Guide to the Human Genome
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Search of human proteins with 215422375

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215422375 neural precursor cell expressed, developmentally
down-regulated 9 isoform 3 [Homo sapiens]
         (834 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215422375 neural precursor cell expressed, developmentally do...  1704   0.0  
gi|5453680 neural precursor cell expressed, developmentally down...  1694   0.0  
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]   514   e-145
gi|78486553 neural precursor cell expressed, developmentally dow...   314   2e-85
gi|55769585 HEF-like protein [Homo sapiens]                           265   2e-70
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r...   135   1e-31
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r...   132   1e-30
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r...   132   1e-30
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r...   132   1e-30
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s...   117   3e-26
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...   117   3e-26
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                50   1e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                50   1e-05
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    49   3e-05
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H...    49   3e-05
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]                       47   7e-05
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s...    47   7e-05
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    47   1e-04
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    47   1e-04
gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Ho...    46   1e-04
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    45   3e-04
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    45   3e-04
gi|27544941 myosin IF [Homo sapiens]                                   45   3e-04
gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]             45   3e-04
gi|20149528 proline-serine-threonine phosphatase interacting pro...    45   4e-04
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    44   6e-04
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    44   6e-04
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    44   6e-04
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]    44   6e-04
gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    44   8e-04

>gi|215422375 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 3 [Homo sapiens]
          Length = 834

 Score = 1704 bits (4412), Expect = 0.0
 Identities = 834/834 (100%), Positives = 834/834 (100%)

Query: 1   MWTRNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           MWTRNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV
Sbjct: 1   MWTRNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120
           KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV
Sbjct: 61  KLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120

Query: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIP 180
           PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIP
Sbjct: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIP 180

Query: 181 PSHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKD 240
           PSHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKD
Sbjct: 181 PSHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKD 240

Query: 241 YDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPN 300
           YDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPN
Sbjct: 241 YDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPN 300

Query: 301 HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRD 360
           HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRD
Sbjct: 301 HPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRD 360

Query: 361 LVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQAL 420
           LVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQAL
Sbjct: 361 LVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQAL 420

Query: 421 EMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELI 480
           EMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELI
Sbjct: 421 EMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELI 480

Query: 481 LHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPD 540
           LHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPD
Sbjct: 481 LHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPD 540

Query: 541 DAKQLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHN 600
           DAKQLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHN
Sbjct: 541 DAKQLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHN 600

Query: 601 KALPPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQ 660
           KALPPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQ
Sbjct: 601 KALPPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQ 660

Query: 661 LEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFI 720
           LEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFI
Sbjct: 661 LEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFI 720

Query: 721 SLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSS 780
           SLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSS
Sbjct: 721 SLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSS 780

Query: 781 NQLCEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834
           NQLCEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF
Sbjct: 781 NQLCEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834


>gi|5453680 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 1 [Homo sapiens]
          Length = 834

 Score = 1694 bits (4388), Expect = 0.0
 Identities = 830/831 (99%), Positives = 831/831 (100%)

Query: 4   RNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           +NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL
Sbjct: 4   KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63

Query: 64  IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG 123
           IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG
Sbjct: 64  IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG 123

Query: 124 HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSH 183
           HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSH
Sbjct: 124 HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSH 183

Query: 184 TTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKDYDF 243
           TTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKDYDF
Sbjct: 184 TTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPTKGVYAIPPSACRDEAGLREKDYDF 243

Query: 244 PPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP 303
           PPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP
Sbjct: 244 PPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP 303

Query: 304 PQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVD 363
           PQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVD
Sbjct: 304 PQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVD 363

Query: 364 GINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMG 423
           GINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMG
Sbjct: 364 GINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMG 423

Query: 424 VSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHN 483
           VSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHN
Sbjct: 424 VSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHN 483

Query: 484 KMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAK 543
           KMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAK
Sbjct: 484 KMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAK 543

Query: 544 QLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKAL 603
           QLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKAL
Sbjct: 544 QLTTTINTNAEALFRPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKAL 603

Query: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
           PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH
Sbjct: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663

Query: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
           HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL
Sbjct: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723

Query: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
           NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL
Sbjct: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783

Query: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834
           CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF
Sbjct: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF 834


>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
          Length = 870

 Score =  514 bits (1323), Expect = e-145
 Identities = 371/936 (39%), Positives = 489/936 (52%), Gaps = 180/936 (19%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGNR+K+L+
Sbjct: 5   NVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILV 64

