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Search of human proteins with 209969682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209969682 coiled-coil domain-containing-like [Homo sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209969682 coiled-coil domain-containing-like [Homo sapiens] 599 e-172
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 50 2e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 50 2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 7e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 3e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 46 5e-05
gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens] 46 5e-05
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 46 5e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 6e-05
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 45 6e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 8e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 8e-05
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 45 8e-05
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 45 1e-04
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 45 1e-04
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 44 2e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 43 3e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 43 3e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 43 3e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 43 3e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 43 3e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 43 4e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 43 4e-04
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 42 8e-04
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 42 8e-04
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 41 0.001
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 41 0.001
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 41 0.001
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 41 0.001
>gi|209969682 coiled-coil domain-containing-like [Homo sapiens]
Length = 297
Score = 599 bits (1545), Expect = e-172
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MGEHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTML 60
MGEHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTML
Sbjct: 1 MGEHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTML 60
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE
Sbjct: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM 180
EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM
Sbjct: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM 180
Query: 181 QKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKELSDIWSAVHVLQNSI 240
QKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKELSDIWSAVHVLQNSI
Sbjct: 181 QKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKELSDIWSAVHVLQNSI 240
Query: 241 DSLTLCSGACPKASSLRGHKGHQCLSPPLPSWDSDSDCDQDLSQPPFSKSGRSFPPA 297
DSLTLCSGACPKASSLRGHKGHQCLSPPLPSWDSDSDCDQDLSQPPFSKSGRSFPPA
Sbjct: 241 DSLTLCSGACPKASSLRGHKGHQCLSPPLPSWDSDSDCDQDLSQPPFSKSGRSFPPA 297
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 50.4 bits (119), Expect = 2e-06
Identities = 54/230 (23%), Positives = 100/230 (43%), Gaps = 34/230 (14%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTG-RQGEKEEHKWG 93
EL+S+ ++LQAQ + E N E++ Q+ KIQ+ EE + + E+EE W
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR 329
Query: 94 MEQGRQELYGALTQGLQGL---EKTLRDSEEMQRA------RTTRCLQLLAQEIRDSKKF 144
E+ E + + + E+ +R+ EE R R ++ ++I++ ++
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEE 389
Query: 145 LWEELELVREEVTFIYQKLQAQEDEISENLVNIQK------------------MQKTQVK 186
+W + E +RE+ +K+ QE ++ E I++ MQ + K
Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Query: 187 CRKILTKM-----KQQGHETAACPETEEIPQGASGCWKDD-LQKELSDIW 230
R++ KM K Q E + E+I + W+ + L K+ IW
Sbjct: 450 LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Score = 45.8 bits (107), Expect = 5e-05
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 17/204 (8%)
Query: 6 QVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESC 65
Q + + K++ + M +K+ E E + ++ Q K + + E+E
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDEKIREQEEEMW 430
Query: 66 LQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRA 125
Q+ KI++LEE++ + + E K Q +E + +Q E+ +++ EE
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKM---QEEEEKMQEQEEKIQRQEEKIQEQEE---- 483
Query: 126 RTTRCLQLLAQE--IRDSKKFLWEELELV---REEVTFIYQKLQAQEDEISENLVNI--- 177
+T R +LL QE I + ++ +W + E + E++ +K+Q QE+++ E V +
Sbjct: 484 KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543
Query: 178 -QKMQKTQVKCRKILTKMKQQGHE 200
+KMQ+ +V+ +++ ++ + G +
Sbjct: 544 EEKMQEQEVRLQELEERLGKLGQK 567
Score = 43.9 bits (102), Expect = 2e-04
Identities = 40/198 (20%), Positives = 96/198 (48%), Gaps = 9/198 (4%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
EQ + K++ + + +K+ R E + + + Q + E + E+E
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGAL---TQGLQGLEKTLRDSEE 121
Q+ +Q +++ + E+EE W E+ +EL + + L+ +E+ +++ EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 122 MQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQ--KLQAQEDEISENLVNIQK 179
+ + + +Q ++I++ ++ W + +L+++E Q K+ QE+++ E +K
Sbjct: 463 KMQEQEEK-IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE---QEEK 518
Query: 180 MQKTQVKCRKILTKMKQQ 197
MQ+ + K ++ KM++Q
Sbjct: 519 MQEQEEKMQRQEEKMREQ 536
Score = 35.0 bits (79), Expect = 0.079
Identities = 36/158 (22%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
E++ Q+ KI++ +E + E+EE W E+ +E + + EK +R+ +
Sbjct: 366 EEKMWRQEEKIREQDEKIQ------EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 121 EMQRA------RTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQ---KLQAQEDEIS 171
E R R ++ L + ++D ++ L E E ++EE + + K+Q QE++I
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 172 ENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEE 209
E + +K + KI + ++ + E EE
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 50.4 bits (119), Expect = 2e-06
Identities = 54/230 (23%), Positives = 100/230 (43%), Gaps = 34/230 (14%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTG-RQGEKEEHKWG 93
EL+S+ ++LQAQ + E N E++ Q+ KIQ+ EE + + E+EE W
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR 329
Query: 94 MEQGRQELYGALTQGLQGL---EKTLRDSEEMQRA------RTTRCLQLLAQEIRDSKKF 144
E+ E + + + E+ +R+ EE R R ++ ++I++ ++
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEE 389
Query: 145 LWEELELVREEVTFIYQKLQAQEDEISENLVNIQK------------------MQKTQVK 186
+W + E +RE+ +K+ QE ++ E I++ MQ + K
Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Query: 187 CRKILTKM-----KQQGHETAACPETEEIPQGASGCWKDD-LQKELSDIW 230
R++ KM K Q E + E+I + W+ + L K+ IW
Sbjct: 450 LREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Score = 45.8 bits (107), Expect = 5e-05
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 17/204 (8%)
Query: 6 QVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESC 65
Q + + K++ + M +K+ E E + ++ Q K + + E+E
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQE-EKRQEKMWRQEKKMREQDEKIREQEEEMW 430
Query: 66 LQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRA 125
Q+ KI++LEE++ + + E K Q +E + +Q E+ +++ EE
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKM---QEEEEKMQEQEEKIQRQEEKIQEQEE---- 483
Query: 126 RTTRCLQLLAQE--IRDSKKFLWEELELV---REEVTFIYQKLQAQEDEISENLVNI--- 177
+T R +LL QE I + ++ +W + E + E++ +K+Q QE+++ E V +
Sbjct: 484 KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543
Query: 178 -QKMQKTQVKCRKILTKMKQQGHE 200
+KMQ+ +V+ +++ ++ + G +
Sbjct: 544 EEKMQEQEVRLQELEERLGKLGQK 567
Score = 43.9 bits (102), Expect = 2e-04
Identities = 40/198 (20%), Positives = 96/198 (48%), Gaps = 9/198 (4%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
EQ + K++ + + +K+ R E + + + Q + E + E+E
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGAL---TQGLQGLEKTLRDSEE 121
Q+ +Q +++ + E+EE W E+ +EL + + L+ +E+ +++ EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 122 MQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQ--KLQAQEDEISENLVNIQK 179
+ + + +Q ++I++ ++ W + +L+++E Q K+ QE+++ E +K
Sbjct: 463 KMQEQEEK-IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE---QEEK 518
Query: 180 MQKTQVKCRKILTKMKQQ 197
MQ+ + K ++ KM++Q
Sbjct: 519 MQEQEEKMQRQEEKMREQ 536
Score = 35.0 bits (79), Expect = 0.079
Identities = 36/158 (22%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
E++ Q+ KI++ +E + E+EE W E+ +E + + EK +R+ +
