Guide to the Human Genome
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Search of human proteins with 21264578

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21264578 tetraspan 1 [Homo sapiens]
         (241 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21264578 tetraspan 1 [Homo sapiens]                                489   e-138
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                   138   5e-33
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                   127   1e-29
gi|5729941 tetraspanin 9 [Homo sapiens]                               115   3e-26
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                    112   3e-25
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                     112   3e-25
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                    112   3e-25
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                    112   3e-25
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                    112   3e-25
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                    112   3e-25
gi|122937466 tetraspanin 11 [Homo sapiens]                            107   9e-24
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      106   2e-23
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]        105   3e-23
gi|21265104 tetraspanin 7 [Homo sapiens]                              105   4e-23
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        102   2e-22
gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]       102   4e-22
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...   100   9e-22
gi|10834972 CD53 antigen [Homo sapiens]                               100   1e-21
gi|91106727 CD53 antigen [Homo sapiens]                               100   1e-21
gi|4502663 CD37 antigen isoform A [Homo sapiens]                       95   5e-20
gi|21264580 tetraspan 2 [Homo sapiens]                                 92   5e-19
gi|87159824 CD151 antigen [Homo sapiens]                               91   1e-18
gi|87159822 CD151 antigen [Homo sapiens]                               91   1e-18
gi|21237751 CD151 antigen [Homo sapiens]                               91   1e-18
gi|21237748 CD151 antigen [Homo sapiens]                               91   1e-18
gi|4502679 CD63 antigen isoform A [Homo sapiens]                       89   3e-18
gi|4757944 CD81 antigen [Homo sapiens]                                 88   8e-18
gi|30425534 tetraspanin 33 [Homo sapiens]                              87   1e-17
gi|91199546 CD63 antigen isoform B [Homo sapiens]                      86   2e-17
gi|67782354 CD82 antigen isoform 2 [Homo sapiens]                      85   6e-17

>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score =  489 bits (1258), Expect = e-138
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL 60
           MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL
Sbjct: 1   MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL 60

Query: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120
           IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL
Sbjct: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120

Query: 121 LVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
           LVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT
Sbjct: 121 LVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
           NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL
Sbjct: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240

Query: 241 Q 241
           Q
Sbjct: 241 Q 241


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score =  138 bits (347), Expect = 5e-33
 Identities = 86/254 (33%), Positives = 128/254 (50%), Gaps = 25/254 (9%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFG--PLSSSAMQFVNVGYFL 60
           C S +K +M +FN  IFL GA LLA+GIWV +D   F +I    PL       +   Y L
Sbjct: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPL------LLTGAYIL 58

Query: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120
           +A G ++F LGFLGC GA  E+KC L+ FF  +L+IF+AE++AA++A ++    E+    
Sbjct: 59  LAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIF---RENLTRE 115

Query: 121 LVVPAIKKDYGSQED---FTQVWNTTMKGLKCCGFTNYTDFEDSPYFK----ENSAFPPF 173
                + K Y    D   F+  WN+ M    CCG     DF+ +  F+    ++   P  
Sbjct: 116 FFTKELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEA 175

Query: 174 CC------NDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLEL 227
           CC       D V   + E C   ++     +GC+  +L    T     G +A G+  +EL
Sbjct: 176 CCRREPQSRDGVL-LSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIEL 234

Query: 228 AAMIVSMYLYCNLQ 241
            AMI +M L+  +Q
Sbjct: 235 FAMIFAMCLFRGIQ 248


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score =  127 bits (318), Expect = 1e-29
 Identities = 79/239 (33%), Positives = 118/239 (49%), Gaps = 25/239 (10%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFG--PLSSSAMQFVNVGYFL 60
           C S +K +M +FN  IFL GA LLA+GIWV +D   F +I    PL       +   Y L
Sbjct: 5   CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPL------LLTGAYIL 58

Query: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120
           +A G ++F LGFLGC GA  E+KC L+ FF  +L+IF+AE++AA++A ++    E+    
Sbjct: 59  LAMGGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIF---RENLTRE 115

Query: 121 LVVPAIKKDYGSQED---FTQVWNTTMKGLKCCGFTNYTDFEDSPYFK----ENSAFPPF 173
                + K Y    D   F+  WN+ M    CCG     DF+ +  F+    ++   P  
Sbjct: 116 FFTKELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEA 175

