Guide to the Human Genome
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Search of human proteins with 210147569

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
         (227 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   457   e-129
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...   437   e-123
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   342   1e-94
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   218   3e-57
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   207   6e-54
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...   161   4e-40
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...   161   4e-40
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]           160   1e-39
gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]           94   7e-20
gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]           89   2e-18
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    86   2e-17
gi|21735415 centromere protein B [Homo sapiens]                        76   3e-14
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    74   8e-14
gi|55956788 nucleolin [Homo sapiens]                                   74   1e-13
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          72   3e-13
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      71   7e-13
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  69   3e-12
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    68   6e-12
gi|4504487 histidine rich calcium binding protein precursor [Hom...    67   1e-11
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               67   1e-11
gi|221219020 NYD-SP11 protein [Homo sapiens]                           67   2e-11
gi|115529449 upstream binding transcription factor, RNA polymera...    67   2e-11
gi|115529451 upstream binding transcription factor, RNA polymera...    67   2e-11
gi|7657671 upstream binding transcription factor, RNA polymerase...    67   2e-11
gi|210032580 SET domain containing 1B [Homo sapiens]                   66   2e-11
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    66   2e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens]              65   4e-11
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       65   5e-11
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       65   5e-11
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        65   5e-11

>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score =  457 bits (1176), Expect = e-129
 Identities = 227/227 (100%), Positives = 227/227 (100%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEE 120
           PSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEE
Sbjct: 61  PSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEE 120

Query: 121 DDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYL 180
           DDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYL
Sbjct: 121 DDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYL 180

Query: 181 MKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
           MKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 181 MKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score =  437 bits (1124), Expect = e-123
 Identities = 227/268 (84%), Positives = 227/268 (84%), Gaps = 41/268 (15%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PSLNKLRK-----------------------------------------QNLKNLKSLDL 79
           PSLNKLRK                                         QNLKNLKSLDL
Sbjct: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120

Query: 80  FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139
           FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
Sbjct: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180

Query: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199
           PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
Sbjct: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240

Query: 200 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
           EEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score =  342 bits (878), Expect = 1e-94
 Identities = 179/220 (81%), Positives = 179/220 (81%), Gaps = 41/220 (18%)

Query: 49  MANVELSSLARLPSLNKLRK---------------------------------------- 68
           MANVELSSLARLPSLNKLRK                                        
Sbjct: 1   MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA 60

Query: 69  -QNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 127
            QNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE
Sbjct: 61  LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 120

Query: 128 DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD 187
           DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD
Sbjct: 121 DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD 180

Query: 188 EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
           EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 181 EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score =  218 bits (555), Expect = 3e-57
 Identities = 125/266 (46%), Positives = 165/266 (62%), Gaps = 56/266 (21%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           M+MK++I+LELRNR+P  V ELVLDNC   +G+IEGL   F  LEFLS+ NV L S++ L
Sbjct: 1   MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60

Query: 61  PSLNKLRK-----------------------------------------QNLKNLKSLDL 79
           P L KL+K                                         + L+ LKSLDL
Sbjct: 61  PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120

Query: 80  FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139
           FNCE+TNL DYRES+F+LL Q+TYLDG+D+ED EAPDS+ E D   +E+++EE E+E   
Sbjct: 121 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDE 180

Query: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199
            +   EEEE +EE+DEDED + DE   E+ E EEE GL         DEED+D+     +
Sbjct: 181 DDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGL---------DEEDEDE-----D 226

Query: 200 EEEEEEEGGLRGEKRKRDAEDDGEEE 225
           E+EEEEEGG +GEKRKR+ +D+GE++
Sbjct: 227 EDEEEEEGG-KGEKRKRETDDEGEDD 251


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score =  207 bits (527), Expect = 6e-54
 Identities = 122/267 (45%), Positives = 165/267 (61%), Gaps = 59/267 (22%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEM ++I+LELRNR+P +V ELVLDN     G++EGL D F+ELEFLS  NV L+S+A L
Sbjct: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60

Query: 61  PSLNKLRK-----------------------------------------QNLKNLKSLDL 79
           P LNKL+K                                         + L+NLKSLDL
Sbjct: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120

Query: 80  FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139
           FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E   +G  DDEEE+E+E   
Sbjct: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179

Query: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199
            E  +  E+EE+E++E+E E+ED +G    E E+E G +     E+ DEED++   E GE
Sbjct: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230

Query: 200 EEEEEEEGGLRGEKRKRDAEDDGEEED 226
           EE        RG+KRKR+ ED+GE++D
Sbjct: 231 EE--------RGQKRKREPEDEGEDDD 249


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  161 bits (408), Expect = 4e-40
 Identities = 107/256 (41%), Positives = 139/256 (54%), Gaps = 70/256 (27%)

Query: 15  SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRK------ 68
           S   V E VLDNC   + +IE L   F  LEFL + NV L S++ LP L KL+K      
Sbjct: 35  SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94

Query: 69  -----------------------------------QNLKNLKSLDLFNCEITNLEDYRES 93
                                              + L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95  RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154

Query: 94  IFELLQQITYLDGFDQEDNEAPDSE--------EEDDEDGDEDDEEEEENEAGPPEGYEE 145
           +F+LL Q+T LD +D ED EAPDS+        EE+DE+G+  DE++ ENE G      E
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGE--DEKDXENEDG------E 206

Query: 146 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 205
           EEE +EEEDEDED + D+   E+ E EEE GL        +DE+D+D    E E+EEEEE
Sbjct: 207 EEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD-------KDEDDED----EDEDEEEEE 255

Query: 206 EGGLRGEKRKRDAEDD 221
            G  +GE RKR+ +D+
Sbjct: 256 SG--KGENRKRETDDE 269


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  161 bits (408), Expect = 4e-40
 Identities = 107/256 (41%), Positives = 139/256 (54%), Gaps = 70/256 (27%)

Query: 15  SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRK------ 68
           S   V E VLDNC   + +IE L   F  LEFL + NV L S++ LP L KL+K      
Sbjct: 35  SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94

Query: 69  -----------------------------------QNLKNLKSLDLFNCEITNLEDYRES 93
                                              + L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95  RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154

Query: 94  IFELLQQITYLDGFDQEDNEAPDSE--------EEDDEDGDEDDEEEEENEAGPPEGYEE 145
           +F+LL Q+T LD +D ED EAPDS+        EE+DE+G+  DE++ ENE G      E
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGE--DEKDXENEDG------E 206

Query: 146 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 205
           EEE +EEEDEDED + D+   E+ E EEE GL        +DE+D+D    E E+EEEEE
Sbjct: 207 EEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD-------KDEDDED----EDEDEEEEE 255

Query: 206 EGGLRGEKRKRDAEDD 221
            G  +GE RKR+ +D+
Sbjct: 256 SG--KGENRKRETDDE 269


>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score =  160 bits (404), Expect = 1e-39
 Identities = 107/253 (42%), Positives = 140/253 (55%), Gaps = 57/253 (22%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEM ++I+ ELRNR+P +V EL LDN     G++E L D F+ELEFLS  N  L+S++ L
Sbjct: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60

Query: 61  PSLNKLRK--------------------------------------QNLKNLKSLDLFNC 82
           P L KLRK                                      + L+NLKSLDLFNC
Sbjct: 61  PKL-KLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNC 119

Query: 83  EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG 142
           E+TNL DY E++F+LL Q+TYLD    +  EAP S+ ED  +G  DDEEE E+E    E 
Sbjct: 120 EVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDDEEEGEHEEEYDED 178

Query: 143 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 202
            +  E+EE EE+E+E E+ED +G     G+EE            DEE  +D   +GEE+E
Sbjct: 179 AQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEEGYNDGEVDGEEDE 221

Query: 203 EEEEGGLRGEKRK 215
           EE     RG+KRK
Sbjct: 222 EELGEEERGQKRK 234



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 184 EIQDEEDDDDYVEEGEEEEE-EEEGGLRGEKRKRDAEDDGEEED 226
           +I+D  +  D  EEGE EEE +E+  +  ++   + E++GEEED
Sbjct: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEED 198


>gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]
          Length = 450

 Score = 94.4 bits (233), Expect = 7e-20
 Identities = 67/185 (36%), Positives = 87/185 (47%), Gaps = 47/185 (25%)

Query: 15  SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRK------ 68
           S   V E VLDNC   + +IE L   F  LEFL + NV L S++ LP L KL+K      
Sbjct: 35  SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94

Query: 69  -----------------------------------QNLKNLKSLDLFNCEITNLEDYRES 93
                                              + L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95  RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154

Query: 94  IFELLQQITYLDGFDQEDNEAPDSEEE--DDEDGDEDDEEEE----ENEAGPPEGYEEEE 147
           +F+LL Q+T LD +D ED EAPDS+ +   D  G E           + A PPE     +
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQLLADPWGKEYHTNNAPLLLRSPAWPPEPSIRPQ 214

Query: 148 EEEEE 152
           E++ E
Sbjct: 215 EQDYE 219


>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
          Length = 131

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 53/131 (40%), Positives = 69/131 (52%), Gaps = 41/131 (31%)

Query: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
           MEM K I+LELRNR+P +V EL LDN     G++EGL D F+ELE L+  N+ L+S+A L
Sbjct: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60

Query: 61  PSLNKLRK-----------------------------------------QNLKNLKSLDL 79
           P LNKL+K                                         + L+NL+SLDL
Sbjct: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120

