Search of human proteins with 209870073

Search of human proteins with 209870073

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209870073 caspase 5 isoform c [Homo sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209870073 caspase 5 isoform c [Homo sapiens]                       596   e-171
gi|209870079 caspase 5 isoform f precursor [Homo sapiens]             591   e-169
gi|209870071 caspase 5 isoform b precursor [Homo sapiens]             591   e-169
gi|209870069 caspase 5 isoform a precursor [Homo sapiens]             591   e-169
gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens]          477   e-135
gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]           477   e-135
gi|209870075 caspase 5 isoform d [Homo sapiens]                       441   e-124
gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]          323   1e-88
gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]          323   1e-88
gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]            323   1e-88
gi|15431332 caspase 1 isoform delta [Homo sapiens]                    258   4e-69
gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]           98   1e-20
gi|15431334 caspase 1 isoform epsilon [Homo sapiens]                   93   3e-19
gi|14790115 caspase 3 preproprotein [Homo sapiens]                     83   3e-16
gi|14790119 caspase 3 preproprotein [Homo sapiens]                     83   3e-16
gi|6912286 caspase 14 precursor [Homo sapiens]                         81   1e-15
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]          77   2e-14
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]          75   5e-14
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]          75   5e-14
gi|15718698 caspase 7 isoform delta [Homo sapiens]                     75   9e-14
gi|15718700 caspase 7 isoform alpha [Homo sapiens]                     75   9e-14
gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens]            75   9e-14
gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens]       74   2e-13
gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens]       65   9e-11
gi|122056476 caspase 8 isoform G precursor [Homo sapiens]              56   3e-08
gi|122056474 caspase 8 isoform C precursor [Homo sapiens]              56   3e-08
gi|15718708 caspase 8 isoform C precursor [Homo sapiens]               56   3e-08
gi|15718706 caspase 8 isoform B precursor [Homo sapiens]               56   3e-08
gi|15718704 caspase 8 isoform A precursor [Homo sapiens]               56   3e-08
gi|14916485 caspase 6 isoform beta [Homo sapiens]                      54   1e-07

>gi|209870073 caspase 5 isoform c [Homo sapiens]
          Length = 292

 Score =  596 bits (1536), Expect = e-171
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MAALLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTK 60
           MAALLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTK
Sbjct: 1   MAALLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTK 60

Query: 61  FDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFL 120
           FDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFL
Sbjct: 61  FDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFL 120

Query: 121 VLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE 180
           VLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE
Sbjct: 121 VLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE 180

Query: 181 LWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITE 240
           LWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITE
Sbjct: 181 LWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITE 240

Query: 241 LITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           LITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 241 LITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292


>gi|209870079 caspase 5 isoform f precursor [Homo sapiens]
          Length = 447

 Score =  591 bits (1523), Expect = e-169
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 4   LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH 63
           LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH
Sbjct: 159 LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH 218

Query: 64  LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM 123
           LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM
Sbjct: 219 LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM 278

Query: 124 SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV 183
           SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV
Sbjct: 279 SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV 338

Query: 184 RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT 243
           RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT
Sbjct: 339 RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT 398

Query: 244 CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 399 CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 447


>gi|209870071 caspase 5 isoform b precursor [Homo sapiens]
          Length = 376

 Score =  591 bits (1523), Expect = e-169
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 4   LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH 63
           LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH
Sbjct: 88  LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH 147

Query: 64  LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM 123
           LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM
Sbjct: 148 LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM 207

Query: 124 SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV 183
           SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV
Sbjct: 208 SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV 267

Query: 184 RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT 243
           RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT
Sbjct: 268 RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT 327

Query: 244 CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 328 CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 376


>gi|209870069 caspase 5 isoform a precursor [Homo sapiens]
          Length = 434

 Score =  591 bits (1523), Expect = e-169
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 4   LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH 63
           LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH
Sbjct: 146 LLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDH 205

Query: 64  LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM 123
           LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM
Sbjct: 206 LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLM 265

Query: 124 SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV 183
           SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV
Sbjct: 266 SHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWV 325

