%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Query: 246 TPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIH 305
TPS+ + PP LP P A + LPPPP PPPPP S G PPPPP
Sbjct: 300 TPSQQGIVLGPLAPPPPPPLP----PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPP 355
Query: 306 YQHLMPPPPRLPPHLAVPPPG 326
+ +PPPP PP +P G
Sbjct: 356 LPNQVPPPPPPPPAPPLPASG 376
Score = 55.5 bits (132), Expect = 1e-07
Identities = 74/317 (23%), Positives = 122/317 (38%), Gaps = 33/317 (10%)
Query: 205 RQNLSQFEAQARKRECV-RVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPS 263
R+ L + E + ++RE ++ R + R SS +A N V + +P
Sbjct: 232 RERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG- 290
Query: 264 VLPYFNRPPSALPLMGL------PPPPIP-PPPPLSSSFGVPPPPPGIHYQHLMPPPPRL 316
L ++P G+ PPPP P PP P +S +PPPP PPPP
Sbjct: 291 -LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPG--------PPPPPP 341
Query: 317 PPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKA----SAPYNHHGSRDSGPPP 372
P PPP PP + P PPP A P ++ + + P + +G
Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKL 401
Query: 373 STVSEAEFEDIMKRNRAIS-SSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDER 431
VS E AI +SA SK +G G L+ ++ + R E+
Sbjct: 402 RKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEK 461
Query: 432 CRVLISSLKDCLHGIEAKSYSVGASGSSS---------RKRHRSRERSPSRSRESSRRHR 482
+ + K+ G +++ + AS +S+ R + +SP SR S R
Sbjct: 462 GSTIETEQKED-KGEDSEPVTSKASSTSTPEPTRKPWERTNTMNGSKSPVISRRDSPRKN 520
Query: 483 DLLHNEDRHDDYFQERN 499
++ + +D + ++
Sbjct: 521 QIVFDNRSYDSLHRPKS 537
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 62.8 bits (151), Expect = 7e-10
Identities = 34/81 (41%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Query: 246 TPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIH 305
TPS+ + PP LP P A + LPPPP PPPPP S G PPPPP
Sbjct: 300 TPSQQGIVLGPLAPPPPPPLP----PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPP 355
Query: 306 YQHLMPPPPRLPPHLAVPPPG 326
+ +PPPP PP +P G
Sbjct: 356 LPNQVPPPPPPPPAPPLPASG 376
Score = 53.1 bits (126), Expect = 6e-07
Identities = 51/174 (29%), Positives = 71/174 (40%), Gaps = 25/174 (14%)
Query: 205 RQNLSQFEAQARKRECV-RVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPS 263
R+ L + E + ++RE ++ R + R SS +A N V + +P
Sbjct: 232 RERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG- 290
Query: 264 VLPYFNRPPSALPLMGL------PPPPIP-PPPPLSSSFGVPPPPPGIHYQHLMPPPPRL 316
L ++P G+ PPPP P PP P +S +PPPP PPPP
Sbjct: 291 -LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPG--------PPPPPP 341
Query: 317 PPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGP 370
P PPP PP + P PPP PPP + AS + S D+ P
Sbjct: 342 LPSTGPPPPPPPPPLPNQVPP--PPP-----PPPAPPLPASGFFLASMSEDNRP 388
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/121 (38%), Positives = 56/121 (46%), Gaps = 30/121 (24%)
Query: 224 PRGGIPPRAHSRD---SSDSADGRATPSENLVPS-SARVDKPPSVLPYFNRPPSALPLMG 279
P G+P + S D +++ A G A P +P + + PPS PP A PL G
Sbjct: 517 PTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSA------PPQAPPLPG 570
Query: 280 LPPPP--------IPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPA 331
P PP +PPPPP PPPPPG +PPPP PP PPPG P A
Sbjct: 571 SPEPPPAPPLPGDLPPPPP------PPPPPPGT--DGPVPPPPPPPP----PPPGGPPDA 618
Query: 332 L 332
L
Sbjct: 619 L 619
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/140 (34%), Positives = 54/140 (38%), Gaps = 14/140 (10%)
Query: 235 RDSSDSADGRATPSENLVPSSARVDKP--PSVLPYFNRPPSALPLMGLPPPPIPPPPPLS 292
