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Search of human proteins with 209870075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209870075 caspase 5 isoform d [Homo sapiens]
(216 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209870079 caspase 5 isoform f precursor [Homo sapiens] 441 e-124
gi|209870075 caspase 5 isoform d [Homo sapiens] 441 e-124
gi|209870073 caspase 5 isoform c [Homo sapiens] 441 e-124
gi|209870071 caspase 5 isoform b precursor [Homo sapiens] 441 e-124
gi|209870069 caspase 5 isoform a precursor [Homo sapiens] 441 e-124
gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens] 368 e-102
gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens] 368 e-102
gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens] 261 2e-70
gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens] 261 2e-70
gi|4502573 caspase 1 isoform beta precursor [Homo sapiens] 261 2e-70
gi|15431332 caspase 1 isoform delta [Homo sapiens] 197 7e-51
gi|15431334 caspase 1 isoform epsilon [Homo sapiens] 93 2e-19
gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens] 89 4e-18
gi|14790115 caspase 3 preproprotein [Homo sapiens] 74 9e-14
gi|14790119 caspase 3 preproprotein [Homo sapiens] 74 9e-14
gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens] 66 3e-11
gi|6912286 caspase 14 precursor [Homo sapiens] 65 6e-11
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] 62 4e-10
gi|15718698 caspase 7 isoform delta [Homo sapiens] 61 6e-10
gi|15718700 caspase 7 isoform alpha [Homo sapiens] 61 6e-10
gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens] 61 6e-10
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] 60 1e-09
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] 60 1e-09
gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens] 55 3e-08
gi|14916485 caspase 6 isoform beta [Homo sapiens] 54 8e-08
gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [... 46 3e-05
gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [... 46 3e-05
gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 44 1e-04
gi|122056474 caspase 8 isoform C precursor [Homo sapiens] 44 1e-04
gi|15718708 caspase 8 isoform C precursor [Homo sapiens] 44 1e-04
>gi|209870079 caspase 5 isoform f precursor [Homo sapiens]
Length = 447
Score = 441 bits (1134), Expect = e-124
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH
Sbjct: 232 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 291
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ
Sbjct: 292 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 351
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME
Sbjct: 352 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 411
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 412 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 447
>gi|209870075 caspase 5 isoform d [Homo sapiens]
Length = 216
Score = 441 bits (1134), Expect = e-124
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH
Sbjct: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ
Sbjct: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME
Sbjct: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
>gi|209870073 caspase 5 isoform c [Homo sapiens]
Length = 292
Score = 441 bits (1134), Expect = e-124
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH
Sbjct: 77 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 136
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ
Sbjct: 137 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 196
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME
Sbjct: 197 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 256
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 257 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
>gi|209870071 caspase 5 isoform b precursor [Homo sapiens]
Length = 376
Score = 441 bits (1134), Expect = e-124
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH
Sbjct: 161 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 220
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ
Sbjct: 221 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 280
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME
Sbjct: 281 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 340
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 341 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 376
>gi|209870069 caspase 5 isoform a precursor [Homo sapiens]
Length = 434
Score = 441 bits (1134), Expect = e-124
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH
Sbjct: 219 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 278
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ
Sbjct: 279 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 338
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME
Sbjct: 339 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 398
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 399 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 434
>gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens]
