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Search of human proteins with 211059433
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|211059433 coiled-coil domain containing 79 [Homo sapiens]
(727 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|211059433 coiled-coil domain containing 79 [Homo sapiens] 1472 0.0
gi|39812229 karyopherin alpha 5 [Homo sapiens] 47 8e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 40 0.008
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 40 0.008
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 39 0.017
gi|71061468 centromere protein E [Homo sapiens] 39 0.022
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 38 0.038
gi|222144293 karyopherin alpha 1 [Homo sapiens] 37 0.050
gi|40538794 coiled-coil domain containing 21 [Homo sapiens] 37 0.065
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 36 0.11
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 36 0.11
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 36 0.14
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 35 0.19
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 35 0.19
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 35 0.19
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 35 0.19
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 35 0.19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 35 0.19
gi|94557295 mitogen-activated protein kinase 8 interacting prote... 35 0.25
gi|94557297 mitogen-activated protein kinase 8 interacting prote... 35 0.25
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 35 0.32
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens] 35 0.32
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens] 35 0.32
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] 35 0.32
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens] 35 0.32
gi|4557040 oncostatin M receptor [Homo sapiens] 34 0.42
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] 34 0.42
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 34 0.42
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 34 0.42
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 34 0.42
>gi|211059433 coiled-coil domain containing 79 [Homo sapiens]
Length = 727
Score = 1472 bits (3810), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MESEDTKKTQEMKTDLNLLLECLKYQMDNAFSQKEALVTIHSICQQNSNASVYFREIGGL 60
MESEDTKKTQEMKTDLNLLLECLKYQMDNAFSQKEALVTIHSICQQNSNASVYFREIGGL
Sbjct: 1 MESEDTKKTQEMKTDLNLLLECLKYQMDNAFSQKEALVTIHSICQQNSNASVYFREIGGL 60
Query: 61 MFVKNLAKSSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKR 120
MFVKNLAKSSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKR
Sbjct: 61 MFVKNLAKSSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKR 120
Query: 121 MSVYVILVLVSNNRTGQTLVRETGCITVLSRLFRTVISKHELDLSDKNVFQSYQLWSSVC 180
MSVYVILVLVSNNRTGQTLVRETGCITVLSRLFRTVISKHELDLSDKNVFQSYQLWSSVC
Sbjct: 121 MSVYVILVLVSNNRTGQTLVRETGCITVLSRLFRTVISKHELDLSDKNVFQSYQLWSSVC 180
Query: 181 STLCVCVNNPQNDENQMFCCSLFPHANEWLKNCTTPEIIRPICSFIGLTLANNTYVQKYF 240
STLCVCVNNPQNDENQMFCCSLFPHANEWLKNCTTPEIIRPICSFIGLTLANNTYVQKYF
Sbjct: 181 STLCVCVNNPQNDENQMFCCSLFPHANEWLKNCTTPEIIRPICSFIGLTLANNTYVQKYF 240
Query: 241 VSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFGIVLSKYHIVSKL 300
VSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFGIVLSKYHIVSKL
Sbjct: 241 VSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFGIVLSKYHIVSKL 300
Query: 301 LALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELNKAA 360
LALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELNKAA
Sbjct: 301 LALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELNKAA 360
Query: 361 TFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLER 420
TFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLER
Sbjct: 361 TFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLER 420
Query: 421 EGNEEEIQRENYQDNISSMNISIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGV 480
EGNEEEIQRENYQDNISSMNISIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGV
Sbjct: 421 EGNEEEIQRENYQDNISSMNISIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGV 480
Query: 481 MSKACTNDDQMKTPLKSANPVHACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSS 540
