BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo sapiens] (1977 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo... 3936 0.0 gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo... 3927 0.0 gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo s... 3925 0.0 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 74 2e-12 gi|91982772 mucin 17 [Homo sapiens] 71 9e-12 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 68 1e-10 gi|150170670 piccolo isoform 2 [Homo sapiens] 67 2e-10 gi|150378539 piccolo isoform 1 [Homo sapiens] 67 2e-10 gi|209862789 microtubule associated monoxygenase, calponin and L... 60 2e-08 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 60 2e-08 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 60 2e-08 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 60 2e-08 gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 59 6e-08 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 2e-07 gi|87299628 biorientation of chromosomes in cell division 1-like... 53 3e-06 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 53 3e-06 gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 53 3e-06 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 51 1e-05 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 51 1e-05 gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 51 1e-05 gi|226437579 NAC alpha domain containing [Homo sapiens] 50 3e-05 gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 50 3e-05 gi|41281453 serine/threonine kinase 2 [Homo sapiens] 49 6e-05 gi|210032580 SET domain containing 1B [Homo sapiens] 48 1e-04 gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 47 2e-04 gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens] 47 2e-04 gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 47 2e-04 gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 47 2e-04 gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 47 2e-04 gi|11968023 zinc finger protein 106 homolog [Homo sapiens] 47 2e-04 >gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo sapiens] Length = 1977 Score = 3936 bits (10208), Expect = 0.0 Identities = 1977/1977 (100%), Positives = 1977/1977 (100%) Query: 1 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE 60 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE Sbjct: 1 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE 60 Query: 61 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN 120 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN Sbjct: 61 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN 120 Query: 121 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL 180 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL Sbjct: 121 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL 180 Query: 181 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD 240 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD Sbjct: 181 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD 240 Query: 241 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP 300 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP Sbjct: 241 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP 300 Query: 301 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 360 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL Sbjct: 301 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 360 Query: 361 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 420 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV Sbjct: 361 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 420 Query: 421 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 480 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK Sbjct: 421 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 480 Query: 481 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 540 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR Sbjct: 481 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 540 Query: 541 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 600 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD Sbjct: 541 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 600 Query: 601 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 660 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP Sbjct: 601 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 660 Query: 661 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA 720 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA Sbjct: 661 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA 720 Query: 721 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL 780 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL Sbjct: 721 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL 780 Query: 781 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 840 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL Sbjct: 781 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 840 Query: 841 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF 900 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF Sbjct: 841 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF 900 Query: 901 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV 960 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV Sbjct: 901 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV 960 Query: 961 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER 1020 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER Sbjct: 961 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER 1020 Query: 1021 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE 1080 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE Sbjct: 1021 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE 1080 Query: 1081 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN 1140 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN Sbjct: 1081 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN 1140 Query: 1141 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT 1200 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT Sbjct: 1141 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT 1200 Query: 1201 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT 1260 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT Sbjct: 1201 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT 1260 Query: 1261 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT 1320 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT Sbjct: 1261 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT 1320 Query: 1321 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC 1380 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC Sbjct: 1321 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC 1380 Query: 1381 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS 1440 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS Sbjct: 1381 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS 1440 Query: 1441 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW 1500 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW Sbjct: 1441 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW 1500 Query: 1501 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA 1560 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA Sbjct: 1501 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA 1560 Query: 1561 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA 1620 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA Sbjct: 1561 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA 1620 Query: 1621 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE 1680 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE Sbjct: 1621 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE 1680 Query: 1681 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL 1740 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL Sbjct: 1681 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL 1740 Query: 1741 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ 1800 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ Sbjct: 1741 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ 1800 Query: 1801 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE 1860 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE Sbjct: 1801 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE 1860 Query: 1861 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG 1920 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG Sbjct: 1861 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG 1920 Query: 1921 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1977 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH Sbjct: 1921 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1977 >gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo sapiens] Length = 1975 Score = 3927 bits (10185), Expect = 0.0 Identities = 1975/1977 (99%), Positives = 1975/1977 (99%), Gaps = 2/1977 (0%) Query: 1 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE 60 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE Sbjct: 1 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE 60 Query: 61 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN 120 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN Sbjct: 61 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN 120 Query: 121 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL 180 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL Sbjct: 121 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL 180 Query: 181 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD 240 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD Sbjct: 181 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD 240 Query: 241 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP 300 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP Sbjct: 241 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP 300 Query: 301 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 360 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL Sbjct: 301 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 360 Query: 361 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 420 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV Sbjct: 361 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 420 Query: 421 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 480 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK Sbjct: 421 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 480 Query: 481 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 540 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR Sbjct: 481 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 540 Query: 541 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 600 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD Sbjct: 541 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 600 Query: 601 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 660 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP Sbjct: 601 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 660 Query: 661 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA 720 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA Sbjct: 661 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA 720 Query: 721 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL 780 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL Sbjct: 721 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL 780 Query: 781 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 840 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL Sbjct: 781 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 840 Query: 841 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF 900 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF Sbjct: 841 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF 900 Query: 901 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV 960 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV Sbjct: 901 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV 960 Query: 961 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER 1020 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER Sbjct: 961 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER 1020 Query: 1021 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE 1080 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE Sbjct: 1021 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE 1080 Query: 1081 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN 1140 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN Sbjct: 1081 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN 1140 Query: 1141 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT 1200 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT Sbjct: 1141 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT 1200 Query: 1201 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT 1260 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT Sbjct: 1201 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT 1260 Query: 1261 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT 1320 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT Sbjct: 1261 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT 1320 Query: 1321 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC 1380 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC Sbjct: 1321 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC 1380 Query: 1381 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS 1440 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS Sbjct: 1381 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS 1440 Query: 1441 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW 1500 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW Sbjct: 1441 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW 1500 Query: 1501 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA 1560 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA Sbjct: 1501 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA 1560 Query: 1561 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA 1620 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA Sbjct: 1561 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA 1620 Query: 1621 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE 1680 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE Sbjct: 1621 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE 1680 Query: 1681 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL 1740 ERSPAKRGRKSATVKP VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL Sbjct: 1681 ERSPAKRGRKSATVKP--VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL 1738 Query: 1741 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ 1800 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ Sbjct: 1739 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ 1798 Query: 1801 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE 1860 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE Sbjct: 1799 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE 1858 Query: 1861 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG 1920 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG Sbjct: 1859 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG 1918 Query: 1921 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1977 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH Sbjct: 1919 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1975 >gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo sapiens] Length = 1972 Score = 3925 bits (10180), Expect = 0.0 Identities = 1972/1972 (100%), Positives = 1972/1972 (100%) Query: 6 MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 65 MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD Sbjct: 1 MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 60 Query: 66 VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 125 VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV Sbjct: 61 VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 120 Query: 126 LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 185 LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD Sbjct: 121 LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 180 Query: 186 VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 245 VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA Sbjct: 181 VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 240 Query: 246 QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 305 QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL Sbjct: 241 QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 300 Query: 306 STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 365 STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS Sbjct: 301 STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 360 Query: 366 DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 425 DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP Sbjct: 361 DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 420 Query: 426 PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 485 PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM Sbjct: 421 PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 480 Query: 486 HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 545 HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG Sbjct: 481 HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 540 Query: 546 ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 605 ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL Sbjct: 541 ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 600 Query: 606 ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 665 ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS Sbjct: 601 ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 660 Query: 666 GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 725 GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET Sbjct: 661 GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 720 Query: 726 SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 785 SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK Sbjct: 721 SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 780 Query: 786 CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 845 CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA Sbjct: 781 CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 840 Query: 846 DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 905 DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS Sbjct: 841 DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 900 Query: 906 ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 965 ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM Sbjct: 901 ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 960 Query: 966 VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1025 VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST Sbjct: 961 VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1020 Query: 1026 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1085 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD Sbjct: 1021 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1080 Query: 1086 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1145 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS Sbjct: 1081 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1140 Query: 1146 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1205 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER Sbjct: 1141 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1200 Query: 1206 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1265 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV Sbjct: 1201 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1260 Query: 1266 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1325 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS Sbjct: 1261 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1320 Query: 1326 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1385 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD Sbjct: 1321 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1380 Query: 1386 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1445 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV Sbjct: 1381 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1440 Query: 1446 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1505 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY Sbjct: 1441 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1500 Query: 1506 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1565 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG Sbjct: 1501 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1560 Query: 1566 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1625 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD Sbjct: 1561 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1620 Query: 1626 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1685 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA Sbjct: 1621 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1680 Query: 1686 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1745 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT Sbjct: 1681 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1740 Query: 1746 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1805 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY Sbjct: 1741 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1800 Query: 1806 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1865 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL Sbjct: 1801 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1860 Query: 1866 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1925 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV Sbjct: 1861 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1920 Query: 1926 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1977 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH Sbjct: 1921 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1972 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 73.6 bits (179), Expect = 2e-12 Identities = 151/837 (18%), Positives = 288/837 (34%), Gaps = 56/837 (6%) Query: 65 DVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSS 124 D S + + G+GN+G +++ K + DSS+ D+ S + + + S Sbjct: 514 DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN-------SSDSSDS 566 Query: 125 VLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQ 184 S +S + + + + + + S N++ S + D++ S + S S Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS------DSSDSS 620 Query: 185 DVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVT 244 D + ++ E D S ++S + SD N+ S+ ++ S + Sbjct: 621 DSKSDSSKSESDSSDSDS-KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679 Query: 245 AQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEV 304 + S + + + SE S + + ++ + ++ S + Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739 Query: 305 LSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL-STN 363 S D D SN + SSD + + + S S+ ++ S S DS S+N Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799 Query: 364 SSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELE 423 SSD S + S SS + D+S S+ G + Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD---SSDSSDGSDSDSS 856 Query: 424 NPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDG 483 N S+ S +S + S S ++ S D S S + S+D Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDS----NESSNSSDSSDSSNSSDSDSSDSSNSS 912 Query: 484 DMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDE 543 D SS + + S++S ++ D S + DS +S+ S S + S Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSD--SSNSSDSS----DSSDSSNSSDSSNSSDSSNSS 966 Query: 544 DGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 603 D ++ D+ S NS +DS + + D S + D + D+ D S Sbjct: 967 DSSDSNSSDSSDSS---NSSDSSDSSDSSDSSDSSDSS-NSSDSSDSSDSSDSSNSSDSS 1022 Query: 604 ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 663 + + + + D + DS + S ++ S S D ++ + + + Sbjct: 1023 NSSDSSNSSDSSDSSD-----SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSDS 1075 Query: 664 SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEV 723 S S+ E ++ S + + + S S + S + S++ + Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135 Query: 724 ETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGV 783 S S DS D ++ + + S DSS D + S D S Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS----DSSDSSNSSDSS------- 1184 Query: 784 EKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLV 843 SDS D + + + + D+ + D + ++ + + S S Sbjct: 1185 -DSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241 Query: 844 RADDPLRLDQELQQPQTQEKTSNSLTE---DSKMANAKQLSSDAEAQKLGKPSAHAS 897 + D + + TS+S E SK N SD+++ G S H++ Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298 Score = 64.7 bits (156), Expect = 9e-10 Identities = 148/854 (17%), Positives = 284/854 (33%), Gaps = 41/854 (4%) Query: 68 SNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLG 127 S+ + +E G GN G + + + + N+ T G + IE Q + + +G Sbjct: 382 SSGNRNITKEVGKGNEGKEDKGQHGMI---LGKGNVKTQGEVVN-IEGPGQKSEPGNKVG 437 Query: 128 MSVESAPAVEE-----EKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQ 182 S + + + + ++ Q + D S + D SS G + Sbjct: 438 HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497 Query: 183 SQDVEE--NTVPYEVDKEQLQSVTTNS-----GYTRLSDVDANTAIKHEEQSNEDIPIAE 235 S+D ++ E D S T NS G D D + + K + S++ Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557 Query: 236 QSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ 295 +S D + S D + + S D S + + ++ + + +S Sbjct: 558 SNSSD----SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613 Query: 296 IQKSPEPEVLS----TQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSG 351 S + S ++ D D +K+ SSD S+ S + S +S + + S Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673 Query: 352 QRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQ 411 S S+NSSD S D+ S+ S ++ S S Sbjct: 674 SSDSSSSSDSSNSSD----SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729 Query: 412 KKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 471 S + + +S+ S +S S S S+ S Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789 Query: 472 LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSP 531 S+D D +SS + + S +S+ + NS + S + DS S+ S Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849 Query: 532 KMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKT 591 +S SS+R D + D+ S NS +DS + + D S + D Sbjct: 850 GSDSDSSNRSDSSNSS----DSSDSSDSSNSSDSSDSSDSNESSNSSDSS-DSSNSSDSD 904 Query: 592 KGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEE 651 D +++ D + +++ + +S + S ++ S S+ D Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964 Query: 652 AMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKE 711 + + + + + S S + ++ S + + + S S + S Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024 Query: 712 MPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSP 771 S++ + S S DS D ++ + + S DSS D + S Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS----DSSDSSD 1080 Query: 772 RVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPV 831 S E + + + S S + + + D+ + D + ++ Sbjct: 1081 ----SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136 Query: 832 EQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGK 891 + +S S + D + + + +S + DS ++ SSD+ Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196 Query: 892 PSAHASQSFCESSS 905 S+ +S S S S Sbjct: 1197 DSSDSSDSSDSSDS 1210 Score = 56.2 bits (134), Expect = 3e-07 Identities = 114/671 (16%), Positives = 218/671 (32%), Gaps = 6/671 (0%) Query: 14 DSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQT 73 DS S + DS+ +S E DS S N +N SN + Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665 Query: 74 AGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVES- 132 + +S + + +D DSS+ S + + SS S S Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725 Query: 133 APAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVP 192 + + + + S N++ S + D+++S + S S D ++ Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785 Query: 193 YEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH 252 + S ++NS + S ++++ + S+ + S + S D Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845 Query: 253 VVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL-STQEDL 311 + + + + + S + ++ + + +S S + S+ D Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905 Query: 312 FDQSNKTVSSDGC-STPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAP 370 D SN + SSD S+ S E S S + + + S S S+NSSD Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965 Query: 371 SPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPE 430 S + ++ SS + D+S S+ S + + N Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS--SDSSDSSDSSDSSNSSDSSN 1023 Query: 431 STVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSL 490 S+ S +S S S S+ S S+D D SS Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083 Query: 491 TVECSKTS-EIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQ 549 + + S +S + +S + S + DS S+ + S +S S + ++ Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143 Query: 550 IEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGC 609 D+ S +S +DS + + D + +D D +D+ D + Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203 Query: 610 KGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 669 ++ + DS + S + S S D ++ + SS S Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263 Query: 670 EEIPETPCESQ 680 + E+ +S+ Sbjct: 1264 DSNDESDSQSK 1274 Score = 50.4 bits (119), Expect = 2e-05 Identities = 105/597 (17%), Positives = 198/597 (33%), Gaps = 38/597 (6%) Query: 7 DPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDV 66 D + S S+ + D+ DS S + S S S + + + D Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770 Query: 67 VSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVL 126 + + + D N N +D DSSN + S + + SS Sbjct: 771 SDSSDSSDSSNSSDSNDSSNS-------SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 127 GMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDV 186 S S+ + + + + + + G+ + S D+++S + S S D Sbjct: 824 SDSSNSSDSSDSSNSSD----SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879 Query: 187 EENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQ 246 +++ E S ++NS + SD +N++ + ++ D + SS Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSD-SSNSSDSSDSSNSSDSSESSNSS-------- 930 Query: 247 PSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLS 306 N + S + S +S ++ + S+ S S + S Sbjct: 931 ----------DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980 Query: 307 TQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSD 366 D D S+ + SSD + + + S S+ ++ S S DS ++ S Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040 Query: 367 LVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPP 426 + S D+ S+ S ++ D D+S S+ +S + + N Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSS-----ESSDSSDSSNSS 1094 Query: 427 LLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMH 486 +S+ S +S S S S S S+D + D Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154 Query: 487 SSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGE 546 SS + + S +S+ + D S + DS S+ S +S S + + Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDS--SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212 Query: 547 NTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 603 ++ D+ S +S +DS + + D +D D T +D S Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269 Score = 43.1 bits (100), Expect = 0.003 Identities = 68/432 (15%), Positives = 145/432 (33%), Gaps = 10/432 (2%) Query: 477 NDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESL 536 ND G S S + S +S + D S + S S S+ S S +S Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596 Query: 537 SSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDT 596 S + +++ D+ S +SK ++++S + D + + S + D D + Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES----DSSDSDSK-SDSSDSNSSDSS 651 Query: 597 DTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIK 656 D D + ++ + DS + + S ++ S S D ++ + Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711 Query: 657 EHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMP-KK 715 + S+ + + +S ++ +S S + S + Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771 Query: 716 ECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDV 775 + S++ + S S DS D + + + S DSS D + Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS----DSDSSNSSDSS 827 Query: 776 SCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDS 835 + SDS D + + + NR D+ D + + ++ + + Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887 Query: 836 SQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAH 895 S S + + D + S++ ++ S+ +N+ S+ +++ S Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947 Query: 896 ASQSFCESSSET 907 + S SS + Sbjct: 948 SDSSNSSDSSNS 959 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 71.2 bits (173), Expect = 9e-12 Identities = 285/1408 (20%), Positives = 465/1408 (33%), Gaps = 221/1408 (15%) Query: 147 KEKEKEEDTSGNTT-HSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTT 205 + + E TS +TT EDT+S G DV +T E + V+T Sbjct: 114 ESRTTSESTSDSTTLFPSSTEDTSSPTTPEGT-------DVPMSTPSEESISSTMAFVST 166 Query: 206 N-----SGYTRLS-DVDANTAIKHEEQSNED--------IPIAEQSSKDIPVTAQPSKDV 251 YT L+ VD +T + Q++ IP + S P+T+ P+ + Sbjct: 167 APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTM 226 Query: 252 HVVKEQ-----NPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESG----------LQI 296 V + P S + S +AS + A+ + G + + Sbjct: 227 KVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVML 286 Query: 297 QKSPEPEVLSTQEDLF--------DQSNKTVSSDGCSTPSRE--EGGCSLASTPATTLHL 346 S E LST + S+ +++G S P+ EG L STPA+T+ + Sbjct: 287 VVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPV 346 Query: 347 LQLS-GQRSLVQDSLSTNSSDLVAPS--PDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLS 403 S+ ST + PS P +T + + + P+ T +++ Sbjct: 347 ATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVA 406 Query: 404 EEGGE-----PFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQ 458 P K E + P E T S STP STP+ S+P+ + Sbjct: 407 SSEASTTSTIPVDSKTFVTTASEASSSPTTAEDT-SIATSTPSEGSTPL---TSMPVSTT 462 Query: 459 PQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC 518 P S + S + + + SS T E + P ++P + LT S Sbjct: 463 PVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSM----PTSTPSEGSTPLTSMSV 518 Query: 519 KLM-LSTSEYS---------QSPKMESLSSHRIDEDGENTQIEDTEPMS--------PVL 560 M +++SE S +P S + E T I + P PV Sbjct: 519 STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578 Query: 561 NSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDV 620 V +E + PA + ++ + T + + + T T + Sbjct: 579 TRLVVSSEASTTSTTPADSNTFVTTSSE----ASSSSTTAEGTSMPTSTYSERGTTITSM 634 Query: 621 CIDLTCDSGSQAVP---------SPATRSEALSSVLDQEEAMEIKEHHPEEGS------- 664 + T + S+A +P T S +S E + EGS Sbjct: 635 SVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMP 694 Query: 665 ------SGSEVEEIPETPCESQGEELKEENMESVPLHLS----LTETQSQGLCLQKEMPK 714 + SE + TP ++ S P T T S+G MP Sbjct: 695 VNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV 754 Query: 715 KE----CSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS 770 + SEA + T+ + + + + + T+E +S+ I E S Sbjct: 755 SKTLLTSSEASTLSTTPLDTST---------HITTSTEASCSPTTTEGTSMPISTPSEGS 805 Query: 771 P---RVDVSCEPLEGVEKCS------DSQSWEDIAPEIEPCAENRLDTKEEKSVEYEG-- 819 P + VS P+ E + DS S + E+ T S EG Sbjct: 806 PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRT 865 Query: 820 DLKSGTAETEPVEQD--SSQPSLPLVRADDPLRLDQELQQPQTQEKTS-------NSLTE 870 L S T V S+ + P+ + + P T E TS T Sbjct: 866 PLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTP 925 Query: 871 DSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIP---PLTGAT 927 + M ++ +EA+ L S S+ T T EG IP P G T Sbjct: 926 LTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTT--AEGTSIPTSTPSEGTT 983 Query: 928 PPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVET-----HDPILGSGKGDSGA 982 P L P H+ ++N ST++T+ V S + + T P G + Sbjct: 984 P-----LTSTPVSHTL---VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035 Query: 983 APDVDDKLCLRMKLVSPETEASEES----LQFNLEKPATG-ERKNGSTAVAESVASPQKT 1037 P RM + + +SE S + P T + + S+ A+ + P T Sbjct: 1036 TPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST 1095 Query: 1038 MS-----VLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQ 1092 S + S R + + TTP+ ++ S++ EG T + Sbjct: 1096 YSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG--TSIPTS 1153 Query: 1093 QPMKPISPVKD-------------------PVSPASQKMVIQGPSSPQGEAMVTDVLEDQ 1133 P + +P+ PV +Q SSP A VT + Sbjct: 1154 PPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTST 1213 Query: 1134 KEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQN 1193 RST + S + T P T SA T + E GTS + + Sbjct: 1214 PGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE-GTS-LPTS 1271 Query: 1194 FGKQDATVQTERGSGEKPVSAPGD--------DTESLHSQGEEEFDMPQPPHGHVLHRHM 1245 + +T+ T V++P DT+ E P P G + Sbjct: 1272 TTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSM--PT 1329 Query: 1246 RTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLG 1305 T E RT +T + + V + + T + E SP+ + G+S Sbjct: 1330 STYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTS---- 1385 Query: 1306 DISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPAD----------FA 1355 + + + + TS S + + SS +S A P+ T GT A+ + Sbjct: 1386 -MPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGIS 1444 Query: 1356 LPSSRGGPGKLSPRKGVSQTGTPVCEED 1383 +P+S GK +P K + + TPV + Sbjct: 1445 IPTSTPSEGK-TPLKSIPVSNTPVANSE 1471 Score = 65.5 bits (158), Expect = 5e-10 Identities = 260/1256 (20%), Positives = 418/1256 (33%), Gaps = 205/1256 (16%) Query: 187 EENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQ 246 E ++ P + + + + G T L+ + +T + ++N S + + + Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196 Query: 247 PSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLS 306 S PP A MP S E L++ + + + S E LS Sbjct: 1197 ASSP--------PPTAEVTSMPTSTPG-----ERSTPLTSMPVRHTPVA---SSEASTLS 1240 Query: 307 TQEDLFDQSNK-TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 365 T D S T S++ S+P+ EG S P +T + + S + S+ +++ Sbjct: 1241 TSP--VDTSTPVTTSAETSSSPTTAEG----TSLPTST------TSEGSTLLTSIPVSTT 1288 Query: 366 DLVAPSPDAFRSTPFI----------VPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQ 415 + +P +TP V SSPT EG M TS SE G P Sbjct: 1289 LVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTS---MPTSTYSE-GRTPL----- 1339 Query: 416 SGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQ 475 + PV N L+ S +S ++TP+ STPV S S P S +P Sbjct: 1340 TSIPV---NTTLVASSAISILSTTPVDNSTPV--TTSTEACSSPTTSEGTSMP------- 1387 Query: 476 SNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG-DSCKLMLSTSEYSQSPKME 534 N +G +S+ V + P S E LS T D+ +++E + SP Sbjct: 1388 -NSNPSEGTTPLTSIPVSTT------PVVSSEASTLSATPVDTSTPGTTSAEATSSP--- 1437 Query: 535 SLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGD 594 E I + P K +P N + N + + Sbjct: 1438 --------TTAEGISIPTSTPSEGKTPLKSIPVSNTPV-------------ANSEASTLS 1476 Query: 595 DTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAME 654 T + ++ + T AE I A+ +P+ S AL+S+ + Sbjct: 1477 TTPVDSNSPVVTSTAVSSSPTPAEGTSI---------AISTPSEGSTALTSIPVSTTTV- 1526 Query: 655 IKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPK 714 + SE+ + TP + S P T + G +Q Sbjct: 1527 ----------ASSEINSLSTTPAVTSTPVTTYSQASSSP-------TTADGTSMQTSTYS 1569 Query: 715 KECSEAMEVETSVISIDSPQKLAILDQELEHKEQ-----EAWEEATSEDSSVVIVDVKEP 769 + + + S + + S + + ++ K Q EA T+E SS+ I E Sbjct: 1570 EGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG 1629 Query: 770 SP---RVDVSCEPLEGVEKCS------DSQSWEDIAPEIEPCAENRLDTKEEKSVEYEG- 819 SP + VS P+ E + DS S + E+ T S EG Sbjct: 1630 SPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR 1689 Query: 820 -DLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAK 878 L S T T PV S+ +L D+ + T+ ++S + +E + M N+ Sbjct: 1690 TPLTSITVRTTPV-ASSAISTLSTTPVDNSTPV-----TTSTEARSSPTTSEGTSMPNST 1743 Query: 879 QLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLP-------------KEGDIIPPLT- 924 + + S + S TP + P EG IP T Sbjct: 1744 PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTL 1803 Query: 925 --GATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGS---GKGD 979 G TP L P H+ ++N ST++T+ V S S V T + S +G Sbjct: 1804 SEGMTP-----LTSTPVSHTL---VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1855 Query: 980 S-GAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTM 1038 S + + L VS T AS E+ + T V+ S + + Sbjct: 1856 SIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSS 1915 Query: 1039 SVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHT--IRQSQQPMK 1096 S E R PP T I + SS+ L T SQ Sbjct: 1916 MPTSTPREGR---------PPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSS 1966 Query: 1097 PISPVKDPV-SPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQ- 1154 P + + +PA + S P +V + P+ E S Sbjct: 1967 PTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSP 2026 Query: 1155 ---NNIGIQTMECSLRVPETVSAATQTIKNVCEQG----TSTVDQNFGKQDATVQTERGS 1207 IQT S R T V +G T+ VD ++T + + Sbjct: 2027 TTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSAT 2086 Query: 1208 GE---KPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYY 1264 E +SAP + + L S + P + + + V T T V + Sbjct: 2087 AEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT-STEVSSSPIP 2145 Query: 1265 VDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDIS---SFSSKASSLHRTS 1321 +GT ++ + P+ T V+ S S D S + S++A S TS Sbjct: 2146 TEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS 2205 Query: 1322 SGTSL-SAMHSSGSSGKGAGPL--------RGKTSGTEPADFALPSSRGGPGKLSP 1368 GTS+ ++ S GS+ + P+ T P D + P + SP Sbjct: 2206 EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSP 2261 Score = 53.5 bits (127), Expect = 2e-06 Identities = 322/1730 (18%), Positives = 547/1730 (31%), Gaps = 185/1730 (10%) Query: 53 PNLQTHKENPV---LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSI 109 P T PV V+++ E ++ +G S E + P+ S + T Sbjct: 1646 PEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRT--PLTSITVRTTPVA 1703 Query: 110 SQVIEQL---PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTS--GNTTHSLG 164 S I L P N T S+P E + TS +TT L Sbjct: 1704 SSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLS 1763 Query: 165 AEDTASSQLGFGVLELSQ--SQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVD-ANTAI 221 +E +S L ++ S + E + P + + + T + G T L+ ++T + Sbjct: 1764 SE---ASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLV 1820 Query: 222 KHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAK 281 + E S + +S + TA S +P PA + S + + Sbjct: 1821 ANSEASTLSTTPVDSNSPVVTSTAVSS---------SPTPAEGTSIATSTPSEGSTALTS 1871 Query: 282 EQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQ-SNKTVSSDGCSTPSR--EEGGCSLAS 338 +S + S S P V ST + Q S+ ++DG S P+ EG L S Sbjct: 1872 IPVSTTTVASSETNTL-STTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTS 1930 Query: 339 TPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMD 398 P +T + S + + + +L+ + + S + T S PT P+ Sbjct: 1931 IPVSTTTVA--SSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLT 1988 Query: 399 TSVLSEEGGEPFQKKLQSGEPVELENPPLLP-ESTVSP--------QASTPISQSTPV-- 447 + LS + S PV+ P E + SP Q STP ++TP+ Sbjct: 1989 SMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG 2048 Query: 448 FPPGS-LPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSE------- 499 P + L + S+ + S + S + SS+T+ Sbjct: 2049 MPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIP 2108 Query: 500 --IEPKNSPEDLGLSLTG-DSCKLMLSTSEYSQSP-KMESLSSHRIDEDGENTQIEDTEP 555 P SPE LS T DS +++++E S SP E S T + Sbjct: 2109 LSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPV 2168 Query: 556 MSPVLNSKFV------------PAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 603 + V+ S + P N + + E ++G T +S Sbjct: 2169 STTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS 2228 Query: 604 ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 663 + A V + ++A SP T E P Sbjct: 2229 TMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288 Query: 664 S--SGSEVEEIPETPCESQGEELKEENMESVPLHLS----LTETQSQGLCLQKEMPKKEC 717 + + SEV + TP +S S P T T S+G MP Sbjct: 2289 TLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348 Query: 718 SEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSC 777 A ETS +S A + Q T++D+S+ E S ++ Sbjct: 2349 MVA-SFETSTLSTTP----ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGS--TPLTS 2401 Query: 778 EPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAE------TEPV 831 P+ + S S P +DT + E TAE + P Sbjct: 2402 VPVSTMPVVSSEASTHSTTP---------VDTSTPVTTSTEASSSPTTAEGTSIPTSPPS 2452 Query: 832 EQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGK 891 E + S+P+ + P+ + T TS +T ++ + SS A+ + Sbjct: 2453 EGTTPLASMPV--STTPVVSSEAGTLSTTPVDTSTPMTTSTEAS-----SSPTTAEDIVV 2505 Query: 892 PSAHASQ--SFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISN 949 P + AS+ + S + P+ + + P++ ++ +T ++ Sbjct: 2506 PISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSS--ATSAEGTS 2563 Query: 950 YPESTIATSDVMSESMVETHDPILGSGKGDSGAAP-DVDDKLCLRMKLVSPETEASEESL 1008 P ST + SM + P+ S P D + + S T A + S+ Sbjct: 2564 MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623 Query: 1009 QFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNL- 1067 + + + + +S T+S + PTT ++ Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683 Query: 1068 LHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVT 1127 P + L + S+ +PV + P++ +G +M Sbjct: 2684 TSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRI 2743 Query: 1128 DVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVS---AATQTIKNVCE 1184 D ST + + + S + T +P T S +++ T V Sbjct: 2744 STPSDG----STPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTS 2799 Query: 1185 QGTSTVDQNFGKQDATVQTERGSGEKPV--------SAPGDDTESLHSQGEEEFDMPQPP 1236 TST + +T T PV S DT + + + P Sbjct: 2800 MPTSTPSET-----STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854 Query: 1237 HGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQ 1296 G V+ + T E TL+T + V +E T + I E SP+ Sbjct: 2855 EGIVVP--ISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTT 2912 Query: 1297 TGGSSGDLGDISSFSSKASSLHRTS---SGTSLSAMHSSGSSGKG--AGPLRGKTSGTEP 1351 G+S + S S+ +S+ ++ +G+ S + ++ + +S T Sbjct: 2913 AEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTA 2972 Query: 1352 ADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPS 1411 ++P S G + +P +S + PV + PVT S Sbjct: 2973 EGTSMPISTPGE-RRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA-----SS 3026 Query: 1412 RTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPD-STRRTDVGAGALRRSDSPEI 1470 T T +P E +P S + +P ST D S+SP + Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD--------SNSPVV 3078 Query: 1471 -PFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYE 1529 + ++ P+ S P +++ G L Sbjct: 3079 TSTEVSSSPTPAEGTSMPISTY------------------------SEGSTPLTGVPVST 3114 Query: 1530 CDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRK-WYKR 1588 V I P+DT + E S+ E + S EG Y Sbjct: 3115 TPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTT----SEGTSMPTSTPSEGSTPLTYMP 3170 Query: 1589 MAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASS 1648 ++ +L + + P + TP+T + + + EG S S TP S Sbjct: 3171 VSTMLVVSSED---STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSV 3227 Query: 1649 SSSTTPTRKITESPRASMGVLSGKRKLITSEEERS--PAKRGRKSATVKP 1696 S TP +E+ S + L TS E S P G T P Sbjct: 3228 PVSNTPVAS-SEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP 3276 Score = 45.4 bits (106), Expect = 5e-04 Identities = 226/1130 (20%), Positives = 371/1130 (32%), Gaps = 130/1130 (11%) Query: 97 PVDSSNLDTCGSISQVIEQLPQPNRTSSVLG--MSVESAPAVEEEKGEELEQKEKEKEED 154 PVD+S L T S LP +S+L +S S P L + Sbjct: 358 PVDTSTLVTT---STEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTS 414 Query: 155 TS--GNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRL 212 T + T A + +SS ++ S E +T + ++ + Sbjct: 415 TIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLST 474 Query: 213 SDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFS-- 270 + VD+ T + +++ P AE +S ++ S + + P A SE S Sbjct: 475 TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTT 534 Query: 271 PKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSRE 330 P + + + S+ G I S E + ++ + VSS+ +T + Sbjct: 535 PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594 Query: 331 EGG------CSLASTPATTLHLLQLS----GQRSLVQDSLSTNSSDLVAPSPDAFRSTPF 380 S AS+ +TT + +R S+S S+ LVA S + ST Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSV-STTLVASSEASTLSTTP 653 Query: 381 IVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELE--NPPLLPESTVSPQAS 438 + ++P + +S +E P + P+ N L+ S S ++ Sbjct: 654 VDSNTPVTTS---TEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST 710 Query: 439 TPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTS 498 TP+ STPV S S P + +P+ + E S M S + S+ S Sbjct: 711 TPVDTSTPV--TTSTEASSSPTTADGASMPTSTPSEGSTPLT---SMPVSKTLLTSSEAS 765 Query: 499 EIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMS- 557 + +P D +T +++E S SP +S I E + + + P+S Sbjct: 766 TL--STTPLDTSTHIT--------TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSI 815 Query: 558 -PVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 616 PV + + + N ++S + +G T +T +GR Sbjct: 816 TPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPT-------STYSEGRTPLT 868 Query: 617 AEDVCIDLTCDSGSQAV-------PSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 669 + V L S + +P T S S E + P EGS+ Sbjct: 869 SMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTS 928 Query: 670 EEIPETP-CESQGEELKEENME-SVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSV 727 TP S+ L ++ S P+ S T S +P SE Sbjct: 929 MPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEG------- 981 Query: 728 ISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCS 787 +P + L + + T DS+ + E S + EG + Sbjct: 982 ---TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA----EGTSMPT 1034 Query: 788 DSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADD 847 + S E P + E S L + A+T SQ S AD Sbjct: 1035 STPS-EGSTPLTRMPVSTTMVASSETST-----LSTTPADTSTPVTTYSQASSSSTTADG 1088 Query: 848 ---PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESS 904 P E P T S L S+ + D A +S + E + Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148 Query: 905 SETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSES 964 S +P PP G TP L ST + +S+ +T++T+ V S++ Sbjct: 1149 S-------IPTS----PPSEGTTP-------LASMPVSTTLVVSS-EANTLSTTPVDSKT 1189 Query: 965 MVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGS 1024 V T ++ + P + + P + E S P T Sbjct: 1190 QVAT--------STEASSPPPTAEVTSM------PTSTPGERS------TPLTSMPVR-H 1228 Query: 1025 TAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEG 1084 T VA S AS T+S A + PTT +L +S+G + Sbjct: 1229 TPVASSEAS---TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPV 1285 Query: 1085 DHTIRQSQQPMKPISPVKDPVSP-ASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKEN 1143 T+ S + ++ D P + V P+ +G +M T EGR+ Sbjct: 1286 STTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTST---YSEGRTPLTSI 1342 Query: 1144 PSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQN 1193 P + S +I + T P T S + E GTS + N Sbjct: 1343 PVNTTLVASSAISI-LSTTPVDNSTPVTTSTEACSSPTTSE-GTSMPNSN 1390 Score = 41.6 bits (96), Expect = 0.008 Identities = 96/479 (20%), Positives = 173/479 (36%), Gaps = 51/479 (10%) Query: 154 DTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYT-RL 212 DTS T S A + ++ G + S S E T P V ++ T Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPS----EGTTPLASMPVSTTPVVSSEVNTLST 3421 Query: 213 SDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK 272 + VD+NT + +++ IAE +S T++ S + ++ P A SE + Sbjct: 3422 TPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSE----AST 3477 Query: 273 ASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEG 332 S ++ ++ S + + E +N VS +TP Sbjct: 3478 LSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS----TTPVASSE 3533 Query: 333 GCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIV---------P 383 +L++TP + + S Q S +L + + PS + T ++ Sbjct: 3534 ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEA 3593 Query: 384 SSPTEQEGRQDKPMDTSVLSEEGGEPFQK-KLQSGEPVELENP-PLLPESTVS------- 434 S+P+ + P+ TS S P + L P E+ P ++P ST S Sbjct: 3594 STPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAG 3653 Query: 435 PQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVEC 494 ++ P+ STPV S + S P +P + E S M S+ V Sbjct: 3654 TASTLPVDTSTPVIT--STQVSSSPVTPEGTTMPIWTPSEGSTPLT---TMPVSTTRVTS 3708 Query: 495 SKTSEIEP----KNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQI 550 S+ S + ++P S L +T S ++ +L + T + Sbjct: 3709 SEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGT---------TIL 3759 Query: 551 EDTEPMS--PVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILAT 607 T P++ P ++ +P+ S+ M A +G + + T + T + ++L T Sbjct: 3760 VSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTT 3818 Score = 34.7 bits (78), Expect = 0.95 Identities = 99/481 (20%), Positives = 167/481 (34%), Gaps = 82/481 (17%) Query: 57 THKENPVLDVVSNPEQTAGEERGDGNSGF-NEHLKENKVAD---------PVDSSNLDTC 106 T+ +V S P TAGE G++ N + VA PVDS+ T Sbjct: 3495 TNSSPTTAEVTSMPTSTAGE----GSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTS 3550 Query: 107 GS--------ISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGN 158 S + ++ P+ SS L + S+ V + D S Sbjct: 3551 SSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST----PSTPSVDRSTP 3606 Query: 159 TTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVT-TNSGYTRLSDVDA 217 T S + T + V+ L S E +T P + SVT + +G VD Sbjct: 3607 VTTSTQSNSTPTPP---EVITLPMSTPSEVST-PLTIMPVSTTSVTISEAGTASTLPVDT 3662 Query: 218 NTAIKHEEQSNED--------IPIAEQSSKDIPVTAQPSKDVHVVKEQN----------- 258 +T + Q + +PI S P+T P V + Sbjct: 3663 STPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTS 3722 Query: 259 -PPPARSEDMPFSPKASVAAMEAKEQLSAQEL----MESGLQIQKSPEPEVLSTQEDLFD 313 P +E + S M + L + S + + PE S ++ Sbjct: 3723 TPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPS-VYT 3781 Query: 314 QSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPD 373 + T +S+G S+P+ EG TT + + +RS + ++ + +++PS Sbjct: 3782 SMSMTTASEGSSSPTTLEG---------TTTMPMSTTSERSTLLTTVLISPISVMSPSEA 3832 Query: 374 AFRSTPFIVPSSP---TEQEGRQDKPMDTSV----LSEEGGEPFQKKLQS--------GE 418 + STP S+P + + G P + + ++ E P L S G Sbjct: 3833 STLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892 Query: 419 PVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQF-SHDIFIPSPSLEEQSN 477 + PPL +T +P T + + PV S+ + ++ IFIPS + + Sbjct: 3893 SI-ASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTA 3951 Query: 478 D 478 D Sbjct: 3952 D 3952 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 67.8 bits (164), Expect = 1e-10 Identities = 140/658 (21%), Positives = 253/658 (38%), Gaps = 85/658 (12%) Query: 233 IAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSA-QELME 291 I +S + I V + K+ +V+EQ +E++ + E KE+ +E E Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE 495 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSG 351 G + KSP E ++ E +P +EE A +PA S Sbjct: 496 GGEEETKSPPAEEAASPE------------KEAKSPVKEE-----AKSPAEA-----KSP 533 Query: 352 QRSLVQDSLSTNSSDLV-APSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPF 410 ++ + S + +P+ + +S P SP ++E + + + E+ P Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSPEKEEAKSPAEVKS---PEKAKSPA 588 Query: 411 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIP-SQPQFSHDIFIPS 469 +++ +S P E ++P +S V +A +P +PV P P+ + S Sbjct: 589 KEEAKS--PAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA-----KS 640 Query: 470 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQ 529 P+ EE + K + + E +K+ SPE + ++ + S + Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE 700 Query: 530 SPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDD 589 K + + E+ ++ + + SPV P + S + A+ E S Sbjct: 701 EAKSPEKAKSPVKEEAKSPE----KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756 Query: 590 KTKGDDTDTRDDISILATGCKGREETVA-EDVCIDLTCDSGSQAVPSPATRSEALSSVLD 648 KT D+ +EE + D + + V SP +A S + + Sbjct: 757 KTL--------DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP---EKAKSPLKE 805 Query: 649 QEEAMEIKEHHPEEGSSGSEVEEIP-ETPCESQGEELKEENMESVPLHLSLTETQSQGLC 707 +A E + EE S + EE P E + ++ +EE + P +T+ + Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP------KTEEKKDS 859 Query: 708 LQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVK 767 ++E PKKE + E +++ P+ + ++E K++EA ED V K Sbjct: 860 KKEEAPKKEAPKPKVEEKKEPAVEKPK-----ESKVEAKKEEA------EDKKKVPTPEK 908 Query: 768 EPSPRVDV--SCEPLEGVE----KCSDSQSWEDIAP-EIEPCAENRLDTKEEKSVEYEGD 820 E +V+V +P E E + D+++ E P E + A + DTKEEK+ + E Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968 Query: 821 LKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAK 878 K+ E + S +PS P + ++ Q K TED K A K Sbjct: 969 PKTEAKAKEDDKTLSKEPSKPKAE-----KAEKSSSTDQKDSKPPEKATED-KAAKGK 1020 Score = 65.9 bits (159), Expect = 4e-10 Identities = 136/665 (20%), Positives = 252/665 (37%), Gaps = 84/665 (12%) Query: 513 LTGDSCKLMLSTSEYSQS---PKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAEN 569 L G+ C++ +S PK+ S+S+H +++ E + V S E Sbjct: 406 LEGEECRIGFGPIPFSLPEGLPKIPSVSTH--------IKVKSEEKIKVVEKS-----EK 452 Query: 570 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 629 +++++ Q E Q+++ + T+ ++ + +++ +G+EE E+ + G Sbjct: 453 ETVIVEE-QTEETQVTE--EVTEEEEKEAKEE--------EGKEEEGGEEE----EAEGG 497 Query: 630 SQAVPSP------ATRSEALSSVLDQEEA-MEIKEHHPEEGSSGSEVEEIPETPCESQGE 682 + SP + EA S V ++ ++ E K EE S +EV+ PE E Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS-PEKAKSPAKE 556 Query: 683 ELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQE 742 E K P E + + + P+K S A E S SP+K +E Sbjct: 557 EAKS------PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610 Query: 743 LEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPC 802 EA E S +VK P + E + EK + E +PE Sbjct: 611 EAKSPAEAKSPVKEEAKSPA--EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668 Query: 803 ---AENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQP- 858 AE + K + V+ E KS PV++++ P + + ++ + P Sbjct: 669 PVKAEAKSPEKAKSPVKAEA--KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726 Query: 859 ----QTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAH--ASQSFCESSSETPFHFT 912 +T EK + + E++K + A+ + P A A + + + P Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786 Query: 913 LPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPI 972 P + ++ P +P LK + K I +S + + E V+ +P Sbjct: 787 SPVKEEVKSPEKAKSP-----LKEDAKAPEKEIPKKEEVKSPVKEEEKPQE--VKVKEPP 839 Query: 973 LGSGKGDSGAAPDVDDKLCLRMKLVSPETEAS----EESLQFNLEKPATG--ERKNGSTA 1026 + + + A P ++K + K +P+ EA EE + +EKP E K Sbjct: 840 KKAEEEKAPATPKTEEKKDSK-KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898 Query: 1027 VAESVASPQKTMSVLSCICE---ARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLE 1083 + V +P+K + E +++ E ++P + PS E+++ E Sbjct: 899 DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE-----PSKPAEKKEAAPE 953 Query: 1084 GDHTIRQSQQPMKPIS-PVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKE 1142 T + ++ KP P + + K + + PS P+ E DQK+ + K Sbjct: 954 KKDT--KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011 Query: 1143 NPSKA 1147 KA Sbjct: 1012 TEDKA 1016 Score = 48.9 bits (115), Expect = 5e-05 Identities = 128/672 (19%), Positives = 245/672 (36%), Gaps = 114/672 (16%) Query: 638 TRSEALSSVLD--QEEAMEIKEHHPEEGSSGSEV-----EEIPETPCESQGEELKEENME 690 T EAL S D + + E+++ H + +S E E+ T E + + +++ Sbjct: 330 TELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLL 389 Query: 691 SVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQ---KLAILDQELEHKE 747 +V + L + + +K + +EC + I P+ K+ + ++ K Sbjct: 390 NVKMALDI-----EIAAYRKLLEGEEC----RIGFGPIPFSLPEGLPKIPSVSTHIKVKS 440 Query: 748 QEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRL 807 +E + + VIV+ E+ ++Q E++ E E A+ Sbjct: 441 EEKIKVVEKSEKETVIVE------------------EQTEETQVTEEVTEEEEKEAKEEE 482 Query: 808 DTKEEKSVEYEG-----DLKSGTAE---------TEPVEQDSSQPSLPLVRADDPLRLDQ 853 +EE E E + KS AE PV++++ P+ + + Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA 542 Query: 854 ELQQPQ---TQEKTSNSLTEDSKMANAKQLSSDAEA---QKLGKPSAHASQSFCESSS-- 905 E++ P+ + K ++K ++ S AE +K P+ ++S E+ S Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602 Query: 906 ----------ETPFHFTLPKEGDIIPPLTGATP-----PLIGHLKLEPKRHSTPIGISNY 950 ++P P + + P +P P K K S + Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS 662 Query: 951 PESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSP---ETEASEES 1007 PE + ++S + P+ K A V ++ K SP E ++ E++ Sbjct: 663 PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKA 722 Query: 1008 LQFNLEKPATGERKNGSTAVAESVASPQ--------KTMSVLSCICEARQENEARS---- 1055 E+ T E+ + V E SP+ KT+ V S + + EARS Sbjct: 723 KSPVKEEAKTPEK--AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780 Query: 1056 -EDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKP--ISPVKDPVSPASQKM 1112 + +P++ + E+ K L+ D + + P K SPVK+ P K+ Sbjct: 781 FPEKAKSPVKEEV-----KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV 835 Query: 1113 VIQGPSSPQGEAMVTDVLEDQKEGR---STNKENP-------SKALIERPSQNNIGIQTM 1162 + + +A T E++K+ + + KE P + +E+P ++ + + Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895 Query: 1163 EC----SLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAP-GD 1217 E + PE + A +K + T DA + EK +AP Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKK 955 Query: 1218 DTESLHSQGEEE 1229 DT+ ++ EE Sbjct: 956 DTKEEKAKKPEE 967 Score = 47.4 bits (111), Expect = 1e-04 Identities = 142/695 (20%), Positives = 262/695 (37%), Gaps = 138/695 (19%) Query: 113 IEQLPQPNRTSSVLGMSVESAPAVEE-EKGEELEQKEKEKEEDTSGNTTHSLGAEDTASS 171 I+ + + + + ++ E EE + EE E KE+E +E+ G + G E Sbjct: 444 IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE----- 498 Query: 172 QLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 231 E ++S EE P +KE V + S +A + K E +S ++ Sbjct: 499 -------EETKSPPAEEAASP---EKEAKSPVKEEA----KSPAEAKSPEKEEAKSPAEV 544 Query: 232 PIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELME 291 E++ P+K+ + ++PP A+S E +E S E+ Sbjct: 545 KSPEKAK-------SPAKE----EAKSPPEAKSP-------------EKEEAKSPAEV-- 578 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSG 351 KSPE +E+ + + S + +P +EE A +PA Sbjct: 579 ------KSPEKAKSPAKEEAKSPA-EAKSPEKAKSPVKEE-----AKSPAEA-------- 618 Query: 352 QRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQ 411 +S V++ S SP+ +S PT++E + + S EE P + Sbjct: 619 -KSPVKEEA---KSPAEVKSPEKAKS--------PTKEEAKSPEKA-KSPEKEEAKSPEK 665 Query: 412 KKLQSGEPVELE-NPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSP 470 K PV+ E P +S V +A +P +PV P ++ SP Sbjct: 666 AK----SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK----------SP 711 Query: 471 SLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQS 530 EE + K + + T E +K+ E SPE + + + K + S +++ Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK---AKSPEKAKTLDVKSPEAKT 768 Query: 531 PKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDD- 589 P E S D+ E + SPV P + S L A+ E ++ + ++ Sbjct: 769 PAKEEARS-PADKFPEKAK-------SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820 Query: 590 KTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQ 649 K+ + + ++ + K EE + A P + ++ + Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEK--------------APATPKTEEKKDSKKEEAPK 866 Query: 650 EEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQ 709 +EA + K +E + VE+ E+ E++ EE +++ P + + + + Sbjct: 867 KEAPKPKVEEKKEPA----VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKP 922 Query: 710 K---EMPKKECSEAMEVETSVISID---SPQKLAILDQELEHKEQEAWEEATSEDSSVVI 763 K E+ KKE +A E S + +P+K +++ + E++ EA +++ + Sbjct: 923 KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL 982 Query: 764 VDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPE 798 KEPS E EK S + + PE Sbjct: 983 --SKEPSK------PKAEKAEKSSSTDQKDSKPPE 1009 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 66.6 bits (161), Expect = 2e-10 Identities = 232/1220 (19%), Positives = 442/1220 (36%), Gaps = 229/1220 (18%) Query: 203 VTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH---VVKEQNP 259 VTT S ++ S T+ K + +D+ A + K P+ QP+ +H K + P Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT--LHGSPSAKAKQP 723 Query: 260 PPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTV 319 P A S P PK E + A + K +P+++ DL S+ T Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADD---------KPKQPKMVKPTTDLVSSSSATT 774 Query: 320 SSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP 379 D S S+ + +TP L DS + S P + +P Sbjct: 775 KPDIPS--SKVQSQAEEKTTPP-------------LKTDSAKPSQSF----PPTGEKVSP 815 Query: 380 FIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQAST 439 F + P D+ ++S G K + +PV+ + P ++ +SP+ Sbjct: 816 FDSKAIPRPAS-------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868 Query: 440 -PISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTS 498 P+ + +P PPG P Q +P+P + + + ++ S+T + K+ Sbjct: 869 KPMPKGSPT-PPGPRPTAGQT-------VPTPQQSPKPQEQSRRFSLNLGSIT-DAPKSQ 919 Query: 499 EIEPKNSPE----DLGLSLTGDSCKLMLSTSE---YSQS-PKMESLSSHRIDEDGENTQI 550 P+ + G S+ + L+ + + +SQS P + + + Sbjct: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979 Query: 551 EDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTD-----TRDDISIL 605 + +P +K +P + ++ PA + ++ K +T+ +D S+ Sbjct: 980 PKSTGQAPPAPAKSIPVKKET--KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037 Query: 606 ATGCKG------REETVAEDVC--IDLTCDSGSQAVPSPATRSEALSSVLD------QEE 651 A K + E C + GS+ P+ T +E + V + Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097 Query: 652 AMEIKEH-----HPEEGSSG--SEVEEIPETPCESQGEEL-----KEENMESVPLHLSLT 699 EI+E + SG ++ ++P P + + +VP + L Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLV 1157 Query: 700 ETQSQGLCLQKE---MPKKECSEAMEVETSVISIDSPQKLAILDQEL-----------EH 745 + Q Q + + E + K + + +ME +++ D Q+ + L+++ E Sbjct: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEE 1217 Query: 746 KEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAEN 805 K+ EE + +++ K+P+P D P E + Q + + +++ AE Sbjct: 1218 KKLIPEEEKIRSEEKKPLLEEKKPTPE-DKKLLP-EAKTSAPEEQKHDLLKSQVQ-IAEE 1274 Query: 806 RLDTKEEKSVEYEG--------DLKSGTAETEPVEQDSS------QPSLPLVRADDPLRL 851 +L+ + EG L SGT ++ P E D + QP P D + Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334 Query: 852 DQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHF 911 +E +T+++ S T S+ + Q SD + ++S S E P Sbjct: 1335 GKE----KTEKEDDKSDTSSSQQPKSPQGLSD---------TGYSSDGISSSLGEIP--- 1378 Query: 912 TLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYP--ESTIATSDVMSESMVETH 969 +IP T L G K + S+P S+ EST+ S++E Sbjct: 1379 ------SLIP--TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL-------SILEAQ 1423 Query: 970 DPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAE 1029 L K + P VSPE +E Q Sbjct: 1424 ASTLADEKSEKKTQPHE----------VSPEQPKDQEKTQ-------------------- 1453 Query: 1030 SVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIR 1089 S +T+ + E ++ E R + T + + PSS+ +EK + D T R Sbjct: 1454 ---SLSETLEITISEEEIKESQEERKD----TFKKDSQQDIPSSKDHKEKSEFVDDITTR 1506 Query: 1090 QSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALI 1149 + +P V++ + + + + G + + ++ +G ++ K +I Sbjct: 1507 R-----EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561 Query: 1150 ERPSQNNI-GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSG 1208 E + + G + E + +S++T++ K ++ GK T R Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKK---------EETKGKGKITAGKHRRLT 1612 Query: 1209 EKPVSAPGDDT---ESLHSQGEEEFD-MPQPPHGHVLHRHMRT--------IREVRTL-V 1255 K ++ +D S H + +E FD P+ + + +R +T+ + Sbjct: 1613 RKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIEL 1672 Query: 1256 TRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKAS 1315 I D Y + ++ + + + EEP +E + ++ S S G+ S S AS Sbjct: 1673 NSTIADKYSAESSQKKTSLYFD-EEPELEME----SLTDSPEDRSRGE----GSSSLHAS 1723 Query: 1316 SLHRTSSGTSLSAMHSSGSS 1335 S +S TS+S++ S Sbjct: 1724 SFTPGTSPTSVSSLDEDSDS 1743 Score = 46.2 bits (108), Expect = 3e-04 Identities = 149/724 (20%), Positives = 265/724 (36%), Gaps = 111/724 (15%) Query: 23 PCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQT-AGEERGDG 81 P + E QP++++ SG+ S+ +T KE P + P+Q G+E Sbjct: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKE---- 1337 Query: 82 NSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKG 141 K K D D+S+ S + + + SS LG P E++ Sbjct: 1338 --------KTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389 Query: 142 EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEV------ 195 + L +K+ +E + + + E T S L L+ + E+ T P+EV Sbjct: 1390 KGL-KKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPK 1447 Query: 196 DKEQLQSVTTNSGYT----RLSDVDANTAIKHEEQSNEDIPIAEQSSK------DIPVTA 245 D+E+ QS++ T + + ++ S +DIP ++ + DI Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRR 1507 Query: 246 QP--SKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ---IQKSP 300 +P S + E +P P R +S + Q S +E E ++ I+ S Sbjct: 1508 EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE--EDFIRKQIIEMSA 1565 Query: 301 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 360 + + +++D F ++ S + +EE + T +L+ + S D Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEE---TKGKGKITAGKHRRLTRKSSTSIDED 1622 Query: 361 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 420 + +AF +P E + R+ K ++ L GG L+ + + Sbjct: 1623 AGRRHSWHDEDDEAFDESP--------ELKYRETKSQESEELVVTGG----GGLRRFKTI 1670 Query: 421 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 480 EL ST++ + S SQ SL +P+ + SP E + G+ Sbjct: 1671 EL-------NSTIADKYSAESSQKKT-----SLYFDEEPELEMESLTDSP---EDRSRGE 1715 Query: 481 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 540 +H+SS T P SP + SL DS S S K + + HR Sbjct: 1716 GSSSLHASSFT----------PGTSPTSVS-SLDEDSDS---SPSHKKGESKQQRKARHR 1761 Query: 541 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 600 T IED+ + E + +L + E++ Q +K D +D Sbjct: 1762 PHGPLLPT-IEDSSEEEEL-------REEEELLKEQEKQREIEQQQRKSSSKKSKKD-KD 1812 Query: 601 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 660 ++ + R E + PS + E S + +A E++E H Sbjct: 1813 ELR-----AQRRRER--------------PKTPPSNLSPIEDASPTEELRQAAEMEELHR 1853 Query: 661 EEGSSGS-EVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE 719 S S +E PE S + ++ + + +P +SL + +QKE +K Sbjct: 1854 SSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKS 1913 Query: 720 AMEV 723 A E+ Sbjct: 1914 AEEM 1917 Score = 37.7 bits (86), Expect = 0.11 Identities = 152/794 (19%), Positives = 254/794 (31%), Gaps = 127/794 (15%) Query: 163 LGAEDTASSQLGF--GVLELSQSQDVEENTVPYEV--DKEQLQSVTTNSGYTRLSDVDAN 218 L E +S GF V LS V P+++ D E Q TT Sbjct: 144 LKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK----------Q 193 Query: 219 TAIKHEEQSNEDI---PIAEQSSKDIPVTAQPSKDV---------------HVVKEQNPP 260 ++ E+ E I P+ +Q K IP P +D +K Q P Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253 Query: 261 PARSEDMPF-SPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK-- 317 + P +P+ A + + S + ++ + +S +P + S + Q Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313 Query: 318 --------TVSSDGCSTPSREEGGCS--LASTPATTLHLLQLSGQRSLVQDSLS------ 361 S G + P + G + LA P T +Q G L Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373 Query: 362 ----TNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDT----SVLSEEGG--EPFQ 411 + P P A P V +P +Q G P L+++ G P + Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPG-VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432 Query: 412 KKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 471 + PV+ P +P P T Q+ P PP LP P++P P P+ Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKPPPQQ----PGPA 487 Query: 472 LEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---KNSPEDLGLSLTGDSCKLMLSTSEYS 528 G T K +P K SP+ G ST S Sbjct: 488 KPPPQQPGSAKPPSQQPGST----KPPPQQPGPAKPSPQQPG------------STKPPS 531 Query: 529 QSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFV--PAENDSILMNPAQ-------- 578 Q P S+ + + Q + T+P+S + K + P + S P+Q Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590 Query: 579 ---DGEVQLSQNDDKTKGDDTDTRDDI-SILATGCKGREETVAEDVCIDLTCDS--GSQA 632 E+ L + T+ + + S+ V E +C++ G Sbjct: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650 Query: 633 VPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESV 692 P P++ L + + + P+ + + + P+ E K + Sbjct: 651 APVPSSPQPKLKTA-PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709 Query: 693 P-LHLSLTETQSQ---GLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELE---- 744 P LH S + Q L K P KE S E + + ++ D P++ ++ + Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769 Query: 745 -----------HKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEG---VEKCSDSQ 790 K Q EE T+ + P P + SDS+ Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829 Query: 791 SWEDIAPEIEPCAENRLDTKEEKSVEYEGDLK-SGTAETEPVEQDSSQPSLPLVRADDPL 849 P E + ++D ++K + K S + +P+ + S P P A + Sbjct: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTV 889 Query: 850 RLDQELQQPQTQEK 863 Q+ +PQ Q + Sbjct: 890 PTPQQSPKPQEQSR 903 Score = 33.1 bits (74), Expect = 2.8 Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 4/120 (3%) Query: 1012 LEKPATGERKNGSTAVAESVASPQKTM--SVLSCICEARQENEARSEDPPTTPIRGNLLH 1069 + P+ R + + + +++P+KT L C EA + ++ T+P + Sbjct: 3534 IRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRP 3593 Query: 1070 FPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDV 1129 P G L D T++ + P K + P+SP S ++ P + + D+ Sbjct: 3594 TPLEIG--YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDI 3651 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 66.6 bits (161), Expect = 2e-10 Identities = 232/1220 (19%), Positives = 442/1220 (36%), Gaps = 229/1220 (18%) Query: 203 VTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH---VVKEQNP 259 VTT S ++ S T+ K + +D+ A + K P+ QP+ +H K + P Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT--LHGSPSAKAKQP 723 Query: 260 PPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTV 319 P A S P PK E + A + K +P+++ DL S+ T Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADD---------KPKQPKMVKPTTDLVSSSSATT 774 Query: 320 SSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP 379 D S S+ + +TP L DS + S P + +P Sbjct: 775 KPDIPS--SKVQSQAEEKTTPP-------------LKTDSAKPSQSF----PPTGEKVSP 815 Query: 380 FIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQAST 439 F + P D+ ++S G K + +PV+ + P ++ +SP+ Sbjct: 816 FDSKAIPRPAS-------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868 Query: 440 -PISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTS 498 P+ + +P PPG P Q +P+P + + + ++ S+T + K+ Sbjct: 869 KPMPKGSPT-PPGPRPTAGQT-------VPTPQQSPKPQEQSRRFSLNLGSIT-DAPKSQ 919 Query: 499 EIEPKNSPE----DLGLSLTGDSCKLMLSTSE---YSQS-PKMESLSSHRIDEDGENTQI 550 P+ + G S+ + L+ + + +SQS P + + + Sbjct: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979 Query: 551 EDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTD-----TRDDISIL 605 + +P +K +P + ++ PA + ++ K +T+ +D S+ Sbjct: 980 PKSTGQAPPAPAKSIPVKKET--KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037 Query: 606 ATGCKG------REETVAEDVC--IDLTCDSGSQAVPSPATRSEALSSVLD------QEE 651 A K + E C + GS+ P+ T +E + V + Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097 Query: 652 AMEIKEH-----HPEEGSSG--SEVEEIPETPCESQGEEL-----KEENMESVPLHLSLT 699 EI+E + SG ++ ++P P + + +VP + L Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLV 1157 Query: 700 ETQSQGLCLQKE---MPKKECSEAMEVETSVISIDSPQKLAILDQEL-----------EH 745 + Q Q + + E + K + + +ME +++ D Q+ + L+++ E Sbjct: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEE 1217 Query: 746 KEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAEN 805 K+ EE + +++ K+P+P D P E + Q + + +++ AE Sbjct: 1218 KKLIPEEEKIRSEEKKPLLEEKKPTPE-DKKLLP-EAKTSAPEEQKHDLLKSQVQ-IAEE 1274 Query: 806 RLDTKEEKSVEYEG--------DLKSGTAETEPVEQDSS------QPSLPLVRADDPLRL 851 +L+ + EG L SGT ++ P E D + QP P D + Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334 Query: 852 DQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHF 911 +E +T+++ S T S+ + Q SD + ++S S E P Sbjct: 1335 GKE----KTEKEDDKSDTSSSQQPKSPQGLSD---------TGYSSDGISSSLGEIP--- 1378 Query: 912 TLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYP--ESTIATSDVMSESMVETH 969 +IP T L G K + S+P S+ EST+ S++E Sbjct: 1379 ------SLIP--TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL-------SILEAQ 1423 Query: 970 DPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAE 1029 L K + P VSPE +E Q Sbjct: 1424 ASTLADEKSEKKTQPHE----------VSPEQPKDQEKTQ-------------------- 1453 Query: 1030 SVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIR 1089 S +T+ + E ++ E R + T + + PSS+ +EK + D T R Sbjct: 1454 ---SLSETLEITISEEEIKESQEERKD----TFKKDSQQDIPSSKDHKEKSEFVDDITTR 1506 Query: 1090 QSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALI 1149 + +P V++ + + + + G + + ++ +G ++ K +I Sbjct: 1507 R-----EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561 Query: 1150 ERPSQNNI-GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSG 1208 E + + G + E + +S++T++ K ++ GK T R Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKK---------EETKGKGKITAGKHRRLT 1612 Query: 1209 EKPVSAPGDDT---ESLHSQGEEEFD-MPQPPHGHVLHRHMRT--------IREVRTL-V 1255 K ++ +D S H + +E FD P+ + + +R +T+ + Sbjct: 1613 RKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIEL 1672 Query: 1256 TRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKAS 1315 I D Y + ++ + + + EEP +E + ++ S S G+ S S AS Sbjct: 1673 NSTIADKYSAESSQKKTSLYFD-EEPELEME----SLTDSPEDRSRGE----GSSSLHAS 1723 Query: 1316 SLHRTSSGTSLSAMHSSGSS 1335 S +S TS+S++ S Sbjct: 1724 SFTPGTSPTSVSSLDEDSDS 1743 Score = 46.2 bits (108), Expect = 3e-04 Identities = 149/724 (20%), Positives = 265/724 (36%), Gaps = 111/724 (15%) Query: 23 PCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQT-AGEERGDG 81 P + E QP++++ SG+ S+ +T KE P + P+Q G+E Sbjct: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKE---- 1337 Query: 82 NSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKG 141 K K D D+S+ S + + + SS LG P E++ Sbjct: 1338 --------KTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389 Query: 142 EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEV------ 195 + L +K+ +E + + + E T S L L+ + E+ T P+EV Sbjct: 1390 KGL-KKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPK 1447 Query: 196 DKEQLQSVTTNSGYT----RLSDVDANTAIKHEEQSNEDIPIAEQSSK------DIPVTA 245 D+E+ QS++ T + + ++ S +DIP ++ + DI Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRR 1507 Query: 246 QP--SKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ---IQKSP 300 +P S + E +P P R +S + Q S +E E ++ I+ S Sbjct: 1508 EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE--EDFIRKQIIEMSA 1565 Query: 301 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 360 + + +++D F ++ S + +EE + T +L+ + S D Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEE---TKGKGKITAGKHRRLTRKSSTSIDED 1622 Query: 361 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 420 + +AF +P E + R+ K ++ L GG L+ + + Sbjct: 1623 AGRRHSWHDEDDEAFDESP--------ELKYRETKSQESEELVVTGG----GGLRRFKTI 1670 Query: 421 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 480 EL ST++ + S SQ SL +P+ + SP E + G+ Sbjct: 1671 EL-------NSTIADKYSAESSQKKT-----SLYFDEEPELEMESLTDSP---EDRSRGE 1715 Query: 481 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 540 +H+SS T P SP + SL DS S S K + + HR Sbjct: 1716 GSSSLHASSFT----------PGTSPTSVS-SLDEDSDS---SPSHKKGESKQQRKARHR 1761 Query: 541 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 600 T IED+ + E + +L + E++ Q +K D +D Sbjct: 1762 PHGPLLPT-IEDSSEEEEL-------REEEELLKEQEKQREIEQQQRKSSSKKSKKD-KD 1812 Query: 601 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 660 ++ + R E + PS + E S + +A E++E H Sbjct: 1813 ELR-----AQRRRER--------------PKTPPSNLSPIEDASPTEELRQAAEMEELHR 1853 Query: 661 EEGSSGS-EVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE 719 S S +E PE S + ++ + + +P +SL + +QKE +K Sbjct: 1854 SSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKS 1913 Query: 720 AMEV 723 A E+ Sbjct: 1914 AEEM 1917 Score = 37.7 bits (86), Expect = 0.11 Identities = 152/794 (19%), Positives = 254/794 (31%), Gaps = 127/794 (15%) Query: 163 LGAEDTASSQLGF--GVLELSQSQDVEENTVPYEV--DKEQLQSVTTNSGYTRLSDVDAN 218 L E +S GF V LS V P+++ D E Q TT Sbjct: 144 LKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK----------Q 193 Query: 219 TAIKHEEQSNEDI---PIAEQSSKDIPVTAQPSKDV---------------HVVKEQNPP 260 ++ E+ E I P+ +Q K IP P +D +K Q P Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253 Query: 261 PARSEDMPF-SPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK-- 317 + P +P+ A + + S + ++ + +S +P + S + Q Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313 Query: 318 --------TVSSDGCSTPSREEGGCS--LASTPATTLHLLQLSGQRSLVQDSLS------ 361 S G + P + G + LA P T +Q G L Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373 Query: 362 ----TNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDT----SVLSEEGG--EPFQ 411 + P P A P V +P +Q G P L+++ G P + Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPG-VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432 Query: 412 KKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 471 + PV+ P +P P T Q+ P PP LP P++P P P+ Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKPPPQQ----PGPA 487 Query: 472 LEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---KNSPEDLGLSLTGDSCKLMLSTSEYS 528 G T K +P K SP+ G ST S Sbjct: 488 KPPPQQPGSAKPPSQQPGST----KPPPQQPGPAKPSPQQPG------------STKPPS 531 Query: 529 QSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFV--PAENDSILMNPAQ-------- 578 Q P S+ + + Q + T+P+S + K + P + S P+Q Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590 Query: 579 ---DGEVQLSQNDDKTKGDDTDTRDDI-SILATGCKGREETVAEDVCIDLTCDS--GSQA 632 E+ L + T+ + + S+ V E +C++ G Sbjct: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650 Query: 633 VPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESV 692 