Query: 80  FNCEITNLEDY 90
           F CE+TNL +Y
Sbjct: 121 FTCEVTNLNNY 131


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 51/126 (40%), Positives = 76/126 (60%), Gaps = 6/126 (4%)

Query: 104 LDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
           ++G + E+ +    EEE++ +G+E++ E EE E    EG EEE E + EE+ +E E E+E
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG---EGEEEEGEGKGEEEGEEGEGEEE 870

Query: 164 AGSELGEGEEEVGLSYLMKE---EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED 220
                GEGEEE G     +E   E ++EE + +  EEGE E EEEEG  +GE+   + E 
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930

Query: 221 DGEEED 226
           +GEEE+
Sbjct: 931 EGEEEE 936



 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 55/138 (39%), Positives = 74/138 (53%), Gaps = 16/138 (11%)

Query: 105  DGFDQEDNEAPDSEEEDDEDGDEDDEE-----EEENEAGPPEGYEEEEEEEEEEDEDEDE 159
            +G  +E+ E    EEE +  G+E+ EE     EEE   G  E  E E EEEE E E E+E
Sbjct: 901  EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960

Query: 160  DEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE-----------EEEEEGG 208
            + +  G E GEGE E G     +EE + E ++++  EEGEEE           EEEEEG 
Sbjct: 961  EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020

Query: 209  LRGEKRKRDAEDDGEEED 226
            + GE    + E +GEEE+
Sbjct: 1021 VEGEVEGEEGEGEGEEEE 1038



 Score = 84.7 bits (208), Expect = 6e-17
 Identities = 55/125 (44%), Positives = 73/125 (58%), Gaps = 9/125 (7%)

Query: 110  EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED--EAGSE 167
            ED E    EEE + +G+E++ E E  E G  EG E E E EEEE E E E+E+  E G E
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001

Query: 168  LGEGEEEVGLSYLMKEE--IQDEEDDDDYVEEGEEEEEEEEGGLR-----GEKRKRDAED 220
             GEGEEE       +EE  ++ E + ++   EGEEEE EEEG  R     GE+ +R+ E+
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061

Query: 221  DGEEE 225
            + EEE
Sbjct: 1062 EEEEE 1066



 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 53/118 (44%), Positives = 68/118 (57%), Gaps = 5/118 (4%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE-EEEEDEDEDEDEDEAGSEL 168
           E+ E    EEE + +G+E+ E E E E G  EG EE E E EEEE E + E+E E G   
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE-- 929

Query: 169 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
           GEGEEE G       E + EE++ ++  EGEEEE E EG   GE    + E +GEEE+
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEW--EGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985



 Score = 81.3 bits (199), Expect = 6e-16
 Identities = 51/122 (41%), Positives = 70/122 (57%), Gaps = 11/122 (9%)

Query: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164
           +G  +E+ E    EEE + +G+E+ E E E E G  +G EE EE E E +E+E E E E 
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 224
           G   GEGEEE G     + E ++EE + +  EEGE E EE EG    E  + + E +GEE
Sbjct: 944 GE--GEGEEEEG-----EWEGEEEEGEGEGEEEGEGEGEEGEG----EGEEEEGEGEGEE 992

Query: 225 ED 226
           E+
Sbjct: 993 EE 994



 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 52/118 (44%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 168
           +E+ +  + EEE+ E   E+ EE  E E G  E  + E EEEEEE E E+E E E   E 
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE-EGEGEEEE 846

Query: 169 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
           GEGEEE G      EE  +E + ++  EEGE E EEEEG   GE+   + E +GEEE+
Sbjct: 847 GEGEEEEGEG--KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE---EGEGEGEEEE 899



 Score = 78.2 bits (191), Expect = 5e-15
 Identities = 52/132 (39%), Positives = 73/132 (55%), Gaps = 11/132 (8%)

Query: 105  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYE-------EEEEEEEEEDEDE 157
            +G  +E+    + EEE + +G+E++ E E  E G  EG E       EEE EE E + +E
Sbjct: 875  EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934

Query: 158  DEDEDEAGSELGEGEEEVGLSYLMKE--EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 215
            +E E E     GEGEEE G     +E  E + EE+ +   EEGE E EEEEG   GE  +
Sbjct: 935  EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG--EGEGEE 992

Query: 216  RDAEDDGEEEDD 227
             + E++GEEE +
Sbjct: 993  EEGEEEGEEEGE 1004



 Score = 77.8 bits (190), Expect = 7e-15
 Identities = 56/120 (46%), Positives = 67/120 (55%), Gaps = 13/120 (10%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEE---EEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 166
           E+ E    EEE +  G+E+ EE   EEE E G  EG EEEE E E E+E E E E+E G 
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG-EEEEGEGEGEEEGEGEGEEEEGE 901

Query: 167 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
             GEGEEE        EE + E   ++  EEGE E EEEEG   GE    D E +GEEE+
Sbjct: 902 --GEGEEE---GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE----DGEGEGEEEE 952



 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 53/131 (40%), Positives = 71/131 (54%), Gaps = 23/131 (17%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEA--------GPPEGYEEEE---EEEEEEDED 156
           +++  E    EE+ +E+GD+ + EEEE E         G  EG E EE   E EEEE+E 
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833

Query: 157 EDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKR 216
           E E+E+      GEGEEE G      EE + E   ++  EEGE EEE EEG   GE  + 
Sbjct: 834 EGEEEE------GEGEEEEGEG----EEEEGEGKGEEEGEEGEGEEEGEEG--EGEGEEE 881

Query: 217 DAEDDGEEEDD 227
           + E +GEEE +
Sbjct: 882 EGEGEGEEEGE 892



 Score = 75.5 bits (184), Expect = 4e-14
 Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 18/129 (13%)

Query: 105  DGFDQEDNEAPDSEEE-DDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
            +G ++ + E  + E E ++E+G+ + EEEE  E G  EG  EEE E E E+E+E E E E
Sbjct: 965  EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024

Query: 164  AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE--------EEEEEEEGGLRGEKRK 215
               E GEGE E         E + EE+ ++  +EGE        EEEEEEEG  +    +
Sbjct: 1025 VEGEEGEGEGE---------EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075

Query: 216  RDAEDDGEE 224
             +   DGEE
Sbjct: 1076 ENERQDGEE 1084



 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 57/160 (35%), Positives = 84/160 (52%), Gaps = 17/160 (10%)

Query: 83  EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDS--EEE----DDEDGDEDDEEEEENE 136
           E+   E++++   E  +Q     G  +E N+  +   EEE    ++E+GD ++EEE+E E
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754

Query: 137 AGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE--------LGEGEEEVGLSYLMKEEIQDE 188
            G  EG  EE E E E++E E + E+ AG E         GEGEEE       ++E   E
Sbjct: 755 -GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813

Query: 189 EDDDDYVE-EGEEEEEEEEG-GLRGEKRKRDAEDDGEEED 226
            +  +  E +GE EEEEEEG G   E    + E +GEEE+
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853



 Score = 71.6 bits (174), Expect = 5e-13
 Identities = 47/123 (38%), Positives = 66/123 (53%), Gaps = 10/123 (8%)

Query: 108 DQEDNEAPDSE---EEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164
           DQ + E  ++E   EE +E G+ +  E EE +    E  EE E EEEE + +E+E E E 
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 224
               G+GEEE        EE + EE+ ++   EGEEEE E EG   GE    + E +GE 
Sbjct: 852 EEGEGKGEEE-------GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG 904

Query: 225 EDD 227
           E++
Sbjct: 905 EEE 907



 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 11/121 (9%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEE-ENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 166
           ++E+ E    EE ++ +G+E+ EE E E E    EG  EEE E E E+E+ + + +E G 
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909

Query: 167 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG-GLRGEKRKRDAEDDGEEE 225
             GEGEEE G       E + EE+ ++   EGEEEE E EG    GE  + + E +GEEE
Sbjct: 910 --GEGEEEEG-------EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960

Query: 226 D 226
           +
Sbjct: 961 E 961



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 11/130 (8%)

Query: 108 DQEDNEAPDSEEEDDEDGDE--DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED--- 162
           D+E+ E  + E +++ +G+E   + E+EE E    E   +EE+ EEE D+ E E+E+   
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803

Query: 163 -----EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD 217
                E G E+  GE E G     +EE + E ++++   E EE E EEE G  G+  +  
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG-EGKGEEEG 862

Query: 218 AEDDGEEEDD 227
            E +GEEE +
Sbjct: 863 EEGEGEEEGE 872



 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 47/129 (36%), Positives = 66/129 (51%), Gaps = 12/129 (9%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE---EEEEDEDEDEDEDEAGS 166
           E  E  + EE + E   E+ E ++E  AG  E  EEE ++   EEEE E   E+++E G 
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813

Query: 167 -ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL--------RGEKRKRD 217
            E GE EE  G     +EE + EE++ +  EE  E EEEE  G          GE+   +
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873

Query: 218 AEDDGEEED 226
            E +GEEE+
Sbjct: 874 GEGEGEEEE 882



 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 12/126 (9%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG-- 165
           ++E  E      E +  G+ + E  E+ E    +G E+E++E E+  + E   E E G  
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732

Query: 166 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE----EEEEEEEGGLRGEKRKRDAEDD 221
            E GEGEEE G      +  ++EE + +  EEGE    E E E+E G R ++ +   E+ 
Sbjct: 733 EEHGEGEEEEG------DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786