MSKACTNDDQMKTPLKSANPVHACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSS
Sbjct: 481 MSKACTNDDQMKTPLKSANPVHACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSS 540
Query: 541 DHVFKHPVHIAKNIKQQLPVTDPFTLCSDIINKEVVSFLATPSCSEMLTYRCSGCIAVEK 600
DHVFKHPVHIAKNIKQQLPVTDPFTLCSDIINKEVVSFLATPSCSEMLTYRCSGCIAVEK
Sbjct: 541 DHVFKHPVHIAKNIKQQLPVTDPFTLCSDIINKEVVSFLATPSCSEMLTYRCSGCIAVEK 600
Query: 601 SLNSRNFSKLLHSCPYQCDRHKVIVEAEDRYKSELRKSLICNKKILLTPRRRQRLSNEST 660
SLNSRNFSKLLHSCPYQCDRHKVIVEAEDRYKSELRKSLICNKKILLTPRRRQRLSNEST
Sbjct: 601 SLNSRNFSKLLHSCPYQCDRHKVIVEAEDRYKSELRKSLICNKKILLTPRRRQRLSNEST 660
Query: 661 TPGGIKKRRIRKNFTEEEVNYLFNGVKKMGNHWNSILWSFPFQQGRKAVDLAHKYHKLTK 720
TPGGIKKRRIRKNFTEEEVNYLFNGVKKMGNHWNSILWSFPFQQGRKAVDLAHKYHKLTK
Sbjct: 661 TPGGIKKRRIRKNFTEEEVNYLFNGVKKMGNHWNSILWSFPFQQGRKAVDLAHKYHKLTK 720
Query: 721 HPTCAAS 727
HPTCAAS
Sbjct: 721 HPTCAAS 727
>gi|39812229 karyopherin alpha 5 [Homo sapiens]
Length = 539
Score = 46.6 bits (109), Expect = 8e-05
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Query: 61 MFVKNLAKSSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKR 120
+F+K L +SEH V+E A++ LG IA N C+ + E+ L L+N + + R
Sbjct: 174 IFIKLL--NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTR 231
Query: 121 MSVYVILVLVSNNRTGQTLVRETGCITVLSRL 152
+V+ + L + + C+ VLSRL
Sbjct: 232 NAVWALSNLCRGKNPPPNFSKVSPCLNVLSRL 263
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 40.0 bits (92), Expect = 0.008
Identities = 78/353 (22%), Positives = 139/353 (39%), Gaps = 65/353 (18%)
Query: 350 ESQNEELNKAATFV----------LHNCKKIT-----EKLSLSLGEYPFDENETQQLKDI 394
E +N+ L+K + L NC+ ++ EK L EN +Q+K I
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK-I 555
Query: 395 SVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADR 454
+EN EH + L + Q+ E ++I++EN ++ SI+ T L
Sbjct: 556 LEQEN---EHLNQTVSSLRQRSQISAEARVKDIEKEN-----KILHESIKETSSKL---- 603
Query: 455 IGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMKTPLKSANPVHACYRESE-QNKT 513
SK E E + ++L+ YK G ++ N+ +H +E+E K
Sbjct: 604 ----SKIEFEKRQIKKELEHYKEKGERAEELENE------------LHHLEKENELLQKK 647
Query: 514 LYKAKSSCNQNLHEETTFEKNFVSQSSDHVFKHPVHIAKNIKQQLPVTDPFTLCSDIINK 573
+ K +C + E ++N + + K + KN+ QL + D N
Sbjct: 648 ITNLKITCEK---IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 574 EVVSFLATPSCSEMLTYRCSGCIAVEKSLNS-----RNFSKLLHSCPYQCDRHKVIVEAE 628
E+ + + C+ M + + K L S + +LL + + +R +V +
Sbjct: 705 ELRRNVESLKCASM---KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Query: 629 DRYKSELRKSL-ICNKKILLTPRRRQRLSNESTTPGGIKKRRIRKNFTEEEVN 680
D L+K+L NKKI Q L E+ T ++KN E +++
Sbjct: 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQT--------LQKNLEELKIS 806
Score = 35.4 bits (80), Expect = 0.19
Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 28/165 (16%)
Query: 350 ESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQ---------------QLKDI 394
ES+ E+L K + + KK TE+L +S + Q +L+D+
Sbjct: 731 ESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL 789
Query: 395 SVKENNLEEHWRKAKEILHRIEQLEREG---NEEEIQRENYQDNISSMN------ISIQN 445
++ L+++ + K R+EQLE+E +E Q E + + N I++
Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 446 TWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQ 490
T + +IG E E+K+ S+++ YK V K +++
Sbjct: 850 TTLEENNVKIG---NLEKENKTLSKEIGIYKESCVRLKELEKENK 891
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 40.0 bits (92), Expect = 0.008
Identities = 78/353 (22%), Positives = 139/353 (39%), Gaps = 65/353 (18%)
Query: 350 ESQNEELNKAATFV----------LHNCKKIT-----EKLSLSLGEYPFDENETQQLKDI 394
E +N+ L+K + L NC+ ++ EK L EN +Q+K I
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK-I 555
Query: 395 SVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADR 454
+EN EH + L + Q+ E ++I++EN ++ SI+ T L
Sbjct: 556 LEQEN---EHLNQTVSSLRQRSQISAEARVKDIEKEN-----KILHESIKETSSKL---- 603
Query: 455 IGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMKTPLKSANPVHACYRESE-QNKT 513
SK E E + ++L+ YK G ++ N+ +H +E+E K
Sbjct: 604 ----SKIEFEKRQIKKELEHYKEKGERAEELENE------------LHHLEKENELLQKK 647
Query: 514 LYKAKSSCNQNLHEETTFEKNFVSQSSDHVFKHPVHIAKNIKQQLPVTDPFTLCSDIINK 573
+ K +C + E ++N + + K + KN+ QL + D N
Sbjct: 648 ITNLKITCEK---IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 574 EVVSFLATPSCSEMLTYRCSGCIAVEKSLNS-----RNFSKLLHSCPYQCDRHKVIVEAE 628
