BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|209870075 caspase 5 isoform d [Homo sapiens] (216 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|209870079 caspase 5 isoform f precursor [Homo sapiens] 441 e-124 gi|209870075 caspase 5 isoform d [Homo sapiens] 441 e-124 gi|209870073 caspase 5 isoform c [Homo sapiens] 441 e-124 gi|209870071 caspase 5 isoform b precursor [Homo sapiens] 441 e-124 gi|209870069 caspase 5 isoform a precursor [Homo sapiens] 441 e-124 gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens] 368 e-102 gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens] 368 e-102 gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens] 261 2e-70 gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens] 261 2e-70 gi|4502573 caspase 1 isoform beta precursor [Homo sapiens] 261 2e-70 gi|15431332 caspase 1 isoform delta [Homo sapiens] 197 7e-51 gi|15431334 caspase 1 isoform epsilon [Homo sapiens] 93 2e-19 gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens] 89 4e-18 gi|14790115 caspase 3 preproprotein [Homo sapiens] 74 9e-14 gi|14790119 caspase 3 preproprotein [Homo sapiens] 74 9e-14 gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens] 66 3e-11 gi|6912286 caspase 14 precursor [Homo sapiens] 65 6e-11 gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] 62 4e-10 gi|15718698 caspase 7 isoform delta [Homo sapiens] 61 6e-10 gi|15718700 caspase 7 isoform alpha [Homo sapiens] 61 6e-10 gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens] 61 6e-10 gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] 60 1e-09 gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] 60 1e-09 gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens] 55 3e-08 gi|14916485 caspase 6 isoform beta [Homo sapiens] 54 8e-08 gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [... 46 3e-05 gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [... 46 3e-05 gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 44 1e-04 gi|122056474 caspase 8 isoform C precursor [Homo sapiens] 44 1e-04 gi|15718708 caspase 8 isoform C precursor [Homo sapiens] 44 1e-04 >gi|209870079 caspase 5 isoform f precursor [Homo sapiens] Length = 447 Score = 441 bits (1134), Expect = e-124 Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH Sbjct: 232 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 291 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ Sbjct: 292 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 351 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME Sbjct: 352 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 411 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN Sbjct: 412 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 447 >gi|209870075 caspase 5 isoform d [Homo sapiens] Length = 216 Score = 441 bits (1134), Expect = e-124 Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH Sbjct: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ Sbjct: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME Sbjct: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN Sbjct: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 >gi|209870073 caspase 5 isoform c [Homo sapiens] Length = 292 Score = 441 bits (1134), Expect = e-124 Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH Sbjct: 77 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 136 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ Sbjct: 137 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 196 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME Sbjct: 197 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 256 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN Sbjct: 257 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292 >gi|209870071 caspase 5 isoform b precursor [Homo sapiens] Length = 376 Score = 441 bits (1134), Expect = e-124 Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH Sbjct: 161 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 220 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ Sbjct: 221 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 280 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME Sbjct: 281 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 340 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN Sbjct: 341 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 376 >gi|209870069 caspase 5 isoform a precursor [Homo sapiens] Length = 434 Score = 441 bits (1134), Expect = e-124 Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH Sbjct: 219 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 278 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ Sbjct: 279 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 338 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME Sbjct: 339 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 398 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN Sbjct: 399 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 434 >gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens] Length = 321 Score = 368 bits (944), Expect = e-102 Identities = 180/216 (83%), Positives = 192/216 (88%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MK LL+GL Y+V E+NLTARDMES LRAFA RPEHKSSDSTFLVLMSHGILEGICGT H Sbjct: 106 MKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVH 165 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 +KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG GELWVRDSPASL + SSQ Sbjct: 166 DEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQ 225 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLE D+V K H EKDFIAFCSSTPHNVSWRD T GSIFIT+LITCFQKYS CCHL E Sbjct: 226 SSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEE 285 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 +FRKVQ+SFE P+AKAQMPTIER ++TR FYLFPGN Sbjct: 286 VFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 321 >gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens] Length = 377 Score = 368 bits (944), Expect = e-102 Identities = 180/216 (83%), Positives = 192/216 (88%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 MK LL+GL Y+V E+NLTARDMES LRAFA RPEHKSSDSTFLVLMSHGILEGICGT H Sbjct: 162 MKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVH 221 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 +KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG GELWVRDSPASL + SSQ Sbjct: 222 DEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQ 281 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 SSENLE D+V K H EKDFIAFCSSTPHNVSWRD T GSIFIT+LITCFQKYS CCHL E Sbjct: 282 SSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEE 341 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 +FRKVQ+SFE P+AKAQMPTIER ++TR FYLFPGN Sbjct: 342 VFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 377 >gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens] Length = 311 Score = 261 bits (668), Expect = 2e-70 Identities = 130/216 (60%), Positives = 156/216 (72%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H Sbjct: 96 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 155 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ G +W +DS +S Sbjct: 156 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP 215 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 ++E E D++ K H EKDFIAFCSSTP NVSWR T GS+FI LI Q+Y+C C + E Sbjct: 216 TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 275 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+ Sbjct: 276 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 311 >gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens] Length = 404 Score = 261 bits (668), Expect = 2e-70 Identities = 130/216 (60%), Positives = 156/216 (72%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H Sbjct: 189 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 248 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ G +W +DS +S Sbjct: 249 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP 308 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 ++E E D++ K H EKDFIAFCSSTP NVSWR T GS+FI LI Q+Y+C C + E Sbjct: 309 TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 368 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+ Sbjct: 369 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 404 >gi|4502573 caspase 1 isoform beta precursor [Homo sapiens] Length = 383 Score = 261 bits (668), Expect = 2e-70 Identities = 130/216 (60%), Positives = 156/216 (72%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H Sbjct: 168 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 227 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ G +W +DS +S Sbjct: 228 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP 287 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 ++E E D++ K H EKDFIAFCSSTP NVSWR T GS+FI LI Q+Y+C C + E Sbjct: 288 TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 347 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+ Sbjct: 348 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 383 >gi|15431332 caspase 1 isoform delta [Homo sapiens] Length = 263 Score = 197 bits (500), Expect = 7e-51 Identities = 108/216 (50%), Positives = 127/216 (58%), Gaps = 48/216 (22%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H Sbjct: 96 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 155 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+ Sbjct: 156 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD-------------------- 195 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 NVSWR T GS+FI LI Q+Y+C C + E Sbjct: 196 ----------------------------NVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 227 Query: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216 IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+ Sbjct: 228 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263 >gi|15431334 caspase 1 isoform epsilon [Homo sapiens] Length = 88 Score = 92.8 bits (229), Expect = 2e-19 Identities = 47/85 (55%), Positives = 57/85 (67%) Query: 132 KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEV 191 K+ +EK + S NVSWR T GS+FI LI Q+Y+C C + EIFRKV+ SFE Sbjct: 4 KVLKEKRKLFIRSMGEDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQ 63 Query: 192 PQAKAQMPTIERATLTRDFYLFPGN 216 P +AQMPT ER TLTR FYLFPG+ Sbjct: 64 PDGRAQMPTTERVTLTRCFYLFPGH 88 >gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens] Length = 452 Score = 88.6 bits (218), Expect = 4e-18 Identities = 65/223 (29%), Positives = 104/223 (46%), Gaps = 15/223 (6%) Query: 4 LLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKK 63 L + LGY V + TA++M+ L+ FA P H+ +DS + L+SHG+ I G K Sbjct: 232 LFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGK-- 289 Query: 64 KPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALI--SSQS 121 +L +FQ+F+N NC SL++KPK+ +QACRG++ + + A +S Sbjct: 290 ---LLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEES 346 Query: 122 SENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEI 181 E ++ D I + + R+ RGS +I L F + +C H+ ++ Sbjct: 347 DAGKEKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADM 406 Query: 182 FRKVQKSFEVPQAKAQMPTIER--------ATLTRDFYLFPGN 216 KV + + A R +TL R YLFPG+ Sbjct: 407 LVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGH 449 >gi|14790115 caspase 3 preproprotein [Homo sapiens] Length = 277 Score = 73.9 bits (180), Expect = 9e-14 Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 38/227 (16%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHG---ILEGICG 57 ++ + L Y V ++ +LT ++ ++R ++ +H S VL+SHG I+ G G Sbjct: 74 LRETFRNLKYEVRNKNDLTREEIVELMRD-VSKEDHSKRSSFVCVLLSHGEEGIIFGTNG 132 Query: 58 TAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALI 117 KK I F C SL KPK+ I+QACRG + Sbjct: 133 PVDLKK---------ITNFFRGDRCRSLTGKPKLFIIQACRGTELD-------------C 170 Query: 118 SSQSSENLEADSVC-KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCC 176 ++ ++ D C KI E DF+ S+ P SWR+ GS FI L ++Y+ Sbjct: 171 GIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL 230 Query: 177 HLMEIF----RKVQKSFE------VPQAKAQMPTIERATLTRDFYLF 213 M I RKV FE AK Q+P I + LT++ Y + Sbjct: 231 EFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIV-SMLTKELYFY 276 >gi|14790119 caspase 3 preproprotein [Homo sapiens] Length = 277 Score = 73.9 bits (180), Expect = 9e-14 Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 38/227 (16%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHG---ILEGICG 57 ++ + L Y V ++ +LT ++ ++R ++ +H S VL+SHG I+ G G Sbjct: 74 LRETFRNLKYEVRNKNDLTREEIVELMRD-VSKEDHSKRSSFVCVLLSHGEEGIIFGTNG 132 Query: 58 TAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALI 117 KK I F C SL KPK+ I+QACRG + Sbjct: 133 PVDLKK---------ITNFFRGDRCRSLTGKPKLFIIQACRGTELD-------------C 170 Query: 118 SSQSSENLEADSVC-KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCC 176 ++ ++ D C KI E DF+ S+ P SWR+ GS FI L ++Y+ Sbjct: 171 GIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL 230 Query: 177 HLMEIF----RKVQKSFE------VPQAKAQMPTIERATLTRDFYLF 213 M I RKV FE AK Q+P I + LT++ Y + Sbjct: 231 EFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIV-SMLTKELYFY 276 >gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens] Length = 416 Score = 65.9 bits (159), Expect = 3e-11 Identities = 57/218 (26%), Positives = 94/218 (43%), Gaps = 25/218 (11%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 ++R L + V + +LTA+ M L A + +H + D +V++SHG C +H Sbjct: 190 LRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQ-DHGALDCCVVVILSHG-----CQASH 243 Query: 61 KKKKPDV-------LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEK--HGELWVRDSP 111 + V + + I IFN +C SL KPK+ +QAC GE+ HG SP Sbjct: 244 LQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSP 303 Query: 112 ASLALISSQSSENL----------EADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIF 161 + S+ + + D++ + D S+ P VSWRD GS + Sbjct: 304 EDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWY 363 Query: 162 ITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMP 199 + L F++++ L + +V + V QMP Sbjct: 364 VETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMP 401 >gi|6912286 caspase 14 precursor [Homo sapiens] Length = 242 Score = 64.7 bits (156), Expect = 6e-11 Identities = 57/219 (26%), Positives = 104/219 (47%), Gaps = 23/219 (10%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSS--DSTFLVLMSHGILEGICGT 58 ++ + + L + +++ TA + L F + + F+VLM+HG EG Sbjct: 39 LEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVLMAHG-REGFL-- 95 Query: 59 AHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALIS 118 K + +++ + +F+ NN+NC +L+ KPKV I+QACRGE+ RD + + Sbjct: 96 --KGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQ------RDPGET---VG 144 Query: 119 SQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHL 178 + DS I D + S+ +++R +GS FI L+ F K H+ Sbjct: 145 GDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRK--GHI 202 Query: 179 MEIF----RKVQKSFEVPQAKAQMPTIE-RATLTRDFYL 212 +E+ R++ ++ V + KA+ E ++TL + YL Sbjct: 203 LELLTEVTRRMAEAELVQEGKARKTNPEIQSTLRKRLYL 241 >gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] Length = 521 Score = 62.0 bits (149), Expect = 4e-10 Identities = 54/190 (28%), Positives = 86/190 (45%), Gaps = 21/190 (11%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 + + Q LG+TV N+T +ME VL+ P H D +++HG G + Sbjct: 310 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF----GAVY 365 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 + + + + I F C L +KPK+ +QAC+GE E+ S + AL Q Sbjct: 366 