R D+ P PS P P+ P + P+A P G PPP PP P L
Sbjct: 493 RGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLP 552
Query: 293 SSFGVPP--PP--PGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGP 348
S PP PP P + PP P LP L PPP PP P PPP P
Sbjct: 553 SPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPV--PPPPPPPPP 610
Query: 349 PPDTYMKASAPYNHHGSRDS 368
PP P + G RDS
Sbjct: 611 PP------GGPPDALGRRDS 624
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/134 (34%), Positives = 55/134 (41%), Gaps = 13/134 (9%)
Query: 224 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 283
P+ +PP R SSD++ ATP + + PP PP L LPPP
Sbjct: 512 PKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPP 571
Query: 284 P---IPPPPPLSSSFGVPPPPP---GIHYQHLMPPPPRLPPHLAVPPPGAI--PPALHLN 335
P + PPP VPPPPP GI L PPPP P P P + PPA+
Sbjct: 572 PPDFMEPPPDF-----VPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKR 626
Query: 336 PAFFPPPNATVGPP 349
P P G P
Sbjct: 627 PPVPPKRQENPGHP 640
Score = 49.3 bits (116), Expect = 8e-06
Identities = 50/162 (30%), Positives = 64/162 (39%), Gaps = 36/162 (22%)
Query: 224 PRGGIPPRAHSRDSS-DSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPP 282
P G IP HS + A A S++ P+ P+V + P S+LP PP
Sbjct: 465 PNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGN-HHDPAVPRAPHAPKSSLP----PP 519
Query: 283 PPI--------PPPPPLSSSF----GVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPP 330
PP+ P PL + G+P PP +PPPP PP + P PP
Sbjct: 520 PPVRRSSDTSGSPATPLKAKGTGGGGLPAPP-----DDFLPPPPPPPP---LDDPELPPP 571
Query: 331 ALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPP 372
P F PP V PPP +Y + GS PPP
Sbjct: 572 P----PDFMEPPPDFVPPPPPSYAGIA------GSELPPPPP 603
Score = 30.4 bits (67), Expect = 4.0
Identities = 14/22 (63%), Positives = 16/22 (72%), Gaps = 1/22 (4%)
Query: 271 PPSALPLMGLPPPPIPPPPPLS 292
PP A P++ LP PP PPP PLS
Sbjct: 130 PPPADPVLDLPLPP-PPPEPLS 150
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 60.5 bits (145), Expect = 4e-09
Identities = 56/168 (33%), Positives = 71/168 (42%), Gaps = 17/168 (10%)
Query: 240 SADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP----PIPPPPPLSSSF 295
S G P +V + P +P PP P G PPP P PPPPP +
Sbjct: 320 SRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTP-RGPPPPGRGGPPPPPPPATGRS 378
Query: 296 G-VPPPPPGIHYQHLMPPPPRLPPHLAV---PPPGAIPPALHLNPAFFPPPNATVGPPPD 351
G +PPPPPG + PPPP PP + P P +PPA L PA P G D
Sbjct: 379 GPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA--LVPAGGLAPGGGRGALLD 436
Query: 352 TYMKASAPYNHHGSRDSG---PPPST---VSEAEFEDIMKRNRAISSS 393
+ G+ +S PPP + + A + KR+RAI SS
Sbjct: 437 QIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSS 484
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/96 (35%), Positives = 39/96 (40%), Gaps = 6/96 (6%)
Query: 284 PIPPPPPLSSSFGVPPPPP--GIHYQHLMPPPPRLPPHLAVPPP---GAIPPALHLNPAF 338
P+PPPPP S P PP G + P PP +P +A PPP G PP P
Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPP-VPLGIAPPPPTPRGPPPPGRGGPPPP 370
Query: 339 FPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPST 374
PP GP P A P PPPS+
Sbjct: 371 PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSS 406
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/238 (25%), Positives = 96/238 (40%), Gaps = 48/238 (20%)
Query: 165 GQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVP 224
G G A +V A++ +L + G + G KV + +++ + +R+R
Sbjct: 37 GGELGEAFIVFATDEDA-RLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRR--FETA 93
