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Search of human proteins with 213972589
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|213972589 TPTE and PTEN homologous inositol lipid
phosphatase isoform alpha [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 907 0.0
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 867 0.0
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 785 0.0
gi|109689707 transmembrane phosphatase with tensin homology isof... 741 0.0
gi|40549433 transmembrane phosphatase with tensin homology isofo... 719 0.0
gi|40549435 transmembrane phosphatase with tensin homology isofo... 714 0.0
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 221 8e-58
gi|157384971 cyclin G associated kinase [Homo sapiens] 122 7e-28
gi|65288071 tensin 3 [Homo sapiens] 119 7e-27
gi|66529407 tensin [Homo sapiens] 114 1e-25
gi|239756009 PREDICTED: similar to transmembrane phosphoinositid... 109 6e-24
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 103 4e-22
gi|38787970 tensin like C1 domain containing phosphatase isoform... 100 5e-21
gi|38787957 tensin like C1 domain containing phosphatase isoform... 100 5e-21
gi|38787941 tensin like C1 domain containing phosphatase isoform... 100 5e-21
gi|91992155 hydrogen voltage-gated channel 1 [Homo sapiens] 42 0.001
gi|91992153 hydrogen voltage-gated channel 1 [Homo sapiens] 42 0.001
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens] 41 0.002
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens] 41 0.002
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens] 41 0.002
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 40 0.006
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 40 0.006
gi|205277447 dual specificity phosphatase 11 [Homo sapiens] 39 0.012
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 36 0.062
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 36 0.062
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens] 36 0.081
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens] 36 0.081
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens] 36 0.081
gi|30089952 protein tyrosine phosphatase domain containing 1 pro... 36 0.081
gi|30089950 protein tyrosine phosphatase domain containing 1 pro... 36 0.081
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 907 bits (2345), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF 60
MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF
Sbjct: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF 60
Query: 61 TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL 120
TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL
Sbjct: 61 TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL 120
Query: 121 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH 180
EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
Sbjct: 121 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH 180
Query: 181 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA 240
RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
Sbjct: 181 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA 240
Query: 241 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG 300
IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
Sbjct: 241 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG 300
Query: 301 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH 360
YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
Sbjct: 301 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH 360
Query: 361 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL 420
DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
Sbjct: 361 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL 420
Query: 421 DNPHKQKAWKIYPPEFAVEILFGEK 445
DNPHKQKAWKIYPPEFAVEILFGEK
Sbjct: 421 DNPHKQKAWKIYPPEFAVEILFGEK 445
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 867 bits (2240), Expect = 0.0
Identities = 444/522 (85%), Positives = 444/522 (85%), Gaps = 77/522 (14%)
Query: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKR-------------------- 40
MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISK
Sbjct: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYD 60
Query: 41 -----------------IFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFL 83
IFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFL
Sbjct: 61 SKIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFL 120
Query: 84 MDVLLRVFVEG----------------------------------------WTHLVRLLR 103
MDVLLRVFVEG WTHLVRLLR
Sbjct: 121 MDVLLRVFVEGRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIPRWTHLVRLLR 180
Query: 104 LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS 163
LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
Sbjct: 181 LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS 240
Query: 164 FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF 223
FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF
Sbjct: 241 FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF 300