Query: 65  G--------PMQETASSHEQPASGL-------------MQQTF---------------GQ 88
           G        P     ++  QP  GL             +  T+                Q
Sbjct: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124

Query: 89  QKLYQVPNPQA-----------------------APRDTIYQVPPSYQN--QGIYQVPTG 123
           Q LYQVP P                         +P   +YQVPP      Q IYQVP  
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPS 184

Query: 124 HGTQEQEVYQVPPSVQ-RSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQ--------- 173
            G    ++YQVPPS+  RS  GT  P    KV+ P R G GYVYE     Q         
Sbjct: 185 AG-MGHDIYQVPPSMDTRSWEGTKPP---AKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL 240

Query: 174 -----KDVYDIPP------SHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPT--K 220
                +D+YD+PP      S   Q VYD PP + KGP    P+ E     VYD+PP+  K
Sbjct: 241 LAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLE-----VYDVPPSVEK 295

Query: 221 G--------VYAIPPSACRDEAG---LREKDYDFPPPMRQAGRPD-LRPEGVYDIPPTCT 268
           G        VY +PPS  +D      LRE+ YD PP   +A   D  R   V   PP  +
Sbjct: 296 GLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDS 355

Query: 269 KPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEP 328
            PA +D++     D+P    P A     + P    P  G         YDVPR  + + P
Sbjct: 356 PPA-EDVY-----DVP----PPAPDLYDVPPGLRRPGPGT-------LYDVPR--ERVLP 396

Query: 329 PAETSEKANPQERD-GVYDVPLHNPPDAKGSRDLVDGINRLSFSSTGSTRSNMSTSSTSS 387
           P    E A+    D GVY VP   PP     R+      RLS SSTGSTRS+ S SS   
Sbjct: 397 P----EVADGGVVDSGVYAVP---PP---AEREAPAEGKRLSASSTGSTRSSQSASSLEV 446

Query: 388 KESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALV-----TTDWRCYGY-M 441
                 A P ++    L+ + A+E L RLQQ +   V+ L+ L      T  WR      
Sbjct: 447 ------AGPGREP---LELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQ 497

Query: 442 ERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQILSQ 501
           E  + +++ AV  V+  + E L F + AV NAA   +  LH K+ R+LQ++ED HQ L  
Sbjct: 498 EPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVA 557

Query: 502 TSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALFRPGP 561
               L+                  +DLDR V  ++ VP+DAKQL + ++ NA  LFR   
Sbjct: 558 HGQALDAGRGGSGATL--------EDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTK 609

Query: 562 GSLHLKNGPESIMNSTEYPHGGSQGQLLHPG--DHKAQAHNKALP--PGLSKEQAPDCSS 617
            +     GPE              G  LHP   D  +   ++ LP  P  + + +PD   
Sbjct: 610 ATAP---GPEG-------------GGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPD-GQ 652

Query: 618 SDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEHHQLSQFQLLEQEIT 677
            + SE  WM+DYDYVHLQGKEEFE+ QKELLEK +I +Q K QLE  QL QF+ LEQE++
Sbjct: 653 YENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVS 712

Query: 678 KPVENDISKWKPSQSL-PTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSA 736
           +P+++D++ W P+Q L P    G+   DRQLL FY +QCE +  +L NA+DA F+ V++ 
Sbjct: 713 RPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATN 772

Query: 737 QPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVMATKM 796
           QPP+IFVAHSKFVILSAHKLVFIGDTL+RQ  A D+R++V + SN LC+ L+ IV  TK 
Sbjct: 773 QPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKA 832

Query: 797 AALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
           AAL YPS +A Q+MV +V +L  + Q F+R L ++A
Sbjct: 833 AALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLA 868


>gi|78486553 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 2 [Homo sapiens]
          Length = 174

 Score =  314 bits (804), Expect = 2e-85
 Identities = 150/151 (99%), Positives = 151/151 (100%)

Query: 4   RNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           +NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL
Sbjct: 4   KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63

Query: 64  IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG 123
           IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG
Sbjct: 64  IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTG 123

Query: 124 HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKV 154
           HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKV
Sbjct: 124 HGTQEQEVYQVPPSVQRSIGGTSGPHVGKKV 154


>gi|55769585 HEF-like protein [Homo sapiens]
          Length = 786

 Score =  265 bits (676), Expect = 2e-70
 Identities = 247/871 (28%), Positives = 389/871 (44%), Gaps = 147/871 (16%)

