Guide to the Human Genome
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Search of human proteins with 113428456

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens]
         (358 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens]           740   0.0  
gi|113428072 PREDICTED: similar to mCG141871 [Homo sapiens]           734   0.0  
gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens]           626   e-179
gi|56682966 transforming growth factor, beta receptor III [Homo ...    94   1e-19
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    55   1e-07
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    54   2e-07
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    54   2e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is...    54   3e-07
gi|160707881 formin 2 [Homo sapiens]                                   52   8e-07
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                52   1e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     51   2e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    50   3e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   4e-06
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     49   9e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     49   9e-06
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    49   9e-06
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    49   9e-06
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    49   9e-06
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    49   9e-06
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           49   9e-06
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    48   1e-05
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    48   1e-05
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    48   1e-05
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    48   1e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    48   1e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    48   1e-05
gi|60460889 Myb protein P42POP [Homo sapiens]                          48   1e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    48   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   2e-05
gi|33286436 gametogenetin [Homo sapiens]                               47   2e-05

>gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens]
          Length = 358

 Score =  740 bits (1911), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MGIKQLVEGFASFGGFSRGAWLCNRLSCWAVRVPGVARGHITVRGESGAEPIMGESAAAT 60
           MGIKQLVEGFASFGGFSRGAWLCNRLSCWAVRVPGVARGHITVRGESGAEPIMGESAAAT
Sbjct: 1   MGIKQLVEGFASFGGFSRGAWLCNRLSCWAVRVPGVARGHITVRGESGAEPIMGESAAAT 60

Query: 61  ASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLS 120
           ASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLS
Sbjct: 61  ASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLS 120

Query: 121 DTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLRE 180
           DTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLRE
Sbjct: 121 DTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLRE 180

Query: 181 GCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAH 240
           GCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAH
Sbjct: 181 GCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAH 240

Query: 241 LTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP 300
           LTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP
Sbjct: 241 LTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP 300

Query: 301 GRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGPPV 358
           GRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGPPV
Sbjct: 301 GRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGPPV 358


>gi|113428072 PREDICTED: similar to mCG141871 [Homo sapiens]
          Length = 358

 Score =  734 bits (1894), Expect = 0.0
 Identities = 356/358 (99%), Positives = 356/358 (99%)

Query: 1   MGIKQLVEGFASFGGFSRGAWLCNRLSCWAVRVPGVARGHITVRGESGAEPIMGESAAAT 60
           MGIKQLVEGFASFGGFSRGAWLCNRLSCWAVRVPGVARGHITVRGESGAEPIMGESAAAT
Sbjct: 1   MGIKQLVEGFASFGGFSRGAWLCNRLSCWAVRVPGVARGHITVRGESGAEPIMGESAAAT 60

Query: 61  ASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLS 120
           ASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLS
Sbjct: 61  ASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLS 120

Query: 121 DTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLRE 180
           DTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLRE
Sbjct: 121 DTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLRE 180

Query: 181 GCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAH 240
           GCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPA 
Sbjct: 181 GCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAP 240

Query: 241 LTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP 300
           LTPPPPP PSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP
Sbjct: 241 LTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP 300

Query: 301 GRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGPPV 358
           GRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGPPV
Sbjct: 301 GRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGPPV 358


>gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens]
          Length = 306

 Score =  626 bits (1614), Expect = e-179
 Identities = 304/306 (99%), Positives = 304/306 (99%)

Query: 53  MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 112
           MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR
Sbjct: 1   MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 60

Query: 113 PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 172
           PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG
Sbjct: 61  PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 120

Query: 173 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 232
           PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR
Sbjct: 121 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 180

Query: 233 GVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 292
           GVRRAPA LTPPPPP PSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP
Sbjct: 181 GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 240

Query: 293 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 352
           PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR
Sbjct: 241 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 300

Query: 353 QAGPPV 358
           QAGPPV
Sbjct: 301 QAGPPV 306


>gi|56682966 transforming growth factor, beta receptor III [Homo
           sapiens]
          Length = 851

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 73/246 (29%), Positives = 110/246 (44%), Gaps = 20/246 (8%)

Query: 115 FSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPA 174
           F+++L +T+       G   VP +  V+V+ ++ +     G A+  C ++P S P     
Sbjct: 593 FNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSH 652

Query: 175 LALLREGCPADTSVAFPPPPP---PSPGA-ARPARFSFRLRPVFNASVQFLHCQLSRCRR 230
             ++   CP D SV F  P     P P A     RFSF  +PVFN S+ FL C+L+ C +
Sbjct: 653 YTIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTK 712

Query: 231 LRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPR 290
           +             P  LP +C+P DEAC    S  A  + A   +  T T+P+ V +  
Sbjct: 713 ME----------KHPQKLP-KCVPPDEACT---SLDASIIWAMMQNKKTFTKPLAV-IHH 757

Query: 291 PPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDD 350
                 K    +   P  P P    L+   V+ +  AAFV+GA L   L  + +H+G   
Sbjct: 758 EAESKEKGPSMKEPNPISP-PIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETA 816

Query: 351 LRQAGP 356
            RQ  P
Sbjct: 817 GRQQVP 822


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 84/322 (26%), Positives = 99/322 (30%), Gaps = 56/322 (17%)

Query: 45  GESGAEPIMGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPA 104
           G  G   + G  A A  +       G  G    P    G AR    GP  P PP+P  P 
Sbjct: 56  GALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPA-GRARPGGGGPQRPGPPSPRRPL 114

Query: 105 AP-GPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSV 163
            P GP    P  + KL    +       P+   A      + A A P+   G A      
Sbjct: 115 VPAGP--APP--AAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170

Query: 164 TPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHC 223
            P   P PGP         P        P  P  PGAA+            N S   L+ 
Sbjct: 171 GPGPGPGPGPGPG------PG-------PGKPAGPGAAQ----------TLNGSAALLNS 207

Query: 224 QLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQP 283
             +    +  V   PA L P P P                  +A G     P       P
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKP------------------AAPGTVIQTPPFVGAAAP 249

Query: 284 IVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEP---------APVVALVLAAFVLGAA 334
                P PP  P  + P  A  P PPAPA  A  P         AP V    AA   G+A
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA 309

Query: 335 LAAGLGLVCAHSGTDDLRQAGP 356
            AA      A        Q GP
Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGP 331



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 58/211 (27%), Positives = 79/211 (37%), Gaps = 26/211 (12%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPL---FSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALA 148
           P  P+PPA P PAAP      P     +L         P  A P   P  +     +A A
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGA 311

Query: 149 RPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS---VAFPPPPPPSPGAARPAR 205
            P+P             S +P PG A A    G  A++    V   PP   +  A+ PA 
Sbjct: 312 APAPAPAAG---GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAS 368

Query: 206 FSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSG 265
            +  +  V   ++Q             G   +PA + PPP P     LP+  A A T S 
Sbjct: 369 TAASM--VIGPTMQ-------------GALPSPAAV-PPPAPGTPTGLPKGAAGAVTQSL 412

Query: 266 SAEGLAADGPHLHTLTQPIVV-TVPRPPPRP 295
           S    A       TLT  ++   +P+PP  P
Sbjct: 413 SRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 67/228 (29%), Positives = 83/228 (36%), Gaps = 42/228 (18%)

Query: 97   PPAPPFPAAPGPWL-RRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAA---LARPSP 152
            PP PP P APGP L ++P    + S    V P  A    V   S +  Q A   L  P P
Sbjct: 1627 PPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHA----VTPGSHIHSQTAGHHLPPPPP 1682

Query: 153  RWGLALHRCSVTPSSRPAPGPALALLREGCPAD----TSVAFPPPPPPSPGAARPARFSF 208
              G A       P   P P P+  L  +G  A      + A PPPPPP P +   +    
Sbjct: 1683 PPGPA-------PHHHPPPHPSTGL--QGLQAQHQHVVNSAPPPPPPPPPSSVLASGH-- 1731

Query: 209  RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAE 268
                    S Q LH         +G    P+   P  PP PS+           G G   
Sbjct: 1732 -----HTTSAQALHHPPH-----QGPPLFPSSAHPTVPPYPSQATHH----TTLGPGPQH 1777

Query: 269  GLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAAL 316
              +  GPH      P+ VT P   P+ P S+P        P P   AL
Sbjct: 1778 QPSGTGPHC-----PLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL 1820



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 40/189 (21%), Positives = 59/189 (31%), Gaps = 62/189 (32%)

Query: 187  SVAFPPPPPPSPGAA--------------RPARFSFRLRPVFNASVQFLHCQLSRCRRLR 232
            S A PPPPPP P ++                 + S   + VF +         +  + + 
Sbjct: 1541 STAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVP 1600

Query: 233  GVRRAPAH-----------------LTPPPPPLPSRCLPQDEACADTGSGSAEGLA---- 271
            G    P H                 + PPPPP P+   P         S     +A    
Sbjct: 1601 GHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPA---PGPHLVQQPNSHQQHSVAHVVG 1657

Query: 272  -----ADGPHLHTLTQPIVVTVPRPPPRP-----PKSVPGRAVR--------------PE 307
                   G H+H+ T    +  P PPP P     P   P   ++              P 
Sbjct: 1658 PVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPP 1717

Query: 308  PPAPAPAAL 316
            PP P P+++
Sbjct: 1718 PPPPPPSSV 1726


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 67/228 (29%), Positives = 83/228 (36%), Gaps = 42/228 (18%)

Query: 97   PPAPPFPAAPGPWL-RRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAA---LARPSP 152
            PP PP P APGP L ++P    + S    V P  A    V   S +  Q A   L  P P
Sbjct: 1627 PPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHA----VTPGSHIHSQTAGHHLPPPPP 1682