Query: 225 RGGIPPRAHSRDSSDSADGRAT-------------PSENLVPSSARVDK----------- 260
IPP SR + G ++ PS ++V ++ V +
Sbjct: 94 NLDIPPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTA 153
Query: 261 -----PPSVLPYFNRPP-------SALPLMGLPPPPIPPPPPLSSSFGVP-----PPPPG 303
PP++ F P +A P+ +PPPPIPP P + S +P P PP
Sbjct: 154 SVGTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPP 213
Query: 304 IHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYN 361
+ +PP P +PP +VPP +PP + P PPP V P P + AP N
Sbjct: 214 VPTLPPVPPVPPIPPVPSVPPMTPLPPMSGM-PPLNPPP---VAPLPAGMNGSGAPMN 267
Score = 42.0 bits (97), Expect = 0.001
Identities = 70/292 (23%), Positives = 109/292 (37%), Gaps = 46/292 (15%)
Query: 113 ILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAE 172
IL + + + ++ + + T ++Q + I V + +N NGQ G A
Sbjct: 532 ILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDN--NGQGLGQAL 589
Query: 173 VVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQ--ARKRECVRVPRGGIPP 230
V +E+ K E L K LNG + V T +++ + E A+ ++ +++P G P
Sbjct: 590 VQFKNEDDARKS-ERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNP- 647
Query: 231 RAHSRDSSDSADGRATPSENL----VPSSARVDKPPSVLPYFNRPPSALPLMGLPP---- 282
A + G PS L +PS+ P S + P + +P G+P
Sbjct: 648 -AVPGMPNAGLPGVGLPSAGLPGAGLPSTGL---PGSAITSAGLPGAGMPSAGIPSAGGE 703
Query: 283 ---------------PPIPPPPPL--SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP 325
PP P S++FG P PPPG+ P +P +V
Sbjct: 704 EHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMP---SVGNS 760
Query: 326 GAIPPALHLN-PAFFPPPNATVGPP-----PDTYMKASAPYNHHGSRDSGPP 371
G P L L+ P F PN GP P + SGPP
Sbjct: 761 GL--PGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPP 810
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/238 (25%), Positives = 96/238 (40%), Gaps = 48/238 (20%)
Query: 165 GQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVP 224
G G A +V A++ +L + G + G KV + +++ + +R+R
Sbjct: 37 GGELGEAFIVFATDEDA-RLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRR--FETA 93
Query: 225 RGGIPPRAHSRDSSDSADGRAT-------------PSENLVPSSARVDK----------- 260
IPP SR + G ++ PS ++V ++ V +
Sbjct: 94 NLDIPPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTA 153
Query: 261 -----PPSVLPYFNRPP-------SALPLMGLPPPPIPPPPPLSSSFGVP-----PPPPG 303
PP++ F P +A P+ +PPPPIPP P + S +P P PP
Sbjct: 154 SVGTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPP 213
Query: 304 IHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYN 361
+ +PP P +PP +VPP +PP + P PPP V P P + AP N
Sbjct: 214 VPTLPPVPPVPPIPPVPSVPPMTPLPPMSGM-PPLNPPP---VAPLPAGMNGSGAPMN 267
Score = 42.0 bits (97), Expect = 0.001
Identities = 70/292 (23%), Positives = 109/292 (37%), Gaps = 46/292 (15%)
Query: 113 ILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAE 172
IL + + + ++ + + T ++Q + I V + +N NGQ G A
Sbjct: 532 ILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDN--NGQGLGQAL 589
Query: 173 VVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQ--ARKRECVRVPRGGIPP 230
V +E+ K E L K LNG + V T +++ + E A+ ++ +++P G P
Sbjct: 590 VQFKNEDDARKS-ERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNP- 647
Query: 231 RAHSRDSSDSADGRATPSENL----VPSSARVDKPPSVLPYFNRPPSALPLMGLPP---- 282
A + G PS L +PS+ P S + P + +P G+P
Sbjct: 648 -AVPGMPNAGLPGVGLPSAGLPGAGLPSTGL---PGSAITSAGLPGAGMPSAGIPSAGGE 703
Query: 283 ---------------PPIPPPPPL--SSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP 325
