Search of human proteins with 212549753

Search of human proteins with 212549753

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212549753 calcium/calmodulin-dependent protein kinase II
delta isoform 5 [Homo sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|212549753 calcium/calmodulin-dependent protein kinase II delt...  1009   0.0  
gi|212549756 calcium/calmodulin-dependent protein kinase II delt...   971   0.0  
gi|26667183 calcium/calmodulin-dependent protein kinase II delta...   969   0.0  
gi|26667186 calcium/calmodulin-dependent protein kinase II delta...   969   0.0  
gi|26667180 calcium/calmodulin-dependent protein kinase II delta...   969   0.0  
gi|26667189 calcium/calmodulin-dependent protein kinase II delta...   967   0.0  
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ...   895   0.0  
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma...   893   0.0  
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ...   890   0.0  
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma...   885   0.0  
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ...   881   0.0  
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma...   880   0.0  
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ...   880   0.0  
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ...   877   0.0  
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma...   873   0.0  
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma...   863   0.0  
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha...   857   0.0  
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha...   856   0.0  
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ...   825   0.0  
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ...   824   0.0  
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ...   639   0.0  
gi|186700629 calcium/calmodulin-dependent serine protein kinase ...   286   4e-77
gi|186700627 calcium/calmodulin-dependent serine protein kinase ...   286   4e-77
gi|186972120 calcium/calmodulin-dependent serine protein kinase ...   286   4e-77
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ...   250   2e-66
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...   236   5e-62
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...   236   5e-62
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...   228   1e-59
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo...   226   4e-59
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca...   224   1e-58

>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
           isoform 5 [Homo sapiens]
          Length = 492

 Score = 1009 bits (2608), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480

Query: 481 FHRSGSPTVPIK 492
           FHRSGSPTVPIK
Sbjct: 481 FHRSGSPTVPIK 492


>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
           isoform 4 [Homo sapiens]
          Length = 489

 Score =  971 bits (2509), Expect = 0.0
 Identities = 478/492 (97%), Positives = 483/492 (98%), Gaps = 3/492 (0%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLLKKPDGVK+ +++   +     ESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKKRKSS---SSVQMMESTESSNTTIEDEDVKAR 357

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 358 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 417

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 418 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 477

Query: 481 FHRSGSPTVPIK 492
           FHRSGSPTVPIK
Sbjct: 478 FHRSGSPTVPIK 489


>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
           isoform 1 [Homo sapiens]
          Length = 478

 Score =  969 bits (2504), Expect = 0.0
 Identities = 478/492 (97%), Positives = 478/492 (97%), Gaps = 14/492 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLLKKPDGV              KESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGV--------------KESTESSNTTIEDEDVKAR 346

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 347 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 406

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 407 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 466

Query: 481 FHRSGSPTVPIK 492
           FHRSGSPTVPIK
Sbjct: 467 FHRSGSPTVPIK 478


>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
           isoform 1 [Homo sapiens]
          Length = 478

 Score =  969 bits (2504), Expect = 0.0
 Identities = 478/492 (97%), Positives = 478/492 (97%), Gaps = 14/492 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLLKKPDGV              KESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGV--------------KESTESSNTTIEDEDVKAR 346

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 347 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 406

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 407 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 466

Query: 481 FHRSGSPTVPIK 492
           FHRSGSPTVPIK
Sbjct: 467 FHRSGSPTVPIK 478


>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
           isoform 3 [Homo sapiens]
          Length = 499

 Score =  969 bits (2504), Expect = 0.0
 Identities = 478/492 (97%), Positives = 478/492 (97%), Gaps = 14/492 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLLKKPDGV              KESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGV--------------KESTESSNTTIEDEDVKAR 346

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 347 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 406

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 407 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 466

Query: 481 FHRSGSPTVPIK 492
           FHRSGSPTVPIK
Sbjct: 467 FHRSGSPTVPIK 478


>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
           isoform 2 [Homo sapiens]
          Length = 478

 Score =  967 bits (2499), Expect = 0.0
 Identities = 477/491 (97%), Positives = 477/491 (97%), Gaps = 14/491 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLLKKPDGV              KESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGV--------------KESTESSNTTIEDEDVKAR 346

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 347 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 406

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 407 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 466