E+ + + C+ M + + K L S + +LL + + +R +V +
Sbjct: 705 ELRRNVESLKCASM---KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Query: 629 DRYKSELRKSL-ICNKKILLTPRRRQRLSNESTTPGGIKKRRIRKNFTEEEVN 680
D L+K+L NKKI Q L E+ T ++KN E +++
Sbjct: 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQT--------LQKNLEELKIS 806
Score = 35.4 bits (80), Expect = 0.19
Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 28/165 (16%)
Query: 350 ESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQ---------------QLKDI 394
ES+ E+L K + + KK TE+L +S + Q +L+D+
Sbjct: 731 ESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL 789
Query: 395 SVKENNLEEHWRKAKEILHRIEQLEREG---NEEEIQRENYQDNISSMN------ISIQN 445
++ L+++ + K R+EQLE+E +E Q E + + N I++
Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 446 TWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQ 490
T + +IG E E+K+ S+++ YK V K +++
Sbjct: 850 TTLEENNVKIG---NLEKENKTLSKEIGIYKESCVRLKELEKENK 891
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 38.9 bits (89), Expect = 0.017
Identities = 42/214 (19%), Positives = 99/214 (46%), Gaps = 26/214 (12%)
Query: 352 QNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENET----QQLKDISVKENNLEEHWRK 407
+ +EL L + + ++L+ L + E E ++L+DI + +LE +
Sbjct: 524 EKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKN 583
Query: 408 AKEILHRIE-QLEREG---NEEEIQRENYQDNISSMN----------ISIQNTWKHLHAD 453
+ + +HR+E +L+++ ++ ++++ + ++ I+ + + +Q + K L A
Sbjct: 584 SLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAI 643
Query: 454 RIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQ---MKTPLKSANPVHACYRE-SE 509
R +K +E+++ L+ + ++A + D++ + T LK VH RE +
Sbjct: 644 RADLANKLAEEERAKKAVLKDLSD--LTAQAKSRDEETATIITQLKLERDVH--QRELKD 699
Query: 510 QNKTLYKAKSSCNQNLHEETTFEKNFVSQSSDHV 543
+L K+ QN+ E K S++ +H+
Sbjct: 700 LTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHI 733
Score = 33.1 bits (74), Expect = 0.94
Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 384 DENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISI 443
D + L++++ K N ++ + + R+++LERE E E QD + M++ +
Sbjct: 193 DAETKRALEELTEKLNEAQKQEVVSDRVERRLQELEREMRTERELVERRQDQLGLMSLQL 252
Query: 444 QNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKS 477
Q K A + + E K+ RQ ++ K+
Sbjct: 253 QEALKKQEA----KADEHEGAIKNKLRQTETEKN 282
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 38.5 bits (88), Expect = 0.022
Identities = 41/211 (19%), Positives = 88/211 (41%), Gaps = 23/211 (10%)
Query: 372 EKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQREN 431
E ++LS FD + ++S K L+E R+ +E L+ +EQL+ + + +
Sbjct: 846 EIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQT 905
Query: 432 YQDNISSMNISIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKS------HGVMSKAC 485
+ + + +Q T + + ++ +D+ K LQ + H ++
Sbjct: 906 VEREKTLITEKLQQT-----LEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI 960
Query: 486 TNDDQMKTPLKSANPVHACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSSDHVFK 545
+Q++ L+S + +T+ KS ++ + E+N ++ D +
Sbjct: 961 DTQEQLRNALESL---------KQHQETINTLKSKISEEVSRNLHMEEN-TGETKDEFQQ 1010
Query: 546 HPVHIAKNIKQQLPVTDPFTLCSDIINKEVV 576
V I K KQ L + TL +D+ + E++
Sbjct: 1011 KMVGIDK--KQDLEAKNTQTLTADVKDNEII 1039
Score = 30.0 bits (66), Expect = 7.9
Identities = 30/151 (19%), Positives = 57/151 (37%), Gaps = 10/151 (6%)
Query: 389 QQLKDISVKENNLEEHWRKA----KEILHRIEQLEREGNEEEIQRENYQDNISSMNISIQ 444
+ +K+I K EE + A KE I +L +E+E + Q + ++N +Q
Sbjct: 1463 ENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQ 1522
Query: 445 NTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMK------TPLKSA 498
N + ++ K E + +L+ +K H + + K +S
Sbjct: 1523 NKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQ 1582
Query: 499 NPVHACYRESEQNKTLYKAKSSCNQNLHEET 529
+ +E E+ K + +A L E T
Sbjct: 1583 EEIQIMIKEKEEMKRVQEALQIERDQLKENT 1613
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 37.7 bits (86), Expect = 0.038
Identities = 48/220 (21%), Positives = 87/220 (39%), Gaps = 20/220 (9%)
Query: 345 IQALTESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEH 404
++ + E E LN LHN E+ L + EN + L+D +V+ N +E
Sbjct: 340 LKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDL-QKQHTENIQELLEDTNVRLNKMESE 398
Query: 405 W--------RKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADRIG 456
