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Search of human proteins with 113865933
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113865933 PRAME family member 16 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|113865933 PRAME family member 16 [Homo sapiens] 976 0.0
gi|157426839 PRAME family member 17 [Homo sapiens] 974 0.0
gi|194018546 PRAME family member 10 [Homo sapiens] 842 0.0
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 737 0.0
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 737 0.0
gi|154800493 PRAME family member 22 [Homo sapiens] 569 e-162
gi|153791443 PRAME family member 18 [Homo sapiens] 563 e-161
gi|194306638 PRAME family member 3 [Homo sapiens] 563 e-160
gi|194306635 PRAME family member 19 [Homo sapiens] 560 e-159
gi|12738831 PRAME family member 1 [Homo sapiens] 551 e-157
gi|66954681 PRAME family member 13 [Homo sapiens] 542 e-154
gi|12738834 PRAME family member 2 [Homo sapiens] 529 e-150
gi|153792140 PRAME family member 14 [Homo sapiens] 514 e-146
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 491 e-139
gi|124249372 PRAME family member 12 [Homo sapiens] 445 e-125
gi|153792112 PRAME family member 20 [Homo sapiens] 444 e-125
gi|153945800 PRAME family member 21 [Homo sapiens] 444 e-125
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 438 e-123
gi|59676587 PRAME family member 8 [Homo sapiens] 438 e-123
gi|59676593 PRAME family member 7 [Homo sapiens] 436 e-122
gi|148356236 PRAME family member 15 [Homo sapiens] 415 e-116
gi|61102721 PRAME family member 9 [Homo sapiens] 415 e-116
gi|61696142 PRAME family member 5 [Homo sapiens] 410 e-114
gi|58219004 PRAME family member 6 [Homo sapiens] 410 e-114
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 407 e-113
gi|59958373 PRAME family member 4 [Homo sapiens] 406 e-113
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 405 e-113
gi|226437621 PRAME family member 11 [Homo sapiens] 363 e-100
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 352 4e-97
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 352 4e-97
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 976 bits (2523), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 974 bits (2517), Expect = 0.0
Identities = 473/474 (99%), Positives = 473/474 (99%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALSCSPEAM KRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 842 bits (2175), Expect = 0.0
Identities = 415/474 (87%), Positives = 435/474 (91%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FL LPLGSLMKT HLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PR GEHQPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LFLA
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
FGY+ ELYVS Q +PDLD PFLCLYYPQMLYI+KISNIKEHLEHLLR LKNPLG FIF
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
AYL D+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HTGGLSKLGLELYPAPLE LD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 737 bits (1903), Expect = 0.0
Identities = 375/474 (79%), Positives = 391/474 (82%), Gaps = 48/474 (10%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PR GE QPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
R LKNPLG FIF
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
AYL D+DMECLSQYPSLSQLKEL LIHILMWTTNLEPLG LLEKVAATL+ L LKDC+
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HT GLSKLGLELYPAPLE LD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 737 bits (1902), Expect = 0.0
Identities = 375/474 (79%), Positives = 392/474 (82%), Gaps = 48/474 (10%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PR GE QPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
R LKNPLG FIF
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
AYLAD+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HT GLSKLGLELYPAPLE LD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 569 bits (1467), Expect = e-162
Identities = 293/473 (61%), Positives = 353/473 (74%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL+LRDVD NFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F+ YLSQM NLRKLF++
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
G L Q+Q V + L L Y QMLY+R++ + HL+ L+RCL++PL T
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
+ +L D++CL +YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
+RG V E+L P++AELM LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 563 bits (1452), Expect = e-161
Identities = 291/473 (61%), Positives = 349/473 (73%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE ++DE LS+ W+ +RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C + + YLSQM NLRKLF++
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
G Q Q V + FL L Y QMLY+R+I + +L+ L+RCLK+PL T
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
+ L ++D++CL YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
I DS+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
NRG V E+L P++AELM LREVR+P RIFFGP+ CP CG P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 563 bits (1451), Expect = e-160
Identities = 292/473 (61%), Positives = 351/473 (74%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRR KLQVL+LRDVD NFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F YLSQM NLRKLF++
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
G L Q+Q V + L L Y QMLY+R++ + HL+ L+RCL++PL T
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
+ +L D++CL +YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
+RG V E+L P++AELM LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 560 bits (1443), Expect = e-159
Identities = 290/473 (61%), Positives = 348/473 (73%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE ++DE LS+ W+ +RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C + + YLSQM NLRKLF++
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
G Q Q V + FL L Y QMLY+R+I + +L+ L+RCLK+PL T
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
+ L ++D++CL YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
I S+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
NRG V E+L P++AELM LREVR+P RIFFGP+ CP CG P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 551 bits (1421), Expect = e-157