Query: 184 RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT 243
           RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT
Sbjct: 326 RDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELIT 385

Query: 244 CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 386 CFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 434


>gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens]
          Length = 321

 Score =  477 bits (1228), Expect = e-135
 Identities = 232/286 (81%), Positives = 252/286 (88%)

Query: 7   IEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPA 66
           +EAGPPES EST+ LKLCP EEFLRLCK+  +EIYPIK+R +R RLALIICNT+FDHLP 
Sbjct: 36  MEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPP 95

Query: 67  RNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHG 126
           RNGA +DI GMK LL+GL Y+V  E+NLTARDMES LRAFA RPEHKSSDSTFLVLMSHG
Sbjct: 96  RNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHG 155

Query: 127 ILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDS 186
           ILEGICGT H +KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG   GELWVRDS
Sbjct: 156 ILEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDS 215

Query: 187 PASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQ 246
           PASL + SSQSSENLE D+V K H EKDFIAFCSSTPHNVSWRD T GSIFIT+LITCFQ
Sbjct: 216 PASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQ 275

Query: 247 KYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           KYS CCHL E+FRKVQ+SFE P+AKAQMPTIER ++TR FYLFPGN
Sbjct: 276 KYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 321


>gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]
          Length = 377

 Score =  477 bits (1228), Expect = e-135
 Identities = 232/286 (81%), Positives = 252/286 (88%)

Query: 7   IEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPA 66
           +EAGPPES EST+ LKLCP EEFLRLCK+  +EIYPIK+R +R RLALIICNT+FDHLP 
Sbjct: 92  MEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPP 151

Query: 67  RNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHG 126
           RNGA +DI GMK LL+GL Y+V  E+NLTARDMES LRAFA RPEHKSSDSTFLVLMSHG
Sbjct: 152 RNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHG 211

Query: 127 ILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDS 186
           ILEGICGT H +KKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRG   GELWVRDS
Sbjct: 212 ILEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDS 271

Query: 187 PASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQ 246
           PASL + SSQSSENLE D+V K H EKDFIAFCSSTPHNVSWRD T GSIFIT+LITCFQ
Sbjct: 272 PASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQ 331

Query: 247 KYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           KYS CCHL E+FRKVQ+SFE P+AKAQMPTIER ++TR FYLFPGN
Sbjct: 332 KYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 377


>gi|209870075 caspase 5 isoform d [Homo sapiens]
          Length = 216

 Score =  441 bits (1134), Expect = e-124
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 77  MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 136
           MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH
Sbjct: 1   MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60

Query: 137 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 196
           KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ
Sbjct: 61  KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120

Query: 197 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 256
           SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME
Sbjct: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180

Query: 257 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
Sbjct: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216


>gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]
          Length = 311

 Score =  323 bits (827), Expect = 1e-88
 Identities = 163/281 (58%), Positives = 196/281 (69%)

Query: 12  PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 71
           P S+ S   +KLC  EE  R+ K+   EIYPI  +  R RLALIICN +FD +P R GA 
Sbjct: 31  PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90

Query: 72  YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 131
            DI GM  LLQ LGY+V  +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 91  VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150

Query: 132 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 191
           CG  H ++ PD+L  + IF + N +NC SLKDKPKVII+QACRG+  G +W +DS     
Sbjct: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSG 210

Query: 192 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 251
            +S  ++E  E D++ K H EKDFIAFCSSTP NVSWR  T GS+FI  LI   Q+Y+C 
Sbjct: 211 NLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACS 270

Query: 252 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           C + EIFRKV+ SFE P  +AQMPT ER TLTR FYLFPG+
Sbjct: 271 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 311


>gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]
          Length = 404

 Score =  323 bits (827), Expect = 1e-88
 Identities = 163/281 (58%), Positives = 196/281 (69%)

Query: 12  PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 71
           P S+ S   +KLC  EE  R+ K+   EIYPI  +  R RLALIICN +FD +P R GA 
Sbjct: 124 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 183

Query: 72  YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 131
            DI GM  LLQ LGY+V  +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 184 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 243