Length = 321
Score = 368 bits (944), Expect = e-102
Identities = 180/216 (83%), Positives = 192/216 (88%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MK LL+GL Y+V E+NLTARDMES LRAFA RPEHKSSDSTFLVLMSHGILEGICGT H
Sbjct: 106 MKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVH 165
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
+KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG GELWVRDSPASL + SSQ
Sbjct: 166 DEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQ 225
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLE D+V K H EKDFIAFCSSTPHNVSWRD T GSIFIT+LITCFQKYS CCHL E
Sbjct: 226 SSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEE 285
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
+FRKVQ+SFE P+AKAQMPTIER ++TR FYLFPGN
Sbjct: 286 VFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 321
>gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]
Length = 377
Score = 368 bits (944), Expect = e-102
Identities = 180/216 (83%), Positives = 192/216 (88%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
MK LL+GL Y+V E+NLTARDMES LRAFA RPEHKSSDSTFLVLMSHGILEGICGT H
Sbjct: 162 MKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVH 221
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
+KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG GELWVRDSPASL + SSQ
Sbjct: 222 DEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQ 281
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
SSENLE D+V K H EKDFIAFCSSTPHNVSWRD T GSIFIT+LITCFQKYS CCHL E
Sbjct: 282 SSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEE 341
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
+FRKVQ+SFE P+AKAQMPTIER ++TR FYLFPGN
Sbjct: 342 VFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 377
>gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]
Length = 311
Score = 261 bits (668), Expect = 2e-70
Identities = 130/216 (60%), Positives = 156/216 (72%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H
Sbjct: 96 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 155
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ G +W +DS +S
Sbjct: 156 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP 215
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
++E E D++ K H EKDFIAFCSSTP NVSWR T GS+FI LI Q+Y+C C + E
Sbjct: 216 TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 275
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 276 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 311
>gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]
Length = 404
Score = 261 bits (668), Expect = 2e-70
Identities = 130/216 (60%), Positives = 156/216 (72%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H
Sbjct: 189 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 248
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ G +W +DS +S
Sbjct: 249 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP 308
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
++E E D++ K H EKDFIAFCSSTP NVSWR T GS+FI LI Q+Y+C C + E
Sbjct: 309 TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 368
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 369 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 404
>gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]
Length = 383
Score = 261 bits (668), Expect = 2e-70
Identities = 130/216 (60%), Positives = 156/216 (72%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H
Sbjct: 168 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 227
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ G +W +DS +S
Sbjct: 228 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP 287
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
++E E D++ K H EKDFIAFCSSTP NVSWR T GS+FI LI Q+Y+C C + E
Sbjct: 288 TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 347
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 348 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 383
>gi|15431332 caspase 1 isoform delta [Homo sapiens]
Length = 263
Score = 197 bits (500), Expect = 7e-51
Identities = 108/216 (50%), Positives = 127/216 (58%), Gaps = 48/216 (22%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H
Sbjct: 96 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 155
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
++ PD+L + IF + N +NC SLKDKPKVII+QACRG+
Sbjct: 156 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD-------------------- 195
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
NVSWR T GS+FI LI Q+Y+C C + E
Sbjct: 196 ----------------------------NVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 227
Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 228 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
>gi|15431334 caspase 1 isoform epsilon [Homo sapiens]
Length = 88
Score = 92.8 bits (229), Expect = 2e-19
Identities = 47/85 (55%), Positives = 57/85 (67%)
Query: 132 KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEV 191
K+ +EK + S NVSWR T GS+FI LI Q+Y+C C + EIFRKV+ SFE