Query: 6   LMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIG 65
           L+ARALYDN P+C++ELAF +GDILT++EQ+    EGWW C LHGRQG+ P NR+++L  
Sbjct: 14  LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL-- 71

Query: 66  PMQETASSHEQP--ASGLMQQTFGQQKLYQVPN-PQAAPRDTIYQVPPSYQNQGIYQVPT 122
              E A+    P    GL +     ++ YQVP  P+      +Y+   S+      Q PT
Sbjct: 72  --TEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGP--QPPT 127

Query: 123 GHGTQEQEVYQV--PPSVQRSIGGTSGPHVGKKVIT---PVR----TGHGYVYEYPSRY- 172
                  +VY+   PP+  R I   +     + ++T   PVR    T    VY+ P+++ 
Sbjct: 128 A------QVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHR 181

Query: 173 ---------QKDVYDIPPSHTTQGVYDIPPSSAKG---PVFSVPV----------GEIKP 210
                    ++ +YDIP S    G++  P S A G   P+ SV               K 
Sbjct: 182 GPVVLKEPEKQQLYDIPASPKKAGLHP-PDSQASGQGVPLISVTTLRRGGYSTLPNPQKS 240

Query: 211 QGVYDIPPTKGVYAI---PPSACRDEA---GLREKDYDFPPPMRQAGRPDLRPEGVYDIP 264
           + +YD P + G  ++   P ++  +E+    L      F  P     R  L P+   ++P
Sbjct: 241 EWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSR-SLTPQLNNNVP 299

Query: 265 PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQN---DAYDVPR 321
               K         Y   +P    P+    + +S   P   L   V  QN   + YD+P+
Sbjct: 300 --MQKKLSLPEIPSYGFLVPRGTFPL---DEDVSYKVPSSFLIPRVEQQNTKPNIYDIPK 354

Query: 322 GVQFLEPPAETSEKANPQERDGVYDVPLHNPP-DAKGSRDLVDGINRLSFSSTGSTRSNM 380
               +    +  EKA     +       HN    ++ +       +RLS SS+ S  S +
Sbjct: 355 ATSSVSQAGKELEKAKEVSENSAG----HNSSWFSRRTTSPSPEPDRLSGSSSDSRASIV 410

Query: 381 ST-SSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALVTTDWRCYG 439
           S+ S+TS+ +SS S+S    K L LD D A E +  LQ  +   V+ LM  V+  WR   
Sbjct: 411 SSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRD 470

Query: 440 YMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQIL 499
           Y+E +I+ I  + D +E  ++E+L F +G    A  L +  L N+++ ++Q + +S++IL
Sbjct: 471 YLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRIL 530

Query: 500 SQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALFRP 559
            +T   L+  +W L +L  +  QN  DDL+RFVMVA+ +P+D K+  + +  N   LF+ 
Sbjct: 531 LETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKR 590

Query: 560 GPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKALPPGLSKEQAPDCSSSD 619
                  K     +  + E+       + + P   + ++H K+ P   S +Q  D  SS 
Sbjct: 591 NCE----KEETVQLTPNAEF----KCEKYIQPPQRETESHQKSTP---STKQREDEHSS- 638

Query: 620 GSERSWMDDYDYVHLQGKEEFERQQKELLEKE--NIMKQNKMQLEHHQLSQFQLLEQEIT 677
                                     ELL+K   NI  QN   L              I 
Sbjct: 639 --------------------------ELLKKNRANICGQNPGPL--------------IP 658

Query: 678 KPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSAQ 737
           +P      + KP  S                    + C  +F +L  AI A    +SS+Q
Sbjct: 659 QPSSQQTPERKPRLS--------------------EHCRLYFGALFKAISAFHGSLSSSQ 698

Query: 738 PPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVMATKMA 797
           P  I +  SK VI+   KLV   DTL  +   +D+RN+++  S+ LC  LK + +ATK A
Sbjct: 699 PAEI-ITQSKLVIMVGQKLV---DTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNA 754

Query: 798 ALHYPSTTALQEMVHQVTDLSRNAQLFKRSL 828
            L YPS  AL  +  +   L ++ + F+ +L
Sbjct: 755 VLTYPSPAALGHLQAEAEKLEQHTRQFRGTL 785


>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 353

 Score =  135 bits (341), Expect = 1e-31
 Identities = 111/325 (34%), Positives = 150/325 (46%), Gaps = 38/325 (11%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGI+PGN +K+L+
Sbjct: 5   NVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILV 64

Query: 65  --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114
                   GP     ++  QP  GL        Q    +PN      D++Y VP PS   
Sbjct: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124