Query: 132 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 191
           CG  H ++ PD+L  + IF + N +NC SLKDKPKVII+QACRG+  G +W +DS     
Sbjct: 244 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSG 303

Query: 192 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 251
            +S  ++E  E D++ K H EKDFIAFCSSTP NVSWR  T GS+FI  LI   Q+Y+C 
Sbjct: 304 NLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACS 363

Query: 252 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           C + EIFRKV+ SFE P  +AQMPT ER TLTR FYLFPG+
Sbjct: 364 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 404


>gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]
          Length = 383

 Score =  323 bits (827), Expect = 1e-88
 Identities = 163/281 (58%), Positives = 196/281 (69%)

Query: 12  PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 71
           P S+ S   +KLC  EE  R+ K+   EIYPI  +  R RLALIICN +FD +P R GA 
Sbjct: 103 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 162

Query: 72  YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 131
            DI GM  LLQ LGY+V  +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 163 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 222

Query: 132 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 191
           CG  H ++ PD+L  + IF + N +NC SLKDKPKVII+QACRG+  G +W +DS     
Sbjct: 223 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSG 282

Query: 192 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 251
            +S  ++E  E D++ K H EKDFIAFCSSTP NVSWR  T GS+FI  LI   Q+Y+C 
Sbjct: 283 NLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACS 342

Query: 252 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           C + EIFRKV+ SFE P  +AQMPT ER TLTR FYLFPG+
Sbjct: 343 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 383


>gi|15431332 caspase 1 isoform delta [Homo sapiens]
          Length = 263

 Score =  258 bits (659), Expect = 4e-69
 Identities = 141/281 (50%), Positives = 167/281 (59%), Gaps = 48/281 (17%)

Query: 12  PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 71
           P S+ S   +KLC  EE  R+ K+   EIYPI  +  R RLALIICN +FD +P R GA 
Sbjct: 31  PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90

Query: 72  YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 131
            DI GM  LLQ LGY+V  +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 91  VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150

Query: 132 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 191
           CG  H ++ PD+L  + IF + N +NC SLKDKPKVII+QACRG+               
Sbjct: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD--------------- 195

Query: 192 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 251
                                            NVSWR  T GS+FI  LI   Q+Y+C 
Sbjct: 196 ---------------------------------NVSWRHPTMGSVFIGRLIEHMQEYACS 222

Query: 252 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
           C + EIFRKV+ SFE P  +AQMPT ER TLTR FYLFPG+
Sbjct: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263


>gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]
          Length = 452

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 75/256 (29%), Positives = 118/256 (46%), Gaps = 18/256 (7%)

Query: 50  RRLALIICNTKFD---HLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAF 106
           R LAL++ N  F     L  R+G   D   +  L + LGY V    + TA++M+  L+ F
Sbjct: 199 RGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNF 258

Query: 107 AARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPK 166
           A  P H+ +DS  + L+SHG+   I G   K     +L    +FQ+F+N NC SL++KPK
Sbjct: 259 AQLPAHRVTDSCIVALLSHGVEGAIYGVDGK-----LLQLQEVFQLFDNANCPSLQNKPK 313

Query: 167 VIIVQACRGEKHGELWVRDSPASLALI--SSQSSENLEADSVCKIHEEKDFIAFCSSTPH 224
           +  +QACRG++      +    + A      +S    E     ++    D I   +    
Sbjct: 314 MFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACLKG 373

Query: 225 NVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIER----- 279
             + R+  RGS +I  L   F + +C  H+ ++  KV    +  +  A      R     
Sbjct: 374 TAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGYAPGTEFHRCKEMS 433

Query: 280 ---ATLTRDFYLFPGN 292
              +TL R  YLFPG+
Sbjct: 434 EYCSTLCRHLYLFPGH 449


>gi|15431334 caspase 1 isoform epsilon [Homo sapiens]
          Length = 88

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 47/85 (55%), Positives = 57/85 (67%)