Sbjct: 366 EEKMWRQEEKIREQDEKIQ------EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 121 EMQRA------RTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQ---KLQAQEDEIS 171
E R R ++ L + ++D ++ L E E ++EE + + K+Q QE++I
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 172 ENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEE 209
E + +K + KI + ++ + E EE
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.5 bits (114), Expect = 7e-06
Identities = 40/171 (23%), Positives = 86/171 (50%), Gaps = 9/171 (5%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGM 94
EL+S+ ++LQAQ + E N E++ Q+ KIQ+ EE + + ++E K
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 95 EQGR----QELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELE 150
++ + +E+ + ++ E+ + + EE R R + +++R ++ +WE+ E
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 151 LVR--EEVTFIYQKLQAQED--EISENLVNIQKMQKTQVKCRKILTKMKQQ 197
+R EE +K++ QE+ + E + +K Q+ + K + K+++Q
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/224 (22%), Positives = 93/224 (41%), Gaps = 38/224 (16%)
Query: 27 DSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLE-EVLSPTGRQG 85
D QK E+L+ +L+AQ L T L+ Q ++QLE E R
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 168
Query: 86 EKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLA-----QEIRD 140
+ + +EQ AL+ +K R EE+ + R L+L +E+++
Sbjct: 169 DSWKFAGELEQ-------ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
Query: 141 SKKFLWEELELVREEVTFI-------------------YQKLQAQEDEISENLVNIQKMQ 181
L E+L+LV E + I Q+LQA+ D + + L ++
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 182 KTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKE 225
+ QV+ ++ ++ QQ E + E+I + W++ +Q++
Sbjct: 282 QAQVEENELWNRLNQQ-QEEKMWRQEEKIQE-----WEEKIQEQ 319
Score = 40.4 bits (93), Expect = 0.002
Identities = 39/134 (29%), Positives = 66/134 (49%), Gaps = 17/134 (12%)
Query: 67 QQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRAR 126
Q+ KIQ+ EE + Q EK + M Q ++E G + EK E+MQ
Sbjct: 617 QEEKIQEQEEKIR---EQEEKIREQEEMTQEQEEKMG------EQEEKMCEQEEKMQEQE 667
Query: 127 TTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQ---KLQAQEDEISENLVNIQKMQKT 183
T Q ++IR+ +K + E+ E +RE+ + + K+ QE+++ E +KMQ+
Sbjct: 668 ETMWRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE---EKMQEQ 722
Query: 184 QVKCRKILTKMKQQ 197
+ K R+ KM +Q
Sbjct: 723 EEKMRRQEEKMWEQ 736
Score = 38.5 bits (88), Expect = 0.007
Identities = 50/244 (20%), Positives = 106/244 (43%), Gaps = 39/244 (15%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCEL------ESLKSQLQAQTKAFEFLNHSVT 58
EQ + + K++ + +M +K+ R E E ++ Q + + E +
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 59 ML-EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLR 117
M+ EKE KI++LEE + + E+EE + E+ R++ EK R
Sbjct: 385 MMWEKEE-----KIRELEEKMHEQEKIREQEEKRQEEEKIREQ------------EK--R 425
Query: 118 DSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNI 177
+E + R ++ ++IR+ +K +W + E + E+ ++ + +++E+ I
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 178 ----------QKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQ-KEL 226
+KM + + K RK K+ +Q E + E+I + W+ + + +E
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ--EEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 227 SDIW 230
++W
Sbjct: 544 EEMW 547
Score = 33.5 bits (75), Expect = 0.23
Identities = 36/153 (23%), Positives = 73/153 (47%), Gaps = 19/153 (12%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEH-------KWGMEQGRQELYGALTQGLQGL- 112
++E Q+ KI + EE+ + E+EE W E+ +E + + + +
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 113 --EKTLRDSEEMQRARTTRCLQ--LLAQEIRDSKKF-LWEELELVREEVTFIY---QKLQ 164
E+ +R+ EEM R Q + +E R ++ +W + E +RE+ ++ +K++
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 165 AQEDEISENLVNIQKMQKTQVKCRKILTKMKQQ 197
QE++ E +KM K + K R+ K+++Q
Sbjct: 595 EQEEKRQE---QEEKMWKQEEKIREQEEKIQEQ 624
Score = 32.3 bits (72), Expect = 0.52
Identities = 37/195 (18%), Positives = 89/195 (45%), Gaps = 29/195 (14%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCE--LESLKSQLQAQTKAFEFLNHSVTMLEK 62
EQ + + K++ + +K+ + E + + ++Q Q + + E+
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 63 ESCLQQIKI-QQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEE 121
+ Q+ K+ +Q E++ + E+EE W E+ +E + ++ E+ +R+ EE
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ----EKKIREQEEKIREQEE 696
Query: 122 MQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQ 181
M +++ ++ +WE+ E + E+ +K+Q QE+++ +KM
Sbjct: 697 M---------------MQEQEEKMWEQEEKMCEQ----EEKMQEQEEKMRR---QEEKMW 734
Query: 182 KTQVKCRKILTKMKQ 196
+ +V+ R+ KM++
Sbjct: 735 EQEVRLRQQEEKMQE 749
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 47.8 bits (112), Expect = 1e-05
Identities = 43/187 (22%), Positives = 93/187 (49%), Gaps = 27/187 (14%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHK--- 91
EL+S+ ++LQAQ + E N E++ Q+ KIQ+ EE + + ++E K
Sbjct: 261 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 92 -----WGMEQ---GRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKK 143
W E+ ++E+ + ++ LE+ + + E+++ R + ++IR+ +K
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE---EKIREQEK 377
Query: 144 ------FLWEELELVREEVTFIYQK---LQAQEDEISENLVNI----QKMQKTQVKCRKI 190
+W + E +RE+ I ++ +Q QE+++ E + ++MQ+ + K R+
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 191 LTKMKQQ 197
K+++Q
Sbjct: 438 EEKIREQ 444
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/212 (22%), Positives = 89/212 (41%), Gaps = 23/212 (10%)
Query: 27 DSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLE-EVLSPTGRQG 85
D QK E+L+ +L+AQ + L T L+ Q ++QLE E R
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 156
Query: 86 EKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFL 145
+ + +EQ AL+ +K R EE+ + R L+L I D
Sbjct: 157 DSWKFAGELEQ-------ALSAVATQKKKADRYIEELTKERDALSLELYRNTITD----- 204
Query: 146 WEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACP 205
E ++E+ + +KLQ E E SE +N++++++ + + +L + + Q
Sbjct: 205 ----EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 260
Query: 206 ETEEIPQGASGCWKDDLQKELSDIWSAVHVLQ 237
E + + K Q E +++W+ ++ Q
Sbjct: 261 ELQSVSA------KLQAQVEENELWNRLNQQQ 286
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/203 (21%), Positives = 91/203 (44%), Gaps = 42/203 (20%)
Query: 29 QKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTG-RQGEK 87
Q+ R E E ++ Q + Q + + + E+E KI++ EE++ + GE+
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE-----KIREQEEMMQEQEEKMGEQ 416
Query: 88 EEHKWGMEQGRQELYGALTQGLQGL----------EKTLRDSEEMQRARTTRC------- 130
EE W E+ QE + + + + E+ +R+ EEM + + +
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 131 -------------LQLLAQEIRDSKKFLWEELELVREEVTFIYQ---KLQAQEDEISENL 174
++ ++IR+ +K + E+ E +RE+ + + K+ QE+++ E
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536
Query: 175 VNIQKMQKTQVKCRKILTKMKQQ 197
+KMQ+ + K R+ KM++Q
Sbjct: 537 ---EKMQEQEEKMRRQEEKMREQ 556
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/177 (20%), Positives = 90/177 (50%), Gaps = 19/177 (10%)
Query: 25 IPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTML-EKESCLQQIKIQQLEEVLSPTGR 83
I + ++ +R + E ++ Q + + E + M+ EKE +++++ + E+
Sbjct: 304 IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 363
Query: 84 QGEKEEHKWGMEQGRQELYGAL---TQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRD 140
+ +EE K ++ RQE + + ++ E+ +R+ EEM +Q +++ +
Sbjct: 364 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM--------MQEQEEKMGE 415
Query: 141 SKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQ 197
++ +WE+ E ++E+ +K++ QE++I E +K+++ + K R+ M++Q
Sbjct: 416 QEEKMWEQEEEMQEQ----EEKMRRQEEKIRE---QEKKIREQEEKIREQEEMMQEQ 465
Score = 38.1 bits (87), Expect = 0.009
Identities = 40/197 (20%), Positives = 93/197 (47%), Gaps = 21/197 (10%)
Query: 6 QVKPLETSSSKVKAKTIVMIPDSQKLLRCE--LESLKSQLQAQTKAFEFLNHSVTMLEKE 63
Q + + K++ + +M +K+ E + + ++Q Q + + EK+
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 64 SCLQQIKIQQLEEVLSPTG-RQGEKEEHKWGME---QGRQELYGALTQGLQGLEKTLRDS 119
Q+ KI++ EE++ + GE+E E Q ++E + ++ EK +R+
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 120 EEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQK 179
EE R + + +++ ++ +WE+ E + E+ +K+Q QE+++ +K
Sbjct: 508 EEKIREQE--------EMMQEQEEKMWEQEEKMCEQE----EKMQEQEEKMRRQE---EK 552
Query: 180 MQKTQVKCRKILTKMKQ 196
M++ +V+ R+ KM++
Sbjct: 553 MREQEVRLRQQEEKMQE 569
Score = 31.6 bits (70), Expect = 0.88
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 30/174 (17%)
Query: 36 LESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGME 95