Query: 224 TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH 283
TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH
Sbjct: 301 TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH 360
Query: 284 SNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVME 343
SNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVME
Sbjct: 361 SNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVME 420
Query: 344 KKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWF 403
KKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWF
Sbjct: 421 KKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWF 480
Query: 404 NTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 445
NTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
Sbjct: 481 NTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 522
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 785 bits (2026), Expect = 0.0
Identities = 393/445 (88%), Positives = 397/445 (89%), Gaps = 34/445 (7%)
Query: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF 60
MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISK + L+
Sbjct: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLE----------RLSKFEV 50
Query: 61 TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL 120
D++ E WTHLVRLLRLIILIRIFHLLHQKRQL
Sbjct: 51 EDAENVASYE------------------------WTHLVRLLRLIILIRIFHLLHQKRQL 86
Query: 121 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH 180
EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
Sbjct: 87 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH 146
Query: 181 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA 240
RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
Sbjct: 147 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA 206
Query: 241 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG 300
IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
Sbjct: 207 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG 266
Query: 301 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH 360
YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
Sbjct: 267 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH 326
Query: 361 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL 420
DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
Sbjct: 327 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL 386
Query: 421 DNPHKQKAWKIYPPEFAVEILFGEK 445
DNPHKQKAWKIYPPEFAVEILFGEK
Sbjct: 387 DNPHKQKAWKIYPPEFAVEILFGEK 411
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 741 bits (1912), Expect = 0.0
Identities = 384/521 (73%), Positives = 409/521 (78%), Gaps = 77/521 (14%)
Query: 2 NESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRI-------------------- 41
N+SPQT+EFKG TEEAPAKESPHTSEFKGAA VSPIS+ +
Sbjct: 20 NDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVLARLSKFEVEDAENVASYDS 79
Query: 42 -----------------FGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFLM 84
FGVFLVLLDVTL+LADLIFTDSKLYIPLEYRSISLAI LFFLM
Sbjct: 80 KIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLM 139
Query: 85 DVLLRVFVE----------------------------------------GWTHLVRLLRL 104
DVLLRVFVE WTHL+RLLRL
Sbjct: 140 DVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRL 199
Query: 105 IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF 164
IIL+RIFHL HQKRQLEKL+RR VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF
Sbjct: 200 IILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSF 259
Query: 165 YRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFT 224
YRNPI+EVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRV RIMIDDHNVPTLH+MVVFT
Sbjct: 260 YRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFT 319
Query: 225 KEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHS 284
KEVNEWMAQDLENIVAIHCKGG RTGTMVCA LIASEI TA+ESLYYFGERRT+KTHS
Sbjct: 320 KEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHS 379
Query: 285 NKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEK 344
KFQGVETPSQ RYV YFAQVKHLYNWNLPPRRILFIK FIIYSI V DLK+Q+ MEK
Sbjct: 380 EKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEK 439
Query: 345 KVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFN 404
KVVFS+ SLG CS+L +I TDKILI+V+DG PLYDDVKVQFF SNLP YYDNC F+FW +
Sbjct: 440 KVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLH 499
Query: 405 TSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK 445
TSFI+NNRL LP+NELDN HKQKA +IYP +FAVEILFGEK
Sbjct: 500 TSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK 540
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 719 bits (1856), Expect = 0.0
Identities = 373/503 (74%), Positives = 402/503 (79%), Gaps = 59/503 (11%)
Query: 2 NESPQTNEFKGTTEEAPAKES-----------------PHTSEFKGA--ALVSPISKRIF 42
N+SPQT+EFKG TEEAPAKES + S+ K ++VS + +F
Sbjct: 20 NDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLF 79
Query: 43 GVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVE--------- 93
GVFLVLLDVTL+LADLIFTDSKLYIPLEYRSISLAI LFFLMDVLLRVFVE
