Search of human proteins with 21361331

Search of human proteins with 21361331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361331 carbamoyl-phosphate synthetase 1 isoform b
precursor [Homo sapiens]
         (1500 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso...  2981   0.0  
gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor...  2981   0.0  
gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa...  2081   0.0  
gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba...  1436   0.0  
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...    65   5e-10
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ...    65   5e-10
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ...    65   5e-10
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...    65   5e-10
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ...    65   5e-10
gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr...    62   3e-09
gi|106049528 pyruvate carboxylase precursor [Homo sapiens]             59   3e-08
gi|106049295 pyruvate carboxylase precursor [Homo sapiens]             59   3e-08
gi|106049292 pyruvate carboxylase precursor [Homo sapiens]             59   3e-08
gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ...    56   2e-07
gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide...    56   2e-07
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]         54   1e-06
gi|4504035 guanine monophosphate synthetase [Homo sapiens]             39   0.038
gi|28416899 phosphoribosylglycinamide formyltransferase, phospho...    38   0.084
gi|4503915 phosphoribosylglycinamide formyltransferase, phosphor...    38   0.084
gi|209869995 phosphoribosylglycinamide formyltransferase, phosph...    38   0.084
gi|209869993 phosphoribosylglycinamide formyltransferase, phosph...    38   0.084
gi|148839342 ATP-grasp domain containing 1 [Homo sapiens]              35   0.55 
gi|31377650 transmembrane protein 25 isoform 1 [Homo sapiens]          33   2.1  
gi|221139838 transmembrane protein 25 isoform 4 [Homo sapiens]         33   2.1  
gi|27436953 ATP-binding cassette, sub-family A, member 6 [Homo s...    33   2.7  
gi|30240932 EH-domain containing 1 [Homo sapiens]                      33   2.7  
gi|24308398 transmembrane protein 116 [Homo sapiens]                   32   4.6  

>gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor
            [Homo sapiens]
          Length = 1506

 Score = 2981 bits (7728), Expect = 0.0
 Identities = 1500/1500 (100%), Positives = 1500/1500 (100%)

Query: 1    MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYS 60
            MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYS
Sbjct: 7    MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYS 66

Query: 61   FGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKY 120
            FGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKY
Sbjct: 67   FGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKY 126

Query: 121  LESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML 180
            LESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
Sbjct: 127  LESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML 186

Query: 181  GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGA 240
            GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGA
Sbjct: 187  GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGA 246

Query: 241  EVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLIT 300
            EVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLIT
Sbjct: 247  EVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLIT 306

Query: 301  GLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQT 360
            GLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQT
Sbjct: 307  GLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQT 366

Query: 361  NEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRV 420
            NEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRV
Sbjct: 367  NEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRV 426

Query: 421  EVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQAD 480
            EVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQAD
Sbjct: 427  EVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQAD 486

Query: 481  TVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVES 540
            TVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVES
Sbjct: 487  TVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVES 546

Query: 541  IMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGIC 600
            IMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGIC
Sbjct: 547  IMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGIC 606

Query: 601  PNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHT 660
            PNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHT
Sbjct: 607  PNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHT 666

Query: 661  GDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLS 720
            GDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLS
Sbjct: 667  GDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLS 726

Query: 721  RSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDR 780
            RSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDR
Sbjct: 727  RSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDR 786

Query: 781  FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLR 840
            FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLR
Sbjct: 787  FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLR 846

Query: 841  KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT 900
            KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT
Sbjct: 847  KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT 906

Query: 901  EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV 960
            EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV
Sbjct: 907  EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV 966

Query: 961  TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV 1020
            TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV
Sbjct: 967  TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV 1026

Query: 1021 STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP 1080
            STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP
Sbjct: 1027 STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP 1086

Query: 1081 LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN 1140
            LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN
Sbjct: 1087 LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN 1146

Query: 1141 VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG 1200
            VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG
Sbjct: 1147 VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG 1206

Query: 1201 VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA 1260
            VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA
Sbjct: 1207 VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA 1266

Query: 1261 SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD 1320
            SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD
Sbjct: 1267 SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD 1326

Query: 1321 ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQ 1380
            ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQ
Sbjct: 1327 ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQ 1386

Query: 1381 LHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPN 1440
            LHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPN
Sbjct: 1387 LHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPN 1446

Query: 1441 NNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1500
            NNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
Sbjct: 1447 NNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1506


>gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor
            [Homo sapiens]
          Length = 1500

 Score = 2981 bits (7728), Expect = 0.0
 Identities = 1500/1500 (100%), Positives = 1500/1500 (100%)

Query: 1    MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYS 60
            MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYS
Sbjct: 1    MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYS 60

Query: 61   FGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKY 120
            FGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKY
Sbjct: 61   FGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKY 120

Query: 121  LESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML 180
            LESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
Sbjct: 121  LESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML 180

Query: 181  GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGA 240
            GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGA
Sbjct: 181  GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGA 240

Query: 241  EVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLIT 300
            EVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLIT
Sbjct: 241  EVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLIT 300

Query: 301  GLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQT 360
            GLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQT
Sbjct: 301  GLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQT 360

Query: 361  NEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRV 420
            NEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRV
Sbjct: 361  NEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRV 420

Query: 421  EVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQAD 480
            EVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQAD
Sbjct: 421  EVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQAD 480

Query: 481  TVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVES 540
            TVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVES
Sbjct: 481  TVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVES 540