Query: 208 KIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEV 267
           K+ +EK  +   S    NVSWR  T GS+FI  LI   Q+Y+C C + EIFRKV+ SFE 
Sbjct: 4   KVLKEKRKLFIRSMGEDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQ 63

Query: 268 PQAKAQMPTIERATLTRDFYLFPGN 292
           P  +AQMPT ER TLTR FYLFPG+
Sbjct: 64  PDGRAQMPTTERVTLTRCFYLFPGH 88


>gi|14790115 caspase 3 preproprotein [Homo sapiens]
          Length = 277

 Score = 82.8 bits (203), Expect = 3e-16
 Identities = 73/255 (28%), Positives = 110/255 (43%), Gaps = 41/255 (16%)

Query: 52  LALIICNTKFDH---LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAA 108
           L +II N  F     + +R+G   D   ++   + L Y V ++ +LT  ++  ++R   +
Sbjct: 46  LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRD-VS 104

Query: 109 RPEHKSSDSTFLVLMSHG---ILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 165
           + +H    S   VL+SHG   I+ G  G    KK         I   F    C SL  KP
Sbjct: 105 KEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKK---------ITNFFRGDRCRSLTGKP 155

Query: 166 KVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVC-KIHEEKDFIAFCSSTPH 224
           K+ I+QACRG +                  ++   ++ D  C KI  E DF+   S+ P 
Sbjct: 156 KLFIIQACRGTELD-------------CGIETDSGVDDDMACHKIPVEADFLYAYSTAPG 202

Query: 225 NVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF----RKVQKSFE------VPQAKAQM 274
             SWR+   GS FI  L    ++Y+     M I     RKV   FE         AK Q+
Sbjct: 203 YYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQI 262

Query: 275 PTIERATLTRDFYLF 289
           P I  + LT++ Y +
Sbjct: 263 PCIV-SMLTKELYFY 276


>gi|14790119 caspase 3 preproprotein [Homo sapiens]
          Length = 277

 Score = 82.8 bits (203), Expect = 3e-16
 Identities = 73/255 (28%), Positives = 110/255 (43%), Gaps = 41/255 (16%)

Query: 52  LALIICNTKFDH---LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAA 108
           L +II N  F     + +R+G   D   ++   + L Y V ++ +LT  ++  ++R   +
Sbjct: 46  LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRD-VS 104

Query: 109 RPEHKSSDSTFLVLMSHG---ILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 165
           + +H    S   VL+SHG   I+ G  G    KK         I   F    C SL  KP
Sbjct: 105 KEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKK---------ITNFFRGDRCRSLTGKP 155

Query: 166 KVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVC-KIHEEKDFIAFCSSTPH 224
           K+ I+QACRG +                  ++   ++ D  C KI  E DF+   S+ P 
Sbjct: 156 KLFIIQACRGTELD-------------CGIETDSGVDDDMACHKIPVEADFLYAYSTAPG 202

Query: 225 NVSWRDRTRGSIFITELITCFQKYSCCCHLMEIF----RKVQKSFE------VPQAKAQM 274
             SWR+   GS FI  L    ++Y+     M I     RKV   FE         AK Q+
Sbjct: 203 YYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQI 262

Query: 275 PTIERATLTRDFYLF 289
           P I  + LT++ Y +
Sbjct: 263 PCIV-SMLTKELYFY 276


>gi|6912286 caspase 14 precursor [Homo sapiens]
          Length = 242

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 69/245 (28%), Positives = 119/245 (48%), Gaps = 28/245 (11%)

Query: 51  RLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARP 110
           RLALI+C TK     AR G+  D+  ++ + + L +    +++ TA   +  L  F    
Sbjct: 18  RLALILCVTK-----AREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAI 72

Query: 111 EHKSS--DSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVI 168
           + +       F+VLM+HG  EG      K +  +++  + +F+  NN+NC +L+ KPKV 
Sbjct: 73  DSREDPVSCAFVVLMAHG-REGFL----KGEDGEMVKLENLFEALNNKNCQALRAKPKVY 127

Query: 169 IVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSW 228
           I+QACRGE+      RD   +   +       +  DS   I    D +   S+    +++
Sbjct: 128 IIQACRGEQ------RDPGET---VGGDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAY 178