+ KE+ R++QL E +QR+ + + Q T L +
Sbjct: 399 YMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKAR 458
Query: 457 RGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMKTPLKSANPVHACYRESEQN----- 511
R + +++D + Q+ K A N + + L SA+ + E EQN
Sbjct: 459 RNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHAL-SASKASSMIEELEQNVCQLK 517
Query: 512 KTLYKAKSSCNQNLHEETTFEKNFVSQSS--DHVFKHPVH 549
+ L +++ Q L ++ E F + S H+++ H
Sbjct: 518 QQLQESELQRKQQLRDQ---ENKFQMEKSHLKHIYEKKAH 554
>gi|222144293 karyopherin alpha 1 [Homo sapiens]
Length = 538
Score = 37.4 bits (85), Expect = 0.050
Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
Query: 20 LECLKYQMDNAFSQKEALVTIHSICQQNSNASVYFREIGGL-MFVKNLAKSSEHSMVKEA 78
+E LK + +N Q E+ + +I NS + + G + +F++ L SSE V+E
Sbjct: 132 VEFLK-RKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELL--SSEFEDVQEQ 188
Query: 79 ALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKRMSVYVILVLVSNNRTGQT 138
A++ LG IA + C+ + + L S + + + R +V+ + L
Sbjct: 189 AVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPE 248
Query: 139 LVRETGCITVLSRL 152
+ + C+ VLS L
Sbjct: 249 FAKVSPCLNVLSWL 262
>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
Length = 762
Score = 37.0 bits (84), Expect = 0.065
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 15/182 (8%)
Query: 385 ENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQD---NISSMNI 441
+ ++QQLKD +K L+E K E+ +E+ + E+EIQ E+ + SS
Sbjct: 493 QKQSQQLKDSELKSTELQE---KVTELESLLEETQAICREKEIQLESLRQREAEFSSAGH 549
Query: 442 SIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMKTPLKSANPV 501
S+Q+ K + G G + E E S ++ S + ++ K DQ+++ ++S
Sbjct: 550 SLQD--KQSVEETSGEGPEVEME--SWQKRYDSLQK--IVEKQQQKMDQLRSQVQSLEQE 603
Query: 502 HACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSSDHVFKHPVHIAKNIKQQLPVT 561
A +E ++ L + + L + T K Q+ D + K+ + + ++++Q P +
Sbjct: 604 VA--QEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKN-LTLQEHLRQAQPGS 660
Query: 562 DP 563
P
Sbjct: 661 PP 662
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 36.2 bits (82), Expect = 0.11
Identities = 46/213 (21%), Positives = 92/213 (43%), Gaps = 18/213 (8%)
Query: 337 KNNGLPLMIQALTESQNEELNKAATFVLHNCK--KITEKLSLSLGEYPFDENETQQLKDI 394
+ N IQAL E E+ + AT ++ K K + L+++L +++ ++++++
Sbjct: 284 ERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMAL------KSKEKKVEEL 337
Query: 395 SVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADR 454
+ + L + KA+E L + + E +G+E+ + ++ +S+ + QN K R
Sbjct: 338 NSEIEKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAA-LRSQNLTKSTENHR 396
Query: 455 IGRGSKAEDEDKSHSRQLQS------YKSHGVMSKA-CTNDDQMKTPLKSANPVHACYRE 507
+ R K ++ S +Q + ++H SK CT D K N V+ RE
Sbjct: 397 LRRSIKKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNE--RE 454
Query: 508 SEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSS 540
S N+ LH + K+ ++
Sbjct: 455 KAMENRYKSLLSESNKKLHNQEQVIKHLTESTN 487
Score = 30.4 bits (67), Expect = 6.1
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 351 SQNEELNKAATFVLHNCKKITEKLSLSLGEYPFD-ENETQQLKD-ISVKENNLEEHWRKA 408
+ EL+ + T +H +K + L+ L + D + E +L++ +S K +LE R+
Sbjct: 1439 ASGSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREY 1498
Query: 409 KEILHRIEQLEREGNEEEIQRENYQ 433
+ E+L++EG+E+E R N Q
Sbjct: 1499 ASVKEENERLQKEGSEKE--RHNQQ 1521
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 36.2 bits (82), Expect = 0.11
Identities = 46/213 (21%), Positives = 92/213 (43%), Gaps = 18/213 (8%)
Query: 337 KNNGLPLMIQALTESQNEELNKAATFVLHNCK--KITEKLSLSLGEYPFDENETQQLKDI 394
+ N IQAL E E+ + AT ++ K K + L+++L +++ ++++++
Sbjct: 284 ERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMAL------KSKEKKVEEL 337
Query: 395 SVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADR 454
+ + L + KA+E L + + E +G+E+ + ++ +S+ + QN K R
Sbjct: 338 NSEIEKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAA-LRSQNLTKSTENHR 396
Query: 455 IGRGSKAEDEDKSHSRQLQS------YKSHGVMSKA-CTNDDQMKTPLKSANPVHACYRE 507
+ R K ++ S +Q + ++H SK CT D K N V+ RE
Sbjct: 397 LRRSIKKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNE--RE 454
Query: 508 SEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSS 540
S N+ LH + K+ ++
Sbjct: 455 KAMENRYKSLLSESNKKLHNQEQVIKHLTESTN 487
Score = 30.4 bits (67), Expect = 6.1