Query: 541  IMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGIC 600
            IMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGIC
Sbjct: 541  IMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGIC 600

Query: 601  PNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHT 660
            PNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHT
Sbjct: 601  PNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHT 660

Query: 661  GDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLS 720
            GDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLS
Sbjct: 661  GDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLS 720

Query: 721  RSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDR 780
            RSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDR
Sbjct: 721  RSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDR 780

Query: 781  FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLR 840
            FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLR
Sbjct: 781  FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLR 840

Query: 841  KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT 900
            KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT
Sbjct: 841  KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT 900

Query: 901  EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV 960
            EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV
Sbjct: 901  EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV 960

Query: 961  TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV 1020
            TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV
Sbjct: 961  TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV 1020

Query: 1021 STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP 1080
            STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP
Sbjct: 1021 STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP 1080

Query: 1081 LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN 1140
            LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN
Sbjct: 1081 LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN 1140

Query: 1141 VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG 1200
            VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG
Sbjct: 1141 VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG 1200

Query: 1201 VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA 1260
            VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA
Sbjct: 1201 VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA 1260

Query: 1261 SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD 1320
            SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD
Sbjct: 1261 SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD 1320

Query: 1321 ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQ 1380
            ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQ
Sbjct: 1321 ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQ 1380

Query: 1381 LHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPN 1440
            LHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPN
Sbjct: 1381 LHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPN 1440

Query: 1441 NNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1500
            NNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
Sbjct: 1441 NNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1500


>gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo
            sapiens]
          Length = 1049

 Score = 2081 bits (5392), Expect = 0.0
 Identities = 1049/1049 (100%), Positives = 1049/1049 (100%)

Query: 452  MKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQ 511
            MKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQ
Sbjct: 1    MKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQ 60

Query: 512  TALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIE 571
            TALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIE
Sbjct: 61   TALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIE 120

Query: 572  DALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKE 631
            DALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKE
Sbjct: 121  DALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKE 180

Query: 632  IEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHL 691
            IEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHL
Sbjct: 181  IEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHL 240

Query: 692  GIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIK 751
            GIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIK
Sbjct: 241  GIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIK 300

Query: 752  NVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQK 811
            NVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQK
Sbjct: 301  NVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQK 360

Query: 812  ALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLT 871
            ALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLT
Sbjct: 361  ALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLT 420

Query: 872  YIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTREL 931
            YIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTREL
Sbjct: 421  YIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTREL 480

Query: 932  RLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVE 991
            RLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVE
Sbjct: 481  RLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVE 540

Query: 992  FDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGG 1051
            FDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGG
Sbjct: 541  FDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGG 600

Query: 1052 CIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNT 1111
            CIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNT
Sbjct: 601  CIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNT 660

Query: 1112 LNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVE 1171
            LNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVE
Sbjct: 661  LNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVE 720

Query: 1172 GAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIA 1231
            GAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIA
Sbjct: 721  GAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIA 780

Query: 1232 KAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEK 1291
            KAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEK
Sbjct: 781  KAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEK 840

Query: 1292 HLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAML 1351
            HLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAML
Sbjct: 841  HLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAML 900

Query: 1352 STGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWP 1411
            STGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWP
Sbjct: 901  STGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWP 960

Query: 1412 SQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTK 1471
            SQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTK
Sbjct: 961  SQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTK 1020

Query: 1472 LFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1500
            LFAEAVQKSRKVDSKSLFHYRQYSAGKAA
Sbjct: 1021 LFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1049



 Score =  167 bits (422), Expect = 9e-41
 Identities = 109/393 (27%), Positives = 192/393 (48%), Gaps = 22/393 (5%)

Query: 425 VLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYF 484
           +++LG G   IG + EFD+    +++ +++   KTV++N N  +V T+     + D +YF
Sbjct: 525 MMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTD---FDECDKLYF 581

Query: 485 LPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMAT 544
             ++ + + ++   E   G I+ +GGQ   N  V L+K       GVK++GTS   I   
Sbjct: 582 EELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKN------GVKIMGTSPLQIDRA 635

Query: 545 EDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRE 604
           EDR +FS  L+E+    AP  AV ++ +AL+ A ++ YP ++R +Y L G    +  + +
Sbjct: 636 EDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSED 695

Query: 605 TLMDLSTKAFAMTNQ--ILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGD 662
            +     +A  ++ +  +++ K V G +E+E + V   D   ++    E+V+  GVH+GD
Sbjct: 696 EMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAV-GKDGRVISHAISEHVEDAGVHSGD 754

Query: 663 SVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRS 722
           + ++ P QT+S    + ++  +  + +   I G  N+QF +     +  +IE N R SRS
Sbjct: 755 ATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLV--KGNDVLVIECNLRASRS 812

Query: 723 SALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSL--DYMVTKIPRWDLDR 780
               SK  G     +A K+ +G      +NV          P +  DY+  K P +   R
Sbjct: 813 FPFVSKTLGVDFIDVATKVMIG------ENVDEKHLPTLDHPIIPADYVAIKAPMFSWPR 866

Query: 781 FHGTSSRIGSSMKSVGEVMAIGRTFEESFQKAL 813
                  +   M S GEV   G     +F KA+
Sbjct: 867 LRDADPILRCEMASTGEVACFGEGIHTAFLKAM 899


>gi|18105007 carbamoylphosphate synthetase 2/aspartate
            transcarbamylase/dihydroorotase [Homo sapiens]
          Length = 2225