Query: 481 FHRSGSPTVPI 491
           FHRSGSPTVPI
Sbjct: 467 FHRSGSPTVPI 477


>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
           isoform 3 [Homo sapiens]
          Length = 518

 Score =  895 bits (2312), Expect = 0.0
 Identities = 438/518 (84%), Positives = 469/518 (90%), Gaps = 26/518 (5%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVK------------------------EPQTTVI 335
           KGAILTTMLATRNFSAAKSLL KK DGVK                        EPQTTVI
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 360

Query: 336 HNP-DGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 394
           HNP DG KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+F
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 420

Query: 395 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 454
           EPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 421 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480

Query: 455 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 492
            G P+T QSEETRVWHRRDGKWQNVHFH SG+P  P++
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 518


>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
           isoform 4 [Homo sapiens]
          Length = 495

 Score =  893 bits (2307), Expect = 0.0
 Identities = 432/495 (87%), Positives = 463/495 (93%), Gaps = 3/495 (0%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPD--GVKEPQTTVIHN-PDGNKESTESSNTTIEDEDV 357
           KGAILTTML +RNFSAAKSLL K    GVKEPQTTV+HN  DG K STES NTT EDED+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360

Query: 358 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 417
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420

Query: 418 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 477
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480

Query: 478 NVHFHRSGSPTVPIK 492
           NVH+H SG+P  P++
Sbjct: 481 NVHYHCSGAPAAPLQ 495


>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
           isoform 4 [Homo sapiens]
          Length = 517

 Score =  890 bits (2301), Expect = 0.0
 Identities = 434/517 (83%), Positives = 465/517 (89%), Gaps = 25/517 (4%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVK------------------------EPQTTVIH 336
           KGAILTTMLATRNFSA   L KK DGVK                        EPQTTVIH
Sbjct: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360

Query: 337 NP-DGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 395
           NP DG KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FE
Sbjct: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420

Query: 396 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 455
           PEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG 
Sbjct: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480

Query: 456 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 492
           G P+T QSEETRVWHRRDGKWQNVHFH SG+P  P++
Sbjct: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517


>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
           isoform 6 [Homo sapiens]
          Length = 504

 Score =  885 bits (2287), Expect = 0.0
 Identities = 432/504 (85%), Positives = 463/504 (91%), Gaps = 12/504 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPD--GVK---------EPQTTVIHN-PDGNKESTESS 348
           KGAILTTML +RNFSAAKSLL K    GVK         EPQTTV+HN  DG K STES 
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360

Query: 349 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 408
           NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420

Query: 409 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 468
           H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480

Query: 469 WHRRDGKWQNVHFHRSGSPTVPIK 492
           WHRRDGKW NVH+H SG+P  P++
Sbjct: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504


>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
           isoform 5 [Homo sapiens]
          Length = 503

 Score =  881 bits (2276), Expect = 0.0
 Identities = 430/504 (85%), Positives = 461/504 (91%), Gaps = 13/504 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVKEPQTTVIHN-----------PDGNKESTESS 348
           KGAILTTMLATRNFSAAKSLL KK DGVK PQT    N           P    ES++S+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVK-PQTNSTKNSAAATSPKGTLPPAALESSDSA 359

Query: 349 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 408
           NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDF
Sbjct: 360 NTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDF 419

Query: 409 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 468
           HRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 420 HRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 479

Query: 469 WHRRDGKWQNVHFHRSGSPTVPIK 492
           WHRRDGKWQNVHFH SG+P  P++
Sbjct: 480 WHRRDGKWQNVHFHCSGAPVAPLQ 503


>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
           isoform 3 [Homo sapiens]
          Length = 518

 Score =  880 bits (2274), Expect = 0.0
 Identities = 432/518 (83%), Positives = 463/518 (89%), Gaps = 26/518 (5%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLL-KKPDG------------------------VKEPQTTVI 335
           KGAILTTML +RNFSAAKSLL KK DG                          EPQTTV+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360

Query: 336 HN-PDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 394
           HN  DG K STES NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+F
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 420

Query: 395 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 454
           EPEALGNLVEGMDFH+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 421 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480

Query: 455 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 492
            G P+T QSEETRVWHRRDGKW NVH+H SG+P  P++
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 518


>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
           isoform 2 [Homo sapiens]
          Length = 542

