Guide to the Human Genome
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Search of human proteins with 21389473

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389473 transmembrane protein 42 [Homo sapiens]
         (159 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389473 transmembrane protein 42 [Homo sapiens]                   330   4e-91
gi|47827222 solute carrier family 35, member E4 [Homo sapiens]         30   0.67 
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...    28   2.5  
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...    28   2.5  
gi|16933551 anthrax toxin receptor 1 isoform 2 precursor [Homo s...    28   3.3  
gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo s...    28   3.3  
gi|40255283 NHL repeat containing 1 [Homo sapiens]                     28   4.3  
gi|24431939 DnaJ (Hsp40) homolog, subfamily C, member 22 [Homo s...    28   4.3  
gi|110832839 ATP-binding cassette, sub-family C, member 9 isofor...    27   5.6  
gi|110832835 ATP-binding cassette, sub-family C, member 9 isofor...    27   5.6  
gi|110832837 ATP-binding cassette, sub-family C, member 9 isofor...    27   5.6  
gi|28558982 thyroid peroxidase isoform a [Homo sapiens]                27   5.6  
gi|28558984 thyroid peroxidase isoform b [Homo sapiens]                27   5.6  
gi|28558990 thyroid peroxidase isoform e [Homo sapiens]                27   5.6  
gi|46309463 vitamin K epoxide reductase complex, subunit 1-like ...    27   5.6  
gi|50233862 olfactory receptor, family 5, subfamily D, member 13...    27   5.6  
gi|13376097 NIPA-like domain containing 2 [Homo sapiens]               27   7.4  
gi|5453621 solute carrier family 35 (CMP-sialic acid transporter...    27   7.4  
gi|27436867 slit and trk like 4 protein [Homo sapiens]                 27   7.4  
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    27   9.6  
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]       27   9.6  
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]       27   9.6  
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        27   9.6  
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         27   9.6  
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         27   9.6  
gi|4508021 zinc finger protein 259 [Homo sapiens]                      27   9.6  
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                 27   9.6  

>gi|21389473 transmembrane protein 42 [Homo sapiens]
          Length = 159

 Score =  330 bits (845), Expect = 4e-91
 Identities = 159/159 (100%), Positives = 159/159 (100%)

Query: 1   MAERPGPPGGAVSATAYPDTPAEFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLA 60
           MAERPGPPGGAVSATAYPDTPAEFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLA
Sbjct: 1   MAERPGPPGGAVSATAYPDTPAEFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLA 60

Query: 61  FGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVL 120
           FGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVL
Sbjct: 61  FGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVL 120

Query: 121 YGECQEVLWWGGVFLILCGLTLIHRKLPPTWKPLPHKQQ 159
           YGECQEVLWWGGVFLILCGLTLIHRKLPPTWKPLPHKQQ
Sbjct: 121 YGECQEVLWWGGVFLILCGLTLIHRKLPPTWKPLPHKQQ 159


>gi|47827222 solute carrier family 35, member E4 [Homo sapiens]
          Length = 350

 Score = 30.4 bits (67), Expect = 0.67
 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)

Query: 43  CLCAGAFGALAAASAKLAFGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIAS 102
           CL AGA   L A  A      +  +  C+L    ++   S+++   S  L  +++SA+  
Sbjct: 230 CLLAGAALVLEAGVAPPPTAGDSRLWACIL----LSCLLSVLYNLASFSL-LALTSALTV 284

Query: 103 VTVTFSNILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLIH 144
             +    ++ +  L  +L+G     L + G+ L L G+ L H
Sbjct: 285 HVLGNLTVVGNLILSRLLFGSRLSALSYVGIALTLSGMFLYH 326


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score = 28.5 bits (62), Expect = 2.5
 Identities = 28/122 (22%), Positives = 45/122 (36%), Gaps = 25/122 (20%)