Query: 174 CC------NDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLE 226
           CC       D V   + E C   ++     +GC+  +L    T     G +A G+  +E
Sbjct: 176 CCRREPQSRDGVL-LSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  115 bits (288), Expect = 3e-26
 Identities = 73/236 (30%), Positives = 114/236 (48%), Gaps = 14/236 (5%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K MM LFNL+ +LCG  LL VGIW+S+   +F        S +   ++    +IA
Sbjct: 5   CLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATF-----SPSFPSLSAANLVIA 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVY-TTMAEHFLTLL 121
            G +V   GFLGC GA  E+KC L++FF +LL+I +AE+   ++  VY   + E+    L
Sbjct: 60  IGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDL 119

Query: 122 VVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTN 181
               +     +       WN     ++CCG T+YTD+   P   EN+  P  CC +N   
Sbjct: 120 KEGLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDW--YPVLGENTV-PDRCCMEN--- 173

Query: 182 TANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLY 237
             ++ C +         GC+ ++      N   +G V   I  +++  M  SM L+
Sbjct: 174 --SQGCGRNATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLF 227


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  112 bits (280), Expect = 3e-25
 Identities = 68/240 (28%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K +M  FNLL +L G  +L VGIW++    SF  +     SS+   ++    LI 
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL-----SSSFPSLSAANLLII 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G  V A+GF+GC GA  E+KC L+TFF +LLL+F+ E   A++   YT   + +    +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 123 VPAIKKDYGSQED--FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
              +   YG+Q +   T  W+      +CCG +NYTD+ +       +  P  CC +   
Sbjct: 120 KKGLHL-YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE---VYNATRVPDSCCLE--- 172

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
              +E+C            C+  +   ++ N + VG        +++  +  +M +YC +
Sbjct: 173 --FSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  112 bits (280), Expect = 3e-25
 Identities = 68/240 (28%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K +M  FNLL +L G  +L VGIW++    SF  +     SS+   ++    LI 
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL-----SSSFPSLSAANLLII 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G  V A+GF+GC GA  E+KC L+TFF +LLL+F+ E   A++   YT   + +    +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 123 VPAIKKDYGSQED--FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
              +   YG+Q +   T  W+      +CCG +NYTD+ +       +  P  CC +   
Sbjct: 120 KKGLHL-YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE---VYNATRVPDSCCLE--- 172

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
              +E+C            C+  +   ++ N + VG        +++  +  +M +YC +
Sbjct: 173 --FSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  112 bits (280), Expect = 3e-25
 Identities = 68/240 (28%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K +M  FNLL +L G  +L VGIW++    SF  +     SS+   ++    LI 
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL-----SSSFPSLSAANLLII 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G  V A+GF+GC GA  E+KC L+TFF +LLL+F+ E   A++   YT   + +    +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 123 VPAIKKDYGSQED--FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
              +   YG+Q +   T  W+      +CCG +NYTD+ +       +  P  CC +   
Sbjct: 120 KKGLHL-YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE---VYNATRVPDSCCLE--- 172

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
              +E+C            C+  +   ++ N + VG        +++  +  +M +YC +
Sbjct: 173 --FSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  112 bits (280), Expect = 3e-25
 Identities = 68/240 (28%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K +M  FNLL +L G  +L VGIW++    SF  +     SS+   ++    LI 
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL-----SSSFPSLSAANLLII 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G  V A+GF+GC GA  E+KC L+TFF +LLL+F+ E   A++   YT   + +    +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 123 VPAIKKDYGSQED--FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
              +   YG+Q +   T  W+      +CCG +NYTD+ +       +  P  CC +   
Sbjct: 120 KKGLHL-YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE---VYNATRVPDSCCLE--- 172

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
              +E+C            C+  +   ++ N + VG        +++  +  +M +YC +
Sbjct: 173 --FSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  112 bits (280), Expect = 3e-25
 Identities = 68/240 (28%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K +M  FNLL +L G  +L VGIW++    SF  +     SS+   ++    LI 
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL-----SSSFPSLSAANLLII 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G  V A+GF+GC GA  E+KC L+TFF +LLL+F+ E   A++   YT   + +    +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 123 VPAIKKDYGSQED--FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
              +   YG+Q +   T  W+      +CCG +NYTD+ +       +  P  CC +   
Sbjct: 120 KKGLHL-YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE---VYNATRVPDSCCLE--- 172