+ES KS++Q K + LE+ L + QQL+ G++ + K +
Sbjct: 221 VESEKSEIQLNVKELK------RKLERAKLL--LPQQQLQAEADHLGKELQSVSAKLQAQ 272
Query: 96 QGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREE 155
EL+ L Q Q EK R E++Q R+ K + E+ E +RE+
Sbjct: 273 VEENELWNRLNQ--QQEEKMWRQEEKIQE--------------REEK--IQEQEEKIREQ 314
Query: 156 VTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEE 209
+K++ QE+ + E +++ ++ + + + +++++ HE E EE
Sbjct: 315 E----EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.6 bits (109), Expect = 3e-05
Identities = 60/241 (24%), Positives = 104/241 (43%), Gaps = 16/241 (6%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
E++ ++ +KV+ + M Q+LL E L QLQA+T+ F E+
Sbjct: 859 EELLKVKEKQTKVEGELEEMERKHQQLLE-EKNILAEQLQAETELF-------AEAEEMR 910
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQR 124
K Q+LEE+L + E+EE + + Q ++ + +Q LE+ L D EE R
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKK---KMQAHIQDLEEQL-DEEEGAR 966
Query: 125 ARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQ 184
+ LQL K + EE+ L+ ++ + ++ + ED I+E + + ++
Sbjct: 967 QK----LQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA 1022
Query: 185 VKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKELSDIWSAVHVLQNSIDSLT 244
KI K + + + EE + K L E +D+ + LQ ID L
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 245 L 245
L
Sbjct: 1083 L 1083
Score = 37.7 bits (86), Expect = 0.012
Identities = 59/283 (20%), Positives = 116/283 (40%), Gaps = 47/283 (16%)
Query: 5 EQVKPLETSSSKVKAK------TIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVT 58
+QV L++ + K K TI + +++K L + E+L +L+ + A++ L +
Sbjct: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
Query: 59 MLEKESCLQQIKIQQLEEVLSPTGRQGEK----------------EEHKWGMEQGRQELY 102
L++E + + +V S ++ +K EE + R++
Sbjct: 1424 RLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483
Query: 103 GALTQGLQGLEKTLRDSEEMQRARTTRCLQLL------------AQEIRDSKKFLWEELE 150
AL+ + LE+ L EE +R + E+ SK+ L +++E
Sbjct: 1484 KALSLA-RALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE 1542
Query: 151 LVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQ----------QGHE 200
+R ++ + +LQA ED VN+Q M K Q + R + T+ +Q Q E
Sbjct: 1543 EMRTQLEELEDELQATEDAKLRLEVNMQAM-KAQFE-RDLQTRDEQNEEKKRLLIKQVRE 1600
Query: 201 TAACPETEEIPQGASGCWKDDLQKELSDIWSAVHVLQNSIDSL 243
A E E + + K ++ +L D+ + + + D +
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV 1643
Score = 35.4 bits (80), Expect = 0.061
Identities = 58/261 (22%), Positives = 109/261 (41%), Gaps = 32/261 (12%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFE--FLNHSVTML 60
E + + LE + K+ +T + D L+ +++ LK QL + + + L
Sbjct: 1046 EEKTRQELEKAKRKLDGET-TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETL 1104
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGR---QELYGALTQGLQGLEKTLR 117
K + L+ ++ Q + + EK +Q R +EL T+ LE TL
Sbjct: 1105 HKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE----LEDTLD 1160
Query: 118 DSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENL--- 174
+ Q RT R QE+ + KK L EE + ++ + Q+ +E+SE L
Sbjct: 1161 TTAAQQELRTKR-----EQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA 1215
Query: 175 ----VNIQKMQK------TQVKCR-KILTKMKQQGHETAACPETEEIPQGASGCWKDDLQ 223
N++K ++ ++ C K+L ++K + + + A D L+
Sbjct: 1216 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLR 1275
Query: 224 KELSDIWSAVHVLQNSIDSLT 244
EL++ S LQN +D+++
Sbjct: 1276 VELAEKASK---LQNELDNVS 1293
Score = 28.5 bits (62), Expect = 7.4
Identities = 29/162 (17%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
Query: 24 MIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGR 83
++ D + ++++L ++L A+ A + +++ LE+++ + K+Q+LE +
Sbjct: 1754 LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV----- 1808
Query: 84 QGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKK 143
K + K + ++ G L + L+ K + ++ R RT + L+ + ++ D ++
Sbjct: 1809 ---KSKFKATISALEAKI-GQLEEQLEQEAKERAAANKLVR-RTEKKLKEIFMQVEDERR 1863
Query: 144 F---LWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQK 182
E++E + + ++L+ E+E + + +K+Q+
Sbjct: 1864 HADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 45.8 bits (107), Expect = 5e-05
Identities = 37/140 (26%), Positives = 73/140 (52%), Gaps = 11/140 (7%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
E++ Q+ KI++ EE + Q EK + M Q ++E G + +Q EK R E
Sbjct: 515 EEKMWRQEEKIREQEEKIR---EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE 571
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIY---QKLQAQEDEISENLVNI 177
+++ ++ ++IR+ ++ +WE+ E +RE+ + +K+ QE+++ E
Sbjct: 572 KIREQEEK--IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE---QE 626
Query: 178 QKMQKTQVKCRKILTKMKQQ 197
+KMQ+ + K R+ KM +Q
Sbjct: 627 EKMQEQEEKMRRQEEKMWEQ 646
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/167 (24%), Positives = 86/167 (51%), Gaps = 15/167 (8%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGM 94
EL+S+ ++LQAQ + E N E++ Q+ KIQ+ EE + Q ++E+ +
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI-----QEQEEKIREQE 327
Query: 95 EQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR- 153
E+ R++ + ++ E+ + + EE R R + +++R ++ +WE+ E +R
Sbjct: 328 EKIREQ-----EEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEKMRRLEEMMWEKEEKIRE 381
Query: 154 -EEVTFIYQKLQAQED--EISENLVNIQKMQKTQVKCRKILTKMKQQ 197
EE +K++ QE+ + E + +K Q+ + K + K+++Q
Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/224 (22%), Positives = 93/224 (41%), Gaps = 38/224 (16%)
Query: 27 DSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLE-EVLSPTGRQG 85
D QK E+L+ +L+AQ L T L+ Q ++QLE E R
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 168
Query: 86 EKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLA-----QEIRD 140
+ + +EQ AL+ +K R EE+ + R L+L +E+++
Sbjct: 169 DSWKFAGELEQ-------ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
Query: 141 SKKFLWEELELVREEVTFI-------------------YQKLQAQEDEISENLVNIQKMQ 181
L E+L+LV E + I Q+LQA+ D + + L ++
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 182 KTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKE 225
+ QV+ ++ ++ QQ E + E+I + W++ +Q++
Sbjct: 282 QAQVEENELWNRLNQQ-QEEKMWRQEEKIQE-----WEEKIQEQ 319
Score = 35.8 bits (81), Expect = 0.047
Identities = 37/195 (18%), Positives = 91/195 (46%), Gaps = 32/195 (16%)
Query: 25 IPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTML-EKESCLQQI---------KIQQL 74
I + ++ +R + E ++ Q + + E + M+ EKE ++++ KI++L
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 75 EEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLL 134
EE + + E+EE + E+ R++ EK R +E + R ++
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQ------------EK--RQEQEAKMWRQEEKIREQ 428
Query: 135 AQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKM 194
++IR+ +K +W + E + E+ ++ + +++E+ Q+ +++ ++ + +
Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR--------QEEKIREQEEIWRQ 480
Query: 195 KQQGHETAACPETEE 209
K++ HE + EE
Sbjct: 481 KEKMHEQEKIRKQEE 495
Score = 29.6 bits (65), Expect = 3.3
Identities = 42/206 (20%), Positives = 92/206 (44%), Gaps = 29/206 (14%)
Query: 4 HEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKE 63
HEQ K + KV + M +K+ E + + + + + + + + E+E
Sbjct: 485 HEQEK-IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 64 SCLQQI--KIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGL---EKTLRD 118
+Q+ K+ + EE + + +EE E+ +E + + + + E+ +R+
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 119 SEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQ 178
EEM +++ ++ +WE+ E + E+ +K+Q QE+++ +
Sbjct: 604 QEEM---------------MQEQEEKMWEQEEKMCEQ----EEKMQEQEEKMRR---QEE 641
Query: 179 KMQKTQVKCRKILTKMKQ-QGHETAA 203
KM + +V+ R+ KM++ Q H AA
Sbjct: 642 KMWEQEVRLRQQEEKMQEHQEHLEAA 667
>gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens]
Length = 448
Score = 45.8 bits (107), Expect = 5e-05
Identities = 54/218 (24%), Positives = 96/218 (44%), Gaps = 49/218 (22%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEK 62
+HE V ++ + K +K +V + EL+ L+SQL A
Sbjct: 266 KHEAVMNVKKQTQKGNSKKVVQMEQ-------ELQDLQSQLCA----------------- 301
Query: 63 ESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGME--QGRQELYGALTQGLQGLEKTLRDSE 120
E QQ +++QLE+ E+E+H G+E QG ++L L Q LQ + E
Sbjct: 302 EQAQQQARVEQLEKTFQ------EEEQHLQGLEIAQGEKDLKQQLAQALQEHWALM---E 352
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM 180
E+ R++ + I +K +ELE +EE +K+QAQ++E+ ++ ++ +
Sbjct: 353 ELNRSKKD------FEAIIQAKN---KELEQTKEE----KEKMQAQKEEVLSHMNDVLEN 399
