BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|209862785 anoctamin 2 [Homo sapiens] (998 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|209862785 anoctamin 2 [Homo sapiens] 2022 0.0 gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 1161 0.0 gi|218084958 anoctamin 4 [Homo sapiens] 681 0.0 gi|156766084 transmembrane protein 16C [Homo sapiens] 649 0.0 gi|218081589 anoctamin 5 isoform b [Homo sapiens] 623 e-178 gi|47106048 anoctamin 5 isoform a [Homo sapiens] 623 e-178 gi|218156303 anoctamin 6 isoform b [Homo sapiens] 561 e-160 gi|218156299 anoctamin 6 isoform a [Homo sapiens] 561 e-160 gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 548 e-156 gi|218156307 anoctamin 6 isoform c [Homo sapiens] 546 e-155 gi|218156305 anoctamin 6 isoform c [Homo sapiens] 546 e-155 gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 411 e-114 gi|94536803 transmembrane protein 16K [Homo sapiens] 139 1e-32 gi|55741655 anoctamin 8 [Homo sapiens] 102 2e-21 gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 92 2e-18 gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 84 7e-16 gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 78 5e-14 gi|10863913 solute carrier family 8 (sodium/calcium exchanger), ... 36 0.16 gi|163914373 solute carrier family 8 (sodium/calcium exchanger),... 36 0.16 gi|163914371 solute carrier family 8 (sodium/calcium exchanger),... 36 0.16 gi|163914369 solute carrier family 8 (sodium/calcium exchanger),... 36 0.16 gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 34 0.60 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 33 1.0 gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens] 33 1.0 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 33 1.0 gi|57163987 solute carrier family 8 member 2 [Homo sapiens] 33 1.0 gi|51479177 iroquois homeobox protein 1 [Homo sapiens] 33 1.3 gi|122939172 connexin 45 [Homo sapiens] 33 1.3 gi|69122473 connexin 45 [Homo sapiens] 33 1.3 gi|56549696 E1A binding protein p400 [Homo sapiens] 33 1.7 >gi|209862785 anoctamin 2 [Homo sapiens] Length = 998 Score = 2022 bits (5239), Expect = 0.0 Identities = 998/998 (100%), Positives = 998/998 (100%) Query: 1 MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGES 60 MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGES Sbjct: 1 MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGES 60 Query: 61 TRSSSVINNYLDANEPVSLEARLSRMHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLA 120 TRSSSVINNYLDANEPVSLEARLSRMHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLA Sbjct: 61 TRSSSVINNYLDANEPVSLEARLSRMHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLA 120 Query: 121 IVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENKSQGS 180 IVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENKSQGS Sbjct: 121 IVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENKSQGS 180 Query: 181 IFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHS 240 IFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHS Sbjct: 181 IFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHS 240 Query: 241 NNKMKNLSYPFSREKMYLYNIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGINSLIA 300 NNKMKNLSYPFSREKMYLYNIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGINSLIA Sbjct: 241 NNKMKNLSYPFSREKMYLYNIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGINSLIA 300 Query: 301 NNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFA 360 NNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFA Sbjct: 301 NNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFA 360 Query: 361 WLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSS 420 WLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSS Sbjct: 361 WLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSS 420 Query: 421 ACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEH 480 ACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEH Sbjct: 421 ACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEH 480 Query: 481 SRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFM 540 SRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFM Sbjct: 481 SRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFM 540 Query: 541 IALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAK 600 IALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAK Sbjct: 541 IALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAK 600 Query: 601 WLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRM 660 WLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRM Sbjct: 601 WLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRM 660 Query: 661 EECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSK 720 EECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSK Sbjct: 661 EECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSK 720 Query: 721 HPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKF 780 HPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKF Sbjct: 721 HPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKF 780 Query: 781 VTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLH 840 VTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLH Sbjct: 781 VTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLH 840 Query: 841 GFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSA 900 GFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSA Sbjct: 841 GFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSA 900 Query: 901 RLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPA 960 RLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPA Sbjct: 901 RLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPA 960 Query: 961 LRSPGGGDRSRSRAASSAPSGQSQLGSMMSSGSQHTNV 998 LRSPGGGDRSRSRAASSAPSGQSQLGSMMSSGSQHTNV Sbjct: 961 LRSPGGGDRSRSRAASSAPSGQSQLGSMMSSGSQHTNV 998 >gi|194306539 anoctamin 1, calcium activated chloride channel [Homo sapiens] Length = 986 Score = 1161 bits (3004), Expect = 0.0 Identities = 563/894 (62%), Positives = 701/894 (78%), Gaps = 22/894 (2%) Query: 86 MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHA--GGPGDIELG- 142 ++F D +RKVDY+L YH+++ + S + K+ H G ++ G Sbjct: 53 LYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGS 112 Query: 143 ---PLDALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFL 199 P+D E++++ +REE+E NL+EAGLELE+D + K G FV+IHAPW VL REAEFL Sbjct: 113 GEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFL 172 Query: 200 KIKVPTKKMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLY 259 K+K+PTKKMY I + KK ++ LQK++ +QP+V EH MK LSYPFSREK +L+ Sbjct: 173 KLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLF 232 Query: 260 NIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPE 319 ++ +KD+FFD+ TRS IV+EILKRT C++A +MGI SL+AN +Y AAYPLHDG+Y+ Sbjct: 233 DLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGEN 292 Query: 320 DDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIV 379 + NDRKLLY+EWARYGVFYK+QPIDL+RKYFGEKIGLYFAWLG+YT LIP+S++G+IV Sbjct: 293 VEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIV 352 Query: 380 FLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFF 439 FLYGCAT++E+IPS EMCDQ++ TMCPLCDK+C YW +SSAC TA+ASHLFDNPATVFF Sbjct: 353 FLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFF 412 Query: 440 SIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQ 499 S+FMALWA F+E+WKR QMRL Y WDLTG EEEEE ++H R EYE +V EK LK+ ++ Sbjct: 413 SVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESR 472 Query: 500 SAVQ------------KLETNTTECGDE-DDEDKLTWKDRFPGYLMNFASILFMIALTFS 546 + + K T G + D+ KLTW+DRFP YL N SI+FMIA+TF+ Sbjct: 473 NKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFA 532 Query: 547 IVFGVIVYRITTAAALSLNK--ATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTK 604 IV GVI+YRI+ AAAL++N + RSN+RVTVTATAVIINLVVI++LDE+YG +A+WLTK Sbjct: 533 IVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTK 592 Query: 605 IEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECA 664 IEVPKTE++FEERLI KAFLLKFVN+Y+PIFYVAFFKGRFVGRPG YVY+F +RMEECA Sbjct: 593 IEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECA 652 Query: 665 PGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQ 724 PGGCLMELCIQLSIIMLGKQLIQNN+FEIG+PK+KKL R LK + ++ K ++ Sbjct: 653 PGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQR 712 Query: 725 WDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784 +++DY+LEP+ GLTPEYMEMIIQFGFVTLFVASFPLAP+FALLNN+IE+RLDAKKFVTEL Sbjct: 713 YEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTEL 772 Query: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVN 844 RRP AVR KDIGIW++IL GIGK +VI NAFVI+ TSDFIPRLVY Y YS NGT+HGFVN Sbjct: 773 RRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVN 832 Query: 845 HTLSFFNVSQLKEGTQPENS-QFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLA 903 HTLS FNVS + GT P + EVQ CR+KDYREPPW+ N Y+ SK +W +L+ARLA Sbjct: 833 HTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLA 892 Query: 904 FVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMD 957 FVI+FQNLVMF+S VDW+IPDIP DIS QI KEK L+V+ F++EE +K +L++ Sbjct: 893 FVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLE 946 >gi|218084958 anoctamin 4 [Homo sapiens] Length = 920 Score = 681 bits (1757), Expect = 0.0 Identities = 357/829 (43%), Positives = 519/829 (62%), Gaps = 51/829 (6%) Query: 153 EQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVP-TKKMYEI 211 E+RE FE N+ GL++EK+ + IFV++HAPW+VL R AE + +++P +K+Y + Sbjct: 98 EKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYL 157 Query: 212 KAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNL------SYPFSREKMYLYNIQEKD 265 + + + L + + +L + PFS+++++ + I K+ Sbjct: 158 PRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKE 217 Query: 266 TFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPEDDM--- 322 TFF+NATRSRIVH IL+R N +G+N L+ N YEAA+PLH+G Y S Sbjct: 218 TFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHG 277 Query: 323 --NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVF 380 N R LLY+ WA +GV+YK+QP+DL+R+YFGEKIGLYFAWLG YT L P++ IG+ VF Sbjct: 278 AENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVF 337 Query: 381 LYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFS 440 LYG T++ S+E+C Q MCP+CDK C + LS +C A+ +HLFDN ATVFF+ Sbjct: 338 LYGVTTLDHSQVSKEVC-QATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFA 396 Query: 441 IFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQS 500 +FMA+WAT+FLE WKR + + Y WDL EEEEE RP++E K +K Sbjct: 397 VFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEI----RPQFEAKYSKKERMNPISG 452 Query: 501 AVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAA 560 + + T +C +++ + I FMI + + VFG+++YR+ T + Sbjct: 453 KPEPYQAFTDKCSR---------------LIVSASGIFFMICVVIAAVFGIVIYRVVTVS 497 Query: 561 ALSLNK--ATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERL 618 + K R+N +V T TAV IN +I++L+ +Y VA LT +E P+TE +E Sbjct: 498 TFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSF 557 Query: 619 ILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSI 678 LK FL +FVN S FY+AFF GRF G PG+Y+ + + +R+EEC P GCL++LC+Q+ I Sbjct: 558 TLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGI 617 Query: 679 IMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYT--G 736 IM+ KQ NN E+G P ++ + + K E G QW+ DY+L+P G Sbjct: 618 IMVLKQT-WNNFMELGYPLIQNWWTRRKVRQEHGPERKISFP---QWEKDYNLQPMNAYG 673 Query: 737 LTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIG 796 L EY+EMI+QFGF T+FVA+FPLAP+ ALLNN+IE+RLDA KFVT+ RRP A R KDIG Sbjct: 674 LFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIG 733 Query: 797 IWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSY--------SHNGTLHGFVNHTLS 848 IW+ IL GIG SVI+NAFVIAITSDFIPRLVY Y Y + + G+VN +LS Sbjct: 734 IWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLS 793 Query: 849 FFNVSQLKEGTQPEN--SQFD-QEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFV 905 F +S + ++PE+ S+F +++CR++DYR+PP + PY ++ Q+W +L+ARLAF+ Sbjct: 794 VFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFI 853 Query: 906 IIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954 I+F++LV + L+ ++IPD+P D+ D++++EK L+ + + E E+L+ Sbjct: 854 IVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQ 902 >gi|156766084 transmembrane protein 16C [Homo sapiens] Length = 981 Score = 649 bits (1674), Expect = 0.0 Identities = 356/826 (43%), Positives = 499/826 (60%), Gaps = 61/826 (7%) Query: 153 EQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVP-TKKMYEI 211 ++R FE NL GL LEK+ S +F++IH PW L + AE L I++P KK Y Sbjct: 178 DKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYT 237 Query: 212 KAGGSIAKKFSAALQKLSSHL--QPRVPEHSN----NKMKNLSYPFSREKMYLYNIQEKD 265 + +++ + + P V + S + + PFSR +++ + I KD Sbjct: 238 DGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKD 297 Query: 266 TFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPED----- 320 TFF NATRSRIV+ +L+RT + +GI LI N Y AA+P H+G Y S + Sbjct: 298 TFFSNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHG 357 Query: 321 DMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVF 380 N+R LLY+ WAR+G++YK QP+DLIR YFGEKIGLYFAWLG YT LIP++++G+ VF Sbjct: 358 PQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVF 417 Query: 381 LYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFS 440 YG T+ S+E+C F MCPLCDK+C L+ +C A+ ++LFDN TVFF+ Sbjct: 418 FYGLFTMNNSQVSQEICKATEVF-MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFA 476 Query: 441 IFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQS 500 IFMA+WAT+FLE WKR + L Y WDL EEEEE RP++E K Sbjct: 477 IFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETL----RPQFEAKY----------- 521 Query: 501 AVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAA 560 K+E G + + D+ L++ + I FMI+L + VFGV+VYR+ Sbjct: 522 --YKMEIVNPITGKPEPHQPSS--DKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVME 577 Query: 561 ALSLNKAT--RSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERL 618 + K + + +A AV IN ++I++L+ Y +A LT +E P+TE +E Sbjct: 578 QFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSF 637 Query: 619 ILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSI 678 LK FL +FVN S IFY+AFF GRFVG PG Y +FD +R+EEC P GCL++LC+Q+ + Sbjct: 638 ALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGV 697 Query: 679 IMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYT--G 736 IM KQ I NN E+G P ++ + + K + H QW+ D++L+P G Sbjct: 698 IMFLKQ-IWNNFMELGYPLIQNWWSRHKIKR------GIHDASIPQWENDWNLQPMNLHG 750 Query: 737 LTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIG 796 L EY+EM++QFGF T+FVA+FPLAP+ ALLNN+IE+RLDA KFVT+ RRP R DIG Sbjct: 751 LMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIG 810 Query: 797 IWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS--------HNGTLHGFVNHTLS 848 IW IL GIG +VI+NAFVIAITSD+IPR VY+Y Y L G+VN++LS Sbjct: 811 IWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLS 870 Query: 849 FFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIF 908 FF++S+L G + +CR++DYR PPW+ PYEF+ QYW IL+ARLAF+I+F Sbjct: 871 FFDLSELGMG----------KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVF 920 Query: 909 QNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954 ++LV + + ++IPD+P + D+I++EK L+ + + E E L+ Sbjct: 921 EHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQ 966 >gi|218081589 anoctamin 5 isoform b [Homo sapiens] Length = 912 Score = 623 bits (1606), Expect = e-178 Identities = 345/828 (41%), Positives = 499/828 (60%), Gaps = 59/828 (7%) Query: 149 EERKEQREEFEHNLMEAGLELE-KDLENKSQG-SIFVRIHAPWQVLAREAEFLKIKVPTK 206 E + E+R+EFE NL + GLELE +D + G + FV+IHAPW+VL AE L IK+P K Sbjct: 94 ELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIK 153 Query: 207 KMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQEKDT 266 + +I + +L ++ PE+ + FSR + L+ I+++ T Sbjct: 154 