Search of human proteins with 215490011

Search of human proteins with 215490011

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215490011 small inducible cytokine subfamily E, member 1
isoform b precursor [Homo sapiens]
         (336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215490011 small inducible cytokine subfamily E, member 1 isof...   656   0.0  
gi|215490009 small inducible cytokine subfamily E, member 1 isof...   611   e-175
gi|45006986 small inducible cytokine subfamily E, member 1 isofo...   611   e-175
gi|4507947 tyrosyl-tRNA synthetase [Homo sapiens]                     170   2e-42
gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]                40   0.002
gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]                40   0.002
gi|116008447 CAP-GLY domain containing linker protein 2 isoform ...    40   0.003
gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2...    40   0.003
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    40   0.003
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             40   0.004
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             40   0.004
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             40   0.004
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    39   0.005
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    39   0.005
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    39   0.007
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    39   0.007
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    39   0.007
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     39   0.009
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    38   0.011
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    38   0.011
gi|71061468 centromere protein E [Homo sapiens]                        38   0.011
gi|16262452 cingulin [Homo sapiens]                                    38   0.015
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 37   0.019
gi|4505257 moesin [Homo sapiens]                                       37   0.025
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      37   0.033
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                37   0.033
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       37   0.033
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ...    36   0.043
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    36   0.043
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan...    36   0.043

>gi|215490011 small inducible cytokine subfamily E, member 1 isoform
           b precursor [Homo sapiens]
          Length = 336

 Score =  656 bits (1693), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA 60
           MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
Sbjct: 1   MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA 60

Query: 61  ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV 120
           ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
Sbjct: 61  ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV 120

Query: 121 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD 180
           IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
Sbjct: 121 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD 180

Query: 181 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA 240
           LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
Sbjct: 181 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA 240

Query: 241 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP 300
           KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
Sbjct: 241 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP 300

Query: 301 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK 336
           DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
Sbjct: 301 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK 336


>gi|215490009 small inducible cytokine subfamily E, member 1 isoform
           a precursor [Homo sapiens]
          Length = 312

 Score =  611 bits (1576), Expect = e-175
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 25  MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 84
           MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE
Sbjct: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60

Query: 85  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 144
           ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE
Sbjct: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120

Query: 145 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 204
           KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD
Sbjct: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180

Query: 205 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 264
           VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA
Sbjct: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240

Query: 265 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 324
           PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV
Sbjct: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300

Query: 325 CRAQTMSNSGIK 336
           CRAQTMSNSGIK
Sbjct: 301 CRAQTMSNSGIK 312


>gi|45006986 small inducible cytokine subfamily E, member 1 isoform
           a precursor [Homo sapiens]
          Length = 312

 Score =  611 bits (1576), Expect = e-175
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 25  MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 84
           MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE
Sbjct: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60

Query: 85  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 144
           ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE
Sbjct: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120

Query: 145 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 204
           KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD
Sbjct: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180

Query: 205 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 264
           VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA
Sbjct: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240

Query: 265 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 324
           PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV
Sbjct: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300

Query: 325 CRAQTMSNSGIK 336
           CRAQTMSNSGIK
Sbjct: 301 CRAQTMSNSGIK 312


>gi|4507947 tyrosyl-tRNA synthetase [Homo sapiens]
          Length = 528

 Score =  170 bits (430), Expect = 2e-42
 Identities = 86/171 (50%), Positives = 121/171 (70%), Gaps = 6/171 (3%)

Query: 156 EKKEKKQQSIAGSADSKPIDV--SRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTV 213
           +  ++K  +   + +S+P +V  SRLD+R+G IIT  KHPDADSLYVE++DVGE  PRTV
Sbjct: 343 DPSKQKPMAKGPAKNSEPEEVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTV 402

Query: 214 VSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSP---EKIEILAPPNGSV 270
           VSGLV  VP E++Q+R+V++LCNLKP KMRGV SQ M++CAS      ++E L PP GS 
Sbjct: 403 VSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSA 462

Query: 271 PGDRITFDAF-PGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVK 320
           PG+ +    +  G+PD+EL PKKK++E++Q D   ++EC+A +K   F  K
Sbjct: 463 PGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTK 513


>gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]
          Length = 567

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 37/155 (23%), Positives = 77/155 (49%), Gaps = 10/155 (6%)

