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Search of human proteins with 21070976
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21070976 diablo isoform 3 precursor [Homo sapiens]
(195 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21070976 diablo isoform 3 precursor [Homo sapiens] 386 e-108
gi|9845297 diablo isoform 1 precursor [Homo sapiens] 365 e-101
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 40 0.001
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 40 0.001
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 40 0.001
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 40 0.001
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 40 0.001
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 40 0.001
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 40 0.001
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 40 0.001
gi|197313718 IQ motif containing G [Homo sapiens] 38 0.005
gi|14165288 IQ motif containing G [Homo sapiens] 38 0.005
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 35 0.040
gi|89357932 keratin 5b [Homo sapiens] 35 0.040
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 35 0.040
gi|110611218 ribosome binding protein 1 [Homo sapiens] 34 0.069
gi|110611220 ribosome binding protein 1 [Homo sapiens] 34 0.069
gi|194018511 keratin 77 [Homo sapiens] 33 0.12
gi|38570058 hypothetical protein LOC80129 [Homo sapiens] 33 0.15
gi|161702986 ezrin [Homo sapiens] 33 0.15
gi|21614499 ezrin [Homo sapiens] 33 0.15
gi|40254924 leucine rich repeat containing 59 [Homo sapiens] 33 0.15
gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s... 33 0.20
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 33 0.20
gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo sa... 33 0.20
gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo sa... 33 0.20
gi|109150435 ankyrin repeat and zinc finger domain containing 1 ... 33 0.20
gi|109150425 ankyrin repeat and zinc finger domain containing 1 ... 33 0.20
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 32 0.26
gi|27477127 keratin 82 [Homo sapiens] 32 0.26
>gi|21070976 diablo isoform 3 precursor [Homo sapiens]
Length = 195
Score = 386 bits (991), Expect = e-108
Identities = 195/195 (100%), Positives = 195/195 (100%)
Query: 1 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA 60
MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA
Sbjct: 1 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA 60
Query: 61 QAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLS 120
QAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLS
Sbjct: 61 QAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLS 120
Query: 121 EMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEG 180
EMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEG
Sbjct: 121 EMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEG 180
Query: 181 EERAESEQEAYLRED 195
EERAESEQEAYLRED
Sbjct: 181 EERAESEQEAYLRED 195
>gi|9845297 diablo isoform 1 precursor [Homo sapiens]
Length = 239
Score = 365 bits (936), Expect = e-101
Identities = 195/239 (81%), Positives = 195/239 (81%), Gaps = 44/239 (18%)
Query: 1 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA 60
MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA
Sbjct: 1 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA 60
Query: 61 Q--------------------------------------------AVYTLTSLYRQYTSL 76
Q AVYTLTSLYRQYTSL
Sbjct: 61 QKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSL 120
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS
Sbjct: 121 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 180
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED 195
ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED
Sbjct: 181 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED 239
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2081 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2139 RKEAEQEAARRAQAEQAA 2156
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1948 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2054
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2114 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2174 AEQTLRQKAQVEQE 2187
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2085 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2142
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2143 RKEAEQEAARRAQAEQAA 2160
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1952 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2008
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 2009 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2058
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2118 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2177
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2178 AEQTLRQKAQVEQE 2191
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2081 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2139 RKEAEQEAARRAQAEQAA 2156
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1948 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2054
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2114 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2174 AEQTLRQKAQVEQE 2187
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2049 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2106