 Score = 1436 bits (3717), Expect = 0.0
 Identities = 747/1458 (51%), Positives = 1018/1458 (69%), Gaps = 45/1458 (3%)

Query: 46   AHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGG 105
            A +VLEDG+ ++G  FG   S AGEVVF TG+ GYPEA+TDP+YK QIL +  P+IGN G
Sbjct: 2    AALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYG 61

Query: 106  APDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVD 165
             P    +DE GL K+ ES+GI V+ L+V +     +HW AT++L +WLQ+  +P + GVD
Sbjct: 62   IPPDE-MDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD 120

Query: 166  TRMLTKIIRDKGTMLGKIEFEG---QPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVA 222
            TR LTK +R++G++LGK+   G     + F+DPN + L+ EVS K  +V+  G   +++A
Sbjct: 121  TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA 180

Query: 223  VDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKIL 282
            +DCG+K N IR L +RGAEV +VPW+H     EY+G+ ++ GPG+PA    ++  + ++L
Sbjct: 181  LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL 240

Query: 283  ESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALD 342
                  P+FGI  G+ +  LA GAKTYKM   NRG NQP L + + + F+T+QNHG+A++
Sbjct: 241  SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE 300

Query: 343  -NTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKG 401
             ++LPA W PLF N ND +NEGI+H S PFF+VQFHPE   GP D E LFD F   +K+ 
Sbjct: 301  TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA 360

Query: 402  KATT---------ITSVLPKPALVASRVEVS---KVLILGSGGLSIGQAGEFDYSGSQAV 449
             A           +T  L  P +      +    KVLILGSGGLSIGQAGEFDYSGSQA+
Sbjct: 361  TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI 420

Query: 450  KAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMG 509
            KA+KEEN++T+L+NPNIA+VQT++ GL  AD VYFLPITP +VT+VI+ E+PDG++L  G
Sbjct: 421  KALKEENIQTLLINPNIATVQTSQ-GL--ADKVYFLPITPHYVTQVIRNERPDGVLLTFG 477

Query: 510  GQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVES 569
            GQTALNCGVEL K GVL  YGV+VLGT VE+I  TEDR+ F+ ++ EI E +APS A  S
Sbjct: 478  GQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANS 537

Query: 570  IEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGW 629
            +E A  AA+ +GYPV++R+A+ALGGLGSG   NRE L  L   AFA T+Q+LV+KS+ GW
Sbjct: 538  LEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGW 597

Query: 630  KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVR 689
            KEIEYEVVRDA  NCVTVCNMEN+D +G+HTG+S+VVAP+QTL++ E+Q+LR+T+I V +
Sbjct: 598  KEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQ 657

Query: 690  HLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPE 749
            HLGIVGECN+Q+AL+P S +Y IIEVNARLSRSSALASKATGYPLA++AAK+ALGIPLPE
Sbjct: 658  HLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPE 717

Query: 750  IKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESF 809
            ++N V+G T+A FEPS+DY V KIPRWDL +F   S++IGS MKSVGEVM IGR+FEE+F
Sbjct: 718  LRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAF 776

Query: 810  QKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEK 869
            QKALRM   +  GF   +    +         EL  P+  RI+ +A A+    S+D + +
Sbjct: 777  QKALRMVDENCVGFDHTVKPVSDM--------ELETPTDKRIFVVAAALWAGYSVDRLYE 828

Query: 870  LTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTR 929
            LT ID+WFL++M+ I+   + L+    + +  + L++AK +GFSDKQI+  +  TE   R
Sbjct: 829  LTRIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVR 888

Query: 930  ELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSS 989
            +LR +  I P VKQIDT+AAE+P+ TNYLY+TY G  HD+ F    ++VLG G Y IGSS
Sbjct: 889  KLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSS 948

Query: 990  VEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEAC 1049
            VEFDWCAV  I+ LR++G KT++VN NPETVSTD+D CD+LYF+E+S E ++DIY  E  
Sbjct: 949  VEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENP 1008

Query: 1050 GGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAV 1109
             G I+S+GGQ+PNN+A+ L++   +++GTSP  ID AE+R  FS +LD + ++Q  W+ +
Sbjct: 1009 EGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWREL 1068

Query: 1110 NTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKF 1169
            + L  A +F ++V YPC++RPSYVLSG+AMNV +++ ++++FL  A  VS+EHPVV++KF
Sbjct: 1069 SDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKF 1128

Query: 1170 VEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRK 1229
            ++ A+E+++DAV  DG V + AISEHVE+AGVHSGDATL+ P Q I+   +E++K     
Sbjct: 1129 IQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHA 1188

Query: 1230 IAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVD 1289
            + +   ++GPFN+Q + K + + VIECN+R SRSFPFVSKTLGVD + +AT+V++GE V+
Sbjct: 1189 VGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVE 1248

Query: 1290 EKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKA 1349
               L T       +  V +K P FS+ RL  AD +L  EM STGEVA FGE    A+LKA
Sbjct: 1249 PVGLMT------GSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKA 1302

Query: 1350 MLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPV 1408
            MLSTGFKIP+K IL+ I     +   L     L + G+ L+A+  T+D+   + V  T V
Sbjct: 1303 MLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAV 1362

Query: 1409 AWPSQE---GQNPSLSSIRKLIRDGSIDLVINLPNNN------TKFVHDNYVIRRTAVDS 1459
             W  +E   G+ P   SI + + + + +LVINL          + FV   Y  RR A D 
Sbjct: 1363 DWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADF 1422