Query: 222 GEEEDD 227
           GEEE D
Sbjct: 787 GEEEGD 792



 Score = 60.8 bits (146), Expect = 9e-10
 Identities = 42/130 (32%), Positives = 70/130 (53%), Gaps = 27/130 (20%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEE--EEEEEEEDEDEDEDEDEAG 165
           ++E+ +  D EE++ ++ ++  ++E   E    EG EEE  E EEEE D +E+E+++  G
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEM--EEGGEEEHGEGEEEEGDREEEEEKEGEG 755

Query: 166 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE--------EEGGLRGEKRKRD 217
            E GEGEE           ++ E +     EEGE ++EE        EE G +GE  + +
Sbjct: 756 KEEGEGEE-----------VEGEREK----EEGERKKEERAGKEEKGEEEGDQGEGEEEE 800

Query: 218 AEDDGEEEDD 227
            E  GEE+++
Sbjct: 801 TEGRGEEKEE 810



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 57/243 (23%), Positives = 96/243 (39%), Gaps = 39/243 (16%)

Query: 17  EEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLA-RLPSLNKLRKQNLKNLK 75
           E   E  +DN    +  +E L +T   L    + ++  +  + +L  + K +KQ      
Sbjct: 477 EMTKEAEIDN----SSTVESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTIGEL 532

Query: 76  SLDLFNCEITNLEDYRE----------------SIFELLQQITYLDGFDQEDNEAPDSEE 119
           + D    E  + ++Y E                 IF + Q  T ++ F  E+ E P+ +E
Sbjct: 533 TQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIF-MTQPATTIEAFSDEEVEIPEEKE 591

Query: 120 --EDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVG- 176
             ED +    +++E E NE         +E+ E   D+  D+ E   G     GE E G 
Sbjct: 592 GAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGP 651

Query: 177 ---------LSYLMKEEIQDEEDDDDYVEEGEEE-----EEEEEGGLRGEKRKRDAEDDG 222
                          E  QDEE +    ++G  E     E E+E   + E +KRD E+  
Sbjct: 652 EGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE 711

Query: 223 EEE 225
           ++E
Sbjct: 712 QKE 714



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 13/119 (10%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
           D   ++A  SE +    G+ +D  E   +    EG    E  ++EE E  ++D+     E
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687

Query: 168 L-GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 225
             GEGE+E+      KEE +  + ++      +E++E E+G    ++R ++ E+ GEEE
Sbjct: 688 RPGEGEKELA----EKEEWKKRDGEE------QEQKEREQG--HQKERNQEMEEGGEEE 734


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)

Query: 102 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 157
           T L    +E+ E  + EEE++ +G+E++E  EEEE E G  E  G EEE EEE + D DE
Sbjct: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458

Query: 158 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 198
           +E+EDE  S  G       +G  E G S   Y  +EE Q          E+ D D  EE 
Sbjct: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518

Query: 199 EEEEEEEEGGLRGEKRKRDAEDDGEEED 226
           +EEE++E           D +DD +EED
Sbjct: 519 DEEEDDE-----------DEDDDDDEED 535



 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)

Query: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 162
           +G ++E+ E  + EEE + + +E++ EEEE E G  E  G EEE EEE + D DE+E+ED
Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463

Query: 163 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 203
           E  S  G       +G  E G S   Y  +EE Q          E+ D D  EE +EEE+
Sbjct: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523

Query: 204 EEEGGLRGEKRKRDAEDDGEEEDD 227
           +E+            EDD ++E+D
Sbjct: 524 DED------------EDDDDDEED 535



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)

Query: 106 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 140
           G  +E  E  + EEE D D DE++EE+EE+               EAG            
Sbjct: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496

Query: 141 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
                   EG E+ + + EEED++E++DEDE   +  E  +EV
Sbjct: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)

Query: 103 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 140
           +L+G +  D+  E  D EEEDDED D+DD+EE+ +E   P
Sbjct: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 43/97 (44%), Positives = 62/97 (63%), Gaps = 12/97 (12%)

Query: 116 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
           D EEE++E+ +E++EEEEE E    E +EEEEE+EEE  E+E+E+E+E   E  E E E+
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEE----EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942

Query: 176 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
                   E ++EE+D++  EE EE E+ E G   GE
Sbjct: 943 --------EEEEEEEDEEEEEELEEVEDLEFGTAGGE 971



 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 45/99 (45%), Positives = 59/99 (59%), Gaps = 20/99 (20%)

Query: 115 PDSEEED-------DEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
           P + EED         D +E++EEEEE E       EEEEEEEEE+ E+E+EDE+E   E
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEE-------EEEEEEEEEDFEEEEEDEEEYFEE 923

Query: 168 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
             E EEE       +EE ++EE + +  EE E+EEEEEE
Sbjct: 924 EEEEEEE------FEEEFEEEEGELEEEEEEEDEEEEEE 956



 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 35/76 (46%), Positives = 50/76 (65%), Gaps = 1/76 (1%)

Query: 146 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY-VEEGEEEEEE 204
           +EEEEEEE+E+E+E+E+E   E  E EEE    Y  +EE ++EE ++++  EEGE EEEE
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 205 EEGGLRGEKRKRDAED 220
           EE     E+   + ED
Sbjct: 947 EEEDEEEEEELEEVED 962



 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 33/84 (39%), Positives = 48/84 (57%), Gaps = 22/84 (26%)

Query: 144 EEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 203
           EEEEEEEEEE+E+E+E+E+E                   E+ ++EE+D+   EE  EEEE
Sbjct: 888 EEEEEEEEEEEEEEEEEEEE-------------------EDFEEEEEDE---EEYFEEEE 925

Query: 204 EEEGGLRGEKRKRDAEDDGEEEDD 227
           EEE     E  + + E + EEE++
Sbjct: 926 EEEEEFEEEFEEEEGELEEEEEEE 949



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 10/116 (8%)

Query: 108  DQEDNEAPDSEEEDDEDGDEDDEEEEEN---EAGPPEGY---EEEEEEEEEEDEDEDEDE 161
            ++E+ E  + EEED+E+  E++EEEEE    E    EG    EEEEE+EEEE+E E+ ++
Sbjct: 903  EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962

Query: 162  DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE----EEEEGGLRGEK 213
             E G+  GE EE       +   +   E       E E E     E EE G   E+
Sbjct: 963  LEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEE-DEDEDEDEDE 163
           + F++E+ +  +  EE++E+ +E +EE EE E    E  EEE+EEEEEE +E ED +   
Sbjct: 908 EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT 967

Query: 164 AGSELGEG 171
           AG E+ EG
Sbjct: 968 AGGEVEEG 975



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 18/56 (32%), Positives = 35/56 (62%)

Query: 172 EEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
           EE++ +  +   + ++EE++++  EE EEEEEEE+     E  +   E++ EEE++
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930



 Score = 30.8 bits (68), Expect = 0.99
 Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 6/63 (9%)

Query: 108  DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
            ++E +  P   EE+ EDG +  +   E  A      EEE E E E +  +++++D+  + 
Sbjct: 1055 EEEPSAPPTLLEEETEDGSDKVQPPPETPA------EEEMETETEAEALQEKEQDDTAAM 1108

Query: 168  LGE 170
            L +
Sbjct: 1109 LAD 1111



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 116  DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEE------EDEDEDEDEDEAGSELG 169
            + E E    G    E  EE  + PP   EEE E+  +      E   E+E E E  +E  
Sbjct: 1038 EREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097

Query: 170  EGEEEVGLSYLMKEEIQDEEDDD 192
            + +E+   + ++ + I    DD+
Sbjct: 1098 QEKEQDDTAAMLADFIDCPPDDE 1120



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 29/97 (29%), Positives = 39/97 (40%), Gaps = 19/97 (19%)

Query: 113  EAPDSEEEDDEDG------------DEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDED 160
            E P +EEE   D              E + E E   AGPP   +E  EEE        E+
Sbjct: 1010 EEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPP--QELVEEEPSAPPTLLEE 1067

Query: 161  EDEAGSELGEGEEEVGLSYLMK-----EEIQDEEDDD 192
            E E GS+  +   E      M+     E +Q++E DD
Sbjct: 1068 ETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 41/135 (30%), Positives = 70/135 (51%), Gaps = 25/135 (18%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
           +  D E  D  EED+ED +++DE+E+E E    +        E+E+DED+++DED+   E
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202

Query: 168 LGEGEEE---------------VGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
             + EEE               V +      E +DEE+DD+  ++ ++E++E++      
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD------ 256

Query: 213 KRKRDAEDDGEEEDD 227
               D EDD EEE++
Sbjct: 257 ----DDEDDEEEEEE 267



 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 40/138 (28%), Positives = 77/138 (55%), Gaps = 30/138 (21%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEE----ENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
           D+E+++  + +EEDDED DED++E E    +  A  P   +E++E++E++++D+D++ED+
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDD 205

Query: 164 AGSELGEGEEEVGLSYLM--------------KEEIQDEEDDDDYVEEGEEEEEEEEGGL 209
           +  E  E     G                   +EE  ++EDDDD  +E +E++++E+   
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD--DEDDEDDDDED--- 260

Query: 210 RGEKRKRDAEDDGEEEDD 227
                  D E++ EEE++
Sbjct: 261 -------DEEEEEEEEEE 271



 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 30/128 (23%)

Query: 115 PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-------AGSE 167
           P    ++ ++  ++D +EEE++       + EE+EE++EDEDEDEDE E       A + 
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDD-------DSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182