Identities = 288/477 (60%), Positives = 344/477 (72%), Gaps = 8/477 (1%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA S RHF+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALSC PE KRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+K+ NY P R LK +Y +SIQELEI+ K YL +M NLRKL +
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
+ D+EL Q + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 RCHHYTSDNEL----QGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
Query: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+L+ L L
Sbjct: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLIL 356
Query: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
+ CQI SQL +LPALSRCSQLTTFYF N S +ALKDLL HT GLSKL LE YPAP
Sbjct: 357 EGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
Query: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
E L++ VNWEI P+RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 542 bits (1397), Expect = e-154
Identities = 284/477 (59%), Positives = 341/477 (71%), Gaps = 8/477 (1%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA RHF+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALSC PE M KRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+K+ NY P R LK +Y +SIQ+LEI+ K YL +M NLRKL +
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 FGY----DDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
+ D+EL + + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 RCHHSMSDNEL----EGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
Query: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L
Sbjct: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLIL 356
Query: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
+ CQI SQL +LP LS CSQLTTFYF N S ALKDLL HT GLSKL LE YPAP
Sbjct: 357 EGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPE 416
Query: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
E L++ V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 529 bits (1363), Expect = e-150
Identities = 280/477 (58%), Positives = 336/477 (70%), Gaps = 8/477 (1%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +F EA S RHF+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPL SLMKT HLE L+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALSC PEAM KRQT ED PRTGEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+K+ NY P R LK +Y +SI ELEI C + K YL +M L KL +
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
+ D+EL + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 RCHHYTSDNEL----EGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
Query: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
L ++D++CLSQ+PSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L
Sbjct: 297 NLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVL 356
Query: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
+ CQI SQL +LP LS CSQLTTFYF N S +ALKDLL HT GLSKL LE YPAP
Sbjct: 357 EGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
Query: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
E L++ VNWEI P+RAELMCTLRE RQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 514 bits (1324), Expect = e-146
Identities = 270/473 (57%), Positives = 318/473 (67%), Gaps = 48/473 (10%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA RHF+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALSC PE M KRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC+K+ NY P R LK +Y +SIQ+LEI+ K YL +M NLRKL +
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
RCL+NPL
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L+ CQ
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
I SQL +LP LS CSQLTTFYF N S ALKDLLCHT GLSKL LE YPAP E L+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
+ V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 491 bits (1263), Expect = e-139
Identities = 269/462 (58%), Positives = 317/462 (68%), Gaps = 1/462 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRR KLQVL+LRDVD NFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F+PYLSQM NLRKLF++
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
G L Q+Q P FL L+ Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 DGCRYLLSSDSQEQIAP-FTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L DC
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
I DSQ+ +LPALSRC +L TF F GN S L++LL HT L L LELYPAP E
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
G + W IRAELM +R++R PKRI FG CP CG+
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 445 bits (1144), Expect = e-125
Identities = 249/467 (53%), Positives = 312/467 (66%), Gaps = 13/467 (2%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MSLQ+P RLLELA QSLLR++ L I L+ELPRE+FP +FMEA + R E L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F LPLGSLMK+ +LE +AVL+GLD LLAQK+RPRRWKLQVLDLR+VD NFW IWSGA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
ALS PEA+ KR+T + PR G QPL V +DLC K LDECL++ W R+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC ++Q + + +L V D IQE+E+ L+ +FAPYL QM NLRKL L
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 241 FGYDDELYVSG------QQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNP 294
++VS ++QFV FL L Y Q LY+ +S ++ HL+ LLRCL+ P
Sbjct: 239 -----NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAP 293
Query: 295 LGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEIL 354
L T + L++ D++ LS PS+ QLKEL L I + + EPL LLE+ ATL+ L
Sbjct: 294 LETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTL 353
Query: 355 TLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPA 414
L+DC I DSQL +LPALSRCSQL+TF F GN S AL++LL HT GLSKL LELYPA
Sbjct: 354 DLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPA 413
Query: 415 PLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
PLE D +G + W + + AELM TLR++RQPK I F +PCP CG
Sbjct: 414 PLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCG 460
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 444 bits (1142), Expect = e-125
Identities = 247/464 (53%), Positives = 302/464 (65%), Gaps = 4/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR++ L I L+ELP E+FP +FMEA S RH EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FLRLPLGSLMK P ET QAVL GLD LL ++R RRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C P AM R+ V+D PR QPL VFIDLC K TLDE + L W+ R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ M + RN+LK V D IQE+E+ +L +F PYL QM NLRKL L+