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
              +E+C            C+  +   ++ N + VG        +++  +  +M +YC +
Sbjct: 173 --FSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  112 bits (280), Expect = 3e-25
 Identities = 68/240 (28%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C   +K +M  FNLL +L G  +L VGIW++    SF  +     SS+   ++    LI 
Sbjct: 5   CLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL-----SSSFPSLSAANLLII 59

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G  V A+GF+GC GA  E+KC L+TFF +LLL+F+ E   A++   YT   + +    +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 123 VPAIKKDYGSQED--FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
              +   YG+Q +   T  W+      +CCG +NYTD+ +       +  P  CC +   
Sbjct: 120 KKGLHL-YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFE---VYNATRVPDSCCLE--- 172

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
              +E+C            C+  +   ++ N + VG        +++  +  +M +YC +
Sbjct: 173 --FSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQV 230


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  107 bits (267), Expect = 9e-24
 Identities = 78/247 (31%), Positives = 122/247 (49%), Gaps = 23/247 (9%)

Query: 6   FIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGV 65
           ++K ++ +FN   ++ GAA+LAVGIW  ++ + +L +   L+SS   F    Y LI AGV
Sbjct: 15  YLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSV---LASST--FAASAYILIFAGV 69

Query: 66  VVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPA 125
           +V   GFLG      E K  L T+F +LL+IF+ E+ A V+A VY       L   +   
Sbjct: 70  LVMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRT 129

Query: 126 IKKDYGSQEDFTQVW---NTTMKGLKCCGFTNYTDFEDSPYF----KENSAFPPFCCNDN 178
           + ++YG Q   TQ+    +   +  KCCG  +  D++ S Y      E    P  CC   
Sbjct: 130 LAENYG-QPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTV 188

Query: 179 VTNTANETCTKQKAHDQ---KVE-GCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSM 234
           V          Q+AH     KVE GC  +L   +  + + +G V  G+  L++  M+++ 
Sbjct: 189 VVRCG------QRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTC 242

Query: 235 YLYCNLQ 241
            L+  LQ
Sbjct: 243 CLHQRLQ 249


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  106 bits (265), Expect = 2e-23
 Identities = 74/253 (29%), Positives = 117/253 (46%), Gaps = 24/253 (9%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C    K  + LFNL+ F+ GA +L  G+W+  D +SF+ +    SSS        Y  I 
Sbjct: 5   CIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGA---YVFIG 61

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL-L 121
            G V   +GFLGC GA  E +C L  +F  LLLI IA+V A   AL Y  M +    +  
Sbjct: 62  VGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAG--ALFYFNMGKLKQEMGG 119

Query: 122 VVPAIKKDYGS--QEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYF--KENSAFPPFC--- 174
           +V  + +DY S  ++     W+     +KCCG+ ++ ++ D+     +    +P  C   
Sbjct: 120 IVTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVK 179

Query: 175 -CNDNVTNTANETC------TKQKAHDQK----VEGCFNQLLYDIRTNAVTVGGVAAGIG 223
              DN  +     C      T+   H +      EGC  ++   ++ N   + GV  G+ 
Sbjct: 180 GEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVA 239

Query: 224 GLELAAMIVSMYL 236
            +EL  M++S+ L
Sbjct: 240 IIELLGMVLSICL 252


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score =  105 bits (263), Expect = 3e-23
 Identities = 72/238 (30%), Positives = 111/238 (46%), Gaps = 15/238 (6%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           IK  M  FN L +LCG  +LA+ IWV +   S   IFG     +  +V V   LIA G +
Sbjct: 8   IKYSMFTFNFLFWLCGILILALAIWVRVSNDS-QAIFGSEDVGSSSYVAVD-ILIAVGAI 65

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFL--TLLVVP 124
           +  LGFLGC GA  ES+C L+ FF  LLLI + +VA  ++  V+ + ++  +  TL    
Sbjct: 66  IMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENT 125

Query: 125 AIKKDYG-SQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFC-CNDNVTNT 182
            +    G S++ F +      +  KCCG  N      + +      +P  C C D     
Sbjct: 126 KLLSATGESEKQFQEAIIVFQEEFKCCGLVNGA----ADWGNNFQHYPELCACLDK---- 177

Query: 183 ANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
               C          E C + +   +  N + V G++ G+  +E+  ++ SM LYC +
Sbjct: 178 -QRPCQSYNGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQI 234