Query: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174
           QG+YQVP   G   Q  +Q PP+ Q S      PH          T    V   P    +
Sbjct: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH---HPFPSPATDLYQVSPGPGGPAQ 176

Query: 175 DVYDIPPS-HTTQGVYDIPPS-------SAKGPVFSVPVGE---IKPQGVYDIPPTKGVY 223
           D+Y +PPS      +Y +P S         K P     V     + P+G+   P    +Y
Sbjct: 177 DIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGL-GSPSFLLIY 235

Query: 224 AIPPSA----CRDEAGLREKDYDFPPPMRQAGRPDL--RPEGVYDIPPTCTKPAGKDLHV 277
             P  A    CR   G   + + + P + +  +P L   P      P  C+      +HV
Sbjct: 236 LSPAPARGEPCRALTGHLSQRH-WAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHV 294

Query: 278 -KYNCDIPGAAEPVARRHQSLSPNH 301
            K     P A+ PV  R    S  H
Sbjct: 295 EKEAVTTPEASSPVRSRGTPRSSRH 319


>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 232

 Score =  132 bits (333), Expect = 1e-30
 Identities = 85/213 (39%), Positives = 114/213 (53%), Gaps = 35/213 (16%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +K+L+
Sbjct: 5   NVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILV 64

Query: 65  --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114
                   GP     ++  QP  GL        Q    +PN      D++Y VP PS   
Sbjct: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124

Query: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174
           QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS    
Sbjct: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPSP-AT 162

Query: 175 DVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
           D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 163 DLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 33/153 (21%), Positives = 58/153 (37%), Gaps = 29/153 (18%)

Query: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141

Query: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPTCTKPAGKDLHVKYNCDI 283
           +        +   + FP P     +    P G    +Y +PP+     G D++      +
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA--GMGHDIY-----QV 194

Query: 284 PGAAEPVARRHQSLSP---NHPPPQLGQSVGSQ 313
           P + +   R  +   P    +P P +G + G Q
Sbjct: 195 PSSMD--TRSWEGTKPPAKANPSPLMGHARGQQ 225


>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 224

 Score =  132 bits (333), Expect = 1e-30
 Identities = 85/213 (39%), Positives = 114/213 (53%), Gaps = 35/213 (16%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +K+L+
Sbjct: 5   NVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILV 64

Query: 65  --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114
                   GP     ++  QP  GL        Q    +PN      D++Y VP PS   
Sbjct: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124

Query: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174
           QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS    
Sbjct: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPSP-AT 162

Query: 175 DVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
           D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 163 DLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 17/103 (16%)

Query: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141

Query: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPT 266
           +        +   + FP P     +    P G    +Y +PP+
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPS 184


>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 368

 Score =  132 bits (333), Expect = 1e-30
 Identities = 85/213 (39%), Positives = 114/213 (53%), Gaps = 35/213 (16%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           N++A+ALY NV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +K+L+
Sbjct: 5   NVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILV 64

Query: 65  --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114
                   GP     ++  QP  GL        Q    +PN      D++Y VP PS   
Sbjct: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124

Query: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174
           QG+YQVP   G   Q  +Q PP+ Q S      PH                + +PS    
Sbjct: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPSP-AT 162

Query: 175 DVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
           D+Y +   P    Q +Y +PPS+  G  ++ VP
Sbjct: 163 DLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 22/145 (15%)

Query: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
           P+    G++  +PP+S   P            V+ VP      QG+Y +P     +  PP
Sbjct: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141

Query: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPTCTKPAGKDLH-VKYNCD 282
           +        +   + FP P     +    P G    +Y +PP+     G D++ V  + D
Sbjct: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA--GMGHDIYQVPSSMD 199

Query: 283 IPG--AAEPVARRHQSLSPNHPPPQ 305
                  +P A+     SP   PP+
Sbjct: 200 TRSWEGTKPPAKCASVSSPRCLPPR 224


>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
           sapiens]
          Length = 468

 Score =  117 bits (294), Expect = 3e-26
 Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)

Query: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
           P G   E  P    ++       ++YDYVHL+G ++                Q     + 
Sbjct: 263 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 307

Query: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
                 +L E+ +  P E       P + L      VS  D QLL FY  QC++H+ +L 
Sbjct: 308 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 358

Query: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
            A+ AL S   + QPPR+FV HSK V+++AH+LVF+GDTL R   +  +R +V  +   L
Sbjct: 359 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 418