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D Y+S +Q +FV FL L Q LY+ +S ++ HL+ +L CLK L
Sbjct: 241 --DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNIL 298
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LS+YPS+ QLK L L + +L PL LLEKVAATLE L L D
Sbjct: 299 AITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDD 358
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +LTTF FRGN ST L++LLCHT L+ L LELYPAP E
Sbjct: 359 CGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRES 418
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
D RG V A + AELM +R +R+P+RI F CP CG+
Sbjct: 419 YDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 444 bits (1142), Expect = e-125
Identities = 247/464 (53%), Positives = 302/464 (65%), Gaps = 4/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR++ L I L+ELP E+FP +FMEA S RH EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
FLRLPLGSLMK P ET QAVL GLD LL ++R RRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C P AM R+ V+D PR QPL VFIDLC K TLDE + L W+ R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ M + RN+LK V D IQE+E+ +L +F PYL QM NLRKL L+
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D Y+S +Q +FV FL L Q LY+ +S ++ HL+ +L CLK L
Sbjct: 241 --DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNIL 298
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LS+YPS+ QLK L L + +L PL LLEKVAATLE L L D
Sbjct: 299 AITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDD 358
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +LTTF FRGN ST L++LLCHT L+ L LELYPAP E
Sbjct: 359 CGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRES 418
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
D RG V A + AELM +R +R+P+RI F CP CG+
Sbjct: 419 YDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 438 bits (1127), Expect = e-123
Identities = 243/463 (52%), Positives = 310/463 (66%), Gaps = 5/463 (1%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELA Q LLR+Q L I ++ELPRE+FP +FMEA S R E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A PEA+ ++QT ++ P TG QP VFIDLC K TLDECL++L W R+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC ++Q + MP S +L V D IQE+E+ L+ KFAPYL QM NLRKL L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
Query: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
F + + QF+ FL L Y Q L + +S ++ HL+ LLRCL+ L
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L++ D++ LS PS+ QLKEL L + + + EPL LLE+V ATL+ L L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQL +LP LSRCSQL+TF F GN S AL++LL HT GLSKL LELYPAPLE
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
D +G + W A + AELM TLR++RQPK I F +PCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 438 bits (1127), Expect = e-123
Identities = 243/463 (52%), Positives = 310/463 (66%), Gaps = 5/463 (1%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELA Q LLR+Q L I ++ELPRE+FP +FMEA S R E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A PEA+ ++QT ++ P TG QP VFIDLC K TLDECL++L W R+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC ++Q + MP S +L V D IQE+E+ L+ KFAPYL QM NLRKL L
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
Query: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
F + + QF+ FL L Y Q L + +S ++ HL+ LLRCL+ L
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L++ D++ LS PS+ QLKEL L + + + EPL LLE+V ATL+ L L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQL +LP LSRCSQL+TF F GN S AL++LL HT GLSKL LELYPAPLE
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
D +G + W A + AELM TLR++RQPK I F +PCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 436 bits (1120), Expect = e-122
Identities = 242/463 (52%), Positives = 309/463 (66%), Gaps = 5/463 (1%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELA Q LLR+Q L I ++ELPRE+FP +FMEA S R E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A PEA+ ++QT ++ P TG QP VFIDLC K TLDECL++L W R+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC ++Q + MP S +L V D IQE+E+ L+ KFAPYL QM NLRKL L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237
Query: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
F + + QF+ FL L Y Q L + +S ++ HL+ LLRCL+ L
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L++ D++ LS PS+ QLKEL L + + + EPL LLE+V ATL+ L L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQL +LP LSRCSQL+TF F GN S AL++LL HT GLSKL LELYPAPLE
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
D +G + W A + AELM T R++RQPK I F +PCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCG 460
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 415 bits (1066), Expect = e-116
Identities = 236/464 (50%), Positives = 293/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL Q +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R ++ V+D PR QPL VF++L K TLDE L+YL W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L +ELYPAP E
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 415 bits (1066), Expect = e-116
Identities = 236/464 (50%), Positives = 293/464 (63%), Gaps = 3/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL Q +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R ++ V+D PR QPL VF++L K TLDE L+YL W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L +ELYPAP E
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 410 bits (1055), Expect = e-114
Identities = 235/464 (50%), Positives = 292/464 (62%), Gaps = 3/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL Q + PRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R ++ V+D PR QPL VF++L K TLDE L+ L W+ R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q L + +S ++ HL+ LL CLK L
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +L TF F GN S L++LL HT L L +ELYPAP E
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
D G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 410 bits (1054), Expect = e-114
Identities = 235/464 (50%), Positives = 291/464 (62%), Gaps = 3/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL Q + PRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R + V+D PR QPL VF++L K TLDE L+ L W+ R+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q L + +S ++ HL+ LL CLK L