Query: 153  RWGLALHRCSVTPSSRPAPGPALALLREGCPAD----TSVAFPPPPPPSPGAARPARFSF 208
              G A       P   P P P+  L  +G  A      + A PPPPPP P +   +    
Sbjct: 1683 PPGPA-------PHHHPPPHPSTGL--QGLQAQHQHVVNSAPPPPPPPPPSSVLASGH-- 1731

Query: 209  RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAE 268
                    S Q LH         +G    P+   P  PP PS+           G G   
Sbjct: 1732 -----HTTSAQALHHPPH-----QGPPLFPSSAHPTVPPYPSQATHH----TTLGPGPQH 1777

Query: 269  GLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAAL 316
              +  GPH      P+ VT P   P+ P S+P        P P   AL
Sbjct: 1778 QPSGTGPHC-----PLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL 1820



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 40/189 (21%), Positives = 59/189 (31%), Gaps = 62/189 (32%)

Query: 187  SVAFPPPPPPSPGAA--------------RPARFSFRLRPVFNASVQFLHCQLSRCRRLR 232
            S A PPPPPP P ++                 + S   + VF +         +  + + 
Sbjct: 1541 STAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVP 1600

Query: 233  GVRRAPAH-----------------LTPPPPPLPSRCLPQDEACADTGSGSAEGLA---- 271
            G    P H                 + PPPPP P+   P         S     +A    
Sbjct: 1601 GHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPA---PGPHLVQQPNSHQQHSVAHVVG 1657

Query: 272  -----ADGPHLHTLTQPIVVTVPRPPPRP-----PKSVPGRAVR--------------PE 307
                   G H+H+ T    +  P PPP P     P   P   ++              P 
Sbjct: 1658 PVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPP 1717

Query: 308  PPAPAPAAL 316
            PP P P+++
Sbjct: 1718 PPPPPPSSV 1726


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 67/252 (26%), Positives = 92/252 (36%), Gaps = 38/252 (15%)

Query: 92  PPFPAPPAP--------PFPAAPG-PWLRRPLFSLKLSDTEDVF------PRRAGPLEVP 136
           PP P PP P        P P AP  P    P   LK+   + +       P    P+  P
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP 772

Query: 137 ADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPAL--ALLREGCPADTSVAFPPPP 194
              +   +  +  P+P     +    VT ++ P P P +  A  +   PA      PP P
Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPV-VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP 831

Query: 195 P-PSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCL 253
           P P P    P + SF  +P  +         LS    +  V++  +   PPP P      
Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSP--------LSPVPSV--VKQIASQFPPPPTPPAMESQ 881

Query: 254 PQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRP--PPRPPKSVPGRAVRPEPPAP 311
           P     A+    S   + A         QP  + VP P  PP PP+S       P PP+P
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKW-----QPSSIPVPSPDFPPPPPES--SLVFPPPPPSP 934

Query: 312 APAALEPAPVVA 323
            PA   P P  A
Sbjct: 935 VPAPPPPPPPTA 946



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 52/228 (22%), Positives = 81/228 (35%), Gaps = 17/228 (7%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP P  P P    P    + + +       A P+ V   +   +Q A     
Sbjct: 626 PPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG----SAAPMFVKYSTITRLQNA----- 676

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
                + H  ++     P    + ++  +       V  PPPPPP P     A    +  
Sbjct: 677 -----SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA 731

Query: 212 PVFNASVQF-LHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGL 270
           P   +  QF       +  +++ + +      PPPPP+P+   PQ          +    
Sbjct: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTST 791

Query: 271 AADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEP 318
               P + T   P   T P PP +   + P   + P PP P P  + P
Sbjct: 792 KTVAP-VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPP 837



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 55/195 (28%), Positives = 68/195 (34%), Gaps = 31/195 (15%)

Query: 163 VTPSSRPAPGPALALLREGCPADTSVAFPPPPP------PSPGAARPARFSF----RLRP 212
           VTP +   P P L       P       PPPPP      PS G+A P    +    RL+ 
Sbjct: 616 VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675

Query: 213 VFNASVQFLHCQLSRCRRLRGVRR---------APAHLTPPPPPLPSRCLPQ--DEACAD 261
               S            + + V+           P    PPPPP P   + Q     CA 
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735

Query: 262 TGSGSAEGLAADGPHL--HTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPA 319
               S    +A  P L  H +     V  P PPP PP   P   + P+ P P P    PA
Sbjct: 736 ----SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP---LPPQAP-PKPLVTIPA 787

Query: 320 PVVALVLAAFVLGAA 334
           P     +A  V  AA
Sbjct: 788 PTSTKTVAPVVTQAA 802



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 37/127 (29%), Positives = 47/127 (37%), Gaps = 20/127 (15%)

Query: 95  PAPPAPPFPAAPGPWLRRPLFSLK-----LSDTEDV-------FPRRAGPLEVPADSRVF 142
           P+PP PP P  P    ++  F  K     LS    V       FP    P  + +     
Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885

Query: 143 VQAALARPSPRWGLALHRCSVTPSSRPAPGPAL------ALLREGCPADTSVAFPPPPPP 196
           V A +A  SP    A  +    PSS P P P        + L    P  + V  PPPPPP
Sbjct: 886 VPANVAPQSPPAVKAKPKWQ--PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943

Query: 197 SPGAARP 203
              +  P
Sbjct: 944 PTASPTP 950



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 56/228 (24%), Positives = 78/228 (34%), Gaps = 23/228 (10%)

Query: 88   LSFGPP----FPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFV 143
            L F PP     PAPP PP P A     +      K S T     ++  P     +S +  
Sbjct: 925  LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP-QRNSSIKS 983

Query: 144  QAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARP 203
             +    P P+      R SV         PA      G P+  ++  PP  PP PG    
Sbjct: 984  SSGAEHPEPK------RPSVDSLVSKFTPPA----ESGSPSKETLP-PPAAPPKPGKLNL 1032

Query: 204  ARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLT----PPPPPLPSRCLPQDEAC 259
            +     L  V           +   R    V   P+  +    PPPPP     LP  E  
Sbjct: 1033 S--GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP 1090

Query: 260  ADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPE 307
            A     ++  +A   P     ++  V   P PP RP ++   R  + E
Sbjct: 1091 AVFSGNTSPKVAVVNPQPQQWSKMSVKKAP-PPTRPKRNDSTRLTQAE 1137



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 16/51 (31%), Positives = 19/51 (37%)

Query: 280 LTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFV 330
           +  P   + P PP  PP   P     P PP P P   + AP        FV
Sbjct: 615 IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV 665



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 277 LHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 320
           + ++ +P    VP   P+P    P  A +P PP P P    P P
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP 638



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 24/91 (26%), Positives = 29/91 (31%), Gaps = 34/91 (37%)

Query: 230 RLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVP 289
           R+  + R    L PP  P P    P                       +T +QP   + P
Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTP-----------------------YTASQP---SPP 627

Query: 290 RPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 320
            PPP PP         P PP P P    P P
Sbjct: 628 LPPPPPPP--------PPPPPPPPPPPPPLP 650


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 62/237 (26%), Positives = 74/237 (31%), Gaps = 43/237 (18%)

Query: 92   PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
            PP P    PP P  PG  +  P             P    P   P        A +  P 
Sbjct: 990  PPLPGAGIPPPPPLPGAGIPPP----------PPLPGAGIPPPPPLPG-----AGIPPPP 1034

Query: 152  PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
            P  G  +      P +   P P L       P     A  PPPPP PGA  P        
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----P 1089

Query: 212  PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLA 271
            P+  A +                   P    PPPPPLP   +P        G      L 
Sbjct: 1090 PLPGAGIP-------------PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136

Query: 272  ADG-PHLHTLTQPIVVTVPRPPPRP------PKSVPGRAVRPEPPAPAPAALEPAPV 321
              G P    L +   V +P PPP P      P  +PG  + P PP P      P P+
Sbjct: 1137 GAGIPPPPPLPR---VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 62/256 (24%), Positives = 76/256 (29%), Gaps = 65/256 (25%)

Query: 72   GGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAG 131
            G  +  P  L G+   +   PP P    PP P  PG  +  P             P    
Sbjct: 950  GAAIPPPPPLPGAG--IPLPPPLPGAGIPPPPPLPGAGIPPP----------PPLPGAGI 997

Query: 132  PLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFP 191
            P   P        A +  P P  G  +      P +   P P L       P     A  
Sbjct: 998  PPPPPLPG-----AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1052

Query: 192  PPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSR 251
            PPPPP PGA  P        P+  A +                        PPPPPLP  
Sbjct: 1053 PPPPPLPGAGIPPP-----PPLPGAGI------------------------PPPPPLPGA 1083

Query: 252  CLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPP------RPPKSVPGRAVR 305
             +P        G      L   G             +P PPP       PP  +PG  + 
Sbjct: 1084 GIPPPPPLPGAGIPPPPPLPGVG-------------IPPPPPLPGAGIPPPPPLPGAGIP 1130

Query: 306  PEPPAPAPAALEPAPV 321
            P PP P      P P+
Sbjct: 1131 PPPPLPGAGIPPPPPL 1146



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/173 (27%), Positives = 58/173 (33%), Gaps = 37/173 (21%)

Query: 163  VTPSSRPAPGPALALLREGC-----PADTSVAFPPPPPPSPGAARPARFSFRLRPVFNAS 217
            V P   P PG  +  L         P   +   PPPPPP PGA  P        P+  A 
Sbjct: 876  VPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP-----PPLPGAG 930

Query: 218  VQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHL 277
            +  L                P    PPPPPLP   +P        G      L   G   
Sbjct: 931  ILPLP-------------PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG--- 974