Query: 20  RLLAKMAN-NDAVLKRLEQKGAEADQII----EYLKQQVSLLKEKAILQATLREEKK--- 71
           +L+A++ N N  +L+ +++   E +Q      E  +Q  +LL E  +L+    E ++   
Sbjct: 408 QLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMS 467

Query: 72  -LRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQST-AVTTV 129
            L+    +L  ++EEL + L + E +   +    P  +P H         ++ST A +T 
Sbjct: 468 ALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTP 527

Query: 130 SSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQS 164
           +   ++ + G  GD ++A  + E+  E++E+K Q+
Sbjct: 528 THCPQDSLSGVGGDVQEAFAQAEEGAEEEEEKMQN 562


>gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]
          Length = 597

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 37/155 (23%), Positives = 77/155 (49%), Gaps = 10/155 (6%)

Query: 20  RLLAKMAN-NDAVLKRLEQKGAEADQII----EYLKQQVSLLKEKAILQATLREEKK--- 71
           +L+A++ N N  +L+ +++   E +Q      E  +Q  +LL E  +L+    E ++   
Sbjct: 438 QLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMS 497

Query: 72  -LRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQST-AVTTV 129
            L+    +L  ++EEL + L + E +   +    P  +P H         ++ST A +T 
Sbjct: 498 ALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTP 557

Query: 130 SSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQS 164
           +   ++ + G  GD ++A  + E+  E++E+K Q+
Sbjct: 558 THCPQDSLSGVGGDVQEAFAQAEEGAEEEEEKMQN 592


>gi|116008447 CAP-GLY domain containing linker protein 2 isoform 1
           [Homo sapiens]
          Length = 1046

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 28/150 (18%)

Query: 32  LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI 91
           L++L+ +     Q IE+LK+Q+SL ++K +      + ++L+   A+ K+E+E L+++L+
Sbjct: 735 LEKLDVEYRGQAQAIEFLKEQISLAEKKML------DYERLQRAEAQGKQEVESLREKLL 788

Query: 92  QAEIQ-NGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEK 150
            AE +   V+ +     T +  ++ +SE  I+          TKE ++G           
Sbjct: 789 VAENRLQAVEALCSSQHTHMIESNDISEETIR----------TKETVEG----------- 827

Query: 151 IEKKGEKKEKKQQSIAGSADSKPIDVSRLD 180
           ++ K  K++K+  ++    +     VS L+
Sbjct: 828 LQDKLNKRDKEVTALTSQTEMLRAQVSALE 857



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 11/125 (8%)

Query: 54  SLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI--QAEIQNGVKQIPFPSGTPLH 111
           SLL EKA  +  LRE    R+     K  + +L++EL   + EI+  ++Q    SG P  
Sbjct: 476 SLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELTLRRGEIEE-LQQCLLHSGPPPP 534

Query: 112 ANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAK------EKIEKKGEKKEKKQQSI 165
            +   +E  I       +S+  + Q + G   +K  K       +++K     EK  Q +
Sbjct: 535 DHPDAAE--ILRLRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEV 592

Query: 166 AGSAD 170
           AG  D
Sbjct: 593 AGLKD 597


>gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2
           [Homo sapiens]
          Length = 1011

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 28/150 (18%)

Query: 32  LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI 91
           L++L+ +     Q IE+LK+Q+SL ++K +      + ++L+   A+ K+E+E L+++L+
Sbjct: 700 LEKLDVEYRGQAQAIEFLKEQISLAEKKML------DYERLQRAEAQGKQEVESLREKLL 753

Query: 92  QAEIQ-NGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEK 150
            AE +   V+ +     T +  ++ +SE  I+          TKE ++G           
Sbjct: 754 VAENRLQAVEALCSSQHTHMIESNDISEETIR----------TKETVEG----------- 792

Query: 151 IEKKGEKKEKKQQSIAGSADSKPIDVSRLD 180
           ++ K  K++K+  ++    +     VS L+
Sbjct: 793 LQDKLNKRDKEVTALTSQTEMLRAQVSALE 822


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 8/111 (7%)

Query: 54  SLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHAN 113
           S +K    L+   +E+++ R+EN + K+E E+L+++ ++ + +  ++++       L   
Sbjct: 518 SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKV 577

Query: 114 SMVSENVIQSTAVTTVSSGTKEQI--KGGTGDEKKAKEKIEKKGEKKEKKQ 162
               E V Q      +    K+QI  K    DEK  K K E+  E+K KK+
Sbjct: 578 LQARERVEQ------MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 32/171 (18%)

