BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|209862971 MAP-kinase activating death domain-containing protein isoform a [Homo sapiens] (1588 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|209862971 MAP-kinase activating death domain-containing prote... 3166 0.0 gi|209571517 MAP-kinase activating death domain-containing prote... 3160 0.0 gi|209862983 MAP-kinase activating death domain-containing prote... 3154 0.0 gi|209862994 MAP-kinase activating death domain-containing prote... 3127 0.0 gi|209862979 MAP-kinase activating death domain-containing prote... 3053 0.0 gi|209862998 MAP-kinase activating death domain-containing prote... 3046 0.0 gi|209862975 MAP-kinase activating death domain-containing prote... 3041 0.0 gi|209863002 MAP-kinase activating death domain-containing prote... 3040 0.0 gi|18860873 MAP-kinase activating death domain-containing protei... 2980 0.0 gi|209862987 MAP-kinase activating death domain-containing prote... 2905 0.0 gi|239735519 SET binding factor 1 [Homo sapiens] 103 1e-21 gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi... 90 2e-17 gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi... 90 2e-17 gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 84 1e-15 gi|94818781 DENN/MADD domain containing 4C [Homo sapiens] 77 1e-13 gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 77 1e-13 gi|29788755 SET binding factor 2 [Homo sapiens] 77 2e-13 gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 72 3e-12 gi|50345870 DENN/MADD domain containing 3 [Homo sapiens] 72 3e-12 gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 62 6e-09 gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 62 6e-09 gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo sapi... 62 6e-09 gi|121949817 DENN/MADD domain containing 2C [Homo sapiens] 59 5e-08 gi|154813195 DENN/MADD domain containing 2A [Homo sapiens] 58 6e-08 gi|113205087 DENN/MADD domain containing 1C [Homo sapiens] 58 6e-08 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 56 2e-07 gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo sapi... 56 3e-07 gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo sapi... 52 3e-06 gi|21361991 DENN/MADD domain containing 2D [Homo sapiens] 51 8e-06 gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens] 49 4e-05 >gi|209862971 MAP-kinase activating death domain-containing protein isoform a [Homo sapiens] Length = 1588 Score = 3166 bits (8208), Expect = 0.0 Identities = 1588/1588 (100%), Positives = 1588/1588 (100%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH Sbjct: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 Query: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL Sbjct: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 Query: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL Sbjct: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 Query: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG Sbjct: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 Query: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS Sbjct: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 Query: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL Sbjct: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 Query: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD Sbjct: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 Query: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI Sbjct: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 Query: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK Sbjct: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 Query: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR Sbjct: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 Query: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL Sbjct: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 Query: 1501 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1560 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY Sbjct: 1501 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1560 Query: 1561 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 SVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1561 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 >gi|209571517 MAP-kinase activating death domain-containing protein isoform h [Homo sapiens] Length = 1587 Score = 3160 bits (8192), Expect = 0.0 Identities = 1587/1588 (99%), Positives = 1587/1588 (99%), Gaps = 1/1588 (0%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH Sbjct: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 Query: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL Sbjct: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 Query: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL Sbjct: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 Query: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG Sbjct: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 Query: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS Sbjct: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 Query: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 VIGVSPAVMIRSSSQDSEVST VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL Sbjct: 1141 VIGVSPAVMIRSSSQDSEVST-VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1199 Query: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD Sbjct: 1200 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1259 Query: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI Sbjct: 1260 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1319 Query: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK Sbjct: 1320 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1379 Query: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR Sbjct: 1380 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1439 Query: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL Sbjct: 1440 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1499 Query: 1501 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1560 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY Sbjct: 1500 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1559 Query: 1561 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 SVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1560 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1587 >gi|209862983 MAP-kinase activating death domain-containing protein isoform e [Homo sapiens] Length = 1608 Score = 3154 bits (8177), Expect = 0.0 Identities = 1588/1608 (98%), Positives = 1588/1608 (98%), Gaps = 20/1608 (1%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK---------------- 884 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK Sbjct: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP 900 Query: 885 ----GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 940 GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW Sbjct: 901 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 960 Query: 941 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1000 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL Sbjct: 961 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1020 Query: 1001 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1060 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP Sbjct: 1021 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1080 Query: 1061 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQ 1120 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQ Sbjct: 1081 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQ 1140 Query: 1121 ISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSN 1180 ISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSN Sbjct: 1141 ISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSN 1200 Query: 1181 AGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDV 1240 AGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDV Sbjct: 1201 AGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDV 1260 Query: 1241 SQRVYLYEGLLGKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHD 1300 SQRVYLYEGLLGKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHD Sbjct: 1261 SQRVYLYEGLLGKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHD 1320 Query: 1301 RKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQ 1360 RKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQ Sbjct: 1321 RKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQ 1380 Query: 1361 LANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWW 1420 LANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWW Sbjct: 1381 LANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWW 1440 Query: 1421 YEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPG 1480 YEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPG Sbjct: 1441 YEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPG 1500 Query: 1481 PELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVP 1540 PELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVP Sbjct: 1501 PELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVP 1560 Query: 1541 EIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 EIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1561 EIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS 1608 >gi|209862994 MAP-kinase activating death domain-containing protein isoform d [Homo sapiens] Length = 1647 Score = 3127 bits (8108), Expect = 0.0 Identities = 1587/1647 (96%), Positives = 1587/1647 (96%), Gaps = 59/1647 (3%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK---------------- 884 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK Sbjct: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP 900 Query: 885 ----GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 940 GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW Sbjct: 901 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 960 Query: 941 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1000 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL Sbjct: 961 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1020 Query: 1001 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1060 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP Sbjct: 1021 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1080 Query: 1061 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASI------------------GP 