Query: 278  HTLTQPIVVT---VPRPPPRP------PKSVPGRAVRPEPPAPAPAALEPAPV 321
              +  P  +    +P PPP P      P  +PG  + P PP P      P P+
Sbjct: 975  --IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 61/244 (25%), Positives = 74/244 (30%), Gaps = 84/244 (34%)

Query: 78   PGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPA 137
            P  L+G+       PP P    PP P  PG                      AG L +P 
Sbjct: 899  PPPLQGTEMLPPPPPPLPGAGIPPPPPLPG----------------------AGILPLPP 936

Query: 138  DSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPS 197
                   A +  P P  G A+      P   P PG  + L     P     A  PPPPP 
Sbjct: 937  ----LPGAGIPPPPPLPGAAI------PPPPPLPGAGIPL-----PPPLPGAGIPPPPPL 981

Query: 198  PGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDE 257
            PGA  P        P+  A +                        PPPPPLP   +P   
Sbjct: 982  PGAGIPPP-----PPLPGAGI------------------------PPPPPLPGAGIPPPP 1012

Query: 258  ACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALE 317
                 G      L   G             +P PPP     +PG  + P PP P      
Sbjct: 1013 PLPGAGIPPPPPLPGAG-------------IPPPPP-----LPGAGIPPPPPLPGAGIPP 1054

Query: 318  PAPV 321
            P P+
Sbjct: 1055 PPPL 1058



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 58/236 (24%), Positives = 70/236 (29%), Gaps = 63/236 (26%)

Query: 92   PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
            PP P    PP P  PG  +  P             P    P   P        A +  P 
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPP----------PPLPGAGIPPPPPLPG-----AGIPPPP 1078

Query: 152  PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
            P  G  +      P +   P P L  +    P     A  PPPPP PGA  P        
Sbjct: 1079 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP-----P 1133

Query: 212  PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLA 271
            P+  A +                        PPPPPLP   +P        G      L 
Sbjct: 1134 PLPGAGI------------------------PPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169

Query: 272  ADGPHLHTLTQPIVVTVPRPPPRP------PKSVPGRAVRPEPPAPAPAALEPAPV 321
              G             +P PPP P      P  +PG  + P PP P      P P+
Sbjct: 1170 GAG-------------IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1212



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 43/151 (28%), Positives = 62/151 (41%), Gaps = 35/151 (23%)

Query: 187 SVAFPPPPPP---SPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTP 243
           S++ PPPPP    S G  +P       +P  + S +F   Q S    +    +   ++ P
Sbjct: 806 SISQPPPPPSLLWSAGQGQPGS-----QPPHSISTEF---QTSHEHSVSSAFKNSCNI-P 856

Query: 244 PPPPLPSRCLPQDEACADTGSGSAEGLAA---DGPHLHTLTQPIV--VTVPRPPPR---- 294
            PPPLP         C ++ S S  GL       P L  +T P +    +P+PPP     
Sbjct: 857 SPPPLP---------CTESSS-SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE 906

Query: 295 ----PPKSVPGRAVRPEPPAPAPAALEPAPV 321
               PP  +PG  + P PP P    L   P+
Sbjct: 907 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPL 937



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 31/112 (27%), Positives = 35/112 (31%), Gaps = 15/112 (13%)

Query: 92   PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
            PP P    PP P  PG  +  P             PR   P   P        A +  P 
Sbjct: 1122 PPLPGAGIPPPPPLPGAGIPPP----------PPLPRVGIPPPPPLPG-----AGIPPPP 1166

Query: 152  PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARP 203
            P  G  +      P     P P L  +    P     A  PPPPP PG   P
Sbjct: 1167 PLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP 1218


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 55/187 (29%), Positives = 71/187 (37%), Gaps = 32/187 (17%)

Query: 164 TPSSRPAPGPALA-----LLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASV 218
           TP++ PAP PA A      L      + + +  PP P SP   R         P   A V
Sbjct: 506 TPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSP-------PETAAPV 558

Query: 219 QFLHCQLSRCRRLRGVRRAPAHLTPPPPPL-------PSRCLPQDEACADTGSGSAEGLA 271
           +         RR +  R APA  T PPP +       P+  LP       T       L 
Sbjct: 559 E------DMARRTK--RPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLV 610

Query: 272 ADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVL 331
                  T+  P+  T P+P  R  +  P     P P +P PA+  P+PV     A   L
Sbjct: 611 GSSLRAPTVPPPLPPTPPQPARRQSRRSP---ASPSPASPGPAS--PSPVSLSNPAQVDL 665

Query: 332 GAALAAG 338
           GAA A G
Sbjct: 666 GAATAEG 672



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 64/227 (28%), Positives = 84/227 (37%), Gaps = 57/227 (25%)

Query: 93  PFPAPPAPPFPA-APGPWLRRPLFSLKLSDTEDVFPRRAGP--LEVPADSRVFVQ---AA 146
           P PA    P PA AP P       + K     +V PR A P     P ++   V+     
Sbjct: 505 PTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARR 564

Query: 147 LARPSP-RWGLALHRCSVTPSSRPAP---------GPALALLREGCPADTSV-AFPPPPP 195
             RP+P R  +   + S + SS PAP         G   AL R    +       PPP P
Sbjct: 565 TKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLP 624

Query: 196 PSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTP--PPPPLPSRCL 253
           P+P   +PAR                          R  RR+PA  +P  P P  PS   
Sbjct: 625 PTP--PQPAR--------------------------RQSRRSPASPSPASPGPASPSPVS 656

Query: 254 PQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP 300
             + A  D G+ +AEG A +           +  VP PP  PP+  P
Sbjct: 657 LSNPAQVDLGAATAEGGAPEA----------ISGVPTPPAIPPQPRP 693



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 37/144 (25%), Positives = 46/144 (31%), Gaps = 42/144 (29%)

Query: 55  ESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPL 114
           E+AA    + +R +R    R T P      +R        PAPP PP   +PG       
Sbjct: 553 ETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSP-----PAPPLPPGSGSPG------- 600

Query: 115 FSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPA 174
                  T    PRR             V ++L  P           +V P   P P   
Sbjct: 601 -------TPQALPRR------------LVGSSLRAP-----------TVPPPLPPTPPQP 630

Query: 175 LALLREGCPADTSVAFPPPPPPSP 198
                   PA  S A P P  PSP
Sbjct: 631 ARRQSRRSPASPSPASPGPASPSP 654


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 60/218 (27%), Positives = 78/218 (35%), Gaps = 43/218 (19%)

Query: 140 RVFVQAALARPSPRWGLALHRCS-VTPSSRPAPGPALALLREGCPADTSVAFPPP----- 193
           ++  Q A+ R S +  ++    + V P  R A  PA      G PA  + A PPP     
Sbjct: 75  KLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPP 134

Query: 194 PPPSP-GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRC 252
           PPP+P  AA PA                           R  R A A  T PP P P++ 
Sbjct: 135 PPPAPVAAAAPA---------------------------RAPRAAAAAATAPPSPGPAQP 167

Query: 253 LPQDEACADTGS---GSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP 309
            P+ +  A   +     A   A   P       P  V    PP  PP   P    + +PP
Sbjct: 168 GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227

Query: 310 APAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSG 347
            P P   +P P    V A    GAA    L  V  + G
Sbjct: 228 PPQP---QPPPEGGAVRAG---GAARPVSLREVVRYLG 259



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 17/109 (15%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP PAPP PP P A     R P    + +      P   GP +     R    A LA P 
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAP----RAAAAAATAPPSPGPAQ--PGPRAQRAAPLAAPP 181

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGA 200
           P            P++ PA  P     R   PA  +   P PPPP P A
Sbjct: 182 P-----------APAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 77/277 (27%), Positives = 96/277 (34%), Gaps = 61/277 (22%)

Query: 91  GPPFPAPPAPPFPAAPGP---------------------------WLRRPLF-SLKLSDT 122
           G P PAP A P P   GP                            L+RP   SL  S T
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238

Query: 123 EDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC 182
               P R+GP    A       A  ++P P+   AL    VTP  + A  PAL  L    
Sbjct: 239 PLSSPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSSSP 294

Query: 183 PADTSVAFPPPPP--------PSPGAARPARFSFRL-RPVFNASVQFLHCQLSRCRRLRG 233
            A  S + PP P         PSP A  P++ +  L  P   A+  FL            
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP--------- 345

Query: 234 VRRAPAHLTPPPPPLPSRCLPQDEA-CADTGSGSAEGLAADGPHLHTLTQPIVVTVP-RP 291
                   TPPP   P+  LP  +A  +   S     LA   P         ++  P  P
Sbjct: 346 --PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403

Query: 292 PPRPPKSVP-----GRAVRPE--PPAPAPAALEPAPV 321
           PP PP   P        V P   PP+ AP +L   P+
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 86/313 (27%), Positives = 112/313 (35%), Gaps = 68/313 (21%)

Query: 55  ESAAATASLFQRRRRGRGGRVTFPGG--LKGSARFLSF----GPPFPAPP-APPFPAAPG 107
           E +    S   RRR   GG +  P    L  SA  LS     GP     P AP  P+ P 
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 264

Query: 108 PW----LRRPLFSLKLSDTEDVF-PRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCS 162
           P     LR P  +    D      P  + PL  P+ S        A PSP    +L    
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--------APPSPSAPPSLQTLP 316

Query: 163 VTPSSRPA------------------PGPALALLREGCP-ADTSVAFPP-PPPPSPGAAR 202
             P++ P+                  P P L+ L    P A  ++A PP   PPSP A+ 
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376