PP P S++FG P PPPG+ P +P +V
Sbjct: 704 EHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMP---SVGNS 760
Query: 326 GAIPPALHLN-PAFFPPPNATVGPP-----PDTYMKASAPYNHHGSRDSGPP 371
G P L L+ P F PN GP P + SGPP
Sbjct: 761 GL--PGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPP 810
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 60.1 bits (144), Expect = 5e-09
Identities = 50/163 (30%), Positives = 64/163 (39%), Gaps = 20/163 (12%)
Query: 234 SRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLM---GLP-PPPIP--- 286
S D DS E++ + + +D PP P P PL +P PPP+P
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
Query: 287 -------PPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFF 339
P PPL P PPP Q PPPP PP A+P P PP + P+
Sbjct: 1441 SANSNGTPEPPLLEEKPPPTPPPAPTPQP-QPPPPPPPPQPALPSP---PPLVAPTPSSP 1496
Query: 340 PPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFED 382
PPP + PPP M + P + PP + ED
Sbjct: 1497 PPP--PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/130 (33%), Positives = 52/130 (40%), Gaps = 16/130 (12%)
Query: 229 PPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVL-------PYFNRPPSALPLMGLP 281
PP A +D+S + DG VP + PS P P P
Sbjct: 1408 PPLAGPKDTS-TPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466
Query: 282 PPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPP 341
P P PPPPP +P PPP + PPPP LPP PPP A+P P PP
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP----PPPPAMPSP----PPPPPP 1518
Query: 342 PNATVGPPPD 351
A + PP+
Sbjct: 1519 AAAPLAAPPE 1528
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/103 (31%), Positives = 41/103 (39%), Gaps = 17/103 (16%)
Query: 287 PPPPLSSSFGVPPPPPGIHYQH--------LMPPPPRLPP----HLAVPPPGAIPPALH- 333
PPPP ++ P P G+ + L PPPP+L P H P P A +H
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 334 LNPAFF----PPPNATVGPPPDTYMKASAPYNHHGSRDSGPPP 372
L PA PP PPP ++ A HG + P P
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
Score = 42.0 bits (97), Expect = 0.001
Identities = 49/177 (27%), Positives = 66/177 (37%), Gaps = 42/177 (23%)
Query: 275 LPLMGLPPPPI----------PPPPPLSSSFGV------------------PPPPPGIHY 306
LPL+ LPPPP P P P +S GV PPPPP +
Sbjct: 790 LPLV-LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848
Query: 307 Q---HL-------MPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNAT-VGPPPDTYMK 355
Q HL P PRL P ++ PPGA+ L P P T VGPP
Sbjct: 849 QLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKD 908
Query: 356 ASAPYNHHGSRDSGPPPST-VSEAEFEDIMKRNRAIS-SSAISKAVSGASAGDYSDA 410
+ Y + + P ++ F D + ++ S + + G +A DY A
Sbjct: 909 PAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKA 965
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 5/73 (6%)
Query: 253 PSSARVDKPPSVLPYFNRPPSALPLMGLPPPPI----PPPPPLSSSFGVPPPPPGIHYQH 308
P A PP V P + PP PL PPP + PPPPP ++ PP P
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPP-PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE 1536
Query: 309 LMPPPPRLPPHLA 321
P P HLA
Sbjct: 1537 DPELPDTRPLHLA 1549
Score = 35.8 bits (81), Expect = 0.096
Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 9/55 (16%)
Query: 240 SADGRATPSENLVPSSARVDKPPSVLPYFNRPPSAL----PLMGLPPPPIPPPPP 290
S G TP L P+ KPP + N P L P PPPP PPPPP
Sbjct: 999 SGAGPETPGLGLDPN-----KPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPP 1048
Score = 30.8 bits (68), Expect = 3.1
Identities = 43/176 (24%), Positives = 54/176 (30%), Gaps = 54/176 (30%)