Query: 181 QKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCW 218
+ + C + + + E A E +P AS W
Sbjct: 400 ELQCIICSEYFIEQRDCS-EDRALRAFERLPGSASLRW 436
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 45.8 bits (107), Expect = 5e-05
Identities = 62/272 (22%), Positives = 111/272 (40%), Gaps = 41/272 (15%)
Query: 27 DSQKLLRCELESLKSQLQ-AQTKAFEFLNHSVTMLEKESCLQQIK------IQQLEEVLS 79
+ ++LL E+ SL QLQ +T+ + H + E++ L Q K + LE +
Sbjct: 499 EEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAG 558
Query: 80 PTGRQ----GEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRD-------SEEMQRARTT 128
P G + GEK E + QE +G + +GL++ D S+E + +
Sbjct: 559 PPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQAN 618
Query: 129 RCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQ---------- 178
R L+ Q + + L +L+ ++ + YQ LQ +E I +L +++
Sbjct: 619 RELEKELQNVVGRNQLLEGKLQALQAD----YQALQQRESAIQGSLASLEAEQASIRHLG 674
Query: 179 -KMQKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKELSDIWSAVHVLQ 237
+M+ + + RK MK Q E A +++E C L++E+
Sbjct: 675 DQMEASLLAVRKAKEAMKAQMAEKEAILQSKE-----GEC--QQLREEVEQCQQLAEARH 727
Query: 238 NSIDSL-TLCSGACPKASSLRGHKGHQCLSPP 268
+ +L + C L KG Q + PP
Sbjct: 728 RELRALESQCQQQTQLIEVLTAEKGQQGVGPP 759
Score = 32.7 bits (73), Expect = 0.39
Identities = 48/185 (25%), Positives = 93/185 (50%), Gaps = 26/185 (14%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGM 94
E++ L +LQA L T +E+ + Q +++QL + L KE+ + +
Sbjct: 399 EMQELGEKLQA-------LERERTKVEEVNRQQSAQLEQLVKELQL------KEDARASL 445
Query: 95 EQGRQELYGALTQGLQG----LEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELE 150
E+ +E+ L + L G ++ R +E+ A T+ + LA E+R KK EE E
Sbjct: 446 ERLVKEM-APLQEELSGKGQEADQLWRRLQELL-AHTSSWEEELA-ELRREKKQQQEEKE 502
Query: 151 LVREEVTFIYQKLQ---AQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGH-ETAACPE 206
L+ +EV + ++LQ Q ++S+++ ++++ +K ++ + L+ +Q G E A P
Sbjct: 503 LLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLS--QQVGMLERLAGPP 560
Query: 207 TEEIP 211
E+P
Sbjct: 561 GPELP 565
Score = 31.2 bits (69), Expect = 1.1
Identities = 36/180 (20%), Positives = 77/180 (42%), Gaps = 40/180 (22%)
Query: 25 IPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQ-------LEEV 77
+ D Q +R L+ + ++Q+Q E + E ++ +QQ+K Q ++E+
Sbjct: 792 VVDLQAKMRAALDD-QDKVQSQLSMAE-----AVLREHKTLVQQLKEQNEALNRAHVQEL 845
Query: 78 LSPTGRQGEKEEHKWGMEQGRQELYGALTQGL------------------QGLEKTLRDS 119
L + R+G +E + Q R+E AL + L + L + D+
Sbjct: 846 LQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDT 905
Query: 120 EEM---------QRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEI 170
E+ ++ R L QE++D+K+ E E + +V + Q+ ++ ++++
Sbjct: 906 AELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKL 965
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 45.4 bits (106), Expect = 6e-05
Identities = 41/167 (24%), Positives = 86/167 (51%), Gaps = 15/167 (8%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGM 94
EL+S+ ++LQAQ + E N E++ Q+ KIQ+ EE + Q ++E+ +
Sbjct: 334 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI-----QEQEEKIREQE 388
Query: 95 EQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR- 153
E+ R++ + ++ E+ + + EE R R + +++R ++ +WE+ E +R
Sbjct: 389 EKIREQ-----EEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442
Query: 154 -EEVTFIYQKLQAQED--EISENLVNIQKMQKTQVKCRKILTKMKQQ 197
EE +K++ QE+ + E + +K Q+ + K + K+++Q
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/224 (22%), Positives = 93/224 (41%), Gaps = 38/224 (16%)
Query: 27 DSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLE-EVLSPTGRQG 85
D QK E+L+ +L+AQ L T L+ Q ++QLE E R
Sbjct: 170 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 229
Query: 86 EKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLA-----QEIRD 140
+ + +EQ AL+ +K R EE+ + R L+L +E+++
Sbjct: 230 DSWKFAGELEQ-------ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 282
Query: 141 SKKFLWEELELVREEVTFI-------------------YQKLQAQEDEISENLVNIQKMQ 181
L E+L+LV E + I Q+LQA+ D + + L ++
Sbjct: 283 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 342
Query: 182 KTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKE 225
+ QV+ ++ ++ QQ E + E+I + W++ +Q++
Sbjct: 343 QAQVEENELWNRLNQQ-QEEKMWRQEEKIQE-----WEEKIQEQ 380
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/140 (25%), Positives = 71/140 (50%), Gaps = 17/140 (12%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
E++ Q+ KI++ EE + Q EK + M Q ++E G + + E+ +++ E
Sbjct: 577 EEKVWRQEEKIREQEEKIR---EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQ---KLQAQEDEISENLVNI 177
E R + ++IR+ +K + E+ E +RE+ + + K+ QE+++ E
Sbjct: 634 EKMRRQE--------EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE--- 682
Query: 178 QKMQKTQVKCRKILTKMKQQ 197
+KMQ+ + K R+ KM +Q
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQ 702
Score = 34.3 bits (77), Expect = 0.14
Identities = 43/227 (18%), Positives = 93/227 (40%), Gaps = 31/227 (13%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
EQ + + K++ + M + + E + + + K + M EKE
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQR 124
KI++LEE + + E+EE + E+ R++ EK R +E +
Sbjct: 439 -----KIRELEEKMHEQEKIREQEEKRQEEEKIREQ------------EK--RQEQEAKM 479
Query: 125 ARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNI------- 177
R ++ ++IR+ ++ +W + E + E+ ++ + +++E+ I
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 178 ---QKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDD 221
+K+ + + K RK KM +Q E + E+I + W+ +
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQ--EEKMHDQEEKIREQEEKVWRQE 584
Score = 33.9 bits (76), Expect = 0.18
Identities = 47/203 (23%), Positives = 92/203 (45%), Gaps = 49/203 (24%)
Query: 4 HEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKE 63
H+Q + + KV + I + ++ +R + E ++ Q + + E + E++
Sbjct: 567 HDQEEKIREQEEKVWRQE-EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ----EEK 621
Query: 64 SCLQQIKIQQLEEVLSPTGRQGEK--EEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEE 121
C Q+ K+Q+ EE + RQ EK E+ K EQ E+ +R+ EE
Sbjct: 622 MCEQEEKMQEQEEKMR---RQEEKIREQEKKIREQ----------------EEKIREQEE 662
Query: 122 MQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQ 181
M +++ ++ +WE+ E + E+ +K+Q QE+++ +KM
Sbjct: 663 M---------------MQEQEEKMWEQEEKMCEQ----EEKMQEQEEKMRR---QEEKMW 700
Query: 182 KTQVKCRKILTKMKQ-QGHETAA 203
+ +V+ R+ KM++ Q H AA
Sbjct: 701 EQEVRLRQQEEKMQEHQEHLEAA 723
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/219 (25%), Positives = 106/219 (48%), Gaps = 20/219 (9%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEK 62
+++ KP + V + + + D K LR E+E L+ +LQ+Q + N ++++L K
Sbjct: 279 KNQMAKPPSLAPPAVTS-VVEQLQDEAKHLRQEVEGLEGKLQSQVEN----NQALSLLSK 333
Query: 63 ESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGR----QELYGALTQGLQGLEKTLRD 118
E Q+ ++Q+ EE+L Q +E+ + + R Q+ + L+ E+ LR
Sbjct: 334 E---QKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRK 390
Query: 119 SEEMQRARTTRCLQLLAQEIRDSKKFLWEELELV--REEVTFIYQ--KLQAQ--EDEISE 172
EE R R LQ + + D ++ LW++ E + +EE + Q KL Q E + S
Sbjct: 391 QEERLRKEEER-LQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSF 449
Query: 173 NLVNIQKMQKTQVKCR-KILTKMKQQGHETAACPETEEI 210
+N +K Q++ + K L + + H AA + +++
Sbjct: 450 EDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQL 488
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.1 bits (105), Expect = 8e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 20/189 (10%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGL---EKTLR 117
EKE Q+ ++++ +E+ + E+EE W E+ +E + + + L EK +R
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 118 DSEEMQRARTTRC------LQLLAQEIRDSKKFLWEELELVREEVTFIYQ--KLQAQEDE 169
+ E+ R + R L+ + +R+ +K +WE++E +REE Q K + QE++
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEK-MWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 170 ISEN---LVNIQKMQKTQVKCRKILTKMKQQGHETAACPETE----EIPQGASGCWKDD- 221
+ E +KM++ + R+ KM++Q E E +P+ W+ +
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 222 LQKELSDIW 230
+Q++ IW
Sbjct: 506 MQEQEEKIW 514
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/250 (22%), Positives = 108/250 (43%), Gaps = 37/250 (14%)
Query: 6 QVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFL--------NHSV 57
Q + +T + K + I + +K +R E E+++ Q + K E +
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 58 TMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQG--RQELYGALTQGLQGLEKT 115
+KE +Q K+Q+ EE + + +E WG E+ RQE + E+
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 116 LRDSEEM--------------QRARTTRCLQLLAQE--IRDSKKFLWEELELVREEVTFI 159