Query: 203 PARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPP-PPLPSRCLPQDEACAD 261
           P      L P+   S Q              V    A  +PPP PP+ +   P     + 
Sbjct: 377 P------LSPLATPSPQ--------APNALAVHLLQAPFSPPPSPPVQA---PFSPPASP 419

Query: 262 TGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPR------PPKSVPGRAVRP----EPPAP 311
             S SA   +   P L      +  + P  PP       PP++ P  A  P    +PP  
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479

Query: 312 APAALEPAPVVAL 324
           AP AL   P+ AL
Sbjct: 480 APPALATPPLQAL 492



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 79/270 (29%), Positives = 95/270 (35%), Gaps = 53/270 (19%)

Query: 92  PPFPAPP---APPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVP-ADSRVFVQAAL 147
           PP  APP   A P P AP      PL +L         P  + P + P + S     + L
Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPS-------PPASFPGQAPFSPSASLPMSPL 516

Query: 148 ARPSPRWGLALHRCSV-TPSSRPAPGPALALLREGCPA-DTSVAFP-------PPPPPSP 198
           A P P+    L    +  P S PA     A  R   P  DTSV+ P       P PPP P
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576

Query: 199 GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAP---AHLTPPPPPLPSRCLPQ 255
             +  +  S       ++S        S    LRG    P   A  +PPP    + C P 
Sbjct: 577 SRSPSSTLSGPDLAGHSSSAT------STPEELRGYDSGPEGGAAASPPPDAELAACHP- 629

Query: 256 DEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV-----RPEPPA 310
               A    G A  LA  G     L        P PP   P S  G         PE   
Sbjct: 630 ----AAWSRGPAPPLAFRGAPGAPL--------PWPPATGPGSADGLCTIYETEGPESAT 677

Query: 311 PAPAALEPAPVVALVLAAFVLGAALAAGLG 340
           PAP AL+P P      +    G   AAG G
Sbjct: 678 PAPGALDPGP------SPGTSGGKAAAGAG 701


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 75/266 (28%), Positives = 105/266 (39%), Gaps = 38/266 (14%)

Query: 91  GPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFP--RR----AGPLEVPADSRVFVQ 144
           G P PAP A P P   GP  R+ + S     T +  P  RR     G L+ PA SR    
Sbjct: 188 GLPRPAPSARPRPPTEGP--RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSS 244

Query: 145 AALARPSP-RWGLALHRCSVTPS--SRPAPGPALAL--------LREGCPADTSVAFPPP 193
           +A    SP R G +       P+  S+P P    AL         ++  PA   ++  P 
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304

Query: 194 PPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPS--R 251
             PSP AA  ++    L    ++S   L CQL+           P  L PP P  P   +
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSS--SLTCQLA----------TPLPLAPPSPSAPPSLQ 352

Query: 252 CLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPK--SVPGRAVRPEPP 309
            LP   A   + + ++ G          L  P +  +  PPP+ P   ++P     P PP
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 310 APAPAA--LEPAPVVALVLAAFVLGA 333
           A  P +    P+P     LA  +L A
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQA 438



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 79/270 (29%), Positives = 95/270 (35%), Gaps = 53/270 (19%)

Query: 92  PPFPAPP---APPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVP-ADSRVFVQAAL 147
           PP  APP   A P P AP      PL +L         P  + P + P + S     + L
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPS-------PPASFPGQAPFSPSASLPMSPL 555

Query: 148 ARPSPRWGLALHRCSV-TPSSRPAPGPALALLREGCPA-DTSVAFP-------PPPPPSP 198
           A P P+    L    +  P S PA     A  R   P  DTSV+ P       P PPP P
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615

Query: 199 GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAP---AHLTPPPPPLPSRCLPQ 255
             +  +  S       ++S        S    LRG    P   A  +PPP    + C P 
Sbjct: 616 SRSPSSTLSGPDLAGHSSSAT------STPEELRGYDSGPEGGAAASPPPDAELAACHP- 668

Query: 256 DEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV-----RPEPPA 310
               A    G A  LA  G     L        P PP   P S  G         PE   
Sbjct: 669 ----AAWSRGPAPPLAFRGAPGAPL--------PWPPATGPGSADGLCTIYETEGPESAT 716

Query: 311 PAPAALEPAPVVALVLAAFVLGAALAAGLG 340
           PAP AL+P P      +    G   AAG G
Sbjct: 717 PAPGALDPGP------SPGTSGGKAAAGAG 740



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 88/324 (27%), Positives = 112/324 (34%), Gaps = 60/324 (18%)

Query: 55  ESAAATASLFQRRRRGRGGRVTFPGG--LKGSARFLSF----GPPFPAPP-APPFPAAPG 107
           E +    S   RRR   GG +  P    L  SA  LS     GP     P AP  P+ P 
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 108 PW----LRRPLFSLKLSDTEDVF-PRRAGPLEVPADSRVFVQAA---------------- 146
           P     LR P  +    D      P  + PL  P+ S      A                
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ 333

Query: 147 LARPSPRWGLALHRCSVTPS-----SRPAPGPALALLREGCPA-DTSVAFPPPPPPSPGA 200
           LA P P   LA    S  PS     S PA  P+ A    G P    + +F P PP SP A
Sbjct: 334 LATPLP---LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390

Query: 201 ARPARFSFRLR---------PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPP-PPLPS 250
             P +    L          P  +  +  L     +      V    A  +PPP PP+ +
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450

Query: 251 RCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPR------PPKSVPGRAV 304
              P     +   S SA   +   P L      +  + P  PP       PP++ P  A 
Sbjct: 451 ---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 507

Query: 305 RP----EPPAPAPAALEPAPVVAL 324
            P    +PP  AP AL   P+ AL
Sbjct: 508 PPLQLAKPPPQAPPALATPPLQAL 531



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 67/253 (26%), Positives = 83/253 (32%), Gaps = 50/253 (19%)

Query: 88  LSFGPPFP-APPA----PPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVF 142
           L   PP P APP+    P  PA P       L S  L  T    P  + PL   A     
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP--SPPLSPLATPPPQ 395

Query: 143 VQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAF-----PPPPPPS 197
              ALA P  +           P S PA  P   L      A  ++A      P  PPPS
Sbjct: 396 APPALALPPLQ----------APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445

Query: 198 PGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPP---PPLPSRCLP 254
           P    P  FS    P  + S                  +AP  L  PP   PP P    P
Sbjct: 446 PPVQAP--FSPPASPPVSPSAT-------------PPSQAPPSLAAPPLQVPPSPPASPP 490

Query: 255 QDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPA 314
              + A     +   LAA          P+ +  P P   P  + P     P PPA  P 
Sbjct: 491 MSPS-ATPPPQAPPPLAAP---------PLQLAKPPPQAPPALATPPLQALPSPPASFPG 540

Query: 315 ALEPAPVVALVLA 327
               +P  +L ++
Sbjct: 541 QAPFSPSASLPMS 553


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 47/159 (29%), Positives = 58/159 (36%), Gaps = 27/159 (16%)

Query: 165 PSSRPAPGPALALLREG-CPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHC 223
           P + P PG +  ++     P D++   PPPPPP P    P        P           
Sbjct: 574 PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT----- 628

Query: 224 QLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQP 283
            +S    L G         PPPPPLP       E        S  G  A  P       P
Sbjct: 629 AISPPPPLSG-----DATIPPPPPLP-------EGVGIPSPSSLPGGTAIPP-----PPP 671

Query: 284 IVVTVPRPPPRPPKSVPGRAVRPEPPAPAP--AALEPAP 320
           +  +   PPP PP  +PG A  P PP P P  A + P P
Sbjct: 672 LPGSARIPPPPPP--LPGSAGIPPPPPPLPGEAGMPPPP 708



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 60/231 (25%), Positives = 72/231 (31%), Gaps = 74/231 (32%)

Query: 95  PAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRW 154
           P PPAPP P   G  +  P        T    P    P   P    V + +    PS   
Sbjct: 572 PVPPAPPLPGDSGTIIPPP--PAPGDSTTPPPPPPPPPPPPPLPGGVCISSP---PSLPG 626

Query: 155 GLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFP-----PPPPPSPGAARPARFSFR 209
           G A+      P S  A  P    L EG    +  + P     PPPPP PG+AR       
Sbjct: 627 GTAI--SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR------- 677

Query: 210 LRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEG 269
                                          + PPPPPLP               GSA G
Sbjct: 678 -------------------------------IPPPPPPLP---------------GSA-G 690

Query: 270 LAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 320
           +    P       P+      PPP PP    G  + P PP P    + P P
Sbjct: 691 IPPPPP-------PLPGEAGMPPP-PPPLPGGPGIPPPPPFPGGPGIPPPP 733



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 54/223 (24%), Positives = 64/223 (28%), Gaps = 83/223 (37%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP P  PG        SL         P  +G   +P    +     +  PS
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
                +L   +  P   P PG A  +     P   S   PPPPPP PG            
Sbjct: 659 -----SLPGGTAIPPPPPLPGSA-RIPPPPPPLPGSAGIPPPPPPLPG------------ 700

Query: 212 PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLA 271
                                      A + PPPPPLP                      
Sbjct: 701 --------------------------EAGMPPPPPPLPG--------------------- 713

Query: 272 ADGPHLHTLTQPIVVTVPRPPPRP-----PKSVPGRAVRPEPP 309
             GP            +P PPP P     P   PG  + P PP
Sbjct: 714 --GP-----------GIPPPPPFPGGPGIPPPPPGMGMPPPPP 743



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 20/85 (23%)

Query: 236 RAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 295
           RAP    PP PPLP           D+G+     +    P     T P     P PPP P
Sbjct: 570 RAPV---PPAPPLPG----------DSGT-----IIPPPPAPGDSTTP--PPPPPPPPPP 609