Sbjct: 4 KVLKEKRKLFIRSMGEDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQ 63
Query: 192 PQAKAQMPTIERATLTRDFYLFPGN 216
P +AQMPT ER TLTR FYLFPG+
Sbjct: 64 PDGRAQMPTTERVTLTRCFYLFPGH 88
>gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]
Length = 452
Score = 88.6 bits (218), Expect = 4e-18
Identities = 65/223 (29%), Positives = 104/223 (46%), Gaps = 15/223 (6%)
Query: 4 LLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKK 63
L + LGY V + TA++M+ L+ FA P H+ +DS + L+SHG+ I G K
Sbjct: 232 LFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGK-- 289
Query: 64 KPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALI--SSQS 121
+L +FQ+F+N NC SL++KPK+ +QACRG++ + + A +S
Sbjct: 290 ---LLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEES 346
Query: 122 SENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEI 181
E ++ D I + + R+ RGS +I L F + +C H+ ++
Sbjct: 347 DAGKEKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADM 406
Query: 182 FRKVQKSFEVPQAKAQMPTIER--------ATLTRDFYLFPGN 216
KV + + A R +TL R YLFPG+
Sbjct: 407 LVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGH 449
>gi|14790115 caspase 3 preproprotein [Homo sapiens]
Length = 277
Score = 73.9 bits (180), Expect = 9e-14
Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 38/227 (16%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHG---ILEGICG 57
++ + L Y V ++ +LT ++ ++R ++ +H S VL+SHG I+ G G
Sbjct: 74 LRETFRNLKYEVRNKNDLTREEIVELMRD-VSKEDHSKRSSFVCVLLSHGEEGIIFGTNG 132
Query: 58 TAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALI 117
KK I F C SL KPK+ I+QACRG +
Sbjct: 133 PVDLKK---------ITNFFRGDRCRSLTGKPKLFIIQACRGTELD-------------C 170
Query: 118 SSQSSENLEADSVC-KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCC 176
++ ++ D C KI E DF+ S+ P SWR+ GS FI L ++Y+
Sbjct: 171 GIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL 230
Query: 177 HLMEIF----RKVQKSFE------VPQAKAQMPTIERATLTRDFYLF 213
M I RKV FE AK Q+P I + LT++ Y +
Sbjct: 231 EFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIV-SMLTKELYFY 276
>gi|14790119 caspase 3 preproprotein [Homo sapiens]
Length = 277
Score = 73.9 bits (180), Expect = 9e-14
Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 38/227 (16%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHG---ILEGICG 57
++ + L Y V ++ +LT ++ ++R ++ +H S VL+SHG I+ G G
Sbjct: 74 LRETFRNLKYEVRNKNDLTREEIVELMRD-VSKEDHSKRSSFVCVLLSHGEEGIIFGTNG 132
Query: 58 TAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALI 117
KK I F C SL KPK+ I+QACRG +
Sbjct: 133 PVDLKK---------ITNFFRGDRCRSLTGKPKLFIIQACRGTELD-------------C 170
Query: 118 SSQSSENLEADSVC-KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCC 176
++ ++ D C KI E DF+ S+ P SWR+ GS FI L ++Y+
Sbjct: 171 GIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL 230
Query: 177 HLMEIF----RKVQKSFE------VPQAKAQMPTIERATLTRDFYLF 213
M I RKV FE AK Q+P I + LT++ Y +
Sbjct: 231 EFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIV-SMLTKELYFY 276
>gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens]
Length = 416
Score = 65.9 bits (159), Expect = 3e-11
Identities = 57/218 (26%), Positives = 94/218 (43%), Gaps = 25/218 (11%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
++R L + V + +LTA+ M L A + +H + D +V++SHG C +H
Sbjct: 190 LRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQ-DHGALDCCVVVILSHG-----CQASH 243
Query: 61 KKKKPDV-------LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEK--HGELWVRDSP 111
+ V + + I IFN +C SL KPK+ +QAC GE+ HG SP
Sbjct: 244 LQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSP 303
Query: 112 ASLALISSQSSENL----------EADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIF 161
+ S+ + + D++ + D S+ P VSWRD GS +
Sbjct: 304 EDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWY 363
Query: 162 ITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMP 199
+ L F++++ L + +V + V QMP
Sbjct: 364 VETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMP 401
>gi|6912286 caspase 14 precursor [Homo sapiens]
Length = 242
Score = 64.7 bits (156), Expect = 6e-11
Identities = 57/219 (26%), Positives = 104/219 (47%), Gaps = 23/219 (10%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSS--DSTFLVLMSHGILEGICGT 58
++ + + L + +++ TA + L F + + F+VLM+HG EG
Sbjct: 39 LEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVLMAHG-REGFL-- 95
Query: 59 AHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALIS 118
K + +++ + +F+ NN+NC +L+ KPKV I+QACRGE+ RD + +
Sbjct: 96 --KGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQ------RDPGET---VG 144
Query: 119 SQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHL 178
+ DS I D + S+ +++R +GS FI L+ F K H+
Sbjct: 145 GDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRK--GHI 202
Query: 179 MEIF----RKVQKSFEVPQAKAQMPTIE-RATLTRDFYL 212
+E+ R++ ++ V + KA+ E ++TL + YL
Sbjct: 203 LELLTEVTRRMAEAELVQEGKARKTNPEIQSTLRKRLYL 241
>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
Length = 521
Score = 62.0 bits (149), Expect = 4e-10
Identities = 54/190 (28%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