Query: 245 ATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPP---------------- 288
A P + PSS+ + + +RP + L PP PP
Sbjct: 135 ALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPS 194
Query: 289 --PPLSSSFG-------------------VPPPPPGIHYQHLMPPPPRLPP---HLAVPP 324
P + SS G PP PG PPPPR P +L
Sbjct: 195 QAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPG---PPDPPPPPRHLPTQFNLLASS 251
Query: 325 PGAIPPALHLNPAFFPPPNATVGPPP--------DTYMKASAPYNHHGSRDSGPPP 372
A A +P + A GPPP DT +K Y S PPP
Sbjct: 252 SAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIK---HYQRPASAQPPPPP 304
Score = 30.4 bits (67), Expect = 4.0
Identities = 27/87 (31%), Positives = 29/87 (33%), Gaps = 31/87 (35%)
Query: 276 PLMGLPPPPIPP------PPPLSSSFGVPPPPPGIHYQHLMPPPPRLP------------ 317
P G PPP PP P + G P PG+ PP LP
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDP--NKPPELPSTVNAEPLGLIQ 1031
Query: 318 --PHLAVPPPGAIPPALHLNPAFFPPP 342
PH A PPP PP PPP
Sbjct: 1032 SGPHQAAPPPPPPPP---------PPP 1049
Score = 30.0 bits (66), Expect = 5.3
Identities = 28/105 (26%), Positives = 36/105 (34%), Gaps = 26/105 (24%)
Query: 281 PPPPIPPPPP--LSSSFGV------------PPPPPGIHYQHLMPPPPRLPPHLAVPPPG 326
P PP PPPPP L + F + P ++ P PP PP A+P
Sbjct: 229 PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP--PPERALPRQD 286
Query: 327 AIPPALHLNPAFFPPPNATVGPPPDT-----YMKASAPYNHHGSR 366
+ + PPP PPP Y+ Y G R
Sbjct: 287 TVIKHYQRPASAQPPP-----PPPPAHALQHYLSCGGSYPSMGHR 326
Score = 29.6 bits (65), Expect = 6.9
Identities = 17/39 (43%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 289 PPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGA 327
PPLS VPP P + L P PP P PP GA
Sbjct: 1305 PPLSPPKSVPPSVPA---RGLQPQPPATPAVPHPPPSGA 1340
Score = 29.6 bits (65), Expect = 6.9
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 9/71 (12%)
Query: 268 FNRPPSALPLMGLPPPPIPP-----PPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAV 322
++RPP + G P+ PPP + + PPP P + PP P A+
Sbjct: 1667 WHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPA---PPPKPETPEKTTSEKPPEQTPETAM 1723
Query: 323 P-PPGAIPPAL 332
P PP P+L
Sbjct: 1724 PEPPAPEKPSL 1734
Score = 29.3 bits (64), Expect = 9.0
Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 5/77 (6%)
Query: 218 RECVRVP--RGGIPPRAHSRDSSD-SADGRATPSENLVPSSARVDKPPSVLPYFNRPPSA 274
R C R P R +P R + + SA G + P + + P +PP
Sbjct: 1660 RVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTS--EKPPEQ 1717
Query: 275 LPLMGLPPPPIPPPPPL 291
P +P PP P P L
Sbjct: 1718 TPETAMPEPPAPEKPSL 1734
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 59.7 bits (143), Expect = 6e-09
Identities = 42/118 (35%), Positives = 50/118 (42%), Gaps = 19/118 (16%)
Query: 260 KPPSVLPYFNRPPSALPLMGLPPPPIPPPPP----LSSSFGVPPPPPGIHYQHLMPPPPR 315
+PPS +RPPS PL PPP PP P + + GVPPP PP P
Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861
Query: 316 LPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPS 373
L P + PP G +PPA HL PP + A A + SR P PS
Sbjct: 862 LRPQ-SQPPEGPLPPAPHL--------------PPSSTSSAVASSSETSSRLPAPTPS 904
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 22/130 (16%)
Query: 224 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPP 283
P G +PP H SS S+ A+ SE +S+R+ P PPS P PP
Sbjct: 869 PEGPLPPAPHLPPSSTSS-AVASSSE----TSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
Query: 284 P----IPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFF 339
P +P P PPPPP +Q + P P A+P P A+ H P+
Sbjct: 924 PTLHLVPEP-------AAPPPPPPRTFQMVTTPFP------ALPQPKALLERFHQVPSGI 970