P P++ L + + + P+ + + + P+ E K + Sbjct: 651 APVPSSPQPKLKTA-PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709 Query: 693 P-LHLSLTETQSQ---GLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELE---- 744 P LH S + Q L K P KE S E + + ++ D P++ ++ + Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769 Query: 745 -----------HKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEG---VEKCSDSQ 790 K Q EE T+ + P P + SDS+ Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829 Query: 791 SWEDIAPEIEPCAENRLDTKEEKSVEYEGDLK-SGTAETEPVEQDSSQPSLPLVRADDPL 849 P E + ++D ++K + K S + +P+ + S P P A + Sbjct: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTV 889 Query: 850 RLDQELQQPQTQEK 863 Q+ +PQ Q + Sbjct: 890 PTPQQSPKPQEQSR 903 Score = 33.1 bits (74), Expect = 2.8 Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 4/120 (3%) Query: 1012 LEKPATGERKNGSTAVAESVASPQKTM--SVLSCICEARQENEARSEDPPTTPIRGNLLH 1069 + P+ R + + + +++P+KT L C EA + ++ T+P + Sbjct: 3534 IRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRP 3593 Query: 1070 FPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDV 1129 P G L D T++ + P K + P+SP S ++ P + + D+ Sbjct: 3594 TPLEIG--YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDI 3651 >gi|209862789 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 1 [Homo sapiens] Length = 2002 Score = 60.5 bits (145), Expect = 2e-08 Identities = 100/409 (24%), Positives = 160/409 (39%), Gaps = 82/409 (20%) Query: 108 SISQVIEQLPQPNRTSSVLGMSVE------SAPAVEEEKGEELEQKEKEKEEDTSGNT-- 159 ++ +V E+ + SSVL E S+ + EE+GEE E++ + D G Sbjct: 905 ALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGGVPWK 964 Query: 160 ----THSL---GAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRL 212 H+L +E+ + FG + ++ EE E D ++ + ++ +G RL Sbjct: 965 EAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRL 1024 Query: 213 SDV-----------DAN-TAIKHEEQSNEDIPIAEQSSKDIP---------VTAQPSKDV 251 V D + T I+ E+ P +E S+ P V ++P++ Sbjct: 1025 QQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIE 1084 Query: 252 HVVKEQNPP----PARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLST 307 E P +D +S S A E + A+ E+ L+++ S + E L Sbjct: 1085 GEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEG--EAELELRVSEDEEKLP- 1141 Query: 308 QEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDL 367 ++P +E G S A++P + Q S + S ST L Sbjct: 1142 -----------------ASPKHQERGPSQATSP---IRSPQESALLFIPVHSPSTEGPQL 1181 Query: 368 VAPSPDAFRSTP-----FIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVEL 422 P P A + F P P E+ + D P D + P + +PV L Sbjct: 1182 -PPVPAATQEKSPEERLFPEPLLPKEKP-KADAPSDLKAVHS----PIRS-----QPVTL 1230 Query: 423 ENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 471 P S SPQ P++ STP PP LPI SQPQ S + +PSP+ Sbjct: 1231 PEART-PVSPGSPQPQPPVAASTP--PPSPLPICSQPQPSTEATVPSPT 1276 Score = 35.0 bits (79), Expect = 0.73 Identities = 84/388 (21%), Positives = 134/388 (34%), Gaps = 79/388 (20%) Query: 576 PAQDGEVQ--------LSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCIDLTC 626 P QDG ++ + ++T G + ++ SI A +G E + E+ + L Sbjct: 844 PLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSI-AKRLRGTPERIELENYRLSLRQ 902 Query: 627 DSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKE 686 Q VP LSSVLD ++ SS SE+EE +GEE +E Sbjct: 903 AEALQEVPEETQAEHNLSSVLDTGAEEDVAS-----SSSESEMEE--------EGEEEEE 949 Query: 687 EN------------MESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQ 734 E E+V +H L + L K E E Sbjct: 950 EPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEE------------ 997 Query: 735 KLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWED 794 ++E E +E+E ++E E S + +V + +PLE W Sbjct: 998 -----EEEYEEEEEEDYDEEEEESSEA----GNQRLQQVMHAADPLE----IQADVHWTH 1044 Query: 795 IAPEIE-----PCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADD-- 847 I E P +E+ + E D+ S AE E + P DD Sbjct: 1045 IREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQ 1104 Query: 848 -----PLRLDQELQQP---QTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQS 899 P D+EL+ P + + + ++ED + A + + P +S Sbjct: 1105 HWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQES 1164 Query: 900 FCESSSETPFHFTLPKEGDIIPPLTGAT 927 + P H + EG +PP+ AT Sbjct: 1165 ---ALLFIPVH-SPSTEGPQLPPVPAAT 1188 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 60.1 bits (144), Expect = 2e-08 Identities = 208/1008 (20%), Positives = 325/1008 (32%), Gaps = 169/1008 (16%) Query: 189 NTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPS 248 N P +VD E L+ + +S+ + A EE NE+ P ++ +I V S Sbjct: 763 NLRPVDVDPECLRWTPVIVSNSVVSEEEEEEA---EEGENEE-PQCQERELEISVGKSVS 818 Query: 249 KDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEP------ 302 H KEQ+ SE P V A + +LS Q L L P Sbjct: 819 ---HENKEQDSYSVESEKKP-----EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGR 870 Query: 303 EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRS-LVQDSLS 361 + TQE D+ +K + + S P + G C G++S Q+ + Sbjct: 871 KNRKTQERFGDKDSKLLLEETSSAPQEQYGEC----------------GEKSEATQEQYT 914 Query: 362 TNSSDLVA----PSPDAFRSTPFIVPSSPTEQEGRQDK--PMDTSVLSEEGGEPFQKKLQ 415 + LVA PS D P S E Q K P EG E ++ Sbjct: 915 ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974 Query: 416 SG---------EPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIF 466 G E E E P P S+ P + P + F + + + + Sbjct: 975 EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034 Query: 467 IPSPS-----LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLM 521 + S L+E D + M T E + E E +N L Sbjct: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE-------LFPREYFRR 1087 Query: 522 LSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-----NSKFVPAENDSIL--- 573 LS+ + + S +ED E+ +DT + PV + K P E D+ Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147 Query: 574 -----------------MNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 616 P + +LS+ +SI G K + + Sbjct: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES 1207 Query: 617 AEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI-PET 675 E V + +P P R E + EEA E EE ++ SEV P Sbjct: 1208 EETV-------EPKEDMPLPEERKEEEEMQAEAEEA----EEGEEEDAASSEVPAASPAD 1256 Query: 676 PCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQK 735 S E KE +E ++E Q Q Q+E+ + E E + D Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDA 1316 Query: 736 LAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS---CEPLEGVEKCSDSQSW 792 D LE +++ EE + + DVKE P V S + EK D + Sbjct: 1317 DDEDDGHLESTKKKELEEQPTRE------DVKE-EPGVQESFLDANMQKSREKIKDKEET 1369 Query: 793 EDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAET-----EPVEQDSSQPSLPLVRADD 847 E + E +P + + +++ E + + S T E E E S+ L V+A Sbjct: 1370 ELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQ 1429 Query: 848 PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSET 907 L ++ + + +L + + Q D + + A S S Sbjct: 1430 SLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSH 1489 Query: 908 PFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVE 967 P +P L G+ ++ P++ S +S + TS +M V Sbjct: 1490 PSQSVRSVSSPNVPALES------GYTQISPEQGS----LSAPSMQNMETSPMMDVPSVS 1539 Query: 968 THDP-ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTA 1026 H ++ SG D G S ES N E P++ + G + Sbjct: 1540 DHSQQVVDSGFSDLG----------------------SIESTTENYENPSSYDSTMGGSI 1577 Query: 1027 VAESVA---------SPQKTMSVLSCICEARQENEARS----EDPPTTPIRGNLLHFPSS 1073 S + S +++ SC+ + + S + P + P S Sbjct: 1578 CGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQS 1637 Query: 1074 QGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQ 1121 E Q QQP P P + P P Q P PQ Sbjct: 1638 CVVERPPS-------NQQQQPPPP--PPQQPQPPPPQPQPAPQPPPPQ 1676 Score = 58.2 bits (139), Expect = 8e-08 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 40/336 (11%) Query: 59 KENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKV--ADPVDSSNLDTCGSISQVIEQL 116 KE+ L E+ E + G E ++V A P DSSN + +E+ Sbjct: 1214 KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273 Query: 117 PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFG 176 + R S S EE+ +ELE+ E E+EED + T + +D + G Sbjct: 1274 EEKPRVSEEQRQS--------EEEQQELEEPEPEEEEDAAAETAQN---DDHDADDEDDG 1322 Query: 177 VLELSQSQDVEENTVPYEVD-----KEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 231 LE ++ +++EE +V +E ++ D + EEQ + D Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382 Query: 232 PIAEQ----SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPF-----------SPKASVA 276 + + S D + +++ +KE+ P D+ S + A Sbjct: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGA 1442 Query: 277 AMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSL 336 + +E L+A + ++S Q + P+ +S ED + + S S PS+ S Sbjct: 1443 YQDCEETLAACQTLQSYTQADEDPQ---MSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499 Query: 337 ASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSP 372 + PA Q+S + Q SLS S + SP Sbjct: 1500 PNVPALESGYTQISPE----QGSLSAPSMQNMETSP 1531 Score = 56.2 bits (134), Expect = 3e-07 Identities = 109/518 (21%), Positives = 190/518 (36%), Gaps = 73/518 (14%) Query: 3 GEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENP 62 GE+ D S++ + + E +PE V E++ S R Q E P Sbjct: 1239 GEEEDAASSEVPAASPADSSNSPETETKEPE--VEEEEEKPRVSEEQRQSEEEQQELEEP 1296 Query: 63 VLDVVSNPE-QTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNR 121 + + +TA + D + + HL+ K L+ + V E+ P Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTK------KKELEEQPTREDVKEE---PGV 1347 Query: 122 TSSVLGMSVE-SAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTAS---------- 170 S L +++ S +++++ EL+ +E++ DTS + G+ED Sbjct: 1348 QESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI 1407 Query: 171 ----------SQLGFGVLELSQSQDVEENTV---PYEVDKEQLQSVTTNSGYTRLSDVDA 217 S+L ++ QS EE++ Y+ +E L + T YT+ +D D Sbjct: 1408 ELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQ-ADEDP 1466 Query: 218 NTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK----- 272 ++ ED +E +S V + PS+ V V N P S SP+ Sbjct: 1467 QMSMV------EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLS 1520 Query: 273 -ASVAAMEAKEQLSAQELMESGLQIQKSPEPE---VLSTQEDLFDQS--NKTVSSDGCST 326 S+ ME + + + Q+ S + + ST E+ + S + T+ C Sbjct: 1521 APSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN 1580 Query: 327 PSREEGGCS---LASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP--FI 381 S + CS L+S+ + T ++ Q + + S S V P+ + +P + Sbjct: 1581 -SSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCV 1639 Query: 382 VPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI 441 V P+ Q+ + P P Q + +P PP P Q P Sbjct: 1640 VERPPSNQQQQPPPP-----------PPQQPQPPPPQPQPAPQPP--PPQQQPQQQPQPQ 1686 Query: 442 SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDG 479 Q P PP P ++ F P+P + E G Sbjct: 1687 PQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESG 1724 Score = 36.6 bits (83), Expect = 0.25 Identities = 67/348 (19%), Positives = 134/348 (38%), Gaps = 57/348 (16%) Query: 999 PETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDP 1058 P+ + SEE+++ + P ERK AE+ + E +E+ A SE P Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE-----------EGEEEDAASSEVP 1250 Query: 1059 PTTPIRGNLLHFPSSQG-----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMV 1113 +P + + P ++ EEE+EK RQS++ + + ++P + Sbjct: 1251 AASPADSS--NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL---EEPEPEEEEDAA 1305 Query: 1114 IQGPSSPQGEAMVTDVLEDQKEG--RSTNKENPSKALIERPSQNNIGIQTMECSLRVPET 1171 + + +A +D+ +G ST K K L E+P++ ++ + + Sbjct: 1306 AETAQNDDHDA------DDEDDGHLESTKK----KELEEQPTREDVKEEPGVQESFLDAN 1355 Query: 1172 VSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFD 1231 + + + IK+ E + ++ + V + E E L EEE Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE-- 1413 Query: 1232 MPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET- 1290 + PH + + T++ V++L + + ++ EE + CQ ++ Sbjct: 1414 --EIPHSEL---DLETVQAVQSLTQ---------EESSEHEGAYQDCEETLAACQTLQSY 1459 Query: 1291 -------EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHS 1331 ++S + +S ISS S S R+ S ++ A+ S Sbjct: 1460 TQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALES 1507 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 60.1 bits (144), Expect = 2e-08 Identities = 208/1008 (20%), Positives = 325/1008 (32%), Gaps = 169/1008 (16%) Query: 189 NTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPS 248 N P +VD E L+ + +S+ + A EE NE+ P ++ +I V S Sbjct: 763 NLRPVDVDPECLRWTPVIVSNSVVSEEEEEEA---EEGENEE-PQCQERELEISVGKSVS 818 Query: 249 KDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEP------ 302 H KEQ+ SE P V A + +LS Q L L P Sbjct: 819 ---HENKEQDSYSVESEKKP-----EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGR 870 Query: 303 EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRS-LVQDSLS 361 + TQE D+ +K + + S P + G C G++S Q+ + Sbjct: 871 KNRKTQERFGDKDSKLLLEETSSAPQEQYGEC----------------GEKSEATQEQYT 914 Query: 362 TNSSDLVA----PSPDAFRSTPFIVPSSPTEQEGRQDK--PMDTSVLSEEGGEPFQKKLQ 415 + LVA PS D P S E Q K P EG E ++ Sbjct: 915 ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974 Query: 416 SG---------EPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIF 466 G E E E P P S+ P + P + F + + + + Sbjct: 975 EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034 Query: 467 IPSPS-----LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLM 521 + S L+E D + M T E + E E +N L Sbjct: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE-------LFPREYFRR 1087 Query: 522 LSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-----NSKFVPAENDSIL--- 573 LS+ + + S +ED E+ +DT + PV + K P E D+ Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147 Query: 574 -----------------MNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 616 P + +LS+ +SI G K + + Sbjct: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES 1207 Query: 617 AEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI-PET 675 E V + +P P R E + EEA E EE ++ SEV P Sbjct: 1208 EETV-------EPKEDMPLPEERKEEEEMQAEAEEA----EEGEEEDAASSEVPAASPAD 1256 Query: 676 PCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQK 735 S E KE +E ++E Q Q Q+E+ + E E + D Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDA 1316 Query: 736 LAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS---CEPLEGVEKCSDSQSW 792 D LE +++ EE + + DVKE P V S + EK D + Sbjct: 1317 DDEDDGHLESTKKKELEEQPTRE------DVKE-EPGVQESFLDANMQKSREKIKDKEET 1369 Query: 793 EDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAET-----EPVEQDSSQPSLPLVRADD 847 E + E +P + + +++ E + + S T E E E S+ L V+A Sbjct: 1370 ELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQ 1429 Query: 848 PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSET 907 L ++ + + +L + + Q D + + A S S Sbjct: 1430 SLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSH 1489 Query: 908 PFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVE 967 P +P L G+ ++ P++ S +S + TS +M V Sbjct: 1490 PSQSVRSVSSPNVPALES------GYTQISPEQGS----LSAPSMQNMETSPMMDVPSVS 1539 Query: 968 THDP-ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTA 1026 H ++ SG D G S ES N E P++ + G + Sbjct: 1540 DHSQQVVDSGFSDLG----------------------SIESTTENYENPSSYDSTMGGSI 1577 Query: 1027 VAESVA---------SPQKTMSVLSCICEARQENEARS----EDPPTTPIRGNLLHFPSS 1073 S + S +++ SC+ + + S + P + P S Sbjct: 1578 CGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQS 1637 Query: 1074 QGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQ 1121 E Q QQP P P + P P Q P PQ Sbjct: 1638 CVVERPPS-------NQQQQPPPP--PPQQPQPPPPQPQPAPQPPPPQ 1676 Score = 58.2 bits (139), Expect = 8e-08 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 40/336 (11%) Query: 59 KENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKV--ADPVDSSNLDTCGSISQVIEQL 116 KE+ L E+ E + G E ++V A P DSSN + +E+ Sbjct: 1214 KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273 Query: 117 PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFG 176 + R S S EE+ +ELE+ E E+EED + T + +D + G Sbjct: 1274 EEKPRVSEEQRQS--------EEEQQELEEPEPEEEEDAAAETAQN---DDHDADDEDDG 1322 Query: 177 VLELSQSQDVEENTVPYEVD-----KEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 231 LE ++ +++EE +V +E ++ D + EEQ + D Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382 Query: 232 PIAEQ----SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPF-----------SPKASVA 276 + + S D + +++ +KE+ P D+ S + A Sbjct: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGA 1442 Query: 277 AMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSL 336 + +E L+A + ++S Q + P+ +S ED + + S S PS+ S Sbjct: 1443 YQDCEETLAACQTLQSYTQADEDPQ---MSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499 Query: 337 ASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSP 372 + PA Q+S + Q SLS S + SP Sbjct: 1500 PNVPALESGYTQISPE----QGSLSAPSMQNMETSP 1531 Score = 56.2 bits (134), Expect = 3e-07 Identities = 109/518 (21%), Positives = 190/518 (36%), Gaps = 73/518 (14%) Query: 3 GEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENP 62 GE+ D S++ + + E +PE V E++ S R Q E P Sbjct: 1239 GEEEDAASSEVPAASPADSSNSPETETKEPE--VEEEEEKPRVSEEQRQSEEEQQELEEP 1296 Query: 63 VLDVVSNPE-QTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNR 121 + + +TA + D + + HL+ K L+ + V E+ P Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTK------KKELEEQPTREDVKEE---PGV 1347 Query: 122 TSSVLGMSVE-SAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTAS---------- 170 S L +++ S +++++ EL+ +E++ DTS + G+ED Sbjct: 1348 QESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI 1407 Query: 171 ----------SQLGFGVLELSQSQDVEENTV---PYEVDKEQLQSVTTNSGYTRLSDVDA 217 S+L ++ QS EE++ Y+ +E L + T YT+ +D D Sbjct: 1408 ELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQ-ADEDP 1466 Query: 218 NTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK----- 272 ++ ED +E +S V + PS+ V V N P S SP+ Sbjct: 1467 QMSMV------EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLS 1520 Query: 273 -ASVAAMEAKEQLSAQELMESGLQIQKSPEPE---VLSTQEDLFDQS--NKTVSSDGCST 326 S+ ME + + + Q+ S + + ST E+ + S + T+ C Sbjct: 1521 APSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN 1580 Query: 327 PSREEGGCS---LASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP--FI 381 S + CS L+S+ + T ++ Q + + S S V P+ + +P + Sbjct: 1581 -SSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCV 1639 Query: 382 VPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI 441 V P+ Q+ + P P Q + +P PP P Q P Sbjct: 1640 VERPPSNQQQQPPPP-----------PPQQPQPPPPQPQPAPQPP--PPQQQPQQQPQPQ 1686 Query: 442 SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDG 479 Q P PP P ++ F P+P + E G Sbjct: 1687 PQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESG 1724 Score = 36.6 bits (83), Expect = 0.25 Identities = 67/348 (19%), Positives = 134/348 (38%), Gaps = 57/348 (16%) Query: 999 PETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDP 1058 P+ + SEE+++ + P ERK AE+ + E +E+ A SE P Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE-----------EGEEEDAASSEVP 1250 Query: 1059 PTTPIRGNLLHFPSSQG-----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMV 1113 +P + + P ++ EEE+EK RQS++ + + ++P + Sbjct: 1251 AASPADSS--NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL---EEPEPEEEEDAA 1305 Query: 1114 IQGPSSPQGEAMVTDVLEDQKEG--RSTNKENPSKALIERPSQNNIGIQTMECSLRVPET 1171 + + +A +D+ +G ST K K L E+P++ ++ + + Sbjct: 1306 AETAQNDDHDA------DDEDDGHLESTKK----KELEEQPTREDVKEEPGVQESFLDAN 1355 Query: 1172 VSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFD 1231 + + + IK+ E + ++ + V + E E L EEE Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE-- 1413 Query: 1232 MPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET- 1290 + PH + + T++ V++L + + ++ EE + CQ ++ Sbjct: 1414 --EIPHSEL---DLETVQAVQSLTQ---------EESSEHEGAYQDCEETLAACQTLQSY 1459 Query: 1291 -------EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHS 1331 ++S + +S ISS S S R+ S ++ A+ S Sbjct: 1460 TQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALES 1507 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 60.1 bits (144), Expect = 2e-08 Identities = 208/1008 (20%), Positives = 325/1008 (32%), Gaps = 169/1008 (16%) Query: 189 NTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPS 248 N P +VD E L+ + +S+ + A EE NE+ P ++ +I V S Sbjct: 763 NLRPVDVDPECLRWTPVIVSNSVVSEEEEEEA---EEGENEE-PQCQERELEISVGKSVS 818 Query: 249 KDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEP------ 302 H KEQ+ SE P V A + +LS Q L L P Sbjct: 819 ---HENKEQDSYSVESEKKP-----EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGR 870 Query: 303 EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRS-LVQDSLS 361 + TQE D+ +K + + S P + G C G++S Q+ + Sbjct: 871 KNRKTQERFGDKDSKLLLEETSSAPQEQYGEC----------------GEKSEATQEQYT 914 Query: 362 TNSSDLVA----PSPDAFRSTPFIVPSSPTEQEGRQDK--PMDTSVLSEEGGEPFQKKLQ 415 + LVA PS D P S E Q K P EG E ++ Sbjct: 915 ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974 Query: 416 SG---------EPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIF 466 G E E E P P S+ P + P + F + + + + Sbjct: 975 EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034 Query: 467 IPSPS-----LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLM 521 + S L+E D + M T E + E E +N L Sbjct: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE-------LFPREYFRR 1087 Query: 522 LSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-----NSKFVPAENDSIL--- 573 LS+ + + S +ED E+ +DT + PV + K P E D+ Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147 Query: 574 -----------------MNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 616 P + +LS+ +SI G K + + Sbjct: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES 1207 Query: 617 AEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI-PET 675 E V + +P P R E + EEA E EE ++ SEV P Sbjct: 1208 EETV-------EPKEDMPLPEERKEEEEMQAEAEEA----EEGEEEDAASSEVPAASPAD 1256 Query: 676 PCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQK 735 S E KE +E ++E Q Q Q+E+ + E E + D Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDA 1316 Query: 736 LAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS---CEPLEGVEKCSDSQSW 792 D LE +++ EE + + DVKE P V S + EK D + Sbjct: 1317 DDEDDGHLESTKKKELEEQPTRE------DVKE-EPGVQESFLDANMQKSREKIKDKEET 1369 Query: 793 EDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAET-----EPVEQDSSQPSLPLVRADD 847 E + E +P + + +++ E + + S T E E E S+ L V+A Sbjct: 1370 ELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQ 1429 Query: 848 PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSET 907 L ++ + + +L + + Q D + + A S S Sbjct: 1430 SLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSH 1489 Query: 908 PFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVE 967 P +P L G+ ++ P++ S +S + TS +M V Sbjct: 1490 PSQSVRSVSSPNVPALES------GYTQISPEQGS----LSAPSMQNMETSPMMDVPSVS 1539 Query: 968 THDP-ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTA 1026 H ++ SG D G S ES N E P++ + G + Sbjct: 1540 DHSQQVVDSGFSDLG----------------------SIESTTENYENPSSYDSTMGGSI 1577 Query: 1027 VAESVA---------SPQKTMSVLSCICEARQENEARS----EDPPTTPIRGNLLHFPSS 1073 S + S +++ SC+ + + S + P + P S Sbjct: 1578 CGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQS 1637 Query: 1074 QGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQ 1121 E Q QQP P P + P P Q P PQ Sbjct: 1638 CVVERPPS-------NQQQQPPPP--PPQQPQPPPPQPQPAPQPPPPQ 1676 Score = 58.2 bits (139), Expect = 8e-08 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 40/336 (11%) Query: 59 KENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKV--ADPVDSSNLDTCGSISQVIEQL 116 KE+ L E+ E + G E ++V A P DSSN + +E+ Sbjct: 1214 KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273 Query: 117 PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFG 176 + R S S EE+ +ELE+ E E+EED + T + +D + G Sbjct: 1274 EEKPRVSEEQRQS--------EEEQQELEEPEPEEEEDAAAETAQN---DDHDADDEDDG 1322 Query: 177 VLELSQSQDVEENTVPYEVD-----KEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 231 LE ++ +++EE +V +E ++ D + EEQ + D Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382 Query: 232 PIAEQ----SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPF-----------SPKASVA 276 + + S D + +++ +KE+ P D+ S + A Sbjct: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGA 1442 Query: 277 AMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSL 336 + +E L+A + ++S Q + P+ +S ED + + S S PS+ S Sbjct: 1443 YQDCEETLAACQTLQSYTQADEDPQ---MSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499 Query: 337 ASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSP 372 + PA Q+S + Q SLS S + SP Sbjct: 1500 PNVPALESGYTQISPE----QGSLSAPSMQNMETSP 1531 Score = 56.2 bits (134), Expect = 3e-07 Identities = 109/518 (21%), Positives = 190/518 (36%), Gaps = 73/518 (14%) Query: 3 GEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENP 62 GE+ D S++ + + E +PE V E++ S R Q E P Sbjct: 1239 GEEEDAASSEVPAASPADSSNSPETETKEPE--VEEEEEKPRVSEEQRQSEEEQQELEEP 1296 Query: 63 VLDVVSNPE-QTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNR 121 + + +TA + D + + HL+ K L+ + V E+ P Sbjct: 1297 EPEEEEDAAAETAQNDDHDADDEDDGHLESTK------KKELEEQPTREDVKEE---PGV 1347 Query: 122 TSSVLGMSVE-SAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTAS---------- 170 S L +++ S +++++ EL+ +E++ DTS + G+ED Sbjct: 1348 QESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI 1407 Query: 171 ----------SQLGFGVLELSQSQDVEENTV---PYEVDKEQLQSVTTNSGYTRLSDVDA 217 S+L ++ QS EE++ Y+ +E L + T YT+ +D D Sbjct: 1408 ELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQ-ADEDP 1466 Query: 218 NTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK----- 272 ++ ED +E +S V + PS+ V V N P S SP+ Sbjct: 1467 QMSMV------EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLS 1520 Query: 273 -ASVAAMEAKEQLSAQELMESGLQIQKSPEPE---VLSTQEDLFDQS--NKTVSSDGCST 326 S+ ME + + + Q+ S + + ST E+ + S + T+ C Sbjct: 1521 APSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN 1580 Query: 327 PSREEGGCS---LASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP--FI 381 S + CS L+S+ + T ++ Q + + S S V P+ + +P + Sbjct: 1581 -SSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCV 1639 Query: 382 VPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI 441 V P+ Q+ + P P Q + +P PP P Q P Sbjct: 1640 VERPPSNQQQQPPPP-----------PPQQPQPPPPQPQPAPQPP--PPQQQPQQQPQPQ 1686 Query: 442 SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDG 479 Q P PP P ++ F P+P + E G Sbjct: 1687 PQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESG 1724 Score = 36.6 bits (83), Expect = 0.25 Identities = 67/348 (19%), Positives = 134/348 (38%), Gaps = 57/348 (16%) Query: 999 PETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDP 1058 P+ + SEE+++ + P ERK AE+ + E +E+ A SE P Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE-----------EGEEEDAASSEVP 1250 Query: 1059 PTTPIRGNLLHFPSSQG-----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMV 1113 +P + + P ++ EEE+EK RQS++ + + ++P + Sbjct: 1251 AASPADSS--NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL---EEPEPEEEEDAA 1305 Query: 1114 IQGPSSPQGEAMVTDVLEDQKEG--RSTNKENPSKALIERPSQNNIGIQTMECSLRVPET 1171 + + +A +D+ +G ST K K L E+P++ ++ + + Sbjct: 1306 AETAQNDDHDA------DDEDDGHLESTKK----KELEEQPTREDVKEEPGVQESFLDAN 1355 Query: 1172 VSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFD 1231 + + + IK+ E + ++ + V + E E L EEE Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE-- 1413 Query: 1232 MPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET- 1290 + PH + + T++ V++L + + ++ EE + CQ ++ Sbjct: 1414 --EIPHSEL---DLETVQAVQSLTQ---------EESSEHEGAYQDCEETLAACQTLQSY 1459 Query: 1291 -------EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHS 1331 ++S + +S ISS S S R+ S ++ A+ S Sbjct: 1460 TQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALES 1507 >gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] Length = 3957 Score = 58.5 bits (140), Expect = 6e-08 Identities = 223/1145 (19%), Positives = 417/1145 (36%), Gaps = 161/1145 (14%) Query: 136 VEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD----VEENTV 191 VE+EKG L Q+E +K E+ + L TA S+ G V + ++ +E + Sbjct: 2029 VEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDAAGGKEKVL 2088 Query: 192 PYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDV 251 +++ E +QSV + R S+V +EQ + D+ I+ P + Sbjct: 2089 SHKI-PEPVQSVPEEESH-RESEVPKEKMA--DEQGDMDLQIS-------PDRKTSTDFS 2137 Query: 252 HVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDL 311 V+K++ + + S + A + + L++ L K LS Q Sbjct: 2138 EVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGA 2197 Query: 312 FDQSNKTVSSDGCS----------TP--SREEG--GCSLASTPATTLHLLQLSGQRSLVQ 357 D S++++ ++G + TP S EE LA TP T+ L S ++S Q Sbjct: 2198 LDGSSESLKNEGVAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSEEQ 2257 Query: 358 DSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQE---GRQDKPMDTSVLSEEGGEPFQKKL 414 + S+ + RS PT ++ G +++ + SE E FQK+ Sbjct: 2258 TGETKESTK--TETTTEIRSE----KEHPTTKDITGGSEERGATVTEDSETSTESFQKEA 2311 Query: 415 QSGEPVELENPPLLPESTVSPQASTPISQSTPV-FPPGSLPIPSQPQFSHDIFIPSPSLE 473 G P + +P + T S S +++ TP + Q F E Sbjct: 2312 TLGSPKD-TSPKRQDDCTGS--CSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSE 2368 Query: 474 EQSNDGKKDGD--MHSSSLTVECSKTSEIEPK---NSPEDLGLSLTGDSCKLMLSTSEYS 528 Q + D + +V+ +E +P+ SP+ L L+L +++ + ++ S Sbjct: 2369 VQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDSEVLSAVADDS 2428 Query: 529 ----------QSPKMESLSSHRIDEDGENTQIE--------DTEPMSPVLNSKFVP---- 566 SP +E SSH+ + E + ++ ++ P+ P + + P Sbjct: 2429 LAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFP 2488 Query: 567 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCK---GREETVAEDV 620 A + L+ +L ++ D + D D+ + S++ + K + +E+V Sbjct: 2489 LPAAVAKTELLTEVASVRSRLLRDPDGSAED--DSLEQTSLMESSGKSPLSPDTPSSEEV 2546 Query: 621 CIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQ 680 ++T + + P PA E D E E K PEE + E + Sbjct: 2547 SYEVTPKTTDVSTPKPAVIHECAEE--DDSENGEKKRFTPEEEMFKMVTKIKMFDELEQE 2604 Query: 681 GEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILD 740 ++ ++ E S + + + PK S E V+ +K++ Sbjct: 2605 AKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVS--- 2661 Query: 741 QELEHKEQEAWEEATSEDSSVV---IVDVKEPSP----------RVDVSCEPLEGVE--- 784 E E + DS ++ ++ V+ PSP +V +P+ + Sbjct: 2662 -SSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTF 2720 Query: 785 KCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL---- 840 K ++ E E E +E+ L ++ +V E + +S + + +D+ QP + Sbjct: 2721 KMNEDTQEEPGKSEEEKDSESHL-AEDRHAVSTEAEDRS----YDKLNRDTDQPKICDGH 2775 Query: 841 ---PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHAS 897 + + + LQ P + + +A D E ++L A + Sbjct: 2776 GCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEELDVSRAESP 2835 Query: 898 QSFCES---SSETPFHFTLPKEGDIIPPLTGATPPL--IGHLKLEPKRHSTPIGISNYPE 952 Q+ C S SS + L EG + AT + K + + P + Sbjct: 2836 QADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETFENLPKDCPSQDS 2895 Query: 953 STIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNL 1012 S +D S + P+ + D P ++ SP +S F+ Sbjct: 2896 SITTQTDRFSMDV-----PVSDLAENDEIYDP----------QITSPYENVPSQSF-FSS 2939 Query: 1013 EKPATGERKNGSTAVAES-VASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFP 1071 E+ T N +T+ S V S T V + + S++ + G + Sbjct: 2940 EESKTQTDANHTTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKE---SNFEGQDIKME 2996 Query: 1072 SSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLE 1131 S Q E +++ D ++ S +P +S V K++I + +++ E Sbjct: 2997 SQQ-ESTLWEMQSD-SVSSSFEP--TMSATTTVVGEQISKVII--TKTDVDSDSWSEIRE 3050 Query: 1132 DQKEGRSTNKENPSK---ALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTS 1188 D + + KE K +++R SQ P+T A T T E+GT Sbjct: 3051 DDEAFEARVKEEEQKIFGLMVDRQSQGT-----------TPDTTPARTPT-----EEGTP 3094 Query: 1189 TVDQN 1193 T +QN Sbjct: 3095 TSEQN 3099 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 57.0 bits (136), Expect = 2e-07 Identities = 98/468 (20%), Positives = 170/468 (36%), Gaps = 52/468 (11%) Query: 483 GDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRID 542 G H +L E + + +P S G+ +E P+ E + + + Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP---------EAEGEAQPESEGVEAPEAE 1857 Query: 543 EDGENT----QIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQL-SQNDDKTKGDDTD 597 D + Q E + +P + P D + P + EVQ S+ + + + Sbjct: 1858 GDAQEAEGEAQPESEDVEAPEAEGEAQPESED--VETPEAEWEVQPESEGAEAPEAEKEA 1915 Query: 598 TRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEA----- 652 + S+ A +G +E +E ++ +A SE + S +EEA Sbjct: 1916 QPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESE 1975 Query: 653 ----MEIK-EHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLC 707 +E++ E EG + E E++ E + +E +EE + +S G+ Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEE-----------AQPESDGV- 2023 Query: 708 LQKEMPKKECSEAMEVETSVISID---SPQKLAILDQELEHKEQEAWEEATSEDSSV--- 761 + PK E EA EVE + P+ + E E + QEA E + Sbjct: 2024 --EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPE 2081 Query: 762 -VIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDI-APEIEPCAENRLDTKEEKSVEYEG 819 VD +E E +E E ++Q E I APE E A+ + E E E Sbjct: 2082 SEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEA 2141 Query: 820 DLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQ 879 +S E + E ++ S + + EL+ + E + E S+ A + Sbjct: 2142 QPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPE-SEGIEAPE 2200 Query: 880 LSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGAT 927 +A+ + G + A + E+ E T EG+ P G T Sbjct: 2201 AEGEAQPELEGVEAPEAEE---EAQPEPEGVETPEAEGEAQPESEGET 2245 Score = 43.9 bits (102), Expect = 0.002 Identities = 97/445 (21%), Positives = 153/445 (34%), Gaps = 64/445 (14%) Query: 30 SQPESQVLEDDSGSHFSML-SRHLPNLQTHKENPVLDVVSNPE-------------QTAG 75 +QPES+V+E + S + L+ E + + PE Q A Sbjct: 1954 TQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAE 2013 Query: 76 EERGDGNSGFNEHLK-ENKVADPVDSSNLDTCGSISQVIE--QLPQPNRTSSVLGMSVES 132 EE + G K E + A V+ T G + + P+ + V+ Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073 Query: 133 APAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVP 192 A + E+++ +E E E + AE A G E E + Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGI- 2132 Query: 193 YEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH 252 E + + ++ + G V+A A + +E I E + AQP Sbjct: 2133 -EAPEAEGEAQPESEG------VEAQDAEGEAQPESEGIEAQEAEEE-----AQPE---- 2176 Query: 253 VVKEQNPPPARSEDMPFSP--KASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQED 310 ++ P A E P S +A A EA+ +L E E+ + Q PEPE + T E Sbjct: 2177 -LEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQ--PEPEGVETPEA 2233 Query: 311 LFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAP 370 + S+G T ++G +P +L GQ +S S D P Sbjct: 2234 ---EGEAQPESEG-ETQGEKKG------SPQVSLG----DGQSEEASESSSPVPEDRPTP 2279 Query: 371 SPDAFRSTPFIVPSSPTEQEGRQ--------DKPMDTSVLSEEGGEPFQKKLQSGEP-VE 421 P TP P S T + K + + + P K +G P E Sbjct: 2280 PPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKS--TGTPHAE 2337 Query: 422 LENPPLLPESTVSPQASTPISQSTP 446 + + PES+ S Q P+ TP Sbjct: 2338 RKATRMYPESSTSEQEEAPLGSRTP 2362 Score = 40.8 bits (94), Expect = 0.013 Identities = 156/754 (20%), Positives = 272/754 (36%), Gaps = 124/754 (16%) Query: 587 NDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSV 646 N+D+ + D + R ++ E TV E+V ++ T + T E L Sbjct: 1272 NEDEAERDSEEQRASSNLEQLA----ENTVQEEVQLEETKEG---------TEGEGL--- 1315 Query: 647 LDQEEAMEIKEHHPEEG--SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQ 704 QEEA++++E EEG G ++EE ET E +G++ +E +E + ET + Sbjct: 1316 --QEEAVQLEETKTEEGLQEEGVQLEETKET--EGEGQQEEEAQLEEI------EETGGE 1365 Query: 705 GLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIV 764 GL ++ + +E E E +++ K L +E QE EA+S D Sbjct: 1366 GL-QEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQEL-SEASSPDGKGSQE 1423 Query: 765 D---VKEPSPRVDVSCE--PLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEG 819 D +E + R S E P EG E+ ++ S E +P A R + S G Sbjct: 1424 DDPVQEEEAGRASASAEPCPAEGTEEPTEPPSH---LSETDPSASER----QSGSQLEPG 1476 Query: 820 DLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQ 879 K A E +QP+ + L TE + +A+ Sbjct: 1477 LEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLAS 1536 Query: 880 LSSDAEAQ-------KLGKPSAHASQSFC---ESSSETPFHFTLPKEGDII--PPLTGAT 927 ++ A+ L + +A Q + S++ + G ++ PP T Sbjct: 1537 AVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRAGRMVLEPPREALT 1596 Query: 928 PPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDS-GAAPDV 986 L+ L+ + +RH G+ N + T + S +P L + G G + Sbjct: 1597 GELL--LQTQQRRHRLR-GLRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEG 1653 Query: 987 DD----KLCLRMKL--VSPETE--ASEESLQFNLEKPATGERKNGSTAVAESV-ASPQKT 1037 ++ + C+R K+ +SP+ A+ ++ + +RK G E+ +P KT Sbjct: 1654 EEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKT 1713 Query: 1038 MSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKP 1097 + R+ + L P G +E E EG + + + P Sbjct: 1714 HT---------DPTSTRTVQGAEGGLGPGLSQGP---GVDEGEDGEGSQRLNRDKDP--- 1758 Query: 1098 ISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNI 1157 GEA D + ++EG++ N E + + + Q Sbjct: 1759 ----------------------KLGEA-EGDAMAQEREGKTHNSETSAGSELGEAEQEGE 1795 Query: 1158 GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT--VQTERGSGE-----K 1210 GI ET + N+ + + DQ+ G+ D ++ GE + Sbjct: 1796 GISER------GETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESE 1849 Query: 1211 PVSAPGDDTESLHSQGE---EEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDG 1267 V AP + ++ ++GE E D+ P + E V + + Sbjct: 1850 GVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDV-ETPEAEWEVQPESEGAEA 1908 Query: 1268 TEVERKVTEETEEPIVECQECETEVSPSQTGGSS 1301 E E++ ETE VE E E E P G + Sbjct: 1909 PEAEKEAQPETES--VEALETEGEDEPESEGAEA 1940 Score = 38.9 bits (89), Expect = 0.050 Identities = 79/329 (24%), Positives = 107/329 (32%), Gaps = 87/329 (26%) Query: 1236 PHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPS 1295 P GH H H R D + + ++ VT++ P + C+ P Sbjct: 661 PRGHPRHSHYRK-------------DTH----SPLDSSVTKQVPRPPERRRACQDGSVPR 703 Query: 1296 QTGGSS-------GDLGDISSFSSKASSLHRTSSGTSLSAMHS----------------- 1331 +G SS G+L SS S + L TSS T A+HS Sbjct: 704 YSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWA 763 Query: 1332 --SGSSGKGAGPLRGKTS-----------GTEPADFALPSS-------RGGPGKLSPRKG 1371 +GS P+ TS G E D PSS R G + P + Sbjct: 764 GDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRS 823 Query: 1372 --VSQTGTPVCEE---DGDAGLGIRQGGKAPVTPRGR---GRRGRPPSRTTGTRETAVPG 1423 SQ GT +E G P PRGR RR T + ++ G Sbjct: 824 HCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARG 883 Query: 1424 P-----LGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGP 1478 P G P SP S ++RR+ GA R S E ++ GP Sbjct: 884 PGGSPQEGTRQPGPTPSPGPNS---------GASRRSSASQGAGSRGLSEEKTLRSGGGP 934 Query: 1479 SDGLDASSPGNSFVGL----RVVAKWSSN 1503 +AS S + VV +W N Sbjct: 935 QGQEEASGVSPSSLPRSSPEAVVREWLDN 963 Score = 34.3 bits (77), Expect = 1.2 Identities = 52/233 (22%), Positives = 88/233 (37%), Gaps = 39/233 (16%) Query: 71 EQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSV 130 E+ + E+R N E L EN V + V + E+ Q T + G+ Sbjct: 1277 ERDSEEQRASSNL---EQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQE 1333 Query: 131 ESAPAVE----EEKGEELEQKEKEKEEDTSGNTTHSLGA--EDTASSQLGFGVLELSQSQ 184 E E E +G++ E+ + E+ E+T G G E+ G G+ + + Sbjct: 1334 EGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEG-GLQGEALEE 1392 Query: 185 DVEENTVPYE--VDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIP 242 ++E +P E V ++L ++ G + S ED P+ E+ + Sbjct: 1393 GLKEEGLPEEGSVHGQELSEASSPDG----------------KGSQEDDPVQEEEAGRAS 1436 Query: 243 VTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ 295 +A+P + PP SE P A E+ S +L E GL+ Sbjct: 1437 ASAEPCPAEGTEEPTEPPSHLSETDP----------SASERQSGSQL-EPGLE 1478 Score = 34.3 bits (77), Expect = 1.2 Identities = 47/214 (21%), Positives = 74/214 (34%), Gaps = 29/214 (13%) Query: 138 EEKGEELEQKEKEKEEDTSG---------NTTHSLGAEDTASSQLGFGV-------LELS 181 E +G E + EKE + +T + S GAE + + E+ Sbjct: 1902 ESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVI 1961 Query: 182 QSQDVEENTVPYEVDKEQLQ-----SVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQ 236 +SQ+ EE P D E L+ DV+A A +++ E E Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEE-----EA 2016 Query: 237 SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQI 296 + V AQP + +E ++E V A EA+E+ E + Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG 2076 Query: 297 QKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSRE 330 + PE E + QE + S+G P E Sbjct: 2077 EAHPESEDVDAQE---AEGEAQPESEGVEAPEAE 2107 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 53.1 bits (126), Expect = 3e-06 Identities = 280/1585 (17%), Positives = 538/1585 (33%), Gaps = 290/1585 (18%) Query: 27 IEDSQPESQVLEDDSG--SHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSG 84 +E ++ + +++ D + ++ S H +L + +E+ +VV++ GE D Sbjct: 386 VEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDE-- 443 Query: 85 FNEHLKENKVADPVDSSNLDTCGSISQVIEQLP-------QPNRTSSVLGMSVESAPAVE 137 E K+NK S+ S+ P + + +S + Sbjct: 444 --EKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEK 501 Query: 138 EEK-------GEELEQKEKEKEEDTSGNTTHSLGA-----EDTASSQLGFGVLELSQ--- 182 EE+ E+LE+K K+K E T + T G E++++ L + + Sbjct: 502 EERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLK 561 Query: 183 ------------------SQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 224 S++VEEN+ + +E + S + + ++ +KH Sbjct: 562 ERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHV 621 Query: 225 EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQL 284 +E A + S+ + V + + + +E + M + + K Q+ Sbjct: 622 HAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIME-GVQEETDTRDVKRQV 680 Query: 285 SAQELMESGLQIQKSP---------------------EPEVLSTQEDLFDQSNKTVSSDG 323 E+ Q QKS + EV S++E + KT S D Sbjct: 681 ERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEK--PEREKTPSEDK 738 Query: 324 CSTPSREEGGCSLASTPATTLHLLQLSGQRSL-VQDSLSTNSSDLVAPSPDAFRSTPFIV 382 S + +G C + T LH S ++ L V++++ S S D Sbjct: 739 LSVKHKYKGDCMHKTGDETELH----SSEKGLKVEENIQKQSQQTKLSSDD--------- 785 Query: 383 PSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPP----LLPESTVSPQAS 438 TE++ + SVL ++G + +++ E V EN L E T + S Sbjct: 786 ---KTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKS 842 Query: 439 TPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGD-------------M 485 S S + S H I + S E ++ K D D + Sbjct: 843 RRSSDS-------KIQKDSLGSKQHGITLQRRS--ESYSEDKCDMDSTNMDSNLKPEEVV 893 Query: 486 HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPK--MESLSSHRIDE 543 H + ++ K+ + G + +L ++ + +PK E + E Sbjct: 894 HKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSE 953 Query: 544 DGENTQIED-------TEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDT 596 +++ED EP+ +S + DS + ++ L++ K+ D T Sbjct: 954 KQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDS-----SHRAKLPLAKEKYKSDKDST 1008 Query: 597 DTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEI- 655 TR + L+ G K R S + + E S D ++ E+ Sbjct: 1009 STRLERK-LSDGHKSR---------------SLKHSSKDIKKKDENKS---DDKDGKEVD 1049 Query: 656 KEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKK 715 H G+S +++ CE++ L +E + + T + G LQ+ PKK Sbjct: 1050 SSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQR--PKK 1107 Query: 716 ECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDV 775 + E + IDS + +E+ + + + ++S +D + + Sbjct: 1108 SGDMTLIPEQEPMEIDS-------EPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSA 1160 Query: 776 SCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDS 835 + + E +DS++ AP +P +++ EK ++ L V + + Sbjct: 1161 TVQKDELRTCTADSKA---TAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMN 1217 Query: 836 SQPSLPLVRADDPLRLDQE------LQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKL 889 P+ R + +D E L P ++ +L K A++ + +A Sbjct: 1218 PGEKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNL----KNTAAEEHVAQGDATLE 1273 Query: 890 GKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHST-PIGIS 948 + +S S SS T + D+IP T LE ST P S Sbjct: 1274 HSTNLDSSPSL---SSVTVVPLRESYDPDVIPLFDKRT-------VLEGSTASTSPADHS 1323 Query: 949 NYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASE--E 1006 P ++ V +++T D S +G G D K + K PE + + Sbjct: 1324 ALPNQSLT---VRESEVLKTSD----SKEGGEGFTVDTPAKASITSKRHIPEAHQATLLD 1376 Query: 1007 SLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGN 1066 Q + P G + G E++ + + A++EN+ +E I+ Sbjct: 1377 GKQGKVIMP-LGSKLTGVIVENENITKEGGLVDM------AKKENDLNAEPNLKQTIKAT 1429 Query: 1067 LLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVI------------ 1114 + +K+ + DH + + + +K SP K + Sbjct: 1430 V-------ENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDISIDVERRNENSEV 1482 Query: 1115 -------QGPS-----SPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQ----NNIG 1158 PS + Q E + T +K +T+ E K + P + Sbjct: 1483 DTSAGSGSAPSVLHQRNGQTEDVATGPRRAEKTSVATSTEGKDKDVTLSPVKAGPATTTS 1542 Query: 1159 IQTMECSLRVPET----------------------VSAATQTIKNVCEQGTSTVDQNFGK 1196 +T + + +P T A+ T+ E+G + V + F + Sbjct: 1543 SETRQSEVALPCTSIEADEGLIIGTHSRNNPLHVGAEASECTVFAAAEEGGAVVTEGFAE 1602 Query: 1197 QDA--TVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTL 1254 + T E SGE V+ D L + ++ V ++ Sbjct: 1603 SETFLTSTKEGESGECAVAESEDRAADL-----------------LAVHAVKIEANVNSV 1645 Query: 1255 VTRVITDVYYVDGTEVE-----RKVTEETEEPIVECQECETE--VSPSQTGGSSGDLGDI 1307 VT D G+E + + +E E I E E++ V+ + T +G + Sbjct: 1646 VTEEKDDAVTSAGSEEKCDGSLSRDSEIVEGTITFISEVESDGAVTSAGTEIRAGSISSE 1705 Query: 1308 SSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRG---GPG 1364 S+ + + + + +G+ G+ + +G P + + + G G Sbjct: 1706 EVDGSQGNMMRMGPKKETEGTVTCTGAEGRSDNFVICSVTGAGPREERMVTGAGVVLGDN 1765 Query: 1365 KLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGP 1424 P SQ +GD + G++ VT G G P+ TG+ +++ Sbjct: 1766 DAPPGTSASQ--------EGDGSVNDGTEGESAVTSTGITEDGEGPASCTGSEDSSEGFA 1817 Query: 1425 LGIEDISPNLSPDDKSFSRVVPRVP 1449 + E S D + ++ VP Sbjct: 1818 ISSESEENGESAMDSTVAKEGTNVP 1842 Score = 47.4 bits (111), Expect = 1e-04 Identities = 225/1210 (18%), Positives = 428/1210 (35%), Gaps = 184/1210 (15%) Query: 139 EKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKE 198 EKGE ++KEK+E T HS +EDT + + ++ ++VE +P E + Sbjct: 330 EKGE----RKKEKKEKTEKKFDHSKKSEDTQKVK----DEKQAKEKEVESLKLPSEKNSN 381 Query: 199 QLQSVT-TNSGYTRL-SDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKE 256 + ++V T ++ + SDVD T I D+ E+ +++ VT+ ++ + + Sbjct: 382 KAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSD 441 Query: 257 ------QNPPPARSEDMP---------------------FSPKASVAAMEAKEQLSAQEL 289 QN ++ D +S +E + Q A+E Sbjct: 442 DEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEK 501 Query: 290 MESGLQIQKSPEP-EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQ 348 E L+ Q + E E Q+ +S+KT S E SL A +L+ Sbjct: 502 EERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLK 561 Query: 349 ----------LSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEG-RQDKPM 397 LS +R ++ NS D S + S E+E K + Sbjct: 562 ERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEED---SKETLKTSEHCEKEKISSSKEL 618 Query: 398 DTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPS 457 E +P ++ +S V+ E + STP+ + + Sbjct: 619 KHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKR 678 Query: 458 QPQFSHDIFIPSP-----SLEEQSNDGKKDGDM-HSSSLTVECSKTSEIEP--KNSPEDL 509 Q + S +I P +L+ + + K D + H SL + K+S+ +P + +P + Sbjct: 679 QVERS-EICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSED 737 Query: 510 GLSL-----------TGDSCKLMLS---------------TSEYSQSPKMESLSSHRIDE 543 LS+ TGD +L S ++ S K E S HR +E Sbjct: 738 KLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHR-NE 796 Query: 544 DGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 603 + +D +P+S + ++ E +++ + D +D + Sbjct: 797 RKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLG 856 Query: 604 ILATG--CKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPE 661 G + R E+ +ED C + + S P E + EE + +K Sbjct: 857 SKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKT 916 Query: 662 EGSSGSEVE-EIPE--TPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECS 718 +G VE E+ E T + + KE+N E +++ Q ++ P +E Sbjct: 917 QGKQVKVVETELQEGATKQATTPKPDKEKNTEE-------NDSEKQRKSKVEDKPFEETG 969 Query: 719 EAMEVETSVISIDSPQ-------KLAILDQE-----------LEHKEQEAWEEATSEDSS 760 +ET+ S S Q KL + ++ LE K + + + + SS Sbjct: 970 VEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSS 1029 Query: 761 VVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGD 820 I E E EK + S + C ENR + ++ + E Sbjct: 1030 KDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLC-ENRRGSLSQEMAKGEEK 1088 Query: 821 LKSGTAET---EPVEQDSSQPSLPLVRADDPLRLDQE------LQQPQTQEKTSNSLTED 871 L + T T +++ + L+ +P+ +D E + +TQ+ +N+ +D Sbjct: 1089 LAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQD 1148 Query: 872 SKMANAKQLSS-------------DAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGD 918 N KQ +S D++A + S TL K+ Sbjct: 1149 IDSENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMH 1208 Query: 919 IIPPLTGATPPLIGHLKLEP-KRHSTPIGISNYPESTIATSDVMSESMVETH------DP 971 I ++ P + EP R +T + I + + S V+ + + Sbjct: 1209 IQSAVSKMNPG-----EKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLKNTAAEE 1263 Query: 972 ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESV 1031 + G + ++D L V P E+ + + +K E ST+ A+ Sbjct: 1264 HVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIPLFDKRTVLEGSTASTSPADHS 1323 Query: 1032 ASPQKTMSVLSC----ICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHT 1087 A P ++++V ++++ E + D P + H P + + L+G Sbjct: 1324 ALPNQSLTVRESEVLKTSDSKEGGEGFTVDTPAKASITSKRHIPEA---HQATLLDG--- 1377 Query: 1088 IRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKA 1147 +Q + M P+ ++++ + + +V ++ N + KA Sbjct: 1378 -KQGKVIM--------PLGSKLTGVIVENENITKEGGLVDMAKKENDLNAEPNLKQTIKA 1428 Query: 1148 LIERPSQNNI------GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATV 1201 +E ++ I G+ T + + V + +K++ ++D +++ V Sbjct: 1429 TVENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDI------SIDVERRNENSEV 1482 Query: 1202 QTERGSGEKP 1211 T GSG P Sbjct: 1483 DTSAGSGSAP 1492 Score = 44.3 bits (103), Expect = 0.001 Identities = 254/1269 (20%), Positives = 451/1269 (35%), Gaps = 278/1269 (21%) Query: 127 GMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQ-D 185 G+ + E+E+GE++ E +T LG E GVL ++ D Sbjct: 1853 GIVTSTGAKEEDEEGEDVVTSTGRGNEIGHASTCTGLGEESE-------GVLICESAEGD 1905 Query: 186 VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 245 + TV V+ E ++ + ++VD+ + E+ ++D I S+K I V + Sbjct: 1906 SQIGTVVEHVEAEAGAAIMNANE----NNVDSMSGT---EKGSKDTDICS-SAKGI-VES 1956 Query: 246 QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQE--LMESGL--------- 294 + V E P P E P S A+ ++ QL E + +GL Sbjct: 1957 SVTSAVSGKDEVTPVPGGCE----GPMTSAASDQSDSQLEKVEDTTISTGLVGGSYDVLV 2012 Query: 295 -------------QIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCS-----L 336 +K E + S + + D T +S + + GG + + Sbjct: 2013 SGEVPECEVAHTSPSEKEDEDIITSVENEECDGLMATTASGDITNQNSLAGGKNQGKVLI 2072 Query: 337 ASTPATTLHLLQLSGQRSL---VQDSLSTNSS---------DLVAPSPDAFRSTPFIVPS 384 ST T + Q+S + + D+L T + + AP P A + + Sbjct: 2073 ISTSTTNDYTPQVSAITDVEGGLSDALRTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTA 2132 Query: 385 SPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQS 444 S +E++ + +++S GE F+ + S ++ + V +A+ P+ S Sbjct: 2133 SRSEEKD------ECAMISTSIGEEFELPISSATTIKCAESLQPVAAAVEERATGPVLIS 2186 Query: 445 TPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVEC-SKTSEIEPK 503 T F P+PS P + SP L S + K + + S+S+ EC + S + + Sbjct: 2187 TADFEG---PMPSAPPEAE-----SP-LASTSKEEKDECALISTSIAEECEASVSGVVVE 2237 Query: 504 NSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSK 563 + E G + ++STS +ED E PV S Sbjct: 2238 SENERAGTVMEEKDGSGIISTSS-----------------------VEDCE--GPV--SS 2270 Query: 564 FVPAENDSILMNPAQD-GEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCI 622 VP E + PA++ G+ + T T + + G ++E + + I Sbjct: 2271 AVPQEEGDPSVTPAEEMGDTAMIS---------TSTSEGCEAVMIGAVLQDE---DRLTI 2318 Query: 623 DLTCDSGSQAVPSPATRS-EALSSVLDQEEAMEIKEHHPEEGS--SGSEVEE-------- 671 D A+ S +T +S+ +D+ E ++ +PE S +EV + Sbjct: 2319 TRVEDLSDAAIISTSTAECMPISASIDRHEENQLTADNPEGNGDLSATEVSKHKVPMPSL 2378 Query: 672 IPETPCESQGEEL------------KEENMESVPLHL-SLTETQSQGLCLQKEMPK-KEC 717 I E C G EE +H S + +C +KE KEC Sbjct: 2379 IAENNCRCPGPVRGGKEPGPVLAVSTEEGHNGPSVHKPSAGQGHPSAVCAEKEEKHGKEC 2438 Query: 718 SEAM------EVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSP 771 E + E+++ I++ +K +L+ KE ++ E T+ SS Sbjct: 2439 PEIGPFAGRGQKESTLHLINAEEKNVLLNSL--QKEDKSPETGTAGGSSTASYSAGRGLE 2496 Query: 772 RVDVSCEPLEGVEKCSDSQSWE-------------------DIAPEIEPCAENRLDTKEE 812 S L G E+ S + + D+ P AE+ E+ Sbjct: 2497 GNANSPAHLRGPEQTSGQTAKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQ 2556 Query: 813 KSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDS 872 + E +LK+ T + ++ PS ++ P L P+ ++ + Sbjct: 2557 QGSE--DNLKTSTTKCITGQESKIAPSHTMI---PPATYSVALLAPKCEQDLTIKNDYSG 2611 Query: 873 K---MANAKQLSSDAEAQKLGKP------SAHASQSFCE-SSSETPFHFT---------- 912 K A+A++ D +K + + ++ C+ + E+P + Sbjct: 2612 KWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLK 2671 Query: 913 ----LPKE----GDIIPP---LTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVM 961 +P E G+I+ P L G P I L+ EP + + + N T ++ Sbjct: 2672 MEAYVPSEEEKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRT--NEEIH 2729 Query: 962 SESMVETHDPILGSGKGD-----SGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPA 1016 SES + + SG+ D SG + + D K + P+ + + L + Sbjct: 2730 SESYNKGE---ISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYL-------S 2779 Query: 1017 TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLL-------- 1068 + + + + V +S + + + ++EN E+ P T N Sbjct: 2780 SEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEK 2839 Query: 1069 -HFPSSQGEEEKEKLEGDHTIRQSQQPMKPI-------SPVKDPVSPASQKM-------- 1112 + SS+ EK + D TI+ SQ+ +PI P K PV + Sbjct: 2840 DEYSSSETTGEKPEQNDDDTIK-SQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTG 2898 Query: 1113 ---VIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVP 1169 V Q PSS + + M TD +NKE + L ER N+ G + + S+R Sbjct: 2899 IVTVEQSPSSSKLKVMQTD---------ESNKETAN--LQERSISNDDGEEKIVTSVRRR 2947 Query: 1170 ETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEE 1229 + T+ + DA +K VS P +D + S EEE Sbjct: 2948 GRKPKRSLTVSD----------------DAESSEPERKRQKSVSDPVEDKKEQESDEEEE 2991 Query: 1230 FDMPQPPHG 1238 + P G Sbjct: 2992 EEEEDEPSG 3000 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 53.1 bits (126), Expect = 3e-06 Identities = 189/940 (20%), Positives = 318/940 (33%), Gaps = 169/940 (17%) Query: 232 PIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELME 291 P +Q SK + S H + PP + S+ + +A EQ + Sbjct: 821 PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG---------SITSPQANEQSVTPQRRS 871 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLA-------------- 