Query: 44  LCAGAFGALAAASAKLAFGSEVSMGLCVLGIIVMASTNSL--MWTFFSRGLSFSMSSAIA 101
           LC G+ G + A SA          G+  L I+ M   +     W      +       I 
Sbjct: 86  LCVGSKGQVFATSA--------IRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELIT 137

Query: 102 SVTVTFSNILSSAFLGY------------VLYGECQEVLWWGGVFLILCGLTLIHRKLPP 149
           ++ + F  ++ S++  Y            V +G   + LWWG V +   G      K+P 
Sbjct: 138 TLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIG---YGDKVPQ 194

Query: 150 TW 151
           TW
Sbjct: 195 TW 196


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score = 28.5 bits (62), Expect = 2.5
 Identities = 28/122 (22%), Positives = 45/122 (36%), Gaps = 25/122 (20%)

Query: 44  LCAGAFGALAAASAKLAFGSEVSMGLCVLGIIVMASTNSL--MWTFFSRGLSFSMSSAIA 101
           LC G+ G + A SA          G+  L I+ M   +     W      +       I 
Sbjct: 213 LCVGSKGQVFATSA--------IRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELIT 264

Query: 102 SVTVTFSNILSSAFLGY------------VLYGECQEVLWWGGVFLILCGLTLIHRKLPP 149
           ++ + F  ++ S++  Y            V +G   + LWWG V +   G      K+P 
Sbjct: 265 TLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIG---YGDKVPQ 321

Query: 150 TW 151
           TW
Sbjct: 322 TW 323


>gi|16933551 anthrax toxin receptor 1 isoform 2 precursor [Homo
           sapiens]
          Length = 368

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 61  FGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVT-VTFSNILSSAFLGYV 119
           F  E +  LC   I+      + +    + GLSF  SS I + T  +  +IL+ A L   
Sbjct: 272 FSVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILF 331

Query: 120 LYGECQEVLWWGGVFLILCGLTLIHRKLPP 149
           L      +LWW   F  LC  T+I +++PP
Sbjct: 332 LL-LALALLWW---FWPLC-CTVIIKEVPP 356


>gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo
           sapiens]
          Length = 564

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 61  FGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVT-VTFSNILSSAFLGYV 119
           F  E +  LC   I+      + +    + GLSF  SS I + T  +  +IL+ A L   
Sbjct: 272 FSVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILF 331

Query: 120 LYGECQEVLWWGGVFLILCGLTLIHRKLPP 149
           L      +LWW   F  LC  T+I +++PP
Sbjct: 332 LL-LALALLWW---FWPLC-CTVIIKEVPP 356


>gi|40255283 NHL repeat containing 1 [Homo sapiens]
          Length = 395

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 50  GALAAASAKLAFGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSN 109
           GA+A     LA G+    G+C   + V +S+  L+    + GLS    S I +  VTF +
Sbjct: 274 GAIAVLEHPLALGT----GVCSTRVKVFSSSMQLVGQVDTFGLSLYFPSKITASAVTFDH 329


>gi|24431939 DnaJ (Hsp40) homolog, subfamily C, member 22 [Homo
           sapiens]
          Length = 341

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 7/70 (10%)

Query: 59  LAFGSEVSMGLCVLGIIVMASTNSLMWTFF-----SRGLSFSMSSAIASVTVTFSNILSS 113
           + F ++V +G+   G++ + S +S++  +      + GL   + +A+ + T  F N L S
Sbjct: 79  IRFAAQVIVGI-YFGLVALISLSSMVNFYIVALPLAVGLGVLLVAAVGNQTSDFKNTLGS 137

Query: 114 AFL-GYVLYG 122
           AFL   + YG
Sbjct: 138 AFLTSPIFYG 147


>gi|110832839 ATP-binding cassette, sub-family C, member 9 isoform
           SUR2A-delta-14 [Homo sapiens]
          Length = 1513