Query: 1460 GIPLLTNFQVTKLFAEAV 1477
             +PL+ + + TKLF EA+
Sbjct: 1423 SVPLIIDIKCTKLFVEAL 1440


>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
           sapiens]
          Length = 2346

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 9/252 (3%)

Query: 506 LGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF 565
           +G   Q     G ++    V +  G+  L  S   +        FS ++  + +++    
Sbjct: 230 MGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKG 289

Query: 566 AVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDL--STKAFAMTNQILVE 623
            V+ ++D L+AA+ +GYPVMI+++   GG G     N +   +L    +A    + I V 
Sbjct: 290 YVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVM 349

Query: 624 KSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--APAQTLSNAEFQMLR 681
           +     + +E +++ D   N +++   +      V      ++  APA   + A F+ + 
Sbjct: 350 RLAKQSRHLEVQILADQYGNAISLFGRD----CSVQRRHQKIIEEAPATIATPAVFEHME 405

Query: 682 RTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKI 741
           + ++ + + +G V    +++ L+     +  +E+N RL              L     +I
Sbjct: 406 QCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQI 464

Query: 742 ALGIPLPEIKNV 753
           A+GIPL  IK++
Sbjct: 465 AMGIPLYRIKDI 476


>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
           sapiens]
          Length = 2268

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 9/252 (3%)

Query: 506 LGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF 565
           +G   Q     G ++    V +  G+  L  S   +        FS ++  + +++    
Sbjct: 152 MGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKG 211

Query: 566 AVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDL--STKAFAMTNQILVE 623
            V+ ++D L+AA+ +GYPVMI+++   GG G     N +   +L    +A    + I V 
Sbjct: 212 YVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVM 271

Query: 624 KSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--APAQTLSNAEFQMLR 681
           +     + +E +++ D   N +++   +      V      ++  APA   + A F+ + 
Sbjct: 272 RLAKQSRHLEVQILADQYGNAISLFGRD----CSVQRRHQKIIEEAPATIATPAVFEHME 327

Query: 682 RTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKI 741
           + ++ + + +G V    +++ L+     +  +E+N RL              L     +I
Sbjct: 328 QCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQI 386

Query: 742 ALGIPLPEIKNV 753
           A+GIPL  IK++
Sbjct: 387 AMGIPLYRIKDI 398


>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
           sapiens]
          Length = 2288

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 9/252 (3%)

Query: 506 LGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF 565
           +G   Q     G ++    V +  G+  L  S   +        FS ++  + +++    
Sbjct: 172 MGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKG 231

Query: 566 AVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDL--STKAFAMTNQILVE 623
            V+ ++D L+AA+ +GYPVMI+++   GG G     N +   +L    +A    + I V 
Sbjct: 232 YVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVM 291

Query: 624 KSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--APAQTLSNAEFQMLR 681
           +     + +E +++ D   N +++   +      V      ++  APA   + A F+ + 
Sbjct: 292 RLAKQSRHLEVQILADQYGNAISLFGRD----CSVQRRHQKIIEEAPATIATPAVFEHME 347

Query: 682 RTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKI 741
           + ++ + + +G V    +++ L+     +  +E+N RL              L     +I
Sbjct: 348 QCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQI 406

Query: 742 ALGIPLPEIKNV 753
           A+GIPL  IK++
Sbjct: 407 AMGIPLYRIKDI 418


>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
           sapiens]
          Length = 2346

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 9/252 (3%)

Query: 506 LGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF 565
           +G   Q     G ++    V +  G+  L  S   +        FS ++  + +++    
Sbjct: 230 MGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKG 289

Query: 566 AVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDL--STKAFAMTNQILVE 623
            V+ ++D L+AA+ +GYPVMI+++   GG G     N +   +L    +A    + I V 
Sbjct: 290 YVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVM 349

Query: 624 KSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--APAQTLSNAEFQMLR 681
           +     + +E +++ D   N +++   +      V      ++  APA   + A F+ + 
Sbjct: 350 RLAKQSRHLEVQILADQYGNAISLFGRD----CSVQRRHQKIIEEAPATIATPAVFEHME 405

Query: 682 RTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKI 741
           + ++ + + +G V    +++ L+     +  +E+N RL              L     +I
Sbjct: 406 QCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQI 464

Query: 742 ALGIPLPEIKNV 753
           A+GIPL  IK++
Sbjct: 465 AMGIPLYRIKDI 476


>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
           sapiens]
          Length = 2383

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 9/252 (3%)

Query: 506 LGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF 565
           +G   Q     G ++    V +  G+  L  S   +        FS ++  + +++    
Sbjct: 267 MGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKG 326

Query: 566 AVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDL--STKAFAMTNQILVE 623
            V+ ++D L+AA+ +GYPVMI+++   GG G     N +   +L    +A    + I V 
Sbjct: 327 YVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVM 386

Query: 624 KSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--APAQTLSNAEFQMLR 681
           +     + +E +++ D   N +++   +      V      ++  APA   + A F+ + 
Sbjct: 387 RLAKQSRHLEVQILADQYGNAISLFGRD----CSVQRRHQKIIEEAPATIATPAVFEHME 442

Query: 682 RTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKI 741
           + ++ + + +G V    +++ L+     +  +E+N RL              L     +I
Sbjct: 443 QCAVKLAKMVGYVSAGTVEY-LYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQI 501