Query: 168 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE--------KRKRDAE 219
             E E++        E+ +D+EDDDD  E+  EEE  E    +G+        K K  AE
Sbjct: 183 ASEDEDD--------EDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234

Query: 220 DDGEEEDD 227
           D+ EEEDD
Sbjct: 235 DEDEEEDD 242



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/129 (30%), Positives = 69/129 (53%), Gaps = 29/129 (22%)

Query: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE------EEEEEEDEDEDEDED 162
           +++++  D ++EDD+D +EDD EEE  E  P +G +  +      +   E++++E++DED
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244

Query: 163 EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE------GGLRGEKRKR 216
           E                   ++ +D+EDDDD  +E EEEEEEEE      G  + E  K+
Sbjct: 245 ED-----------------DDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287

Query: 217 DAEDDGEEE 225
            A  + +++
Sbjct: 288 KAAPEAKKQ 296



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 24/109 (22%)

Query: 105 DGFDQEDNEAPDSEEE------------------------DDEDGDEDDEEEEENEAGPP 140
           D  D +D+E  DSEEE                        +DED +EDDE+E++++    
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD 253

Query: 141 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 189
           E  ++E++EEEEE+E+E+  ++  G    E  ++       K++++  E
Sbjct: 254 EDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302



 Score = 31.6 bits (70), Expect = 0.58
 Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 3/40 (7%)

Query: 129 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 168
           ++ + +  A PP+   E EE+ E+E+  EDE++D +G E+
Sbjct: 10  NQGDPKKMAPPPK---EVEEDSEDEEMSEDEEDDSSGEEV 46



 Score = 28.1 bits (61), Expect = 6.4
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 138 GPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGE 170
           G P+      +E EE+ EDE+  EDE     GE
Sbjct: 12  GDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGE 44


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 47/123 (38%), Positives = 64/123 (52%), Gaps = 23/123 (18%)

Query: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164
           DG +  D +  D  EE  ED DE  +E+EE+E    EG  EEEEE EEEDED+DED    
Sbjct: 94  DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE----EGDREEEEEIEEEDEDDDED---- 145

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 224
               GE  E+        EE ++EE+++   EE EEE E+ +      +  +D E D   
Sbjct: 146 ----GEDVED--------EEEEEEEEEE---EEEEEENEDHQMNCHNTRIMQDTEKDDNN 190

Query: 225 EDD 227
            D+
Sbjct: 191 NDE 193



 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 169
           EDN+ P  E+E+DE+GD ++EEE E E    +  E+ E+ E+EE+E+E+E+E+E   E  
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169

Query: 170 EGEEEVGLSYLMKEEIQDEEDDDDY 194
           + +     + +M++  +D+ ++D+Y
Sbjct: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 36/110 (32%), Positives = 51/110 (46%), Gaps = 35/110 (31%)

Query: 118 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 177
           +E DD DG ED +E+EE+E            EE  ED DE  DEDE              
Sbjct: 88  DECDDSDGTEDMDEKEEDEG-----------EEYSEDNDEPGDEDE-------------- 122

Query: 178 SYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
                     E+++ D  EE E EEE+E+    GE  + + E++ EEE++
Sbjct: 123 ----------EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 8/122 (6%)

Query: 88  EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG----- 142
           E+  E   E  ++I   D  D ED E  D E+E++E+ +E++EEEEE             
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGE--DVEDEEEEEEEEEEEEEEEENEDHQMNCHNTR 179

Query: 143 -YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 201
             ++ E+++   DE ++ DE  A S L  G+     +Y  + E +   +  + +E+  ++
Sbjct: 180 IMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDK 239

Query: 202 EE 203
            E
Sbjct: 240 NE 241



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%)

Query: 127 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 185
           +D + +E      P   + +    +E +D D  ED DE                  KEE 
Sbjct: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105

Query: 186 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
           + EE  +D  E G+E+EE+ E G R E+ + + ED+ ++ED
Sbjct: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 36/136 (26%), Positives = 74/136 (54%), Gaps = 15/136 (11%)

Query: 49  MANVELSSLARLPSLNKLRKQNLKNLKSLDLFN-CEITNLEDYRESIFELLQQITYLDGF 107
           + N   + L ++  + K+R+Q ++ L+ L +FN  E +NL  Y                 
Sbjct: 177 ITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRG-------------- 222

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
            Q+D +  D E  D+++G  +  EE E++    +G +E++E+++++D+D+D+D+DE   +
Sbjct: 223 KQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDED 282

Query: 168 LGEGEEEVGLSYLMKE 183
             +GEEE    Y +++
Sbjct: 283 EEDGEEENQKRYYLRQ 298



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 21/104 (20%)

Query: 123 EDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMK 182
           ED    +E EE N      G +++ +  +EE  D  E   E+                  
Sbjct: 203 EDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESS----------------- 245

Query: 183 EEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
           EE +D+E +DD    GE+E++E++     +    D EDD +EED
Sbjct: 246 EEGEDQEHEDD----GEDEDDEDDDDDDDDDDDDDDEDDEDEED 285



 Score = 34.7 bits (78), Expect = 0.069
 Identities = 18/77 (23%), Positives = 39/77 (50%)

Query: 151 EEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLR 210
           E ED     + +E+   +    ++  +    +E   ++E   +  EEGE++E E++G   
Sbjct: 201 ELEDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDE 260

Query: 211 GEKRKRDAEDDGEEEDD 227
            ++   D +DD +++DD
Sbjct: 261 DDEDDDDDDDDDDDDDD 277


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 14/132 (10%)

Query: 108 DQEDNEAPDSEEEDDEDGD------------EDDEEEEENEAGPPEGYEEEEEEEEEEDE 155
           D  ++EA +SEEE +++G+            EDD+EEEE E    +  +   +    +D+
Sbjct: 3   DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62

Query: 156 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD--EEDDDDYVEEGEEEEEEEEGGLRGEK 213
           DEDE E++ GS+ G+ E++VG     +    D  E+DD D +EE    + +     R  K
Sbjct: 63  DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122

Query: 214 RKRDAEDDGEEE 225
           +  D EDD EEE
Sbjct: 123 KMSDDEDDDEEE 134



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 14/112 (12%)

Query: 116 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
           D  E + E+ +E+  +E E      + + EEE+++EEE+E+  +D+DE G+         
Sbjct: 3   DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN--------- 53

Query: 176 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
                +K  I D++D+D+  E+   +  + E  +  +KRKR + DD  E+DD
Sbjct: 54  -----LKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 14/123 (11%)

Query: 107 FDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-- 163
           + +E++E     EE  +DG+ E+ +E  E    PPE  EE++EE + +D   D+D     
Sbjct: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194

Query: 164 -----------AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
                        + L E +E  G+ +   E  +  E D++  EE E E++E EG +R  
Sbjct: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254

Query: 213 KRK 215
            +K
Sbjct: 255 PKK 257



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 8/68 (11%)

Query: 147 EEEEEEEDEDEDEDEDEAGSELGEGE--------EEVGLSYLMKEEIQDEEDDDDYVEEG 198
           EE +EE + DE EDE++ G EL +          +  GL  L K+     E   + + + 
Sbjct: 494 EEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDS 553

Query: 199 EEEEEEEE 206
            +  E E+
Sbjct: 554 YQRHETEQ 561


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 36/95 (37%), Positives = 54/95 (56%)

Query: 131  EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEED 190
            E+ E++   PE  EEEEEEEEEE+E+E+ +E+E G  + +  +        + EI  E++
Sbjct: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400

Query: 191  DDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 225
            D   +++ EEEEEE+E     E    D EDD   E
Sbjct: 1401 DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHME 1435



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 30/92 (32%), Positives = 50/92 (54%)

Query: 113  EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGE 172
            E  + EEE++E+ +E++ EEEE      +  +  + +E+EE E   E ED A  +  E E
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411

Query: 173  EEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 204
            EE        E+   +++DD ++E  E E+EE
Sbjct: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEE 1443



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/47 (53%), Positives = 36/47 (76%), Gaps = 7/47 (14%)

Query: 117  SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
            S+E  +E+ +E+DEEEEE E       EEEEE+EEEE+E+E+E+E+E
Sbjct: 1065 SKESSEEEEEEEDEEEEEEE-------EEEEEDEEEEEEEEEEEEEE 1104



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 25/51 (49%), Positives = 37/51 (72%), Gaps = 9/51 (17%)

Query: 116  DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 166
            +S EE++E+ DE++EEEEE         EEEE+EEEEE+E+E+E+E+   S
Sbjct: 1067 ESSEEEEEEEDEEEEEEEE---------EEEEDEEEEEEEEEEEEEENIQS 1108



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 34/115 (29%), Positives = 63/115 (54%), Gaps = 21/115 (18%)

Query: 109  QEDNEAPDSEEEDDEDGDEDDEEEE--ENEAG-----PPEGYEEEEEEEEE--------- 152
            ++D   P+ EEE++E+ +E++EEEE  E E G      P+G + +E+EE E         
Sbjct: 1344 EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSA 1403

Query: 153  ----EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 203
                 +E+E+EDE+ + +E  + ++E   S++   E++ EE   +  +E  E +E
Sbjct: 1404 RLDDHEEEEEEDEEPSHNEDHDADDEDD-SHMESAEVEKEELPRESFKEVLENQE 1457



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 5/127 (3%)