Sbjct: 80 GVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDL 139
Query: 94 -------------------------------GWTHLVRLLRLIILIRIFHLLHQKRQLEK 122
WTHL+RLLRLIIL+RIFHL HQKRQLEK
Sbjct: 140 FNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEK 199
Query: 123 LMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRN 182
L+RR VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPI+EVVRFLDKKHRN
Sbjct: 200 LIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRN 259
Query: 183 HYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIH 242
HYRVYNLCSERAYDPKHFHNRV RIMIDDHNVPTLH+MVVFTKEVNEWMAQDLENIVAIH
Sbjct: 260 HYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIH 319
Query: 243 CKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYF 302
CKGG RTGTMVCA LIASEI TA+ESLYYFGERRT+KTHS KFQGVETPSQ RYV YF
Sbjct: 320 CKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYF 379
Query: 303 AQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDI 362
AQVKHLYNWNLPPRRILFIK FIIYSI V DLK+Q+ MEKKVVFS+ SLG CS+L +I
Sbjct: 380 AQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNI 439
Query: 363 ETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDN 422
TDKILI+V+DG PLYDDVKVQFF SNLP YYDNC F+FW +TSFI+NNRL LP+NELDN
Sbjct: 440 TTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDN 499
Query: 423 PHKQKAWKIYPPEFAVEILFGEK 445
HKQKA +IYP +FAVEILFGEK
Sbjct: 500 LHKQKARRIYPSDFAVEILFGEK 522
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 714 bits (1844), Expect = 0.0
Identities = 369/502 (73%), Positives = 396/502 (78%), Gaps = 57/502 (11%)
Query: 1 MNESPQTNEFKGTTEEAPAKESPHTSEFKGA-----------------ALVSPISKRIFG 43
MNESP + G E +SP TSEFKGA ++VS + +FG
Sbjct: 1 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESSKIKKIVHSIVSSFAFGLFG 60
Query: 44 VFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVE---------- 93
VFLVLLDVTL+LADLIFTDSKLYIPLEYRSISLAI LFFLMDVLLRVFVE
Sbjct: 61 VFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLF 120
Query: 94 ------------------------------GWTHLVRLLRLIILIRIFHLLHQKRQLEKL 123
WTHL+RLLRLIIL+RIFHL HQKRQLEKL
Sbjct: 121 NILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKL 180
Query: 124 MRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNH 183
+RR VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPI+EVVRFLDKKHRNH
Sbjct: 181 IRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNH 240
Query: 184 YRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHC 243
YRVYNLCSERAYDPKHFHNRV RIMIDDHNVPTLH+MVVFTKEVNEWMAQDLENIVAIHC
Sbjct: 241 YRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHC 300
Query: 244 KGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA 303
KGG RTGTMVCA LIASEI TA+ESLYYFGERRT+KTHS KFQGVETPSQ RYV YFA
Sbjct: 301 KGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA 360
Query: 304 QVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE 363
QVKHLYNWNLPPRRILFIK FIIYSI V DLK+Q+ MEKKVVFS+ SLG CS+L +I
Sbjct: 361 QVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT 420
Query: 364 TDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNP 423
TDKILI+V+DG PLYDDVKVQFF SNLP YYDNC F+FW +TSFI+NNRL LP+NELDN
Sbjct: 421 TDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNL 480
Query: 424 HKQKAWKIYPPEFAVEILFGEK 445
HKQKA +IYP +FAVEILFGEK
Sbjct: 481 HKQKARRIYPSDFAVEILFGEK 502
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 221 bits (564), Expect = 8e-58
Identities = 133/358 (37%), Positives = 191/358 (53%), Gaps = 52/358 (14%)
Query: 123 LMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRN 182
+++ +VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I++VVRFLD KH+N
Sbjct: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
Query: 183 HYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIH 242
HY++YNLC+ER YD F+ RV++ +DHN P L + F +++++W+++D ++ AIH
Sbjct: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
Query: 243 CKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYF 302
CK GKGRTG M+CA L+ FL A+E+L ++GE RT +GV PSQ RYV Y+
Sbjct: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYY 178
Query: 303 AQV--KHLYNWNLPPRRILFIKRFI--IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSI 358
+ + HL + P +LF K I G C+ + V K ++SS S
Sbjct: 179 SYLLKNHL---DYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPT--- 232
Query: 359 LHDIETDKILINVYDGP-PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFI--------- 408
DK + + P P+ D+KV+FF + F FW NT FI
Sbjct: 233 ---RREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
Query: 409 -QNNRLC-----------------------LPRNELDNPHKQKAWKIYPPEFAVEILF 442
+N LC L +N+LD +K KA + + P F V++ F
Sbjct: 290 VENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 122 bits (306), Expect = 7e-28
Identities = 64/165 (38%), Positives = 89/165 (53%), Gaps = 9/165 (5%)
Query: 141 DLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHF 200
DLD++Y+T RI MSFP+ G +S +N IE+V FLD KH HY VYNL S R Y P F
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNL-SPRTYRPSRF 465