Query: 340 PPPNATVGPP 349
N G P
Sbjct: 971 ILQNKAGGAP 980
Score = 35.4 bits (80), Expect = 0.13
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 4/51 (7%)
Query: 271 PPSALPLMGLPPPPIPPPPPLSSSFG-VPPPPPGIHYQHLM---PPPPRLP 317
PP+ L + PP P PPPPP G V PPP + + P PRLP
Sbjct: 1336 PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLP 1386
Score = 34.7 bits (78), Expect = 0.21
Identities = 37/119 (31%), Positives = 40/119 (33%), Gaps = 29/119 (24%)
Query: 266 PYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPP 325
P PP L PPP PPP PPPP G + PPP P P
Sbjct: 1329 PVHQPPPPPATLKVAEPPPRPPP---------PPPPTGQMNGTVDHPPPAAPER---KPL 1376
Query: 326 GAIP--PALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSG----PPPSTVSEA 378
G P P L L + VG P AP R G P P+ V EA
Sbjct: 1377 GTAPHCPRLPLRKTY----RENVGGP-------GAPEGTPAGRARGGSPAPLPAKVDEA 1424
Score = 34.3 bits (77), Expect = 0.28
Identities = 27/116 (23%), Positives = 42/116 (36%), Gaps = 7/116 (6%)
Query: 263 SVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAV 322
+VL PPSA+ ++ P + P P +++ P + P P+ PP ++
Sbjct: 581 TVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLT-------VQPAPQAPPAVST 633
Query: 323 PPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEA 378
P P + P P P A P T + + G PPS A
Sbjct: 634 PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTA 689
Score = 33.1 bits (74), Expect = 0.62
Identities = 45/192 (23%), Positives = 67/192 (34%), Gaps = 39/192 (20%)
Query: 212 EAQARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKPPSVL------ 265
+ QA++ P+ PP+A + S G A+ E +V P ++L
Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSP---GLASSPEKIVLGQPPSATPTAILTQDSLQ 697
Query: 266 ----------------PYFNRPPSALPLMGLPPPPIPPPP--PLSSSFGVPPPPPGIHYQ 307
P+ + P S + + PPP P P P++ G+ P P Q
Sbjct: 698 MFLPQERSQQPLSAEGPHLSVPASVI--VSAPPPAQDPAPATPVAKGAGLGPQAP--DSQ 753
Query: 308 HLMPPPPRLP--PHLAVPPPGAIPPALHLNP----AFFPPPNATVGP--PPDTYMKASAP 359
P P++P L P P + P H P P P+ T P PP S P
Sbjct: 754 ASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRP 813
Query: 360 YNHHGSRDSGPP 371
+ PP
Sbjct: 814 PSEPPLHPCPPP 825
Score = 29.6 bits (65), Expect = 6.9
Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 14/120 (11%)
Query: 224 PRGGIPPRAHSRDSSDSADGRATPSENLVPSSA-RVDKPPSVLPYF--NRPPSALPLMGL 280
P G +PP+ + A AT + P + + K P L + + + L G
Sbjct: 355 PAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGF 414
Query: 281 PPPPIPP----PPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNP 336
P P + PP +++ PP PPG L P + HL + PA H+ P
Sbjct: 415 PAPALQANVFKQPPATTTGAAPPQPPGA----LSKP---MSVHLLNQGSSIVIPAQHMLP 467
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
sapiens]
Length = 1792
Score = 59.3 bits (142), Expect = 8e-09
Identities = 64/246 (26%), Positives = 93/246 (37%), Gaps = 44/246 (17%)
Query: 272 PSALPLMGLPPPPIPPPPP--LSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIP 329
P+ + +PPPP+ PPPP L GVPPP + PP P +VPPPG
Sbjct: 551 PATPVFVPVPPPPLYPPPPHTLPLPPGVPPP----QFSPQFPPGQPPPAGYSVPPPG--- 603
Query: 330 PALHLNPAFFPPPNATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMKRNRA 389
FPP A + P ++ + H + P + E+ + R
Sbjct: 604 ---------FPPAPANLSTP---WVSSGVQTAHSNT----IPTTQAPPLSREEFYREQRR 647
Query: 390 ISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISSLKDCLHGIEAK 449
+ K+ D++ L I++ R + R + S + +
Sbjct: 648 LKEEEKKKSKLDEFTNDFAKE----LMEYKKIQKERRRSFSRSK---SPYSGSSYSRSSY 700