+RD E+ Q +T + + +E +R+ +K + EE E++RE+
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ---- 608
Query: 160 YQKLQAQEDEISENLVNI----QKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQGAS 215
+K+Q QE+++ E + +KMQ+ + K + KM +Q + E + +P+
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW---EQQRLPEQKE 665
Query: 216 GCWKDDLQKE 225
W+ + +E
Sbjct: 666 KLWEHEKMQE 675
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/214 (20%), Positives = 99/214 (46%), Gaps = 33/214 (15%)
Query: 27 DSQKLLRCELESLKSQ---LQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGR 83
+ ++++R + E ++ Q +Q Q + + E++ Q+ K+ + EE + R
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Query: 84 QGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQE------ 137
E++E W E+ +++ + +Q E+ + + E+M++ + + QE
Sbjct: 660 LPEQKEKLWEHEKMQEQ------EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 138 -IRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQ 196
+R+ +K + EE E++RE+ +K+Q QE +KMQ+ + + + KM +
Sbjct: 714 SMREREKKMREEEEMMREQ----EEKMQEQE----------EKMQEQEEEMWEQEEKMWE 759
Query: 197 QGHETAACPETEEIPQGASGCWKDDLQKELSDIW 230
Q + E + +P+ W+ + +E IW
Sbjct: 760 QEEKMW---EQQRLPEQKEKLWEHEKMQEQEKIW 790
Score = 31.6 bits (70), Expect = 0.88
Identities = 28/137 (20%), Positives = 63/137 (45%), Gaps = 22/137 (16%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
+KE + K+Q+ E++ + ++EE G E + ++G E+ +R E
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE-----------EKMRGQEEKMRGQE 821
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM 180
E + +++ ++ +W + E + + + +K+Q QE+++ E +KM
Sbjct: 822 EKMWGQ--------EEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE---QEEKM 870
Query: 181 QKTQVKCRKILTKMKQQ 197
+ + K R+ KM+ Q
Sbjct: 871 RGQEEKMREQEEKMRGQ 887
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.1 bits (105), Expect = 8e-05
Identities = 51/227 (22%), Positives = 101/227 (44%), Gaps = 29/227 (12%)
Query: 25 IPDSQKLLRCELESLKSQLQAQTKAFEFL--------NHSVTMLEKESCLQQIKIQQLEE 76
I + +K +R E E+++ Q + K E + +KE +Q K+Q+ EE
Sbjct: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
Query: 77 VLSPTGRQGEKEEHKWGMEQ--GRQELYGALTQGLQGLEKTLRDSEEMQRARTTRC---- 130
+ + +E WG E+ RQE + E+ +RD E+ + R
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513
Query: 131 --LQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEI---SENLVNIQKMQKTQV 185
L+ + +R+ KK +W++ E +REE +K Q QE + E + ++M++ +
Sbjct: 514 ERLREKEERMREQKK-MWQQEEKMREE-----KKTQEQEKKTWDQEEKMREEERMREREK 567
Query: 186 KCRKILTKMKQQGHETAACPETEEIPQGASGCWKDD--LQKELSDIW 230
K R+ M++Q E + E++ + W+ + +Q++ +W
Sbjct: 568 KMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Score = 40.0 bits (92), Expect = 0.002
Identities = 50/237 (21%), Positives = 104/237 (43%), Gaps = 31/237 (13%)
Query: 6 QVKPLETSSSKVKAKTIVMIPDSQKLLRCE--LESLKSQLQAQTKAFEFLNHSVTMLEKE 63
Q + L K++ + M ++L E + + +++ Q K + EKE
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 64 SCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQ 123
+Q K+++ EE + E+EE W E+ +E + + E+ L + E+
Sbjct: 299 -LREQKKLREQEEQMQ------EQEEKMWEQEEKMREQ----EEKMWRQEERLWEQEKQM 347
Query: 124 RARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFI--YQKLQAQEDEISEN---LVNIQ 178
R + Q++RD ++ +WE+ E +RE+ + +K+ QE+++ E +
Sbjct: 348 REQE--------QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 179 KMQKTQVKCRKILTKMKQQGHETAACPETE----EIPQGASGCWKDD-LQKELSDIW 230
KM++ + R+ KM++Q E E +P+ W+ + +Q++ IW
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Score = 39.3 bits (90), Expect = 0.004
Identities = 44/196 (22%), Positives = 90/196 (45%), Gaps = 21/196 (10%)
Query: 37 ESLKSQLQAQTKAFEFLNHSVTMLEKE---SCLQQIKIQQLEEVLSPTGRQGEKEEHKWG 93
ES KS++Q K + L + + LQ+ +Q EE+ + ++EE W
Sbjct: 200 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 259
Query: 94 MEQGRQELYGAL---TQGLQGLEKTLRDSEEMQR-----ARTTRCLQLLAQEIRDSKKFL 145
E+ +E G + + ++ EK LR+ E+ R R + L+ +++++ ++ +
Sbjct: 260 QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
Query: 146 WEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACP 205
WE+ E +RE+ +K+ QE+ + E ++M++ + K R +M +Q
Sbjct: 320 WEQEEKMREQ----EEKMWRQEERLWE---QEKQMREQEQKMRDQEERMWEQDERLR--- 369
Query: 206 ETEEIPQGASGCWKDD 221
E EE + W+ +
Sbjct: 370 EKEERMREQEKMWEQE 385
Score = 36.2 bits (82), Expect = 0.036
Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 27/161 (16%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSE 120
++E +Q K+ Q EE + + E+E+ W E+ +E + ++ EK +R+ E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-----EERMREREKKMREEE 573
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM 180
EM +R+ ++ + E+ E +RE+ +K+ QE+++ E +KM
Sbjct: 574 EM---------------MREQEEKMQEQEEKMREQ----EEKMWEQEEKMQE---QEEKM 611
Query: 181 QKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDD 221
+ + K + + K Q E + E++ + W+ +
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Score = 35.8 bits (81), Expect = 0.047
Identities = 35/165 (21%), Positives = 76/165 (46%), Gaps = 12/165 (7%)
Query: 61 EKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGL----EKTL 116
EK++ Q+ K+++ E + + E+EE E+ QE + + + + EK
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
Query: 117 RDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIY---QKLQAQEDEISEN 173
E+M Q ++++ ++ +WE+ E ++E+ ++ +K++ QE+++ E
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE- 664
Query: 174 LVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCW 218
+KMQ + K R+ + K QG E + E++ W
Sbjct: 665 --QEEKMQGQEEKMRE--QEEKMQGQEEKMREQEEKMRGQEEKMW 705
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 45.1 bits (105), Expect = 8e-05
Identities = 53/200 (26%), Positives = 98/200 (49%), Gaps = 19/200 (9%)
Query: 22 IVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPT 81
+ + D K LR E+E L+ +LQ+Q + N ++++L KE Q+ ++Q+ EE+L
Sbjct: 297 VEQLQDEAKHLRQEVEGLEGKLQSQVEN----NQALSLLSKE---QKQRLQEQEEMLREQ 349
Query: 82 GRQGEKEEHKWGMEQGR----QELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQE 137
Q +E+ + + R Q+ + L+ E+ LR EE R R LQ +
Sbjct: 350 EAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEER-LQKQEKR 408
Query: 138 IRDSKKFLWEELELV--REEVTFIYQ--KLQAQ--EDEISENLVNIQKMQKTQVKCR-KI 190
+ D ++ LW++ E + +EE + Q KL Q E + S +N +K Q++ + K
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 191 LTKMKQQGHETAACPETEEI 210
L + + H AA + +++
Sbjct: 469 LQEKLDEEHLEAASHQNQQL 488
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/200 (26%), Positives = 97/200 (48%), Gaps = 19/200 (9%)
Query: 22 IVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPT 81
+ + D K LR E+E L+ +LQ+Q + N ++++L KE Q+ ++Q+ EE+L
Sbjct: 297 VEQLQDEAKHLRQEVEGLEGKLQSQVEN----NQALSLLSKE---QKQRLQEQEEMLREQ 349
Query: 82 GRQGEKEEHKWGMEQGR----QELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQE 137
Q +E+ + + R Q+ + L+ E+ LR EE R R LQ +
Sbjct: 350 EAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEER-LQKQEKR 408
Query: 138 IRDSKKFLWEELELV--REEVTFIYQ--KLQAQ--EDEISENLVNIQKMQKTQVKCR-KI 190
+ D ++ LW++ E + +EE + Q KL Q E + S +N +K Q++ + K
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 191 LTKMKQQGHETAACPETEEI 210
L + + H AA +++
Sbjct: 469 LQEKLDEEHLEAASQRNQQL 488
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/200 (26%), Positives = 97/200 (48%), Gaps = 19/200 (9%)
Query: 22 IVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPT 81
+ + D K LR E+E L+ +LQ+Q + N ++++L KE Q+ ++Q+ EE+L
Sbjct: 297 VEQLQDEAKHLRQEVEGLEGKLQSQVEN----NQALSLLSKE---QKQRLQEQEEMLREQ 349
Query: 82 GRQGEKEEHKWGMEQGR----QELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQE 137
Q +E+ + + R Q+ + L+ E+ LR EE R R LQ +
Sbjct: 350 EAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEER-LQKQEKR 408
Query: 138 IRDSKKFLWEELELV--REEVTFIYQ--KLQAQ--EDEISENLVNIQKMQKTQVKCR-KI 190
+ D ++ LW++ E + +EE + Q KL Q E + S +N +K Q++ + K
Sbjct: 409 LWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKE 468
Query: 191 LTKMKQQGHETAACPETEEI 210
L + + H AA +++
Sbjct: 469 LQEKLDEEHLEAASQRNQQL 488
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 43.5 bits (101), Expect = 2e-04
Identities = 44/227 (19%), Positives = 105/227 (46%), Gaps = 39/227 (17%)
Query: 1 MGEHEQVKPLETSSSKVKAKTIVMIPDSQKL-------LRCELESLKSQLQAQTKAFEFL 53
M ++E+++ LET+ + K + ++K+ + ++E L++QL+ + + F+
Sbjct: 728 MEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQ 787
Query: 54 NHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHK---------------------- 91
+++ML+++ +Q ++ L+ +L+ + + +KE K
Sbjct: 788 EKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQL 847