337 + SP+PE+ S S + STP R+ S + Sbjct: 872 C---FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928 Query: 338 -----STPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPF--IVPSSPTEQE 390 S+P+ + + + +RS S S L+ + S+P + P +P Q Sbjct: 929 SHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS 988 Query: 391 GRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTP---- 446 V ++ P +S P E L+ S + STP Sbjct: 989 HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048 Query: 447 VFPPGSLPIPSQPQFSHD------------IFIPSPSLEEQSNDGKKDGDMHSSSLTVEC 494 F SL + Q Q S D SPSL+ +S K G SSS E Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108 Query: 495 SKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMES-LSSHRIDEDGENTQIEDT 553 + S I +D G E+S SP ++S +S + +++ Sbjct: 1109 ASRSPIR-----QDRG---------------EFSASPMLKSGMSPEQSRFQSDSSSYPTV 1148 Query: 554 EPMSPVLNSKFVPAEN-DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGR 612 + S + S+ AE+ + + + P +D + DK R + S++ K Sbjct: 1149 DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLV---FKDT 1205 Query: 613 EETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS-----GS 667 T + SG+ + P ++ AL + EE ME+ E E S Sbjct: 1206 LRTPPRE-------RSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSS 1258 Query: 668 EVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECS--------E 719 E++E+ + ES E E + L+L ++QSQ E+P S E Sbjct: 1259 ELKEMSTSNFES-----SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPE 1313 Query: 720 AMEVETSVI---SIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS 776 E+ S + S SP + L + + ED + ++ E P +D+ Sbjct: 1314 HKELSNSPLRENSFGSPLEFR-NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDM- 1371 Query: 777 CEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSS 836 K ++S + E+ P A + +S+ + T E+ SS Sbjct: 1372 --------KEQSTRSSGHSSSELSPDAVEKAGMSSNQSI--SSPVLDAVPRTPSRERSSS 1421 Query: 837 QPSLPLVRADDPLRLDQELQQPQTQEKTSNS--LTEDSKMANAKQLSSDAEAQKLGKPSA 894 A P D + P + ++ +S L + S + LS + K + Sbjct: 1422 --------ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473 Query: 895 HASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRH------------- 941 +S C+SS E P+ P + P + + L P+R Sbjct: 1474 SRGRSECDSSPEPKALPQTPR-----PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528 Query: 942 -STPIGISNYPEST-------------IATSDVMSESMVETHDPILGSGKGDSGAAPDVD 987 TP+G + S+ + SD +S +T P+ + SG++P+VD Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPL--RQRSRSGSSPEVD 1586 Query: 988 DKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVAS-----PQKTMSVLS 1042 K +SP S S + + A ++GS + E A P+++ S S Sbjct: 1587 SK-----SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641 Query: 1043 CICEA-RQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEK 1081 E + +E P P + S E K K Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681 Score = 40.0 bits (92), Expect = 0.023 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 7/125 (5%) Query: 370 PSPDAFRSTPFIVPSSPT----EQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 425 PSP RS+ P +PT E+ G +P+ T+ LS+E P + + + ++P Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409 Query: 426 PLLPESTVS---PQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKD 482 LP+S+ S P + P S P P+ SH SP+ + +S+ K Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469 Query: 483 GDMHS 487 HS Sbjct: 470 DKSHS 474 Score = 36.2 bits (82), Expect = 0.33 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 12/106 (11%) Query: 1631 KRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRG-- 1688 KRKRRS+ SS ++ ++SSSSS++ + + S +S S +S SPAK G Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSSSSSSSPSPAKPGPQ 2657 Query: 1689 --RKSATVKPGAVGAGEFVSPCESGDNTGEPSALE----EQRGPLP 1728 K A+ K G SP + D+ + +L E+R P P Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703 Score = 35.8 bits (81), Expect = 0.43 Identities = 69/346 (19%), Positives = 131/346 (37%), Gaps = 32/346 (9%) Query: 823 SGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNS------LTEDSKMAN 876 S +++ + + PS + +A L QP++ ++ S + + + +A Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471 Query: 877 AKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPP-LIGHLK 935 ++ LSS A A H + P P TGA P + L+ Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP------PASTGAQQPSALAALQ 2525 Query: 936 LEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDS-GAAPDVDDKLCLRM 994 +R S+ S+ S+ ++S S S GS DS G++ V ++ L+ Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSS-------GSSSSDSEGSSLPVQPEVALK- 2577 Query: 995 KLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEAR 1054 ++ SP E + +P +RK S++ + S +S + S S + + + Sbjct: 2578 RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637 Query: 1055 SEDPPTTPIRGNLLHFPSSQG----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQ 1110 S ++ P Q K+ G+ R+S+ P KPI ++D S + Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE---RRSRSPRKPIDSLRDSRSLSYS 2694 Query: 1111 KMVIQGPS---SPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPS 1153 + + PS SP+ + + ++ R ++ K E PS Sbjct: 2695 PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740 Score = 33.9 bits (76), Expect = 1.6 Identities = 92/437 (21%), Positives = 148/437 (33%), Gaps = 66/437 (15%) Query: 78 RGDGNSGF---NEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAP 134 RG G +G+ N L + + D + + + + P P+ VE Sbjct: 11 RGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRC 70 Query: 135 AVEEEKGEELEQKEKEKEEDTSGNTTHSL-------GAEDTASSQLGFGVLELSQSQDVE 187 EE EE +E++ +E + L G E+T + V E Q ++ Sbjct: 71 LELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPA--VTETHQLAELN 128 Query: 188 ENTVPYEVDKEQLQSVT-TNSGYTRLSDVDANTAIKHEEQSNEDIP-----IAEQSSKDI 241 E E+L++ + Y S D + +Q + P + E SS Sbjct: 129 EKK------NERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRS 182 Query: 242 PVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPE 301 P Q K K++ RSE SP+ K++ ++ ES + +SP Sbjct: 183 PTPKQKKK-----KKKKDRGRRSESS--SPRRERKKSSKKKKHRSES--ESKKRKHRSPT 233 Query: 302 PEVLSTQEDLFDQSNKTVS----------SDGCSTPSREEGGCSLASTPATTLHLLQLSG 351 P+ +D + +++ + S + S + S + + A H L+G Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293 Query: 352 QRSLVQDSLSTNSSDLVAPSPDAFRS-------TPFIVPSSPTEQEGRQDK------PMD 398 RS S D P + T PSSP E + + K P Sbjct: 294 -RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP 352 Query: 399 TSVLSEEGGEP-----FQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSL 453 + S G EP + G P L PL E P ++P +P P L Sbjct: 353 SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL 412 Query: 454 PIPSQPQFSHDIFIPSP 470 P S + S PSP Sbjct: 413 PQSSSSESSP----PSP 425 Score = 31.6 bits (70), Expect = 8.0 Identities = 49/202 (24%), Positives = 76/202 (37%), Gaps = 23/202 (11%) Query: 1308 SSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEP--ADFALPS------- 1358 SS SS +SS +SS +S S+ SS SSG + G + +P A +PS Sbjct: 2532 SSSSSSSSS---SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588 Query: 1359 --SRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGT 1416 G P + +P K ++ + + + + S ++ + Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648 Query: 1417 RETAVPGPLGI-EDISPNLSPDDKSFSRVVPRVPDSTR--RTDVGAGALRRSDSPEIPFQ 1473 A PGP + + SP P + SR + DS R R+ + RR SP+ Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ---- 2704 Query: 1474 AAAGPSDGLDASSPGNSFVGLR 1495 P D +SS S G R Sbjct: 2705 --PSPRDQQSSSSERGSRRGQR 2724 >gi|62241003 cardiomyopathy associated 5 [Homo sapiens] Length = 4069 Score = 52.8 bits (125), Expect = 3e-06 Identities = 201/967 (20%), Positives = 341/967 (35%), Gaps = 166/967 (17%) Query: 359 SLSTNSSDLVAPSPDAF---RSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQ 415 SL S L A + D + P + E + P SV E+ + + Sbjct: 435 SLEAASPGLAASTQDGLDPDQEQPDLTSIERAEPVSAKLTPTHPSVKGEKEENMLEPSIS 494 Query: 416 SGEPVELENPPLLPESTVSPQASTPISQSTPVFPPG--SLPIPSQPQFSHDIFIPSPSLE 473 EP+ LE P T P A TP + + + L P P S F P S E Sbjct: 495 LSEPLMLEEPEKEEIETSLPIAITPEPEDSNLVEEEIVELDYPESPLVSEKPFPPHMSPE 554 Query: 474 EQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGD-------SCKLMLSTSE 526 + + + + ++S + + E + + G + + + +L E Sbjct: 555 VEHKEEELILPLLAASSPEHVALSEEEREEIASVSTGSAFVSEYSVPQDLNHELQEQEGE 614 Query: 527 YSQSPKMESLSSHRIDEDGENTQIEDTEP-MSPVLNSKFVP------AENDSILMNPAQD 579 +E+++ H + + EN + E P +P S P +EN S L + Sbjct: 615 PVPPSNVEAIAEHAVLSEEENEEFEAYSPAAAPTSESSLSPSTTEKTSENQSPLFSTVTP 674 Query: 580 GEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATR 639 + LS GD+ +GC + T A + +VPS AT+ Sbjct: 675 EYMVLS-------GDEAS--------ESGCYTPDSTSASE-----------YSVPSLATK 708 Query: 640 SEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLT 699 E+L +D++ + +K G IP E G S P LS + Sbjct: 709 -ESLKKTIDRKSPLILK---------GVSEYMIPSEEKEDTGSFTPAVAPASEP-SLSPS 757 Query: 700 ETQSQGLCLQKEMPKKECSEAM------EVETSVISIDSP--QKLAILDQELEHKEQEAW 751 T+ C Q +P SE + ++ + + DS K A + +++ Sbjct: 758 TTEKTSEC-QSPLPSTATSEHVVPSEGEDLGSERFTPDSKLISKYAAPLNATQESQKKII 816 Query: 752 EEATS------EDSSVVIVDVKE----PSPRVDVSCE---PLEGVEKCSDSQSWEDIAPE 798 EA+ + +V+ VD KE SP + V+ E P E S+ Q AP Sbjct: 817 NEASQFKPKGISEHTVLSVDGKEVIGPSSPDLVVASEHSFPPHTTEMTSECQ-----APP 871 Query: 799 IEPCAENRLDTKEEKSVEYEGDLKSGT----------AETEPVEQDSSQPSLPLVRADDP 848 + + +E++VE E S T A E E++ SL L A P Sbjct: 872 LSATPSEYVVLSDEEAVELERYTPSSTSASEFSVPPYATPEAQEEEIVHRSLNLKGASSP 931 Query: 849 LRLDQELQQPQTQEKTSNSLTED-------SKMANAKQLSSDAEAQKLGKPSAHASQSFC 901 + L +E Q+ ++ + ++ A ++ D+ L PS H S Sbjct: 932 MNLSEEDQEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPI-CLTSPSEHTILS-- 988 Query: 902 ESSSETPFHFTLPKEGDI-IPPLTGATPPLIGHLKLEPKRHSTPIGISNYP-ESTIATSD 959 + +E F+ + IPP + +LEP T + S Y S D Sbjct: 989 DEDTEEAELFSPDSASQVSIPPFRISETE---KNELEPDSLLTAVSASGYSCFSEADEED 1045 Query: 960 VMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGE 1019 + S + + S K + P + L + P T+ SE++ + E P T Sbjct: 1046 IGSTAATPVSEQFSSSQKQKAETFPLMSP---LEDLSLPPSTDKSEKA-EIKPEIPTT-- 1099 Query: 1020 RKNGSTAVAE--SVASPQKTMSVLSCICE-----------ARQENEARSE---DPPTTPI 1063 ST+V+E +A QKT + L E + E EA S P P Sbjct: 1100 ----STSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEVEKGEREASSSVAAIPAALPA 1155 Query: 1064 RGNLLHFPSSQGEEEKEKLEGDHTIRQSQQP-----------MKPISPV-KDPVSPAS-- 1109 + +++ + + I++ Q+P +S V K+ + P S Sbjct: 1156 QSSIVKEETKPASPHSVLPDSVPAIKKEQEPTAALTLKAADEQMALSKVRKEEIVPDSQE 1215 Query: 1110 --------QKMVIQGPSSPQGE---AMVTDVLEDQKEG-------RSTNKENPSKALIER 1151 QKM Q P+ P+ E +++ D++++ K+G T++ K Sbjct: 1216 ATAHVSQDQKMEPQPPNVPESEMKYSVLPDMVDEPKKGVKPKLVLNVTSELEQRKLSKNE 1275 Query: 1152 PSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKP 1211 P E SL PE +SA +K+ + T+ + + Q E G Sbjct: 1276 PEVIKPYSPLKETSLSGPEALSAVKMEMKHDSKITTTPIVLHSASSGVEKQVEHGPPALA 1335 Query: 1212 VSAPGDD 1218 SA ++ Sbjct: 1336 FSALSEE 1342 Score = 40.0 bits (92), Expect = 0.023 Identities = 158/796 (19%), Positives = 278/796 (34%), Gaps = 128/796 (16%) Query: 138 EEKGEELEQKEKEKE------EDTSGNTTHSLGAEDTASS-QLGFGVLELSQSQDVEENT 190 E + L E EKE S HS+ +E A + G V++ S SQ +++ Sbjct: 1428 ETSSKHLAWSEAEKEIKFDSLPSVSSIAEHSVLSEVEAKEVKAGLPVIKTSSSQHSDKSE 1487 Query: 191 VPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQ---P 247 DK+ L T D+ + +++S + ++P++ Sbjct: 1488 EARVEDKQDLLFSTV---------CDSERLVSSQKKSLMSTSEVLEPEHELPLSLWGEIK 1538 Query: 248 SKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQI---QKSPEPEV 304 K+ + QN PA +P A+ + + A L + L + + P EV Sbjct: 1539 KKETELPSSQNVSPASKHIIPKGKDEETASSSPELENLASGLAPTLLLLSDDKNKPAVEV 1598 Query: 305 LSTQEDLFDQSNKTVS------------------------SDGCSTPSREEG--GCSLAS 338 ST + F + V+ S+ S R+ G G A Sbjct: 1599 SSTAQGDFPSEKQDVALAELSLEPEKKDKPHQPLELPNAGSEFSSDLGRQSGSIGTKQAK 1658 Query: 339 TPAT-TLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQD--- 394 +P T T + G L + +L A S + P I S +E Q+ Sbjct: 1659 SPITETEDSVLEKGPAELRSREGKEENRELCASS-----TMPAISELSSLLREESQNEEI 1713 Query: 395 KPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI-------SQSTPV 447 KP ++S E EP + G P E + P +S + S P + P+ Sbjct: 1714 KPFSPKIISLESKEPPASVAEGGNPEEFQ-PFTFSLKGLSEEVSHPADFKKGGNQEIGPL 1772 Query: 448 FPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKN--- 504 P G+L + Q DI L E++ G +SS + ++ S+I P + Sbjct: 1773 PPTGNL----KAQVMGDIL---DKLSEET------GHPNSSQVLQSITEPSKIAPSDLLV 1819 Query: 505 SPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKF 564 + +L D + S + S + L + EN +E ++ + Sbjct: 1820 EQKKTEKALHSDQTVKLPDVS--TSSEDKQDLGIKQFSLMRENLPLEQSKSFMTTKPADV 1877 Query: 565 VPAENDSILMNPAQDG------EVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAE 618 + + ++P + E SQ++ + G + L G + A Sbjct: 1878 KETKMEEFFISPKDENWMLGKPENVASQHEQRIAGSVQLDSSSSNELRPG-----QLKAA 1932 Query: 619 DVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCE 678 D TC+ Q +P A S L +EA+ + +S E + Sbjct: 1933 VSSKDHTCEVRKQVLPHSAEESH-----LSSQEAVSALD------TSSGNTETLSSKSYS 1981 Query: 679 SQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAI 738 S+ +L EE P L L + + KE+ SE++ +E + + P K Sbjct: 1982 SEEVKLAEE-----PKSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKED- 2035 Query: 739 LDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIA-- 796 QE E + + SV V + S V + P EGVE ++ + Sbjct: 2036 -SQEKIKLPPERFFQKPVSGLSVEQVKSETISSSVKTAHFPAEGVEPALGNEKEAHRSTP 2094 Query: 797 --PEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQE 854 PE +P E+++ + K ++ D G + V+ + + + + A +P Sbjct: 2095 PFPEEKPLEESKM--VQSKVID---DADEGKKPSPEVKIPTQRKPISSIHAREP------ 2143 Query: 855 LQQPQTQEKTSNSLTE 870 Q P++ E T N T+ Sbjct: 2144 -QSPESPEVTQNPPTQ 2158 Score = 37.4 bits (85), Expect = 0.15 Identities = 223/1167 (19%), Positives = 414/1167 (35%), Gaps = 227/1167 (19%) Query: 136 VEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQL------------GFGVLELSQS 183 VEE KG ++ E +++ T+ + E+T + + + E Sbjct: 2414 VEESKGSLIDFSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVL 2473 Query: 184 QDVEENTVPYEV-DKEQL--QSVTTNSGYTRLSDVDANTAIKH---EEQSNEDIPI---- 233 + + + P E+ D ++ +T S T L + A+ +H E NE I Sbjct: 2474 AEKQNSVAPLELRDSNEIGKTQITLGSRSTELKESKADAMPQHFYQNEDYNERPKIIVGS 2533 Query: 234 ----AEQSSKDIPVTAQPSK-DVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQE 288 E+ + V ++ K H N + S + S S+ ++ + A Sbjct: 2534 EKEKGEEKENQVYVLSEGKKQQEHQPYSVNVAESMSRESDISLGHSLGETQSFSLVKATS 2593 Query: 289 LMESGLQIQKSPEPEV-----LSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATT 343 + E + PE+ + TQ ++S V P +A + Sbjct: 2594 VTEKSEAMLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLP--------VALSCRDE 2645 Query: 344 LHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPF-----IVPSSPTEQEGRQDKPMD 398 + LS + +LV + S + D + + FR + + + T ++G Q+K + Sbjct: 2646 IENHSLSQEGNLVLEKSSRDMPD-HSEEKEQFRESELSKGGSVDITKETVKQGFQEKAVG 2704 Query: 399 TSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQ 458 T E + +K ++ PV L + ++S + + + +S+ P S + Sbjct: 2705 TQPRPLEESKVLVEKTKTFLPVVLSCHDEIENHSLSQEGNLVLEKSSRDMPDHS---EEK 2761 Query: 459 PQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTV----ECSKTSEIEP----KNSPEDL- 509 QF S++ K+ S T+ + +K+SE P P+ L Sbjct: 2762 EQFKESELWKGGSVDITKESMKEGFPSKESERTLARPFDETKSSETPPYLLSPVKPQTLA 2821 Query: 510 -GLSLTGDSCK------------------LMLSTSEYSQSPKMESLSSHRIDEDGENTQI 550 G S ++ K + S + S PK L S E E+T++ Sbjct: 2822 SGASPEINAVKKKEMPRSELTPERHTVHTIQTSKDDTSDVPKQSVLVSKHHLEAAEDTRV 2881 Query: 551 EDTEPMSPVLN--SKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATG 608 + EP+S + ++F+ + S + E+ D KG+D + L+ Sbjct: 2882 K--EPLSSAKSNYAQFISNTSASNADKMVSNKEMPKEPEDTYAKGEDFTVTSKPAGLSED 2939 Query: 609 CKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEA--MEIKEHHPEEGSSG 666 K ++E C+ + P A S +DQEE+ M+ K + EE +S Sbjct: 2940 QKTAFSIISEG------CEILNIHAP-------AFISSIDQEESEQMQDKLEYLEEKAS- 2985 Query: 667 SEVEEIPETPCESQGEELKEENMESVPLHLSL-TETQSQGLCLQKEMPKKECSEAMEVET 725 + IP ++ E+V H +L + + + + KE +KE + E Sbjct: 2986 --FKTIP-----------LPDDSETVACHKTLKSRLEDEKVTPLKENKQKETHKTKE--- 3029 Query: 726 SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 785 IS DS L+ + + E++ +E+ T D ++ P P + + L EK Sbjct: 3030 -EISTDSETDLSFIQPTIP-SEEDYFEKYTLIDYNI------SPDPEKQKAPQKLNVEEK 3081 Query: 786 CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 845 S + E I+ + + E ++E+E DL V+ D S Sbjct: 3082 LSKEVTEETISFPV---------SSVESALEHEYDL---------VKLDES--------F 3115 Query: 846 DDPLRLDQELQQPQTQEKTS--NSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCES 903 P + L P+TQ + S ++++D+K D +++ G P A + Sbjct: 3116 YGPEKGHNILSHPETQSQNSADRNVSKDTK--------RDVDSKSPGMPLFEAEEGVLSR 3167 Query: 904 SSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSD-VMS 962 + P +I P PP + L + + +G E T + D V S Sbjct: 3168 TQ------IFPTTIKVIDPEFLEEPPALAFLYKD--LYEEAVGEKKKEEETASEGDSVNS 3219 Query: 963 ESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKN 1022 E+ + + G G +K L+ ++ +T +++ LE E++ Sbjct: 3220 EASFPSRNSDTDDGTG------IYFEKYILKDDILH-DTSLTQKDQGQGLE-----EKRV 3267 Query: 1023 GSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKL 1082 G + +A+ + IC + E + GE E Sbjct: 3268 GKDDSYQPIAAEGEIWGKFGTICREKSLEEQK-----------------GVYGEGESV-- 3308 Query: 1083 EGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKE 1142 DH M+ +P+ + V A+QK+ P VLE E S Sbjct: 3309 --DHVETVGNVAMQKKAPITEDVRVATQKISYAVPFED-----THHVLERADEAGSHG-- 3359 Query: 1143 NPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQ 1202 N +G + E +L VP VS + + G + V + ++ + Sbjct: 3360 ------------NEVGNASPEVNLNVPVQVSFPEEEFAS----GATHVQETSLEEPKILV 3403 Query: 1203 TERGSGEKPVSAPGDD----TESLHSQ 1225 S E+ ++P D TESLH++ Sbjct: 3404 PPEPSEERLRNSPVQDEYEFTESLHNE 3430 Score = 33.5 bits (75), Expect = 2.1 Identities = 45/225 (20%), Positives = 84/225 (37%), Gaps = 22/225 (9%) Query: 138 EEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDK 197 +EK + E+ +K+K E H L + DTA L V E + + T E+++ Sbjct: 3604 DEKAQSFEEVKKKKMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINE 3663 Query: 198 EQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQ 257 L ++ + + ++ A + +H + S+ ++Q K + V Sbjct: 3664 RLLSAMESTASLEKMP--AAFSLFEHYDDSSAR---SDQMLKQVAV-------------- 3704 Query: 258 NPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK 317 P P R E P P ++ + A +E + Q+ EP+ +L ++ Sbjct: 3705 -PQPPRLE--PQEPNSATSTTIAVYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRL 3761 Query: 318 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLST 362 TV C E C A L +R++ + + ST Sbjct: 3762 TVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTAPST 3806 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 51.2 bits (121), Expect = 1e-05 Identities = 70/330 (21%), Positives = 133/330 (40%), Gaps = 42/330 (12%) Query: 190 TVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSK 249 T+ ++ K ++++ + + ++ T ++ E+ E+ A ++++ V+ + K Sbjct: 431 TISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTA--ITEELAVSMKEEK 488 Query: 250 DVHVVKEQNPPPARSEDMPFSPK-ASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQ 308 +++ P A E++ A E KE+ +E E Q ++ E E + Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG--QEEEEEEDEGAKSD 546 Query: 309 EDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLS--TNSSD 366 + S K SS+ +EEG T A + + V++ + Sbjct: 547 QAEEGGSEKEGSSE------KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600 Query: 367 LVAPS----PDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVEL 422 LVA + P+ +S VP SP E++G+ P+ S + E+G P K PVE Sbjct: 601 LVADAKVEKPEKAKSP---VPKSPVEEKGKS--PVPKSPVEEKGKSPVPKS-----PVEE 650 Query: 423 ENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKD 482 + +P+S V + +P+S+S PV P+P P + ++ GK + Sbjct: 651 KGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVPKS---------PVEEAKSKAEVGKGE 700 Query: 483 GDMHSSSLTVECSKTSEIE-----PKNSPE 507 E K ++E PK+ PE Sbjct: 701 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 730 Score = 42.4 bits (98), Expect = 0.005 Identities = 96/469 (20%), Positives = 165/469 (35%), Gaps = 72/469 (15%) Query: 711 EMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS 770 E K E EA+ T +++ ++ + E KE+E EA E+ + VK + Sbjct: 463 EDEKSEMEEALTAITEELAVSMKEEKK---EAAEEKEEEP--EAEEEEVAAKKSPVKATA 517 Query: 771 PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEP 830 P V EG ++ + Q E E + + E G K G++E E Sbjct: 518 PEVKEE----EGEKEEEEGQEEE----------EEEDEGAKSDQAEEGGSEKEGSSEKEE 563 Query: 831 VEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDS-KMANAKQLSSDAEAQKL 889 EQ+ + + E + + + K + E S ++A ++L +DA+ +K Sbjct: 564 GEQEEGE-------------TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610 Query: 890 GKPSAHASQSFCESSSETPF-HFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGIS 948 K + +S E ++P + ++G P + + P +S Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 670 Query: 949 NYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESL 1008 P A S V +S VE GKG+ + + K EE + Sbjct: 671 KSPVEEKAKSPV-PKSPVEEAKSKAEVGKGEQKEEEEKEVK-----------EAPKEEKV 718 Query: 1009 QFNLEKPA-TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNL 1067 + EKP E+K + V E + T ++ + E E + E P Sbjct: 719 EKKEEKPKDVPEKKKAESPVKEEAVAEVVT---ITKSVKVHLEKETKEEGKPL------- 768 Query: 1068 LHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVT 1127 Q E+EKEK G+ + D + S+K I +G+ V Sbjct: 769 ------QQEKEKEKAGGEGGSEEEG---------SDKGAKGSRKEDIAVNGEVEGKEEVE 813 Query: 1128 DVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAAT 1176 +++ GR K + L P+ G E + V +TV T Sbjct: 814 QETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 862 Score = 39.7 bits (91), Expect = 0.030 Identities = 93/426 (21%), Positives = 150/426 (35%), Gaps = 70/426 (16%) Query: 613 EETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI 672 EET ED S + + T A+S +++EA E KE PE +E EE+ Sbjct: 458 EETKVEDE------KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE-----AEEEEV 506 Query: 673 P--ETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE--AMEVETSVI 728 ++P ++ E+KEE E E + + E K + +E E E S Sbjct: 507 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE------EDEGAKSDQAEEGGSEKEGSSE 560 Query: 729 SIDSPQKLAILDQELEHKEQEAWEEATSEDSS-------VVIVDVKEPSPRVDVSCEPLE 781 + Q+ + E E +E EA EE E+ S ++ D K P S P Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620 Query: 782 GVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLP 841 VE+ S P+ P E + VE +G PVE+ P Sbjct: 621 PVEEKGKSP-----VPK-SPVEEKGKSPVPKSPVEEKG---KSPVPKSPVEEKGKSPV-- 669 Query: 842 LVRADDPLRLDQELQQPQTQEKTSNSLTE----DSKMANAKQLSSDAEAQKLGKPSAHAS 897 + P+ + P++ + + S E + K K++ + +K+ K Sbjct: 670 ---SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPK 726 Query: 898 QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 957 + +E+P + + + + T + HL+ E K P+ E Sbjct: 727 DVPEKKKAESPV------KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGE 780 Query: 958 SDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPAT 1017 E GS KG G+ + V+ E E EE Q EK + Sbjct: 781 GGSEEE----------GSDKGAKGSRKE--------DIAVNGEVEGKEEVEQETKEKGSG 822 Query: 1018 GERKNG 1023 E + G Sbjct: 823 REEEKG 828 Score = 35.0 bits (79), Expect = 0.73 Identities = 39/186 (20%), Positives = 75/186 (40%), Gaps = 14/186 (7%) Query: 132 SAPAVEEEKG----EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVE 187 +AP V+EE+G EE +++E+E++E + G+E SS+ G E +++ Sbjct: 516 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 575 Query: 188 ENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI---PIAEQSSKDIPVT 244 E KE+ + + ++ A+ ++ E++ + P+ E+ +P + Sbjct: 576 EGEEAEA--KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS 633 Query: 245 AQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ-IQKSPEPE 303 K V + +P SP + K +S + E + KSP E Sbjct: 634 PVEEKGKSPVPKSPVEEKGKSPVPKSP----VEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689 Query: 304 VLSTQE 309 S E Sbjct: 690 AKSKAE 695 Score = 32.7 bits (73), Expect = 3.6 Identities = 47/240 (19%), Positives = 98/240 (40%), Gaps = 27/240 (11%) Query: 109 ISQVIEQLPQPNRTS----SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLG 164 + ++IE+ + S ++ ++ E A +++EEK E E+KE+E E + Sbjct: 453 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 512 Query: 165 AEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 224 + TA E+ + + +E E ++E+ + ++ S+ + ++ K E Sbjct: 513 VKATAP--------EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE-KEE 563 Query: 225 EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQL 284 + E AE ++ +K+ V+E++ A E++ K +AK + Sbjct: 564 GEQEEGETEAEAEGEE-----AEAKEEKKVEEKSEEVATKEELVADAKVE-KPEKAKSPV 617 Query: 285 SAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCS----TPSREEGGCSLASTP 340 + E G KSP P+ ++ V G S +P E+G ++ +P Sbjct: 618 PKSPVEEKG----KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 673 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 51.2 bits (121), Expect = 1e-05 Identities = 70/330 (21%), Positives = 133/330 (40%), Gaps = 42/330 (12%) Query: 190 TVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSK 249 T+ ++ K ++++ + + ++ T ++ E+ E+ A ++++ V+ + K Sbjct: 55 TISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTA--ITEELAVSMKEEK 112 Query: 250 DVHVVKEQNPPPARSEDMPFSPK-ASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQ 308 +++ P A E++ A E KE+ +E E Q ++ E E + Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG--QEEEEEEDEGAKSD 170 Query: 309 EDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLS--TNSSD 366 + S K SS+ +EEG T A + + V++ + Sbjct: 171 QAEEGGSEKEGSSE------KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 224 Query: 367 LVAPS----PDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVEL 422 LVA + P+ +S VP SP E++G+ P+ S + E+G P K PVE Sbjct: 225 LVADAKVEKPEKAKSP---VPKSPVEEKGKS--PVPKSPVEEKGKSPVPKS-----PVEE 274 Query: 423 ENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKD 482 + +P+S V + +P+S+S PV P+P P + ++ GK + Sbjct: 275 KGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVPKS---------PVEEAKSKAEVGKGE 324 Query: 483 GDMHSSSLTVECSKTSEIE-----PKNSPE 507 E K ++E PK+ PE Sbjct: 325 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 354 Score = 42.4 bits (98), Expect = 0.005 Identities = 96/469 (20%), Positives = 165/469 (35%), Gaps = 72/469 (15%) Query: 711 EMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS 770 E K E EA+ T +++ ++ + E KE+E EA E+ + VK + Sbjct: 87 EDEKSEMEEALTAITEELAVSMKEEKK---EAAEEKEEEP--EAEEEEVAAKKSPVKATA 141 Query: 771 PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEP 830 P V EG ++ + Q E E + + E G K G++E E Sbjct: 142 PEVKEE----EGEKEEEEGQEEE----------EEEDEGAKSDQAEEGGSEKEGSSEKEE 187 Query: 831 VEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDS-KMANAKQLSSDAEAQKL 889 EQ+ + + E + + + K + E S ++A ++L +DA+ +K Sbjct: 188 GEQEEGE-------------TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234 Query: 890 GKPSAHASQSFCESSSETPF-HFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGIS 948 K + +S E ++P + ++G P + + P +S Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 294 Query: 949 NYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESL 1008 P A S V +S VE GKG+ + + K EE + Sbjct: 295 KSPVEEKAKSPV-PKSPVEEAKSKAEVGKGEQKEEEEKEVK-----------EAPKEEKV 342 Query: 1009 QFNLEKPA-TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNL 1067 + EKP E+K + V E + T ++ + E E + E P Sbjct: 343 EKKEEKPKDVPEKKKAESPVKEEAVAEVVT---ITKSVKVHLEKETKEEGKPL------- 392 Query: 1068 LHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVT 1127 Q E+EKEK G+ + D + S+K I +G+ V Sbjct: 393 ------QQEKEKEKAGGEGGSEEEG---------SDKGAKGSRKEDIAVNGEVEGKEEVE 437 Query: 1128 DVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAAT 1176 +++ GR K + L P+ G E + V +TV T Sbjct: 438 QETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 486 Score = 39.7 bits (91), Expect = 0.030 Identities = 93/426 (21%), Positives = 150/426 (35%), Gaps = 70/426 (16%) Query: 613 EETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI 672 EET ED S + + T A+S +++EA E KE PE +E EE+ Sbjct: 82 EETKVEDE------KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE-----AEEEEV 130 Query: 673 P--ETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE--AMEVETSVI 728 ++P ++ E+KEE E E + + E K + +E E E S Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE------EDEGAKSDQAEEGGSEKEGSSE 184 Query: 729 SIDSPQKLAILDQELEHKEQEAWEEATSEDSS-------VVIVDVKEPSPRVDVSCEPLE 781 + Q+ + E E +E EA EE E+ S ++ D K P S P Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244 Query: 782 GVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLP 841 VE+ S P+ P E + VE +G PVE+ P Sbjct: 245 PVEEKGKSP-----VPK-SPVEEKGKSPVPKSPVEEKG---KSPVPKSPVEEKGKSPV-- 293 Query: 842 LVRADDPLRLDQELQQPQTQEKTSNSLTE----DSKMANAKQLSSDAEAQKLGKPSAHAS 897 + P+ + P++ + + S E + K K++ + +K+ K Sbjct: 294 ---SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPK 350 Query: 898 QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 957 + +E+P + + + + T + HL+ E K P+ E Sbjct: 351 DVPEKKKAESPV------KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGE 404 Query: 958 SDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPAT 1017 E GS KG G+ + V+ E E EE Q EK + Sbjct: 405 GGSEEE----------GSDKGAKGSRKE--------DIAVNGEVEGKEEVEQETKEKGSG 446 Query: 1018 GERKNG 1023 E + G Sbjct: 447 REEEKG 452 Score = 35.0 bits (79), Expect = 0.73 Identities = 39/186 (20%), Positives = 75/186 (40%), Gaps = 14/186 (7%) Query: 132 SAPAVEEEKG----EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVE 187 +AP V+EE+G EE +++E+E++E + G+E SS+ G E +++ Sbjct: 140 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 199 Query: 188 ENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI---PIAEQSSKDIPVT 244 E KE+ + + ++ A+ ++ E++ + P+ E+ +P + Sbjct: 200 EGEEAEA--KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS 257 Query: 245 AQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ-IQKSPEPE 303 K V + +P SP + K +S + E + KSP E Sbjct: 258 PVEEKGKSPVPKSPVEEKGKSPVPKSP----VEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313 Query: 304 VLSTQE 309 S E Sbjct: 314 AKSKAE 319 Score = 32.7 bits (73), Expect = 3.6 Identities = 47/240 (19%), Positives = 98/240 (40%), Gaps = 27/240 (11%) Query: 109 ISQVIEQLPQPNRTS----SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLG 164 + ++IE+ + S ++ ++ E A +++EEK E E+KE+E E + Sbjct: 77 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 136 Query: 165 AEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 224 + TA E+ + + +E E ++E+ + ++ S+ + ++ K E Sbjct: 137 VKATAP--------EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE-KEE 187 Query: 225 EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQL 284 + E AE ++ +K+ V+E++ A E++ K +AK + Sbjct: 188 GEQEEGETEAEAEGEE-----AEAKEEKKVEEKSEEVATKEELVADAKVE-KPEKAKSPV 241 Query: 285 SAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCS----TPSREEGGCSLASTP 340 + E G KSP P+ ++ V G S +P E+G ++ +P Sbjct: 242 PKSPVEEKG----KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 297 >gi|148806908 fibronectin type III domain containing 1 [Homo sapiens] Length = 1894 Score = 51.2 bits (121), Expect = 1e-05 Identities = 154/667 (23%), Positives = 242/667 (36%), Gaps = 91/667 (13%) Query: 838 PSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQK--LGKPSAH 895 P P +RA LD + + +E+ + EDS M+ SD + QK L PS H Sbjct: 520 PRKPQLRAKKAEELDLQSTEITGEEELGSR--EDSPMS-----PSDTQDQKRTLRPPSRH 572 Query: 896 ASQSFCESSSETPFHF-TLPK-EGDIIPPLTGATPPLIG---HLKLEPKRHSTPIGISNY 950 + LP+ EG P + AT P G P H++ G S+ Sbjct: 573 GHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSASASPAHHASTQGTSHR 632 Query: 951 PESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQF 1010 P + +D +V++ + G A + L SP + + S Sbjct: 633 PSLPASLND---NDLVDSDEDERAVGSLHPKGA-FAQPRPALSPSRQSPSSVLRDRSSVH 688 Query: 1011 NLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHF 1070 KPA+ R+ + AE +S S LS + S PT P L Sbjct: 689 PGAKPASPARRTPHSGAAEEDSSASAPPSRLS------PPHGGSSRLLPTQPH----LSS 738 Query: 1071 PSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVL 1130 P S+G ++ E ++ S+ M S V +S +Q V +G + GE+ Sbjct: 739 PLSKGGKDGEDAPATNSNAPSRSTMS--SSVSSHLSSRTQ--VSEGAEASDGESHG---- 790 Query: 1131 EDQKEGRSTNKENPSKALIERPSQNNIGI---QTMECSLRVPETVSAATQTIKNVCEQGT 1187 + +E E ++ L RP+ + + + + R P S Sbjct: 791 DGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQ 850 Query: 1188 STVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRT 1247 STV A + S P + G +H G+EE + P P V++ H+ + Sbjct: 851 STVPSR-----AHPRVPSHSDSHPKLSSG-----IH--GDEEDEKPLP--ATVVNDHVPS 896 Query: 1248 IREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDI 1307 R ++R D+ +R + +EPI E +P TG + G Sbjct: 897 --SSRQPISRGWEDLR----RSPQRGASLHRKEPIPE--------NPKSTGADTHPQGKY 942 Query: 1308 SSFSSKASSLHRTSSGTS--LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGK 1365 SS +SKA + +++ + S GS+ + A P R + ++ PS P + Sbjct: 943 SSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQH----PSV---PRR 995 Query: 1366 LSP-RKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPR------GRGR---RGRPPSRT-- 1413 ++P R Q PV G R G++P PR GR R +GR S + Sbjct: 996 MTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDP 1055 Query: 1414 -TGTRETAVPGPLGIEDISPNLSPDDKSFSRVVP--RVPDSTRRTDVGAGALRRSDSPEI 1470 T + +P L +D S DD S R P R A +L + E Sbjct: 1056 YTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVES 1115 Query: 1471 PFQAAAG 1477 P A AG Sbjct: 1116 PTGAGAG 1122 >gi|226437579 NAC alpha domain containing [Homo sapiens] Length = 1562 Score = 49.7 bits (117), Expect = 3e-05 Identities = 126/654 (19%), Positives = 223/654 (34%), Gaps = 83/654 (12%) Query: 64 LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 123 ++V + AGEE D +G + + P + G S E+LP P + Sbjct: 496 VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553 Query: 124 SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 183 S L + +S ++EE G +L K + T A++ + + Sbjct: 554 S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608 Query: 184 QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 243 QD + ++ P V + S G T D + ++ P ++ + Sbjct: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668 Query: 244 TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 291 A+ + PP P + D+ +PK A++ + +A+E L+ + L Sbjct: 669 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 347 + +P+P +T + T+ D TP L+S P A T+ Sbjct: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788 Query: 348 QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 407 Q +L QDS T +P T+ +++S++ Sbjct: 789 QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831 Query: 408 EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPV---------FPPGSLPIPSQ 458 E S PPL + T A P++ +TPV P S P Sbjct: 832 EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPL 886 Query: 459 PQFSHDIFI---PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 515 P D+ P + S ++ + S + P + PE L ++ Sbjct: 887 PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP- 945 Query: 516 DSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILM 574 +E +P E +++ E GE E + L + PA D + Sbjct: 946 -----QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 1000 Query: 575 N---PAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDL 624 + PA + + +D D T + +S L G E +AE + C++ Sbjct: 1001 DDPQPAAEAGTPWAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEA 1056 Query: 625 TCDSGSQAVPSPATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 676 +G A P + + E L QE ++ +EH P G+ E+P+ P Sbjct: 1057 RAHTGDGAKPD-SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1107 Score = 47.0 bits (110), Expect = 2e-04 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%) Query: 355 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 410 L+ + LS+ + AP P P IV T Q + T++ +EGG +P Sbjct: 95 LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152 Query: 411 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 467 + G+ + + +PP P+S +P STP + + P P S+ + D + Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209 Query: 468 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 526 SP + DGD +SS + S + E + P GLS G + L + Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269 Query: 527 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 566 + P E SLS+ G+ D + ++ P++ + +P Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329 Query: 567 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 622 E + + +P G++ +D T + D+SI +G +E A D Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385 Query: 623 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 669 + DS S + + AT + ++E K ++G+ V Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445 Query: 670 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 719 E P+T SQ +EL E E + L T T + LQ E+ + + Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505 Query: 720 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 779 A E ET DS + QE E ++S + K P+P+ + S Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557 Query: 780 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 838 + + D+ +P A + ++ K + L +A T P+ QD+ Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614 Query: 839 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 898 S P P+ + Q Q + +L +DS M L D E KP A A+ Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665 Query: 899 SFCESSSETPFHFTLPKEGDIIPPL 923 S + TLP++ + PPL Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686 Score = 40.8 bits (94), Expect = 0.013 Identities = 216/1053 (20%), Positives = 358/1053 (33%), Gaps = 207/1053 (19%) Query: 225 EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 280 E + E + + ++S+ + P T Q P V V P E D +++ AM Sbjct: 467 EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526 Query: 281 KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 338 Q E++ + + +K P P+ ++++ T+ D +EEGG L S Sbjct: 527 PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576 Query: 339 ---TPATTLHLLQLSGQRSLVQDSLST-----NSSDLV-APSPDAFRSTPFIVPSSPTEQ 389 A T+ Q +L QDS T +DL AP P A + S + Sbjct: 577 RKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV-----SQQAE 631 Query: 390 EGR---QDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI----- 441 EG QD M + P Q S P P+ + VS QA + Sbjct: 632 EGLTLPQDSVMTPPL-------PLQDTELSSAP-----KPVAAATLVSQQAEEGLTLPQD 679 Query: 442 SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEE-----QSNDGKKDGDMHSSSLTVECSK 496 S TP P + S P+ + S EE Q + + + L+ Sbjct: 680 SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 739 Query: 497 TSEIEPKNSPEDLGLSLTGDSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT 553 + + + GL+L DS L L ++ S +PK + ++ + E + Sbjct: 740 VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 799 Query: 554 EPMSPVL-------NSKFVPAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDIS 603 M+P L +S P +I+ A++G + L Q+ T DTD Sbjct: 800 SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPK 858 Query: 604 ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 663 +A ++ AE+ LT S P + LSS A EEG Sbjct: 859 PVAAATPVSQQ--AEE---GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEG 913 Query: 664 SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKE------------ 711 + +P+ + L++ S P L++ Q+ LQ E Sbjct: 914 LT------LPQDSAMTAPLPLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVAT 963 Query: 712 MPKKECSEAM-------EVETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSV 761 M ++E EA+ E ++ ++ P L + Q+ EA W DS++ Sbjct: 964 MAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023 Query: 762 VIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDL 821 + + P P E E + + P E C E R T + + Sbjct: 1024 GMEALSLPEPASGAGEEIAEALSR-----------PGREACLEARAHTGDGAKPD----- 1067 Query: 822 KSGTAETEPVEQDSSQPSLPLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQL 880 S ET VE PL + P L + P +++ ++ A++ Sbjct: 1068 -SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREE 1126 Query: 881 S--SDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEP 938 S + PSA A+++ +S E+ GA L P Sbjct: 1127 RGLSGKSTPEPTLPSAVATEASLDSCPESS---------------VGAVSSLDRGCPDAP 1171 Query: 939 KRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLV 997 S P S PE P+LG G + P V L L+ Sbjct: 1172 APTSAPT--SQQPE------------------PVLGLGSVEQPHEVPSV-----LGTPLL 1206 Query: 998 SPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSED 1057 P ++ +++P G + +A + P + + C+C+ QE+ E+ Sbjct: 1207 QPPENLAKGQPSTPVDRPL-GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEE 1263 Query: 1058 PPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQP---MKPISPVKDP---------- 1104 PP G+L P G + T P + P SP+ P Sbjct: 1264 PP-----GSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDL 1318 Query: 1105 ---VSPASQKMVIQGPSSPQGEAMVT--------DVLEDQKE---GRSTNKENPSKALIE 1150 + P Q GP SP G ++ D LE+ G + ++ ++ E Sbjct: 1319 ALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAE 1378 Query: 1151 RPSQNNIGIQTMECSLRVP-----ETVSAATQT 1178 Q+ + QT++C + P ET++ A Q+ Sbjct: 1379 LDEQDILAPQTVQCPAQAPAGGSEETIAKAKQS 1411 Score = 32.3 bits (72), Expect = 4.7 Identities = 124/651 (19%), Positives = 237/651 (36%), Gaps = 91/651 (13%) Query: 636 PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEE--LKEENMESVP 693 PA S++ Q EA+E+ PEE + + P +GEE ++S+ Sbjct: 307 PAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLS 366 Query: 694 LHLSLTETQSQGLCLQKE-----MPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQ 748 LS+TE + + + S A + + S + + +L ++ E+ Sbjct: 367 -DLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE 425 Query: 749 EAWEEA---TSEDSSV--VIVDVKEPSPRVDVSCEPLEGVEKCSD------SQSWEDIAP 797 E+ A ++D +V + + S R + E + + ++ +S + P Sbjct: 426 ESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTP 485 Query: 798 ---EIEPCAENRLDTK-EEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQ 853 ++ P + + T+ ++ E E D +G SQ + + + + + Sbjct: 486 HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAE- 544 Query: 854 ELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTL 913 + P QE+TS +L DS ++ D + + KP A A+ ++ + TL Sbjct: 545 --KLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR--KPVAAATIVPRQAKED----LTL 596 Query: 914 PKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPES--TIATSDVMSESMVETHDP 971 P++ + PPL P L PK + +S E T+ VM+ + Sbjct: 597 PQDSAMTPPL----PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPL------ 646 Query: 972 ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESV 1031 P D +L K V+ T S+++ + L P + Sbjct: 647 ------------PLQDTELSSAPKPVAAATLVSQQA-EEGLTLPQDSAMTPPLPLQDTDL 693 Query: 1032 ASPQKTMSVLSCICEARQENEARSED---PPTTPIRGNLLHF---PSSQGEEEKEKLEGD 1085 +S K ++ + + + +E +D P P++ L P + ++ E Sbjct: 694 SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEG 753 Query: 1086 HTIRQSQQPMKPISPVKD--------PVSPAS--QKMVIQGPSSPQGEAMVTDVLEDQKE 1135 T+ Q M P P++D PV+ A+ + +G + PQ AM + + Sbjct: 754 LTLPQ-DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812 Query: 1136 GRSTNKENPSKALIERPSQNN------------IGIQTMECSLRVPETVSAATQTIKNVC 1183 S K + ++ + ++ + +Q + S P+ V+AAT + Sbjct: 813 LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAE 871 Query: 1184 EQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQ 1234 E T D T+ S KPV+A + Q EE +PQ Sbjct: 872 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA----ATPVSQQAEEGLTLPQ 918 >gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] Length = 1562 Score = 49.7 bits (117), Expect = 3e-05 Identities = 126/654 (19%), Positives = 223/654 (34%), Gaps = 83/654 (12%) Query: 64 LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 123 ++V + AGEE D +G + + P + G S E+LP P + Sbjct: 496 VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553 Query: 124 SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 183 S L + +S ++EE G +L K + T A++ + + Sbjct: 554 S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608 Query: 184 QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 243 QD + ++ P V + S G T D + ++ P ++ + Sbjct: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668 Query: 244 TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 291 A+ + PP P + D+ +PK A++ + +A+E L+ + L Sbjct: 669 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 347 + +P+P +T + T+ D TP L+S P A T+ Sbjct: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788 Query: 348 QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 407 Q +L QDS T +P T+ +++S++ Sbjct: 789 QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831 Query: 408 EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPV---------FPPGSLPIPSQ 458 E S PPL + T A P++ +TPV P S P Sbjct: 832 EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPL 886 Query: 459 PQFSHDIFI---PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 515 P D+ P + S ++ + S + P + PE L ++ Sbjct: 887 PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP- 945 Query: 516 DSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILM 574 +E +P E +++ E GE E + L + PA D + Sbjct: 946 -----QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 1000 Query: 575 N---PAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDL 624 + PA + + +D D T + +S L G E +AE + C++ Sbjct: 1001 DDPQPAAEAGTPWAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEA 1056 Query: 625 TCDSGSQAVPSPATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 676 +G A P + + E L QE ++ +EH P G+ E+P+ P Sbjct: 1057 RAHTGDGAKPD-SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1107 Score = 47.0 bits (110), Expect = 2e-04 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%) Query: 355 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 410 L+ + LS+ + AP P P IV T Q + T++ +EGG +P Sbjct: 95 LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152 Query: 411 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 467 + G+ + + +PP P+S +P STP + + P P S+ + D + Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209 Query: 468 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 526 SP + DGD +SS + S + E + P GLS G + L + Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269 Query: 527 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 566 + P E SLS+ G+ D + ++ P++ + +P Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329 Query: 567 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 622 E + + +P G++ +D T + D+SI +G +E A D Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385 Query: 623 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 669 + DS S + + AT + ++E K ++G+ V Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445 Query: 670 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 719 E P+T SQ +EL E E + L T T + LQ E+ + + Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505 Query: 720 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 779 A E ET DS + QE E ++S + K P+P+ + S Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557 Query: 780 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 838 + + D+ +P A + ++ K + L +A T P+ QD+ Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614 Query: 839 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 898 S P P+ + Q Q + +L +DS M L D E KP A A+ Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665 Query: 899 SFCESSSETPFHFTLPKEGDIIPPL 923 S + TLP++ + PPL Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686 Score = 40.8 bits (94), Expect = 0.013 Identities = 216/1053 (20%), Positives = 358/1053 (33%), Gaps = 207/1053 (19%) Query: 225 EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 280 E + E + + ++S+ + P T Q P V V P E D +++ AM Sbjct: 467 EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526 Query: 281 KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 338 Q E++ + + +K P P+ ++++ T+ D +EEGG L S Sbjct: 527 PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576 Query: 339 ---TPATTLHLLQLSGQRSLVQDSLST-----NSSDLV-APSPDAFRSTPFIVPSSPTEQ 389 A T+ Q +L QDS T +DL AP P A + S + Sbjct: 577 RKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV-----SQQAE 631 Query: 390 EGR---QDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI----- 441 EG QD M + P Q S P P+ + VS QA + Sbjct: 632 EGLTLPQDSVMTPPL-------PLQDTELSSAP-----KPVAAATLVSQQAEEGLTLPQD 679 Query: 442 SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEE-----QSNDGKKDGDMHSSSLTVECSK 496 S TP P + S P+ + S EE Q + + + L+ Sbjct: 680 SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 739 Query: 497 TSEIEPKNSPEDLGLSLTGDSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT 553 + + + GL+L DS L L ++ S +PK + ++ + E + Sbjct: 740 VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 799 Query: 554 EPMSPVL-------NSKFVPAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDIS 603 M+P L +S P +I+ A++G + L Q+ T DTD Sbjct: 800 SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPK 858 Query: 604 ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 663 +A ++ AE+ LT S P + LSS A EEG Sbjct: 859 PVAAATPVSQQ--AEE---GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEG 913 Query: 664 SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKE------------ 711 + +P+ + L++ S P L++ Q+ LQ E Sbjct: 914 LT------LPQDSAMTAPLPLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVAT 963 Query: 712 MPKKECSEAM-------EVETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSV 761 M ++E EA+ E ++ ++ P L + Q+ EA W DS++ Sbjct: 964 MAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023 Query: 762 VIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDL 821 + + P P E E + + P E C E R T + + Sbjct: 1024 GMEALSLPEPASGAGEEIAEALSR-----------PGREACLEARAHTGDGAKPD----- 1067 Query: 822 KSGTAETEPVEQDSSQPSLPLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQL 880 S ET VE PL + P L + P +++ ++ A++ Sbjct: 1068 -SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREE 1126 Query: 881 S--SDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEP 938 S + PSA A+++ +S E+ GA L P Sbjct: 1127 RGLSGKSTPEPTLPSAVATEASLDSCPESS---------------VGAVSSLDRGCPDAP 1171 Query: 939 KRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLV 997 S P S PE P+LG G + P V L L+ Sbjct: 1172 APTSAPT--SQQPE------------------PVLGLGSVEQPHEVPSV-----LGTPLL 1206 Query: 998 SPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSED 1057 P ++ +++P G + +A + P + + C+C+ QE+ E+ Sbjct: 1207 QPPENLAKGQPSTPVDRPL-GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEE 1263 Query: 1058 PPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQP---MKPISPVKDP---------- 1104 PP G+L P G + T P + P SP+ P Sbjct: 1264 PP-----GSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDL 1318 Query: 1105 ---VSPASQKMVIQGPSSPQGEAMVT--------DVLEDQKE---GRSTNKENPSKALIE 1150 + P Q GP SP G ++ D LE+ G + ++ ++ E Sbjct: 1319 ALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAE 1378 Query: 1151 RPSQNNIGIQTMECSLRVP-----ETVSAATQT 1178 Q+ + QT++C + P ET++ A Q+ Sbjct: 1379 LDEQDILAPQTVQCPAQAPAGGSEETIAKAKQS 1411 Score = 32.3 bits (72), Expect = 4.7 Identities = 124/651 (19%), Positives = 237/651 (36%), Gaps = 91/651 (13%) Query: 636 PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEE--LKEENMESVP 693 PA S++ Q EA+E+ PEE + + P +GEE ++S+ Sbjct: 307 PAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLS 366 Query: 694 LHLSLTETQSQGLCLQKE-----MPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQ 748 LS+TE + + + S A + + S + + +L ++ E+ Sbjct: 367 -DLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE 425 Query: 749 EAWEEA---TSEDSSV--VIVDVKEPSPRVDVSCEPLEGVEKCSD------SQSWEDIAP 797 E+ A ++D +V + + S R + E + + ++ +S + P Sbjct: 426 ESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTP 485 Query: 798 ---EIEPCAENRLDTK-EEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQ 853 ++ P + + T+ ++ E E D +G SQ + + + + + Sbjct: 486 HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAE- 544 Query: 854 ELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTL 913 + P QE+TS +L DS ++ D + + KP A A+ ++ + TL Sbjct: 545 --KLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR--KPVAAATIVPRQAKED----LTL 596 Query: 914 PKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPES--TIATSDVMSESMVETHDP 971 P++ + PPL P L PK + +S E T+ VM+ + Sbjct: 597 PQDSAMTPPL----PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPL------ 646 Query: 972 ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESV 1031 P D +L K V+ T S+++ + L P + Sbjct: 647 ------------PLQDTELSSAPKPVAAATLVSQQA-EEGLTLPQDSAMTPPLPLQDTDL 693 Query: 1032 ASPQKTMSVLSCICEARQENEARSED---PPTTPIRGNLLHF---PSSQGEEEKEKLEGD 1085 +S K ++ + + + +E +D P P++ L P + ++ E Sbjct: 694 SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEG 753 Query: 1086 HTIRQSQQPMKPISPVKD--------PVSPAS--QKMVIQGPSSPQGEAMVTDVLEDQKE 1135 T+ Q M P P++D PV+ A+ + +G + PQ AM + + Sbjct: 754 LTLPQ-DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812 Query: 1136 GRSTNKENPSKALIERPSQNN------------IGIQTMECSLRVPETVSAATQTIKNVC 1183 S K + ++ + ++ + +Q + S P+ V+AAT + Sbjct: 813 LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAE 871 Query: 1184 EQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQ 1234 E T D T+ S KPV+A + Q EE +PQ Sbjct: 872 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA----ATPVSQQAEEGLTLPQ 918 >gi|41281453 serine/threonine kinase 2 [Homo sapiens] Length = 1235 Score = 48.5 bits (114), Expect = 6e-05 Identities = 99/527 (18%), Positives = 198/527 (37%), Gaps = 128/527 (24%) Query: 452 SLPIPSQPQFSHDIFIPS-------------PSLEEQSNDGKKDGDMHSSSLTVECSKTS 498 SLPIP+ + S D+ I S S+ E++ + ++S L K + Sbjct: 330 SLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILN---EKPT 386 Query: 499 EIEPKNSPEDLGLSLTGDSCKLM---------LSTSEYSQSPKMESLSS---------HR 540 EP+ + ED+ +T + M + +E + PK+E+L + Sbjct: 387 TDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINS 446 Query: 541 IDEDGEN---------------TQIEDTEPMSPVLNSKFVPAE--NDSILMN-------- 575 + E EN ++ E + + +K + +E D+IL Sbjct: 447 VSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQET 506 Query: 576 -------PAQDGEVQLSQNDDKTK-GDDTDTRDDI----SILATGCKGRE--ETVAEDVC 621 A D EV L++ D + K G+D T+ D+ S + C+ + + V ED Sbjct: 507 GEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSA 566 Query: 622 IDLTCDSGSQAV--------------PSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGS 667 D + G + V + T+ + +++ E E K SS Sbjct: 567 EDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSS-E 625 Query: 668 EVEEIPETPCESQGEELKE-ENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETS 726 + +I E P ++GEE+ E + E + + + +T + L E +A +V T Sbjct: 626 NIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKAL-------GSEVQDASKVTT- 677 Query: 727 VISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS----PRVDVSCEPLEG 782 +++ +++E E V+ EP P ++++ + E Sbjct: 678 ---------------QIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGEN 722 Query: 783 VEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPS-LP 841 E+ E I P P +EN + + TA+T ++ + S S L Sbjct: 723 KEEIGSLSKTETILP---PESENPKENDNDSGT-------GSTADTSSIDLNLSISSFLS 772 Query: 842 LVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMA-NAKQLSSDAEAQ 887 + + L + +Q +T +KT + + +++ ++ +D++++ Sbjct: 773 KTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSK 819 Score = 39.7 