Query: 450 SYSVGASGSS-----SRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNREHER 504
+YS SGS+ SR RS RS SRS RR R N ++ R+R H
Sbjct: 701 TYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRN-------YRSRSRSHGY 753
Query: 505 HRDRER 510
HR R R
Sbjct: 754 HRSRSR 759
Score = 34.7 bits (78), Expect = 0.21
Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 6/93 (6%)
Query: 281 PPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFP 340
PPPPIPPP PL P I Q P +P + P +L N +
Sbjct: 339 PPPPIPPPRPLIQRNLQPLMRSPISRQQ---DPLMIPVTSSSTHPAPSISSLTSNQSSLA 395
Query: 341 PP---NATVGPPPDTYMKASAPYNHHGSRDSGP 370
PP N + P P + A+ + H + GP
Sbjct: 396 PPVSGNPSSAPAPVPDITATVSISVHSEKSDGP 428
Score = 34.7 bits (78), Expect = 0.21
Identities = 37/168 (22%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Query: 359 PYNHHGSRDSGPPPSTVSEAEFE-DIMKRNRAISSSAISKAVSGASAGDYSDAI-----E 412
P H SR S EA FE D + + + S + SG + D D I E
Sbjct: 1616 PQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKE 1675
Query: 413 TLLTAIAVIKQSRVANDERCRVLIS-SLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSP 471
+L TA AV++ N +S S G + +S+S AS + S+ + +++
Sbjct: 1676 SLDTA-AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKE 1734
Query: 472 SRSRESSRRHRDLLHNEDRHDDYFQERNREH-------ERHRDRERDR 512
+ + ++H+ H + + E++++H ++++D+E+++
Sbjct: 1735 KKKHKKHKKHKK--HKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEK 1780
Score = 30.4 bits (67), Expect = 4.0
Identities = 16/62 (25%), Positives = 29/62 (46%), Gaps = 4/62 (6%)
Query: 457 GSSSRKRHRSRERSPSRSRESS----RRHRDLLHNEDRHDDYFQERNREHERHRDRERDR 512
G S + H S SPSRS S R H + + D +++ +E ++H+ ++ +
Sbjct: 1686 GISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHK 1745
Query: 513 HH 514
H
Sbjct: 1746 KH 1747
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 58.9 bits (141), Expect = 1e-08
Identities = 37/88 (42%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 272 PSALPLMGLPPPPIPPPPPLSSSFGVPPPPP--------GIHYQHLMPPPPRLPPHLAVP 323
P AL PPP PPPP L S PPPPP G PPPP LP A+
Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA 470
Query: 324 PPG-AIPPALHLNPAFFPPPNATVGPPP 350
PP +PP L + F PPP PPP
Sbjct: 471 PPAPPLPPPLPGSCEFLPPP-----PPP 493
Score = 57.8 bits (138), Expect = 2e-08
Identities = 39/93 (41%), Positives = 41/93 (44%), Gaps = 15/93 (16%)
Query: 271 PPSALPLMGLPPPPIPPPPPLSSSFG-----VPPPPPGIHYQHLMPPPPRLPPHLA---- 321
PP LP PPP PPPPPL S PPPPP + PP P LPP L
Sbjct: 426 PPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCE 485
Query: 322 -VPPPGAIPPALHLNPAFFPP---PNATVGPPP 350
+PPP P L P PP P GPPP
Sbjct: 486 FLPPPPPPLPGLGCPPP--PPPLLPGMGWGPPP 516
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/111 (36%), Positives = 48/111 (43%), Gaps = 17/111 (15%)
Query: 247 PSENLVPSSARVDKPPSVLPYFNR----------PPSALPLMGL---PPPPIPPPPPLSS 293
P L+P S+ PP P PP LP +G P PP+PPP P S
Sbjct: 425 PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSC 484
Query: 294 SFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNA 344
F +PPPPP + PPPP L P + PP PP L P PP A
Sbjct: 485 EF-LPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLL---PCTCSPPVA 531
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 25/109 (22%)
Query: 261 PPSVLPYFNRPPSALPLMGLPPPPIP----------PPPPLSSSFG--------VPPPPP 302
PP +LP + P P PPPP+P PPPP G +PPP P
Sbjct: 426 PPPLLPGSSAEPPPPP----PPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLP 481
Query: 303 GIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP--NATVGPP 349