 Score =  880 bits (2273), Expect = 0.0
 Identities = 437/542 (80%), Positives = 468/542 (86%), Gaps = 50/542 (9%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
           KGAILTTMLATRNFS                         AKSLL KK DGVK       
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360

Query: 329 -----------------EPQTTVIHNP-DGNKESTESSNTTIEDEDVKARKQEIIKVTEQ 370
                            EPQTTVIHNP DG KES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420

Query: 371 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 430
           LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480

Query: 431 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 490
           PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P  P
Sbjct: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540

Query: 491 IK 492
           ++
Sbjct: 541 LQ 542


>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
           isoform 7 [Homo sapiens]
          Length = 479

 Score =  877 bits (2265), Expect = 0.0
 Identities = 423/492 (85%), Positives = 454/492 (92%), Gaps = 13/492 (2%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFSAAKSLL K               DG KES++S+NTTIEDED KAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNK-------------KADGVKESSDSANTTIEDEDAKAR 347

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K+
Sbjct: 348 KQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKN 407

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           +KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVH
Sbjct: 408 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVH 467

Query: 481 FHRSGSPTVPIK 492
           FH SG+P  P++
Sbjct: 468 FHCSGAPVAPLQ 479


>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
           isoform 2 [Homo sapiens]
          Length = 527

 Score =  873 bits (2255), Expect = 0.0
 Identities = 432/527 (81%), Positives = 464/527 (88%), Gaps = 35/527 (6%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLATRNFS---------------------AAKSLL-KKPDG------------ 326
           KGAILTTML +RNFS                     AAKSLL KK DG            
Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVH 360

Query: 327 VKEPQTTVIHN-PDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTK 385
           + EPQTTV+HN  DG K STES NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTK
Sbjct: 361 LMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK 420

Query: 386 ICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAY 445
           ICDPGLT+FEPEALGNLVEGMDFH+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAY
Sbjct: 421 ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY 480

Query: 446 IRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 492
           IRLTQY+DG G P+T QSEETRVWHRRDGKW NVH+H SG+P  P++
Sbjct: 481 IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527


>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
           isoform 1 [Homo sapiens]
          Length = 556

 Score =  863 bits (2229), Expect = 0.0
 Identities = 433/556 (77%), Positives = 464/556 (83%), Gaps = 64/556 (11%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLL-KKPDG------------------------VKEPQTTVI 335
           KGAILTTML +RNFSAAKSLL KK DG                          EPQTTV+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360

Query: 336 HN-PDGNKESTESSNTTIEDEDVKA----------------------------------- 359
           HN  DG K STES NTT EDED+KA                                   
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420

Query: 360 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 416
              RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN 
Sbjct: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480

Query: 417 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 476
           LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW
Sbjct: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540

Query: 477 QNVHFHRSGSPTVPIK 492
            NVH+H SG+P  P++
Sbjct: 541 LNVHYHCSGAPAAPLQ 556


>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
           isoform 1 [Homo sapiens]
          Length = 489

 Score =  857 bits (2215), Expect = 0.0
 Identities = 415/488 (85%), Positives = 453/488 (92%), Gaps = 4/488 (0%)

Query: 3   STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
           +T TCTRFT+EYQLFEELGKGAFSVVRRC+K+  GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 2   ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61

Query: 63  RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
           RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 62  RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121

Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
           +V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181

Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
           PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241

Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
           PEAKDLINKMLTINP+KRITA+EALKHPWI  RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301

Query: 303 AILTTMLATRNFSAAKS-LLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKARK 361
           AILTTMLATRNFS  KS   KK DGVK+ +++   +     ES+ES+NTTIEDED K RK
Sbjct: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSS---SSVQLMESSESTNTTIEDEDTKVRK 358

Query: 362 QEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSN 421
           QEIIKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN  S+++
Sbjct: 359 QEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNS 418

Query: 422 KPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHF 481
           KP+HT ILNPH+HL+GD++ACIAYIR+TQY+D  G+P+T QSEETRVWHRRDGKWQ VHF
Sbjct: 419 KPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHF 478

Query: 482 HRSGSPTV 489
           HRSG+P+V
Sbjct: 479 HRSGAPSV 486


>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
           isoform 2 [Homo sapiens]
          Length = 478

 Score =  856 bits (2211), Expect = 0.0
 Identities = 413/487 (84%), Positives = 446/487 (91%), Gaps = 13/487 (2%)