Query: 296 PKSVPGRAVRPEPPAPAPAALEPAP 320
           P    G  +   P  P   A+ P P
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPP 634



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 17/42 (40%), Positives = 17/42 (40%), Gaps = 4/42 (9%)

Query: 70  GRGGRVTFPGGLKGSARFLSFGPPFPA----PPAPPFPAAPG 107
           G  G    P  L G A      PP P     PP PPFP  PG
Sbjct: 687 GSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPG 728


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 47/159 (29%), Positives = 58/159 (36%), Gaps = 27/159 (16%)

Query: 165 PSSRPAPGPALALLREG-CPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHC 223
           P + P PG +  ++     P D++   PPPPPP P    P        P           
Sbjct: 583 PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT----- 637

Query: 224 QLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQP 283
            +S    L G         PPPPPLP       E        S  G  A  P       P
Sbjct: 638 AISPPPPLSG-----DATIPPPPPLP-------EGVGIPSPSSLPGGTAIPP-----PPP 680

Query: 284 IVVTVPRPPPRPPKSVPGRAVRPEPPAPAP--AALEPAP 320
           +  +   PPP PP  +PG A  P PP P P  A + P P
Sbjct: 681 LPGSARIPPPPPP--LPGSAGIPPPPPPLPGEAGMPPPP 717



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 60/231 (25%), Positives = 72/231 (31%), Gaps = 74/231 (32%)

Query: 95  PAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRW 154
           P PPAPP P   G  +  P        T    P    P   P    V + +    PS   
Sbjct: 581 PVPPAPPLPGDSGTIIPPP--PAPGDSTTPPPPPPPPPPPPPLPGGVCISSP---PSLPG 635

Query: 155 GLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFP-----PPPPPSPGAARPARFSFR 209
           G A+      P S  A  P    L EG    +  + P     PPPPP PG+AR       
Sbjct: 636 GTAI--SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR------- 686

Query: 210 LRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEG 269
                                          + PPPPPLP               GSA G
Sbjct: 687 -------------------------------IPPPPPPLP---------------GSA-G 699

Query: 270 LAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 320
           +    P       P+      PPP PP    G  + P PP P    + P P
Sbjct: 700 IPPPPP-------PLPGEAGMPPP-PPPLPGGPGIPPPPPFPGGPGIPPPP 742



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 54/223 (24%), Positives = 64/223 (28%), Gaps = 83/223 (37%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP P  PG        SL         P  +G   +P    +     +  PS
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
                +L   +  P   P PG A  +     P   S   PPPPPP PG            
Sbjct: 668 -----SLPGGTAIPPPPPLPGSA-RIPPPPPPLPGSAGIPPPPPPLPG------------ 709

Query: 212 PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLA 271
                                      A + PPPPPLP                      
Sbjct: 710 --------------------------EAGMPPPPPPLPG--------------------- 722

Query: 272 ADGPHLHTLTQPIVVTVPRPPPRP-----PKSVPGRAVRPEPP 309
             GP            +P PPP P     P   PG  + P PP
Sbjct: 723 --GP-----------GIPPPPPFPGGPGIPPPPPGMGMPPPPP 752



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 20/85 (23%)

Query: 236 RAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 295
           RAP    PP PPLP           D+G+     +    P     T P     P PPP P
Sbjct: 579 RAPV---PPAPPLPG----------DSGT-----IIPPPPAPGDSTTP--PPPPPPPPPP 618

Query: 296 PKSVPGRAVRPEPPAPAPAALEPAP 320
           P    G  +   P  P   A+ P P
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPP 643



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 17/42 (40%), Positives = 17/42 (40%), Gaps = 4/42 (9%)

Query: 70  GRGGRVTFPGGLKGSARFLSFGPPFPA----PPAPPFPAAPG 107
           G  G    P  L G A      PP P     PP PPFP  PG
Sbjct: 696 GSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPG 737


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 75/257 (29%), Positives = 94/257 (36%), Gaps = 43/257 (16%)

Query: 74  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 127
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 128 RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 187
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 188 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPA---HLTPP 244
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+       P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPGRA 303
           P   P+   P   A ++      + L A  P    L  P+V  T+ R P  P ++VP   
Sbjct: 508 PTLAPATASPPTTAGSNNPC-LTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPEFP 565

Query: 304 VRPEPPAPAPAALEPAP 320
               PP PAP    P P
Sbjct: 566 CTFLPPTPAPTPPRPPP 582



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 43/148 (29%), Positives = 53/148 (35%), Gaps = 39/148 (26%)

Query: 93  PFPAPPA-PPFPA-----APGPWLRRPLFSLKLSDTEDVF------PRRAGPLEVPADSR 140
           P PAP A PP P      AP P+   P+  L L  +E  F      PR   P   P   +
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPF---PIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQK 504

Query: 141 VF---VQAALARPSPRWGLALHRCSVTPSSRPAPGPAL-------ALLRE-GCPADTSVA 189
                +  A A P    G + + C     +   P  AL        LLR  G P +T   
Sbjct: 505 ASPPTLAPATASPPTTAG-SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563

Query: 190 FP------------PPPPPSPGAARPAR 205
           FP            P PPP P    P+R
Sbjct: 564 FPCTFLPPTPAPTPPRPPPGPATLAPSR 591


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 75/257 (29%), Positives = 94/257 (36%), Gaps = 43/257 (16%)

Query: 74  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 127
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 128 RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 187
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 188 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPA---HLTPP 244
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+       P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPGRA 303
           P   P+   P   A ++      + L A  P    L  P+V  T+ R P  P ++VP   
Sbjct: 508 PTLAPATASPPTTAGSNNPC-LTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPEFP 565

Query: 304 VRPEPPAPAPAALEPAP 320
               PP PAP    P P
Sbjct: 566 CTFLPPTPAPTPPRPPP 582



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 43/148 (29%), Positives = 53/148 (35%), Gaps = 39/148 (26%)

Query: 93  PFPAPPA-PPFPA-----APGPWLRRPLFSLKLSDTEDVF------PRRAGPLEVPADSR 140
           P PAP A PP P      AP P+   P+  L L  +E  F      PR   P   P   +
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPF---PIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQK 504

Query: 141 VF---VQAALARPSPRWGLALHRCSVTPSSRPAPGPAL-------ALLRE-GCPADTSVA 189
                +  A A P    G + + C     +   P  AL        LLR  G P +T   
Sbjct: 505 ASPPTLAPATASPPTTAG-SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563

Query: 190 FP------------PPPPPSPGAARPAR 205
           FP            P PPP P    P+R
Sbjct: 564 FPCTFLPPTPAPTPPRPPPGPATLAPSR 591


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 75/257 (29%), Positives = 94/257 (36%), Gaps = 43/257 (16%)

Query: 74  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 127
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 128 RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 187
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 188 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPA---HLTPP 244
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+       P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPGRA 303
           P   P+   P   A ++      + L A  P    L  P+V  T+ R P  P ++VP   
Sbjct: 508 PTLAPATASPPTTAGSNNPC-LTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPEFP 565

Query: 304 VRPEPPAPAPAALEPAP 320
               PP PAP    P P
Sbjct: 566 CTFLPPTPAPTPPRPPP 582



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 43/148 (29%), Positives = 53/148 (35%), Gaps = 39/148 (26%)

Query: 93  PFPAPPA-PPFPA-----APGPWLRRPLFSLKLSDTEDVF------PRRAGPLEVPADSR 140
           P PAP A PP P      AP P+   P+  L L  +E  F      PR   P   P   +
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPF---PIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQK 504

Query: 141 VF---VQAALARPSPRWGLALHRCSVTPSSRPAPGPAL-------ALLRE-GCPADTSVA 189
                +  A A P    G + + C     +   P  AL        LLR  G P +T   
Sbjct: 505 ASPPTLAPATASPPTTAG-SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563

Query: 190 FP------------PPPPPSPGAARPAR 205
           FP            P PPP P    P+R
Sbjct: 564 FPCTFLPPTPAPTPPRPPPGPATLAPSR 591


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 75/257 (29%), Positives = 94/257 (36%), Gaps = 43/257 (16%)

Query: 74  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 127
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 128 RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 187
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 188 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPA---HLTPP 244
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+       P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPGRA 303
           P   P+   P   A ++      + L A  P    L  P+V  T+ R P  P ++VP   
Sbjct: 508 PTLAPATASPPTTAGSNNPC-LTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPEFP 565

Query: 304 VRPEPPAPAPAALEPAP 320
               PP PAP    P P
Sbjct: 566 CTFLPPTPAPTPPRPPP 582



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 43/148 (29%), Positives = 53/148 (35%), Gaps = 39/148 (26%)

Query: 93  PFPAPPA-PPFPA-----APGPWLRRPLFSLKLSDTEDVF------PRRAGPLEVPADSR 140
           P PAP A PP P      AP P+   P+  L L  +E  F      PR   P   P   +
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPF---PIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQK 504

Query: 141 VF---VQAALARPSPRWGLALHRCSVTPSSRPAPGPAL-------ALLRE-GCPADTSVA 189
                +  A A P    G + + C     +   P  AL        LLR  G P +T   
Sbjct: 505 ASPPTLAPATASPPTTAG-SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563

Query: 190 FP------------PPPPPSPGAARPAR 205
           FP            P PPP P    P+R
Sbjct: 564 FPCTFLPPTPAPTPPRPPPGPATLAPSR 591


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 67/248 (27%), Positives = 80/248 (32%), Gaps = 42/248 (16%)

Query: 96  APPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVF-VQAALARPSPRW 154
           APP PP PAAP                    P  A P+      +++ + AA A P P  
Sbjct: 719 APPGPPGPAAPPA------------------PSPAAPVRTRRRRKLYELHAAGAPPPPPP 760