Query: 106  GFDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEE----DEDEDED 160
            GF       P++  E DE    E+ +E  E +  P     EEE +E  E     E+   +
Sbjct: 1268 GFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRRE 1327

Query: 161  EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED 220
            E  A         E     L+K E ++EE++++  EE EEE EEEEGG   EK    A+ 
Sbjct: 1328 ETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKS 1387

Query: 221  DGEEEDD 227
              +EE +
Sbjct: 1388 QEKEEPE 1394



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 33/163 (20%)

Query: 54   LSSLARLPSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFE---LLQQITYLDGFDQE 110
            LS + +L + ++  + +  +L+   +        E+ RE+  E   L++Q +  +  +QE
Sbjct: 965  LSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQE 1024

Query: 111  -------DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
                     ++P   +  ++     +      E G      +E  EEEEE+EDE+E+E+E
Sbjct: 1025 ILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEE 1084

Query: 164  AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
                                   +EE++D+  EE EEEEEEEE
Sbjct: 1085 -----------------------EEEEEDEEEEEEEEEEEEEE 1104



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 10/85 (11%)

Query: 105  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164
            DG   ++ E P+   E ++    DD EEEE         EE+EE    ED D D DED++
Sbjct: 1383 DGAKSQEKEEPEISTEKEDSARLDDHEEEE---------EEDEEPSHNEDHDAD-DEDDS 1432

Query: 165  GSELGEGEEEVGLSYLMKEEIQDEE 189
              E  E E+E       KE ++++E
Sbjct: 1433 HMESAEVEKEELPRESFKEVLENQE 1457



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 25/67 (37%), Positives = 36/67 (53%)

Query: 109  QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 168
            Q  N+   S E     G+     E   E+   E  EE+EEEEEEE+E+E+++E+E   E 
Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099

Query: 169  GEGEEEV 175
             E EE +
Sbjct: 1100 EEEEENI 1106



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 22/123 (17%)

Query: 14   RSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKQNLKN 73
            R  E+  E +++   C   E         E E LS       S A++ S NK        
Sbjct: 1002 REAEKEAERLMEQASCWEKE---------EQEILSTRANSRQSPAKVQSKNKY------- 1045

Query: 74   LKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEE 133
                 L + E   +   R  + EL ++ +  +  ++ED E  + EEE++ED +E++EEEE
Sbjct: 1046 -----LHSPESRPVTGERGQLLELSKESSEEEE-EEEDEEEEEEEEEEEEDEEEEEEEEE 1099

Query: 134  ENE 136
            E E
Sbjct: 1100 EEE 1102



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 11/118 (9%)

Query: 109  QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 168
            +E+ EA    E   E     ++EE+E  +      +   + + +       +      E 
Sbjct: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058

Query: 169  GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
            G+      L  L KE  ++EE+++D     EEEEEEEE     E+ + + E++ EEE+
Sbjct: 1059 GQ------LLELSKESSEEEEEEED-----EEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 14/34 (41%), Positives = 27/34 (79%), Gaps = 1/34 (2%)

Query: 108  DQEDNEAPDSEEEDDEDGDEDDEEEEEN-EAGPP 140
            ++E+ E  + EE+++E+ +E++EEEEEN ++ PP
Sbjct: 1078 EEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111



 Score = 35.0 bits (79), Expect = 0.053
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 9/132 (6%)

Query: 81   NCEITNLEDYRESIFELLQ-QITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139
            + E+   E  RES  E+L+ Q T+LD   Q  +  P+   +   D       E +  AG 
Sbjct: 1436 SAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGD 1495

Query: 140  PEGYEEEEEEE---EEEDEDEDEDEDEAGSELGEG-----EEEVGLSYLMKEEIQDEEDD 191
            PE   E +EE    E+  + + ++  E  +E  EG     E +      ++   Q+  + 
Sbjct: 1496 PEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQ 1555

Query: 192  DDYVEEGEEEEE 203
            DD  ++  E +E
Sbjct: 1556 DDTFQDCAETQE 1567



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 13/126 (10%)

Query: 110  EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL- 168
            +D+E  + EEED+E    +D + ++ +    E  E E+EE   E   E  +  E   +L 
Sbjct: 1406 DDHE--EEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLN 1463

Query: 169  ---GEGEEE------VGLSYLMKEEIQDEEDDDDYVEEGEEEEEE-EEGGLRGEKRKRDA 218
               G    E      V L+     E ++   D + V E +EE    E+   + +K  ++ 
Sbjct: 1464 VQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEV 1523

Query: 219  EDDGEE 224
            + + +E
Sbjct: 1524 DTEFKE 1529


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 25/139 (17%)

Query: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE-------------EEEEDE 155
           ++D+E    +EED    +EDDE  E+ E G   G  ++E+E             EEEE+E
Sbjct: 479 KDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEE 538

Query: 156 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE---------EEEEEE 206
           D++E+E+E   E  E   EVG + L  +  ++EE++++ +EE E          +  EE 
Sbjct: 539 DKEEEEEEEDEERREERAEVG-APLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEA 597

Query: 207 GGLRGEKRKRDAEDDGEEE 225
           GG   E  +   ED G ++
Sbjct: 598 GGASSE--EESGEDTGPQD 614



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 40/173 (23%), Positives = 74/173 (42%), Gaps = 52/173 (30%)

Query: 106 GFDQEDNEAPDSEEEDDED-----------------GDEDDEE--EEENEAGPPEGYEEE 146
           G D ED+E  + EEE++E+                 G E+DE+  +  +  GP   ++  
Sbjct: 184 GHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGH 243

Query: 147 EEEEEEEDEDEDEDED-------------------EAGSELGEGEEEVGLSYLMKEEIQD 187
           EE+++++D+D+D+D+D                   E   ++ +G      S+  +   +D
Sbjct: 244 EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED 303

Query: 188 EEDDDDYVEE-------GEEEEEEEEGGLRGE-------KRKRDAEDDGEEED 226
           + DDDD   E        ++  +EE   + GE        R +   D+ E+ED
Sbjct: 304 DNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDED 356



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 21/121 (17%)

Query: 105 DGFDQEDNE-----APDSEEEDDEDGDEDDEEEEEN------EAGPPEGYEEEEEEEEEE 153
           D  D+ED E     + + EEE++ED +E++EEE+E       E G P   +  EEEEEEE
Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEE 574

Query: 154 DEDEDEDEDE---AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLR 210
            E  +EDE       + L   EE  G S       ++E  +D   ++ +E    + G L 
Sbjct: 575 -EGLEEDEPRFTIIPNPLDRREEAGGAS------SEEESGEDTGPQDAQEYGNYQPGSLC 627

Query: 211 G 211
           G
Sbjct: 628 G 628



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 21/128 (16%)

Query: 117 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED-------------- 162
           S +++DED     E           G++ E++E EEE+E+E+E+E+              
Sbjct: 159 SHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRG 218

Query: 163 ---EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE 219
              E   ++ +G    G S+  +   +D++DDDD     ++++++++  +    +    +
Sbjct: 219 HGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDD----DDDDDDDDDVSIEYRHQAHRHQ 274

Query: 220 DDGEEEDD 227
             G EED+
Sbjct: 275 GHGIEEDE 282



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 28/148 (18%)

Query: 108 DQEDNEAPDSEE------------EDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDE 155
           D++++E   SE             + ++D  E++EEEEE E      Y  +         
Sbjct: 162 DEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGS 221

Query: 156 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDD-------------YVEEGEEEE 202
           +EDED  +     G      G      ++  D++DDDD             +   G EE+
Sbjct: 222 EEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEED 281

Query: 203 EEEEGGLR---GEKRKRDAEDDGEEEDD 227
           E+   G        R R  E+D  ++DD
Sbjct: 282 EDVSDGHHHRDPSHRHRSHEEDDNDDDD 309



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 42/175 (24%), Positives = 73/175 (41%), Gaps = 66/175 (37%)

Query: 118 EEEDDEDGDED--------------DEEEEENE----------AGPPEGYEEEEEEEEEE 153
           +EE+DED   +              DEEEEE E          +  P G++ +EE+ ++E
Sbjct: 350 DEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDE 409

Query: 154 DEDE----------DEDEDEAGSELGEG---------EEEVG------------------ 176
            + E           E+++E  +ELG           +EE G                  
Sbjct: 410 YKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHT 469

Query: 177 ----LSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKR-KRDAEDDGEEED 226
                S+L K++ ++E++ ++     EE++E  E G +G     RD ED+ +EE+
Sbjct: 470 VVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEE 524



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 41/139 (29%)

Query: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE-----------EEEEEDEDE 157
           +ED++  D +++DD+D D   E   +       G EE+E+                 E++
Sbjct: 244 EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED 303

Query: 158 DEDEDEAGSELG-----------------EGEEEVGLSYLMKEEIQDEEDDDD------- 193
           D D+D+  +E G                  GE    +     +  +DEE+D+D       
Sbjct: 304 DNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWH 363

Query: 194 ----YVEEG--EEEEEEEE 206
               +V  G  +EEEEEEE
Sbjct: 364 QGPQHVHHGLVDEEEEEEE 382



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 26/107 (24%)

Query: 115 PDSEEEDDEDGDEDDEEEE--ENEAGPPEGYEEEEEEEEEEDED-------------EDE 159
           P    +D + GDE    EE      G   G+     E+ E+  +             +DE
Sbjct: 104 PGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDE 163