Query: 58  EKAILQAT-LREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMV 116
           +KA+ +A  L E  KLR E A+++K++EE  ++     +Q   ++     G  L   S+ 
Sbjct: 96  KKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSL- 154

Query: 117 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPID 175
            ENV+ S                        K+K +K  GEK EK +    G+  +K + 
Sbjct: 155 -ENVLDS------------------------KDKTQKSNGEKNEKCETKEKGAITAKELY 189

Query: 176 VSRLDLRIGCII-TARKHPD-ADSLYVEEVDVGE--IAPRTVVSGLVNHVP 222
               D  I  II  AR+  D  DS  +  + V E  I+P    S +  H+P
Sbjct: 190 TMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 32/171 (18%)

Query: 58  EKAILQAT-LREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMV 116
           +KA+ +A  L E  KLR E A+++K++EE  ++     +Q   ++     G  L   S+ 
Sbjct: 96  KKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSL- 154

Query: 117 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPID 175
            ENV+ S                        K+K +K  GEK EK +    G+  +K + 
Sbjct: 155 -ENVLDS------------------------KDKTQKSNGEKNEKCETKEKGAITAKELY 189

Query: 176 VSRLDLRIGCII-TARKHPD-ADSLYVEEVDVGE--IAPRTVVSGLVNHVP 222
               D  I  II  AR+  D  DS  +  + V E  I+P    S +  H+P
Sbjct: 190 TMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 32/171 (18%)

Query: 58  EKAILQAT-LREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMV 116
           +KA+ +A  L E  KLR E A+++K++EE  ++     +Q   ++     G  L   S+ 
Sbjct: 96  KKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSL- 154

Query: 117 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPID 175
            ENV+ S                        K+K +K  GEK EK +    G+  +K + 
Sbjct: 155 -ENVLDS------------------------KDKTQKSNGEKNEKCETKEKGAITAKELY 189

Query: 176 VSRLDLRIGCII-TARKHPD-ADSLYVEEVDVGE--IAPRTVVSGLVNHVP 222
               D  I  II  AR+  D  DS  +  + V E  I+P    S +  H+P
Sbjct: 190 TMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
            sapiens]
          Length = 1907

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 30/170 (17%)

Query: 40   AEADQIIEYLKQQVSLLKEK------AILQATLREEK------KLRVENAKLKKEIEELK 87
            +E  + IE LK  +S+   +      A+ +A L EEK      +++ ENA+LKK+ E+L+
Sbjct: 1305 SENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQ 1364

Query: 88   QEL-----IQAEIQNGVKQIPFPSG------TPLHANSMVSENVIQSTAVTTVSSGTKEQ 136
            QE+     + AE+   +K             T    N     N I    +    S ++ Q
Sbjct: 1365 QEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECESESEGQ 1424

Query: 137  IKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCI 186
             KGG   ++ A  ++   G++ EK +  I      + +DVSR    I  +
Sbjct: 1425 NKGGNDSDELANGEV--GGDRNEKMKNQI-----KQMMDVSRTQTAISVV 1467


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 24/150 (16%)

Query: 50  KQQVSLLKEKAILQATLREEKKLRVEN-AKLKKEIEELKQELIQAEIQNGVKQIPFPSGT 108
           K +  + K K  ++    E++K  +EN  +LKKEIEE+KQ   +  +++       P+  
Sbjct: 155 KLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGK-KWSLEDDDDDEDDPAEA 213

Query: 109 PLHANSMVSE-----NVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKI------------ 151
               N M  E     +         V       +KGG G+EKK+   +            
Sbjct: 214 EKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKA 273

Query: 152 -----EKKGEKKEKKQQSIAGSADSKPIDV 176
                +KKGE  E  Q ++  S++ + +D+
Sbjct: 274 VVDSDKKKGELMENDQDAMEYSSEEEEVDL 303


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 41/161 (25%), Positives = 83/161 (51%), Gaps = 21/161 (13%)

Query: 24   KMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEI 83
            K A  +A  + L+   AE D++    K ++ L ++   L+ +L +EKKLR++  + K+++
Sbjct: 1002 KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1061

Query: 84   E---ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGG 140
            E   +L QE I  +I+N  +Q+          +  + +   +   ++ + S  +++   G
Sbjct: 1062 EGDLKLAQESIM-DIENEKQQL----------DEKLKKKEFE---ISNLQSKIEDEQALG 1107