Query: 742 ALGIPLPEIKNV 753
           A+GIPL  IK++
Sbjct: 502 AMGIPLYRIKDI 513


>gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
            precursor [Homo sapiens]
          Length = 725

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 72/310 (23%), Positives = 124/310 (40%), Gaps = 27/310 (8%)

Query: 1000 IRTLRQLGKKTVVVNCNPETVSTDFDECDKLYF--------EELSLERILDIYHQEACGG 1051
            +RT ++LG +TV V    +  S   D  D+ Y           LS+E+I+ +    A   
Sbjct: 65   MRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQA 124

Query: 1052 CIISVGGQIPNNLAVPLYK-NGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAP----W 1106
                 G    N     L K  G+  +G  P  I    D  I S     +  A  P    +
Sbjct: 125  IHPGCGFLSENMEFAELCKQEGIIFIGPPPSAI---RDMGIKSTSKSIMAAAGVPVVEGY 181

Query: 1107 KAVNTLNEAL-EFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQ----E 1161
               +  ++ L E A+ + YP +++      G  M +V SE E ++ LE A R ++    +
Sbjct: 182  HGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFND 241

Query: 1162 HPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLM--LPTQTISQGA 1219
              +++ KFV+  R VE+   G       +A+     D  V      ++   P   I    
Sbjct: 242  DAMLIEKFVDTPRHVEVQVFGDHH---GNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEV 298

Query: 1220 IEKVKDATRKIAKAFAISGPFNVQFLVKG-NDVLVIECNLRASRSFPFVSKTLGVDFIDV 1278
             +K+ +A  + AKA    G   V+F++   ++   +E N R     P      G D ++ 
Sbjct: 299  RKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEW 358

Query: 1279 ATKVMIGENV 1288
              ++  GE +
Sbjct: 359  QLRIAAGEKI 368



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 42/178 (23%), Positives = 74/178 (41%), Gaps = 9/178 (5%)

Query: 577 ADTIGYPVMIRSAYALGGLGSGICPNRETLMD------LSTKAFAMTNQILVEKSVTGWK 630
           A  IGYPVMI++    GG G  I  + +   +         K     + +L+EK V   +
Sbjct: 195 ARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPR 254

Query: 631 EIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRH 690
            +E +V  D   N V +   E   ++       +  APA  + +   + L   ++   + 
Sbjct: 255 HVEVQVFGDHHGNAVYL--FERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKA 312

Query: 691 LGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748
           +  VG   ++F +  +   +C +E+N RL     +    TG  L     +IA G  +P
Sbjct: 313 VNYVGAGTVEFIM-DSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIP 369


>gi|106049528 pyruvate carboxylase precursor [Homo sapiens]
          Length = 1178

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)

Query: 407 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 463
           TS  P  +    R+E   + KV++   G ++I           +  +A  E  ++TV + 
Sbjct: 19  TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66

Query: 464 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 517
              +   T ++  ++AD  Y +     P+     + ++IK  + + +     G   L+  
Sbjct: 67  --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124

Query: 518 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 575
            +  +    ++ GV+ +G S E +    D+             + P     + S+ +A +
Sbjct: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182

Query: 576 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 629
            ++T G+P++ ++AY  GG G  +  + E L +  T+A++          + VEK +   
Sbjct: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242

Query: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 688
           + IE +++ D   N   + ++   D         VV +APA  L       L   S+ + 
Sbjct: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299

Query: 689 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748
           + +G      ++F +      Y  IEVN+RL     +  + T   L      +A G  LP
Sbjct: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358

Query: 749 EI 750
           ++
Sbjct: 359 DL 360


>gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
          Length = 1178

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)

Query: 407 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 463
           TS  P  +    R+E   + KV++   G ++I           +  +A  E  ++TV + 
Sbjct: 19  TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66

Query: 464 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 517
              +   T ++  ++AD  Y +     P+     + ++IK  + + +     G   L+  
Sbjct: 67  --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124

Query: 518 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 575
            +  +    ++ GV+ +G S E +    D+             + P     + S+ +A +
Sbjct: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182

Query: 576 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 629
            ++T G+P++ ++AY  GG G  +  + E L +  T+A++          + VEK +   
Sbjct: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242

Query: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 688
           + IE +++ D   N   + ++   D         VV +APA  L       L   S+ + 
Sbjct: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299

Query: 689 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748
           + +G      ++F +      Y  IEVN+RL     +  + T   L      +A G  LP
Sbjct: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358

Query: 749 EI 750
           ++
Sbjct: 359 DL 360


>gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
          Length = 1178

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)

Query: 407 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 463
           TS  P  +    R+E   + KV++   G ++I           +  +A  E  ++TV + 
Sbjct: 19  TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66

Query: 464 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 517
              +   T ++  ++AD  Y +     P+     + ++IK  + + +     G   L+  
Sbjct: 67  --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124

Query: 518 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 575
            +  +    ++ GV+ +G S E +    D+             + P     + S+ +A +
Sbjct: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182

Query: 576 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 629
            ++T G+P++ ++AY  GG G  +  + E L +  T+A++          + VEK +   
Sbjct: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242

Query: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 688
           + IE +++ D   N   + ++   D         VV +APA  L       L   S+ + 
Sbjct: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299

Query: 689 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748
           + +G      ++F +      Y  IEVN+RL     +  + T   L      +A G  LP
Sbjct: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358