1102 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASI P Sbjct: 1081 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP 1140 Query: 1103 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV 1162 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV Sbjct: 1141 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV 1200 Query: 1163 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK 1222 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK Sbjct: 1201 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK 1260 Query: 1223 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLG---------------------KERSTLWDQ 1261 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLG KERSTLWDQ Sbjct: 1261 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ 1320 Query: 1262 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS 1321 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS Sbjct: 1321 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS 1380 Query: 1322 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK 1381 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK Sbjct: 1381 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK 1440 Query: 1382 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR 1441 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR Sbjct: 1441 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR 1500 Query: 1442 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ 1501 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ Sbjct: 1501 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ 1560 Query: 1502 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS 1561 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS Sbjct: 1561 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS 1620 Query: 1562 VLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 VLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1621 VLCLFSYVAAVHSSEEDLRTPPRPVSS 1647 >gi|209862979 MAP-kinase activating death domain-containing protein isoform c [Homo sapiens] Length = 1545 Score = 3053 bits (7914), Expect = 0.0 Identities = 1545/1588 (97%), Positives = 1545/1588 (97%), Gaps = 43/1588 (2%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG------------------- 761 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 762 ------------------------AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 797 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH Sbjct: 798 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 857 Query: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL Sbjct: 858 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 917 Query: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL Sbjct: 918 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 977 Query: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG Sbjct: 978 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1037 Query: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS Sbjct: 1038 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1097 Query: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL Sbjct: 1098 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1157 Query: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD Sbjct: 1158 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1217 Query: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI Sbjct: 1218 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1277 Query: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK Sbjct: 1278 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1337 Query: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR Sbjct: 1338 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1397 Query: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL Sbjct: 1398 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1457 Query: 1501 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1560 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY Sbjct: 1458 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1517 Query: 1561 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 SVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1518 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1545 >gi|209862998 MAP-kinase activating death domain-containing protein isoform i [Homo sapiens] Length = 1544 Score = 3046 bits (7898), Expect = 0.0 Identities = 1544/1588 (97%), Positives = 1544/1588 (97%), Gaps = 44/1588 (2%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG------------------- 761 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 762 ------------------------AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 797 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH Sbjct: 798 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 857 Query: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL Sbjct: 858 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 917 Query: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL Sbjct: 918 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 977 Query: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG Sbjct: 978 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1037 Query: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS Sbjct: 1038 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1097 Query: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 VIGVSPAVMIRSSSQDSEVSTV SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL Sbjct: 1098 VIGVSPAVMIRSSSQDSEVSTV-SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1156 Query: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD Sbjct: 1157 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1216 Query: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI Sbjct: 1217 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1276 Query: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK Sbjct: 1277 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1336 Query: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR Sbjct: 1337 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1396 Query: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL Sbjct: 1397 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1456 Query: 1501 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1560 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY Sbjct: 1457 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1516 Query: 1561 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 SVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1517 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1544 >gi|209862975 MAP-kinase activating death domain-containing protein isoform b [Homo sapiens] Length = 1565 Score = 3041 bits (7883), Expect = 0.0 Identities = 1545/1608 (96%), Positives = 1545/1608 (96%), Gaps = 63/1608 (3%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG------------------- 761 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 762 ------------------------AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 797 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK---------------- 884 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK Sbjct: 798 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP 857 Query: 885 ----GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 940 GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW Sbjct: 858 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 917 Query: 941 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1000 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL Sbjct: 918 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 977 Query: 1001 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1060 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP Sbjct: 978 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1037 Query: 1061 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQ 1120 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQ Sbjct: 1038 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQ 1097 Query: 1121 ISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSN 1180 ISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSN Sbjct: 1098 ISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSN 1157 Query: 1181 AGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDV 1240 AGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDV Sbjct: 1158 AGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDV 1217 Query: 1241 SQRVYLYEGLLGKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHD 1300 SQRVYLYEGLLGKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHD Sbjct: 1218 SQRVYLYEGLLGKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHD 1277 Query: 1301 RKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQ 1360 RKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQ Sbjct: 1278 RKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQ 1337 Query: 1361 LANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWW 1420 LANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWW Sbjct: 1338 LANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWW 1397 Query: 1421 YEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPG 1480 YEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPG Sbjct: 1398 YEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPG 1457 Query: 1481 PELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVP 1540 PELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVP Sbjct: 1458 PELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVP 1517 Query: 1541 EIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 EIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1518 EIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEEDLRTPPRPVSS 1565 >gi|209863002 MAP-kinase activating death domain-containing protein isoform j [Homo sapiens] Length = 1541 Score = 3040 bits (7882), Expect = 0.0 Identities = 1541/1588 (97%), Positives = 1541/1588 (97%), Gaps = 47/1588 (2%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG------------------- 761 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 762 ------------------------AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 797 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH Sbjct: 798 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 857 Query: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL Sbjct: 858 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 917 Query: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL Sbjct: 918 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 977 Query: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG Sbjct: 978 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1037 Query: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS Sbjct: 1038 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1097 Query: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 VIGVSPAVMIRSSSQDSEVS NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL Sbjct: 1098 VIGVSPAVMIRSSSQDSEVS----NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1153 Query: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD Sbjct: 1154 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1213 Query: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI Sbjct: 1214 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1273 Query: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK Sbjct: 1274 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1333 Query: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR Sbjct: 1334 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1393 Query: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL Sbjct: 1394 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1453 Query: 1501 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1560 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY Sbjct: 1454 QVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICY 1513 Query: 1561 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1588 SVLCLFSYVAAVHSSEEDLRTPPRPVSS Sbjct: 1514 SVLCLFSYVAAVHSSEEDLRTPPRPVSS 1541 >gi|18860873 MAP-kinase activating death domain-containing protein isoform g [Homo sapiens] Length = 1581 Score = 2980 bits (7726), Expect = 0.0 Identities = 1516/1579 (96%), Positives = 1518/1579 (96%), Gaps = 60/1579 (3%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK---------------- 884 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK Sbjct: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP 900 Query: 885 ----GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 940 GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW Sbjct: 901 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 960 Query: 941 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1000 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL Sbjct: 961 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL 1020 Query: 1001 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1060 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP Sbjct: 1021 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP 1080 Query: 1061 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASI------------------GP 1102 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASI P Sbjct: 1081 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP 1140 Query: 1103 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV 1162 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV Sbjct: 1141 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV 1200 Query: 1163 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK 1222 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK Sbjct: 1201 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK 1260 Query: 1223 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLG---------------------KERSTLWDQ 1261 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLG KERSTLWDQ Sbjct: 1261 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ 1320 Query: 1262 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS 1321 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS Sbjct: 1321 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS 1380 Query: 1322 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK 1381 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK Sbjct: 1381 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK 1440 Query: 1382 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR 1441 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR Sbjct: 1441 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR 1500 Query: 1442 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ 1501 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ Sbjct: 1501 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ 1560 Query: 1502 VTLEGINLKFMHNQVFIEL 1520 VTLEGINLKFMHNQ F++L Sbjct: 1561 VTLEGINLKFMHNQ-FLKL 1578 >gi|209862987 MAP-kinase activating death domain-containing protein isoform f [Homo sapiens] Length = 1479 Score = 2905 bits (7532), Expect = 0.0 Identities = 1474/1520 (96%), Positives = 1476/1520 (97%), Gaps = 44/1520 (2%) Query: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG Sbjct: 1 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG 60 Query: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE Sbjct: 61 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE 120 Query: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL Sbjct: 121 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL 180 Query: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL Sbjct: 181 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL 240 Query: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP Sbjct: 241 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP 300 Query: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM Sbjct: 301 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM 360 Query: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE Sbjct: 361 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE 420 Query: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN Sbjct: 421 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN 480 Query: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE Sbjct: 481 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE 540 Query: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ Sbjct: 541 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ 600 Query: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL Sbjct: 601 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL 660 Query: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE Sbjct: 661 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE 720 Query: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP 780 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG Sbjct: 721 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEG------------------- 761 Query: 781 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 840 AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST Sbjct: 762 ------------------------AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST 797 Query: 841 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 900 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH Sbjct: 798 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKH 857 Query: 901 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 960 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL Sbjct: 858 SPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVL 917 Query: 961 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 1020 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL Sbjct: 918 SKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGL 977 Query: 1021 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1080 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG Sbjct: 978 LEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATG 1037 Query: 1081 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1140 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS Sbjct: 1038 KGPKELDTRSLKEENFIASIGPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDS 1097 Query: 1141 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1200 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL Sbjct: 1098 VIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTL 1157 Query: 1201 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1260 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD Sbjct: 1158 SDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPIRTSEDVSQRVYLYEGLLGKERSTLWD 1217 Query: 1261 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1320 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI Sbjct: 1218 QMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLI 1277 Query: 1321 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1380 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK Sbjct: 1278 SYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMK 1337 Query: 1381 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1440 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR Sbjct: 1338 KQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWR 1397 Query: 1441 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1500 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL Sbjct: 1398 RNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLL 1457 Query: 1501 QVTLEGINLKFMHNQVFIEL 1520 QVTLEGINLKFMHNQ F++L Sbjct: 1458 QVTLEGINLKFMHNQ-FLKL 1476 >gi|239735519 SET binding factor 1 [Homo sapiens] Length = 1893 Score = 103 bits (257), Expect = 1e-21 Identities = 133/528 (25%), Positives = 200/528 (37%), Gaps = 127/528 (24%) Query: 10 RLLDYLVIVG-ARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSVRQRR 68 RL DY V+V HP Q ++L+R+P +D + P P + FCQP G +R Sbjct: 3 RLADYFVLVAFGPHPRGSGEGQG-QILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPER- 60 Query: 69 MSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKEGTHATCAS 128 T FV LTD ++ Y C+ F+ + +E T Sbjct: 61 ---NPPTFFVAVLTDINS-ERHYCACLTFWEPAEP--------------SQETTRV---- 98 Query: 129 EEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVLSHYPFFST 188 E TE E G D + SP A + TL + L H F Sbjct: 99 -EDATEREEEG--------DEGGQTHLSPTAP--APSAQLFAPKTLVLVSRLDHTEVFRN 147 Query: 189 FRECLYTLK-RLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSALLHDLREI 247 +Y + ++ C E ++G Sbjct: 148 SLGLIYAIHVEGLNVCLENVIG-------------------------------------- 169 Query: 248 EAWIYRLLRSPVPVSGQKRVDIEVLP---QELQPALTFALPDPSRFTLVDFPLHLPLELL 304 LL VP++G + I + Q +Q L +LP SR ++ L L Sbjct: 170 -----NLLTCTVPLAGGSQRTISLGAGDRQVIQTPLADSLP-VSRCSVA-----LLFRQL 218 Query: 305 GVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAE 364 G+ L + L EHKV+ SR Y L+ + +A+++PL Y