Query: 141  TGDEKKAKE---KIEKKGEKKEKKQQSIAGSADSKPIDVSR 178
               +KK KE   +IE+  E+ E ++ S A  A+ +  D+SR
Sbjct: 1108 IQLQKKIKELQARIEELEEEIEAERASRA-KAEKQRSDLSR 1147



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 33/144 (22%), Positives = 65/144 (45%), Gaps = 12/144 (8%)

Query: 22   LAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKK 81
            L    N   +LK  +    +A +  E LK+Q+++++ +A L     EE +  +E  +  +
Sbjct: 1646 LRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSR 1705

Query: 82   EIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGT 141
            +I E  QEL+ A  +    Q+     T     S+++      T ++ +    ++ ++   
Sbjct: 1706 KIAE--QELLDASER---VQLLHTQNT-----SLINTKKKLETDISQMQGEMEDILQEAR 1755

Query: 142  GDEKKAKEKIEKKGEKKE--KKQQ 163
              E+KAK+ I       E  KK+Q
Sbjct: 1756 NAEEKAKKAITDAAMMAEELKKEQ 1779


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 41/161 (25%), Positives = 83/161 (51%), Gaps = 21/161 (13%)

Query: 24   KMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEI 83
            K A  +A  + L+   AE D++    K ++ L ++   L+ +L +EKKLR++  + K+++
Sbjct: 1002 KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1061

Query: 84   E---ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGG 140
            E   +L QE I  +I+N  +Q+          +  + +   +   ++ + S  +++   G
Sbjct: 1062 EGDLKLAQESIM-DIENEKQQL----------DEKLKKKEFE---ISNLQSKIEDEQALG 1107

Query: 141  TGDEKKAKE---KIEKKGEKKEKKQQSIAGSADSKPIDVSR 178
               +KK KE   +IE+  E+ E ++ S A  A+ +  D+SR
Sbjct: 1108 IQLQKKIKELQARIEELEEEIEAERASRA-KAEKQRSDLSR 1147



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 33/144 (22%), Positives = 65/144 (45%), Gaps = 12/144 (8%)

Query: 22   LAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKK 81
            L    N   +LK  +    +A +  E LK+Q+++++ +A L     EE +  +E  +  +
Sbjct: 1646 LRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSR 1705

Query: 82   EIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGT 141
            +I E  QEL+ A  +    Q+     T     S+++      T ++ +    ++ ++   
Sbjct: 1706 KIAE--QELLDASER---VQLLHTQNT-----SLINTKKKLETDISQMQGEMEDILQEAR 1755

Query: 142  GDEKKAKEKIEKKGEKKE--KKQQ 163
              E+KAK+ I       E  KK+Q
Sbjct: 1756 NAEEKAKKAITDAAMMAEELKKEQ 1779


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)

Query: 37  QKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQ 96
           + G E D     +K       EK   +   R+E+K ++   K K+E+E  K++    + +
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKD----QSK 268

Query: 97  NGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGD---EKKAKEKIEK 153
               Q  F   T       V   V   T V   S    E       D   +KK K+K +K
Sbjct: 269 QKESQRKFEEET-------VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321

Query: 154 KGEKKEKKQQSIAG 167
           KGEK+EK+++   G
Sbjct: 322 KGEKEEKEKEKKKG 335


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 18/143 (12%)

Query: 20   RLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKL 79
            +L AK  +   + +  E K    ++ +E +KQ+   ++E      TL+  KKL  + AKL
Sbjct: 930  KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQE------TLK--KKLLDQEAKL 981

Query: 80   KKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKG 139
            KKE+E    EL Q E Q   K +         ANS        S AV+ + +  KEQI+ 
Sbjct: 982  KKELENTALELSQKEKQFNAKMLEM-----AQANSAGI-----SDAVSRLETNQKEQIES 1031

Query: 140  GTGDEKKAKEKIEKKGEKKEKKQ 162
             T   ++    +    EKK  +Q
Sbjct: 1032 LTEVHRRELNDVISIWEKKLNQQ 1054



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 34/158 (21%), Positives = 70/158 (44%), Gaps = 24/158 (15%)

Query: 32   LKRLEQKGAEADQII-------EYLKQQVSLLKEKAILQAT----LREEKK--------L 72
            L+  EQ+ AE  Q I       E + ++++ LKE+ + Q T    L+E+ K        L
Sbjct: 1066 LQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1125