Query: 229 RDRTRGSIFITELITCFQKYSCCCHLMEIF----RKVQKSFEVPQAKAQMPTIE-RATLT 283
           R   +GS FI  L+  F K     H++E+     R++ ++  V + KA+    E ++TL 
Sbjct: 179 RHDQKGSCFIQTLVDVFTKRK--GHILELLTEVTRRMAEAELVQEGKARKTNPEIQSTLR 236

Query: 284 RDFYL 288
           +  YL
Sbjct: 237 KRLYL 241


>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
          Length = 521

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 64/223 (28%), Positives = 100/223 (44%), Gaps = 21/223 (9%)

Query: 44  KKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVL 103
           +   + R L +I+ N  F  L  R G H D   +  + Q LG+TV    N+T  +ME VL
Sbjct: 277 RMNRNHRGLCVIVNNHSFTSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVL 336

Query: 104 RAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKD 163
           +     P H   D     +++HG      G  +   +  + + + I   F    C  L +
Sbjct: 337 QKQKCNPAHADGDCFVFCILTHGRF----GAVYSSDEALIPIRE-IMSHFTALQCPRLAE 391

Query: 164 KPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTP 223
           KPK+  +QAC+GE   E+    S  + AL   Q+  +L+ DS   I  E DF+   ++ P
Sbjct: 392 KPKLFFIQACQGE---EIQPSVSIEADALNPEQAPTSLQ-DS---IPAEADFLLGLATVP 444

Query: 224 HNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFE 266
             VS+R    GS +I  L         C HL ++  ++ K  E
Sbjct: 445 GYVSFRHVEEGSWYIQSL---------CNHLKKLVPRMLKFLE 478


>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
          Length = 522

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 60/204 (29%), Positives = 93/204 (45%), Gaps = 12/204 (5%)

Query: 44  KKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVL 103
           +   + R L +I+ N  F  L  R G H D   +  + Q LG+TV    N+T  +ME VL
Sbjct: 277 RMNRNHRGLCVIVNNHSFTSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVL 336

Query: 104 RAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKD 163
           +     P H   D     +++HG      G  +   +  + + + I   F    C  L +
Sbjct: 337 QKQKCNPAHADGDCFVFCILTHGRF----GAVYSSDEALIPIRE-IMSHFTALQCPRLAE 391

Query: 164 KPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTP 223
           KPK+  +QAC+GE   E+    S  + AL   Q+  +L+ DS   I  E DF+   ++ P
Sbjct: 392 KPKLFFIQACQGE---EIQPSVSIEADALNPEQAPTSLQ-DS---IPAEADFLLGLATVP 444

Query: 224 HNVSWRDRTRGSIFITELITCFQK 247
             VS+R    GS +I  L    +K
Sbjct: 445 GYVSFRHVEEGSWYIQSLCNHLKK 468


>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
          Length = 479

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 60/204 (29%), Positives = 93/204 (45%), Gaps = 12/204 (5%)

Query: 44  KKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVL 103
           +   + R L +I+ N  F  L  R G H D   +  + Q LG+TV    N+T  +ME VL
Sbjct: 234 RMNRNHRGLCVIVNNHSFTSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVL 293

Query: 104 RAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKD 163
           +     P H   D     +++HG      G  +   +  + + + I   F    C  L +
Sbjct: 294 QKQKCNPAHADGDCFVFCILTHGRF----GAVYSSDEALIPIRE-IMSHFTALQCPRLAE 348

Query: 164 KPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTP 223
           KPK+  +QAC+GE   E+    S  + AL   Q+  +L+ DS   I  E DF+   ++ P
Sbjct: 349 KPKLFFIQACQGE---EIQPSVSIEADALNPEQAPTSLQ-DS---IPAEADFLLGLATVP 401

Query: 224 HNVSWRDRTRGSIFITELITCFQK 247
             VS+R    GS +I  L    +K
Sbjct: 402 GYVSFRHVEEGSWYIQSLCNHLKK 425


>gi|15718698 caspase 7 isoform delta [Homo sapiens]
          Length = 336

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 71/296 (23%), Positives = 125/296 (42%), Gaps = 32/296 (10%)