Query: 155 GLALHRCSVTPSSRPAPGPALALLRE-GCPADTSVAFPPPP-PPSPGAARPARFSFRLRP 212
           G A    S  P S    GP LA  R  G  AD  +     P  P PGA  PA   +    
Sbjct: 761 GHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECT 820

Query: 213 VFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACAD------TGSGS 266
               S   L   L+  +        P  L  P    P  C P      D         G 
Sbjct: 821 ACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACP-YCPPNGPVRGDLLEHFRLAHGL 879

Query: 267 AEGLAADGPHLHTLTQ----PIVVTVPRPPPRPPKSVPGRAVRPEP----------PAPA 312
             G    GP +   T     P     P   P+P    P   + PEP          PA A
Sbjct: 880 LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAA 939

Query: 313 PAALEPAP 320
           P A+ P P
Sbjct: 940 PEAVPPPP 947



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 46/145 (31%), Positives = 54/145 (37%), Gaps = 30/145 (20%)

Query: 192 PPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSR 251
           PP PP P AA PA       P   A V        R RR R +    A   PPPPP P  
Sbjct: 720 PPGPPGP-AAPPA-------PSPAAPV--------RTRRRRKLYELHAAGAPPPPP-PGH 762

Query: 252 CLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAP 311
               +     +GSGS  GLA                 P P    P  +  +  RP P AP
Sbjct: 763 APAPESPRPGSGSGSGPGLAP-------------ARSPGPAADGPIDLSKKPRRPLPGAP 809

Query: 312 APAALEPAPVVALVLAAFVLGAALA 336
           APA  +     A  ++   L A LA
Sbjct: 810 APALADYHECTACRVSFHSLEAYLA 834



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 45/168 (26%), Positives = 58/168 (34%), Gaps = 52/168 (30%)

Query: 198 PGAARPARFSFRLRPVF-NASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQD 256
           PGA + A   F     F N +  ++H +L  C   R    APA   P  PP P+R  P  
Sbjct: 571 PGAPKGAT-CFECEITFSNVNNYYVHKRLY-CSGRRAPEDAPAARRPKAPPGPARAPPGQ 628

Query: 257 EACADT------------GSGSA------------EGLAADGPHL--------HTLTQPI 284
            A  D             G+G A            EG  + G  +         TL +  
Sbjct: 629 PAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEAC 688

Query: 285 VVTVPR-----------------PPPRPPKSVPGRAVRPEPPAPAPAA 315
            +   R                 PPPR P + PG      PPAP+PAA
Sbjct: 689 NIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAA 736



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 45/152 (29%), Positives = 51/152 (33%), Gaps = 24/152 (15%)

Query: 197 SPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQD 256
           SPGA  PA    +L P    S Q  H  L        +  AP     P P L  + L + 
Sbjct: 384 SPGAGHPAT---KLPPDSLGSFQQQHTALQGPLASADLGLAPT----PSPGLDRKALAE- 435

Query: 257 EACADTGSGSAEGLAADGPHLHTLTQPI---VVTVPRP-------PPRPPKSVPGRAVRP 306
              A  G   AE LA +G        P    V  V  P       P  P    P R   P
Sbjct: 436 ---ATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSP 492

Query: 307 EPPAPAPAALE---PAPVVALVLAAFVLGAAL 335
             PAPA    E   P P  + V     L  AL
Sbjct: 493 RSPAPARVKAELSSPTPGSSPVPGELGLAGAL 524



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 2/31 (6%)

Query: 289 PRPPPRPPKSVPGRAVRPEPP--APAPAALE 317
           P+ PP P ++ PG+   P+ P  +P P A E
Sbjct: 615 PKAPPGPARAPPGQPAEPDAPRSSPGPGARE 645


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 21/139 (15%)

Query: 191 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTP----P 244
           PPPPPP  GA  A+P        P   +S   L   +    +     R P  ++P    P
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV 304
           PPPLPS         + T +          P    L  P V     PPP P +  PG  +
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP----PPPAPLQIAPG-VL 382

Query: 305 RPEPPAPAPAALEPAPVVA 323
            P PP  AP  ++P+P VA
Sbjct: 383 HPAPPPIAPPLVQPSPPVA 401



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 60/237 (25%), Positives = 77/237 (32%), Gaps = 55/237 (23%)

Query: 93  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 152
           P   PP PP   A      +P+ +   S T  +  R   P      + VFV      P P
Sbjct: 275 PHEPPPPPPMHGAGDA---KPIPTCISSATGLIENRPQSP--ATGRTPVFVSPTPPPPPP 329

Query: 153 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRP 212
               AL   S+  S    P P +               PPPPPP+     PA       P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVP--------------PPPPPPATALQAPAV------P 369

Query: 213 VFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAA 272
              A +Q                 AP  L P PPP+    +      A            
Sbjct: 370 PPPAPLQI----------------APGVLHPAPPPIAPPLVQPSPPVARAAP------VC 407

Query: 273 DGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 323
           +   +H L Q  V  +P PPP  P  +P   +RP  P      A  P+ L P P  A
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPP--PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/113 (32%), Positives = 41/113 (36%), Gaps = 21/113 (18%)

Query: 240 HLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 296
           H  PPPPP+       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 276 HEPPPPPPMHG---AGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 297 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 334
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 45/166 (27%), Positives = 58/166 (34%), Gaps = 32/166 (19%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 212 PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDE 257
           P    +V  L    S           P H+   PP  PS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPSTAPGP-HVPLMPPSPPSQVIPASE 483


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 21/139 (15%)

Query: 191 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTP----P 244
           PPPPPP  GA  A+P        P   +S   L   +    +     R P  ++P    P
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV 304
           PPPLPS         + T +          P    L  P V     PPP P +  PG  +
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP----PPPAPLQIAPG-VL 382

Query: 305 RPEPPAPAPAALEPAPVVA 323
            P PP  AP  ++P+P VA
Sbjct: 383 HPAPPPIAPPLVQPSPPVA 401



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 60/237 (25%), Positives = 77/237 (32%), Gaps = 55/237 (23%)

Query: 93  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 152
           P   PP PP   A      +P+ +   S T  +  R   P      + VFV      P P
Sbjct: 275 PHEPPPPPPMHGAGDA---KPIPTCISSATGLIENRPQSP--ATGRTPVFVSPTPPPPPP 329

Query: 153 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRP 212
               AL   S+  S    P P +               PPPPPP+     PA       P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVP--------------PPPPPPATALQAPAV------P 369

Query: 213 VFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAA 272
              A +Q                 AP  L P PPP+    +      A            
Sbjct: 370 PPPAPLQI----------------APGVLHPAPPPIAPPLVQPSPPVARAAP------VC 407

Query: 273 DGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 323
           +   +H L Q  V  +P PPP  P  +P   +RP  P      A  P+ L P P  A
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPP--PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/113 (32%), Positives = 41/113 (36%), Gaps = 21/113 (18%)

Query: 240 HLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 296
           H  PPPPP+       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 276 HEPPPPPPMHG---AGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 297 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 334
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 45/166 (27%), Positives = 58/166 (34%), Gaps = 32/166 (19%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 212 PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDE 257
           P    +V  L    S           P H+   PP  PS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPSTAPGP-HVPLMPPSPPSQVIPASE 483


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 21/139 (15%)

Query: 191 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTP----P 244
           PPPPPP  GA  A+P        P   +S   L   +    +     R P  ++P    P
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV 304
           PPPLPS         + T +          P    L  P V     PPP P +  PG  +
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP----PPPAPLQIAPG-VL 382

Query: 305 RPEPPAPAPAALEPAPVVA 323
            P PP  AP  ++P+P VA
Sbjct: 383 HPAPPPIAPPLVQPSPPVA 401



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 60/237 (25%), Positives = 77/237 (32%), Gaps = 55/237 (23%)

Query: 93  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 152
           P   PP PP   A      +P+ +   S T  +  R   P      + VFV      P P
Sbjct: 275 PHEPPPPPPMHGAGDA---KPIPTCISSATGLIENRPQSP--ATGRTPVFVSPTPPPPPP 329

Query: 153 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRP 212
               AL   S+  S    P P +               PPPPPP+     PA       P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVP--------------PPPPPPATALQAPAV------P 369

Query: 213 VFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAA 272
              A +Q                 AP  L P PPP+    +      A            
Sbjct: 370 PPPAPLQI----------------APGVLHPAPPPIAPPLVQPSPPVARAAP------VC 407

Query: 273 DGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 323
           +   +H L Q  V  +P PPP  P  +P   +RP  P      A  P+ L P P  A
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPP--PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/113 (32%), Positives = 41/113 (36%), Gaps = 21/113 (18%)

Query: 240 HLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 296
           H  PPPPP+       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 276 HEPPPPPPMHG---AGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 297 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 334
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 45/166 (27%), Positives = 58/166 (34%), Gaps = 32/166 (19%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 212 PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDE 257
           P    +V  L    S           P H+   PP  PS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPSTAPGP-HVPLMPPSPPSQVIPASE 483


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 21/139 (15%)

Query: 191 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTP----P 244
           PPPPPP  GA  A+P        P   +S   L   +    +     R P  ++P    P
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 245 PPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV 304
           PPPLPS         + T +          P    L  P V     PPP P +  PG  +
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP----PPPAPLQIAPG-VL 382

Query: 305 RPEPPAPAPAALEPAPVVA 323
            P PP  AP  ++P+P VA
Sbjct: 383 HPAPPPIAPPLVQPSPPVA 401



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 60/237 (25%), Positives = 77/237 (32%), Gaps = 55/237 (23%)