Query: 73   RVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSG 132
              +  KLK  +E+L     + ++   +K+  F     +    +  E+  + + +T+    
Sbjct: 1126 AQDETKLKAHLEKL-----EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKT 1180

Query: 133  TKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSAD 170
            T E+ +      +K+ + +E K  + +K  + +A   D
Sbjct: 1181 TDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLD 1218



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 40/185 (21%), Positives = 79/185 (42%), Gaps = 24/185 (12%)

Query: 41  EADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVK 100
           E DQ I  L+ QVSLLK++            + V+  K   ++E   +   + E      
Sbjct: 216 EKDQYISVLQTQVSLLKQRL-------RNGPMNVDVLKPLPQLEPQAEVFTKEENPESDG 268

Query: 101 QIPFPSGT------PLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKK 154
           +     GT       L       EN+++    T  S   KEQ    T +++  +E+++++
Sbjct: 269 EPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSH--KEQCTLLTSEKEALQEQLDER 326

Query: 155 GEKKEK--------KQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVG 206
            ++ EK        K + I    D+K + + +L+   G +I   K    ++L ++E ++ 
Sbjct: 327 LQELEKIKDLHMAEKTKLITQLRDAKNL-IEQLEQDKGMVIAETKRQMHETLEMKEEEIA 385

Query: 207 EIAPR 211
           ++  R
Sbjct: 386 QLRSR 390


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 38/173 (21%), Positives = 80/173 (46%), Gaps = 21/173 (12%)

Query: 32  LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLR-EEKKLRVENAKLKKEIEELK--- 87
           L+ LE++ ++ D+    L++ V  LK  ++  A L+ E K+L  E  +LKK +E LK   
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF 748

Query: 88  ----------------QELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSS 131
                            + +Q  ++N  K+I     + L    M ++ + ++     +SS
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISS 807

Query: 132 GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIG 184
              EQ++      ++   ++EK  ++ EK+ + +   A+ K   +   +++IG
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 13/81 (16%)

Query: 27  NNDAVLKRLEQKGAEADQIIEYLKQ--QVS-------LLKEKAILQATLREEK----KLR 73
           N++  +K LEQ+    +Q +  L+Q  Q+S       + KE  IL  +++E      K+ 
Sbjct: 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIE 607

Query: 74  VENAKLKKEIEELKQELIQAE 94
            E  ++KKE+E  K++  +AE
Sbjct: 608 FEKRQIKKELEHYKEKGERAE 628


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 38/173 (21%), Positives = 80/173 (46%), Gaps = 21/173 (12%)

Query: 32  LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLR-EEKKLRVENAKLKKEIEELK--- 87
           L+ LE++ ++ D+    L++ V  LK  ++  A L+ E K+L  E  +LKK +E LK   
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF 748

Query: 88  ----------------QELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSS 131
                            + +Q  ++N  K+I     + L    M ++ + ++     +SS
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISS 807

Query: 132 GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIG 184
              EQ++      ++   ++EK  ++ EK+ + +   A+ K   +   +++IG
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 13/81 (16%)

Query: 27  NNDAVLKRLEQKGAEADQIIEYLKQ--QVS-------LLKEKAILQATLREEK----KLR 73
           N++  +K LEQ+    +Q +  L+Q  Q+S       + KE  IL  +++E      K+ 
Sbjct: 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIE 607

Query: 74  VENAKLKKEIEELKQELIQAE 94
            E  ++KKE+E  K++  +AE
Sbjct: 608 FEKRQIKKELEHYKEKGERAE 628


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 42/185 (22%), Positives = 86/185 (46%), Gaps = 20/185 (10%)

Query: 20   RLLAKMANNDAVLKRLEQKGAE-ADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAK 78
            +L  ++ +    L +LE +    A ++ E L++  S++KE+  L+   R E+ L++E  +
Sbjct: 1851 QLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLR---RVEETLKLERDQ 1907

Query: 79   LKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIK 138
            LK+ ++E K      EIQ  +K     S         + E + + T           QI 
Sbjct: 1908 LKESLQETKAR--DLEIQQELKTARMLSKEHKETVDKLREKISEKTI----------QIS 1955