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 63  SEVSMGLCVLGII---VMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFL 116
           S +SMG   LG I   V   TN LMW  F     ++M   I    +   N+L S+ L
Sbjct: 401 SNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSAL 457


>gi|110832835 ATP-binding cassette, sub-family C, member 9 isoform
           SUR2A [Homo sapiens]
          Length = 1549

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 63  SEVSMGLCVLGII---VMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFL 116
           S +SMG   LG I   V   TN LMW  F     ++M   I    +   N+L S+ L
Sbjct: 401 SNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSAL 457


>gi|110832837 ATP-binding cassette, sub-family C, member 9 isoform
           SUR2B [Homo sapiens]
          Length = 1549

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 63  SEVSMGLCVLGII---VMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFL 116
           S +SMG   LG I   V   TN LMW  F     ++M   I    +   N+L S+ L
Sbjct: 401 SNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSAL 457


>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
          Length = 933

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 8/69 (11%)

Query: 26  PHLQAGAMRRRFWGVFNCLCA-----GAFGALAAASAKLAFGSEVSMGLCVL---GIIVM 77
           P   A A  R   G F CLCA     G  G     S +L   + +SM L  L   G   +
Sbjct: 806 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 865

Query: 78  ASTNSLMWT 86
            ST    WT
Sbjct: 866 TSTVICRWT 874


>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
          Length = 876

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 8/69 (11%)

Query: 26  PHLQAGAMRRRFWGVFNCLCA-----GAFGALAAASAKLAFGSEVSMGLCVL---GIIVM 77
           P   A A  R   G F CLCA     G  G     S +L   + +SM L  L   G   +
Sbjct: 749 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 808

Query: 78  ASTNSLMWT 86
            ST    WT
Sbjct: 809 TSTVICRWT 817


>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
          Length = 760

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 8/69 (11%)

Query: 26  PHLQAGAMRRRFWGVFNCLCA-----GAFGALAAASAKLAFGSEVSMGLCVL---GIIVM 77
           P   A A  R   G F CLCA     G  G     S +L   + +SM L  L   G   +
Sbjct: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 692

Query: 78  ASTNSLMWT 86
            ST    WT
Sbjct: 693 TSTVICRWT 701


>gi|46309463 vitamin K epoxide reductase complex, subunit 1-like 1
           [Homo sapiens]
          Length = 176

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 17/94 (18%)

Query: 60  AFGSEVSMGLCVLGII-----VMASTNSLMWTFFS-----RGLSFSMSSAIASVTVTFSN 109
           A  S    G  +LG I     V+   NS+    F       G++ S  +A+  +T +  +
Sbjct: 61  ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS 120

Query: 110 ILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLI 143
           ++ S +L Y+LY   +E       F I+C +T +
Sbjct: 121 VVGSLYLAYILYFVLKE-------FCIICIVTYV 147


>gi|50233862 olfactory receptor, family 5, subfamily D, member 13
           [Homo sapiens]
          Length = 314

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 44  LCAGAFGALAAASAKLAFGSEVSMGLCVL---GIIVMASTNSLMWTFFSRGLSFSMSSAI 100
           L A A+    A    L + + +S  LC L   G        SL+ T+F   LSF  S+ I
Sbjct: 117 LAAMAYDRFVAVCKPLLYTTIMSQKLCALLVAGSYTWGIVCSLILTYFLLDLSFCESTFI 176

Query: 101 ASVTVTFSNILSSAF 115
            +     S I+S+++
Sbjct: 177 NNFICDHSVIVSASY 191


>gi|13376097 NIPA-like domain containing 2 [Homo sapiens]
          Length = 368

 Score = 26.9 bits (58), Expect = 7.4
 Identities = 10/17 (58%), Positives = 12/17 (70%)

Query: 125 QEVLWWGGVFLILCGLT 141
           + VLWWGGV L+  G T
Sbjct: 86  KSVLWWGGVLLMAVGET 102


>gi|5453621 solute carrier family 35 (CMP-sialic acid transporter),
           member A1 [Homo sapiens]
          Length = 337