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 351 SQNEELNKAATFVLHNCKKITEKLSLSLGEYPFD-ENETQQLKD-ISVKENNLEEHWRKA 408
+ EL+ + T +H +K + L+ L + D + E +L++ +S K +LE R+
Sbjct: 1439 ASGSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREY 1498
Query: 409 KEILHRIEQLEREGNEEEIQRENYQ 433
+ E+L++EG+E+E R N Q
Sbjct: 1499 ASVKEENERLQKEGSEKE--RHNQQ 1521
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapiens]
Length = 1692
Score = 35.8 bits (81), Expect = 0.14
Identities = 40/171 (23%), Positives = 63/171 (36%), Gaps = 23/171 (13%)
Query: 383 FDENETQQLKDISVKENNLE-------EHWRKAKEILHRIEQLEREGNEEEIQRENYQDN 435
F +QL + V+ ++E E R+ K +HR +Q G+ +E+ RE Y
Sbjct: 1263 FSSRRGRQLPQVPVRSGSIEQASLVVEERTRQMKMKVHRFKQTTGSGSSQELDREQY--- 1319
Query: 436 ISSMNISIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMKTP- 494
S N K + +K+ D D S + S +S +Q + P
Sbjct: 1320 ------SKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFMSEQSERPR 1373
Query: 495 --LKSANPVHACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSSDHV 543
+ S P R +++ K+ S E T E N SQS V
Sbjct: 1374 GRISSFTPKMQGRRMGTSGRSIMKSTSVSG----EMYTLEHNDGSQSDTAV 1420
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 35.4 bits (80), Expect = 0.19
Identities = 42/193 (21%), Positives = 78/193 (40%), Gaps = 19/193 (9%)
Query: 385 ENETQQLK-DISVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSM---N 440
++E L+ ++ KE L + + + ++ IE+L+R+ E +D +S
Sbjct: 466 DSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEG 525
Query: 441 ISIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTND---DQMKTPLKS 497
SI + K D R + ED+ +++L K + S+ ND + K K
Sbjct: 526 DSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKV 585
Query: 498 ANPVHACYRESEQNKTLYKAKSSCNQNL---HEETTFEKNFVSQS---------SDHVFK 545
N V + E N ++ K +++ EE + +N + QS D + K
Sbjct: 586 ENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLK 645
Query: 546 HPVHIAKNIKQQL 558
+N+KQ L
Sbjct: 646 EREAEVRNLKQNL 658
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 35.4 bits (80), Expect = 0.19
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 44/254 (17%)
Query: 229 TLANNTYVQKYFVSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFG 288
TL K + ++ G D+ ++LE +S ++ + DNP G
Sbjct: 266 TLTERLLKMKDWAAMLGEDITDDDNLELEMNS--------------ESENGAYLDNPPKG 311
Query: 289 IVLSKYHIVSKLLALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQAL 348
+ H +KL A L ++L+ GE+ I + L + +E + KN
Sbjct: 312 ALKKLIH-AAKLNASL--KTLE-GERNQIYIQLSE-VDKTKEELTEHIKN---------- 356
Query: 349 TESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKEN-NLEEHWRK 407
+++ L T + +K+ +KL + Y ENE + + ++V+EN LE+ +
Sbjct: 357 LQTEQASLQSENTHFENENQKLQQKLKVMTELY--QENEMKLHRKLTVEENYRLEKEEKL 414
Query: 408 AK---EILHRIEQLE-----REGNEEEIQR--ENYQDNISSMNISIQNTWKHLHADRIGR 457
+K +I H E+LE + EEE++R +YQ I S + W L A R
Sbjct: 415 SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNW--LAARNAER 472
Query: 458 GSKAEDEDKSHSRQ 471
++ +H+RQ
Sbjct: 473 NLNDLRKENAHNRQ 486
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 35.4 bits (80), Expect = 0.19
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 44/254 (17%)
Query: 229 TLANNTYVQKYFVSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFG 288
TL K + ++ G D+ ++LE +S ++ + DNP G
Sbjct: 266 TLTERLLKMKDWAAMLGEDITDDDNLELEMNS--------------ESENGAYLDNPPKG 311
Query: 289 IVLSKYHIVSKLLALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQAL 348
+ H +KL A L ++L+ GE+ I + L + +E + KN
Sbjct: 312 ALKKLIH-AAKLNASL--KTLE-GERNQIYIQLSE-VDKTKEELTEHIKN---------- 356
Query: 349 TESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKEN-NLEEHWRK 407
+++ L T + +K+ +KL + Y ENE + + ++V+EN LE+ +
Sbjct: 357 LQTEQASLQSENTHFENENQKLQQKLKVMTELY--QENEMKLHRKLTVEENYRLEKEEKL 414
Query: 408 AK---EILHRIEQLE-----REGNEEEIQR--ENYQDNISSMNISIQNTWKHLHADRIGR 457
+K +I H E+LE + EEE++R +YQ I S + W L A R
Sbjct: 415 SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNW--LAARNAER 472
Query: 458 GSKAEDEDKSHSRQ 471
++ +H+RQ
Sbjct: 473 NLNDLRKENAHNRQ 486
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 35.4 bits (80), Expect = 0.19
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 44/254 (17%)
Query: 229 TLANNTYVQKYFVSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFG 288