bits (91), Expect = 0.030 Identities = 94/530 (17%), Positives = 197/530 (37%), Gaps = 61/530 (11%) Query: 46 SMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDT 105 S L +H P + P+ ++++ + EE DG E EN + P Sbjct: 284 SQLLQH-PFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSD 342 Query: 106 CGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQK--EKEKEEDTSGNTTHSL 163 S ++L Q + E + + ++ + L +K E E+ H Sbjct: 343 LSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHIT 402 Query: 164 GAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNS---GYTRLSDVDANTA 220 A+ A ++L + +++ + + D E ++V NS G + T Sbjct: 403 DAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETN 462 Query: 221 IKHEEQSNEDIPIAEQSS-KDIPVTAQPSKD-----VHVVKEQNPPPARSEDMPFSPKAS 274 I+H +S E+ +Q ++ + ++ KD V +V ++ +A+ Sbjct: 463 IEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETG----------EKEAN 512 Query: 275 VAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGC 334 + A++++ L+ ++ E K E + TQ+D+ ++ + + + +++ Sbjct: 513 IQAVDSEVGLTKEDTQE------KLGEDD--KTQKDVISNTSDVIGTCEAADVAQKVDED 564 Query: 335 SLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPF--IVPSSPTEQEGR 392 S T Q + + +V+ + +V P + P IV + E+ Sbjct: 565 SAEDT--------QSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKN 616 Query: 393 QDKPMDTS-----VLSEEGGEPFQKKLQSGEPVELE---------NPPLLPESTVSPQAS 438 +++ +++S + E G ++ +S E+E L E + + + Sbjct: 617 KEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVT 676 Query: 439 TPISQSTPVFPPG-----SLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVE 493 T I + P + + SQP + IPS ++ S + K+ ++ S S T Sbjct: 677 TQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKE--EIGSLSKTET 734 Query: 494 CSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDE 543 PK + D G T D+ + L+ S S K + S + E Sbjct: 735 ILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQE 784 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 47.8 bits (112), Expect = 1e-04 Identities = 97/450 (21%), Positives = 164/450 (36%), Gaps = 80/450 (17%) Query: 113 IEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQ 172 +++ P+ TSS + + +V+EE E+ E+E++ D + +T L D Sbjct: 964 VKRKEPPDTTSSGDQKRLRPSTSVDEED----EESERERDRDMA-DTPCELAKRDPK--- 1015 Query: 173 LGFGV-------LEL-SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 224 G GV LEL S ++ E+ ++ E + + + D D + Sbjct: 1016 -GVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES 1074 Query: 225 EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSE-----DMPFSPKASVAAME 279 E +ED ++E S KD + + V +V + + SE + S ++S ++ E Sbjct: 1075 ENDDEDTALSEASEKD-EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSE 1133 Query: 280 AKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAST 339 +E++ A+E E E E + +E + + DG E Sbjct: 1134 DEEEVVAREEEEE-------EEEEEMVAEESMASAGPEDFEQDG-------EEAALAPGA 1179 Query: 340 PATTLHLLQLSGQRSLVQDSLSTNSSDLVAPS--PDAFRSTPFIVPSSPTEQEGRQDKPM 397 PA SL + ++ VAP P P V E+ +P Sbjct: 1180 PAVD----------SLGMEEEVDIETEAVAPEERPSMLDEPPLPVG---VEEPADSREPP 1226 Query: 398 DTSVLSEEGG-----EPFQKKLQSGEPVELEN-----------PPLLPESTVSPQASTPI 441 + LS+EG EP K++++ P+ E PP++ + P P+ Sbjct: 1227 EEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP----PL 1282 Query: 442 SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIE 501 P PP P P SH P P E D H+ L +K+ E Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAE--------DHPPHTPGLCGSLAKSQSTE 1334 Query: 502 PKNSPEDLGLSLTGDSCKLMLSTSEYSQSP 531 + L+G S L LS+ + SP Sbjct: 1335 TVPATPGGEPPLSGGSSGLSLSSPQVPGSP 1364 Score = 44.3 bits (103), Expect = 0.001 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 12/181 (6%) Query: 656 KEHHPEEGSSGSEVEEIPETPCESQGEELKEE---NMESVPLHLSLTETQSQGLCLQKEM 712 ++ P+ SSG + P T + + EE + E +M P L+ + + G+ + Sbjct: 966 RKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPAR 1025 Query: 713 PKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPR 772 P + S E E +S + QE +E+EA EE ED D ++ S Sbjct: 1026 PLELDSGGEEDEKESLSEE---------QESTEEEEEAEEEEEEEDDDDDDSDDRDESEN 1076 Query: 773 VDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE 832 D E EK E+ + AE ++ +S E+E +S + +E E Sbjct: 1077 DDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEE 1136 Query: 833 Q 833 + Sbjct: 1137 E 1137 Score = 42.0 bits (97), Expect = 0.006 Identities = 106/516 (20%), Positives = 177/516 (34%), Gaps = 107/516 (20%) Query: 11 SQLDSDFSQQDTPCLIIEDS-------QPESQVLEDDSGSHFSMLSRHLPNLQTHKENPV 63 S+ + D DTPC + + + ++ LE DSG ++ +E Sbjct: 994 SERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEE 1053 Query: 64 LDVVSNPEQTAGEERGDGNSGFNEH----LKENKVADPVDSSNLDTCGSISQVIEQLPQP 119 + E ++ D + N+ L E D DS +T ++ E Sbjct: 1054 AEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSS 1113 Query: 120 NRT-SSVLGMSVESAPAVEEEKGEELEQKEKEKEED---TSGNTTHSLGAEDTASSQLGF 175 + SS S ES+P+ E++ E + ++E+E+EE+ + + S G ED Sbjct: 1114 ESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDF------- 1166 Query: 176 GVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAE 235 QD EE + + G D++ E S D P Sbjct: 1167 -------EQDGEEAALAPGA------PAVDSLGMEEEVDIETEAVAPEERPSMLDEP--- 1210 Query: 236 QSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ 295 +PV + D E+ P ++ M SP+ +EA+ LS + E L+ Sbjct: 1211 ----PLPVGVEEPADSREPPEE-PGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265 Query: 296 IQ------------------KSPEPEVLSTQEDLFDQSNKTVSSDG------------CS 325 ++ + P P + + D S+ +V + C Sbjct: 1266 VEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG 1325 Query: 326 TPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDA----------- 374 + ++ + ++ +TP L S SL + + APSP Sbjct: 1326 SLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGR 1385 Query: 375 -FRSTP-FIVPSS---------PTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELE 423 F TP F PS PT + + P+ + VL E G L P+ L Sbjct: 1386 DFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETG-------LPLPLPLPLP 1438 Query: 424 NPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQP 459 P LP + + QA P TP+ P P+ S P Sbjct: 1439 LPLALP-AVLRAQARAP----TPLPPLLPAPLASCP 1469 >gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] Length = 1522 Score = 47.0 bits (110), Expect = 2e-04 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%) Query: 355 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 410 L+ + LS+ + AP P P IV T Q + T++ +EGG +P Sbjct: 95 LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152 Query: 411 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 467 + G+ + + +PP P+S +P STP + + P P S+ + D + Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209 Query: 468 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 526 SP + DGD +SS + S + E + P GLS G + L + Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269 Query: 527 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 566 + P E SLS+ G+ D + ++ P++ + +P Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329 Query: 567 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 622 E + + +P G++ +D T + D+SI +G +E A D Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385 Query: 623 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 669 + DS S + + AT + ++E K ++G+ V Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445 Query: 670 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 719 E P+T SQ +EL E E + L T T + LQ E+ + + Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505 Query: 720 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 779 A E ET DS + QE E ++S + K P+P+ + S Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557 Query: 780 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 838 + + D+ +P A + ++ K + L +A T P+ QD+ Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614 Query: 839 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 898 S P P+ + Q Q + +L +DS M L D E KP A A+ Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665 Query: 899 SFCESSSETPFHFTLPKEGDIIPPL 923 S + TLP++ + PPL Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686 Score = 43.5 bits (101), Expect = 0.002 Identities = 121/642 (18%), Positives = 217/642 (33%), Gaps = 99/642 (15%) Query: 64 LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 123 ++V + AGEE D +G + + P + G S E+LP P + Sbjct: 496 VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553 Query: 124 SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 183 S L + +S ++EE G +L K + T A++ + + Sbjct: 554 S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608 Query: 184 QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 243 QD + ++ P V + S G T D + ++ P ++ + Sbjct: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668 Query: 244 TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 291 A+ + PP P + D+ +PK A++ + +A+E L+ + L Sbjct: 669 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 347 + +P+P +T + T+ D TP L+S P A T+ Sbjct: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788 Query: 348 QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 407 Q +L QDS T +P T+ +++S++ Sbjct: 789 QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831 Query: 408 EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFI 467 E S PPL + T A P++ +TPV Sbjct: 832 EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPV-------------------- 866 Query: 468 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEY 527 +Q+ +G + S + P + PE L ++ +E Sbjct: 867 -----SQQAEEGL---TLPQDSAMTAPLPLQDTGPTSGPEPLAVATP------QTLQAEA 912 Query: 528 SQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILMN---PAQDGEVQ 583 +P E +++ E GE E + L + PA D + + PA + Sbjct: 913 GCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTP 972 Query: 584 LSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDLTCDSGSQAVPSP 636 + +D D T + +S L G E +AE + C++ +G A P Sbjct: 973 WAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD- 1027 Query: 637 ATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 676 + + E L QE ++ +EH P G+ E+P+ P Sbjct: 1028 SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1067 Score = 40.0 bits (92), Expect = 0.023 Identities = 206/1034 (19%), Positives = 350/1034 (33%), Gaps = 209/1034 (20%) Query: 225 EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 280 E + E + + ++S+ + P T Q P V V P E D +++ AM Sbjct: 467 EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526 Query: 281 KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 338 Q E++ + + +K P P+ ++++ T+ D +EEGG L S Sbjct: 527 PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576 Query: 339 ---TPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDK 395 A T+ Q +L QDS T +P T+ Sbjct: 577 RKPVAAATIVPRQAKEDLTLPQDSAMTPP-----------------LPLQDTDLSSAPKP 619 Query: 396 PMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPI 455 +++S++ E S + PPL + T A P++ +T V + Sbjct: 620 VAAATIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGL 674 Query: 456 PSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 515 + PQ S +P L Q D D+ S+ V + + + GL+L Sbjct: 675 -TLPQDS----AMTPPLPLQ------DTDLSSAPKPVAAATLVSQQAEE-----GLTLPQ 718 Query: 516 DSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-------NSKFV 565 DS L L ++ S +PK + ++ + E + M+P L +S Sbjct: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778 Query: 566 PAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDISILATGCKGREETVAEDVCI 622 P +I+ A++G + L Q+ T DTD +A V++ Sbjct: 779 PVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT-----IVSQQAEE 832 Query: 623 DLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGE 682 LT S P + LSS A EEG + +P+ + Sbjct: 833 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLT------LPQDSAMTAPL 886 Query: 683 ELKEENMESVPLHLSLTETQSQGLCLQKE------------MPKKECSEAM-------EV 723 L++ S P L++ Q+ LQ E M ++E EA+ E Sbjct: 887 PLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEK 942 Query: 724 ETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSVVIVDVKEPSPRVDVSCEPL 780 ++ ++ P L + Q+ EA W DS++ + + P P E Sbjct: 943 NAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIA 1002 Query: 781 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 840 E + + P E C E R T + + S ET VE Sbjct: 1003 EALSR-----------PGREACLEARAHTGDGAKPD------SPQKETLEVENQQEGGLK 1045 Query: 841 PLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQLS--SDAEAQKLGKPSAHAS 897 PL + P L + P +++ ++ A++ S + PSA A+ Sbjct: 1046 PLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105 Query: 898 QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 957 ++ +S E+ GA L P S P S PE Sbjct: 1106 EASLDSCPESS---------------VGAVSSLDRGCPDAPAPTSAPT--SQQPE----- 1143 Query: 958 SDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPA 1016 P+LG G + P V L L+ P ++ +++P Sbjct: 1144 -------------PVLGLGSVEQPHEVPSV-----LGTPLLQPPENLAKGQPSTPVDRPL 1185 Query: 1017 TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGE 1076 G + +A + P + + C+C+ QE+ E+PP G+L P G Sbjct: 1186 -GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEEPP-----GSLGLPPPQAGV 1237 Query: 1077 EEKEKLEGDHTIRQSQQP---MKPISPVKDP-------------VSPASQKMVIQGPSSP 1120 + T P + P SP+ P + P Q GP SP Sbjct: 1238 QPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297 Query: 1121 QGEAMVT--------DVLEDQKE---GRSTNKENPSKALIERPSQNNIGIQTMECSLRVP 1169 G ++ D LE+ G + ++ ++ E Q+ + QT++C + P Sbjct: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1357 Query: 1170 -----ETVSAATQT 1178 ET++ A Q+ Sbjct: 1358 AGGSEETIAKAKQS 1371 >gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens] Length = 1522 Score = 47.0 bits (110), Expect = 2e-04 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%) Query: 355 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 410 L+ + LS+ + AP P P IV T Q + T++ +EGG +P Sbjct: 95 LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152 Query: 411 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 467 + G+ + + +PP P+S +P STP + + P P S+ + D + Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209 Query: 468 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 526 SP + DGD +SS + S + E + P GLS G + L + Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269 Query: 527 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 566 + P E SLS+ G+ D + ++ P++ + +P Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329 Query: 567 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 622 E + + +P G++ +D T + D+SI +G +E A D Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385 Query: 623 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 669 + DS S + + AT + ++E K ++G+ V Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445 Query: 670 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 719 E P+T SQ +EL E E + L T T + LQ E+ + + Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505 Query: 720 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 779 A E ET DS + QE E ++S + K P+P+ + S Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557 Query: 780 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 838 + + D+ +P A + ++ K + L +A T P+ QD+ Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614 Query: 839 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 898 S P P+ + Q Q + +L +DS M L D E KP A A+ Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665 Query: 899 SFCESSSETPFHFTLPKEGDIIPPL 923 S + TLP++ + PPL Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686 Score = 43.5 bits (101), Expect = 0.002 Identities = 121/642 (18%), Positives = 217/642 (33%), Gaps = 99/642 (15%) Query: 64 LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 123 ++V + AGEE D +G + + P + G S E+LP P + Sbjct: 496 VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553 Query: 124 SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 183 S L + +S ++EE G +L K + T A++ + + Sbjct: 554 S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608 Query: 184 QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 243 QD + ++ P V + S G T D + ++ P ++ + Sbjct: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668 Query: 244 TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 291 A+ + PP P + D+ +PK A++ + +A+E L+ + L Sbjct: 669 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728 Query: 292 SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 347 + +P+P +T + T+ D TP L+S P A T+ Sbjct: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788 Query: 348 QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 407 Q +L QDS T +P T+ +++S++ Sbjct: 789 QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831 Query: 408 EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFI 467 E S PPL + T A P++ +TPV Sbjct: 832 EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPV-------------------- 866 Query: 468 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEY 527 +Q+ +G + S + P + PE L ++ +E Sbjct: 867 -----SQQAEEGL---TLPQDSAMTAPLPLQDTGPTSGPEPLAVATP------QTLQAEA 912 Query: 528 SQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILMN---PAQDGEVQ 583 +P E +++ E GE E + L + PA D + + PA + Sbjct: 913 GCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTP 972 Query: 584 LSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDLTCDSGSQAVPSP 636 + +D D T + +S L G E +AE + C++ +G A P Sbjct: 973 WAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD- 1027 Query: 637 ATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 676 + + E L QE ++ +EH P G+ E+P+ P Sbjct: 1028 SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1067 Score = 40.0 bits (92), Expect = 0.023 Identities = 206/1034 (19%), Positives = 350/1034 (33%), Gaps = 209/1034 (20%) Query: 225 EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 280 E + E + + ++S+ + P T Q P V V P E D +++ AM Sbjct: 467 EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526 Query: 281 KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 338 Q E++ + + +K P P+ ++++ T+ D +EEGG L S Sbjct: 527 PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576 Query: 339 ---TPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDK 395 A T+ Q +L QDS T +P T+ Sbjct: 577 RKPVAAATIVPRQAKEDLTLPQDSAMTPP-----------------LPLQDTDLSSAPKP 619 Query: 396 PMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPI 455 +++S++ E S + PPL + T A P++ +T V + Sbjct: 620 VAAATIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGL 674 Query: 456 PSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 515 + PQ S +P L Q D D+ S+ V + + + GL+L Sbjct: 675 -TLPQDS----AMTPPLPLQ------DTDLSSAPKPVAAATLVSQQAEE-----GLTLPQ 718 Query: 516 DSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-------NSKFV 565 DS L L ++ S +PK + ++ + E + M+P L +S Sbjct: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778 Query: 566 PAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDISILATGCKGREETVAEDVCI 622 P +I+ A++G + L Q+ T DTD +A V++ Sbjct: 779 PVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT-----IVSQQAEE 832 Query: 623 DLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGE 682 LT S P + LSS A EEG + +P+ + Sbjct: 833 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLT------LPQDSAMTAPL 886 Query: 683 ELKEENMESVPLHLSLTETQSQGLCLQKE------------MPKKECSEAM-------EV 723 L++ S P L++ Q+ LQ E M ++E EA+ E Sbjct: 887 PLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEK 942 Query: 724 ETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSVVIVDVKEPSPRVDVSCEPL 780 ++ ++ P L + Q+ EA W DS++ + + P P E Sbjct: 943 NAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIA 1002 Query: 781 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 840 E + + P E C E R T + + S ET VE Sbjct: 1003 EALSR-----------PGREACLEARAHTGDGAKPD------SPQKETLEVENQQEGGLK 1045 Query: 841 PLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQLS--SDAEAQKLGKPSAHAS 897 PL + P L + P +++ ++ A++ S + PSA A+ Sbjct: 1046 PLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105 Query: 898 QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 957 ++ +S E+ GA L P S P S PE Sbjct: 1106 EASLDSCPESS---------------VGAVSSLDRGCPDAPAPTSAPT--SQQPE----- 1143 Query: 958 SDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPA 1016 P+LG G + P V L L+ P ++ +++P Sbjct: 1144 -------------PVLGLGSVEQPHEVPSV-----LGTPLLQPPENLAKGQPSTPVDRPL 1185 Query: 1017 TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGE 1076 G + +A + P + + C+C+ QE+ E+PP G+L P G Sbjct: 1186 -GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEEPP-----GSLGLPPPQAGV 1237 Query: 1077 EEKEKLEGDHTIRQSQQP---MKPISPVKDP-------------VSPASQKMVIQGPSSP 1120 + T P + P SP+ P + P Q GP SP Sbjct: 1238 QPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297 Query: 1121 QGEAMVT--------DVLEDQKE---GRSTNKENPSKALIERPSQNNIGIQTMECSLRVP 1169 G ++ D LE+ G + ++ ++ E Q+ + QT++C + P Sbjct: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1357 Query: 1170 -----ETVSAATQT 1178 ET++ A Q+ Sbjct: 1358 AGGSEETIAKAKQS 1371 >gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 47.0 bits (110), Expect = 2e-04 Identities = 94/388 (24%), Positives = 140/388 (36%), Gaps = 71/388 (18%) Query: 368 VAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPL 427 VAP+P P I P ++E + + D + +GG+ +++ SG P Sbjct: 158 VAPAPVLMNQPPQIAP----KRERKTIRIRDPN----QGGKDITEEIMSGARTASTPTPP 209 Query: 428 LPESTVSPQAS--TP---------------ISQSTPVFP-PGSLPIPSQPQFSHDIFIPS 469 + PQA+ TP I P P P P SQP PS Sbjct: 210 QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269 Query: 470 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---------KNSPEDLGLSLTGDSCKL 520 P LE S + ++T E P + SPE L+ ++ Sbjct: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329 Query: 521 MLST----SEYSQSPKMES--LSSHRIDEDGENTQI--EDTEP---MSPVLNSKFVPAEN 569 LS SE+S SP L+SH ++ N + ED EP SP L Sbjct: 330 TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSE 389 Query: 570 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 629 + + P +Q ++ G + D+S ++ E+ ++T Sbjct: 390 SPVPIAPT-------AQPEELLNGAPSPPAVDLSPVSE---------PEEQAKEVTASMA 433 Query: 630 SQAVPS--PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE 687 +PS PAT A S QEE ME +E EEG +G E E E GEEL Sbjct: 434 PPTIPSATPATAPSATSPA--QEEEME-EEEEEEEGEAG----EAGEAESEKGGEELLPP 486 Query: 688 NMESVPLHLSLTETQSQGLCLQKEMPKK 715 +P +LS + + +PK+ Sbjct: 487 ESTPIPANLSQNLEAAAATQVAVSVPKR 514 >gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 isoform 2 [Homo sapiens] Length = 1512 Score = 47.0 bits (110), Expect = 2e-04 Identities = 94/388 (24%), Positives = 140/388 (36%), Gaps = 71/388 (18%) Query: 368 VAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPL 427 VAP+P P I P ++E + + D + +GG+ +++ SG P Sbjct: 71 VAPAPVLMNQPPQIAP----KRERKTIRIRDPN----QGGKDITEEIMSGARTASTPTPP 122 Query: 428 LPESTVSPQAS--TP---------------ISQSTPVFP-PGSLPIPSQPQFSHDIFIPS 469 + PQA+ TP I P P P P SQP PS Sbjct: 123 QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 182 Query: 470 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---------KNSPEDLGLSLTGDSCKL 520 P LE S + ++T E P + SPE L+ ++ Sbjct: 183 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 242 Query: 521 MLST----SEYSQSPKMES--LSSHRIDEDGENTQI--EDTEP---MSPVLNSKFVPAEN 569 LS SE+S SP L+SH ++ N + ED EP SP L Sbjct: 243 TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSE 302 Query: 570 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 629 + + P +Q ++ G + D+S ++ E+ ++T Sbjct: 303 SPVPIAPT-------AQPEELLNGAPSPPAVDLSPVSE---------PEEQAKEVTASMA 346 Query: 630 SQAVPS--PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE 687 +PS PAT A S QEE ME +E EEG +G E E E GEEL Sbjct: 347 PPTIPSATPATAPSATSPA--QEEEME-EEEEEEEGEAG----EAGEAESEKGGEELLPP 399 Query: 688 NMESVPLHLSLTETQSQGLCLQKEMPKK 715 +P +LS + + +PK+ Sbjct: 400 ESTPIPANLSQNLEAAAATQVAVSVPKR 427 >gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 47.0 bits (110), Expect = 2e-04 Identities = 94/388 (24%), Positives = 140/388 (36%), Gaps = 71/388 (18%) Query: 368 VAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPL 427 VAP+P P I P ++E + + D + +GG+ +++ SG P Sbjct: 158 VAPAPVLMNQPPQIAP----KRERKTIRIRDPN----QGGKDITEEIMSGARTASTPTPP 209 Query: 428 LPESTVSPQAS--TP---------------ISQSTPVFP-PGSLPIPSQPQFSHDIFIPS 469 + PQA+ TP I P P P P SQP PS Sbjct: 210 QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269 Query: 470 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---------KNSPEDLGLSLTGDSCKL 520 P LE S + ++T E P + SPE L+ ++ Sbjct: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329 Query: 521 MLST----SEYSQSPKMES--LSSHRIDEDGENTQI--EDTEP---MSPVLNSKFVPAEN 569 LS SE+S SP L+SH ++ N + ED EP SP L Sbjct: 330 TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSE 389 Query: 570 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 629 + + P +Q ++ G + D+S ++ E+ ++T Sbjct: 390 SPVPIAPT-------AQPEELLNGAPSPPAVDLSPVSE---------PEEQAKEVTASMA 433 Query: 630 SQAVPS--PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE 687 +PS PAT A S QEE ME +E EEG +G E E E GEEL Sbjct: 434 PPTIPSATPATAPSATSPA--QEEEME-EEEEEEEGEAG----EAGEAESEKGGEELLPP 486 Query: 688 NMESVPLHLSLTETQSQGLCLQKEMPKK 715 +P +LS + + +PK+ Sbjct: 487 ESTPIPANLSQNLEAAAATQVAVSVPKR 514 >gi|11968023 zinc finger protein 106 homolog [Homo sapiens] Length = 1883 Score = 47.0 bits (110), Expect = 2e-04 Identities = 94/468 (20%), Positives = 177/468 (37%), Gaps = 91/468 (19%) Query: 392 RQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQS--TPVFP 449 +Q M+ S L + Q ++ EP E +P +P S + ++ S + P Sbjct: 1095 KQQITMEMSALRTHRIQILQGLQETYEPSE--HPDQVPCSLTRERRNSRSQTSIDAALLP 1152 Query: 450 PGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDL 509 P+ +P SH PSP+ H S + S + EP + +D Sbjct: 1153 TPFFPLFLEPPSSH--VSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIKQEPMSPEQDE 1210 Query: 510 GLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAEN 569 ++ S +S E L ++R +I D+ P+ PV+ ++ E+ Sbjct: 1211 NVNAVPPSSACNVSK---------ELLEANR--------EISDSCPVYPVITARLSLPES 1253 Query: 570 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 629 P+Q+ + + Q + + + +++ + + + +G E T +SG Sbjct: 1254 TESFHEPSQELKFSVEQRNTRNR-ENSPSSQSAGLSSINKEGEEPTKG---------NSG 1303 Query: 630 SQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENM 689 S+A S R S E +E + H P + PE ES Sbjct: 1304 SEACTSSFLRLSFAS-----ETPLEKEPHSPADQ---------PEQQAES---------- 1339 Query: 690 ESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEV------ETSVISIDSPQKL------- 736 +LT +++G +K++ KK+ A V E V+++ +K+ Sbjct: 1340 -------TLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVKPVRKVKAGKLIK 1392 Query: 737 ------AILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQ 790 + + +EQE+ + DSS+ ++++ P V V+ + E E+ DS Sbjct: 1393 GGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEV-VAIDSSESGEEKPDSP 1451 Query: 791 SWEDI--APEIEPCAENR-----LDTKEEKSVEYEGDLKSGTAETEPV 831 S +DI + E P +R + + E Y+ + AET+ V Sbjct: 1452 SKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTV 1499 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.126 0.354 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,053,199 Number of Sequences: 37866 Number of extensions: 4704591 Number of successful extensions: 23512 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 683 Number of HSP's that attempted gapping in prelim test: 19531 Number of HSP's gapped (non-prelim): 4295 length of query: 1977 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1860 effective length of database: 13,817,196 effective search space: 25699984560 effective search space used: 25699984560 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.