Query: 749 EI 750
           ++
Sbjct: 359 DL 360


>gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide
           isoform a precursor [Homo sapiens]
          Length = 728

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 77/320 (24%), Positives = 138/320 (43%), Gaps = 33/320 (10%)

Query: 447 QAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITP--------QFVTEVIKA 498
           + ++  K+  +KTV ++   + V  + V +K AD    +   P          + E IK 
Sbjct: 77  RVIRTCKKMGIKTVAIH---SDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKK 133

Query: 499 EQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDR---QLFSDKLN 555
            +   +  G G    L+   E F R +  E  V  +G    +I A  D+   +L + K  
Sbjct: 134 TRAQAVHPGYG---FLSENKE-FARCLAAE-DVVFIGPDTHAIQAMGDKIESKLLAKKA- 187

Query: 556 EINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMD---LSTK 612
           E+N        V+  E+A++ A  IGYPVMI+++   GG G  I  + E   D   LS++
Sbjct: 188 EVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQ 247

Query: 613 AFAMT---NQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--A 667
             A +   +++L+EK +   + IE +V+ D   N + +    N     +   +  VV  A
Sbjct: 248 EAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWL----NERECSIQRRNQKVVEEA 303

Query: 668 PAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALAS 727
           P+  L     + +   ++ + R +       ++F L  +   +  +E+N RL     +  
Sbjct: 304 PSIFLDAETRRAMGEQAVALARAVKYSSAGTVEF-LVDSKKNFYFLEMNTRLQVEHPVTE 362

Query: 728 KATGYPLAFIAAKIALGIPL 747
             TG  L     ++A G PL
Sbjct: 363 CITGLDLVQEMIRVAKGYPL 382



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 60/311 (19%), Positives = 117/311 (37%), Gaps = 35/311 (11%)

Query: 1000 IRTLRQLGKKTVVVNCNPETVSTDFDECDKLYF--------EELSLERILDIYHQEACGG 1051
            IRT +++G KTV ++ + +  S      D+             L+++ I++   +     
Sbjct: 79   IRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQA 138

Query: 1052 CIISVGGQIPNN-LAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPW--KA 1108
                 G    N   A  L    V  +G     I    D+     +  + +V   P     
Sbjct: 139  VHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGV 198

Query: 1109 VNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFL----EEATRVSQEHPV 1164
            V    EA+  A+ + YP +++ S    G  M + + ++E +       +EA     +  +
Sbjct: 199  VKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRL 258

Query: 1165 VLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVK 1224
            ++ KF++  R +E+  +G           +H     ++  + ++    Q + + A     
Sbjct: 259  LIEKFIDNPRHIEIQVLG----------DKHGNALWLNERECSIQRRNQKVVEEAPSIFL 308

Query: 1225 DA-TRK--------IAKAFAISGPFNVQFLVKG-NDVLVIECNLRASRSFPFVSKTLGVD 1274
            DA TR+        +A+A   S    V+FLV    +   +E N R     P      G+D
Sbjct: 309  DAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLD 368

Query: 1275 FIDVATKVMIG 1285
             +    +V  G
Sbjct: 369  LVQEMIRVAKG 379


>gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide
           isoform b [Homo sapiens]
          Length = 702

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 77/320 (24%), Positives = 138/320 (43%), Gaps = 33/320 (10%)

Query: 447 QAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITP--------QFVTEVIKA 498
           + ++  K+  +KTV ++   + V  + V +K AD    +   P          + E IK 
Sbjct: 51  RVIRTCKKMGIKTVAIH---SDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKK 107

Query: 499 EQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDR---QLFSDKLN 555
            +   +  G G    L+   E F R +  E  V  +G    +I A  D+   +L + K  
Sbjct: 108 TRAQAVHPGYG---FLSENKE-FARCLAAE-DVVFIGPDTHAIQAMGDKIESKLLAKKA- 161

Query: 556 EINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMD---LSTK 612
           E+N        V+  E+A++ A  IGYPVMI+++   GG G  I  + E   D   LS++
Sbjct: 162 EVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQ 221

Query: 613 AFAMT---NQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV--A 667
             A +   +++L+EK +   + IE +V+ D   N + +    N     +   +  VV  A
Sbjct: 222 EAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWL----NERECSIQRRNQKVVEEA 277

Query: 668 PAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALAS 727
           P+  L     + +   ++ + R +       ++F L  +   +  +E+N RL     +  
Sbjct: 278 PSIFLDAETRRAMGEQAVALARAVKYSSAGTVEF-LVDSKKNFYFLEMNTRLQVEHPVTE 336

Query: 728 KATGYPLAFIAAKIALGIPL 747
             TG  L     ++A G PL
Sbjct: 337 CITGLDLVQEMIRVAKGYPL 356



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 60/311 (19%), Positives = 117/311 (37%), Gaps = 35/311 (11%)

Query: 1000 IRTLRQLGKKTVVVNCNPETVSTDFDECDKLYF--------EELSLERILDIYHQEACGG 1051
            IRT +++G KTV ++ + +  S      D+             L+++ I++   +     
Sbjct: 53   IRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQA 112

Query: 1052 CIISVGGQIPNN-LAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPW--KA 1108
                 G    N   A  L    V  +G     I    D+     +  + +V   P     
Sbjct: 113  VHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGV 172

Query: 1109 VNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFL----EEATRVSQEHPV 1164
            V    EA+  A+ + YP +++ S    G  M + + ++E +       +EA     +  +
Sbjct: 173  VKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRL 232