Query: 92 -WGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELE 150
+E ++EL L Q L+G K + + +++ CLQ +E++ L E
Sbjct: 848 DSALEICKEELVLHLNQ-LEG-NKEKFEKQLKKKSEEVYCLQ---KELKIKNHSLQE--- 899
Query: 151 LVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQ 197
E+ + LQ Q+ + + + +++ TQ K K ++K++Q+
Sbjct: 900 -TSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQE 945
Score = 34.7 bits (78), Expect = 0.10
Identities = 40/197 (20%), Positives = 83/197 (42%), Gaps = 30/197 (15%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQL-------------QAQTKAFE 51
+++K L +K++ + ++ + L+ + ES+ +L Q Q +
Sbjct: 229 QEIKSLREKLNKLRQQNACLVTQNHSLMT-KFESIHFELTQSRAKVSMLESAQQQAASVP 287
Query: 52 FLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQG 111
L + LE E Q +++ E L + + ++E +++ ++E L+
Sbjct: 288 ILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQS--LQESKEECIKLKVDLLEQ 345
Query: 112 LEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEIS 171
++ R E QR + L++ + KK + E+LE K+QA+E+ +
Sbjct: 346 TKQGKR--AERQRNEALYNAEELSKAFQQYKKKVAEKLE-----------KVQAEEEILE 392
Query: 172 ENLVNIQKMQK-TQVKC 187
NL N +K K Q +C
Sbjct: 393 RNLTNCEKENKRLQERC 409
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 43.1 bits (100), Expect = 3e-04
Identities = 59/252 (23%), Positives = 109/252 (43%), Gaps = 38/252 (15%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPD---SQKLLRCELESLKSQLQAQTKAFEFLNHSVTM 59
E E+VK L K +A TI + D ++ R ELE LK +L ++
Sbjct: 1043 EEEKVKSLNKLRLKYEA-TIADMEDRLRKEEKGRQELEKLKRRLDGESSE---------- 1091
Query: 60 LEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQ----GRQELYGALTQGLQGLEKT 115
L+++ QQ Q+ EE+ + GR+ E+ + + R +L +L + L +
Sbjct: 1092 LQEQMVEQQ---QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1148
Query: 116 LRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLV 175
D E + ART + ++ L EELE +R E+ AQ++ S+
Sbjct: 1149 QEDLESERVART---------KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 1199
Query: 176 NIQKMQKT---QVKCRKILTKMKQQGHETAACPETEEIPQG--ASGCWKDD---LQKELS 227
+ +++KT + + + + +Q H A E++ Q G W+ L+ E+S
Sbjct: 1200 EVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1259
Query: 228 DIWSAVHVLQNS 239
++ + + LQ +
Sbjct: 1260 ELRAELSSLQTA 1271
Score = 32.0 bits (71), Expect = 0.67
Identities = 42/172 (24%), Positives = 78/172 (45%), Gaps = 19/172 (11%)
Query: 30 KLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEE 89
+ LR ELE+L S K+ L + + E+ + + ++ +LE+ L+ E+
Sbjct: 1532 RALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA------ED 1585
Query: 90 HKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
K +E Q L + LQG RD +R R LA+++RD++ EE
Sbjct: 1586 AKLRLEVTVQALKTQHERDLQG-----RDEAGEERRRQ------LAKQLRDAEVERDEER 1634
Query: 150 ELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK-CRKILTKMKQQGHE 200
+ R +KL+ + +E+ + + + ++ VK RK+ +MK+ E
Sbjct: 1635 K-QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1685
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 43.1 bits (100), Expect = 3e-04
Identities = 59/252 (23%), Positives = 109/252 (43%), Gaps = 38/252 (15%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPD---SQKLLRCELESLKSQLQAQTKAFEFLNHSVTM 59
E E+VK L K +A TI + D ++ R ELE LK +L ++
Sbjct: 1035 EEEKVKSLNKLRLKYEA-TIADMEDRLRKEEKGRQELEKLKRRLDGESSE---------- 1083
Query: 60 LEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQ----GRQELYGALTQGLQGLEKT 115
L+++ QQ Q+ EE+ + GR+ E+ + + R +L +L + L +
Sbjct: 1084 LQEQMVEQQ---QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1140
Query: 116 LRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLV 175
D E + ART + ++ L EELE +R E+ AQ++ S+
Sbjct: 1141 QEDLESERVART---------KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 1191
Query: 176 NIQKMQKT---QVKCRKILTKMKQQGHETAACPETEEIPQG--ASGCWKDD---LQKELS 227
+ +++KT + + + + +Q H A E++ Q G W+ L+ E+S
Sbjct: 1192 EVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1251
Query: 228 DIWSAVHVLQNS 239
++ + + LQ +
Sbjct: 1252 ELRAELSSLQTA 1263
Score = 32.0 bits (71), Expect = 0.67
Identities = 42/172 (24%), Positives = 78/172 (45%), Gaps = 19/172 (11%)
Query: 30 KLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEE 89
+ LR ELE+L S K+ L + + E+ + + ++ +LE+ L+ E+
Sbjct: 1524 RALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA------ED 1577
Query: 90 HKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
K +E Q L + LQG RD +R R LA+++RD++ EE
Sbjct: 1578 AKLRLEVTVQALKTQHERDLQG-----RDEAGEERRRQ------LAKQLRDAEVERDEER 1626
Query: 150 ELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK-CRKILTKMKQQGHE 200
+ R +KL+ + +E+ + + + ++ VK RK+ +MK+ E
Sbjct: 1627 K-QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1677
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 43.1 bits (100), Expect = 3e-04
Identities = 59/252 (23%), Positives = 109/252 (43%), Gaps = 38/252 (15%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPD---SQKLLRCELESLKSQLQAQTKAFEFLNHSVTM 59
E E+VK L K +A TI + D ++ R ELE LK +L ++
Sbjct: 1076 EEEKVKSLNKLRLKYEA-TIADMEDRLRKEEKGRQELEKLKRRLDGESSE---------- 1124
Query: 60 LEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQ----GRQELYGALTQGLQGLEKT 115
L+++ QQ Q+ EE+ + GR+ E+ + + R +L +L + L +
Sbjct: 1125 LQEQMVEQQ---QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1181
Query: 116 LRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLV 175
D E + ART + ++ L EELE +R E+ AQ++ S+
Sbjct: 1182 QEDLESERVART---------KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 1232
Query: 176 NIQKMQKT---QVKCRKILTKMKQQGHETAACPETEEIPQG--ASGCWKDD---LQKELS 227
+ +++KT + + + + +Q H A E++ Q G W+ L+ E+S
Sbjct: 1233 EVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1292
Query: 228 DIWSAVHVLQNS 239
++ + + LQ +
Sbjct: 1293 ELRAELSSLQTA 1304
Score = 32.0 bits (71), Expect = 0.67
Identities = 42/172 (24%), Positives = 78/172 (45%), Gaps = 19/172 (11%)
Query: 30 KLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEE 89
+ LR ELE+L S K+ L + + E+ + + ++ +LE+ L+ E+
Sbjct: 1565 RALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA------ED 1618
Query: 90 HKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
K +E Q L + LQG RD +R R LA+++RD++ EE
Sbjct: 1619 AKLRLEVTVQALKTQHERDLQG-----RDEAGEERRRQ------LAKQLRDAEVERDEER 1667
Query: 150 ELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK-CRKILTKMKQQGHE 200
+ R +KL+ + +E+ + + + ++ VK RK+ +MK+ E
Sbjct: 1668 K-QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1718
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 43.1 bits (100), Expect = 3e-04
Identities = 42/196 (21%), Positives = 88/196 (44%), Gaps = 17/196 (8%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKES-CLQQIKIQQLEEVLSPTGRQGEKEEHKWG 93
E + +++++ T+ L+ ++ L KE LQ+ Q L+++ + + + K
Sbjct: 970 EKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTK 1029
Query: 94 MEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR 153
+EQ +L G+L Q EK LR E + + L+L + D +
Sbjct: 1030 LEQQVDDLEGSLEQ-----EKKLRMDLERAKRKLEGDLKLAQESTMD-----------ME 1073
Query: 154 EEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQG 213
+ + +KL+ +E EIS + I+ Q +++ +K + +++ + E E E +
Sbjct: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRA 1133
Query: 214 ASGCWKDDLQKELSDI 229
+ + DL +EL +I
Sbjct: 1134 KAEKQRSDLSRELEEI 1149
Score = 37.4 bits (85), Expect = 0.016
Identities = 39/179 (21%), Positives = 84/179 (46%), Gaps = 34/179 (18%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGM 94
++E LK QL+ +TKA L H++ + L + +Q EE
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLR---EQYEE-----------------E 1353
Query: 95 EQGRQELYGALTQGLQGLE--KTLRDSEEMQRA-RTTRCLQLLAQEIRDSKKFLWEELEL 151
++G+ EL AL++ + +T +++ +QR + LAQ +++++ E +E
Sbjct: 1354 QEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE----EHVEA 1409
Query: 152 VREEVTFIYQKLQAQEDEISENLVNIQK-------MQKTQVKCRKILTKMKQQGHETAA 203
V + + + Q ++E+ + ++++++ + K Q K+L++ KQ+ ET A
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQA 1468
Score = 32.0 bits (71), Expect = 0.67
Identities = 37/186 (19%), Positives = 82/186 (44%), Gaps = 8/186 (4%)
Query: 22 IVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPT 81
+ ++ LL+ E+E L + L+ ++ + +L+ +Q + Q + +
Sbjct: 1674 LAIVERRANLLQAEIEELWATLEQTERSRKIAEQE--LLDASERVQLLHTQNTSLINTKK 1731
Query: 82 GRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTT-----RCLQLLAQ 136
+ + + + +E+ QE A + + + +EE+++ + T R + L Q
Sbjct: 1732 KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 1791
Query: 137 EIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK-CRKILTKMK 195