TL K + ++ G D+ ++LE +S ++ + DNP G
Sbjct: 237 TLTERLLKMKDWAAMLGEDITDDDNLELEMNS--------------ESENGAYLDNPPKG 282
Query: 289 IVLSKYHIVSKLLALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQAL 348
+ H +KL A L ++L+ GE+ I + L + +E + KN
Sbjct: 283 ALKKLIH-AAKLNASL--KTLE-GERNQIYIQLSE-VDKTKEELTEHIKN---------- 327
Query: 349 TESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKEN-NLEEHWRK 407
+++ L T + +K+ +KL + Y ENE + + ++V+EN LE+ +
Sbjct: 328 LQTEQASLQSENTHFENENQKLQQKLKVMTELY--QENEMKLHRKLTVEENYRLEKEEKL 385
Query: 408 AK---EILHRIEQLE-----REGNEEEIQR--ENYQDNISSMNISIQNTWKHLHADRIGR 457
+K +I H E+LE + EEE++R +YQ I S + W L A R
Sbjct: 386 SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNW--LAARNAER 443
Query: 458 GSKAEDEDKSHSRQ 471
++ +H+RQ
Sbjct: 444 NLNDLRKENAHNRQ 457
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 35.4 bits (80), Expect = 0.19
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 44/254 (17%)
Query: 229 TLANNTYVQKYFVSVGGLDVLSQVLMQLESDSHETLSSAKLAVVVTKTVDACIADNPTFG 288
TL K + ++ G D+ ++LE +S ++ + DNP G
Sbjct: 254 TLTERLLKMKDWAAMLGEDITDDDNLELEMNS--------------ESENGAYLDNPPKG 299
Query: 289 IVLSKYHIVSKLLALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQAL 348
+ H +KL A L ++L+ GE+ I + L + +E + KN
Sbjct: 300 ALKKLIH-AAKLNASL--KTLE-GERNQIYIQLSE-VDKTKEELTEHIKN---------- 344
Query: 349 TESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKEN-NLEEHWRK 407
+++ L T + +K+ +KL + Y ENE + + ++V+EN LE+ +
Sbjct: 345 LQTEQASLQSENTHFENENQKLQQKLKVMTELY--QENEMKLHRKLTVEENYRLEKEEKL 402
Query: 408 AK---EILHRIEQLE-----REGNEEEIQR--ENYQDNISSMNISIQNTWKHLHADRIGR 457
+K +I H E+LE + EEE++R +YQ I S + W L A R
Sbjct: 403 SKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNW--LAARNAER 460
Query: 458 GSKAEDEDKSHSRQ 471
++ +H+RQ
Sbjct: 461 NLNDLRKENAHNRQ 474
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 35.4 bits (80), Expect = 0.19
Identities = 43/202 (21%), Positives = 73/202 (36%), Gaps = 31/202 (15%)
Query: 365 HNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNE 424
HN + S S G + E ++ D K+ K+K QLE + NE
Sbjct: 477 HNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK-------QLESKSNE 529
Query: 425 EEIQRENYQDNISSMNISIQNTWKHLHA------------DRIGR-GSKAEDEDKSHSRQ 471
+ + +D + + K H+ DR R S+ D D+S S++
Sbjct: 530 HDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKE 589
Query: 472 LQSYKSHGVMSKACTNDDQMKTP---------LKSANPVHACYRESEQ--NKTLYKAKSS 520
Y+ + + + +TP + + RE Q NK Y+ + S
Sbjct: 590 YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES 649
Query: 521 CNQNLHEETTFEKNFVSQSSDH 542
+ + E + EK S+S DH
Sbjct: 650 KSSHRKENSESEKRMYSKSRDH 671
>gi|94557295 mitogen-activated protein kinase 8 interacting protein
3 isoform 2 [Homo sapiens]
Length = 1330
Score = 35.0 bits (79), Expect = 0.25
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 17/149 (11%)
Query: 344 MIQALTESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEE 403
+I E +EL VL N + + E + +QL +E L
Sbjct: 43 LIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALR- 101
Query: 404 HWRKAKEILHRIEQ-LEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADRIGRGSKAE 462
R+A+E E LE+E E +IQ E+Y+ + + +N +AD+I R + E
Sbjct: 102 --RQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKN-----YADQISRLEERE 154
Query: 463 DEDKS--------HSRQLQSYKSHGVMSK 483
E K H+ +Q+Y H SK
Sbjct: 155 SEMKKEYNALHQRHTEMIQTYVEHIERSK 183
>gi|94557297 mitogen-activated protein kinase 8 interacting protein
3 isoform 1 [Homo sapiens]
Length = 1336
Score = 35.0 bits (79), Expect = 0.25
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 17/149 (11%)
Query: 344 MIQALTESQNEELNKAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDISVKENNLEE 403
+I E +EL VL N + + E + +QL +E L
Sbjct: 43 LIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALR- 101
Query: 404 HWRKAKEILHRIEQ-LEREGNEEEIQRENYQDNISSMNISIQNTWKHLHADRIGRGSKAE 462
R+A+E E LE+E E +IQ E+Y+ + + +N +AD+I R + E
Sbjct: 102 --RQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKN-----YADQISRLEERE 154
Query: 463 DEDKS--------HSRQLQSYKSHGVMSK 483
E K H+ +Q+Y H SK
Sbjct: 155 SEMKKEYNALHQRHTEMIQTYVEHIERSK 183
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 34.7 bits (78), Expect = 0.32
Identities = 63/292 (21%), Positives = 115/292 (39%), Gaps = 39/292 (13%)