ES-DIPRPKHTPISYVLGPVRLPLSVKYPHPEY-------FTAQFSRHRQELFLIEDQAT 205 Query: 267 FFDNATRSRIVHEILKRT--ACSRANNTMGINSLIANNIYEAAYPLHDGEY---DSPEDD 321 FF +++R+RIV+ IL R GI L+ +N Y +AYPLHDG+Y P + Sbjct: 206 FFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNP 265 Query: 322 MNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFL 381 N+R L+Q WAR+ FYK QP+DLI+ Y+GEKIG+YF +LG YT L ++V+G+ F+ Sbjct: 266 TNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFI 325 Query: 382 YGCATIEEDIPSREMCDQQ--NAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFF 439 YG ++E + S E+CD + MCPLCD+ CDYW L+S C ++ SHLFDN +TVFF Sbjct: 326 YGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFF 385 Query: 440 SIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQ 499 +IFM +W T+FLE WK+ Q RL Y WDL EEE+++ Q RPE+E M K Sbjct: 386 AIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQ--LRPEFEA-----MCKHRKL 438 Query: 500 SAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRIT-- 557 +AV K + E + R P Y ++ A++ ++L + + VIVYR++ Sbjct: 439 NAVTK-----------EMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVF 487 Query: 558 -TAAALSLNKATRSNVR------VTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKT 610 T A+ + A+ V+ +T + T +N +VILIL+ Y ++ W+TK+E+P+T Sbjct: 488 ATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRT 547 Query: 611 EQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLM 670 Q +E L LK FL +FVN YS FYVAFFKG+FVG PG Y Y+F+ +R EEC PGGCL+ Sbjct: 548 YQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLI 607 Query: 671 ELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYS 730 EL QL+IIM GKQ+ NI E P +R+ K T + K +W+ D+ Sbjct: 608 ELTTQLTIIMTGKQIF-GNIKEAIYPLALNWWRRRKARTNS-------EKLYSRWEQDHD 659 Query: 731 LEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPD 788 LE + GL EY+E + QFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ RR Sbjct: 660 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 719 Query: 789 AVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGT--LHGFVNHT 846 A + IG+W DIL G+ SV +NAF++A TSD IPRLVY Y+YS N T + G+VN++ Sbjct: 720 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 779 Query: 847 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVI 906 LS F ++ T P ++ CR++DYR PP N Y + Q+W +L+A++ F+I Sbjct: 780 LSVFLIADFPNHTAPSEK---RDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFII 836 Query: 907 IFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954 + +++V + L+ WMIPD+P D+ ++IK+EK + + E KLK Sbjct: 837 VMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLK 884 >gi|47106048 anoctamin 5 isoform a [Homo sapiens] Length = 913 Score = 623 bits (1606), Expect = e-178 Identities = 345/828 (41%), Positives = 499/828 (60%), Gaps = 59/828 (7%) Query: 149 EERKEQREEFEHNLMEAGLELE-KDLENKSQG-SIFVRIHAPWQVLAREAEFLKIKVPTK 206 E + E+R+EFE NL + GLELE +D + G + FV+IHAPW+VL AE L IK+P K Sbjct: 95 ELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIK 154 Query: 207 KMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQEKDT 266 + +I + +L ++ PE+ + FSR + L+ I+++ T Sbjct: 155 ES-DIPRPKHTPISYVLGPVRLPLSVKYPHPEY-------FTAQFSRHRQELFLIEDQAT 206 Query: 267 FFDNATRSRIVHEILKRT--ACSRANNTMGINSLIANNIYEAAYPLHDGEY---DSPEDD 321 FF +++R+RIV+ IL R GI L+ +N Y +AYPLHDG+Y P + Sbjct: 207 FFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNP 266 Query: 322 MNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFL 381 N+R L+Q WAR+ FYK QP+DLI+ Y+GEKIG+YF +LG YT L ++V+G+ F+ Sbjct: 267 TNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFI 326 Query: 382 YGCATIEEDIPSREMCDQQ--NAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFF 439 YG ++E + S E+CD + MCPLCD+ CDYW L+S C ++ SHLFDN +TVFF Sbjct: 327 YGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFF 386 Query: 440 SIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQ 499 +IFM +W T+FLE WK+ Q RL Y WDL EEE+++ Q RPE+E M K Sbjct: 387 AIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQ--LRPEFEA-----MCKHRKL 