Query: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
            + L+  V+A K AAL YPS+ A+QEMV  VT+L+  A  F   L  +A
Sbjct: 419 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 467



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 69/269 (25%), Positives = 91/269 (33%), Gaps = 73/269 (27%)

Query: 131 VYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS---------RYQKDVYDIPP 181
           VY VPP  +     TSGP  G     P       +Y+ P          R   +VYD+PP
Sbjct: 7   VYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP 59

Query: 182 SHT---TQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP--------------- 217
           +     + G YD P S      FS P+  + PQ        YD+P               
Sbjct: 60  TALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEW 113

Query: 218 -----PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIP------PT 266
                P   +YA P +  R  A L    Y+ P  +   G      EG+YD+P      P 
Sbjct: 114 EGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLLGPEAPP 171

Query: 267 CTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQNDAYDVPRGVQ 324
             +P G       + D    A+ +AR   S  P H P  P           A  VP    
Sbjct: 172 SPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPLPALPVPEA-- 222

Query: 325 FLEPPAETSEKANPQERDGVYDVPLHNPP 353
              P         P  +  + D PL  PP
Sbjct: 223 ---PSPSPVPSPAPGRKGSIQDRPLPPPP 248


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score =  117 bits (294), Expect = 3e-26
 Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)

Query: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
           P G   E  P    ++       ++YDYVHL+G ++                Q     + 
Sbjct: 356 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 400

Query: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
                 +L E+ +  P E       P + L      VS  D QLL FY  QC++H+ +L 
Sbjct: 401 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 451

Query: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
            A+ AL S   + QPPR+FV HSK V+++AH+LVF+GDTL R   +  +R +V  +   L
Sbjct: 452 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 511

Query: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
            + L+  V+A K AAL YPS+ A+QEMV  VT+L+  A  F   L  +A
Sbjct: 512 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 560



 Score =  117 bits (293), Expect = 4e-26
 Identities = 120/399 (30%), Positives = 157/399 (39%), Gaps = 110/399 (27%)

Query: 3   TRNLMARALYDNVPECAEELAFRKGDILTVIE-QNTGGLEGWWLCSLHGRQGIVPGNRVK 61
           T   +ARALYDN  E  +EL+FR+GD+L V++ +  GGL+GW LCSLHG+QGIVP NRVK
Sbjct: 5   TSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVK 64

Query: 62  LL-IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120
           LL  GP  + + S   PA              Q  +P  AP                   
Sbjct: 65  LLPAGPAPKPSLSPASPA--------------QPGSPYPAP------------------- 91

Query: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYP---------SR 171
              H  ++QEVY VPP  +     TSGP  G     P       +Y+ P          R
Sbjct: 92  --DHSNEDQEVYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPR 142

Query: 172 YQKDVYDIPPSH---TTQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP----- 217
              +VYD+PP+     + G YD P S      FS P+  + PQ        YD+P     
Sbjct: 143 DALEVYDVPPTALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKP 196

Query: 218 ---------------PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYD 262
                          P   +YA P +  R  A L    Y+ P  +   G      EG+YD
Sbjct: 197 PAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYD 254

Query: 263 IP------PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQN 314
           +P      P   +P G       + D    A+ +AR   S  P H P  P          
Sbjct: 255 VPLLGPEAPPSPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPL 307

Query: 315 DAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPP 353
            A  VP       P         P  +  + D PL  PP
Sbjct: 308 PALPVPEA-----PSPSPVPSPAPGRKGSIQDRPLPPPP 341


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 19/100 (19%)

Query: 6    LMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIG 65
            L A+ALY    +    L F K D++TV+EQ     + WW   + G++G  P + VKL+ G
Sbjct: 916  LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ----DMWWFGEVQGQKGWFPKSYVKLISG 971

Query: 66   PMQETAS----SHEQPASGLMQQTFGQQKLYQVPNPQAAP 101
            P++++ S    S E PAS           L +V +P A P
Sbjct: 972  PIRKSTSMDSGSSESPAS-----------LKRVASPAAKP 1000



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 11   LYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            +YD   +  +ELAF KG I+ V+ +       WW   ++G+ G+ P N VKL
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKED---PDWWKGEVNGQVGLFPSNYVKL 1211


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 19/100 (19%)

Query: 6    LMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIG 65
            L A+ALY    +    L F K D++TV+EQ     + WW   + G++G  P + VKL+ G
Sbjct: 916  LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ----DMWWFGEVQGQKGWFPKSYVKLISG 971