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +L TF F GN S L++LL HT L L +ELYPAP E
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
D G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 407 bits (1045), Expect = e-113
Identities = 235/463 (50%), Positives = 287/463 (61%), Gaps = 3/463 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS++ P RLLEL G+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL Q +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R + V+D PR E QPL VF++L K TLDE L+ L W+ RR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL + NL+KL L+
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 278 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L LELYPAP E
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
G + W A IRAELM +R +R PKRI F CP G
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 406 bits (1044), Expect = e-113
Identities = 234/464 (50%), Positives = 290/464 (62%), Gaps = 3/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+ +P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R ++ VED PR QPL VF++L K TLDE L+ L W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L +ELYPAP E
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 405 bits (1042), Expect = e-113
Identities = 233/464 (50%), Positives = 290/464 (62%), Gaps = 3/464 (0%)
Query: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
MS+++P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD LL Q + PRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
A C A R ++ V+D PR QPL VF++L K TLDE L+ L W+ R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
D YVS +Q + V FL L Q L + +S ++ HL+ LL CLK L
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
C I DSQ+ +LPALS C +L TF F GN S L++LL HT L L +ELYPAP E
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
D G + W IRAELM +R++R PKRI F CP CG+
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 363 bits (931), Expect = e-100
Identities = 212/423 (50%), Positives = 256/423 (60%), Gaps = 3/423 (0%)
Query: 41 MEASSMRHFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKL 100
MEA S R EALKLMVQAWPF RLPL L+K P LE QAVL GLD LL Q +RPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLDLRDVDGNFWTIWSGARALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTL 160
QVLDL+DV NFW +WS A A C A R + V+D PR E QPL VF++L K TL
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 161 DECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNK 220
DE L+ L W+ RR L+HLCC K++ MP + R++LK V D IQE+E+ K L
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 221 TGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKIS 278
+F PYL + NL+KL L+ D YVS +Q + V FL L Q LY+ +S
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
Query: 279 NIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLE 338
++ HL+ LL CLK L + L + D++ LSQ PS+SQLK L L I + +L
Sbjct: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
Query: 339 PLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLL 398
PL LLEKVAATLE L L DC I DSQ+ +LPALSRC +L TF F GN L++LL
Sbjct: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
Query: 399 CHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCP 458
HT L L LELYPAP E G + W A IRAELM +R +R PKRI F CP
Sbjct: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
Query: 459 SCG 461
G
Sbjct: 420 DHG 422
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 352 bits (903), Expect = 4e-97
Identities = 213/471 (45%), Positives = 285/471 (60%), Gaps = 15/471 (3%)
Query: 5 SPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRL 64
SP RL+ELAGQSLL+++ L I L+ LPRE+FP +FM A RH + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTPHL--ETLQAVLKGLDTLLAQKLRPRRWKLQVLDLR-DVDGNFWTIWSGARA 121
PLG LMK HL ET +AVL GLD LLAQ++RPRRWKLQVLDLR + +FWT+WSG RA
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MRKRQTVEDYPRTGEHQ--PLKVFIDLCQKESTLDECLSYLCRWIHY 173
S PEA M K++ V+ E P++V +DL KE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +LK V DSI++LE+ L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLFLAFGYDDELYVSGQ--QQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCL 291
LR+L L+ + Y+S + +Q++ FL L Q LY+ + ++ L+ LLR +
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATL 351
NPL T + L++ D+ LSQ PS+SQL L L +++ + EPL ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 EILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLEL 411
+ L +C I D QL LLP+LS CSQLTT F GN S +AL+ LL H GLS L L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPLECL-DNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
YP PLE D G ++ E LA + A L L E+ +P ++ PCP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 352 bits (903), Expect = 4e-97
Identities = 213/471 (45%), Positives = 285/471 (60%), Gaps = 15/471 (3%)
Query: 5 SPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRL 64
SP RL+ELAGQSLL+++ L I L+ LPRE+FP +FM A RH + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTPHL--ETLQAVLKGLDTLLAQKLRPRRWKLQVLDLR-DVDGNFWTIWSGARA 121
PLG LMK HL ET +AVL GLD LLAQ++RPRRWKLQVLDLR + +FWT+WSG RA
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MRKRQTVEDYPRTGEHQ--PLKVFIDLCQKESTLDECLSYLCRWIHY 173
S PEA M K++ V+ E P++V +DL KE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +LK V DSI++LE+ L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLFLAFGYDDELYVSGQ--QQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCL 291
LR+L L+ + Y+S + +Q++ FL L Q LY+ + ++ L+ LLR +
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATL 351
NPL T + L++ D+ LSQ PS+SQL L L +++ + EPL ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 EILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLEL 411
+ L +C I D QL LLP+LS CSQLTT F GN S +AL+ LL H GLS L L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPLECL-DNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
YP PLE D G ++ E LA + A L L E+ +P ++ PCP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,616,336
Number of Sequences: 37866
Number of extensions: 849412
Number of successful extensions: 2447
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2323
Number of HSP's gapped (non-prelim): 51
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.