Query: 160 DEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
           DEDE  S            ++++   +  + +DD   EGEE EEEEE
Sbjct: 164 DEDEVVSSEHH-------HHILRHGHRGHDGEDD---EGEE-EEEEE 199


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 44/140 (31%), Positives = 78/140 (55%), Gaps = 13/140 (9%)

Query: 96  ELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDE 155
           E ++  T   G  +E   A    EE+D+  DE+D+ EE+ EAG     +E+++E+ EED 
Sbjct: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-----KEDKDEKGEEDG 157

Query: 156 DEDEDEDEAGSELGE------GEEEVGLSYLMKEEIQDEEDDDDYVE--EGEEEEEEEEG 207
            ED++ +E G +  E      GE+  G     KE+ +DE++++D  E  +G+E E+ +E 
Sbjct: 158 KEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEK 217

Query: 208 GLRGEKRKRDAEDDGEEEDD 227
           G + E +    ++D +E +D
Sbjct: 218 GDKKEGKDVKVKEDEKERED 237



 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 25/150 (16%)

Query: 86  NLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEE 145
           N+ED  E             G  +E   A    EE+D+  DE+D+ EE+ EAG     +E
Sbjct: 104 NIEDATEK-----------GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-----KE 147

Query: 146 EEEEEEEEDEDEDEDEDEAGSELGE------GEEEVGLSYLMKEEIQDEEDDDDYVEEG- 198
           +++E+ EED  ED++ +E G +  E      GE+  G     KE+ +DE++++D  E G 
Sbjct: 148 DKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207

Query: 199 --EEEEEEEEGGLRGEKRKRDAEDDGEEED 226
             E E+ +E+G  +  K  +  ED+ E ED
Sbjct: 208 GKENEDGKEKGDKKEGKDVKVKEDEKERED 237



 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 49/143 (34%), Positives = 76/143 (53%), Gaps = 28/143 (19%)

Query: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED-------- 156
           D  DQ + +    +E+ DE G+ED +E++    G  +G + +E+E+ ++ ED        
Sbjct: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKN---GNEKGEDAKEKEDGKKGEDGKGNGEDG 189

Query: 157 ----EDEDEDEAGSELGEGEE-EVGLSYLMKEEIQDEEDDDDYVEEGEEEEE---EEEGG 208
               EDE E+E   E G+G+E E G     KE+   +E  D  V+E E+E E   E+EGG
Sbjct: 190 KEKGEDEKEEEDRKETGDGKENEDG-----KEKGDKKEGKDVKVKEDEKEREDGKEDEGG 244

Query: 209 LRGE--KRKRD--AEDDGEEEDD 227
              E  K K D   E++G+EED+
Sbjct: 245 NEEEAGKEKEDLKEEEEGKEEDE 267



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 23/145 (15%)

Query: 88  EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 147
           EDY E+      +IT     ++E  E    +EE+ ED  E   E++E  A      + EE
Sbjct: 74  EDYNENAKNGEAKITEAPASEKEIVEV---KEENIEDATEKGGEKKEAVAAE---VKNEE 127

Query: 148 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 207
           E+++E++ED++E++ EAG E  + + E           +D ++D +  E+GE+ +E+E+G
Sbjct: 128 EDQKEDEEDQNEEKGEAGKEDKDEKGE-----------EDGKEDKNGNEKGEDAKEKEDG 176

Query: 208 GL------RGEKRKRDAEDDGEEED 226
                    GE  K   ED+ EEED
Sbjct: 177 KKGEDGKGNGEDGKEKGEDEKEEED 201



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 36/109 (33%), Positives = 65/109 (59%), Gaps = 13/109 (11%)

Query: 105 DGFDQEDNEA--PDSEEEDDEDGDEDDEEE----EENEAGPPEGYEEEEEE---EEEEDE 155
           DG   ED +    D +E+ +++ +E+D +E    +ENE G  +G ++E ++   +E+E E
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE 234

Query: 156 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 204
            ED  EDE G+E   G+E+  L    KEE + +E+D+   ++G++EE +
Sbjct: 235 REDGKEDEGGNEEEAGKEKEDL----KEEEEGKEEDEIKEDDGKKEEPQ 279



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 36/114 (31%), Positives = 65/114 (57%), Gaps = 15/114 (13%)

Query: 105 DGFDQEDNEAPDSEEEDDEDGDE--DDEEEEENEAGPPEGYEEEEEEEEEEDED------ 156
           D  ++ED +  +  + + EDG E  +DE+EEE+     +G E E+ +E+ + ++      
Sbjct: 169 DAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKV 228

Query: 157 -EDEDEDEAGSE-LGEGEEEVGLSYLMKEEIQDEED--DDDYVEEGEEEEEEEE 206
            EDE E E G E  G  EEE G     KE++++EE+  ++D ++E + ++EE +
Sbjct: 229 KEDEKEREDGKEDEGGNEEEAGKE---KEDLKEEEEGKEEDEIKEDDGKKEEPQ 279



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 4/103 (3%)

Query: 129 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE 188
           +E+  EN         E    E+E  E ++E+ ++A  + GE +E V      +EE Q E
Sbjct: 73  EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132

Query: 189 EDDDDYVEEGE--EEEEEEEGGLRGEKRKRDAE--DDGEEEDD 227
           +++D   E+GE  +E+++E+G   G++ K   E  +D +E++D
Sbjct: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 12/109 (11%)

Query: 117 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVG 176
           +E + +   +ED  E  +N           E+E  E  E+  ED  E G     GE++  
Sbjct: 64  AETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG-----GEKKEA 118

Query: 177 LSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 225
           ++  +K E +D+++D       EE++ EE+G    E +    E+DG+E+
Sbjct: 119 VAAEVKNEEEDQKED-------EEDQNEEKGEAGKEDKDEKGEEDGKED 160



 Score = 36.2 bits (82), Expect = 0.024
 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)

Query: 118 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEE-EEEEEDEDEDEDEDEAGS 166
           +E++ EDG ED+   EE      E  +EEEE +EE+E +++D  ++E  S
Sbjct: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/144 (27%), Positives = 82/144 (56%), Gaps = 5/144 (3%)

Query: 67   RKQNLKNLKSLDLFNCEITNLED---YRESIFELLQQITYLDGFDQEDNEAPDSEEE-DD 122
            RK+  +  K  + F+ ++  +E    + E +  LL ++   +    E+ E  + EEE ++
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259

Query: 123  EDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMK 182
            E+  E++EE +E E G  +  E+EEEE++++ +++ ++E +   E+ E +EE+ +S    
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI-MSEEET 2318

Query: 183  EEIQDEEDDDDYVEEGEEEEEEEE 206
            E + DEE++++     EE + E+E
Sbjct: 2319 ESLSDEEEEEESCSLEEEVDREKE 2342



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 8/137 (5%)

Query: 91   RESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEE 150
            +E     + ++   + F +E     D  E+ +    E++EE EE E    E  EEE  EE
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEE----EREEEEVREE 2265

Query: 151  EEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLR 210
            EEE ++E+E E E   E  E E++       KEE+Q++E   +  EE EE   EEE    
Sbjct: 2266 EEERKEEEEGE-EKQVEKEEEEKKKKKKEKKKEEVQEKE---EVFEEKEEIMSEEETESL 2321

Query: 211  GEKRKRDAEDDGEEEDD 227
             ++ + +     EEE D
Sbjct: 2322 SDEEEEEESCSLEEEVD 2338



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 37/142 (26%), Positives = 75/142 (52%), Gaps = 14/142 (9%)

Query: 87   LEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDE-EEEENEAGPPEGYEE 145
            L+D  E   E  + I +L    ++  EA   ++  ++   + DE E EE+ +   E   +
Sbjct: 2176 LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLD 2235

Query: 146  EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 205
            E E++E    +E+E+ +E      E E E       +EE+++EE++    EEGEE++ E+
Sbjct: 2236 ELEKQESLSSEEEEEREE------EEERE-------EEEVREEEEERKEEEEGEEKQVEK 2282

Query: 206  EGGLRGEKRKRDAEDDGEEEDD 227
            E   + +K+K   +++ +E+++
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEE 2304



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 29/128 (22%)

Query: 117  SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE-------------DEDE 163
            S+E+  +D +E   EEE +     EG E+E++  EE+   ++E             ++  
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSR----EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588

Query: 164  AGSELGEGEEEVGLSYLMKEEIQDE-----------EDDDDYVE-EGEEEEEEEEGGLRG 211
            A  E    +EE  L+   ++  Q+E           +DD +  + EG+  ++EE    RG
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648

Query: 212  EKRKRDAE 219
            EK  ++AE
Sbjct: 1649 EKLSQEAE 1656



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 7/102 (6%)

Query: 109  QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-GYEEEEEEEEE----EDEDEDEDEDE 163
            Q+  E P  E+  D    E  +E EE E    E  ++EEE  +EE    E++ +  +E+E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754

Query: 164  AGSELGE--GEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 203
            A +   E   EEE  L+   +  IQ++E    + E+  EEEE
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796



 Score = 29.3 bits (64), Expect = 2.9
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 4/101 (3%)

Query: 130  EEEEENEAGPPEGYEEEEEEEEEE---DEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQ 186
            EEE+ ++AG     EEE  +E+++   +E +   E+   S+  E + +      ++EE+ 
Sbjct: 1492 EEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVS 1551

Query: 187  DE-EDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226
             E E+ +  V E +   +EE    R  +++  AE    +E+
Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592