Query: 66   PMQETAS----SHEQPASGLMQQTFGQQKLYQVPNPQAAP 101
            P++++ S    S E PAS           L +V +P A P
Sbjct: 972  PIRKSTSMDSGSSESPAS-----------LKRVASPAAKP 1000



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 11   LYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL--IGPMQ 68
            +YD   +  +ELAF KG I+ V+ +       WW   ++G+ G+ P N VKL   + P Q
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKED---PDWWKGEVNGQVGLFPSNYVKLTTDMDPSQ 1219

Query: 69   ETAS 72
            +  S
Sbjct: 1220 QWCS 1223


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           R L+D  PE  +ELA R+GD++ V+ + T   +GWW     GR+G+ P N V
Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFV 237



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 22/100 (22%)

Query: 16  PECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL-IGPMQETASSH 74
           PE A+EL  + G+I+ +I++     +GWWL   +G+ G  P N V+LL  GP   +  + 
Sbjct: 96  PEQADELKLQAGEIVEMIKEIE---DGWWLGKKNGQLGAFPSNFVELLDSGP--PSLGNP 150

Query: 75  EQPASGLMQQTFGQQKLYQVPNPQAAPR--DTIYQVPPSY 112
           + P+                P PQ  P+     Y  PP Y
Sbjct: 151 DMPSVS--------------PGPQRPPKLSSLAYDSPPDY 176


>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
           sapiens]
          Length = 645

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
           R L+D  PE  +ELA R+GD++ V+ + T   +GWW     GR+G+ P N V
Sbjct: 76  RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFV 126



 Score = 30.0 bits (66), Expect = 9.3
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 19/75 (25%)

Query: 41  EGWWLCSLHGRQGIVPGNRVKLL-IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQA 99
           +GWWL   +G+ G  P N V+LL  GP   +  + + P+                P PQ 
Sbjct: 7   DGWWLGKKNGQLGAFPSNFVELLDSGP--PSLGNPDMPSVS--------------PGPQR 50

Query: 100 APR--DTIYQVPPSY 112
            P+     Y  PP Y
Sbjct: 51  PPKLSSLAYDSPPDY 65


>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
          Length = 352

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           RALYD  PE   EL F++GDI+T+  Q     E W+   LHG  G  P N V++L+
Sbjct: 296 RALYDFEPENEGELGFKEGDIITLTNQID---ENWYEGMLHGHSGFFPINYVEILV 348


>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
           sapiens]
          Length = 486

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 6   LMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           + A ALYD   E ++EL+F   D++T IE      EGWW    HG  G+ P N VKLL
Sbjct: 431 ISAVALYDYQGEGSDELSFDPDDVITDIEMVD---EGWWRGRCHGHFGLFPANYVKLL 485


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%)

Query: 10  ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGN 58
           AL+D   E  +EL+FR+G+ +TV+ ++      WW  +LHG++G VP N
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRN 813



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/84 (27%), Positives = 30/84 (35%)

Query: 293 RHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNP 352
           R+ S S   P    G    +  D  D P G     P        +P+ R      PL+  
Sbjct: 69  RYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQ 128

Query: 353 PDAKGSRDLVDGINRLSFSSTGST 376
           PDA GS D        +F   GS+
Sbjct: 129 PDAYGSLDRATSPRPRAFDGAGSS 152


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%)

Query: 10  ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGN 58
           AL+D   E  +EL+FR+G+ +TV+ ++      WW  +LHG++G VP N
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRN 813



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/84 (27%), Positives = 30/84 (35%)

Query: 293 RHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNP 352
           R+ S S   P    G    +  D  D P G     P        +P+ R      PL+  
Sbjct: 69  RYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQ 128

Query: 353 PDAKGSRDLVDGINRLSFSSTGST 376
           PDA GS D        +F   GS+
Sbjct: 129 PDAYGSLDRATSPRPRAFDGAGSS 152


>gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Homo
           sapiens]
          Length = 847

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 29/69 (42%), Positives = 37/69 (53%), Gaps = 3/69 (4%)

Query: 10  ALYDNVPECAEELAFRKGDILTVIEQNTG--GLEGWWLCSLHGRQGIVPGNRVKLLIGPM 67
           AL+D  P   +ELA RKGD + V+ ++    G EGWW   + G+ GI P N V    GP 
Sbjct: 48  ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGGGPP 107

Query: 68  Q-ETASSHE 75
             E AS  E
Sbjct: 108 PCEVASFQE 116


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 4   RNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           R    +  +  +P+  +EL  + GDI+ V+ +     EGWW   L+G+ G+ P N +K L
Sbjct: 62  RRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVE---EGWWEGVLNGKTGMFPSNFIKEL 118