+ + Q LG+TV N+T +ME VL+ P H D +++HG G +
Sbjct: 310 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF----GAVY 365
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
+ + + + I F C L +KPK+ +QAC+GE E+ S + AL Q
Sbjct: 366 SSDEALIPIRE-IMSHFTALQCPRLAEKPKLFFIQACQGE---EIQPSVSIEADALNPEQ 421
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
+ +L+ DS I E DF+ ++ P VS+R GS +I L C HL +
Sbjct: 422 APTSLQ-DS---IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSL---------CNHLKK 468
Query: 181 IFRKVQKSFE 190
+ ++ K E
Sbjct: 469 LVPRMLKFLE 478
>gi|15718698 caspase 7 isoform delta [Homo sapiens]
Length = 336
Score = 61.2 bits (147), Expect = 6e-10
Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 27/219 (12%)
Query: 3 RLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKK 62
+ + LG+ V+ + + M+ +L+ A+ +H ++ +L+SHG I G
Sbjct: 132 KCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACILLSHGEENVIYG----- 185
Query: 63 KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSS 122
K V + F C +L +KPK+ +QACRG + + DS
Sbjct: 186 -KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI--------- 235
Query: 123 ENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF 182
+ +A+ KI E DF+ S+ P SWR RGS F+ L + +++ +M+I
Sbjct: 236 NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQIL 295
Query: 183 RKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 211
+V + FE K Q+P + + LT++ Y
Sbjct: 296 TRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 333
>gi|15718700 caspase 7 isoform alpha [Homo sapiens]
Length = 303
Score = 61.2 bits (147), Expect = 6e-10
Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 27/219 (12%)
Query: 3 RLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKK 62
+ + LG+ V+ + + M+ +L+ A+ +H ++ +L+SHG I G
Sbjct: 99 KCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACILLSHGEENVIYG----- 152
Query: 63 KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSS 122
K V + F C +L +KPK+ +QACRG + + DS
Sbjct: 153 -KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI--------- 202
Query: 123 ENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF 182
+ +A+ KI E DF+ S+ P SWR RGS F+ L + +++ +M+I
Sbjct: 203 NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQIL 262
Query: 183 RKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 211
+V + FE K Q+P + + LT++ Y
Sbjct: 263 TRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 300
>gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens]
Length = 303
Score = 61.2 bits (147), Expect = 6e-10
Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 27/219 (12%)
Query: 3 RLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKK 62
+ + LG+ V+ + + M+ +L+ A+ +H ++ +L+SHG I G
Sbjct: 99 KCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACILLSHGEENVIYG----- 152
Query: 63 KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSS 122
K V + F C +L +KPK+ +QACRG + + DS
Sbjct: 153 -KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI--------- 202
Query: 123 ENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF 182
+ +A+ KI E DF+ S+ P SWR RGS F+ L + +++ +M+I
Sbjct: 203 NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQIL 262
Query: 183 RKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 211
+V + FE K Q+P + + LT++ Y
Sbjct: 263 TRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 300
>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
Length = 522
Score = 60.5 bits (145), Expect = 1e-09
Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 12/171 (7%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
+ + Q LG+TV N+T +ME VL+ P H D +++HG G +
Sbjct: 310 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF----GAVY 365
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
+ + + + I F C L +KPK+ +QAC+GE E+ S + AL Q
Sbjct: 366 SSDEALIPIRE-IMSHFTALQCPRLAEKPKLFFIQACQGE---EIQPSVSIEADALNPEQ 421
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQK 171
+ +L+ DS I E DF+ ++ P VS+R GS +I L +K
Sbjct: 422 APTSLQ-DS---IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKK 468
>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
Length = 479
Score = 60.5 bits (145), Expect = 1e-09
Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 12/171 (7%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
+ + Q LG+TV N+T +ME VL+ P H D +++HG G +
Sbjct: 267 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF----GAVY 322
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
+ + + + I F C L +KPK+ +QAC+GE E+ S + AL Q
Sbjct: 323 SSDEALIPIRE-IMSHFTALQCPRLAEKPKLFFIQACQGE---EIQPSVSIEADALNPEQ 378
Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQK 171
+ +L+ DS I E DF+ ++ P VS+R GS +I L +K
Sbjct: 379 APTSLQ-DS---IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKK 425
>gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens]
Length = 293
Score = 55.5 bits (132), Expect = 3e-08
Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 31/231 (13%)
Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