Query: 7   IEAGPPESAESTNILKLCPREEFLRLCKKNHDEI--YPIKKREDRRRLALIICNTKFDHL 64
           ++A P  S+   ++     +   +R  K   D +  Y      ++    +II N  FD +
Sbjct: 55  VDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKV 114

Query: 65  PA---RNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLV 121
                RNG   D   + +  + LG+ V+   + +   M+ +L+  A+  +H ++     +
Sbjct: 115 TGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACI 173

Query: 122 LMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGEL 181
           L+SHG    I G      K  V     +   F    C +L +KPK+  +QACRG +  + 
Sbjct: 174 LLSHGEENVIYG------KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDG 227

Query: 182 WVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
              DS             + +A+   KI  E DF+   S+ P   SWR   RGS F+  L
Sbjct: 228 IQADSGPI---------NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQAL 278

Query: 242 ITCFQKYSCCCHLMEIFRKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 287
            +  +++     +M+I  +V     + FE          K Q+P +  + LT++ Y
Sbjct: 279 CSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 333


>gi|15718700 caspase 7 isoform alpha [Homo sapiens]
          Length = 303

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 71/296 (23%), Positives = 125/296 (42%), Gaps = 32/296 (10%)

Query: 7   IEAGPPESAESTNILKLCPREEFLRLCKKNHDEI--YPIKKREDRRRLALIICNTKFDHL 64
           ++A P  S+   ++     +   +R  K   D +  Y      ++    +II N  FD +
Sbjct: 22  VDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKV 81

Query: 65  PA---RNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLV 121
                RNG   D   + +  + LG+ V+   + +   M+ +L+  A+  +H ++     +
Sbjct: 82  TGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACI 140

Query: 122 LMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGEL 181
           L+SHG    I G      K  V     +   F    C +L +KPK+  +QACRG +  + 
Sbjct: 141 LLSHGEENVIYG------KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDG 194

Query: 182 WVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
              DS             + +A+   KI  E DF+   S+ P   SWR   RGS F+  L
Sbjct: 195 IQADSGPI---------NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQAL 245

Query: 242 ITCFQKYSCCCHLMEIFRKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 287
            +  +++     +M+I  +V     + FE          K Q+P +  + LT++ Y
Sbjct: 246 CSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 300


>gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens]
          Length = 303

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 71/296 (23%), Positives = 125/296 (42%), Gaps = 32/296 (10%)

Query: 7   IEAGPPESAESTNILKLCPREEFLRLCKKNHDEI--YPIKKREDRRRLALIICNTKFDHL 64
           ++A P  S+   ++     +   +R  K   D +  Y      ++    +II N  FD +
Sbjct: 22  VDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKV 81

Query: 65  PA---RNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLV 121
                RNG   D   + +  + LG+ V+   + +   M+ +L+  A+  +H ++     +
Sbjct: 82  TGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEEDHTNAACFACI 140

Query: 122 LMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGEL 181
           L+SHG    I G      K  V     +   F    C +L +KPK+  +QACRG +  + 
Sbjct: 141 LLSHGEENVIYG------KDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDG 194

Query: 182 WVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
              DS             + +A+   KI  E DF+   S+ P   SWR   RGS F+  L
Sbjct: 195 IQADSGPI---------NDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQAL 245

Query: 242 ITCFQKYSCCCHLMEIFRKVQ----KSFEVP------QAKAQMPTIERATLTRDFY 287
            +  +++     +M+I  +V     + FE          K Q+P +  + LT++ Y
Sbjct: 246 CSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVV-SMLTKELY 300


>gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens]
          Length = 416

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 66/244 (27%), Positives = 105/244 (43%), Gaps = 28/244 (11%)

Query: 54  LIICNTKF---DHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARP 110
           LII N  F     L  R G++ D   ++R    L + V  + +LTA+ M   L   A + 
Sbjct: 164 LIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQ- 222