Query: 3   STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
           +T TCTRFT+EYQLFEELGKGAFSVVRRC+K+  GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 2   ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61

Query: 63  RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
           RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 62  RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121

Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
           +V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181

Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
           PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241

Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
           PEAKDLINKMLTINP+KRITA+EALKHPWI  RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301

Query: 303 AILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQ 362
           AILTTMLATRNFS  KS   K               DG KES+ES+NTTIEDED K RKQ
Sbjct: 302 AILTTMLATRNFSGGKSGGNK-------------KSDGVKESSESTNTTIEDEDTKVRKQ 348

Query: 363 EIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNK 422
           EIIKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN  S+++K
Sbjct: 349 EIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSK 408

Query: 423 PIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFH 482
           P+HT ILNPH+HL+GD++ACIAYIR+TQY+D  G+P+T QSEETRVWHRRDGKWQ VHFH
Sbjct: 409 PVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFH 468

Query: 483 RSGSPTV 489
           RSG+P+V
Sbjct: 469 RSGAPSV 475


>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
           isoform 6 [Homo sapiens]
          Length = 492

 Score =  825 bits (2132), Expect = 0.0
 Identities = 412/518 (79%), Positives = 442/518 (85%), Gaps = 52/518 (10%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVKEPQTTVI 335
           KGAILTTMLATRNFS                         AKSLL KK DGVKEPQTTVI
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKEPQTTVI 360

Query: 336 HNP-DGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 394
           HNP DG KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY           
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA---------- 410

Query: 395 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 454
                           FYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 411 ----------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 454

Query: 455 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 492
            G P+T QSEETRVWHRRDGKWQNVHFH SG+P  P++
Sbjct: 455 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 492


>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
           isoform 8 [Homo sapiens]
          Length = 449

 Score =  824 bits (2128), Expect = 0.0
 Identities = 401/492 (81%), Positives = 429/492 (87%), Gaps = 43/492 (8%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
           KGAILTTMLATRNFS                                           AR
Sbjct: 301 KGAILTTMLATRNFS-------------------------------------------AR 317

Query: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
           KQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K+
Sbjct: 318 KQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKN 377

Query: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
           +KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVH
Sbjct: 378 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVH 437

Query: 481 FHRSGSPTVPIK 492
           FH SG+P  P++
Sbjct: 438 FHCSGAPVAPLQ 449


>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
           isoform 1 [Homo sapiens]
          Length = 666

 Score =  639 bits (1647), Expect = 0.0
 Identities = 327/409 (79%), Positives = 345/409 (84%), Gaps = 50/409 (12%)

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
           LE+V HCH  G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
           KGAILTTMLATRNFS                         AKSLL KK DGVK       
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360

Query: 329 -----------------EPQTTVIHNP-DGNKESTESSNTTIEDEDVKA 359
                            EPQTTVIHNP DG KES++S+NTTIEDED KA
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA 409



 Score =  246 bits (627), Expect = 4e-65
 Identities = 110/134 (82%), Positives = 124/134 (92%)

Query: 359 ARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALS 418
           +RKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+
Sbjct: 533 SRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 592

Query: 419 KSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQN 478
           K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQN
Sbjct: 593 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 652

Query: 479 VHFHRSGSPTVPIK 492
           VHFH SG+P  P++
Sbjct: 653 VHFHCSGAPVAPLQ 666


>gi|186700629 calcium/calmodulin-dependent serine protein kinase
           isoform 3 [Homo sapiens]
          Length = 897

 Score =  286 bits (731), Expect = 4e-77
 Identities = 146/306 (47%), Positives = 206/306 (67%), Gaps = 8/306 (2%)

Query: 10  FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR---DHQKLEREARICR 66
           F D Y+L E +GKG FSVVRRC+   TGQ++A KI++  K ++      + L+REA IC 
Sbjct: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
           +LKHP+IV L ++ S +G  Y+VF+ + G +L  +IV R      YSEA ASH ++QILE
Sbjct: 68  MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127

Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
           ++ +CH N I+HRD+KP  +LLASK   A VKL  FG+AI++        G  GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187

Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
           PEV++++PYGKPVD+W CGVIL+ILL G  PF+   + RL++ I  G Y     +W  ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246

Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
             AKDL+ +ML ++PA+RIT  EAL HPW+ +R   A  +H  ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306