Query: 139  GGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSL 198
                D  K+K++++KK ++ +KK+  +    +    DV+    +I  +   +K  +A +L
Sbjct: 1956 DIQKDLDKSKDELQKKIQELQKKELQLLRVKE----DVNMSHKKINEMEQLKKQFEAQNL 2011

Query: 199  YVEEV 203
             ++ V
Sbjct: 2012 SMQSV 2016



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 16/66 (24%), Positives = 37/66 (56%), Gaps = 12/66 (18%)

Query: 31   VLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQEL 90
            ++ +L+ K  E+++ +E  K+ + +L++K  L A               K+EIE+LK +L
Sbjct: 2417 IIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAK------------PYKEEIEDLKMKL 2464

Query: 91   IQAEIQ 96
            ++ +++
Sbjct: 2465 VKIDLE 2470


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 17/120 (14%)

Query: 46   IEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFP 105
            +  L+ Q  LL+E+  LQA  RE+  L+  N KL+++++EL  + I+ E Q         
Sbjct: 1047 LSQLESQNQLLQER--LQAEEREKTVLQSTNRKLERKVKELSIQ-IEDERQ--------- 1094

Query: 106  SGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSI 165
                 H N    +  ++  A+       +E+I+   G  KKA+ ++E++ E  E+ Q  I
Sbjct: 1095 -----HVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARI 1149



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 15/130 (11%)

Query: 55  LLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANS 114
           L K+ A+L+      ++L  +N +L+K +++L+Q+  +A   +  K +     T L    
Sbjct: 662 LEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEA---SKAKMVAEAEATVLGQRR 718

Query: 115 MVSENVIQSTAVTTVS-----SGTKEQIK-------GGTGDEKKAKEKIEKKGEKKEKKQ 162
              E  ++ T            G ++Q+K       GG   E + ++K+++   +K++ +
Sbjct: 719 AAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778

Query: 163 QSIAGSADSK 172
           +++  S + +
Sbjct: 779 EALNASQEEE 788


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 43/176 (24%), Positives = 79/176 (44%), Gaps = 14/176 (7%)

Query: 33  KRLEQKGAEADQIIEYLKQQVSLLKEKAIL-QATLREEKKLRVENAKLKKEIEELKQELI 91
           K+LEQK  E + + + L+++  + ++ A+  +    E  KLR EN +LKK+ E+L Q++I
Sbjct: 122 KQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDII 181

Query: 92  QAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKI 151
             +     KQI     T L      S+   Q +          ++I+  T    +A EKI
Sbjct: 182 DYQ-----KQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLT----EANEKI 232

Query: 152 EKKGEKKEKKQQSIAGSADSKPIDVSRLDLRI----GCIITARKHPDADSLYVEEV 203
           E + ++  K  +      +    + +R+   +      I   +K  D   L V+E+
Sbjct: 233 EVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQEL 288



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 19/151 (12%)

Query: 55   LLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHAN- 113
            L K++      LRE++++  EN +LK++I+ L   L                G PL  N 
Sbjct: 1826 LQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGL---------------QGKPLTDNK 1870

Query: 114  -SMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK--KGEKKEKKQQSIAGSAD 170
             S++ E   +   +     G  E++      EK AKE++ +  +G+K + K + I     
Sbjct: 1871 QSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLK 1930

Query: 171  SKPIDVSRLDLRIGCIITARKHPDADSLYVE 201
             K  +V  L  ++  +       D + L ++
Sbjct: 1931 EKEGEVFTLTKQLNTLKDLFAKADKEKLTLQ 1961



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 13/121 (10%)

Query: 32   LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI 91
            LK LE   A+ +Q I  LKQ V         +AT RE+K +   N  L+++I+ LK    
Sbjct: 2279 LKELETDIAKKNQSITDLKQLVK--------EATEREQK-VNKYNEDLEQQIKILKHVPE 2329

Query: 92   QAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKI 151
             AE + G+K+         H        +I         SG +  I     D  + KEKI
Sbjct: 2330 GAETEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTIP----DADQLKEKI 2385

Query: 152  E 152
            +
Sbjct: 2386 K 2386



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 32  LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKL-----RVENAKLKKEIEEL 86
           + +LE K ++     E L+++V L  +  I     R  K L     R EN  L KEIE L
Sbjct: 486 INKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESL 545

Query: 87  KQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV 120
           ++E  + +++  ++Q+    G     + + +E++
Sbjct: 546 EEE--RLDLKKKIRQMAQERGKRSATSGLTTEDL 577