Query: 111 EHKSSDSTFLVLMSHGILEGICGTAHKKKKPDV-------LLYDTIFQIFNNRNCLSLKD 163
           +H + D   +V++SHG     C  +H +    V       +  + I  IFN  +C SL  
Sbjct: 223 DHGALDCCVVVILSHG-----CQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGG 277

Query: 164 KPKVIIVQACRGEK--HGELWVRDSPASLALISSQSSENL----------EADSVCKIHE 211
           KPK+  +QAC GE+  HG      SP   +  S+   +            + D++  +  
Sbjct: 278 KPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPT 337

Query: 212 EKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAK 271
             D     S+ P  VSWRD   GS ++  L   F++++    L  +  +V  +  V    
Sbjct: 338 PSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIY 397

Query: 272 AQMP 275
            QMP
Sbjct: 398 KQMP 401


>gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens]
          Length = 293

 Score = 64.7 bits (156), Expect = 9e-11
 Identities = 71/262 (27%), Positives = 109/262 (41%), Gaps = 34/262 (12%)

Query: 49  RRRLALIICNTKFDH---LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRA 105
           RR +ALI  + +F     LP R G   D   + R    LG+ V    +L A ++   +  
Sbjct: 43  RRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHE 102

Query: 106 FAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKP 165
            +    H  +D    V +SHG  EG    A+  K    +   T+  +F    C SL  KP
Sbjct: 103 VST-VSHADADCFVCVFLSHG--EGNHIYAYDAK----IEIQTLTGLFKGDKCHSLVGKP 155

Query: 166 KVIIVQACRGEKHGELWVRDSPA-SLALISSQSSE------NLEADSVCKIHEEKDFIAF 218
           K+ I+QACRG +H      D P   L ++ +Q+ +       ++A SV  +    DF+  
Sbjct: 156 KIFIIQACRGNQH------DVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMC 209

Query: 219 CSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSF--------EVPQA 270
            S      S R+   GS +I +L     KY       E+   V +          + P A
Sbjct: 210 YSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSA 269

Query: 271 --KAQMPTIERATLTRDFYLFP 290
             K Q+P    + LT+  + FP
Sbjct: 270 IGKKQVPCF-ASMLTKKLHFFP 290


>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
          Length = 538

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 29/218 (13%)

Query: 38  DEIYPIKKREDRRRLALIICNTKF----DHLPA------RNGAHYDIVGMKRLLQGLGYT 87
           D++Y +K +   R   LII N  F    + +P       RNG H D   +    + L + 
Sbjct: 282 DKVYQMKSKP--RGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE 339

Query: 88  VVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYD 147
           +    + T   +  +L+ +    +H + D     ++SHG    I GT  ++      +Y+
Sbjct: 340 IKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP----IYE 394

Query: 148 TIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEAD--- 204
              Q F    C SL  KPKV  +QAC+G+     + +  P       S+    LE D   
Sbjct: 395 LTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEMDLSS 446

Query: 205 -SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
                I +E DF+   ++  + VS+R+   G+ +I  L
Sbjct: 447 PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 484


>gi|122056474 caspase 8 isoform C precursor [Homo sapiens]
          Length = 464

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 29/218 (13%)

Query: 38  DEIYPIKKREDRRRLALIICNTKF----DHLPA------RNGAHYDIVGMKRLLQGLGYT 87
           D++Y +K +   R   LII N  F    + +P       RNG H D   +    + L + 
Sbjct: 208 DKVYQMKSKP--RGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE 265

Query: 88  VVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYD 147
           +    + T   +  +L+ +    +H + D     ++SHG    I GT  ++      +Y+
Sbjct: 266 IKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP----IYE 320

Query: 148 TIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEAD--- 204
              Q F    C SL  KPKV  +QAC+G+     + +  P       S+    LE D   
Sbjct: 321 LTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEMDLSS 372

Query: 205 -SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
                I +E DF+   ++  + VS+R+   G+ +I  L
Sbjct: 373 PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 410