Query: 64  IGPMQETA-SSHEQPASGLMQQTFGQQ 89
            G   E   S  EQ +   +++T G +
Sbjct: 119 SGESDELGISQDEQLSKSSLRETTGSE 145



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 1/58 (1%)

Query: 20  EELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETASSHEQP 77
           +EL  ++GDI+T+I ++   + GWW   L+GR+G+ P N VKLL    ++  +  ++P
Sbjct: 247 DELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKP 303


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 4   RNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           R    +  +  +P+  +EL  + GDI+ V+ +     EGWW   L+G+ G+ P N +K L
Sbjct: 99  RRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVE---EGWWEGVLNGKTGMFPSNFIKEL 155

Query: 64  IGPMQETA-SSHEQPASGLMQQTFGQQ 89
            G   E   S  EQ +   +++T G +
Sbjct: 156 SGESDELGISQDEQLSKSSLRETTGSE 182



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 1/58 (1%)

Query: 20  EELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETASSHEQP 77
           +EL  ++GDI+T+I ++   + GWW   L+GR+G+ P N VKLL    ++  +  ++P
Sbjct: 284 DELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKP 340



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 3/80 (3%)

Query: 12 YDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQETA 71
          +D   +  +EL    G+I+T I +  GG   WW   ++GR+G+ P N V+ +   M++  
Sbjct: 8  FDYQAQHDDELTISVGEIITNIRKEDGG---WWEGQINGRRGLFPDNFVREIKKEMKKDP 64

Query: 72 SSHEQPASGLMQQTFGQQKL 91
           +++ P   L +   G   L
Sbjct: 65 LTNKAPEKPLHEVPSGNSLL 84


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 3/59 (5%)

Query: 3    TRNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVK 61
            T     RALY  V +  +EL+F   +++ ++ ++  G   WW   LHG++G+ PGN V+
Sbjct: 1041 THGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSG---WWKGRLHGQEGLFPGNYVE 1096


>gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]
          Length = 403

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 2/61 (3%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTV-IEQNTGGLEGWWLCSLHGR-QGIVPGNRVKL 62
           +++ARA YD      EE++FR GD+L + +++    + GW L SL G+  G++P N VK+
Sbjct: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333

Query: 63  L 63
           L
Sbjct: 334 L 334


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 3/55 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
           RALYD   +  +EL    GDIL VI +   G +GWW    +G++G VPG+ ++ L
Sbjct: 365 RALYDYTAQNPDELDLSAGDILEVILE---GEDGWWTVERNGQRGFVPGSYLEKL 416


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 13/109 (11%)

Query: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
           NL A+AL     +    L F K DI+TV+EQ     E WW   +HG +G  P + VK++ 
Sbjct: 873 NLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ----ENWWFGEVHGGRGWFPKSYVKIIP 928

Query: 65  G-------PMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIY 106
           G       P    A+ +++P S     + G++ +   P     P D  +
Sbjct: 929 GSEVKREEPEALYAAVNKKPTSA--AYSVGEEYIALYPYSSVEPGDLTF 975



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            A+YD      +EL+F KG ++ V+ ++      WW   ++G  G+ P N VK+
Sbjct: 1107 AMYDYAANNEDELSFSKGQLINVMNKDD---PDWWQGEINGVTGLFPSNYVKM 1156



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQ 68
           RALY       +E++F  GDI+ V ++ T G  GW   S  G  G  P N V+ +     
Sbjct: 736 RALYPFEARNHDEMSFNSGDIIQV-DEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSEN 794

Query: 69  ETASSHEQPASGLMQQT 85
           E A S   P   L+  T
Sbjct: 795 EKAVS---PKKALLPPT 808



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 19   AEELAFRKGDILTVIEQNTGGLEGWWLCSLHGR-----QGIVPGNRVKLLIGPMQETASS 73
            +E+L+   G ++ ++++NT    GWW   L  R     +G  P + VKLL GP  E A+ 
Sbjct: 1042 SEQLSLAPGQLILILKKNT---SGWWQGELQARGKKRQKGWFPASHVKLL-GPSSERATP 1097

Query: 74   HEQP 77
               P
Sbjct: 1098 AFHP 1101


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 13/109 (11%)

Query: 5    NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
            NL A+AL     +    L F K DI+TV+EQ     E WW   +HG +G  P + VK++ 
Sbjct: 900  NLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ----ENWWFGEVHGGRGWFPKSYVKIIP 955