Query: 308 SLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELNKAATFVLHNC 367
SL E F + +G T+ +E YD GL ++ + + +AAT +
Sbjct: 1104 SLADLEAFMKVARMG-LTKPLKEGDYD-----GL---VEVMGHLMKVKERQAATDNMFEP 1154
Query: 368 KKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLER--EGNEE 425
K T +L + GE + ++I +K L EHW K++ +++ + NE
Sbjct: 1155 LKQTIELLKTYGE--------EMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEV 1206
Query: 426 EIQRENYQDNISSMNISIQNTWKHLHADRIGRGSKAEDED----KSHSRQLQSYKS-HGV 480
I R Q +H +R R + D KS ++Q +S + G+
Sbjct: 1207 SILRRKCQQF---------ELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGI 1257
Query: 481 MSKACTNDDQMKTPLKSANPVHACYRESEQNKTLYKAKSSCNQNLHE-ETTFEKNFVSQS 539
M + + P+ + AC+RE K L+ N ++ + +TT K+ +
Sbjct: 1258 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317
Query: 540 SDHVFKHPVHIAKNIKQQLPVTDPF-----TLCSDIINKEVVSFLATPSCSE 586
D K +++ +++ D F T+ + I + VS L P+ E
Sbjct: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRE 1369
>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
Length = 541
Score = 34.7 bits (78), Expect = 0.32
Identities = 40/199 (20%), Positives = 82/199 (41%), Gaps = 13/199 (6%)
Query: 368 KKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEI 427
KK+ E+L + Y ++ + +Q+++ N E + + + +IE+ ++ + E
Sbjct: 101 KKLHEELCILKRSY--EKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEK 158
Query: 428 QRENYQDNISSMNI---SIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQ--SYKSHGVMS 482
QR YQ +SS+ ++ + + A + R K E + S ++Q S K
Sbjct: 159 QRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERAND 218
Query: 483 KACTNDDQMKTPLKSANPV----HACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQ 538
C N+ +++ N + +E +Q + + + L EE E Q
Sbjct: 219 TICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKR-ELKAALQ 277
Query: 539 SSDHVFKHPVHIAKNIKQQ 557
S +++ H I K Q+
Sbjct: 278 SQENLI-HEARIQKEKLQE 295
>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
Length = 703
Score = 34.7 bits (78), Expect = 0.32
Identities = 40/199 (20%), Positives = 82/199 (41%), Gaps = 13/199 (6%)
Query: 368 KKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEI 427
KK+ E+L + Y ++ + +Q+++ N E + + + +IE+ ++ + E
Sbjct: 101 KKLHEELCILKRSY--EKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEK 158
Query: 428 QRENYQDNISSMNI---SIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQ--SYKSHGVMS 482
QR YQ +SS+ ++ + + A + R K E + S ++Q S K
Sbjct: 159 QRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERAND 218
Query: 483 KACTNDDQMKTPLKSANPV----HACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQ 538
C N+ +++ N + +E +Q + + + L EE E Q
Sbjct: 219 TICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKR-ELKAALQ 277
Query: 539 SSDHVFKHPVHIAKNIKQQ 557
S +++ H I K Q+
Sbjct: 278 SQENLI-HEARIQKEKLQE 295
>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
Length = 475
Score = 34.7 bits (78), Expect = 0.32
Identities = 40/199 (20%), Positives = 82/199 (41%), Gaps = 13/199 (6%)
Query: 368 KKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEI 427
KK+ E+L + Y ++ + +Q+++ N E + + + +IE+ ++ + E
Sbjct: 101 KKLHEELCILKRSY--EKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEK 158
Query: 428 QRENYQDNISSMNI---SIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQ--SYKSHGVMS 482
QR YQ +SS+ ++ + + A + R K E + S ++Q S K
Sbjct: 159 QRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERAND 218
Query: 483 KACTNDDQMKTPLKSANPV----HACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQ 538
C N+ +++ N + +E +Q + + + L EE E Q
Sbjct: 219 TICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKR-ELKAALQ 277
Query: 539 SSDHVFKHPVHIAKNIKQQ 557
S +++ H I K Q+
Sbjct: 278 SQENLI-HEARIQKEKLQE 295
>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
Length = 495
Score = 34.7 bits (78), Expect = 0.32
Identities = 40/199 (20%), Positives = 82/199 (41%), Gaps = 13/199 (6%)
Query: 368 KKITEKLSLSLGEYPFDENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEI 427
KK+ E+L + Y ++ + +Q+++ N E + + + +IE+ ++ + E
Sbjct: 101 KKLHEELCILKRSY--EKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEK 158
Query: 428 QRENYQDNISSMNI---SIQNTWKHLHADRIGRGSKAEDEDKSHSRQLQ--SYKSHGVMS 482
QR YQ +SS+ ++ + + A + R K E + S ++Q S K
Sbjct: 159 QRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERAND 218