Query: 201 HNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIA 260
HNRVS P LH + + ++ W+ QD +N+ +HC G+ + VC+ L
Sbjct: 466 HNRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCF 525
Query: 261 SEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 305
+F TAE ++Y F +R G+ PS RY+ Y +
Sbjct: 526 CRLFSTAEAAVYMFSMKRCP-------PGI-WPSHKRYIEYMCDM 562
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 119 bits (297), Expect = 7e-27
Identities = 86/310 (27%), Positives = 149/310 (48%), Gaps = 19/310 (6%)
Query: 138 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDP 197
+G LDLTY+TERIIA+SFP+ + Y + ++EV R L KH ++Y V NL SE+ YD
Sbjct: 3 EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
Query: 198 KHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCAL 257
+ ++ + + + P L +M K W+ +L+++V IHC+GGKGR G ++ +
Sbjct: 62 TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
Query: 258 LIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPR 316
+ + + +A+++L F + K + +K + PSQ RYV + + + N P
Sbjct: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
Query: 317 RILFIKRFIIYSI----RGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVY 372
LF+ I++ G VC +++ + V++S + +I I +
Sbjct: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYN----VGPENPSRICIVIE 231
Query: 373 DGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIY 432
L DV V+ + + F F+T +Q L + +LDN K +
Sbjct: 232 PAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR---F 288
Query: 433 PPEFAVEILF 442
P VE++F
Sbjct: 289 PDYGKVELVF 298
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 114 bits (286), Expect = 1e-25
Identities = 90/314 (28%), Positives = 150/314 (47%), Gaps = 19/314 (6%)
Query: 134 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSER 193
R D +LDL YVTERIIA+SFPS+ + +R+ + EV + L KH +Y ++NL SER
Sbjct: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
Query: 194 AYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTM 253
D H +V D + P L ++ K ++ W+ D N+V +H KG +GR G +
Sbjct: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
Query: 254 VCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWN 312
+ A + S I +A+++L F +R + +K + PSQ RYV YF+ + N
Sbjct: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
Query: 313 LPPRRILFIKRFIIYSIRG----DVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKIL 368
P LF+ I++ I C +++ + V++S G +I D +T +
Sbjct: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTS---GIYNIPGDSQT-SVC 233
Query: 369 INVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKA 428
I + G L D+ ++ + + F F+T I + + + +LD+ K
Sbjct: 234 ITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR 293
Query: 429 WKIYPPEFAVEILF 442
+P VE +F
Sbjct: 294 ---FPEYGKVEFVF 304
>gi|239756009 PREDICTED: similar to transmembrane phosphoinositide
3-phosphatase and tensin homolog 2, partial [Homo
sapiens]
Length = 99
Score = 109 bits (272), Expect = 6e-24
Identities = 50/56 (89%), Positives = 51/56 (91%)
Query: 192 ERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 247
ERAYDPKHFHNRVSRIMIDDHNVPTL EMV F+KEV EWMAQD ENIV IHCKGGK
Sbjct: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
Length = 913
Score = 103 bits (256), Expect = 4e-22
Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 11/178 (6%)
Query: 128 VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVY 187
V ++ YT+ DLD TYVT RII MSFP +RN ++++ FLD +H +HY VY
Sbjct: 52 VIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVY 109
Query: 188 NLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 247
NL S ++Y FH+RVS P+LH + + + W+ Q+ +N+ +HC G+
Sbjct: 110 NL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGR 168
Query: 248 GRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 305
+ +V A+ I ++ T ++ +R S PS RY+GY +
Sbjct: 169 AASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLS--------PSHRRYLGYMCDL 218
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 99.8 bits (247), Expect = 5e-21
Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)
Query: 140 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 199
+DLDLTYVTERI+A +FP+ + +R + E+ L KHR+ Y ++NL SE+ +D
Sbjct: 5 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 63
Query: 200 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 259
+ +V + + P L ++ K + W++ D +++V ++CKG KG+ G +V A +
Sbjct: 64 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 123
Query: 260 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 318
S+I A+++L R K +K PSQ RY+ YF+ + N P
Sbjct: 124 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 177
Query: 319 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 375
LF+ +I + Q ++ ++ S L S ++ I ++ I++
Sbjct: 178 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 234
Query: 376 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 433
L DV V + F F+T I +L P+++LD +AW + +P
Sbjct: 235 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 289
Query: 434 PEFAVEILF 442
+ +VE +F
Sbjct: 290 FQASVEFVF 298