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2107 RKEAEQEAARRAQAEQAA 2124
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1916 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1972
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 1973 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2022
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2082 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2141
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2142 AEQTLRQKAQVEQE 2155
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2218 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2275
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2276 RKEAEQEAARRAQAEQAA 2293
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 2085 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2141
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 2142 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2191
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2251 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2310
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2311 AEQTLRQKAQVEQE 2324
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2059 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2116
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2117 RKEAEQEAARRAQAEQAA 2134
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1926 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1982
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 1983 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2032
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2092 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2151
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2152 AEQTLRQKAQVEQE 2165
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2067 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2124
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2125 RKEAEQEAARRAQAEQAA 2142
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1934 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1990
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 1991 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2040
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2100 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2159
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2160 AEQTLRQKAQVEQE 2173
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKL-----AEAQIEEL 172
G +E A AA + A++A + A + QVEE +L + AE + A+A E+L
Sbjct: 2108 GEAEAARRAAEE--AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2165
Query: 173 RQKTQEEGEERAESEQEA 190
R++ ++E RA++EQ A
Sbjct: 2166 RKEAEQEAARRAQAEQAA 2183
Score = 32.3 bits (72), Expect = 0.26
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 77 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 136
LG++ S ED + +AE+ + Q L E + A + A +
Sbjct: 1975 LGRIRSNAEDTLRSK---EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Query: 137 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
A ++ +K +VEE +L +AE + A Q QE ++R ++E++A+
Sbjct: 2032 KAALEEVERLKAKVEEARRLRERAEQESARQ-----LQLAQEAAQKRLQAEEKAH 2081
Score = 28.1 bits (61), Expect = 4.9
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 124 AEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAET--------KLAEAQIEELRQK 175
AE Q+ +QA A+ KL+ E + +R+A+ + A+A++E+ ++
Sbjct: 2141 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2200
Query: 176 TQEEGEERAESEQE 189
++ ++A+ EQE
Sbjct: 2201 AEQTLRQKAQVEQE 2214
>gi|197313718 IQ motif containing G [Homo sapiens]
Length = 443
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/131 (27%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 73 YTSLLGKMNSEEEDEVWQVIIGARAE-----MTSKHQEYLKLETTWMTAV-GLSEMAAEA 126
Y SLL ++ E E+++ I AR E + S ++ + ++ W V +E A
Sbjct: 192 YNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANL 251
Query: 127 AYQTGADQASITARNHIQLV--KLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERA 184
Q +A N +LQ+ + + + E L E +IE+LR KT+EE R
Sbjct: 252 KDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVE-EIEKLRMKTEEEA--RT 308
Query: 185 ESEQEAYLRED 195
+E E +LR++
Sbjct: 309 HTEIEMFLRKE 319
>gi|14165288 IQ motif containing G [Homo sapiens]
Length = 443
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/131 (27%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 73 YTSLLGKMNSEEEDEVWQVIIGARAE-----MTSKHQEYLKLETTWMTAV-GLSEMAAEA 126
Y SLL ++ E E+++ I AR E + S ++ + ++ W V +E A
Sbjct: 192 YNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANL 251
Query: 127 AYQTGADQASITARNHIQLV--KLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERA 184
Q +A N +LQ+ + + + E L E +IE+LR KT+EE R
Sbjct: 252 KDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVE-EIEKLRMKTEEEA--RT 308
Query: 185 ESEQEAYLRED 195
+E E +LR++
Sbjct: 309 HTEIEMFLRKE 319
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 35.0 bits (79), Expect = 0.040
Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 74 TSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGAD 133
TS++ KM++ + + +I AE+ ++++E + S AEA YQT +
Sbjct: 316 TSVIVKMDNSRDLNLDGII----AEVKAQYEEVARR----------SRADAEAWYQTKYE 361
Query: 134 QASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLR 193