Query: 483 KACTNDDQMKTPLKSANPV----HACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQ 538
C N+ +++ N + +E +Q + + + L EE E Q
Sbjct: 219 TICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKR-ELKAALQ 277
Query: 539 SSDHVFKHPVHIAKNIKQQ 557
S +++ H I K Q+
Sbjct: 278 SQENLI-HEARIQKEKLQE 295
>gi|4557040 oncostatin M receptor [Homo sapiens]
Length = 979
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/138 (21%), Positives = 58/138 (42%), Gaps = 9/138 (6%)
Query: 459 SKAEDEDKSHSRQLQSYKSHGVMSKACTNDDQMKTPL---KSANPVHACYRESEQNKTLY 515
SK +E K S + + +K+ CT D T L K + + + K L
Sbjct: 234 SKVLEEPKDFSCETEDFKT-----LHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLC 288
Query: 516 KAKSSCNQNLHEETTFEKNFVSQSSDHVFKHPVHIAKNIKQQLPVTDPFTLCSDIIN-KE 574
K+ CN + +++ NF + +++ K V+I N+ ++ + +PF++ + +N
Sbjct: 289 THKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATN 348
Query: 575 VVSFLATPSCSEMLTYRC 592
+ S TY C
Sbjct: 349 AIMTWKVHSIRNNFTYLC 366
>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
Length = 1019
Score = 34.3 bits (77), Expect = 0.42
Identities = 38/153 (24%), Positives = 69/153 (45%), Gaps = 14/153 (9%)
Query: 258 SDSHETLSSAKLA--VVVTKT-VDACIADNPTFGIVLSKYHIVSKLLALLLHESLDSG-- 312
S S + AK+A V ++KT ++ +D P G +S + S + L H D
Sbjct: 505 SSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNI 564
Query: 313 -EKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELNKAATFVLHNCKKIT 371
E F + + G + + ++++ + L I+ L +SQN+ L T L CK
Sbjct: 565 QEIFQTLYSHGSAISESKIREFEV-ETERLNSRIEHL-KSQNDLL----TITLEECKSNA 618
Query: 372 EKLSLSLGEYPFDENETQQLKDISVKENNLEEH 404
E++S+ +G+Y + N T + E +E +
Sbjct: 619 ERMSMLVGKY--ESNATALRLALQYSEQCIEAY 649
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 34.3 bits (77), Expect = 0.42
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 29/149 (19%)
Query: 298 SKLLALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELN 357
SK+ A +L +L S E+ + L ENQ+D F + + T++ E+
Sbjct: 905 SKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEK-----MTSFTKTAREQYE 959
Query: 358 KAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDI-------------SVKENN---- 400
K +T +HN KL +LGEY +++T +++ +V+ENN
Sbjct: 960 KLST--MHNNMM---KLYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRRE 1014
Query: 401 LEEHWRKAKEILHRIEQ--LEREGNEEEI 427
+EE R+AK + EQ LER+ ++++
Sbjct: 1015 MEEKTRRAKLAKEKAEQEKLERQKKKKQL 1043
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 34.3 bits (77), Expect = 0.42
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 29/149 (19%)
Query: 298 SKLLALLLHESLDSGEKFSIMLTLGHCTEDCEENQYDLFKNNGLPLMIQALTESQNEELN 357
SK+ A +L +L S E+ + L ENQ+D F + + T++ E+
Sbjct: 905 SKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEK-----MTSFTKTAREQYE 959
Query: 358 KAATFVLHNCKKITEKLSLSLGEYPFDENETQQLKDI-------------SVKENN---- 400
K +T +HN KL +LGEY +++T +++ +V+ENN
Sbjct: 960 KLST--MHNNMM---KLYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRRE 1014
Query: 401 LEEHWRKAKEILHRIEQ--LEREGNEEEI 427
+EE R+AK + EQ LER+ ++++
Sbjct: 1015 MEEKTRRAKLAKEKAEQEKLERQKKKKQL 1043
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 34.3 bits (77), Expect = 0.42
Identities = 40/184 (21%), Positives = 82/184 (44%), Gaps = 24/184 (13%)
Query: 384 DENETQQLKDISVKENNLEEHWRKAKEILHRIEQLEREGNEEEIQRENYQDNISSMNISI 443
DE E ++L+ K ++L+E + K+ E L + + E+E N ++IQR N + +
Sbjct: 1513 DEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKE-NNDKIQRLNEE-------LEK 1564
Query: 444 QNTWKHLHADRIGRGSKAEDEDKSHSRQLQSYKSHGVMSKACTND---------DQMKTP 494
N + ++ ++ +E K +++Q+ + V+ K D K
Sbjct: 1565 SNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQ 1624
Query: 495 LKSANPVHACYRESEQNKTLYKAKSSCNQNLHEETTFEKNFVSQSSDHVFKHPVHIAKNI 554
L+S N ++EQ+ ++ K C L E+ +N VS+ + + I +N
Sbjct: 1625 LRSTNEHLHKQTKTEQD---FQRKIKC---LEEDLAKSQNLVSEFKQKCDQQNI-IIQNT 1677
Query: 555 KQQL 558
K+++
Sbjct: 1678 KKEV 1681
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.130 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,333,449
Number of Sequences: 37866
Number of extensions: 1135123
Number of successful extensions: 4293
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 4186
Number of HSP's gapped (non-prelim): 242
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.