++D + L E +L + QKL+A+ E+ + N QK VK RK ++K
Sbjct: 1792 TVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVK 1851
Query: 196 QQGHET 201
+ ++T
Sbjct: 1852 ELTYQT 1857
Score = 31.2 bits (69), Expect = 1.1
Identities = 48/228 (21%), Positives = 97/228 (42%), Gaps = 31/228 (13%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQ-GEKEEHKWG 93
E SL ++L +E + L +E+ Q +I L E ++ G+Q E E+ K
Sbjct: 1476 ESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQ 1535
Query: 94 MEQGRQELYGALTQGLQGLE----KTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
+EQ + E+ AL + LE K LR E+ + ++ ++ ++ EE+
Sbjct: 1536 VEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD---------EEI 1586
Query: 150 ELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMK-QQGHETAACPETE 208
+ ++ T + + +Q+ D + + +++K K L +M+ Q H E+
Sbjct: 1587 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKK---KMEGDLNEMEIQLNHANRLAAESL 1643
Query: 209 EIPQGASGCWK-------------DDLQKELSDIWSAVHVLQNSIDSL 243
+ G K +DL+++L+ + ++LQ I+ L
Sbjct: 1644 RNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEEL 1691
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 43.1 bits (100), Expect = 3e-04
Identities = 43/177 (24%), Positives = 85/177 (48%), Gaps = 30/177 (16%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGM 94
++E LK QL+ +TKA L H++ + L + +Q EE Q K E + GM
Sbjct: 1315 QIEELKRQLEEETKAKSTLAHALQSARHDCDLLR---EQYEE------EQEAKAELQRGM 1365
Query: 95 EQGRQELYGALTQ-GLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR 153
+ E+ T+ +++T EE++ A+ + LAQ ++D++ E +E V
Sbjct: 1366 SKANSEVAQWRTKYETDAIQRT----EELEEAK-----KKLAQRLQDAE----EHVEAVN 1412
Query: 154 EEVTFIYQKLQAQEDEISENLVNIQK-------MQKTQVKCRKILTKMKQQGHETAA 203
+ + + Q ++E+ + ++++++ + K Q K+L + KQ+ ET A
Sbjct: 1413 SKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA 1469
Score = 29.3 bits (64), Expect = 4.4
Identities = 46/212 (21%), Positives = 86/212 (40%), Gaps = 29/212 (13%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEK 62
E E+ K E + ++ K K + +K++ E QLQ Q +A + +
Sbjct: 859 EFEKTKE-ELAKTEAKRKEL-----EEKMVTLMQEKNDLQLQVQAEADALAD------AE 906
Query: 63 ESCLQQIKIQ-QLEEVLSPTGRQGEKEEH----KWGMEQGRQELYGALTQGLQGLEKTLR 117
E C Q IK + QLE + + E EE ++ ++ L + + LE TL
Sbjct: 907 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 118 DSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNI 177
E+ + A + K L EE+ + E + + ++ +A ++ + L ++
Sbjct: 967 KVEKEKHATENKV------------KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL 1014
Query: 178 QKMQKTQVKCRKILTKMKQQGHETAACPETEE 209
Q + K TK++QQ + E E+
Sbjct: 1015 QMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEK 1046
Score = 29.3 bits (64), Expect = 4.4
Identities = 54/277 (19%), Positives = 107/277 (38%), Gaps = 41/277 (14%)
Query: 4 HEQ-VKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEK 62
H+Q + L+ KV T ++ L +++ L+ L+ + K L + LE
Sbjct: 1007 HQQTLDDLQMEEDKVNTLT-----KAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEG 1061
Query: 63 ESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQ------------ 110
+ L Q E + +K+E + QG+ E AL LQ
Sbjct: 1062 DLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEE 1121
Query: 111 -----GLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR------------ 153
E+ R E QR+ +R L+ +++ + ++ ++E+ +
Sbjct: 1122 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1181
Query: 154 -EEVTFIYQKLQA-----QEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPET 207
EE T ++ A D ++E I +Q+ + K K +++K + ++ A+ ET
Sbjct: 1182 LEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMET 1241
Query: 208 EEIPQGASGCWKDDLQKELSDIWSAVHVLQNSIDSLT 244
+ L+ +LS+I + Q I+ L+
Sbjct: 1242 VSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELS 1278
Score = 28.5 bits (62), Expect = 7.4
Identities = 50/225 (22%), Positives = 93/225 (41%), Gaps = 25/225 (11%)
Query: 35 ELESLKSQLQAQTKAFE-FLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQ-GEKEEHKW 92
E SL ++L A+E L+H T+ + LQQ +I L E ++ G+ E E+ K
Sbjct: 1477 ESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQ-EISDLTEQIAEGGKHIHELEKVKK 1535
Query: 93 GMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELV 152
++ + EL +L + LE EE + R L + EI EEL+ +
Sbjct: 1536 QLDHEKSELQTSLEEAEASLE-----HEEGKILRIQLELNQVKSEIDRKIAEKDEELDQL 1590
Query: 153 REEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMK-QQGHETAACPETEEIP 211
+ + + +Q+ D + + +++K K L +M+ Q H E
Sbjct: 1591 KRNHLRVVESMQSTLDAEIRSRNDALRIKK---KMEGDLNEMEIQLNHANRQAAEALRNL 1647
Query: 212 QGASGCWK-------------DDLQKELSDIWSAVHVLQNSIDSL 243
+ G K DDL+++L+ + +++Q ++ L
Sbjct: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEEL 1692
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 42.7 bits (99), Expect = 4e-04
Identities = 44/196 (22%), Positives = 87/196 (44%), Gaps = 17/196 (8%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKES-CLQQIKIQQLEEVLSPTGRQGEKEEHKWG 93
E + +++++ T+ L+ ++ L KE LQ+ Q L+++ + + + K
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK 1032
Query: 94 MEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR 153
+EQ +L G+L Q EK LR E + + L+L + I D +
Sbjct: 1033 LEQQVDDLEGSLEQ-----EKKLRMDLERAKRKLEGDLKLAQESIMD-----------IE 1076
Query: 154 EEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQG 213
E + +KL+ +E EIS I+ Q ++ +K + +++ + E E E +
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 214 ASGCWKDDLQKELSDI 229
+ + DL +EL +I
Sbjct: 1137 KAEKQRSDLSRELEEI 1152
Score = 31.2 bits (69), Expect = 1.1
Identities = 50/228 (21%), Positives = 97/228 (42%), Gaps = 31/228 (13%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQ-GEKEEHKWG 93
E SL ++L A+E + L++E+ Q +I L E ++ G++ E E+ K
Sbjct: 1479 EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538
Query: 94 MEQGRQELYGALTQGLQGLE----KTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
+EQ + EL AL + LE K LR E+ + ++ ++ ++ EE+
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD---------EEI 1589
Query: 150 ELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMK-QQGHETAACPETE 208
+ ++ I + +Q+ D + + +++K K L +M+ Q H E
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK---KMEGDLNEMEIQLNHANRMAAEAL 1646
Query: 209 EIPQGASGCWKD-------------DLQKELSDIWSAVHVLQNSIDSL 243
+ G KD DL+++L+ + ++LQ I+ L
Sbjct: 1647 RNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1694
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 42.7 bits (99), Expect = 4e-04
Identities = 44/196 (22%), Positives = 87/196 (44%), Gaps = 17/196 (8%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKES-CLQQIKIQQLEEVLSPTGRQGEKEEHKWG 93
E + +++++ T+ L+ ++ L KE LQ+ Q L+++ + + + K
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK 1032
Query: 94 MEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVR 153
+EQ +L G+L Q EK LR E + + L+L + I D +
Sbjct: 1033 LEQQVDDLEGSLEQ-----EKKLRMDLERAKRKLEGDLKLAQESIMD-----------IE 1076
Query: 154 EEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQG 213
E + +KL+ +E EIS I+ Q ++ +K + +++ + E E E +
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 214 ASGCWKDDLQKELSDI 229
+ + DL +EL +I
Sbjct: 1137 KAEKQRSDLSRELEEI 1152
Score = 31.2 bits (69), Expect = 1.1
Identities = 50/228 (21%), Positives = 97/228 (42%), Gaps = 31/228 (13%)
Query: 35 ELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQ-GEKEEHKWG 93
E SL ++L A+E + L++E+ Q +I L E ++ G++ E E+ K
Sbjct: 1479 EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538
Query: 94 MEQGRQELYGALTQGLQGLE----KTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
+EQ + EL AL + LE K LR E+ + ++ ++ ++ EE+
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD---------EEI 1589
Query: 150 ELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVKCRKILTKMK-QQGHETAACPETE 208
+ ++ I + +Q+ D + + +++K K L +M+ Q H E
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK---KMEGDLNEMEIQLNHANRMAAEAL 1646
Query: 209 EIPQGASGCWKD-------------DLQKELSDIWSAVHVLQNSIDSL 243
+ G KD DL+++L+ + ++LQ I+ L
Sbjct: 1647 RNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1694
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 41.6 bits (96), Expect = 8e-04
Identities = 47/198 (23%), Positives = 91/198 (45%), Gaps = 32/198 (16%)
Query: 27 DSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGE 86
+ +K +R E E ++ Q + + E + E++ Q+ K+Q+ EE + E
Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQ----EEKMWEQEEKMQEQEE------KMWE 58
Query: 87 KEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLW 146
+EE W E+ E Q L ++ + + +E R + R +R+ K +W
Sbjct: 59 QEEKMWEQEEKMWE-----QQRLPEQKEKMWEQDERLREKEER--------MREQK--MW 103