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 39/186 (20%), Positives = 85/186 (45%), Gaps = 16/186 (8%)

Query: 14  RFMIFCRLLAK-MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKL 72
           R  I  R+LA  M N++  ++R +    E  Q+    +++     +K + +A L  EKK 
Sbjct: 273 RLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKH---QKQMERAMLENEKKK 329

Query: 73  RVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSG 132
           R    K K++IE  K+EL++      +KQI   +          +   ++       +  
Sbjct: 330 REMAEKEKEKIEREKEELMER-----LKQIEEQTKKAQQELEEQTRRALELEQERKRAQS 384

Query: 133 TKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKH 192
             E++     + ++AKE + +    ++K Q+ +A       ++++ L  RI  +  AR+ 
Sbjct: 385 EAEKLAKERQEAEEAKEALLQASRDQKKTQEQLA-------LEMAELTARISQLEMARQK 437

Query: 193 PDADSL 198
            +++++
Sbjct: 438 KESEAV 443


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 29/144 (20%)

Query: 49  LKQQVSLLKEKAILQATLREEKKL-RVENAKLKKEIEELKQELIQAEI-QNGVKQIPFPS 106
           +K +VSL+K K       RE+++L R E  K K+E   LKQ++ Q+   Q G+KQ+P  S
Sbjct: 558 IKDRVSLIKRK-------REQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSAS 610

Query: 107 -GTPLHANSMVSENV----------------IQSTAVTTVSSGTKEQIKGGTGDEKKAKE 149
            G P  + +  S +                  Q  +++ +S GT   +  G G     + 
Sbjct: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGT---VDSGQGSSVFTES 667

Query: 150 KIEKKGEKKEKKQQSIAGSADSKP 173
           ++  +       Q   A S  + P
Sbjct: 668 RVSSQQTVSYGSQHEQAHSTGTVP 691


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 33/145 (22%), Positives = 73/145 (50%), Gaps = 10/145 (6%)

Query: 30  AVLKRLEQKGAEADQIIEYLKQQVSLLK---EKAILQATLREEKKLRVENAKLKKEI--E 84
           A+ + L Q   + ++++  L+++ S L+    +A  +AT+  E++ R+E  +L++E+  +
Sbjct: 743 ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQ 802

Query: 85  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 144
            L+  L  AE      +   P  T  H  S + E + Q   ++   SG +++++    + 
Sbjct: 803 GLEGSLRVAEQAQEALEQQLP--TLRHERSQLQEQLAQ---LSRQLSGREQELEQARREA 857

Query: 145 KKAKEKIEKKGEKKEKKQQSIAGSA 169
           ++  E +E+   +KE   +  AG A
Sbjct: 858 QRQVEALERAAREKEALAKEHAGLA 882



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 21/81 (25%), Positives = 46/81 (56%), Gaps = 7/81 (8%)

Query: 21  LLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAK-L 79
           L A++      +KRLE++  E DQ+ + L +     K +A+    L+E+  L  E+ + L
Sbjct: 395 LSARVTELGLAVKRLEKQNLEKDQVNKDLTE-----KLEALESLRLQEQAALETEDGEGL 449

Query: 80  KKEIEELKQELIQAEIQNGVK 100
           ++ + +L Q ++ ++ ++GV+
Sbjct: 450 QQTLRDLAQAVL-SDSESGVQ 469


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 38/173 (21%), Positives = 80/173 (46%), Gaps = 21/173 (12%)

Query: 24   KMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEI 83
            K A  +A  + L+    E D++    K +V L ++   L+ +L +EKK+R++  + K+++
Sbjct: 998  KKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1057

Query: 84   E---ELKQELI------QAEIQNGVKQIPFPSGTPLHANSMVSEN---VIQSTAVTTVSS 131
            E   +L QE I      + +++  +K+  F        NS + +     +Q       + 
Sbjct: 1058 EGDLKLTQESIMDLENDKLQLEEKLKKKEFDIN---QQNSKIEDEQVLALQLQKKLKENQ 1114

Query: 132  GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSI------AGSADSKPIDVSR 178
               E+++     E+ A+ K+EK      ++ + I      AG A S  I++++
Sbjct: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 38/167 (22%), Positives = 77/167 (46%), Gaps = 18/167 (10%)