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 99.8 bits (247), Expect = 5e-21
Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)
Query: 140 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 199
+DLDLTYVTERI+A +FP+ + +R + E+ L KHR+ Y ++NL SE+ +D
Sbjct: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
Query: 200 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 259
+ +V + + P L ++ K + W++ D +++V ++CKG KG+ G +V A +
Sbjct: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
Query: 260 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 318
S+I A+++L R K +K PSQ RY+ YF+ + N P
Sbjct: 248 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 301
Query: 319 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 375
LF+ +I + Q ++ ++ S L S ++ I ++ I++
Sbjct: 302 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 358
Query: 376 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 433
L DV V + F F+T I +L P+++LD +AW + +P
Sbjct: 359 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 413
Query: 434 PEFAVEILF 442
+ +VE +F
Sbjct: 414 FQASVEFVF 422
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 99.8 bits (247), Expect = 5e-21
Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)
Query: 140 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 199
+DLDLTYVTERI+A +FP+ + +R + E+ L KHR+ Y ++NL SE+ +D
Sbjct: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
Query: 200 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 259
+ +V + + P L ++ K + W++ D +++V ++CKG KG+ G +V A +
Sbjct: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
Query: 260 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 318
S+I A+++L R K +K PSQ RY+ YF+ + N P
Sbjct: 258 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 311
Query: 319 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 375
LF+ +I + Q ++ ++ S L S ++ I ++ I++
Sbjct: 312 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 368
Query: 376 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 433
L DV V + F F+T I +L P+++LD +AW + +P
Sbjct: 369 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 423
Query: 434 PEFAVEILF 442
+ +VE +F
Sbjct: 424 FQASVEFVF 432
>gi|91992155 hydrogen voltage-gated channel 1 [Homo sapiens]
Length = 273
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 17/121 (14%)
Query: 18 PAKESPHTSEFKGAA--LVSPISKRIFGVFLVLLDVTLLLADLIFT------DSKLYIPL 69
PA +P +F+G L S ++ + LV+LD L+LA+LI D Y +
Sbjct: 80 PAPRAP--LDFRGMLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAM 137
Query: 70 EYRSISLAIGLFFLMDVLLRVFV---EGWTHLVRLLRLIILIRIF----HLLHQKRQLEK 122
+ +S+ I +FF+M+++ ++FV E + H +L ++++ F LL Q+ Q E
Sbjct: 138 VFHYMSITILVFFMMEIIFKLFVFRLEFFHHKFEILDAVVVVVSFILDIVLLFQEHQFEA 197
Query: 123 L 123
L
Sbjct: 198 L 198
>gi|91992153 hydrogen voltage-gated channel 1 [Homo sapiens]
Length = 273
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 17/121 (14%)
Query: 18 PAKESPHTSEFKGAA--LVSPISKRIFGVFLVLLDVTLLLADLIFT------DSKLYIPL 69
PA +P +F+G L S ++ + LV+LD L+LA+LI D Y +
Sbjct: 80 PAPRAP--LDFRGMLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAM 137
Query: 70 EYRSISLAIGLFFLMDVLLRVFV---EGWTHLVRLLRLIILIRIF----HLLHQKRQLEK 122
+ +S+ I +FF+M+++ ++FV E + H +L ++++ F LL Q+ Q E
Sbjct: 138 VFHYMSITILVFFMMEIIFKLFVFRLEFFHHKFEILDAVVVVVSFILDIVLLFQEHQFEA 197
Query: 123 L 123
L
Sbjct: 198 L 198
>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
Length = 461
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)
Query: 105 IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVT-ERIIAMSFPSSGRQ- 162
I L+ FH + + Q L + ++ + + DL ++ +R IA P S +
Sbjct: 140 ITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARL 199
Query: 163 --SFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEM 220
++++ E +++ K+ N + L ++R YD K F + D H++
Sbjct: 200 ESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAKRFTDAG----FDHHDLFFADGS 252
Query: 221 VVFTKEVNEWM--AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESL 271
V E++ ++ E +A+HCK G GRTGT++ A I +TA E++
Sbjct: 253 TPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLI-ACYIMKHYRMTAAETI 304
>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
Length = 459
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)
Query: 105 IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVT-ERIIAMSFPSSGRQ- 162
I L+ FH + + Q L + ++ + + DL ++ +R IA P S +
Sbjct: 177 ITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARL 236
Query: 163 --SFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEM 220
++++ E +++ K+ N + L ++R YD K F + D H++
Sbjct: 237 ESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAKRFTDAG----FDHHDLFFADGS 289
Query: 221 VVFTKEVNEWM--AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESL 271
V E++ ++ E +A+HCK G GRTGT++ A I +TA E++
Sbjct: 290 TPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLI-ACYIMKHYRMTAAETI 341
>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
Length = 498
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)