Query: 147 EELELVREEVTFIYQKLQAQEDEISENLVNI----QKMQKTQVKCRKILTKMKQQGHETA 202
+++E +RE+ +K+Q QE+++ E + +KMQ+ + K + KM++Q +
Sbjct: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 163
Query: 203 ACPETEEIPQGASGCWKD 220
E EE QG +D
Sbjct: 164 ---EQEEKMQGQEEKMRD 178
Score = 37.7 bits (86), Expect = 0.012
Identities = 35/172 (20%), Positives = 88/172 (51%), Gaps = 16/172 (9%)
Query: 27 DSQKLLRCELESLKSQLQAQTKAFEFL-NHSVTMLEKESCL--QQIKIQQLEEVLSPTGR 83
+ ++++R + E ++ Q + + E + M E+E + Q+ K+ + EE + R
Sbjct: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75
Query: 84 QGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQE--IRDS 141
E++E W ++ +E + + +K + E+M+ + T+ ++ QE +++
Sbjct: 76 LPEQKEKMWEQDERLREKEERMRE-----QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 142 KKFLWEELELVREEVTFIY---QKLQAQEDEISENLVNIQKMQKTQVKCRKI 190
++ +WE+ E ++E+ ++ +K++ QE+++ E +KMQ + K R +
Sbjct: 131 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE---QEEKMQGQEEKMRDV 179
Score = 31.2 bits (69), Expect = 1.1
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 136 QEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNI----QKMQKTQVKCRKIL 191
+ +R+ +K + EE E++RE+ +K+Q QE+++ E + +KMQ+ + K +
Sbjct: 5 ERMREREKKMREEEEMMREQ----EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 192 TKMKQQGHETAACPETEEIPQGASGCWKDD 221
KM +Q + E + +P+ W+ D
Sbjct: 61 EKMWEQEEKMW---EQQRLPEQKEKMWEQD 87
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 41.6 bits (96), Expect = 8e-04
Identities = 47/187 (25%), Positives = 85/187 (45%), Gaps = 48/187 (25%)
Query: 3 EHEQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEK 62
+HE V ++ + K +K +V + EL+ L+SQL A
Sbjct: 266 KHEAVMNVKKQTQKGNSKKVVQMEQ-------ELQDLQSQLCA----------------- 301
Query: 63 ESCLQQIKIQQLEEVLSPTGRQGEKEEHKWGME--QGRQELYGALTQGLQGLEKTLRDSE 120
E QQ +++QLE+ E+E+H G+E QG ++L L Q LQ + E
Sbjct: 302 EQAQQQARVEQLEKTFQ------EEEQHLQGLEIAQGEKDLKQQLAQALQEHWALM---E 352
Query: 121 EMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKM 180
E+ R++ + I +K +ELE +EE +K+QAQ++E+ ++ ++ +
Sbjct: 353 ELNRSKKD------FEAIIQAKN---KELEQTKEE----KEKMQAQKEEVLSHMNDVLEN 399
Query: 181 QKTQVKC 187
+ + C
Sbjct: 400 ELQCIIC 406
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/251 (18%), Positives = 105/251 (41%), Gaps = 11/251 (4%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
++++ L ++ K++ + M + ++ ++ E+E + + ++ + L+KE+
Sbjct: 220 DEIQTLTEANEKIEVQNQEMRKNLEESVQ-EMEKMTDEYNRMKAIVHQTDNVIDQLKKEN 278
Query: 65 CLQQIKIQQLEEVLSPTGRQGEK---------EEHKWGMEQGRQELYGALTQGLQGLEKT 115
Q+++Q+L ++L + + EE K + E+ Q L L +
Sbjct: 279 DHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEII-EYQQMLHNLREK 337
Query: 116 LRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLV 175
L++++ LQ QE K L E++E +E+ ++ ++E+ N
Sbjct: 338 LKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKG 397
Query: 176 NIQKMQKTQVKCRKILTKMKQQGHETAACPETEEIPQGASGCWKDDLQKELSDIWSAVHV 235
Q+T +K + L +K++ E E E + K L D S V+
Sbjct: 398 ASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYG 457
Query: 236 LQNSIDSLTLC 246
L++++ + C
Sbjct: 458 LEDAVVEIKNC 468
Score = 31.6 bits (70), Expect = 0.88
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 15/142 (10%)
Query: 30 KLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKESCLQQIKIQQLEEVLSPTGRQGEKEE 89
K LR ++SL+ Q + S TM++ LQ K++ ++E+ + ++E
Sbjct: 1261 KHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQ----LQNDKLKIMQEM------KNSQQE 1310
Query: 90 HKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRARTTRCLQLLAQEIRDSKKFLWEEL 149
H+ ME E+ L +GL+ L TL+D++ Q+ + +E+R + L EL
Sbjct: 1311 HR-NMENKTLEMELKL-KGLEELISTLKDTKGAQKVINWH---MKIEELRLQELKLNREL 1365
Query: 150 ELVREEVTFIYQKLQAQEDEIS 171
+EE+ ++ + E IS
Sbjct: 1366 VKDKEEIKYLNNIISEYERTIS 1387
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 41.2 bits (95), Expect = 0.001
Identities = 50/206 (24%), Positives = 88/206 (42%), Gaps = 44/206 (21%)
Query: 35 ELESLKSQLQAQTKAFE------------------------FLNHSVTMLEKESCLQQ-- 68
ELE K +LQ + K + FL+ ++L++E ++Q
Sbjct: 2454 ELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEK 2513
Query: 69 IKIQQL--EEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRAR 126
K++QL +EV + E++ + MEQ RQ L ++ + + ++EE R R
Sbjct: 2514 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA----RRRQHEAEEGVR-R 2568
Query: 127 TTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK 186
LQ L Q+ R ++ L EE + +RE+ LQ E++ L + +++ +QV
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAALAHSEEVTASQVA 2621
Query: 187 CRKILTKMKQQGHETAACPETEEIPQ 212
TK G + P E P+
Sbjct: 2622 A----TKTLPNGRDALDGPAAEAEPE 2643
Score = 38.1 bits (87), Expect = 0.009
Identities = 36/182 (19%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
E+ + + + A++ + ++++L + E +++ QAQ A + + + +
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQR 124
+Q ++Q + E E+HK EQ TLR ++++
Sbjct: 2151 QAEQAALRQKQAA------DAEMEKHKKFAEQ------------------TLRQKAQVEQ 2186
Query: 125 ARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQ 184
TT LQL +E K L EEL+ ++ E T ++ E+E+ V ++++ K +
Sbjct: 2187 ELTTLRLQL--EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 185 VK 186
+
Sbjct: 2245 AR 2246
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 41.2 bits (95), Expect = 0.001
Identities = 50/206 (24%), Positives = 88/206 (42%), Gaps = 44/206 (21%)
Query: 35 ELESLKSQLQAQTKAFE------------------------FLNHSVTMLEKESCLQQ-- 68
ELE K +LQ + K + FL+ ++L++E ++Q
Sbjct: 2458 ELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEK 2517
Query: 69 IKIQQL--EEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRAR 126
K++QL +EV + E++ + MEQ RQ L ++ + + ++EE R R
Sbjct: 2518 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA----RRRQHEAEEGVR-R 2572
Query: 127 TTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK 186
LQ L Q+ R ++ L EE + +RE+ LQ E++ L + +++ +QV
Sbjct: 2573 KQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAALAHSEEVTASQVA 2625
Query: 187 CRKILTKMKQQGHETAACPETEEIPQ 212
TK G + P E P+
Sbjct: 2626 A----TKTLPNGRDALDGPAAEAEPE 2647
Score = 38.1 bits (87), Expect = 0.009
Identities = 36/182 (19%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
E+ + + + A++ + ++++L + E +++ QAQ A + + + +
Sbjct: 2095 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQR 124
+Q ++Q + E E+HK EQ TLR ++++
Sbjct: 2155 QAEQAALRQKQAA------DAEMEKHKKFAEQ------------------TLRQKAQVEQ 2190
Query: 125 ARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQ 184
TT LQL +E K L EEL+ ++ E T ++ E+E+ V ++++ K +
Sbjct: 2191 ELTTLRLQL--EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2248
Query: 185 VK 186
+
Sbjct: 2249 AR 2250
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 41.2 bits (95), Expect = 0.001
Identities = 50/206 (24%), Positives = 88/206 (42%), Gaps = 44/206 (21%)
Query: 35 ELESLKSQLQAQTKAFE------------------------FLNHSVTMLEKESCLQQ-- 68
ELE K +LQ + K + FL+ ++L++E ++Q
Sbjct: 2454 ELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEK 2513
Query: 69 IKIQQL--EEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQRAR 126
K++QL +EV + E++ + MEQ RQ L ++ + + ++EE R R
Sbjct: 2514 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA----RRRQHEAEEGVR-R 2568
Query: 127 TTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQVK 186
LQ L Q+ R ++ L EE + +RE+ LQ E++ L + +++ +QV
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAALAHSEEVTASQVA 2621
Query: 187 CRKILTKMKQQGHETAACPETEEIPQ 212
TK G + P E P+
Sbjct: 2622 A----TKTLPNGRDALDGPAAEAEPE 2643
Score = 38.1 bits (87), Expect = 0.009
Identities = 36/182 (19%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 5 EQVKPLETSSSKVKAKTIVMIPDSQKLLRCELESLKSQLQAQTKAFEFLNHSVTMLEKES 64
E+ + + + A++ + ++++L + E +++ QAQ A + + + +
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 65 CLQQIKIQQLEEVLSPTGRQGEKEEHKWGMEQGRQELYGALTQGLQGLEKTLRDSEEMQR 124
+Q ++Q + E E+HK EQ TLR ++++
Sbjct: 2151 QAEQAALRQKQAA------DAEMEKHKKFAEQ------------------TLRQKAQVEQ 2186
Query: 125 ARTTRCLQLLAQEIRDSKKFLWEELELVREEVTFIYQKLQAQEDEISENLVNIQKMQKTQ 184
TT LQL +E K L EEL+ ++ E T ++ E+E+ V ++++ K +
Sbjct: 2187 ELTTLRLQL--EETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 185 VK 186
+
Sbjct: 2245 AR 2246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,757,880
Number of Sequences: 37866
Number of extensions: 538287
Number of successful extensions: 2728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 2178
Number of HSP's gapped (non-prelim): 780
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.