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  105 bits (262), Expect = 4e-23
 Identities = 65/238 (27%), Positives = 112/238 (47%), Gaps = 23/238 (9%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           +KT++I+++ + ++ G  LLAVG+W  +   +++ +    S+      N  Y LI  G  
Sbjct: 15  LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENST------NAPYVLIGTGTT 68

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126
           +   G  GC+     S   L  +   L L+F+AE+ A +   V+    +         A+
Sbjct: 69  IVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAM 128

Query: 127 KKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTANET 186
           +  Y   ++ ++  +   + L CCG  NYT++  SPYF E+   PP CC        NET
Sbjct: 129 QT-YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEH-GIPPSCC-------MNET 179

Query: 187 -CTKQKAHDQKV-------EGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYL 236
            C  Q  H+  V       +GC++ +   + TN   + GVA GI   +L  M+++  L
Sbjct: 180 DCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCL 237


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  102 bits (255), Expect = 2e-22
 Identities = 71/238 (29%), Positives = 115/238 (48%), Gaps = 23/238 (9%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           CF   K++++++  + ++ G  LLAVGIW  +   S    F  L+  A    NV + LIA
Sbjct: 16  CF---KSVLLIYTFIFWITGVILLAVGIWGKV---SLENYFSLLNEKA---TNVPFVLIA 66

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G V+  LG  GC+     S   L  +   L L+F+ E+ AA+V  V+    ++      
Sbjct: 67  TGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNY 126

Query: 123 VPAIKKDYGSQEDF-TQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTN 181
             A+K+ Y S  D+ +   +     L CCG T+Y D+ D+ Y+ E   FP  CC      
Sbjct: 127 EKALKQ-YNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE-KGFPKSCCK----- 179

Query: 182 TANETCTKQKAHDQ-KVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYC 238
              E CT Q+  D+   EGCF +++  I +    V G++ G+   +L  + ++   YC
Sbjct: 180 --LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA---YC 232


>gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]
          Length = 245

 Score =  102 bits (253), Expect = 4e-22
 Identities = 67/224 (29%), Positives = 109/224 (48%), Gaps = 13/224 (5%)

Query: 4   FSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAA 63
           +S +K ++ L N  + + G  L+ +GI     GAS   + G LSS+ +  ++VG   +  
Sbjct: 8   YSSLKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLG-LSSAYL--LHVGNLCLVM 64

Query: 64  GVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMA-----EHFL 118
           G +   LG  G YGA  ES+  L+     ++++ I EV AA V L++  +      EH  
Sbjct: 65  GCITVLLGCAGWYGATKESRGTLLFCILSMVIVLIMEVTAATVVLLFFPIVGDVALEH-- 122

Query: 119 TLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPY-FKENSAFPPFCCND 177
           T + +    + Y   +D++  WN  M+ LKCCG  NYTDF  S +       +P  CC  
Sbjct: 123 TFVTLRKNYRGYNEPDDYSTQWNLVMEKLKCCGVNNYTDFSGSSFEMTTGHTYPRSCCKS 182

Query: 178 NVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAG 221
             + + +          QK  GCF++LL   +T + T+ G + G
Sbjct: 183 IGSVSCDGRDVSPNVIHQK--GCFHKLLKITKTQSFTLSGSSLG 224


>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score =  100 bits (250), Expect = 9e-22
 Identities = 66/236 (27%), Positives = 110/236 (46%), Gaps = 15/236 (6%)

Query: 8   KTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVV 67
           KT+++  NL+ +     L  VG +V I    +   F  + +     V     +IA G ++
Sbjct: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVV-----IIAVGALL 64

Query: 68  FALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIK 127
           F +G +GC     ES+C L TF  ILLL+F+ EV   V+  VY    E+ +   +    K
Sbjct: 65  FIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYK 124

Query: 128 KDYGSQED-FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKE--NSAFPPFCCNDNVTNTAN 184
              G+  D  ++  +   + L CCG  NY+D+E++ +FKE  N + P  CC +  +N   
Sbjct: 125 TYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASN--- 181

Query: 185 ETCTKQKAH--DQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYC 238
             C    AH  D   EGC   ++  ++   + V   A     ++L  M+ +  + C
Sbjct: 182 --CNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLC 235


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score =  100 bits (248), Expect = 1e-21
 Identities = 62/240 (25%), Positives = 110/240 (45%), Gaps = 32/240 (13%)