439 Query: 500 SAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRIT-- 557 +AV K + E + R P Y ++ A++ ++L + + VIVYR++ Sbjct: 440 NAVTK-----------EMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVF 488 Query: 558 -TAAALSLNKATRSNVR------VTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKT 610 T A+ + A+ V+ +T + T +N +VILIL+ Y ++ W+TK+E+P+T Sbjct: 489 ATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRT 548 Query: 611 EQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLM 670 Q +E L LK FL +FVN YS FYVAFFKG+FVG PG Y Y+F+ +R EEC PGGCL+ Sbjct: 549 YQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLI 608 Query: 671 ELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYS 730 EL QL+IIM GKQ+ NI E P +R+ K T + K +W+ D+ Sbjct: 609 ELTTQLTIIMTGKQIF-GNIKEAIYPLALNWWRRRKARTNS-------EKLYSRWEQDHD 660 Query: 731 LEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPD 788 LE + GL EY+E + QFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ RR Sbjct: 661 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 720 Query: 789 AVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGT--LHGFVNHT 846 A + IG+W DIL G+ SV +NAF++A TSD IPRLVY Y+YS N T + G+VN++ Sbjct: 721 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 780 Query: 847 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVI 906 LS F ++ T P ++ CR++DYR PP N Y + Q+W +L+A++ F+I Sbjct: 781 LSVFLIADFPNHTAPSEK---RDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFII 837 Query: 907 IFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954 + +++V + L+ WMIPD+P D+ ++IK+EK + + E KLK Sbjct: 838 VMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLK 885 >gi|218156303 anoctamin 6 isoform b [Homo sapiens] Length = 892 Score = 561 bits (1447), Expect = e-160 Identities = 331/895 (36%), Positives = 488/895 (54%), Gaps = 98/895 (10%) Query: 86 MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLD 145 + F+D QR++D+VL Y R ET K+ Sbjct: 42 LFFNDGQRRIDFVLVYEDESRK------------------ETNKK--------------- 68 Query: 146 ALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPT 205 E+++ +R+ +E NL+ GL+LE +FV++HAPW+VL AE + IK+P Sbjct: 69 GTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPL 128 Query: 206 KK--MYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQE 263 K + + F+ L S ++P + + + PF + +M + I + Sbjct: 129 KPNDLKNRSSAFGTLNWFTKVLSVDESIIKP--------EQEFFTAPFEKNRMNDFYIVD 180 Query: 264 KDTFFDNATRSRIVHEILKRTACSRANNT--MGINSLIANNIYEAAYPLHDGEYDSPEDD 321 +D FF+ ATRSRIV+ IL R NN GIN L+ + IY+AA+PLHD ++ +D Sbjct: 181 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 240 Query: 322 M---NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVI 378 N+R LLY+EWA YK QP+DLIRKY+GEKIG+YFAWLG YT L+ ++V+GV Sbjct: 241 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 300 Query: 379 VFLYGCATIEEDIPSREMC--DQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPAT 436 FLYG + S+E+C D MCP CD+ C +W L+ C +++ +FD+ T Sbjct: 301 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 360 Query: 437 VFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKE 496 + F++FM +W T+FLE WKR Q L Y WD +++EE+ +RPEYE + ++ E Sbjct: 361 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQ-----ARPEYEARCTHVVINE 415 Query: 497 SNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRI 556 Q E++ T + + +++ F I L + V G+IVYR+ Sbjct: 416 ITQ---------------EEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRL 460 Query: 557 TTAAALSLNKATRSN----------VRVTVTATAVIINLVVILILDEIYGAVAKWLTKIE 606 + S N + + TA II+ ++I+IL+ IY VA +T E Sbjct: 461 SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFE 520 Query: 607 VPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPG 666 +P+T+ +E L +K FL +FVN YS FY+AFFKG+FVG PG VY YR EEC PG Sbjct: 521 LPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPG 580 Query: 667 GCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWD 726 GCL+EL QL+IIM GK I NNI E+ +P + L + S K +W+ Sbjct: 581 