Query: 21   LLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLK 80
            L A++    AV+++ E+    A+Q +    ++V LL  +    + + ++KK+  +  +L+
Sbjct: 1683 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT--SLINQKKKMESDLTQLQ 1740

Query: 81   KEIEELKQELIQAEIQNG---------VKQIPFPSGTPLHANSMVSENVIQSTAVTTVSS 131
             E+EE  QE   AE +            +++     T  H   M  +N+ Q+        
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTIKDLQHRL 1799

Query: 132  GTKEQI--KGGTGDEKKAKEKI-EKKGE---KKEKKQQSIAGSADSK 172
               EQI  KGG    +K + ++ E +GE   ++++  +S+ G   S+
Sbjct: 1800 DEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSE 1846


>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 1112

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 2/119 (1%)

Query: 58  EKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVS 117
           EK   +   +E+K    E  K KK+ +E K E +   +       P P+  P+ +     
Sbjct: 747 EKKSKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTDECE 806

Query: 118 ENVIQSTAVTTVSSGTKEQIKGGTGDEKK-AKEKIEK-KGEKKEKKQQSIAGSADSKPI 174
           +   ++      + G  +  K     +KK  KEK E+ KG+KK KKQ   +  A  +P+
Sbjct: 807 DAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPV 865


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 4/82 (4%)

Query: 24   KMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEI 83
            K A  +A  + L+   AE D++    K +V L ++   L+ +L +EKK+R++  + K+++
Sbjct: 996  KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1055

Query: 84   E---ELKQELIQAEIQNGVKQI 102
            E   +L QE I  +++N  +Q+
Sbjct: 1056 EGDLKLTQESIM-DLENDKQQL 1076



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 14/159 (8%)

Query: 21   LLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLK 80
            L A++    AV+++ E+    A+Q +    ++V LL  +    + + ++KK+  + ++L+
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT--SLINQKKKMDADLSQLQ 1738

Query: 81   KEIEELKQELIQAEIQNG---------VKQIPFPSGTPLHANSMVSENVIQSTAVTTVSS 131
             E+EE  QE   AE +            +++     T  H   M  +N+ Q+        
Sbjct: 1739 TEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTIKDLQHRL 1797

Query: 132  GTKEQI--KGGTGDEKKAKEKIEKKGEKKEKKQQSIAGS 168
               EQI  KGG    +K + ++ +   + E +Q+  A S
Sbjct: 1798 DEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAES 1836


>gi|13540600 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform B [Homo sapiens]
          Length = 345

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 56  LKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSM 115
           ++  A L++ L E++ L V   +LK E  +L+QEL   E Q  V +   PS   L    M
Sbjct: 147 IERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKM 206

Query: 116 VSE-NVIQSTAVTTVSSGTK 134
            S      S   T V  GT+
Sbjct: 207 DSAVQASLSLPATPVGKGTE 226



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 25/113 (22%), Positives = 59/113 (52%), Gaps = 22/113 (19%)

Query: 43  DQIIEYLK--QQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVK 100
           D+++E+ +  +++    E  ++QA  R  + L+ +N +LK E+E LK++L + +     K
Sbjct: 35  DELVEFQEGSRELEAELEAQLVQAEQRN-RDLQADNQRLKYEVEALKEKL-EHQYAQSYK 92

Query: 101 QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK 153
           Q+           S++ +++ Q+ A+       KEQ+     + ++A + +E+
Sbjct: 93  QV-----------SVLEDDLSQTRAI-------KEQLHKYVRELEQANDDLER 127



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 34/168 (20%), Positives = 68/168 (40%), Gaps = 22/168 (13%)

Query: 26  ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEK------------AILQATLREEKKLR 73
           A  +A L + EQ+  +     + LK +V  LKEK            ++L+  L + + ++
Sbjct: 49  AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK 108

Query: 74  VENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGT 133
            +  K  +E+E+   +L +A+    V    F        N  +  N    + +       
Sbjct: 109 EQLHKYVRELEQANDDLERAKRATIVSLEDFEQ----RLNQAIERNAFLESEL-----DE 159

Query: 134 KEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKP-IDVSRLD 180
           KE +       K     + ++   +E++Q+    SA S P +D  ++D
Sbjct: 160 KESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMD 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,913,539
Number of Sequences: 37866
Number of extensions: 623749
Number of successful extensions: 5166
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 302
Number of HSP's that attempted gapping in prelim test: 4180
Number of HSP's gapped (non-prelim): 1200
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.