F +P+LP A Sbjct: 219 GITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILP---AQLL 275 Query: 365 QLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLEL 424 ++L PTP+IIGV A+F + + + DV + DLD V P E + I P PE L+ Sbjct: 276 EVLSTPTPFIIGVNAAF---QAETQELLDVIVADLDGGTVTIP---ECVHIPPLPEPLQS 329 Query: 425 KKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDS 484 + H + +S+ P L L DL P P + + Sbjct: 330 QTH-----SVLSMVLDPELELA-----------------DLAFPP-----PTTSTSSLKM 362 Query: 485 VDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASR 532 D R +R F A +LQG++ +R+ P PV+ F +FL R Sbjct: 363 QDKELRAVFLRLF--AQLLQGYRWCLHVVRIHPEPVIRFHKAAFLGQR 408 >gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapiens] Length = 1906 Score = 89.7 bits (221), Expect = 2e-17 Identities = 125/533 (23%), Positives = 203/533 (38%), Gaps = 123/533 (23%) Query: 25 SDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSV---RQRRMSLRDDTSFVFTL 81 +++V+ L+ RYP ED+ F LP V FC P G + L ++FV T Sbjct: 203 TNTVSYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTG 262 Query: 82 TDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKEGTHATCASEEGGTESSESGSS 141 + YG + FY + SEE TE Sbjct: 263 ASAEKV---YGAAIQFYEPY--------------------------SEENLTEKQRLLLG 293 Query: 142 LQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVD 201 L SAD K+ S T +C+LSH+PFF FR+ L L R Sbjct: 294 LT--SADG--------------KSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRY-- 335 Query: 202 CCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPV 261 + G + L +E+ S +H + P P Sbjct: 336 ----SISGPHV------------------LPIEKHISHFMHKV-------------PFPS 360 Query: 262 SGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHK 321 + R+ +++ P + L + P S L L+ LG + + +L + EHK Sbjct: 361 PQRPRILVQLSPHD---NLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHK 417 Query: 322 VVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASF 381 +++ S + L+ A V+MI+P + P +PL P +A +L AP P+I+G+ + + Sbjct: 418 ILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALA---DVLSAPCPFIVGIDSRY 474 Query: 382 FLYKLDFKMPDDVWLVDLDSNRV--IAPTNAEVLPILPEPESLELKKHLKQALASMSLNT 439 F + P DV VD+D+N + I ILP KK K + +++ Sbjct: 475 FDL---YDPPPDVSCVDVDTNTISQIGDKKNVAWKILP-------KKPCKNLMNTLN--- 521 Query: 440 QPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNS 499 NL Q++ L RP +D + G + +D+ + A + F Sbjct: 522 ----NLH-----QQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFM-- 570 Query: 500 ANVLQGFQMHTRTLRLFPRPVVA-----FQAGSFLASRPR-QTPFAEKLARTQ 546 A++L+G++ + R + P F +FL SR R F + +TQ Sbjct: 571 ASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQ 623 >gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapiens] Length = 1863 Score = 89.7 bits (221), Expect = 2e-17 Identities = 125/533 (23%), Positives = 203/533 (38%), Gaps = 123/533 (23%) Query: 25 SDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSV---RQRRMSLRDDTSFVFTL 81 +++V+ L+ RYP ED+ F LP V FC P G + L ++FV T Sbjct: 203 TNTVSYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTG 262 Query: 82 TDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKEGTHATCASEEGGTESSESGSS 141 + YG + FY + SEE TE Sbjct: 263 ASAEKV---YGAAIQFYEPY--------------------------SEENLTEKQRLLLG 293 Query: 142 LQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVD 201 L SAD K+ S T +C+LSH+PFF FR+ L L R Sbjct: 294 LT--SADG--------------KSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRY-- 335 Query: 202 CCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPV 261 + G + L +E+ S +H + P P Sbjct: 336 ----SISGPHV------------------LPIEKHISHFMHKV-------------PFPS 360 Query: 262 SGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHK 321 + R+ +++ P + L + P S L L+ LG + + +L + EHK Sbjct: 361 PQRPRILVQLSPHD---NLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHK 417 Query: 322 VVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASF 381 +++ S + L+ A V+MI+P + P +PL P +A +L AP P+I+G+ + + Sbjct: 418 ILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALA---DVLSAPCPFIVGIDSRY 474 Query: 382 FLYKLDFKMPDDVWLVDLDSNRV--IAPTNAEVLPILPEPESLELKKHLKQALASMSLNT 439 F + P DV VD+D+N + I ILP KK K + +++ Sbjct: 475 FDL---YDPPPDVSCVDVDTNTISQIGDKKNVAWKILP-------KKPCKNLMNTLN--- 521 Query: 440 QPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNS 499 NL Q++ L RP +D + G + +D+ + A + F Sbjct: 522 ----NLH-----QQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFM-- 570 Query: 500 ANVLQGFQMHTRTLRLFPRPVVA-----FQAGSFLASRPR-QTPFAEKLARTQ 546 A++L+G++ + R + P F +FL SR R F + +TQ Sbjct: 571 ASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQ 623 >gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] Length = 1496 Score = 84.0 bits (206), Expect = 1e-15 Identities = 99/392 (25%), Positives = 151/392 (38%), Gaps = 92/392 (23%) Query: 25 SDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSV---RQRRMSLRDDTSFVFTL 81 ++++ ELL RYP ED+ FPLP V FC P G Q + + ++FV T Sbjct: 206 ANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTG 265 Query: 82 TDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKEGTHATCASEEGGTESSESGSS 141 G YG + FY +F + E+ + Sbjct: 266 A---AGDKVYGAALQFYEAFPRARLSER----------------------------QARA 294 Query: 142 LQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVD 201 L LSA RG+ RSR + + VLS +P F FR L L R Sbjct: 295 LGLLSAVE--------RGRALGGRAVRSRRA----IAVLSRWPAFPAFRAFLTFLYRYSV 342 Query: 202 CCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPV 261 RL +E S +H++ P P Sbjct: 343 SGPHRLP------------------------LEAHISHFIHNV-------------PFPS 365 Query: 262 SGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHK 321 + R+ +++ P + L P S L L+ LG + + +L +L EHK Sbjct: 366 PQRPRILVQMSPYD---NLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHK 422 Query: 322 VVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASF 381 +++ S + L+ A V+MI+PL + P IPL P +A +L AP P+I+G+ +S+ Sbjct: 423 LLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLA---DVLSAPVPFIVGIHSSY 479 Query: 382 FLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVL 413 F P DV VDLD+N + ++L Sbjct: 480 FDL---HDPPADVICVDLDTNTLFQTEEKKLL 508 >gi|94818781 DENN/MADD domain containing 4C [Homo sapiens] Length = 1673 Score = 77.4 bits (189), Expect = 1e-13 Identities = 101/395 (25%), Positives = 163/395 (41%), Gaps = 84/395 (21%) Query: 164 KAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTM 223 K S+S N T +C+LSH+PFF FR+ L + +L + P Sbjct: 65 KMVSKSIN-TNKCICLLSHWPFFEAFRKFLMFIYKL-----------SVSGPH------- 105 Query: 224 WRIFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFA 283 L +E+ S + ++ P P + R+ +++ + AL + Sbjct: 106 ------PLPIEKHISHFMQNI-------------PFPSPQRPRILVQL---SVHDALILS 143 Query: 284 LPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMI 343 P + L L LG + C +L +LLE K++L S L+ A VAMI Sbjct: 144 QPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMI 203 Query: 344 YPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNR 403 +P ++ P IPL P +A+ +L AP P+I+GV + +F P DV +DLD+N Sbjct: 204 FPFQWQCPYIPLCPLSLAA---VLSAPLPFIVGVDSRYFDL---HDPPQDVVCIDLDTNM 257 Query: 404 VIAP-----TNAEVLPILPEPESLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLL 458 + N + LP P L K L L+S+ TQ EG I + Sbjct: 258 LYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQ---------EGSAIDM-- 306 Query: 459 GRPSNDLQSTP-STEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFP 517 TP +F+ + + +++ + A +RF A++L+G++ + R + P Sbjct: 307 ---------TPIEADFS---WQKKMTQLEMEIQEAFLRFM--ASILKGYRTYLRPITEAP 352 Query: 518 RPVVA-----FQAGSFLASRPR-QTPFAEKLARTQ 546 F FL SR R F L++TQ Sbjct: 353 SNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQ 387 >gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] Length = 1274 Score = 77.0 bits (188), Expect = 1e-13 Identities = 42/132 (31%), Positives = 70/132 (53%), Gaps = 5/132 (3%) Query: 285 PDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIY 344 P PS L D+PL ELLG++ +QV TC+LLE +++L S+DY L +++ Sbjct: 259 PGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLF 318 Query: 345 PLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWL--VDLDSN 402 P ++ +P+LP AS L AP PY++G+ + + ++P + L VD+D++ Sbjct: 319 PFQWQHVYVPILP---ASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNH 375 Query: 403 RVIAPTNAEVLP 414 + P P Sbjct: 376 FIELPEEFPQFP 387 >gi|29788755 SET binding factor 2 [Homo sapiens] Length = 1849 Score = 76.6 bits (187), Expect = 2e-13 Identities = 70/252 (27%), Positives = 109/252 (43%), Gaps = 49/252 (19%) Query: 292 LVDFPLH--LPL---------ELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFV 340 L+ PLH LP+ + LG+ L + +L E+KV+ S + LS + A Sbjct: 183 LIQTPLHDSLPITGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALE 242 Query: 341 AMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLD 400 ++++PL+Y +P IP+LP A ++L +PTP+IIGV + F K D DV + DLD Sbjct: 243 SLMFPLKYSYPYIPILP---AQLLEVLSSPTPFIIGVHSVF---KTDVHELLDVIIADLD 296 Query: 401 SNRVIAPTNAEVLPILPEPESLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGR 460 + P L LPEP L Q +++SL P Sbjct: 297 GGTIKIPECIH-LSSLPEPL-------LHQTQSALSLILHP------------------- 329 Query: 461 PSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPV 520 DL+ P + +D R +R F A + QG++ + +R+ PV Sbjct: 330 ---DLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLF--AQLFQGYRSCLQLIRIHAEPV 384 Query: 521 VAFQAGSFLASR 532 + F +FL R Sbjct: 385 IHFHKTAFLGQR 396 Score = 56.2 bits (134), Expect = 2e-07 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 7/111 (6%) Query: 10 RLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSVRQRRM 69 RL DY ++VG H S ++++R+P +D + P P + FCQP G R+R Sbjct: 3 RLADYFIVVGYDHEKPGSGEGLGKIIQRFPQKDWDDTPFPQGIELFCQPGGWQLSRER-- 60 Query: 70 SLRDDTSFVFTLTDKDTGVTRYGICVNFYRS--FQKRISKEKGEGGAGSRG 118 + T FV LTD D+ Y C+ FY + + KE+ EG A G Sbjct: 61 --KQPTFFVVVLTDIDSD-RHYCSCLTFYEAEINLQGTKKEEIEGEAKVSG 108 >gi|44889475 RAB6 interacting protein 1 [Homo sapiens] Length = 1287 Score = 72.4 bits (176), Expect = 3e-12 Identities = 52/195 (26%), Positives = 96/195 (49%), Gaps = 18/195 (9%) Query: 247 IEAWIYRLLRS-PVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLG 305 +E++IY +L P+P G+ + + + P + L DFP+ ELLG Sbjct: 240 LESYIYNVLYEVPLPPPGRS-----LKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLG 294 Query: 306 VDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQ 365 V+ Q+ TC LLE +++L S+ Y L A+++P ++ +P+LP AS Sbjct: 295 VENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILP---ASLLH 351 Query: 366 LLLAPTPYIIGVPASFFLYKLDFKMPDDVWL--VDLDSNRVIAPTNAEVLPILPE-PESL 422 L AP PY++G+ ++ + ++P + L VD+D++ + P + LP+ P L Sbjct: 352 FLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPED------LPQFPNKL 405 Query: 423 ELKKHLKQALASMSL 437 E + + + L + + Sbjct: 406 EFVQEVSEILMAFGI 420 >gi|50345870 DENN/MADD domain containing 3 [Homo sapiens] Length = 1198 Score = 72.4 bits (176), Expect = 3e-12 Identities = 59/234 (25%), Positives = 102/234 (43%), Gaps = 54/234 (23%) Query: 176 SLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEE 235 ++CV+S +P++++ ++CL L L+ C + + D+ + F L Sbjct: 109 AVCVVSRFPYYNSLKDCLSCLLALLKPCKD------------FEVDSHIKDFAAKL---- 152 Query: 236 KSSALLHDLREIEAWIYRLLRSPVP-----VSGQKRVDIEVLPQELQPALTFALPDPSRF 290 L+ SP P V K + I VLP P Sbjct: 153 -----------------SLIPSPPPGPLHLVFNMKSLQI-VLPARADP----------ES 184 Query: 291 TLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMF 350 ++D LHLPL + LQ+LTCIL E ++V S D+ L++ F+A +YPL++ Sbjct: 185 PILDLDLHLPLLCFRPEKVLQILTCILTEQRIVFFSSDWALLTLVTECFMAYLYPLQWQH 244 Query: 351 PVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRV 404 P +P+L M ++APT +++G F + K D + L+++D + Sbjct: 245 PFVPILSDQML---DFVMAPTSFLMGCHLDHF--EEVSKEADGLVLINIDHGSI 293 >gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapiens] Length = 1137 Score = 61.6 bits (148), Expect = 6e-09 Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Query: 254 LLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVL 313 L+ SP P G+ LP L P SR VDF L V +++ Sbjct: 833 LMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDF--ECLFTCLSVRQLIRIF 890 Query: 314 TCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPY 373 +LLE +V+ + + LS A VA++YP + IP+LP AS ++ PTP+ Sbjct: 891 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLP---ASMIDIVCCPTPF 947 Query: 374 IIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQAL 432 ++G+ +S L KL ++ +V+L S+R I + E +LP +L+ L+QAL Sbjct: 948 LVGLLSS-SLPKLKELPVEEALMVNLGSDRFIRQMDDED-TLLPR----KLQAALEQAL 1000 >gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapiens] Length = 1137 Score = 61.6 bits (148), Expect = 6e-09 Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Query: 254 LLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVL 313 L+ SP P G+ LP L P SR VDF L V +++ Sbjct: 833 LMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDF--ECLFTCLSVRQLIRIF 890 Query: 314 TCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPY 373 +LLE +V+ + + LS A VA++YP + IP+LP AS ++ PTP+ Sbjct: 891 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLP---ASMIDIVCCPTPF 947 Query: 374 IIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQAL 432 ++G+ +S L KL ++ +V+L S+R I + E +LP +L+ L+QAL Sbjct: 948 LVGLLSS-SLPKLKELPVEEALMVNLGSDRFIRQMDDED-TLLPR----KLQAALEQAL 1000 >gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo sapiens] Length = 717 Score = 61.6 bits (148), Expect = 6e-09 Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Query: 254 LLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVL 313 L+ SP P G+ LP L P SR VDF L V +++ Sbjct: 413 LMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDF--ECLFTCLSVRQLIRIF 470 Query: 314 TCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPY 373 +LLE +V+ + + LS A VA++YP + IP+LP AS ++ PTP+ Sbjct: 471 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLP---ASMIDIVCCPTPF 527 Query: 374 IIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQAL 432 ++G+ +S L KL ++ +V+L S+R I + E +LP +L+ L+QAL Sbjct: 528 LVGLLSS-SLPKLKELPVEEALMVNLGSDRFIRQMDDED-TLLPR----KLQAALEQAL 580 >gi|121949817 DENN/MADD domain containing 2C [Homo sapiens] Length = 871 Score = 58.5 bits (140), Expect = 5e-08 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 12/172 (6%) Query: 249 AWIYRLLRS----PVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELL 304 A +Y +RS P P G+ LP ++ P SR VDF + L Sbjct: 562 ALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLF--KCL 619 Query: 305 GVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAE 364 V ++V +LLE +V+ + + LS A VA +YP + IP+LP AS Sbjct: 620 SVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLP---ASMI 676 Query: 365 QLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN--AEVLP 414 ++ +PTP++IG+ S L +L ++V +VDL +++ + + E+LP Sbjct: 677 DIVCSPTPFLIGI-LSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILP 727 >gi|154813195 DENN/MADD domain containing 2A [Homo sapiens] Length = 1009 Score = 58.2 bits (139), Expect = 6e-08 Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 7/177 (3%) Query: 254 LLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVL 313 ++ +P P G+ + LP + P SR VDF L V + V Sbjct: 702 VMEAPFPALGKTILVKNFLPGSGTEVIELCRPLDSRLEHVDF--ESLFSSLSVRHLVCVF 759 Query: 314 TCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPY 373 +LLE +V+ + + LS A VA+IYP + IP+LP M ++ +PTP+ Sbjct: 760 ASLLLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMV---DIVCSPTPF 816 Query: 374 IIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430 +IG+ +S + + ++V +VDL ++R + + E ILP + L+ L+Q Sbjct: 817 LIGLLSSSLPLLRELPL-EEVLVVDLVNSRFLRQMDDED-SILPRKLQVALEHILEQ 871 Score = 31.2 bits (69), Expect = 8.3 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 10 RLLDYLVIVGARHPSSDSVAQTPELLRRYP--LEDHTEFPLPPDVVFFCQPEGCLSVRQR 67 +L +Y V+V H A PEL +++P LE +F + P+ C + Sbjct: 563 QLFEYFVVVSL-HKKQAGAAYVPELTQQFPLKLERSFKFMREAEDQLKAIPQFCFPDAKD 621 Query: 68 RMSLRDDTS--FVFTLTDKDTGVTRYGIC 94 + ++ TS F F LT +D G R+G C Sbjct: 622 WVPVQQFTSETFSFVLTGED-GSRRFGYC 649 >gi|113205087 DENN/MADD domain containing 1C [Homo sapiens] Length = 801 Score = 58.2 bits (139), Expect = 6e-08 Identities = 70/270 (25%), Positives = 117/270 (43%), Gaps = 36/270 (13%) Query: 168 RSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLV--DCCSERLLGKKLGIPRGVQRDTMWR 225 R R T + LC+LSH P+F F + L T+ L+ D +E + + Sbjct: 86 RLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVTEA-------------EELLQN 132 Query: 226 IFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALP 285 +F SL + S L L S V VS + + +P F P Sbjct: 133 LFQQSLSGPQASVGLE-------------LGSGVTVSSGQGIPPPTRGNS-KPLSCFVAP 178 Query: 286 DPSRFTLVDFPLHLPLELLGV--DACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMI 343 D R + +L ++ V + + + +L E +V+L + + L+ V A A++ Sbjct: 179 DSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALL 238 Query: 344 YPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNR 403 YP+ + +IP LP + AP PY+IGV AS ++ K +DV ++++D+N Sbjct: 239 YPMRWEHVLIPTLPPHLL---DYCCAPMPYLIGVHAS-LAERVREKALEDVVVLNVDAN- 293 Query: 404 VIAPTNAEVLPILPEPESLELKKHLKQALA 433 + T +V + P+ SL + K ALA Sbjct: 294 TLETTFNDVQALPPDVVSLLRLRLRKVALA 323 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 56.2 bits (134), Expect = 2e-07 Identities = 76/329 (23%), Positives = 124/329 (37%), Gaps = 19/329 (5%) Query: 597 SNSQLAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPN 656 SNS + S S+ +D S SDS D DSS+S SS D + D + + + Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743 Query: 657 VDPLTHAALGDASE----VEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPST 712 D + D+S+ + + ++ + S +S N SS S+ +S+S + Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803 Query: 713 VIHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPY 772 +S+ +DS++ D + S S S + D + G S D+ Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS- 862 Query: 773 FEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPN 832 + D S + S N + + +SDSD+ SDS SS + Sbjct: 863 -------NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS-SDSSNSSDS 914 Query: 833 STVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVD 892 S SN+S S SS N S S + S+ + + + + S N D Sbjct: 915 SDSSNSSDSS----ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970 Query: 893 QKSSVIKHSPTVKREPPSPQGRSSNSSEN 921 SS S + S SS+SS++ Sbjct: 971 SNSS--DSSDSSNSSDSSDSSDSSDSSDS 997 Score = 51.2 bits (121), Expect = 8e-06 Identities = 63/324 (19%), Positives = 123/324 (37%), Gaps = 7/324 (2%) Query: 598 NSQLAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNV 657 +S +++ S SDS+ +D SDS D D S SS SS S+ + D+ + Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622 Query: 658 DPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGA 717 + + D+S+ + + + + +S++S + SS S+ +S S + Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682 Query: 718 NSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQY 777 +S +DS++ D + S S + D + + + Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742 Query: 778 GFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSN 837 + + S + S + + + +SDS+ S+S SS +S S+ Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802 Query: 838 TSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSV 897 +S S +S ++S+ S S+ + + + + + S G+ D SS Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS-----DSDSS- 856 Query: 898 IKHSPTVKREPPSPQGRSSNSSEN 921 S + S SSNSS++ Sbjct: 857 -NRSDSSNSSDSSDSSDSSNSSDS 879 Score = 47.4 bits (111), Expect = 1e-04 Identities = 73/339 (21%), Positives = 129/339 (38%), Gaps = 25/339 (7%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDS-------GSDSMDYDDSSSSYSSLGDFVSEMMKC 648 DS+S + + S DSDS + DS SDS D DSS S S S+ Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627 Query: 649 DINGDTPNVDPLTHAALGDASEV----EIDELQNQKEAEEPGPDSENSQENPPLRSSSST 704 D+ + D + ++ ++S+ + + N + + S++S + SS+S+ Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687 Query: 705 TASSSPSTVIHGANSEPADSTEMD--DKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGS 762 +S S + +S+ +DS++ D D + S S + S+ ++ + S Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747 Query: 763 VRRRIYDNPYFEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDA 822 D+ D + +S S N + NS +SDS Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD-------SSNSSDSNDSSNSSD-SSDSSN 799 Query: 823 ESDSRASSPNSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPS 882 SDS SS +S S++S ++S + S++ S S+ + + + + S Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859 Query: 883 LKGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSEN 921 N D S S + S SSNSS++ Sbjct: 860 DSSNSSDSSDSSDS----SNSSDSSDSSDSNESSNSSDS 894 Score = 46.6 bits (109), Expect = 2e-04 Identities = 71/333 (21%), Positives = 119/333 (35%), Gaps = 15/333 (4%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTP 655 DS++ + S SDS + DS S D S SS SS S+ + D+ Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819 