Query: 303 AILTTM 308
           A+L  +
Sbjct: 307 AVLAAV 312


>gi|186700627 calcium/calmodulin-dependent serine protein kinase
           isoform 2 [Homo sapiens]
          Length = 898

 Score =  286 bits (731), Expect = 4e-77
 Identities = 146/306 (47%), Positives = 206/306 (67%), Gaps = 8/306 (2%)

Query: 10  FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR---DHQKLEREARICR 66
           F D Y+L E +GKG FSVVRRC+   TGQ++A KI++  K ++      + L+REA IC 
Sbjct: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
           +LKHP+IV L ++ S +G  Y+VF+ + G +L  +IV R      YSEA ASH ++QILE
Sbjct: 68  MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127

Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
           ++ +CH N I+HRD+KP  +LLASK   A VKL  FG+AI++        G  GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187

Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
           PEV++++PYGKPVD+W CGVIL+ILL G  PF+   + RL++ I  G Y     +W  ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246

Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
             AKDL+ +ML ++PA+RIT  EAL HPW+ +R   A  +H  ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306

Query: 303 AILTTM 308
           A+L  +
Sbjct: 307 AVLAAV 312


>gi|186972120 calcium/calmodulin-dependent serine protein kinase
           isoform 1 [Homo sapiens]
          Length = 921

 Score =  286 bits (731), Expect = 4e-77
 Identities = 146/306 (47%), Positives = 206/306 (67%), Gaps = 8/306 (2%)

Query: 10  FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR---DHQKLEREARICR 66
           F D Y+L E +GKG FSVVRRC+   TGQ++A KI++  K ++      + L+REA IC 
Sbjct: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
           +LKHP+IV L ++ S +G  Y+VF+ + G +L  +IV R      YSEA ASH ++QILE
Sbjct: 68  MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127

Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
           ++ +CH N I+HRD+KP  +LLASK   A VKL  FG+AI++        G  GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187

Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
           PEV++++PYGKPVD+W CGVIL+ILL G  PF+   + RL++ I  G Y     +W  ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246

Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
             AKDL+ +ML ++PA+RIT  EAL HPW+ +R   A  +H  ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306

Query: 303 AILTTM 308
           A+L  +
Sbjct: 307 AVLAAV 312


>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
           sapiens]
          Length = 473

 Score =  250 bits (638), Expect = 2e-66
 Identities = 148/383 (38%), Positives = 223/383 (58%), Gaps = 26/383 (6%)

Query: 11  TDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
           +D +++  ELG+GA S+V RC +  T + YA K++        D + +  E  +   L H
Sbjct: 43  SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98

Query: 71  PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130
           PNI++L +         LV +LVTGGELF+ IV + YYSE DA+  ++QILE+V + H N
Sbjct: 99  PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158

Query: 131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP 190
           GIVHRDLKPENLL A+ +  A +K+ADFGL+ ++   Q       GTPGY +PE+LR   
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217

Query: 191 YGKPVDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248
           YG  VDMW+ G+I YILL G+ PF+DE  DQ  ++++I    Y F SP WD V+  AKDL
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276

Query: 249 INKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTM 308
           + K++ ++P KR+T  +AL+HPW+  ++  A+ +H       L++FNARRKLK A+   +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334

Query: 309 LATRNFSAAKS---------LLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKA 359
            ++R  SA+ S           + P  +++    +   P+G K   + +        VK 
Sbjct: 335 ASSRLGSASSSHGSIQESHKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAA-----VKG 389

Query: 360 RKQEIIKVTEQLIEAINNGDFEA 382
            + E++KV  Q +E +   D  A
Sbjct: 390 AQAELMKV--QALEKVKGADINA 410


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score =  236 bits (601), Expect = 5e-62
 Identities = 124/294 (42%), Positives = 177/294 (60%), Gaps = 3/294 (1%)

Query: 14  YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           ++  E LG GAFS V    +  TG+ +A K I  K L  ++   +E E  + R +KH NI
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIV 133
           V L D        YLV  LV+GGELF+ IV + +Y+E DAS  I+Q+L++V + H  GIV
Sbjct: 82  VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141

Query: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK 193
           HRDLKPENLL  S+ + + + ++DFGL+ +++G         GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200