SSDEALIPIRE-IMSHFTALQCPRLAEKPKLFFIQACQGE---EIQPSVSIEADALNPEQ 421 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180 + +L+ DS I E DF+ ++ P VS+R GS +I L C HL + Sbjct: 422 APTSLQ-DS---IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSL---------CNHLKK 468 Query: 181 IFRKVQKSFE 190 + ++ K E Sbjct: 469 LVPRMLKFLE 478 >gi|15718698 caspase 7 isoform delta [Homo sapiens] Length = 336 Score = 61.2 bits (147), Expect = 6e-10 Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 27/219 (12%) Query: 3 RLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKK 62 + + LG+ V+ + + M+ +L+ A+ +H ++ +L+SHG I G Sbjct: 132 KCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACILLSHGEENVIYG----- 185 Query: 63 KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSS 122 K V + F C +L +KPK+ +QACRG + + DS Sbjct: 186 -KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI--------- 235 Query: 123 ENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF 182 + +A+ KI E DF+ S+ P SWR RGS F+ L + +++ +M+I Sbjct: 236 NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQIL 295 Query: 183 RKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 211 +V + FE K Q+P + + LT++ Y Sbjct: 296 TRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 333 >gi|15718700 caspase 7 isoform alpha [Homo sapiens] Length = 303 Score = 61.2 bits (147), Expect = 6e-10 Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 27/219 (12%) Query: 3 RLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKK 62 + + LG+ V+ + + M+ +L+ A+ +H ++ +L+SHG I G Sbjct: 99 KCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACILLSHGEENVIYG----- 152 Query: 63 KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSS 122 K V + F C +L +KPK+ +QACRG + + DS Sbjct: 153 -KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI--------- 202 Query: 123 ENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF 182 + +A+ KI E DF+ S+ P SWR RGS F+ L + +++ +M+I Sbjct: 203 NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQIL 262 Query: 183 RKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 211 +V + FE K Q+P + + LT++ Y Sbjct: 263 TRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 300 >gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens] Length = 303 Score = 61.2 bits (147), Expect = 6e-10 Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 27/219 (12%) Query: 3 RLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKK 62 + + LG+ V+ + + M+ +L+ A+ +H ++ +L+SHG I G Sbjct: 99 KCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACILLSHGEENVIYG----- 152 Query: 63 KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSS 122 K V + F C +L +KPK+ +QACRG + + DS Sbjct: 153 -KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI--------- 202 Query: 123 ENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF 182 + +A+ KI E DF+ S+ P SWR RGS F+ L + +++ +M+I Sbjct: 203 NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQIL 262 Query: 183 RKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 211 +V + FE K Q+P + + LT++ Y Sbjct: 263 TRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 300 >gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] Length = 522 Score = 60.5 bits (145), Expect = 1e-09 Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 12/171 (7%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 + + Q LG+TV N+T +ME VL+ P H D +++HG G + Sbjct: 310 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF----GAVY 365 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 + + + + I F C L +KPK+ +QAC+GE E+ S + AL Q Sbjct: 366 SSDEALIPIRE-IMSHFTALQCPRLAEKPKLFFIQACQGE---EIQPSVSIEADALNPEQ 421 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQK 171 + +L+ DS I E DF+ ++ P VS+R GS +I L +K Sbjct: 422 APTSLQ-DS---IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKK 468 >gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] Length = 479 Score = 60.5 bits (145), Expect = 1e-09 Identities = 50/171 (29%), Positives = 79/171 (46%), Gaps = 12/171 (7%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 + + Q LG+TV N+T +ME VL+ P H D +++HG G + Sbjct: 267 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF----GAVY 322 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120 + + + + I F C L +KPK+ +QAC+GE E+ S + AL Q Sbjct: 323 SSDEALIPIRE-IMSHFTALQCPRLAEKPKLFFIQACQGE---EIQPSVSIEADALNPEQ 378 Query: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQK 171 + +L+ DS I E DF+ ++ P VS+R GS +I L +K Sbjct: 379 APTSLQ-DS---IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKK 425 >gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens] Length = 293 Score = 55.5 bits (132), Expect = 3e-08 Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 31/231 (13%) Query: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60 + R LG+ V +L A ++ + + H +D V +SHG EG A+ Sbjct: 74 LTRRFSDLGFEVKCFNDLKAEELLLKIHEVST-VSHADADCFVCVFLSHG--EGNHIYAY 130 Query: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPA-SLALISS 119 K + T+ +F C SL KPK+ I+QACRG +H D P L ++ + Sbjct: 131 DAK----IEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQH------DVPVIPLDVVDN 180 Query: 120 QSSE------NLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYS 173 Q+ + ++A SV + DF+ S S R+ GS +I +L KY Sbjct: 181 QTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYG 240 Query: 174 CCCHLMEIFRKVQKSF--------EVPQA--KAQMPTIERATLTRDFYLFP 214 E+ V + + P A K Q+P + LT+ + FP Sbjct: 241 SSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCF-ASMLTKKLHFFP 290 >gi|14916485 caspase 6 isoform beta [Homo sapiens] Length = 204 Score = 54.3 bits (129), Expect = 8e-08 Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 30/196 (15%) Query: 36 HKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQ 95 H +D V +SHG EG A+ K + T+ +F C SL KPK+ I+Q Sbjct: 19 HADADCFVCVFLSHG--EGNHIYAYDAK----IEIQTLTGLFKGDKCHSLVGKPKIFIIQ 72 Query: 96 ACRGEKHGELWVRDSPA-SLALISSQSSE------NLEADSVCKIHEEKDFIAFCSSTPH 148 ACRG +H D P L ++ +Q+ + ++A SV + DF+ S Sbjct: 73 ACRGNQH------DVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEG 126 Query: 149 NVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSF--------EVPQA--KAQM 198 S R+ GS +I +L KY E+ V + + P A K Q+ Sbjct: 127 YYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQV 186 Query: 199 PTIERATLTRDFYLFP 214 P + LT+ + FP Sbjct: 187 PCF-ASMLTKKLHFFP 201 >gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [Homo sapiens] Length = 480 Score = 45.8 bits (107), Expect = 3e-05 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 12/136 (8%) Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67 LGY V +L+ + +L FA PEH+ DS VL+S G + + G + Sbjct: 274 LGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGV---DQTHSG 330 Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127 L I ++F +C L KPK+ +Q G+L +SL + + +N+E Sbjct: 331 LPLHHIRRMFMGDSCPYLAGKPKMFFIQN-YVVSEGQL----EDSSLLEVDGPAMKNVEF 385 Query: 128 DS----VCKIHEEKDF 139 + +C +H E DF Sbjct: 386 KAQKRGLCTVHREADF 401 >gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [Homo sapiens] Length = 480 Score = 45.8 bits (107), Expect = 3e-05 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 12/136 (8%) Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67 LGY V +L+ + +L FA PEH+ DS VL+S G + + G + Sbjct: 274 LGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGV---DQTHSG 330 Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127 L I ++F +C L KPK+ +Q G+L +SL + + +N+E Sbjct: 331 LPLHHIRRMFMGDSCPYLAGKPKMFFIQN-YVVSEGQL----EDSSLLEVDGPAMKNVEF 385 Query: 128 DS----VCKIHEEKDF 139 + +C +H E DF Sbjct: 386 KAQKRGLCTVHREADF 401 >gi|122056476 caspase 8 isoform G precursor [Homo sapiens] Length = 538 Score = 43.9 bits (102), Expect = 1e-04 Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 17/162 (10%) Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67 L + + + T + +L+ + +H + D ++SHG I GT ++ Sbjct: 336 LHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP--- 391 Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127 +Y+ Q F C SL KPKV +QAC+G+ + + P S+ LE Sbjct: 392 -IYELTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEM 442 Query: 128 D----SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 165 D I +E DF+ ++ + VS+R+ G+ +I L Sbjct: 443 DLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 484 >gi|122056474 caspase 8 isoform C precursor [Homo sapiens] Length = 464 Score = 43.9 bits (102), Expect = 1e-04 Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 17/162 (10%) Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67 L + + + T + +L+ + +H + D ++SHG I GT ++ Sbjct: 262 LHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP--- 317 Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127 +Y+ Q F C SL KPKV +QAC+G+ + + P S+ LE Sbjct: 318 -IYELTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEM 368 Query: 128 D----SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 165 D I +E DF+ ++ + VS+R+ G+ +I L Sbjct: 369 DLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 410 >gi|15718708 caspase 8 isoform C precursor [Homo sapiens] Length = 464 Score = 43.9 bits (102), Expect = 1e-04 Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 17/162 (10%) Query: 8 LGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV 67 L + + + T + +L+ + +H + D ++SHG I GT ++ Sbjct: 262 LHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP--- 317 Query: 68 LLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEA 127 +Y+ Q F C SL KPKV +QAC+G+ + + P S+ LE Sbjct: 318 -IYELTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEM 368 Query: 128 D----SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 165 D I +E DF+ ++ + VS+R+ G+ +I L Sbjct: 369 DLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 410 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.135 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,916,125 Number of Sequences: 37866 Number of extensions: 308858 Number of successful extensions: 667 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 605 Number of HSP's gapped (non-prelim): 46 length of query: 216 length of database: 18,247,518 effective HSP length: 98 effective length of query: 118 effective length of database: 14,536,650 effective search space: 1715324700 effective search space used: 1715324700 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.