Query: 1   MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL 60
           M     +K ++  FNLL ++CG  +L  GI++ I   +F  +F  L S     + +G   
Sbjct: 3   MSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHN-NFGVLFHNLPS-----LTLGNVF 56

Query: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120
           +  G ++  + FLGC G+  E+KC L++FF +LL+I +AEV  A++  VY      ++  
Sbjct: 57  VIVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAK 116

Query: 121 LVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
            +  +I + Y S       W++    L+CCG    +D+   P        P  C      
Sbjct: 117 GLTDSIHR-YHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGP--------PASC------ 161

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
                        D+KVEGC+ +      +N + +G +   +  +E+  M  ++ L C +
Sbjct: 162 -----------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQI 210


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score =  100 bits (248), Expect = 1e-21
 Identities = 62/240 (25%), Positives = 110/240 (45%), Gaps = 32/240 (13%)

Query: 1   MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL 60
           M     +K ++  FNLL ++CG  +L  GI++ I   +F  +F  L S     + +G   
Sbjct: 3   MSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHN-NFGVLFHNLPS-----LTLGNVF 56

Query: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTL 120
           +  G ++  + FLGC G+  E+KC L++FF +LL+I +AEV  A++  VY      ++  
Sbjct: 57  VIVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAK 116

Query: 121 LVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVT 180
            +  +I + Y S       W++    L+CCG    +D+   P        P  C      
Sbjct: 117 GLTDSIHR-YHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGP--------PASC------ 161

Query: 181 NTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNL 240
                        D+KVEGC+ +      +N + +G +   +  +E+  M  ++ L C +
Sbjct: 162 -----------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQI 210


>gi|4502663 CD37 antigen isoform A [Homo sapiens]
          Length = 281

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 71/268 (26%), Positives = 115/268 (42%), Gaps = 34/268 (12%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C S IK  + +FNL  F+ G+ +   GIW+ ID  SF+   G L+   +Q  +    L  
Sbjct: 7   CLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVG-LAFVPLQIWS--KVLAI 63

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
           +G+    +  LGC GA  E +C L  +F +LLL+F  ++   ++        E  L  +V
Sbjct: 64  SGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVV 123

Query: 123 VPAIKKDYGSQEDFT---QVWNTTMKGLKCCGFTNYTDFEDSPYFKENSA----FPPFCC 175
              I+K YG+  + T   + W+     L+CCG+    D+      + N +     P  C 
Sbjct: 124 EKTIQK-YGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCY 182

Query: 176 NDNVTNTAN-----------------------ETCTKQKAHDQKVEGCFNQLLYDIRTNA 212
           N + TN +                        + C          EGC   L   +  N 
Sbjct: 183 NLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNL 242

Query: 213 VTVGGVAAGIGGLELAAMIVSMYLYCNL 240
           +++ G+  G+G LEL  M +S++L  NL
Sbjct: 243 ISIVGICLGVGLLELGFMTLSIFLCRNL 270


>gi|21264580 tetraspan 2 [Homo sapiens]
          Length = 221

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 72/238 (30%), Positives = 106/238 (44%), Gaps = 36/238 (15%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           IK +++ FNLL +L G+A++A G+W    GA  +K       S   F    Y L+ AG +
Sbjct: 11  IKYLLLGFNLLFWLAGSAVIAFGLWFRFGGA--IKELSSEDKSPEYFYVGLYVLVGAGAL 68

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126
           + A+GF GC GA  ES+C L +FF  LL+IF AEV   V A +   +A   +  +   A 
Sbjct: 69  MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAY 128

Query: 127 K---KDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTA 183
               KD G        +++T    +CCG             KE+S               
Sbjct: 129 NDYLKDRGKGNGTLITFHST---FQCCG-------------KESS------------EQV 160

Query: 184 NETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLQ 241
             TC K+       + C +++   I      +G V  GI GL +  MI SM L C ++
Sbjct: 161 QPTCPKELLGH---KNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIR 215


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 64/242 (26%), Positives = 107/242 (44%), Gaps = 15/242 (6%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           +K ++  +N   +L G A++AVGIW     + ++ +      ++  ++   Y L+ AG V
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLL-----ASGTYLATAYILVVAGTV 70

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126
           V   G LGC     E +  L  +F +LL+IF+ E+ A ++A  Y       L   +   +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 127 KKDY--GSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSA----FPPFCCNDNVT 180
            K Y     E  T   +   +   CCG  N  D+ DS + +   A     P  CC   V 
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NTANETCTKQKAHDQKVE-GCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCN 239
                      ++  KVE GC  +L   I+ +   +G V  GI  +++  MI +  LY +
Sbjct: 191 LCGQR---DHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247