 Score = 27.7 bits (60), Expect = 8.4
 Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 23/129 (17%)

Query: 116  DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEE--------EEDEDEDEDEDEAGSE 167
            D  E    +G    +EE   + G     E E+  ++        E+   E+E   + G +
Sbjct: 1626 DDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGK 1685

Query: 168  LGE------------GEEEVGLSYLMKE---EIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
            L E             + E  L +  KE   E+++ E D + +   EEE  +EEG L  E
Sbjct: 1686 LAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEE 1745

Query: 213  KRKRDAEDD 221
            K+K   E++
Sbjct: 1746 KKKLAEEEE 1754


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 90  YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 149
           Y+E I    + +T L G + + +      + + E+ DE+DE++E+          E+EEE
Sbjct: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 657

Query: 150 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 209
           E++E+ D  ED  ++     E E E G      E  +D+ED+DD  ++ E+E+ E EG  
Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 712

Query: 210 RGEKRKRDAED 220
                  D+ D
Sbjct: 713 SSSSSSGDSSD 723



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 141 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 199
           E  E++EE+E++EDEDE+E++DE G    +G +    S   + E  DE E+DD+  ++ E
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 200 EEEEEEEGGLRGEKRKRDAEDDGEEED 226
           +++E+E+    G      +  D  + D
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 147 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 200
           + + E E++DE+      EDE+E   E G+  E+ G S         E   +D  E+G+E
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 686

Query: 201 EEEEEEGGLRGEKRKRDAEDDGEEEDD 227
            EE++E        + D EDD E+ED+
Sbjct: 687 NEEDDED-------EDDDEDDDEDEDN 706



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 156
           D+ ++   + E+++DED DEDD+E+E+NE+           +  + D +
Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 35.0 bits (79), Expect = 0.053
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 111 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
           ++E+ D +E +++D DEDD+E+++         E+E+ E E          D + S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 725


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 90  YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 149
           Y+E I    + +T L G + + +      + + E+ DE+DE++E+          E+EEE
Sbjct: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 657

Query: 150 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 209
           E++E+ D  ED  ++     E E E G      E  +D+ED+DD  ++ E+E+ E EG  
Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 712

Query: 210 RGEKRKRDAED 220
                  D+ D
Sbjct: 713 SSSSSSGDSSD 723



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 141 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 199
           E  E++EE+E++EDEDE+E++DE G    +G +    S   + E  DE E+DD+  ++ E
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 200 EEEEEEEGGLRGEKRKRDAEDDGEEED 226
           +++E+E+    G      +  D  + D
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 147 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 200
           + + E E++DE+      EDE+E   E G+  E+ G S         E   +D  E+G+E
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 686

Query: 201 EEEEEEGGLRGEKRKRDAEDDGEEEDD 227
            EE++E        + D EDD E+ED+
Sbjct: 687 NEEDDED-------EDDDEDDDEDEDN 706



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 156
           D+ ++   + E+++DED DEDD+E+E+NE+           +  + D +
Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 35.0 bits (79), Expect = 0.053
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 111 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
           ++E+ D +E +++D DEDD+E+++         E+E+ E E          D + S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 725


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 90  YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 149
           Y+E I    + +T L G + + +      + + E+ DE+DE++E+          E+EEE
Sbjct: 645 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 694

Query: 150 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 209
           E++E+ D  ED  ++     E E E G      E  +D+ED+DD  ++ E+E+ E EG  
Sbjct: 695 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 749

Query: 210 RGEKRKRDAED 220
                  D+ D
Sbjct: 750 SSSSSSGDSSD 760



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 141 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 199
           E  E++EE+E++EDEDE+E++DE G    +G +    S   + E  DE E+DD+  ++ E
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735

Query: 200 EEEEEEEGGLRGEKRKRDAEDDGEEED 226
           +++E+E+    G      +  D  + D
Sbjct: 736 DDDEDEDNESEGSSSSSSSSGDSSDSD 762



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)

Query: 147 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 200
           + + E E++DE+      EDE+E   E G+  E+ G S         E   +D  E+G+E
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 723

Query: 201 EEEEEEGGLRGEKRKRDAEDDGEEEDD 227
            EE++E        + D EDD E+ED+
Sbjct: 724 NEEDDED-------EDDDEDDDEDEDN 743



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 156
           D+ ++   + E+++DED DEDD+E+E+NE+           +  + D +
Sbjct: 716 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 35.0 bits (79), Expect = 0.053
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 111 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
           ++E+ D +E +++D DEDD+E+++         E+E+ E E          D + S+
Sbjct: 715 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 762


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 48/147 (32%), Positives = 69/147 (46%), Gaps = 19/147 (12%)

Query: 88   EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 147
            ED +ES+ E  +        ++E+    + EEEDD+D D DD +E EN+       E  E
Sbjct: 1035 EDEKESLSEEQEST------EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088

Query: 148  EEEEEEDEDE------DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 201
            ++E + DE+E       + E  + SE  E  E    S   +      ED+++ V   EEE
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSS---ESSPSSSEDEEEVVAREEEE 1145

Query: 202  EEEEEGGLRGEKR----KRDAEDDGEE 224
            EEEEE  +  E        D E DGEE
Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEE 1172



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 5/115 (4%)

Query: 111  DNEAPDSEEEDDED-GDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 169
            D E  +SE E D D  D   E  + +  G   G         E D   +EDE E+ SE  
Sbjct: 988  DEEDEESERERDRDMADTPCELAKRDPKGV--GVRRRPARPLELDSGGEEDEKESLSEEQ 1045

Query: 170  EGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 224
            E  EE       +EE ++++DDDD  +  E E ++E+  L     K + + D EE
Sbjct: 1046 ESTEEE--EEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 36/119 (30%)

Query: 140  PEGYEEEEEEEEEEDEDED---------------------------------EDEDEAGS 166
            P    +EE+EE E + D D                                 EDE E+ S
Sbjct: 983  PSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLS 1042

Query: 167  ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 225
            E  E  EE       +EE ++E+DDDD  ++ +E E ++E     E  ++D  D  EEE
Sbjct: 1043 EEQESTEE---EEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 6/87 (6%)

Query: 146  EEEEEEEEDEDEDEDEDEAGSELGEGEEE-VGLSYLMKEEIQ----DEEDDDDYVEEGEE 200
            +EE+EE E E  D D  +   EL + + + VG+       ++     EED+ + + E +E
Sbjct: 988  DEEDEESERE-RDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQE 1046

Query: 201  EEEEEEGGLRGEKRKRDAEDDGEEEDD 227
              EEEE     E+ + D +DD ++ D+
Sbjct: 1047 STEEEEEAEEEEEEEDDDDDDSDDRDE 1073



 Score = 34.7 bits (78), Expect = 0.069
 Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 72/174 (41%)

Query: 108  DQEDNEAPDSEEEDDED-----------GDEDDEE-----------------------EE 133
            D +D++  D  E DDED           GD D+EE                       E 
Sbjct: 1064 DDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFES 1123

Query: 134  ENEAGPPEGY--------EEEEEEEEEE-----------DEDEDEDEDEAGSELGEGEEE 174
             +E+ P            EEEEEEEEEE            ED ++D +EA   L  G   
Sbjct: 1124 SSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAA--LAPGAPA 1181

Query: 175  VGLSYLMKEEIQDEED-----------DDDYVEEGEEE-----EEEEEGGLRGE 212
            V  S  M+EE+  E +           D+  +  G EE     E  EE GL  E
Sbjct: 1182 VD-SLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQE 1234


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 60/245 (24%), Positives = 109/245 (44%), Gaps = 42/245 (17%)

Query: 4   KKKINLELRNRSPEEVTE----LVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLAR 59
           ++++  E R R  ++  E    L  +  L    + E        L+ L    VE+ S   
Sbjct: 379 EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDS 438

Query: 60  LPSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEE 119
           LP    + +   +      L + E++   +   ++ E+++Q     G  +++   P  E 
Sbjct: 439 LPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAV-EVMEQ-----GVPEKEETPPPVEP 492

Query: 120 EDDEDGDE----------DDEEEEENEAGP--------PEGYEEEEEEEEEEDEDEDEDE 161
           E++ED ++           DEE E+ E           PE  EEEEEEEEE++E E+E+E
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE 552

Query: 162 DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 221
           +E  SE  EG+EE        E++ DE+D    +++   +E   +        + D++DD
Sbjct: 553 EEGESEGSEGDEE-------DEKVSDEKDSGKTLDKKPSKEMSSDS-------EYDSDDD 598

Query: 222 GEEED 226
             +E+
Sbjct: 599 RTKEE 603



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 7/106 (6%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 169
           E N+     +E+ E+ +E++EEEEE+E       EEEEEEE E +  E ++EDE  S+  
Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEES-----EEEEEEEGESEGSEGDEEDEKVSD-- 571

Query: 170 EGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 215
           E +    L     +E+  + + D   +  +EE   ++   R EKR+
Sbjct: 572 EKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRR 617



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 28/130 (21%), Positives = 59/130 (45%), Gaps = 12/130 (9%)

Query: 106 GFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG 165
           G  Q+ N+  D  EED+++  +  E    N +G  E  +E +E  +     +   +++ G
Sbjct: 152 GKAQKSNKKWDGSEEDEDNSKKIKERSRINSSG--ESGDESDEFLQSRKGQKKNQKNKPG 209