Query: 1165 VLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVK 1224
            ++ KF++  R +E+  +G           +H     ++  + ++    Q + + A     
Sbjct: 233  LIEKFIDNPRHIEIQVLG----------DKHGNALWLNERECSIQRRNQKVVEEAPSIFL 282

Query: 1225 DA-TRK--------IAKAFAISGPFNVQFLVKG-NDVLVIECNLRASRSFPFVSKTLGVD 1274
            DA TR+        +A+A   S    V+FLV    +   +E N R     P      G+D
Sbjct: 283  DAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLD 342

Query: 1275 FIDVATKVMIG 1285
             +    +V  G
Sbjct: 343  LVQEMIRVAKG 353


>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
          Length = 2458

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 47/216 (21%), Positives = 97/216 (44%), Gaps = 14/216 (6%)

Query: 544 TEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNR 603
           TED  L   K   + E +     V+ +++ L+AA+ IG+P+MI+++   GG G     + 
Sbjct: 412 TED-DLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESA 470

Query: 604 E--TLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTV----CNMENVDAMG 657
           E   ++    ++    + I + K     + +E +++ D   N V++    C+++      
Sbjct: 471 EDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQR----- 525

Query: 658 VHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNA 717
                 V  APA     A F+ + + +I + + +G V    +++ L+     +  +E+N 
Sbjct: 526 -RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEY-LYSQDGSFHFLELNP 583

Query: 718 RLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNV 753
           RL              L     +IA+G+PL  +K++
Sbjct: 584 RLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDI 619


>gi|4504035 guanine monophosphate synthetase [Homo sapiens]
          Length = 693

 Score = 38.9 bits (89), Expect = 0.038
 Identities = 53/191 (27%), Positives = 78/191 (40%), Gaps = 25/191 (13%)

Query: 256 YDGILIAGGPGNPALAE------PLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTY 309
           +  I+I+GGP N   AE      P I  + K        P+ GI  G  +     G   +
Sbjct: 69  FRAIIISGGP-NSVYAEDAPWFDPAIFTIGK--------PVLGICYGMQMMNKVFGGTVH 119

Query: 310 KMSMANRGQ-NQPVLNITN-----KQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEG 363
           K S+   G  N  V N  +     ++  +    HG ++D     G+K +  + N     G
Sbjct: 120 KKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVAD-GFKVVARSGNIVA--G 176

Query: 364 IMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIK-KGKATTITSVLPKPALVASRVEV 422
           I +ESK  +  QFHPEV         L +  + +    G  T     L     +  RV  
Sbjct: 177 IANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGT 236

Query: 423 SKVLILGSGGL 433
           SKVL+L SGG+
Sbjct: 237 SKVLVLLSGGV 247


>gi|28416899 phosphoribosylglycinamide formyltransferase,
            phosphoribosylglycinamide synthetase,
            phosphoribosylaminoimidazole synthetase isoform 2 [Homo
            sapiens]
          Length = 433

 Score = 37.7 bits (86), Expect = 0.084
 Identities = 35/165 (21%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 1072 GVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCL-LRP 1130
            GV+  G +         +      +D   +  A WKA     EA  F  S D+P L ++ 
Sbjct: 90   GVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKA 149

Query: 1131 SYVLSGSAMNVVFSEDE----MKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGR 1186
            S + +G  + V  S++E    +++ ++E    +    +V+ + ++G  E        DG+
Sbjct: 150  SGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDG--EEVSCLCFTDGK 207

Query: 1187 VIS--HAISEHVE----DAGVHSGDATLMLPTQTISQGAIEKVKD 1225
             ++      +H      D G ++G      P   +S   + K+KD
Sbjct: 208  TVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKD 252


>gi|4503915 phosphoribosylglycinamide formyltransferase,
            phosphoribosylglycinamide synthetase,
            phosphoribosylaminoimidazole synthetase isoform 1 [Homo
            sapiens]
          Length = 1010

 Score = 37.7 bits (86), Expect = 0.084
 Identities = 35/165 (21%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 1072 GVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCL-LRP 1130
            GV+  G +         +      +D   +  A WKA     EA  F  S D+P L ++ 
Sbjct: 90   GVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKA 149

Query: 1131 SYVLSGSAMNVVFSEDE----MKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGR 1186
            S + +G  + V  S++E    +++ ++E    +    +V+ + ++G  E        DG+
Sbjct: 150  SGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDG--EEVSCLCFTDGK 207

Query: 1187 VIS--HAISEHVE----DAGVHSGDATLMLPTQTISQGAIEKVKD 1225
             ++      +H      D G ++G      P   +S   + K+KD
Sbjct: 208  TVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKD 252


>gi|209869995 phosphoribosylglycinamide formyltransferase,
            phosphoribosylglycinamide synthetase,
            phosphoribosylaminoimidazole synthetase isoform 1 [Homo
            sapiens]
          Length = 1010

 Score = 37.7 bits (86), Expect = 0.084
 Identities = 35/165 (21%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 1072 GVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCL-LRP 1130
            GV+  G +         +      +D   +  A WKA     EA  F  S D+P L ++ 
Sbjct: 90   GVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKA 149

Query: 1131 SYVLSGSAMNVVFSEDE----MKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGR 1186
            S + +G  + V  S++E    +++ ++E    +    +V+ + ++G  E        DG+
Sbjct: 150  SGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDG--EEVSCLCFTDGK 207