Query: 240 LQ 241
           L+
Sbjct: 248 LK 249


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 64/242 (26%), Positives = 107/242 (44%), Gaps = 15/242 (6%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           +K ++  +N   +L G A++AVGIW     + ++ +      ++  ++   Y L+ AG V
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLL-----ASGTYLATAYILVVAGTV 70

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126
           V   G LGC     E +  L  +F +LL+IF+ E+ A ++A  Y       L   +   +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 127 KKDY--GSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSA----FPPFCCNDNVT 180
            K Y     E  T   +   +   CCG  N  D+ DS + +   A     P  CC   V 
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NTANETCTKQKAHDQKVE-GCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCN 239
                      ++  KVE GC  +L   I+ +   +G V  GI  +++  MI +  LY +
Sbjct: 191 LCGQR---DHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247

Query: 240 LQ 241
           L+
Sbjct: 248 LK 249


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 64/242 (26%), Positives = 107/242 (44%), Gaps = 15/242 (6%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           +K ++  +N   +L G A++AVGIW     + ++ +      ++  ++   Y L+ AG V
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLL-----ASGTYLATAYILVVAGTV 70

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126
           V   G LGC     E +  L  +F +LL+IF+ E+ A ++A  Y       L   +   +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 127 KKDY--GSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSA----FPPFCCNDNVT 180
            K Y     E  T   +   +   CCG  N  D+ DS + +   A     P  CC   V 
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NTANETCTKQKAHDQKVE-GCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCN 239
                      ++  KVE GC  +L   I+ +   +G V  GI  +++  MI +  LY +
Sbjct: 191 LCGQR---DHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247

Query: 240 LQ 241
           L+
Sbjct: 248 LK 249


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 64/242 (26%), Positives = 107/242 (44%), Gaps = 15/242 (6%)

Query: 7   IKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVV 66
           +K ++  +N   +L G A++AVGIW     + ++ +      ++  ++   Y L+ AG V
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLL-----ASGTYLATAYILVVAGTV 70

Query: 67  VFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAI 126
           V   G LGC     E +  L  +F +LL+IF+ E+ A ++A  Y       L   +   +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 127 KKDY--GSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSA----FPPFCCNDNVT 180
            K Y     E  T   +   +   CCG  N  D+ DS + +   A     P  CC   V 
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NTANETCTKQKAHDQKVE-GCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCN 239
                      ++  KVE GC  +L   I+ +   +G V  GI  +++  MI +  LY +
Sbjct: 191 LCGQR---DHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247

Query: 240 LQ 241
           L+
Sbjct: 248 LK 249


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 72/245 (29%), Positives = 111/245 (45%), Gaps = 33/245 (13%)

Query: 1   MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL 60
           M+C  F+  +++L       C   L+AVG+     GA  +     LS + +Q    G  L
Sbjct: 7   MKCVKFLLYVLLL---AFCACAVGLIAVGV-----GAQLV-----LSQTIIQGATPGSLL 53

Query: 61  ----IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVY--TTMA 114
               IA GV +F + F+GC GA  E+ C ++TF   L LI + EVAAA+   V+    M+
Sbjct: 54  PVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMS 113

Query: 115 E---HFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFP 171
           E   +F   +      ++Y        + +      KCCG  NYTD+E  P   +N   P
Sbjct: 114 EFNNNFRQQM------ENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRV-P 166

Query: 172 PFCCNDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMI 231
             CC  NVT        ++  H    EGC  ++   +R N + V   A GI  +E+  ++
Sbjct: 167 DSCC-INVTVGCGINFNEKAIHK---EGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIV 222

Query: 232 VSMYL 236
            +  L
Sbjct: 223 FACCL 227


>gi|4757944 CD81 antigen [Homo sapiens]
          Length = 236

 Score = 87.8 bits (216), Expect = 8e-18
 Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 25/245 (10%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSS-AMQFVNVG-YFL 60
           C   IK ++ +FN + +L G  +L V +W+  D  +   ++  L    A     VG Y L
Sbjct: 6   CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65

Query: 61  IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTM----AEH 116
           IA G V+  +GFLGCYGA  ES+C L TFF  L+++F  EVAA +   V         + 
Sbjct: 66  IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125