Query: 656 NVDPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIH 715 + + + D+S+ + G DS++S + SS S+ +S S ++ Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879 Query: 716 GANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEP 775 +S+ +S+ D + S S S + D + + S DN Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD--SSNSSDSSESSNSSDNSNSSD 937 Query: 776 QYGFPPEED-------EDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRA 828 D D S + S N + NS SDS SDS Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS----SDSSDSSDSSD 993 Query: 829 SSPNSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRR 888 SS +S SN+S S +S+ + S++ S S+ + + + + + S + Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSN--SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051 Query: 889 ALVDQKSSVIKHSPTVKREPPSPQGRSSNSSEN 921 + S S + S SS+SSE+ Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084 Score = 46.2 bits (108), Expect = 3e-04 Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 7/272 (2%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDSG--SDSMDYDDSSSSYSSLGDFVSEMMKCDINGD 653 DS+ + S SDS + DS SDS D DSS S S D + D + Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDS 1066 Query: 654 TPNVDPLTHAALGDASEV-EIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPST 712 + + D + D+SE + + N ++ + S++S + SS S+ +S+S + Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126 Query: 713 VIHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPY 772 +S+ +DS+ D + S S S+ ++ + S D+ Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD-SSDSSDSSDSSDSSNSSDSSD 1185 Query: 773 FEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPN 832 D + +S S S + +S +SDS+ SDS SS + Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSNESSDSSDSSDS 1243 Query: 833 STVSNTSTEGFGGIMSFASSLYRNHSTSFSLS 864 S SN+S S ++S + S S S S Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275 Score = 46.2 bits (108), Expect = 3e-04 Identities = 61/269 (22%), Positives = 103/269 (38%), Gaps = 14/269 (5%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDS--GSDSMDYDDSSSSYSSLGDFVSEMMKCDINGD 653 DS+ + S SDS + DS SDS D DSS S S D D + Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS-SESSDSSDSSNSSDSSDS 1099 Query: 654 TPNVDPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTV 713 + + D + D+S + + N ++ + S++S + SS S+ +S S + Sbjct: 1100 SDSSDSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157 Query: 714 IHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNV--DRRQAEIGEGSVRRRIYDNP 771 +S+ +DS++ D + S S S+ ++ + S D+ Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217 Query: 772 YFEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSP 831 D +E +S S S N + +S SDS+ ESDS++ S Sbjct: 1218 DSSDSSDSSDSSDSNESSDSSDSSDSSD-SSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276 Query: 832 NSTVSNTSTEGFGGIMSFASSLYRNHSTS 860 N + + ++ S + NHSTS Sbjct: 1277 NGNNNGSDSD------SDSEGSDSNHSTS 1299 Score = 45.4 bits (106), Expect = 4e-04 Identities = 65/314 (20%), Positives = 119/314 (37%), Gaps = 10/314 (3%) Query: 610 ERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPLTHAALGDAS 669 E D++S D+ +S + D+ + S G +E D DT N D + G+ Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDSKG---AEDDDSDSTSDTNNSDSNGNGNNGNDD 536 Query: 670 EVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSEPADSTEMDD 729 + D + + ++ DS++S + SS S+ + SS S ++S +DS++ D Sbjct: 537 NDKSDSGKGKSDSS----DSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSD 592 Query: 730 KAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFPPEEDEDEQG 789 + S S S + D + + + D+ + + D Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652 Query: 790 ESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRAS--SPNSTVSNTSTEGFGGIM 847 S + S + + + + +SDS SDS S S NS+ S+ S++ Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712 Query: 848 SFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKHSPTVKRE 907 S +S ++S+ SN + + + + S N D S S + Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS-SNSSDSSDSS 771 Query: 908 PPSPQGRSSNSSEN 921 S SSNSS++ Sbjct: 772 DSSDSSDSSNSSDS 785 Score = 44.7 bits (104), Expect = 7e-04 Identities = 75/337 (22%), Positives = 123/337 (36%), Gaps = 38/337 (11%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDSG-----SDSMDYDDSSSSYSSLGDF----VSEMM 646 D N + DSDS + +S SDS D +SSS S D S+ Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594 Query: 647 KCDINGDTPNVDPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTA 706 D + + + D + D+S+ D + ++E DS++ ++ SS S+ Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSD-SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653 Query: 707 SSSPSTVIHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRR 766 S S + +S+ +DS++ D ++ S S SN ++ + S Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN-SSESSDSSDSS---- 708 Query: 767 IYDNPYFEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDS 826 + D + +S S S N + NS SDS SDS Sbjct: 709 ---------------DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS----SDSSDSSDS 749 Query: 827 RAS--SPNSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLK 884 S S +S+ S+ S++ S SS N S S SN + + + + S Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809 Query: 885 GNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSEN 921 + D SS S + S SS+SS++ Sbjct: 810 SDSSDSSDSDSS--NSSDSSNSSDSSDSSNSSDSSDS 844 Score = 43.9 bits (102), Expect = 0.001 Identities = 58/261 (22%), Positives = 96/261 (36%), Gaps = 6/261 (2%) Query: 606 SVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPLTHAAL 665 S +SDS ++G+D D DS S D S+ + D+ + + Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSD--SDSSDSSNSSDSSDSSDSDSSDS 574 Query: 666 GDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSEPADST 725 +S+ + + + ++ DS NS ++ SS ++ SS S ++ +DS+ Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634 Query: 726 EMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFPPEED- 784 + D K+ S S S S+ + + S D+ D Sbjct: 635 DSDSKSDSSDSNSSDSSDNS--DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692 Query: 785 EDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTSTEGFG 844 D S + S + + NS SDS SDS SS NS+ S+ S++ Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS-NSSDSSDSSDSSN 751 Query: 845 GIMSFASSLYRNHSTSFSLSN 865 S SS N S S S+ Sbjct: 752 SSDSSDSSDSSNSSDSSDSSD 772 Score = 41.2 bits (95), Expect = 0.008 Identities = 52/244 (21%), Positives = 93/244 (38%), Gaps = 7/244 (2%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTP 655 DS+ + S SDS + DS S D S+SS SS S+ + D+ Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046 Query: 656 NVDPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIH 715 + + ++ S D + ++ + S++S+ + SS+S+ +S S + Sbjct: 1047 DSSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105 Query: 716 GANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEP 775 +S+ +DS++ D + S S SN ++ + S D+ Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN----SSDSSDSSESSDSSDSSDSSD 1161 Query: 776 QYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTV 835 D + +S S S + +S +SDS SDS SS +S Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDS 1219 Query: 836 SNTS 839 S++S Sbjct: 1220 SDSS 1223 Score = 40.8 bits (94), Expect = 0.011 Identities = 55/245 (22%), Positives = 92/245 (37%), Gaps = 27/245 (11%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTP 655 DS+ + S SDS + DS SDS D DSS S S S D + + Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSNSSDSS----DSSDSSD 1134 Query: 656 NVDPLTHAALGDASE-VEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVI 714 + D + D+SE + + + ++ + S++S + SS S+ +S S + Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194 Query: 715 HGANSEPADSTEMDDKAAVGVSKPLPSVPPS--IGKSNVDRRQAEIGEGSVRRRIYDNPY 772 +S+ +DS++ D + S S SN ++ + S D+ Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS- 1253 Query: 773 FEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPN 832 + D +S SQ SGN + SD++SDS S N Sbjct: 1254 -------DSSDSSDSTSDSNDESDSQSKSGNGNN-----------NGSDSDSDSEGSDSN 1295 Query: 833 STVSN 837 + S+ Sbjct: 1296 HSTSD 1300 Score = 39.3 bits (90), Expect = 0.031 Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 4/108 (3%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRS---SSQDSEVSTVVSNS 1166 D + S S+DS S SS DS G RS +S DS S+ SNS Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876 Query: 1167 SGETLGADSDLSSNAGDGPGGEGSVHLASS-RGTLSDSEIETNSATST 1213 S + +DS+ SSN+ D S SS SDS +NS+ S+ Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924 Score = 38.5 bits (88), Expect = 0.052 Identities = 55/247 (22%), Positives = 95/247 (38%), Gaps = 13/247 (5%) Query: 596 DSNSQLAEALSVPPERDSDSEPTDDS--GSDSMDYDDSSSSYSSLGDFVSEMMKCDINGD 653 DS+ + S SDS + DS SDS D DSS S +S S D + Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS----DSSNS 1030 Query: 654 TPNVDPLTHAALGDASE-VEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPST 712 + + D + D+S+ + + N ++ + S++S + SS S+ +S S + Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090 Query: 713 VIHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPY 772 +S+ +DS++ D + S S S+ ++ + S D+ Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD----SSDSSDSSDSSNSSDSSD 1146 Query: 773 FEPQYGFPPEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPN 832 D + +S S S + +S +SDS SDS SS + Sbjct: 1147 SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS--DSSDSSDSSDSSDSSDS 1204 Query: 833 STVSNTS 839 S S++S Sbjct: 1205 SDSSDSS 1211 Score = 37.7 bits (86), Expect = 0.089 Identities = 71/324 (21%), Positives = 117/324 (36%), Gaps = 42/324 (12%) Query: 618 TDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPLTHAALGDASEVEIDELQ 677 ++ G DS D+DD S GD + + + N D + ++ GDAS + Sbjct: 445 SNSDGYDSYDFDDKSMQ----GDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKD 500 Query: 678 NQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSEPADSTEMDDKAAVGVSK 737 N ++ G + ++S S+S T S S N + + +DK+ G K Sbjct: 501 NGNGSDSKGAEDDDSD------STSDTNNSDS--------NGNGNNGNDDNDKSDSGKGK 546 Query: 738 PLPSVPPSIGKSN-VDRRQAEIGEGSVRRRIYDNPYFEPQYGFPPEED------EDEQGE 790 S S SN D + + S D+ + + D + + Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606 Query: 791 SYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRAS-------------SPNSTVSN 837 S S S + K S +SDSD++SDS S S NS+ S+ Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666 Query: 838 TSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSV 897 S++ S +SS N S S S+ + + E + S + D +S Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSD----SSNSSESSDSSDSSDSDSSDSSDSSNSN 722 Query: 898 IKHSPTVKREPPSPQGRSSNSSEN 921 S + S SS+SS++ Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDS 746 Score = 37.4 bits (85), Expect = 0.12 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 6/105 (5%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S S DS S+ S+SS + G+ Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851 Query: 1174 DSDLS-----SNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DSD S SN+ D S + + S + SDS +NS+ S+ Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS-SDSNESSNSSDSS 895 Score = 37.0 bits (84), Expect = 0.15 Identities = 28/99 (28%), Positives = 44/99 (44%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS + S S DS S+ S+SS + + Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 DS SSN+ D S ++S + + S+ +S +S Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034 Score = 36.6 bits (83), Expect = 0.20 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 4/101 (3%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS + S+S DS S S+SS + + Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS---SDSSDSSNSS 839 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGT-LSDSEIETNSATST 1213 DS SS++ DG + S SS + SDS +NS+ S+ Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880 Score = 36.6 bits (83), Expect = 0.20 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Query: 1119 SQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLS 1178 S S+DS S SS +S + SS DS S+ S+SS + +DS S Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926 Query: 1179 SNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 SN+ D S + + S SDS +NS+ S+ Sbjct: 927 SNSSDNSNSSDSSNSSDS----SDSSDSSNSSDSS 957 Score = 36.6 bits (83), Expect = 0.20 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Query: 1119 SQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLS 1178 S S+DS S SS + S S S S DS S+ SNSS + +DS S Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015 Query: 1179 SNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 SN+ D S + + S + SDS ++S+ S+ Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDS-SDSSDSSDSSDSS 1049 Score = 36.6 bits (83), Expect = 0.20 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 11/126 (8%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S DS S+ S+SS + Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDS-----------SDSSDSSDSSDSSDSSDSNESS 1235 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSP 1233 DS SS++ D S + S + SDS E++S + + G + + + S Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295 Query: 1234 IRTSED 1239 TS+D Sbjct: 1296 HSTSDD 1301 Score = 36.2 bits (82), Expect = 0.26 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 1114 TEEKKSQISADSGVSLTS-SSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLG 1172 +E S S+DS S +S SS DS S S+S DS S+ SNSS + Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758 Query: 1173 ADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 +DS SS++ D S S SDS +NS+ S+ Sbjct: 759 SDSSNSSDSSDSSDSSDS----SDSSNSSDSNDSSNSSDSS 795 Score = 35.8 bits (81), Expect = 0.34 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D +++ S S+DS S SS DS S + S S DS+ + S+S+ Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKL 1229 +SD SS++ + S + S + S S+ +S +S ++S + S Sbjct: 649 DSSDNSD-SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS 707 Query: 1230 AGSPIRTSEDVS 1241 + S S D S Sbjct: 708 SDSDSSDSSDSS 719 Score = 35.8 bits (81), Expect = 0.34 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D ++ + + S+DS S +S S + S S S S DS S+ S+SS Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 + +DS SSN+ D S + S + SDS ++S+ S+ Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNS-SDSSNSSDSSDSS 813 Score = 35.4 bits (80), Expect = 0.44 Identities = 28/104 (26%), Positives = 45/104 (43%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D +++ S S+DS S S S ++ S S + SS DS S+ S+SS Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 + +DS SS++ D SS ++NS+ S+ Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651 Score = 35.4 bits (80), Expect = 0.44 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 1/100 (1%) Query: 1115 EEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGAD 1174 E S S+DS S S S + S S S S +S ++ S+SS + +D Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946 Query: 1175 SDLSSNAGDGPGGEGSVHLA-SSRGTLSDSEIETNSATST 1213 S SSN+ D S + + SS SDS +NS+ S+ Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986 Score = 35.4 bits (80), Expect = 0.44 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 13/100 (13%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S+S DS S+ SNSS + + Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDS-----------SNSSDSSDSSDSSNSSDSSNSS 960 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D + S +S+ SDS ++S+ S+ Sbjct: 961 DSSNSSDSSDSNSSDSSD--SSNSSDSSDSSDSSDSSDSS 998 Score = 35.4 bits (80), Expect = 0.44 Identities = 32/101 (31%), Positives = 44/101 (43%), Gaps = 6/101 (5%) Query: 1113 ETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLG 1172 ++ + S S+DS S SS DS S S S DS S+ SNSS + Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDS--SDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024 Query: 1173 ADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 +DS SS++ D S S SDS +NS+ S+ Sbjct: 1025 SDSSNSSDSSDSSDSSDS----SDSSDSSDSSDSSNSSDSS 1061 Score = 35.0 bits (79), Expect = 0.58 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 16/135 (11%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S+S DS S+ S+SS + + Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDS-----------SNSSDSSDSSDSSDSSDSSNSS 783 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGT-----LSDSEIETNSATSTIFGKAHSLKPSIKEK 1228 DS+ SSN+ D S ++S + SDS+ +S +S + S S Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843 Query: 1229 LAGSPIRTSEDVSQR 1243 + S + D S R Sbjct: 844 SSDSSDGSDSDSSNR 858 Score = 34.7 bits (78), Expect = 0.75 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 3/104 (2%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D ++ S S+DS S SS DS S S S DS S+ SNSS Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS--SNSSDSSDSSDSSDSSNSSDSSNSSDS 1027 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 + +DS SS++ D S + S + SDS ++S+ S+ Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNS-SDSSDSSDSSDSS 1070 Score = 34.3 bits (77), Expect = 0.99 Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 4/105 (3%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSS-SQDSEVSTVVSNSSG 1168 D +++ S S+DS S + SS +D DS + + SS S DS S+ S+S Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624 Query: 1169 ETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 ++ ++SD S + + + +S SDS +NS+ S+ Sbjct: 625 DSSKSESDSSDSDSKSDSSDSN---SSDSSDNSDSSDSSNSSNSS 666 Score = 34.3 bits (77), Expect = 0.99 Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 14/106 (13%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D ++ S ++DS S SS+ DS S S DS S+ SNSS Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS-----------SDSSDSSSSSDSSNSSDS 689 Query: 1170 TLGADSDLS---SNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 + +DS S S++ D + S SS SDS+ +S +S Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735 Score = 34.3 bits (77), Expect = 0.99 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 3/104 (2%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D ++ + S+DS S SS DS S + S+S DS S+ SNSS Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS--SDSSSSSDSSNSSDSSDSSDSSNSSES 701 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 + +DS S++ D S S SDS +NS+ S+ Sbjct: 702 SDSSDSS-DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744 Score = 34.3 bits (77), Expect = 0.99 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 8/106 (7%) Query: 1114 TEEKKSQISADSGVSLTSS-----SQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSG 1168 ++ S S+DS S SS S +D DS S + SS DS S+ S+SS Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS-SDSSNSNSSDSDSSNSSDSSDSSN 739 Query: 1169 ETLGADSDLSSNAGDGPGGEGSVHLASSRGT--LSDSEIETNSATS 1212 + +DS SSN+ D S + + S + SDS +NS+ S Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785 Score = 33.9 bits (76), Expect = 1.3 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 5/100 (5%) Query: 1113 ETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLG 1172 E++ S +DS S +S S S S S S DS S+ S+SS + Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689 Query: 1173 ADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 +DS SSN+ E S SS SDS +NS +S Sbjct: 690 SDSSDSSNSS-----ESSDSSDSSDSDSSDSSDSSNSNSS 724 Score = 33.9 bits (76), Expect = 1.3 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS+ DS S S DS S+ S+SS + + Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDS-----------SDSSDSSDSSDSSDSSDSSESS 1085 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTL--SDSEIETNSATST 1213 DS SSN+ D S + S + SDS +NS+ S+ Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127 Score = 33.5 bits (75), Expect = 1.7 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 7/108 (6%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D ++ + S S+DS S SS DS + S DS + SNSS Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS---DGSDSDSSNRSDSSNSSDS 867 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLA----SSRGTLSDSEIETNSATST 1213 + +DS SS++ D S + + SS + SDS +NS+ S+ Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915 Score = 33.5 bits (75), Expect = 1.7 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 12/100 (12%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S+S DS S+ SNSS + + Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSSDS-----------SNSSDSSNSSDSSNSSDSSDSS 1037 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D S + + S + SDS ++S+ S+ Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSDSS 1076 Score = 33.5 bits (75), Expect = 1.7 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S S DS S+ S+SS + + Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D S + S + SDS +NS+ S+ Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDS-SDSSDSSNSSDSS 1184 Score = 33.1 bits (74), Expect = 2.2 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 1/100 (1%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S S+ DS + + S S +S S+ SNSS + + Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 +S +SN+ D S + S + SDS ++S+ S+ Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNS-SDSSNSSDSSNSS 966 Score = 32.7 bits (73), Expect = 2.9 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 9/104 (8%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D G+ + S + + + SS +D DS +SS DS+ S S+ S + Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS--------NSSSDSDSSDSDSSDSSD 592 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDS-EIETNSATS 1212 + +DS SS++ D S + S + SDS + E++S+ S Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636 Score = 32.7 bits (73), Expect = 2.9 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S +S S SS DS S S S +S S+ SNSS + + Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSE-IETNSATST 1213 DS SS++ D S ++S + + S+ ++NS+ S+ Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977 Score = 32.7 bits (73), Expect = 2.9 Identities = 26/99 (26%), Positives = 43/99 (43%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S++S S SS DS + SS +S S+ SNSS + + Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 DS SS++ D S + S + + S+ +S +S Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028 Score = 32.7 bits (73), Expect = 2.9 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS+ DS S S DS S+ S+SS + + Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDS-----------SDSSDSSDSSDSSDSSDSSNSS 1058 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D S + S + SDS +NS+ S+ Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSES-SDSSDSSNSSDSS 1097 Score = 32.7 bits (73), Expect = 2.9 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S S DS S+ S+SS + + Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDS--SDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D S + S + SDS +NS+ S+ Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSDSSNSSDSS 1145 Score = 32.7 bits (73), Expect = 2.9 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S S DS S+ S+SS + + Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D S + S + SDS +NS+ S+ Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDS-SDSSDSSNSSDSS 1253 Score = 32.3 bits (72), Expect = 3.7 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSS-SQDSEVSTVVSNSSGETLG 1172 ++ S S+DS S SS+ DS + + SS S DS+ S +S+ + Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725 Query: 1173 ADSDLSSNAGDGPGGEGSVHLASSRGT--LSDSEIETNSATST 1213 +DS SS++ D S + S + SDS +NS+ S+ Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768 Score = 32.3 bits (72), Expect = 3.7 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 11/94 (11%) Query: 1119 SQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLS 1178 S S+DS S SS DS S+S DS S+ S+SS + +DS S Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDS-----------SNSSDSSDSSDSSDSSDSSDSSDSSDS 1054 Query: 1179 SNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 SN+ D S + S + S+ +S +S Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088 Score = 32.3 bits (72), Expect = 3.7 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S S DS S+ S+SS + + Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDS--SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SSN+ D S + S + SDS ++S+ S+ Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDS-SDSSDSSDSSDSS 1172 Score = 32.3 bits (72), Expect = 3.7 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S DS S+ S+SS + + Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES-----SDSSDSSDSSDSSDSSDSSDSS 1172 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SSN+ D S + S + SDS ++S+ S+ Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSS 1211 Score = 32.3 bits (72), Expect = 3.7 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 9/100 (9%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S S+DS S SS DS S S DS S+ SNSS + + Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDS--------SDSSDSSDSSDSSNSSDSSDSS 1187 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DS SS++ D S + S + SDS ++S+ S+ Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSS 1226 Score = 32.0 bits (71), Expect = 4.9 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 12/100 (12%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 + S S+DS S SSS +S S S DS S+ S SS + + Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNS-----------SDSSDSSDSSNSSESSDSSDSS 708 Query: 1174 DSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATST 1213 DSD SS++ D S +S+ SDS ++S+ S+ Sbjct: 709 DSD-SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747 Score = 32.0 bits (71), Expect = 4.9 Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 4/107 (3%) Query: 1110 DLGETEEKKSQISADSGVSLTSS-SQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSG 1168 D ++ S S+DS S SS S + +S S S S DS S+ SNSS Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961 Query: 1169 ETLGADSDLSSNAGDGPGGEGSVHLASSRGT--LSDSEIETNSATST 1213 + +DS SN+ D S + S + SDS +NS+ S+ Sbjct: 962 SSNSSDSS-DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007 Score = 32.0 bits (71), Expect = 4.9 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%) Query: 1119 SQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSS-SQDSEVSTVVSNSSGETLGADSDL 1177 S S+DS S SS DS + SS S DS S+ S+SS + +DS Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119 Query: 1178 SSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 SSN+ D S + S + S+ +S +S Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154 Score = 31.6 bits (70), Expect = 6.4 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 3/132 (2%) Query: 1110 DLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGE 1169 D + S S+DS S SS+ DS S S S DS S+ S+SS Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS--SDSNESSNSSDSSDSSNSSD-SDSSDS 908 Query: 1170 TLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKL 1229 + +DS SSN+ D S ++S + + S+ +S +S ++S S Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968 Query: 1230 AGSPIRTSEDVS 1241 + S S D S Sbjct: 969 SDSNSSDSSDSS 980 Score = 31.2 bits (69), Expect = 8.3 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 2/101 (1%) Query: 1114 TEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGA 1173 ++ S +DS S S S + S S S S DS S+ S+SS + + Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901 Query: 1174 DSDLS--SNAGDGPGGEGSVHLASSRGTLSDSEIETNSATS 1212 DSD S SN+ D S + S + +S +S +S Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942 >gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo sapiens] Length = 426 Score = 55.8 bits (133), Expect = 3e-07 Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 45/261 (17%) Query: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236 LC+LS+ P+F + + L TL L +E Sbjct: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122 Query: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDI---EVLPQE--LQPALTFALPDPSRFT 291 + L LR + +PV +S + + I +VL + L P F PD + Sbjct: 123 ENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDVTGLP 182 Query: 292 LVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYM 349 + +L + VD LQ+ +L E ++V+ S + L+ + A++YP+ + Sbjct: 183 TIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQ 242 Query: 350 FPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN 409 IP+LP + AP PY+IG+ +S + ++ K +DV ++++D+N + +P + Sbjct: 243 HIYIPVLPPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFS 298 Query: 410 AEVLPILPEPESLELKKHLKQ 430 L LP LK LK+ Sbjct: 299 D--LNNLPSDVVSALKNKLKK 317 >gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo sapiens] Length = 755 Score = 52.4 bits (124), Expect = 3e-06 Identities = 59/254 (23%), Positives = 105/254 (41%), Gaps = 51/254 (20%) Query: 177 LCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK 236 LC+LS+ P+F + + L TL L +E Sbjct: 95 LCILSYLPWFEVYYKLLNTL--------------------------------ADYLAKEL 122 Query: 237 SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFP 296 + L LR L PVP + V++ V + P +T P L ++ Sbjct: 123 ENDLNETLRS-------LYNHPVPKANTP-VNLSVHSYFIAPDVTGLPTIPESRNLTEY- 173 Query: 297 LHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLL 356 + V+ LQ+ +L E ++V+ S + L+ + A++YP+ + IP+L Sbjct: 174 ----FVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVL 229 Query: 357 PTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPIL 416 P + AP PY+IG+ +S + ++ K +DV ++++D+N + +P + L L Sbjct: 230 PPHLL---DYCCAPMPYLIGIHSS-LIERVKNKSLEDVVMLNVDTNTLESPFSD--LNNL 283 Query: 417 PEPESLELKKHLKQ 430 P LK LK+ Sbjct: 284 PSDVVSALKNKLKK 297 >gi|21361991 DENN/MADD domain containing 2D [Homo sapiens] Length = 471 Score = 51.2 bits (121), Expect = 8e-06 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 6/146 (4%) Query: 254 LLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVL 313 L + P G+ +P ++ P S VDF L L + LQ+ Sbjct: 191 LREAAFPAPGKTVTLKSFIPDSGTEFISLTRPLDSHLEHVDFSSLL--HCLSFEQILQIF 248 Query: 314 TCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPY 373 +LE K++ + + LS + A A++YP + IP++P + + + PTP+ Sbjct: 249 ASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLAT---VCCPTPF 305 Query: 374 IIGVPASFFLYKLDFKMPDDVWLVDL 399 ++GV F +D M ++V LV+L Sbjct: 306 MVGVQMRFQQEVMDSPM-EEVLLVNL 330 >gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens] Length = 559 Score = 48.9 bits (115), Expect = 4e-05 Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%) Query: 282 FALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSMSVMAF 339 F +PD + +L + VD L + +L E ++++ + L+ + Sbjct: 155 FTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGS 214 Query: 340 VAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDL 399 AM+YP+ + IP+LP + AP PY+IG+ S + K+ DDV ++++ Sbjct: 215 AAMLYPMYWQHVYIPVLPPHLL---DYCCAPMPYLIGIHLS-LMEKVRNMALDDVVILNV 270 Query: 400 DSNRVIAPTNAEVLPILPEPESLELKKHLKQ 430 D+N + P + L LP LK LK+ Sbjct: 271 DTNTLETP--FDDLQSLPNDVISSLKNRLKK 299 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,828,599 Number of Sequences: 37866 Number of extensions: 3144876 Number of successful extensions: 14741 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 191 Number of HSP's that attempted gapping in prelim test: 13246 Number of HSP's gapped (non-prelim): 1070 length of query: 1588 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1472 effective length of database: 13,855,062 effective search space: 20394651264 effective search space used: 20394651264 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.