 Score = 26.9 bits (58), Expect = 7.4
 Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 12/107 (11%)

Query: 47  GAFGALAAASAKLAFGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVT 106
           G+ G   A+  +   GS   +    +  +V A  N++ +   S     ++ +A+  VT  
Sbjct: 68  GSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALS-----NLDAAVYQVTYQ 122

Query: 107 FSNILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLIHRKLPPTWKP 153
              I  +A    ++       L W  VF++  G+TL+       WKP
Sbjct: 123 LK-IPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQ------WKP 162


>gi|27436867 slit and trk like 4 protein [Homo sapiens]
          Length = 837

 Score = 26.9 bits (58), Expect = 7.4
 Identities = 12/44 (27%), Positives = 22/44 (50%)

Query: 84  MWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVLYGECQEV 127
           +W F       S ++A + ++V   N+ S   +  VLY  C++V
Sbjct: 3   LWLFLILSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKV 46


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 12/30 (40%), Positives = 15/30 (50%)

Query: 4   RPGPPGGAVSATAYPDTPAEFPPHLQAGAM 33
           RPG  G  +   +YP+ P   P H   GAM
Sbjct: 414 RPGSAGIPMEVGSYPNMPHPQPSHQPPGAM 443


>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
          Length = 765

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 12/31 (38%), Positives = 14/31 (45%)

Query: 8   PGGAVSATAYPDTPAEFPPHLQAGAMRRRFW 38
           PG AV A   P++P   PP    G  R   W
Sbjct: 730 PGEAVPAPTPPESPTPHPPPAAPGGERAGTW 760


>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
          Length = 766

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 12/31 (38%), Positives = 14/31 (45%)

Query: 8   PGGAVSATAYPDTPAEFPPHLQAGAMRRRFW 38
           PG AV A   P++P   PP    G  R   W
Sbjct: 731 PGEAVPAPTPPESPTPHPPPAAPGGERAGTW 761


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 4/31 (12%)

Query: 6    GPPGGAVSATAYPDTPAEFPPHLQAGAMRRR 36
            GP GG +S+T  P   A FP     GA+ +R
Sbjct: 1156 GPEGGVLSSTVVPQVQAVFP----EGALTKR 1182


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 4/31 (12%)

Query: 6    GPPGGAVSATAYPDTPAEFPPHLQAGAMRRR 36
            GP GG +S+T  P   A FP     GA+ +R
Sbjct: 1165 GPEGGVLSSTVVPQVQAVFP----EGALTKR 1191


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 4/31 (12%)

Query: 6    GPPGGAVSATAYPDTPAEFPPHLQAGAMRRR 36
            GP GG +S+T  P   A FP     GA+ +R
Sbjct: 1165 GPEGGVLSSTVVPQVQAVFP----EGALTKR 1191


>gi|4508021 zinc finger protein 259 [Homo sapiens]
          Length = 459

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 2  AERPGPPGGAVSATAYPDTPAEFPPHL 28
          A  PGPPG AV+ +  P  P   P HL
Sbjct: 6  AVEPGPPGAAVAPSPAP-APPPAPDHL 31


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score = 26.6 bits (57), Expect = 9.6
 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 2/32 (6%)

Query: 7   PPGGAVSATAYPDTPAEFP--PHLQAGAMRRR 36
           PPG  ++ TA PD   E P  P +QA    RR
Sbjct: 457 PPGAPLALTALPDPDPEPPGTPEMQAPVASRR 488


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,739,102
Number of Sequences: 37866
Number of extensions: 272164
Number of successful extensions: 1341
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1334
Number of HSP's gapped (non-prelim): 29
length of query: 159
length of database: 18,247,518
effective HSP length: 94
effective length of query: 65
effective length of database: 14,688,114
effective search space: 954727410
effective search space used: 954727410
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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