+ R LG+ V +L A ++ + + H +D V +SHG EG A+
Sbjct: 74 LTRRFSDLGFEVKCFNDLKAEELLLKIHEVST-VSHADADCFVCVFLSHG--EGNHIYAY 130
Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPA-SLALISS 119
K + T+ +F C SL KPK+ I+QACRG +H D P L ++ +
Sbjct: 131 DAK----IEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQH------DVPVIPLDVVDN 180
Query: 120 QSSE------NLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYS 173
Q+ + ++A SV + DF+ S S R+ GS +I +L KY
Sbjct: 181 QTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYG 240
Query: 174 CCCHLMEIFRKVQKSF--------EVPQA--KAQMPTIERATLTRDFYLFP 214
E+ V + + P A K Q+P + LT+ + FP
Sbjct: 241 SSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCF-ASMLTKKLHFFP 290
>gi|14916485 caspase 6 isoform beta [Homo sapiens]
Length = 204
Score = 54.3 bits (129), Expect = 8e-08
Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 30/196 (15%)
Query: 36 HKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQ 95
H +D V +SHG EG A+ K + T+ +F C SL KPK+ I+Q
Sbjct: 19 HADADCFVCVFLSHG--EGNHIYAYDAK----IEIQTLTGLFKGDKCHSLVGKPKIFIIQ 72
Query: 96 ACRGEKHGELWVRDSPA-SLALISSQSSE------NLEADSVCKIHEEKDFIAFCSSTPH 148
ACRG +H D P L ++ +Q+ + ++A SV + DF+ S
Sbjct: 73 ACRGNQH------DVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEG 126
Query: 149 NVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSF--------EVPQA--KAQM 198
S R+ GS +I +L KY E+ V + + P A K Q+
Sbjct: 127 YYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQV 186
Query: 199 PTIERATLTRDFYLFP 214
P + LT+ + FP
Sbjct: 187 PCF-ASMLTKKLHFFP 201
>gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1
[Homo sapiens]
Length = 480
Score = 45.8 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 12/136 (8%)
Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67
LGY V +L+ + +L FA PEH+ DS VL+S G + + G +
Sbjct: 274 LGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGV---DQTHSG 330
Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127
L I ++F +C L KPK+ +Q G+L +SL + + +N+E
Sbjct: 331 LPLHHIRRMFMGDSCPYLAGKPKMFFIQN-YVVSEGQL----EDSSLLEVDGPAMKNVEF 385
Query: 128 DS----VCKIHEEKDF 139
+ +C +H E DF
Sbjct: 386 KAQKRGLCTVHREADF 401
>gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1
[Homo sapiens]
Length = 480
Score = 45.8 bits (107), Expect = 3e-05
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 12/136 (8%)
Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67
LGY V +L+ + +L FA PEH+ DS VL+S G + + G +
Sbjct: 274 LGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGV---DQTHSG 330
Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127
L I ++F +C L KPK+ +Q G+L +SL + + +N+E
Sbjct: 331 LPLHHIRRMFMGDSCPYLAGKPKMFFIQN-YVVSEGQL----EDSSLLEVDGPAMKNVEF 385
Query: 128 DS----VCKIHEEKDF 139
+ +C +H E DF
Sbjct: 386 KAQKRGLCTVHREADF 401
>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
Length = 538
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 17/162 (10%)
Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67
L + + + T + +L+ + +H + D ++SHG I GT ++
Sbjct: 336 LHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP--- 391
Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127
+Y+ Q F C SL KPKV +QAC+G+ + + P S+ LE
Sbjct: 392 -IYELTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEM 442
Query: 128 D----SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 165
D I +E DF+ ++ + VS+R+ G+ +I L
Sbjct: 443 DLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 484
>gi|122056474 caspase 8 isoform C precursor [Homo sapiens]
Length = 464
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 17/162 (10%)
Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67
L + + + T + +L+ + +H + D ++SHG I GT ++
Sbjct: 262 LHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP--- 317
Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127
+Y+ Q F C SL KPKV +QAC+G+ + + P S+ LE
Sbjct: 318 -IYELTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEM 368
Query: 128 D----SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 165
D I +E DF+ ++ + VS+R+ G+ +I L
Sbjct: 369 DLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 410
>gi|15718708 caspase 8 isoform C precursor [Homo sapiens]
Length = 464
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 17/162 (10%)
Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67
L + + + T + +L+ + +H + D ++SHG I GT ++
Sbjct: 262 LHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP--- 317
Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127
+Y+ Q F C SL KPKV +QAC+G+ + + P S+ LE
Sbjct: 318 -IYELTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEM 368
Query: 128 D----SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 165
D I +E DF+ ++ + VS+R+ G+ +I L
Sbjct: 369 DLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,916,125
Number of Sequences: 37866
Number of extensions: 308858
Number of successful extensions: 667
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 605
Number of HSP's gapped (non-prelim): 46
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.