Query: 117 FLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCN 176
           F    +  A+  D     +   V  T  + L CCG +  T    S    +N+  P    +
Sbjct: 126 FYDQALQQAVVDD--DANNAKAVVKTFHETLDCCGSSTLTALTTS--VLKNNLCP--SGS 179

Query: 177 DNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYL 236
           + ++N   E C       QK++  F+  LY I   A+ V  +        +  MI+SM L
Sbjct: 180 NIISNLFKEDC------HQKIDDLFSGKLYLIGIAAIVVAVIM-------IFEMILSMVL 226

Query: 237 YCNLQ 241
            C ++
Sbjct: 227 CCGIR 231


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 68/254 (26%), Positives = 117/254 (46%), Gaps = 29/254 (11%)

Query: 4   FSFI----KTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYF 59
           FSF+    K ++  FN+L ++    ++AVG++  +       +    ++ A   V+    
Sbjct: 15  FSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARL-------MKHAEAALACLAVDPAIL 67

Query: 60  LIAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLT 119
           LI  GV++F L F GC G+  E+ C L TF   L  +F+ ++AA ++  V++  A   ++
Sbjct: 68  LIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVS 127

Query: 120 LLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYF--------KENSAFP 171
            ++  AI   Y    D   + +   K   CCG  +Y D+  + YF        +E  + P
Sbjct: 128 EIINNAI-VHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVP 186

Query: 172 PFCCNDNVTNTANETCTKQ--KAHD----QKV---EGCFNQLLYDIRTNAVTVGGVAAGI 222
             CC          T   Q  +A D     KV    GC ++L+  I +N   +GGVA G+
Sbjct: 187 YSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGL 246

Query: 223 GGLELAAMIVSMYL 236
              +L  +++S  L
Sbjct: 247 AIPQLVGILLSQIL 260


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 73/244 (29%), Positives = 109/244 (44%), Gaps = 36/244 (14%)

Query: 1   MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFL 60
           M+C  F+  +++L       C   L+AVG+     GA  +     LS + +Q    G  L
Sbjct: 7   MKCVKFLLYVLLL---AFCACAVGLIAVGV-----GAQLV-----LSQTIIQGATPGSLL 53

Query: 61  ----IAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVY--TTMA 114
               IA GV +F + F+GC GA  E+ C ++TF   L LI + EVAAA+   V+    M+
Sbjct: 54  PVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMS 113

Query: 115 E---HFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFP 171
           E   +F   +      ++Y        + +      KCCG  NYTD+E  P   +N   P
Sbjct: 114 EFNNNFRQQM------ENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRV-P 166

Query: 172 PFCCNDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIG---GLELA 228
             CC  NVT        ++  H    EGC  ++   +R N + V   A GI    G+  A
Sbjct: 167 DSCC-INVTVGCGINFNEKAIHK---EGCVEKIGGWLRKNVLVVAAAALGIAFVLGIVFA 222

Query: 229 AMIV 232
             +V
Sbjct: 223 CCLV 226


>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
          Length = 242

 Score = 84.7 bits (208), Expect = 6e-17
 Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 47/252 (18%)

Query: 3   CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIA 62
           C    K  + LFNL+ F+ GA +L  G+W+  D +SF+ +    SSS        Y  I 
Sbjct: 5   CIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRM---GAYVFIG 61

Query: 63  AGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLV 122
            G V   +GFLGC GA  E +C        LL +   E+   V  L+             
Sbjct: 62  VGAVTMLMGFLGCIGAVNEVRC--------LLGLLKQEMGGIVTELI------------- 100

Query: 123 VPAIKKDYGS--QEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYF--KENSAFPPFC---- 174
                +DY S  ++     W+     +KCCG+ ++ ++ D+     +    +P  C    
Sbjct: 101 -----RDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 155

Query: 175 CNDNVTNTANETC------TKQKAHDQK----VEGCFNQLLYDIRTNAVTVGGVAAGIGG 224
             DN  +     C      T+   H +      EGC  ++   ++ N   + GV  G+  
Sbjct: 156 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI 215

Query: 225 LELAAMIVSMYL 236
           +EL  M++S+ L
Sbjct: 216 IELLGMVLSICL 227


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,778,303
Number of Sequences: 37866
Number of extensions: 301487
Number of successful extensions: 1077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 953
Number of HSP's gapped (non-prelim): 54
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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