+ +TA H ++ E+++L+R + AE + + ++ E AE + EA L
Sbjct: 362 EMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLS 421
Query: 194 E 194
+
Sbjct: 422 D 422
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 35.0 bits (79), Expect = 0.040
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 15/132 (11%)
Query: 71 RQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYL-------KLETTWMTAVGLSEMA 123
R+Y L +N EE ++ ++ + YL ++ + S+
Sbjct: 240 REYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAE 299
Query: 124 AEAAYQTGADQASITARNH---IQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEG 180
AEA YQT + ++A+ H +Q K+Q+ ++HQ E + ++Q E L+++
Sbjct: 300 AEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQ-----EIQRLQSQTENLKKQNASLQ 354
Query: 181 EERAESEQEAYL 192
++EQ L
Sbjct: 355 AAITDAEQRGEL 366
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 35.0 bits (79), Expect = 0.040
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 8/133 (6%)
Query: 64 YTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTS---KHQEYLKLETTWMT---AV 117
+ L S + L K+ EEE+E+ ++ ++S + Q+ ++ E M +
Sbjct: 609 HLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 668
Query: 118 GLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQ 177
LS + A+ T AD+ I A L KL+ E Q +KAE E + ++ ++ +
Sbjct: 669 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQ--QKAERASLEQKNRQMLEQLK 726
Query: 178 EEGEERAESEQEA 190
EE E +SEQ A
Sbjct: 727 EEIEASEKSEQAA 739
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 34.3 bits (77), Expect = 0.069
Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 22/140 (15%)
Query: 65 TLTSLYRQYTSLLGKMNS---------EEEDEVWQVIIGARAEMTSKHQEYLKLETTWMT 115
TL + QY S+L + EEE++VW+ +GA E +L+ + +T
Sbjct: 690 TLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEE---------ELQKSRVT 740
Query: 116 AVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQK 175
L E+ + G ++S R H ++ ++E+ H + AE + ++ LRQ
Sbjct: 741 VKHLEEIVEKL---KGELESSDQVREHTSHLEAELEK-HMAAASAECQNYAKEVAGLRQL 796
Query: 176 TQEEGEERAESEQEAYLRED 195
E + ++ EA + D
Sbjct: 797 LLESQSQLDAAKSEAQKQSD 816
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 34.3 bits (77), Expect = 0.069
Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 22/140 (15%)
Query: 65 TLTSLYRQYTSLLGKMNS---------EEEDEVWQVIIGARAEMTSKHQEYLKLETTWMT 115
TL + QY S+L + EEE++VW+ +GA E +L+ + +T
Sbjct: 690 TLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEE---------ELQKSRVT 740
Query: 116 AVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQK 175
L E+ + G ++S R H ++ ++E+ H + AE + ++ LRQ
Sbjct: 741 VKHLEEIVEKL---KGELESSDQVREHTSHLEAELEK-HMAAASAECQNYAKEVAGLRQL 796
Query: 176 TQEEGEERAESEQEAYLRED 195
E + ++ EA + D
Sbjct: 797 LLESQSQLDAAKSEAQKQSD 816
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 33.5 bits (75), Expect = 0.12
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 120 SEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSR-----KAETKLAEAQIEELRQ 174
S+ AEA YQT + ITA H +K E+ +L+R +AE + QIE+++
Sbjct: 349 SKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQS 408
Query: 175 KTQEEGEERAESEQEAY 191
+ E ++ Q+A+
Sbjct: 409 LISDAEERGEQALQDAW 425
>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
Length = 715
Score = 33.1 bits (74), Expect = 0.15
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 96 RAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEV-- 153
R + + Q+YLK + L +MAAE + D + AR QLV+L+ V
Sbjct: 422 RDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLD--VVLARTE-QLVRLESNAVIE 478
Query: 154 -----HQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEA 190
H L RK +T+ + +EL + + E E++A
Sbjct: 479 NKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQA 520
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 33.1 bits (74), Expect = 0.15
Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 19/112 (16%)
Query: 87 EVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLV 146
EV Q+ AR E K E +LET E + ++ + +
Sbjct: 301 EVQQMKAQAREEKHQKQLERQQLET-------------EKKRRETVEREKEQMMREKEEL 347
Query: 147 KLQVEEVHQLSRKAETKLAEA-----QIEELRQKTQEEGEERAESEQEAYLR 193
L++++ + ++KAE +L+E Q+EE R++ QEE ER E+++ A LR
Sbjct: 348 MLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEA-ERLEADRMAALR 398
Score = 28.9 bits (63), Expect = 2.9
Identities = 13/43 (30%), Positives = 25/43 (58%)
Query: 152 EVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE 194
EV Q+ +A + + Q+E + +T+++ E E E+E +RE
Sbjct: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMRE 343
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 33.1 bits (74), Expect = 0.15
Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 19/112 (16%)
Query: 87 EVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLV 146
EV Q+ AR E K E +LET E + ++ + +
Sbjct: 301 EVQQMKAQAREEKHQKQLERQQLET-------------EKKRRETVEREKEQMMREKEEL 347
Query: 147 KLQVEEVHQLSRKAETKLAEA-----QIEELRQKTQEEGEERAESEQEAYLR 193
L++++ + ++KAE +L+E Q+EE R++ QEE ER E+++ A LR
Sbjct: 348 MLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEA-ERLEADRMAALR 398
Score = 28.9 bits (63), Expect = 2.9
Identities = 13/43 (30%), Positives = 25/43 (58%)
Query: 152 EVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE 194
EV Q+ +A + + Q+E + +T+++ E E E+E +RE
Sbjct: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMRE 343
