Guide to the Human Genome
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Name: DENND2D Sequence: fasta or formatted (471aa) NCBI GI: 21361991
Description:

DENN/MADD domain containing 2D

Referenced in:

Additional Interaction Domain Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         26           4
 C cysteine            2.3         11           2
 D aspartate           3.2         15           2
 E glutamate           8.7         41           4
 F phenylalanine       7.2         34           2
 G glycine             5.9         28           2
 H histidine           2.3         11           1
 I isoleucine          5.5         26           2
 K lysine              6.8         32           3
 L leucine            10.8         51           2
 M methionine          1.7          8           1
 N asparagine          2.3         11           1
 P proline             6.4         30           2
 Q glutamine           6.2         29           2
 R arginine            5.3         25           2
 S serine              6.6         31           2
 T threonine           3.8         18           1
 V valine              6.2         29           2
 W tryptophan          0.4          2           1
 Y tyrosine            2.8         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DENN/MADD domain containing 2D 
ST5                   0.436   suppression of tumorigenicity 5 isoform 1 
ST5                   0.436   suppression of tumorigenicity 5 isoform 1 
ST5                   0.436   suppression of tumorigenicity 5 isoform 2 
DENND2C               0.413   DENN/MADD domain containing 2C 
DENND2A               0.391   DENN/MADD domain containing 2A 
DENND1A               0.132   DENN/MADD domain containing 1A isoform 2 
DENND1A               0.132   DENN/MADD domain containing 1A isoform 1 
DENND1B               0.123   DENN/MADD domain containing 1B isoform 1 
DENND1B               0.119   DENN/MADD domain containing 1B isoform 2 
DENND1C               0.114   DENN/MADD domain containing 1C 
DENND4A               0.071   DENN/MADD domain containing 4A isoform 1 
DENND4A               0.071   DENN/MADD domain containing 4A isoform 2 
DENND4C               0.058   DENN/MADD domain containing 4C 
DENND4B               0.054   DENN/MADD domain containing 4B 
SBF1                  0.053   SET binding factor 1 
DENND3                0.048   DENN/MADD domain containing 3 
SBF2                  0.048   SET binding factor 2 
DENND5B               0.044   DENN/MADD domain containing 5B 
DENND5A               0.043   RAB6 interacting protein 1 
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing protei...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
MADD                  0.028   MAP-kinase activating death domain-containing prote...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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