Query: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
            VD W+ GVI YILL GYPPF+DE+  +L++QI    Y+F SP WD ++  AKD I  ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260

Query: 254 TINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTT 307
             +P KR T  +A +HPWI   + +   +H   +    K F A+ K + A   T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score =  236 bits (601), Expect = 5e-62
 Identities = 124/294 (42%), Positives = 177/294 (60%), Gaps = 3/294 (1%)

Query: 14  YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           ++  E LG GAFS V    +  TG+ +A K I  K L  ++   +E E  + R +KH NI
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIV 133
           V L D        YLV  LV+GGELF+ IV + +Y+E DAS  I+Q+L++V + H  GIV
Sbjct: 82  VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141

Query: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK 193
           HRDLKPENLL  S+ + + + ++DFGL+ +++G         GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200

Query: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
            VD W+ GVI YILL GYPPF+DE+  +L++QI    Y+F SP WD ++  AKD I  ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260

Query: 254 TINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTT 307
             +P KR T  +A +HPWI   + +   +H   +    K F A+ K + A   T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
           sapiens]
          Length = 370

 Score =  228 bits (581), Expect = 1e-59
 Identities = 125/296 (42%), Positives = 175/296 (59%), Gaps = 3/296 (1%)

Query: 12  DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           D Y   + LG GAFS V       T +  A K I  + L  ++   +E E  +   +KHP
Sbjct: 18  DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131
           NIV L D     G  YL+  LV+GGELF+ IV + +Y+E DAS  I Q+L++V + H  G
Sbjct: 77  NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136

Query: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY 191
           IVHRDLKPENLL  S  + + + ++DFGL+ +++          GTPGY++PEVL + PY
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195

Query: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251
            K VD W+ GVI YILL GYPPF+DE+  +L++QI    Y+F SP WD ++  AKD I  
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255

Query: 252 MLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTT 307
           ++  +P KR T  +AL+HPWI   + +   +H Q   + +KK  A+ K K A   T
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNAT 310


>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
           sapiens]
          Length = 476

 Score =  226 bits (576), Expect = 4e-59
 Identities = 122/266 (45%), Positives = 162/266 (60%), Gaps = 6/266 (2%)

Query: 8   TRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRL 67
           T     +   E LG GAFS V    +  TG+ +A K I  KK  A     LE E  + + 
Sbjct: 17  TNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCI--KKSPAFRDSSLENEIAVLKK 74

Query: 68  LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
           +KH NIV L D       +YLV  LV+GGELF+ I+ R  Y+E DAS  IQQ+L +V + 
Sbjct: 75  IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134

Query: 128 HLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLSPEVL 186
           H NGIVHRDLKPENLL  +  + + + + DFGL+ +E  G         GTPGY++PEVL
Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMST---ACGTPGYVAPEVL 191

Query: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
            + PY K VD W+ GVI YILL GYPPF++E + +L+++IK G Y+F SP WD ++  AK
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251

Query: 247 DLINKMLTINPAKRITASEALKHPWI 272
           D I  +L  +P +R T  +AL HPWI
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWI 277


>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
           kinase isoform b [Homo sapiens]
          Length = 360

 Score =  224 bits (571), Expect = 1e-58
 Identities = 120/260 (46%), Positives = 161/260 (61%), Gaps = 5/260 (1%)

Query: 14  YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           Y++ E LG GAFS V    +  +    A K I  K L  ++   +E E  + R + HPNI
Sbjct: 32  YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 90

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIV 133
           V L D        YL  +LVTGGELF+ I+ R  Y+E DASH + Q+L +V++ H  GIV
Sbjct: 91  VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150

Query: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GTPGYLSPEVLRKDPYG 192
           HRDLKPENLL A+  + + + ++DFGL+    G+     G A GTPGY++PE+L + PYG
Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 207

Query: 193 KPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 252
           K VD+WA GVI YILL GYPPF+DE    L+ QI   +Y+F SP WD ++  AKD I  +
Sbjct: 208 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 267

Query: 253 LTINPAKRITASEALKHPWI 272
           L  +P KR T  +AL+H WI
Sbjct: 268 LERDPQKRFTCQQALRHLWI 287


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,273,445
Number of Sequences: 37866
Number of extensions: 870851
Number of successful extensions: 4746
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 578
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 2311
Number of HSP's gapped (non-prelim): 1055
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.