Query: 105 IILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVT-ERIIAMSFPSSGRQ- 162
I L+ FH + + Q L + ++ + + DL ++ +R IA P S +
Sbjct: 177 ITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARL 236
Query: 163 --SFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEM 220
++++ E +++ K+ N + L ++R YD K F + D H++
Sbjct: 237 ESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAKRFTDAG----FDHHDLFFADGS 289
Query: 221 VVFTKEVNEWM--AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESL 271
V E++ ++ E +A+HCK G GRTGT++ A I +TA E++
Sbjct: 290 TPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLI-ACYIMKHYRMTAAETI 341
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 39.7 bits (91), Expect = 0.006
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 185 RVYNLCSERAYDP----KHFHNRVSRIMIDDHNVP-TLHEMVVFTKEVNEWMAQDL-ENI 238
R + +C E D +HFH V DH VP T ++ F + V +++ +
Sbjct: 2062 REFKICGEEQLDAHRLIRHFHYTVW----PDHGVPETTQSLIQFVRTVRDYINRSPGAGP 2117
Query: 239 VAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRY 298
+HC G GRTGT + I + L +++S+ +G + H + V+T Q Y
Sbjct: 2118 TVVHCSAGVGRTGTFIALDRILQQ--LDSKDSVDIYGAVHDLRLH--RVHMVQTECQYVY 2173
Query: 299 V 299
+
Sbjct: 2174 L 2174
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 39.7 bits (91), Expect = 0.006
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 185 RVYNLCSERAYDP----KHFHNRVSRIMIDDHNVP-TLHEMVVFTKEVNEWMAQDL-ENI 238
R + +C E D +HFH V DH VP T ++ F + V +++ +
Sbjct: 1844 REFKICGEEQLDAHRLIRHFHYTVW----PDHGVPETTQSLIQFVRTVRDYINRSPGAGP 1899
Query: 239 VAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRY 298
+HC G GRTGT + I + L +++S+ +G + H + V+T Q Y
Sbjct: 1900 TVVHCSAGVGRTGTFIALDRILQQ--LDSKDSVDIYGAVHDLRLH--RVHMVQTECQYVY 1955
Query: 299 V 299
+
Sbjct: 1956 L 1956
>gi|205277447 dual specificity phosphatase 11 [Homo sapiens]
Length = 377
Score = 38.5 bits (88), Expect = 0.012
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 191 SERAYDPKHFHNRVS--RIMIDDHNVPTLHEMVVFTKEVNEWMAQDLEN--IVAIHCKGG 246
++R Y P+ V +I H VP + F VN ++ ++ +N ++ +HC G
Sbjct: 143 TQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHCTHG 202
Query: 247 KGRTGTMVCALLIASE 262
RTG ++C LI E
Sbjct: 203 LNRTGYLICRYLIDVE 218
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 36.2 bits (82), Expect = 0.062
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 211 DHNVPTLHE-MVVFTKEVNEWMAQDLENIVAI-HCKGGKGRTGTMV 254
DH VP+ + ++ F + + +W+ Q +E I HC G GRTGT++
Sbjct: 808 DHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLI 853
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 36.2 bits (82), Expect = 0.062
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 211 DHNVPTLHE-MVVFTKEVNEWMAQDLENIVAI-HCKGGKGRTGTMV 254
DH VP+ + ++ F + + +W+ Q +E I HC G GRTGT++
Sbjct: 986 DHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLI 1031
>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
Length = 383
Score = 35.8 bits (81), Expect = 0.081
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 231 MAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAE 268
+ ++ E +A+HCK G GRTGT++ ++ F AE
Sbjct: 266 ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE 303
>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
Length = 594
Score = 35.8 bits (81), Expect = 0.081
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 231 MAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAE 268
+ ++ E +A+HCK G GRTGT++ ++ F AE
Sbjct: 266 ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE 303
>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
Length = 623
Score = 35.8 bits (81), Expect = 0.081
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 231 MAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAE 268
+ ++ E +A+HCK G GRTGT++ ++ F AE
Sbjct: 266 ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE 303
>gi|30089952 protein tyrosine phosphatase domain containing 1
protein isoform 1 [Homo sapiens]
Length = 806
Score = 35.8 bits (81), Expect = 0.081
Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 3/46 (6%)
Query: 236 ENIVAIHCKGGKGRTGTMV-CALLIASEIFLTAEESLYYFGERRTN 280
E VAIHC G GRTG ++ C L+ A+ +TA++++ + +R N
Sbjct: 235 EGKVAIHCHAGLGRTGVLIACYLVFATR--MTADQAIIFVRAKRPN 278
>gi|30089950 protein tyrosine phosphatase domain containing 1
protein isoform 2 [Homo sapiens]
Length = 754
Score = 35.8 bits (81), Expect = 0.081
Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 3/46 (6%)
Query: 236 ENIVAIHCKGGKGRTGTMV-CALLIASEIFLTAEESLYYFGERRTN 280
E VAIHC G GRTG ++ C L+ A+ +TA++++ + +R N
Sbjct: 183 EGKVAIHCHAGLGRTGVLIACYLVFATR--MTADQAIIFVRAKRPN 226
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.141 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,753,629
Number of Sequences: 37866
Number of extensions: 705720
Number of successful extensions: 2064
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 1988
Number of HSP's gapped (non-prelim): 98
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.