Query: 65   G-------PMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIY 106
            G       P    A+ +++P S     + G++ +   P     P D  +
Sbjct: 956  GSEVKREEPEALYAAVNKKPTSA--AYSVGEEYIALYPYSSVEPGDLTF 1002



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            A+YD      +EL+F KG ++ V+ ++      WW   ++G  G+ P N VK+
Sbjct: 1134 AMYDYAANNEDELSFSKGQLINVMNKDD---PDWWQGEINGVTGLFPSNYVKM 1183



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQ 68
           RALY       +E++F  GDI+ V ++ T G  GW   S  G  G  P N V+ +     
Sbjct: 763 RALYPFEARNHDEMSFNSGDIIQV-DEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSEN 821

Query: 69  ETASSHEQPASGLMQQT 85
           E A S   P   L+  T
Sbjct: 822 EKAVS---PKKALLPPT 835



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 19   AEELAFRKGDILTVIEQNTGGLEGWWLCSLHGR-----QGIVPGNRVKLLIGPMQETASS 73
            +E+L+   G ++ ++++NT    GWW   L  R     +G  P + VKLL GP  E A+ 
Sbjct: 1069 SEQLSLAPGQLILILKKNT---SGWWQGELQARGKKRQKGWFPASHVKLL-GPSSERATP 1124

Query: 74   HEQP 77
               P
Sbjct: 1125 AFHP 1128


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 13/109 (11%)

Query: 5    NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
            NL A+AL     +    L F K DI+TV+EQ     E WW   +HG +G  P + VK++ 
Sbjct: 900  NLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ----ENWWFGEVHGGRGWFPKSYVKIIP 955

Query: 65   G-------PMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIY 106
            G       P    A+ +++P S     + G++ +   P     P D  +
Sbjct: 956  GSEVKREEPEALYAAVNKKPTSA--AYSVGEEYIALYPYSSVEPGDLTF 1002



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKL 62
            A+YD      +EL+F KG ++ V+ ++      WW   ++G  G+ P N VK+
Sbjct: 1134 AMYDYAANNEDELSFSKGQLINVMNKDD---PDWWQGEINGVTGLFPSNYVKM 1183



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 9   RALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQ 68
           RALY       +E++F  GDI+ V ++ T G  GW   S  G  G  P N V+ +     
Sbjct: 763 RALYPFEARNHDEMSFNSGDIIQV-DEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSEN 821

Query: 69  ETASSHEQPASGLMQQT 85
           E A S   P   L+  T
Sbjct: 822 EKAVS---PKKALLPPT 835



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)

Query: 19   AEELAFRKGDILTVIEQNTGGLEGWWLCSLHGR-----QGIVPGNRVKLLIGPMQETASS 73
            +E+L+   G ++ ++++NT    GWW   L  R     +G  P + VKLL GP  E A+ 
Sbjct: 1069 SEQLSLAPGQLILILKKNT---SGWWQGELQARGKKRQKGWFPASHVKLL-GPSSERATP 1124

Query: 74   HEQP 77
               P
Sbjct: 1125 AFHP 1128


>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
          Length = 1090

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 7    MARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL--I 64
            +A AL+D   + ++EL+F +GD LT++ +       WW   L  R+G VP N + L   I
Sbjct: 1023 VAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYPRI 1082

Query: 65   GPMQET 70
             P Q T
Sbjct: 1083 KPRQRT 1088


>gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
            isoform 2 [Homo sapiens]
          Length = 2472

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 7/83 (8%)

Query: 10   ALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIGPMQE 69
            ALYD   +   E+  +KGDILT++       + WW   ++ RQG VP   VK L  P Q 
Sbjct: 974  ALYDYQEKSPREVTMKKGDILTLLNSTN---KDWWKVEVNDRQGFVPAAYVKKL-DPAQS 1029

Query: 70   TASSH---EQPASGLMQQTFGQQ 89
             +  +   EQ +  L Q+    Q
Sbjct: 1030 ASRENLLEEQGSIALRQEQIDNQ 1052


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,525,624
Number of Sequences: 37866
Number of extensions: 1949988
Number of successful extensions: 7543
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 265
Number of HSP's that attempted gapping in prelim test: 6920
Number of HSP's gapped (non-prelim): 662
length of query: 834
length of database: 18,247,518
effective HSP length: 111
effective length of query: 723
effective length of database: 14,044,392
effective search space: 10154095416
effective search space used: 10154095416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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