>gi|40254924 leucine rich repeat containing 59 [Homo sapiens]
Length = 307
Score = 33.1 bits (74), Expect = 0.15
Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 11/99 (11%)
Query: 102 KHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLV----------KLQVE 151
K+ ++L L+ + V L+++A + + Q + H++ V +L+VE
Sbjct: 108 KNLKWLDLKDNPLDPV-LAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVE 166
Query: 152 EVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEA 190
+ R+A+ + EAQ ELR++ + E +ER E +A
Sbjct: 167 REAEKKREAKQRAKEAQERELRKREKAEEKERRRKEYDA 205
>gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo
sapiens]
Length = 475
Score = 32.7 bits (73), Expect = 0.20
Identities = 16/47 (34%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
Query: 151 EEVHQLSRKAETKLAEAQIEELRQKTQEEGEERA--ESEQEAYLRED 195
EE+ + +++ + +LA+ +E+LRQ+ +E+ E RA E + L+ED
Sbjct: 69 EELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKED 115
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 32.7 bits (73), Expect = 0.20
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 17/118 (14%)
Query: 78 GKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASI 137
G+M +EE +G + E K +E + + E + Q G + +
Sbjct: 199 GQMGEQEEQ------MGEQEEQMQKQEEQMGEQ---------EEQMRKQEEQMGEQEEQV 243
Query: 138 TARNH-IQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE 194
+ +Q + Q+ + + R+ E ++ E + + L+QK Q E EE+ EQE +RE
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQT-GEQEEQMRE 300
>gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo
sapiens]
Length = 948
Score = 32.7 bits (73), Expect = 0.20
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 149 QVEEVHQLSRKA--ETKLAEAQIEELRQKTQEEGEERAESEQEAYLR 193
Q+EE + +K K AQ+EE R+K Q E E+R + EQE LR
Sbjct: 453 QIEERDRRRQKQLEHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELR 499
Score = 28.9 bits (63), Expect = 2.9
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 55 CAVPIAQAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWM 114
C P Q + ++S+ T ++ EE+ + + I SK +L+ T +
Sbjct: 393 CVSPDTQELADVSSVCTPTTG--SQVEPSEEEHIAKPIKDV-VMANSKKTNFLRSMTALL 449
Query: 115 TAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQ 174
+ E Q Q +ITA+ + K Q+EE + + E +L AQ E Q
Sbjct: 450 DPAQIEERDRRRQKQL-EHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQ 508
Query: 175 KTQEEGEERAESEQE 189
K EE + + ++E
Sbjct: 509 KQYEEDILKQKQKEE 523
>gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo
sapiens]
Length = 914
Score = 32.7 bits (73), Expect = 0.20
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 149 QVEEVHQLSRKA--ETKLAEAQIEELRQKTQEEGEERAESEQEAYLR 193
Q+EE + +K K AQ+EE R+K Q E E+R + EQE LR
Sbjct: 419 QIEERDRRRQKQLEHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELR 465
Score = 28.9 bits (63), Expect = 2.9
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 55 CAVPIAQAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWM 114
C P Q + ++S+ T ++ EE+ + + I SK +L+ T +
Sbjct: 359 CVSPDTQELADVSSVCTPTTG--SQVEPSEEEHIAKPIKDV-VMANSKKTNFLRSMTALL 415
Query: 115 TAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQ 174
+ E Q Q +ITA+ + K Q+EE + + E +L AQ E Q
Sbjct: 416 DPAQIEERDRRRQKQL-EHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQ 474
Query: 175 KTQEEGEERAESEQE 189
K EE + + ++E
Sbjct: 475 KQYEEDILKQKQKEE 489
>gi|109150435 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
Length = 726
Score = 32.7 bits (73), Expect = 0.20
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 152 EVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
E Q +RK E K A Q EE +Q+ QE+ EER EQ +
Sbjct: 611 EARQATRKREQKAARRQREEQQQRQQEQ-EEREREEQRRF 649
>gi|109150425 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
Length = 726
Score = 32.7 bits (73), Expect = 0.20
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 152 EVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAY 191
E Q +RK E K A Q EE +Q+ QE+ EER EQ +
Sbjct: 611 EARQATRKREQKAARRQREEQQQRQQEQ-EEREREEQRRF 649
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 32.3 bits (72), Expect = 0.26
Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
Query: 156 LSRKAE--TKLAEAQIEELRQKTQEEGEERAESEQEAYLRED 195
L +K+E +K+ E +EEL++K +EE E R +E+E L E+
Sbjct: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEE 717
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 32.3 bits (72), Expect = 0.26
Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 24/149 (16%)
Query: 56 AVPIAQAVYTLTSLYRQY----------TSLLGKMNSEEEDEVWQVIIGARAEMTSKHQE 105
A + Q + L SLY + TS++ KM++ E +V +I AE+ +++ +
Sbjct: 243 AEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGII----AEIKAQYDD 298
Query: 106 YLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLA 165
S+ AEA YQ ++ +TA NH ++ + E+ ++++ +
Sbjct: 299 I----------ASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQ 348
Query: 166 EAQIEELRQKTQEEGEERAESEQEAYLRE 194
E + + ++ E AE + EA L +
Sbjct: 349 ETENVKAQRCKLEGAIAEAEQQGEAALND 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.126 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,283,761
Number of Sequences: 37866
Number of extensions: 231449
Number of successful extensions: 3017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 2457
Number of HSP's gapped (non-prelim): 613
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.