>gi|15718708 caspase 8 isoform C precursor [Homo sapiens]
          Length = 464

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 29/218 (13%)

Query: 38  DEIYPIKKREDRRRLALIICNTKF----DHLPA------RNGAHYDIVGMKRLLQGLGYT 87
           D++Y +K +   R   LII N  F    + +P       RNG H D   +    + L + 
Sbjct: 208 DKVYQMKSKP--RGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE 265

Query: 88  VVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYD 147
           +    + T   +  +L+ +    +H + D     ++SHG    I GT  ++      +Y+
Sbjct: 266 IKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP----IYE 320

Query: 148 TIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEAD--- 204
              Q F    C SL  KPKV  +QAC+G+     + +  P       S+    LE D   
Sbjct: 321 LTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEMDLSS 372

Query: 205 -SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
                I +E DF+   ++  + VS+R+   G+ +I  L
Sbjct: 373 PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 410


>gi|15718706 caspase 8 isoform B precursor [Homo sapiens]
          Length = 479

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 29/218 (13%)

Query: 38  DEIYPIKKREDRRRLALIICNTKF----DHLPA------RNGAHYDIVGMKRLLQGLGYT 87
           D++Y +K +   R   LII N  F    + +P       RNG H D   +    + L + 
Sbjct: 223 DKVYQMKSKP--RGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE 280

Query: 88  VVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYD 147
           +    + T   +  +L+ +    +H + D     ++SHG    I GT  ++      +Y+
Sbjct: 281 IKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP----IYE 335

Query: 148 TIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEAD--- 204
              Q F    C SL  KPKV  +QAC+G+     + +  P       S+    LE D   
Sbjct: 336 LTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEMDLSS 387

Query: 205 -SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
                I +E DF+   ++  + VS+R+   G+ +I  L
Sbjct: 388 PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 425


>gi|15718704 caspase 8 isoform A precursor [Homo sapiens]
          Length = 496

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 29/218 (13%)

Query: 38  DEIYPIKKREDRRRLALIICNTKF----DHLPA------RNGAHYDIVGMKRLLQGLGYT 87
           D++Y +K +   R   LII N  F    + +P       RNG H D   +    + L + 
Sbjct: 240 DKVYQMKSKP--RGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE 297

Query: 88  VVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYD 147
           +    + T   +  +L+ +    +H + D     ++SHG    I GT  ++      +Y+
Sbjct: 298 IKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEAP----IYE 352

Query: 148 TIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEAD--- 204
              Q F    C SL  KPKV  +QAC+G+     + +  P       S+    LE D   
Sbjct: 353 LTSQ-FTGLKCPSLAGKPKVFFIQACQGDN----YQKGIPVE---TDSEEQPYLEMDLSS 404

Query: 205 -SVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITEL 241
                I +E DF+   ++  + VS+R+   G+ +I  L
Sbjct: 405 PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL 442


>gi|14916485 caspase 6 isoform beta [Homo sapiens]
          Length = 204

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 30/196 (15%)

Query: 112 HKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQ 171
           H  +D    V +SHG  EG    A+  K    +   T+  +F    C SL  KPK+ I+Q
Sbjct: 19  HADADCFVCVFLSHG--EGNHIYAYDAK----IEIQTLTGLFKGDKCHSLVGKPKIFIIQ 72

Query: 172 ACRGEKHGELWVRDSPA-SLALISSQSSE------NLEADSVCKIHEEKDFIAFCSSTPH 224
           ACRG +H      D P   L ++ +Q+ +       ++A SV  +    DF+   S    
Sbjct: 73  ACRGNQH------DVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEG 126

Query: 225 NVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSF--------EVPQA--KAQM 274
             S R+   GS +I +L     KY       E+   V +          + P A  K Q+
Sbjct: 127 YYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQV 186

Query: 275 PTIERATLTRDFYLFP 290
           P    + LT+  + FP
Sbjct: 187 PCF-ASMLTKKLHFFP 201


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,162,648
Number of Sequences: 37866
Number of extensions: 449567
Number of successful extensions: 949
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 868
Number of HSP's gapped (non-prelim): 54
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.