Query: 93  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 152
           P   PP PP   A      +P+ +   S T  +  R   P      + VFV      P P
Sbjct: 275 PHEPPPPPPMHGAGDA---KPIPTCISSATGLIENRPQSP--ATGRTPVFVSPTPPPPPP 329

Query: 153 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRP 212
               AL   S+  S    P P +               PPPPPP+     PA       P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVP--------------PPPPPPATALQAPAV------P 369

Query: 213 VFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAA 272
              A +Q                 AP  L P PPP+    +      A            
Sbjct: 370 PPPAPLQI----------------APGVLHPAPPPIAPPLVQPSPPVARAAP------VC 407

Query: 273 DGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 323
           +   +H L Q  V  +P PPP  P  +P   +RP  P      A  P+ L P P  A
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPP--PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/113 (32%), Positives = 41/113 (36%), Gaps = 21/113 (18%)

Query: 240 HLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 296
           H  PPPPP+       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 276 HEPPPPPPMHG---AGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 297 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 334
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 45/166 (27%), Positives = 58/166 (34%), Gaps = 32/166 (19%)

Query: 92  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 151
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 152 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 211
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 212 PVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDE 257
           P    +V  L    S           P H+   PP  PS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPSTAPGP-HVPLMPPSPPSQVIPASE 483


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 70/233 (30%), Positives = 85/233 (36%), Gaps = 22/233 (9%)

Query: 93  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 152
           P P P  PPFP   G  L     S++ S      P    P   P  SR         P P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGG--SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270

Query: 153 RWGL-ALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSF--- 208
                ++HR +V P       P +       P+ +S A PPPPPPS     P   S    
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPR--PSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 209 ----RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPP---PPLPSRCLPQDEACAD 261
               RL P  N S+      L    R   +   P+   PPP   PP  S  LP     + 
Sbjct: 329 DETPRL-PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387

Query: 262 TGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPA 314
            GS S    A   P L + +    V  PR  PRPP   P R     PP P P+
Sbjct: 388 NGSTSRALPAT--PQLPSRSG---VDSPRSGPRPPLP-PDRPSAGAPPPPPPS 434



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 72/269 (26%), Positives = 93/269 (34%), Gaps = 50/269 (18%)

Query: 78  PGGLKGSARFLSFGPP-----FPAPPAPPFPAAPGPWLRR-PLFSLKLSDTEDVFPRRAG 131
           PGG   SA+   F PP     FP P        P P   R P     +    D  P    
Sbjct: 131 PGGRSTSAK--PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP--- 185

Query: 132 PLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC----PADTS 187
              VP+  R    +   R SP       + S  P+  P PG     L  G     P  +S
Sbjct: 186 --PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243

Query: 188 VAFP----------------PPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRL 231
             F                 PPPPP P   RP+        +   +V     Q ++    
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS--------IHREAVPPPPPQNNKPPVP 295

Query: 232 RGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV---TV 288
              R + +   PPPPP PSR  P     + +G+     L      L + T P+     + 
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355

Query: 289 PRPPP---RPPKSV---PGRAVRPEPPAP 311
           P PPP   RPP  V   PGR+    PP P
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPP 384


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 70/233 (30%), Positives = 85/233 (36%), Gaps = 22/233 (9%)

Query: 93  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 152
           P P P  PPFP   G  L     S++ S      P    P   P  SR         P P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGG--SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270

Query: 153 RWGL-ALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSF--- 208
                ++HR +V P       P +       P+ +S A PPPPPPS     P   S    
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPR--PSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 209 ----RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPP---PPLPSRCLPQDEACAD 261
               RL P  N S+      L    R   +   P+   PPP   PP  S  LP     + 
Sbjct: 329 DETPRL-PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387

Query: 262 TGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPA 314
            GS S    A   P L + +    V  PR  PRPP   P R     PP P P+
Sbjct: 388 NGSTSRALPAT--PQLPSRSG---VDSPRSGPRPPLP-PDRPSAGAPPPPPPS 434



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 72/269 (26%), Positives = 93/269 (34%), Gaps = 50/269 (18%)

Query: 78  PGGLKGSARFLSFGPP-----FPAPPAPPFPAAPGPWLRR-PLFSLKLSDTEDVFPRRAG 131
           PGG   SA+   F PP     FP P        P P   R P     +    D  P    
Sbjct: 131 PGGRSTSAK--PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP--- 185

Query: 132 PLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC----PADTS 187
              VP+  R    +   R SP       + S  P+  P PG     L  G     P  +S
Sbjct: 186 --PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243

Query: 188 VAFP----------------PPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRL 231
             F                 PPPPP P   RP+        +   +V     Q ++    
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS--------IHREAVPPPPPQNNKPPVP 295

Query: 232 RGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV---TV 288
              R + +   PPPPP PSR  P     + +G+     L      L + T P+     + 
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355

Query: 289 PRPPP---RPPKSV---PGRAVRPEPPAP 311
           P PPP   RPP  V   PGR+    PP P
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPP 384


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 73/263 (27%), Positives = 88/263 (33%), Gaps = 68/263 (25%)

Query: 97  PPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGL 156
           PPA P    P P      + L     ED   RRA       D+    +A  + P P W  
Sbjct: 136 PPAAPSSQPPPPSACPQRYVLSEDRRED---RRA-------DTSAHSKAGSSSPEP-WA- 183

Query: 157 ALHRCSVTPSSRPAPGPALALLREGCPADT--SVAFP----PPPPPSPGAARPARFSFRL 210
              R S TP     P P     RE  P      V  P     PPPP+P    P   +   
Sbjct: 184 ---RPSCTPQEGGCPRPKE---RESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLA--- 234

Query: 211 RPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGL 270
                                   + AP+  +PPPPP P   L   +   D      E  
Sbjct: 235 ------------------------QVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETA 270

Query: 271 AADGPHLHTLTQ-------------PIVVTVP---RPPPRPPKSVPGRAVRPEPPAPAPA 314
            A      TL Q             P++   P    PPP PP   P    RP  P PAP 
Sbjct: 271 NAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAP- 329

Query: 315 ALEPAPVVALVLAAFVLGAALAA 337
            +E  P    V+AA V GA +AA
Sbjct: 330 KVEITPEPVSVVAAVVDGAVVAA 352



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 40/153 (26%), Positives = 52/153 (33%), Gaps = 19/153 (12%)

Query: 172 GPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRL 231
           GP +A    G  A+   A P   PP P A  P R+              L       RR 
Sbjct: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSAC-PQRY-------------VLSEDRREDRRA 166

Query: 232 RGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRP 291
                + A  + P P     C PQ+  C       +   +A    L  +  P +   P P
Sbjct: 167 DTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSA----LQPVQLPRLALSPPP 222

Query: 292 PPRP-PKSVPGRAVRPEPPAPAPAALEPAPVVA 323
           P  P P   P   V P PP+P P    P  + A
Sbjct: 223 PAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSA 255



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 19/175 (10%)

Query: 88  LSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGP-LEVPADSRVFVQAA 146
           L+  PP PAPP PP P         PL  +  S      P R  P L     S  F++A 
Sbjct: 216 LALSPPPPAPPLPPPP---------PLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQ 266

Query: 147 LARPSPRWGLA-LHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPA- 204
               +    LA   R  +   S      AL  L  G P D+     PPPPP P   RP  
Sbjct: 267 QETANAIRELAGTLRQGLAKLSEAL--SALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVL 324

Query: 205 -----RFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLP 254
                +      PV   +       ++    +   R       PPP PLP    P
Sbjct: 325 PPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSP 379


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 55/159 (34%), Positives = 60/159 (37%), Gaps = 23/159 (14%)

Query: 45  GESGAEPIMGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPA 104
           GE  A P  G S AA    F +  RGRG    FPG + G  RF   GP  P  P PPFPA
Sbjct: 182 GEGKAGPPGGSSRAA----FPQGGRGRG---RFPGAVPGGDRFP--GPAGPGGPPPPFPA 232

Query: 105 APGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVT 164
              P  R PL            P   GP   P   +V +   LA P  R         V 
Sbjct: 233 GQTP-PRPPLGP----------PGPPGPPGPPPPGQV-LPPPLAGPPNRGDRP--PPPVL 278

Query: 165 PSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARP 203
              +P   P L  L  G P       PPP PP P    P
Sbjct: 279 FPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 10/83 (12%)

Query: 238 PAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRP------ 291
           PA  TPP PPL     P        G      LA   P+      P V+   +P      
Sbjct: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP-PNRGDRPPPPVLFPGQPFGQPPL 289

Query: 292 ---PPRPPKSVPGRAVRPEPPAP 311
              PP PP  VPG    P PP P
Sbjct: 290 GPLPPGPPPPVPGYGPPPGPPPP 312



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 27/93 (29%), Positives = 30/93 (32%), Gaps = 15/93 (16%)

Query: 243 PPPPPLPSRCLPQDEACADTGS----------GSAEGLAADGPHLHTLTQPIVVTVPRPP 292
           PP PP P + LP   A                G   G    GP       P+    P P 
Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308

Query: 293 PRPPKSVPGRAVRPEPPAP-----APAALEPAP 320
           P PP+  P     P PP P      P  L P P
Sbjct: 309 PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP 341


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 64/239 (26%), Positives = 80/239 (33%), Gaps = 16/239 (6%)

Query: 91   GPPFPAPPAPPFPAAPGP-----WLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQA 145
            GP  P+P   P P A  P      L  P      +      P   G L  P         
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152

Query: 146  ALARPSPRWGLAL---HRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAAR 202
            A   PSP+ GLA         TP++ P P P   L         +     PP P  G A 
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211