Query: 166 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE----------EEEEGGLRGEKRK 215
             +  G E+   S+ +K   Q + +  +   +  +EE          EE E G + + ++
Sbjct: 210 PNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQ 269

Query: 216 RDAEDDGEEE 225
           ++++   EEE
Sbjct: 270 KESQRKFEEE 279



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/119 (23%), Positives = 58/119 (48%), Gaps = 8/119 (6%)

Query: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEE----EEEDEDEDEDEDEA 164
           ++DNE    +++  +   E +E+E+E + GP +   +  +E     +EE+E +  +E+E 
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGE 223
              L    EE+      +E ++ E+ +    +E E +E  ++ G    K +R+A    E
Sbjct: 366 IKRL----EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE 420



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 30/120 (25%), Positives = 64/120 (53%), Gaps = 18/120 (15%)

Query: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 168
           +E  E P + E+D+E GD+  +++++ +        E+EE+E+E+ +   +   +A  E 
Sbjct: 296 EEKAETPTAAEDDNE-GDKKKKDKKKKKG-------EKEEKEKEKKKGPSKATVKAMQE- 346

Query: 169 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE--EEEEGGLRGEKRKRDAEDDGEEED 226
                   L+ L +EE + + ++++ ++  EE E   +EE  L  EKR+R  + + E ++
Sbjct: 347 -------ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE 399



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 23/117 (19%), Positives = 52/117 (44%), Gaps = 25/117 (21%)

Query: 127 EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQ 186
           E++EEE  ++    +G + +++  ++ D +E ED+D    +  + + E+           
Sbjct: 85  ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEM---------YS 135

Query: 187 DEEDDDDYVE----------------EGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
             +DDDD+ +                +G EE+E+    ++   R   + + G+E D+
Sbjct: 136 GSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDE 192



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 13/116 (11%)

Query: 123 EDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED-------EDEDEDEAGSELGEGEEEV 175
           E G+EDD+   + +    +  E++E E ++ DE+       ++++E E G +  + +++ 
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK-DQSKQKE 271

Query: 176 GLSYLMKEEIQDEEDDDDYVEEGEEEEEE----EEGGLRGEKRKRD-AEDDGEEED 226
                 +E ++ +   D  V    EE+ E     E    G+K+K+D  +  GE+E+
Sbjct: 272 SQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEE 327



 Score = 31.6 bits (70), Expect = 0.58
 Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 16/123 (13%)

Query: 109 QEDNEAPDSEEED-DEDGDEDDEE----EEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
           ++ N++ DS ++D D D    + E     +E E    +G +++E+++++ DED+   E E
Sbjct: 4   KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63

Query: 164 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGE 223
             S   +G +    +  +K             E  EEE   ++   +G+K K+ + DD +
Sbjct: 64  ELSLEAQGIKADRETVAVKP-----------TENNEEEFTSKDKKKKGQKGKKQSFDDND 112

Query: 224 EED 226
            E+
Sbjct: 113 SEE 115



 Score = 29.3 bits (64), Expect = 2.9
 Identities = 31/164 (18%), Positives = 68/164 (41%), Gaps = 12/164 (7%)

Query: 74  LKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEE 133
           LK L+  + E   ++  RE++  +       + F  +D +    + +     D D EE E
Sbjct: 59  LKELEELSLEAQGIKADRETV-AVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE 117

Query: 134 ENEAGPPEGYEEEEEEEEEEDEDEDEDE---------DEAGSELGEGEEEVGLSYLMKEE 184
           + ++   +  + + E     D+D+D ++          ++  +    EE+   S  +KE 
Sbjct: 118 DKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKER 177

Query: 185 IQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE-DDGEEEDD 227
            +     +   +E +E  +  +G  + +K K     + G E+DD
Sbjct: 178 SRINSSGES-GDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDD 220



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 142 GYEEEEEEEEEEDEDEDED----EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEE 197
           G +++ + E+   +D D D    E E      E E +       KE+ + + D+DD ++E
Sbjct: 2   GKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61

Query: 198 GEEEEEEEEG 207
            EE   E +G
Sbjct: 62  LEELSLEAQG 71


>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
          Length = 406

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 12/118 (10%)

Query: 91  RESIFELLQQITYLDGFDQEDNE--APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 148
           +E+++  +Q  +     + E+N+  AP   EE++E  ++D+EE ++      E  EEEEE
Sbjct: 247 QETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE 306

Query: 149 --EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 204
             +EEEE EDE+E+E E    + EGEEE     L +EE+++EE   + +EE E+  EE
Sbjct: 307 VEDEEEEVEDEEEEEVEEAEYVEEGEEE-----LEEEELEEEE---EVLEENEQRGEE 356



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)

Query: 107 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDEDEAG 165
           +DQE  +A ++ EE++E  DE++E E+E E    E  Y EE EEE EE+E E+E+E    
Sbjct: 290 YDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349

Query: 166 SELGEGEEEVGLSYLMKEEIQDEEDDDDYV 195
           +E    E  + L   +   ++ EE  ++++
Sbjct: 350 NEQRGEEFHLPLEMPLSIFVEAEEKRENFI 379



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)

Query: 88  EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 147
           E+Y + + +  +     +  + E+ E  D EEE+ E+ +  +E EEE         EEEE
Sbjct: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE--------LEEEE 339

Query: 148 EEEEEEDEDEDEDEDE 163
            EEEEE  +E+E   E
Sbjct: 340 LEEEEEVLEENEQRGE 355


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)

Query: 108 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 163
           D ED+    SEEED E   DG+E + +EE   A   E  EE E+EEEEEE+E+ DE+E+E
Sbjct: 3   DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 164 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
              +    +   G   L + ++ DE +D+D  E+G E+  E+E
Sbjct: 61  EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 164
           E  E P+ EEE++E+ + D+EEEEE++  PP+     G+  +E + ++E EDED+ ED  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 221
                 G E++    L KEEI+    D+  +      +E+  G  R +   RD  ++
Sbjct: 95  ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)

Query: 143 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 202
           + EEE+ E   D +E E ++E  S  G  +E         EE +DEE++++  EE  +EE
Sbjct: 9   FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57

Query: 203 EEEEGGLRGEKRKR---------DAEDDGEEED 226
           EEEE   R  K+ R         D +D+ E+ED
Sbjct: 58  EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 188 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 227
           EE+D +   +GEE E +EE     G +++ + ED+ EEE++
Sbjct: 11  EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 153 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
           + ED +  E+E      +GEE              E D++     G E+EEE E     E
Sbjct: 3   DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49

Query: 213 KRKRDAEDDGEEEDD 227
           + +   E++ EE+DD
Sbjct: 50  EEEEYDEEEEEEDDD 64


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)

Query: 108 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 163
           D ED+    SEEED E   DG+E + +EE   A   E  EE E+EEEEEE+E+ DE+E+E
Sbjct: 3   DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 164 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
              +    +   G   L + ++ DE +D+D  E+G E+  E+E
Sbjct: 61  EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 164
           E  E P+ EEE++E+ + D+EEEEE++  PP+     G+  +E + ++E EDED+ ED  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 221
                 G E++    L KEEI+    D+  +      +E+  G  R +   RD  ++
Sbjct: 95  ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)

Query: 143 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 202
           + EEE+ E   D +E E ++E  S  G  +E         EE +DEE++++  EE  +EE
Sbjct: 9   FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57

Query: 203 EEEEGGLRGEKRKR---------DAEDDGEEED 226
           EEEE   R  K+ R         D +D+ E+ED
Sbjct: 58  EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 188 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 227
           EE+D +   +GEE E +EE     G +++ + ED+ EEE++
Sbjct: 11  EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 153 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
           + ED +  E+E      +GEE              E D++     G E+EEE E     E
Sbjct: 3   DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49

Query: 213 KRKRDAEDDGEEEDD 227
           + +   E++ EE+DD
Sbjct: 50  EEEEYDEEEEEEDDD 64


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)

Query: 108 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 163
           D ED+    SEEED E   DG+E + +EE   A   E  EE E+EEEEEE+E+ DE+E+E
Sbjct: 3   DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 164 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
              +    +   G   L + ++ DE +D+D  E+G E+  E+E
Sbjct: 61  EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)

Query: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 164
           E  E P+ EEE++E+ + D+EEEEE++  PP+     G+  +E + ++E EDED+ ED  
Sbjct: 37  EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94

Query: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 221
                 G E++    L KEEI+    D+  +      +E+  G  R +   RD  ++
Sbjct: 95  ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)

Query: 143 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 202
           + EEE+ E   D +E E ++E  S  G  +E         EE +DEE++++  EE  +EE
Sbjct: 9   FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57

Query: 203 EEEEGGLRGEKRKR---------DAEDDGEEED 226
           EEEE   R  K+ R         D +D+ E+ED
Sbjct: 58  EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 188 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 227
           EE+D +   +GEE E +EE     G +++ + ED+ EEE++
Sbjct: 11  EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)

Query: 153 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
           + ED +  E+E      +GEE              E D++     G E+EEE E     E
Sbjct: 3   DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49

Query: 213 KRKRDAEDDGEEEDD 227
           + +   E++ EE+DD
Sbjct: 50  EEEEYDEEEEEEDDD 64


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.299    0.129    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,211,833
Number of Sequences: 37866
Number of extensions: 784548
Number of successful extensions: 62589
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1487
Number of HSP's successfully gapped in prelim test: 569
Number of HSP's that attempted gapping in prelim test: 6716
Number of HSP's gapped (non-prelim): 19519
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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