Query: 1187 VIS--HAISEHVE----DAGVHSGDATLMLPTQTISQGAIEKVKD 1225
             ++      +H      D G ++G      P   +S   + K+KD
Sbjct: 208  TVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKD 252


>gi|209869993 phosphoribosylglycinamide formyltransferase,
            phosphoribosylglycinamide synthetase,
            phosphoribosylaminoimidazole synthetase isoform 1 [Homo
            sapiens]
          Length = 1010

 Score = 37.7 bits (86), Expect = 0.084
 Identities = 35/165 (21%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 1072 GVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCL-LRP 1130
            GV+  G +         +      +D   +  A WKA     EA  F  S D+P L ++ 
Sbjct: 90   GVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKA 149

Query: 1131 SYVLSGSAMNVVFSEDE----MKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGR 1186
            S + +G  + V  S++E    +++ ++E    +    +V+ + ++G  E        DG+
Sbjct: 150  SGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDG--EEVSCLCFTDGK 207

Query: 1187 VIS--HAISEHVE----DAGVHSGDATLMLPTQTISQGAIEKVKD 1225
             ++      +H      D G ++G      P   +S   + K+KD
Sbjct: 208  TVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKD 252


>gi|148839342 ATP-grasp domain containing 1 [Homo sapiens]
          Length = 827

 Score = 35.0 bits (79), Expect = 0.55
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 3/124 (2%)

Query: 1164 VVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKV 1223
            ++L +FVEG  E ++D V   GR+++  +S++         +    +PT    +   + V
Sbjct: 599  MLLMEFVEGT-EHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMV 657

Query: 1224 KDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSF--PFVSKTLGVDFIDVATK 1281
            + A R       + G FNV+  + G    +IE N R    +   ++ +  GVD +  A  
Sbjct: 658  QAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVM 717

Query: 1282 VMIG 1285
            V  G
Sbjct: 718  VACG 721


>gi|31377650 transmembrane protein 25 isoform 1 [Homo sapiens]
          Length = 366

 Score = 33.1 bits (74), Expect = 2.1
 Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%)

Query: 396 SLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEE 455
           S++        ++ LP P L+A+RVEV  + I+ + GL++G    F    +  V   KE+
Sbjct: 207 SVVATNDVGVTSASLPAPGLLATRVEVPLLGIVVAAGLALGTLVGFSTLVACLV-CRKEK 265

Query: 456 NVKTVLMNPNIASVQTNEVGL 476
             K    +P++ S  +N + L
Sbjct: 266 KTKGPSRHPSLISSDSNNLKL 286


>gi|221139838 transmembrane protein 25 isoform 4 [Homo sapiens]
          Length = 351

 Score = 33.1 bits (74), Expect = 2.1
 Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%)

Query: 396 SLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEE 455
           S++        ++ LP P L+A+RVEV  + I+ + GL++G    F    +  V   KE+
Sbjct: 207 SVVATNDVGVTSASLPAPGLLATRVEVPLLGIVVAAGLALGTLVGFSTLVACLV-CRKEK 265

Query: 456 NVKTVLMNPNIASVQTNEVGL 476
             K    +P++ S  +N + L
Sbjct: 266 KTKGPSRHPSLISSDSNNLKL 286


>gi|27436953 ATP-binding cassette, sub-family A, member 6 [Homo
           sapiens]
          Length = 1617

 Score = 32.7 bits (73), Expect = 2.7
 Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 835 SNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWF-----LYKMRDILNMEK 889
           S L++   LS P+   +    K + +   L+EI K+T +   F     +  +++ L++  
Sbjct: 522 SLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFA 581

Query: 890 TLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTREL 931
            +KG++ + + +E  +   E+   + Q +    L+E Q R+L
Sbjct: 582 KIKGIHLKEVEQEVQRILLELDMQNIQDNLAKHLSEGQKRKL 623


>gi|30240932 EH-domain containing 1 [Homo sapiens]
          Length = 534

 Score = 32.7 bits (73), Expect = 2.7
 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 5/94 (5%)

Query: 155 EEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQ--PVDFVDPNKQNLIAEVSTKDVKVY 212
           ++++P ++G +++   +++ + G +  KIE E Q  P DF  P+ + +   + T+D   +
Sbjct: 315 KKEMPNVFGKESKK-KELVNNLGEIYQKIEREHQISPGDF--PSLRKMQELLQTQDFSKF 371

Query: 213 GKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVP 246
               P  +  VD  + N++ RL+V    E  L+P
Sbjct: 372 QALKPKLLDTVDDMLANDIARLMVMVRQEESLMP 405


>gi|24308398 transmembrane protein 116 [Homo sapiens]
          Length = 245

 Score = 32.0 bits (71), Expect = 4.6
 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 612 KAFAMTNQILVEKSVTGWKE-----IEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVV 666
           +A   T+Q L+   V GW +     ++ E  RDAD     +C+ +   + G+++ +S + 
Sbjct: 177 QALTATSQGLLNCGVYGWTQHKFHQLKQEARRDADTQTPLLCSQKRFYSRGLNSLESTLT 236

Query: 667 APAQT 671
            PA T
Sbjct: 237 FPAST 241


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,143,549
Number of Sequences: 37866
Number of extensions: 2268223
Number of successful extensions: 5132
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5018
Number of HSP's gapped (non-prelim): 56
length of query: 1500
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1385
effective length of database: 13,892,928
effective search space: 19241705280
effective search space used: 19241705280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.