G + L PPPP LP PPP + P + P PPP T PP
Sbjct: 482 G-SCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPP 529
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/107 (35%), Positives = 46/107 (42%), Gaps = 23/107 (21%)
Query: 261 PPSVLPYFNR-----PPSALPLMG----LPPPPIPPPPPLSSSFGVPPPP----PGIHYQ 307
PP LP PP PL G LPPPP PP P L G PPPP PG+ +
Sbjct: 459 PPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPP-PPLPGL----GCPPPPPPLLPGMGWG 513
Query: 308 HLMPPPPRLPPHLAVPPPGAIPPAL-----HLNPAFFPPPNATVGPP 349
PPPP LP + P G + + H + + P + V PP
Sbjct: 514 PPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGSAWVPSHRRVNPP 560
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 58.9 bits (141), Expect = 1e-08
Identities = 37/88 (42%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 272 PSALPLMGLPPPPIPPPPPLSSSFGVPPPPP--------GIHYQHLMPPPPRLPPHLAVP 323
P AL PPP PPPP L S PPPPP G PPPP LP A+
Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA 470
Query: 324 PPG-AIPPALHLNPAFFPPPNATVGPPP 350
PP +PP L + F PPP PPP
Sbjct: 471 PPAPPLPPPLPGSCEFLPPP-----PPP 493
Score = 57.8 bits (138), Expect = 2e-08
Identities = 39/93 (41%), Positives = 41/93 (44%), Gaps = 15/93 (16%)
Query: 271 PPSALPLMGLPPPPIPPPPPLSSSFG-----VPPPPPGIHYQHLMPPPPRLPPHLA---- 321
PP LP PPP PPPPPL S PPPPP + PP P LPP L
Sbjct: 426 PPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCE 485
Query: 322 -VPPPGAIPPALHLNPAFFPP---PNATVGPPP 350
+PPP P L P PP P GPPP
Sbjct: 486 FLPPPPPPLPGLGCPPP--PPPLLPGMGWGPPP 516
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/111 (36%), Positives = 48/111 (43%), Gaps = 17/111 (15%)
Query: 247 PSENLVPSSARVDKPPSVLPYFNR----------PPSALPLMGL---PPPPIPPPPPLSS 293
P L+P S+ PP P PP LP +G P PP+PPP P S
Sbjct: 425 PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSC 484
Query: 294 SFGVPPPPPGIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNA 344
F +PPPPP + PPPP L P + PP PP L P PP A
Sbjct: 485 EF-LPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLL---PCTCSPPVA 531
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 25/109 (22%)
Query: 261 PPSVLPYFNRPPSALPLMGLPPPPIP----------PPPPLSSSFG--------VPPPPP 302
PP +LP + P P PPPP+P PPPP G +PPP P
Sbjct: 426 PPPLLPGSSAEPPPPP----PPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLP 481
Query: 303 GIHYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP--NATVGPP 349
G + L PPPP LP PPP + P + P PPP T PP
Sbjct: 482 G-SCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPP 529
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/107 (35%), Positives = 46/107 (42%), Gaps = 23/107 (21%)
Query: 261 PPSVLPYFNR-----PPSALPLMG----LPPPPIPPPPPLSSSFGVPPPP----PGIHYQ 307
PP LP PP PL G LPPPP PP P L G PPPP PG+ +
Sbjct: 459 PPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPP-PPLPGL----GCPPPPPPLLPGMGWG 513
Query: 308 HLMPPPPRLPPHLAVPPPGAIPPAL-----HLNPAFFPPPNATVGPP 349
PPPP LP + P G + + H + + P + V PP
Sbjct: 514 PPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGSAWVPSHRRVNPP 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,943,802
Number of Sequences: 37866
Number of extensions: 2069209
Number of successful extensions: 34558
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 674
Number of HSP's successfully gapped in prelim test: 1231
Number of HSP's that attempted gapping in prelim test: 11813
Number of HSP's gapped (non-prelim): 10744
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.