Query: 203  PARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADT 262
            P   S +  P   A+              +G    PA   P P   P+   P+       
Sbjct: 1212 P---SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268

Query: 263  GSG-SAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 320
             +  S +G  A  PH      P VVT P P   P  S P  A  P PPA  P + + +P
Sbjct: 1269 ATPPSLKGGLATPPHKGA-PNPAVVTPPSPKGGPATSPPKGA--PTPPAATPPSPKGSP 1324



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 65/255 (25%), Positives = 87/255 (34%), Gaps = 47/255 (18%)

Query: 71   RGGRVTFPGGLKGSARFLSFGPPFP--APPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPR 128
            +GG  T P   KG+    +  PP P  +P  PP   AP P    P             P 
Sbjct: 1298 KGGPATSPP--KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP-------------PS 1342

Query: 129  RAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALAL-LREGCPADTS 187
              G   +PA +          PS + G        TPSS+  P P  A    +G PA T 
Sbjct: 1343 PKGTPTLPATT----------PSSKGG------PTTPSSKEGPTPPAATPSHKGGPAMT- 1385

Query: 188  VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPP 247
                 PP P  G A P   S +  P   A +     +       R     P+     PP 
Sbjct: 1386 -----PPSPKRGPAIP---SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437

Query: 248  LPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPE 307
            +    L +  A +    G A   +   P L  +T P     P+ PP P +     + +  
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS----PKEPPAPKQVATSSSPKKA 1493

Query: 308  PPAPAPAALEPAPVV 322
            P  PAP      P V
Sbjct: 1494 PATPAPMGAPTLPAV 1508



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 64/237 (27%), Positives = 81/237 (34%), Gaps = 36/237 (15%)

Query: 95   PAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRV---FVQAALARPS 151
            P PP+P    AP P    PL     S      P    P E P  S V   F +   A P+
Sbjct: 856  PTPPSPK--GAPTPSAVTPL-----SPKGVTLP----PKETPTPSVVNLPFPKEGPATPA 904

Query: 152  PRWGLALHRCSVTPS-SRPAPGPALALLREGCPADTSVAFPPPPP----PSPGAARPARF 206
            P+   AL   S +P  +R  P P      +G PA  S    P PP    PSP    PA  
Sbjct: 905  PKQAPALSMTSSSPKKARATPAP------KGIPASPSPKGAPTPPAATPPSPKGG-PATP 957

Query: 207  SFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGS 266
            S +  P   A+              +G    PA   P P   P+   P+       G+ +
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK-------GAPT 1010

Query: 267  AEGLAADGPHLHTLTQPIVVTVPRPP---PRPPKSVPGRAVRPEPPAPAPAALEPAP 320
               +    P       P       PP   P  PK  P     P+     PAA  P+P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 60/250 (24%), Positives = 79/250 (31%), Gaps = 63/250 (25%)

Query: 91   GPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARP 150
            GP  P+P   P P A  P                  P   G    P+        A+  P
Sbjct: 976  GPATPSPKGAPTPPAATP------------------PSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 151  SPRWGLA---LHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFS 207
            SP+   A     + + TP +   P P      +G PA T +  P   P +P A  P+   
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSP------KGSPAATPL--PKGAPTTPAATLPSPKG 1069

Query: 208  FRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGS-GS 266
                P                  L+G    PA   P P   P+   P+        +  S
Sbjct: 1070 GPATP-----------------SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112

Query: 267  AEGLAADGPHLHTLTQPIVVT------VPRPPPR---------PPKSVPGRAVRPEPPAP 311
             +G  A  PH    T P          +  PPP+         PP    G A  P   AP
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172

Query: 312  -APAALEPAP 320
              PAA  P+P
Sbjct: 1173 TTPAATPPSP 1182



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 69/266 (25%), Positives = 91/266 (34%), Gaps = 44/266 (16%)

Query: 95   PAPPAPPFPAAPG-PWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPR 153
            P PPA   P+  G P L     S K   T      + GP    A        A+  PSP+
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTP--SSKEGPTPPAATPSHKGGPAMTPPSPK 1390

Query: 154  WGLALHRCSVTPSS------RPAPGPALALLREGC----------PADTSVAFPPPPPPS 197
             G A+      P+S       P   PA  + REG           PA T V+    P  S
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450

Query: 198  PGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR---GVRRAPAHLTPPP---PPLPSR 251
                 PA  S +  P   A       +    +++      ++APA  TP P   P LP+ 
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA--TPAPMGAPTLPAV 1508

Query: 252  CLPQDEACADTGSGSAEGLAADGPHLHTLTQ----------PIVVTVPRPPPRP----PK 297
                 +    T S   + +A     L   T           P  +TVP P   P    PK
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568

Query: 298  SVPGRAVRPE---PPAPAPAALEPAP 320
              P      E   PPA  P+  + AP
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAP 1594


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 76/289 (26%), Positives = 100/289 (34%), Gaps = 56/289 (19%)

Query: 58  AATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSL 117
           AA++SL  +   G GG     GGL  ++  +S+       P PP  A P   + R     
Sbjct: 257 AASSSLAAKASLGGGGG----GGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEA 312

Query: 118 KLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRP------AP 171
           +  D +      +GP   PA        A A P P +       +  P S+P      AP
Sbjct: 313 EGGDGDG--EGCSGPPSAPASQ------ARALPPPPY-------TTFPGSKPKFDWVSAP 357

Query: 172 ------------GPALALLREGCPADTSVAFPPPPPP-----SPGAARPARFSFRLRPVF 214
                       G  +   R    A +     PPPPP     +PG  RPA       P  
Sbjct: 358 DGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPA-------PAL 410

Query: 215 NASVQFLHCQLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADG 274
            A   F+    +    +R        L P PPP P   L Q  A   T    A  L    
Sbjct: 411 LAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTL-QPPALQPTPLPVAPPLTPGL 469

Query: 275 PHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVA 323
            H  +   P        P  PP     +A  P P APAP   EP+P V+
Sbjct: 470 GHKESALAPTAA-----PALPPALAADQAPAPSP-APAPTVAEPSPPVS 512



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 58/230 (25%), Positives = 87/230 (37%), Gaps = 41/230 (17%)

Query: 67  RRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPP--FPAAPGPWLRRPLFSLKLSDTED 124
           R  G GG +  P       R  +   P+ +PP PP    +APGP  RRP  +L L+    
Sbjct: 365 RFNGAGGGIGAP-----RRRAAALSGPWGSPPPPPEQIHSAPGP--RRPAPAL-LAPPTF 416

Query: 125 VFPR-------RAGPLEV-------PADSRVFVQAALARPSP-------RWGLALHRCSV 163
           +FP        R GP  +       P      +Q    +P+P         GL     ++
Sbjct: 417 IFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESAL 476

Query: 164 TPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHC 223
            P++ PA  PALA   +  PA +    P    PSP  + PA  +        A ++    
Sbjct: 477 APTAAPALPPALA--ADQAPAPSPAPAPTVAEPSPPVSAPAPAA--------APIKTRTR 526

Query: 224 QLSRCRRLRGVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAAD 273
           +    R  RG  R        P    +  +P        GSG+++  AA+
Sbjct: 527 RNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAAN 576



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 53/206 (25%), Positives = 73/206 (35%), Gaps = 41/206 (19%)

Query: 180 EGC------PADTSVAFPPPPPPSPGAARPARFSFRLRPV-------FNASVQFLHCQLS 226
           EGC      PA  + A PPPP  +   ++P +F +   P        FN +   +     
Sbjct: 320 EGCSGPPSAPASQARALPPPPYTTFPGSKP-KFDWVSAPDGPERHFRFNGAGGGIGAPRR 378

Query: 227 RCRRLRGVRRAPAHLTPPPP-----------PLPSRCLPQDEACADTGSGSAEGLAADGP 275
           R   L G   +P    PPPP           P P+   P         +G  E +    P
Sbjct: 379 RAAALSGPWGSP----PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG--EPMRPGPP 432

Query: 276 HLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAP---AALEPAPVVALVLAAFVLG 332
            L  L        P PPP PP ++   A++P P   AP     L          AA  L 
Sbjct: 433 GLQELP-------PLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALP 485

Query: 333 AALAAGLGLVCAHSGTDDLRQAGPPV 358
            ALAA      + +    + +  PPV
Sbjct: 486 PALAADQAPAPSPAPAPTVAEPSPPV 511



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 58/221 (26%), Positives = 75/221 (33%), Gaps = 43/221 (19%)

Query: 65  QRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTED 124
           Q  R  RG  V FPG        +   P       P     P P +  P  +  +S    
Sbjct: 39  QAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPP- 97

Query: 125 VFPRRAGPLEVPADSRVFVQAALARPSPRWGL-ALHRCSVTPSS----RPAPGPALALLR 179
             P  AG L +P  S+    A    P  R  L A HR    P S    +P P P    ++
Sbjct: 98  --PAPAGTL-LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVK 154

Query: 180 EGCPADTSVAFPP-----PPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGV 234
           +  P   S   PP     PPPP P   +PA                        RR+   
Sbjct: 155 DTVPRAPSQFPPPLETWKPPPPLPSERQPAD-----------------------RRI--- 188

Query: 235 RRAPAHLTPPPPPLPSRCLPQDEA-CADTGSGSAEGLAADG 274
              PA  TP  PP  S+  P+++   A    G A   A +G
Sbjct: 189 --TPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEG 227


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,548,815
Number of Sequences: 37866
Number of extensions: 1560226
Number of successful extensions: 29196
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 377
Number of HSP's successfully gapped in prelim test: 1086
Number of HSP's that attempted gapping in prelim test: 14212
Number of HSP's gapped (non-prelim): 10638
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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