GCLLELTTQLTIIMGGKA-IWNNIQEVLLPWIMNLIGRF-------HRVSGSEKITPRWE 632 Query: 727 LDYSLEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784 DY L+P GL EY+EMIIQFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ Sbjct: 633 QDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQF 692 Query: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS------HNG- 837 RR + +DIG W I+ GI +V++NA +IA TSD IPRLVY +S+S H Sbjct: 693 RRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY 752 Query: 838 TLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFI 897 T+ G++N+TLS F V+ K ++ CR++D+R PP P Y+ + YW + Sbjct: 753 TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHV 812 Query: 898 LSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEK 952 ++A+LAF+I+ ++++ + + + IPD+ +I++EK L L E H K Sbjct: 813 IAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREK-YLTQKLLHENHLK 866 >gi|218156299 anoctamin 6 isoform a [Homo sapiens] Length = 910 Score = 561 bits (1447), Expect = e-160 Identities = 331/895 (36%), Positives = 488/895 (54%), Gaps = 98/895 (10%) Query: 86 MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLD 145 + F+D QR++D+VL Y R ET K+ Sbjct: 60 LFFNDGQRRIDFVLVYEDESRK------------------ETNKK--------------- 86 Query: 146 ALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPT 205 E+++ +R+ +E NL+ GL+LE +FV++HAPW+VL AE + IK+P Sbjct: 87 GTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPL 146 Query: 206 KK--MYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQE 263 K + + F+ L S ++P + + + PF + +M + I + Sbjct: 147 KPNDLKNRSSAFGTLNWFTKVLSVDESIIKP--------EQEFFTAPFEKNRMNDFYIVD 198 Query: 264 KDTFFDNATRSRIVHEILKRTACSRANNT--MGINSLIANNIYEAAYPLHDGEYDSPEDD 321 +D FF+ ATRSRIV+ IL R NN GIN L+ + IY+AA+PLHD ++ +D Sbjct: 199 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 258 Query: 322 M---NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVI 378 N+R LLY+EWA YK QP+DLIRKY+GEKIG+YFAWLG YT L+ ++V+GV Sbjct: 259 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 318 Query: 379 VFLYGCATIEEDIPSREMC--DQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPAT 436 FLYG + S+E+C D MCP CD+ C +W L+ C +++ +FD+ T Sbjct: 319 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 378 Query: 437 VFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKE 496 + F++FM +W T+FLE WKR Q L Y WD +++EE+ +RPEYE + ++ E Sbjct: 379 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQ-----ARPEYEARCTHVVINE 433 Query: 497 SNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRI 556 Q E++ T + + +++ F I L + V G+IVYR+ Sbjct: 434 ITQ---------------EEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRL 478 Query: 557 TTAAALSLNKATRSN----------VRVTVTATAVIINLVVILILDEIYGAVAKWLTKIE 606 + S N + + TA II+ ++I+IL+ IY VA +T E Sbjct: 479 SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFE 538 Query: 607 VPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPG 666 +P+T+ +E L +K FL +FVN YS FY+AFFKG+FVG PG VY YR EEC PG Sbjct: 539 LPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPG 598 Query: 667 GCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWD 726 GCL+EL QL+IIM GK I NNI E+ +P + L + S K +W+ Sbjct: 599 GCLLELTTQLTIIMGGKA-IWNNIQEVLLPWIMNLIGRF-------HRVSGSEKITPRWE 650 Query: 727 LDYSLEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784 DY L+P GL EY+EMIIQFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ Sbjct: 651 QDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQF 710 Query: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS------HNG- 837 RR + +DIG W I+ GI +V++NA +IA TSD IPRLVY +S+S H Sbjct: 711 RRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY 770 Query: 838 TLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFI 897 T+ G++N+TLS F V+ K ++ CR++D+R PP P Y+ + YW + Sbjct: 771 TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHV 830 Query: 898 LSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEK 952 ++A+LAF+I+ ++++ + + + IPD+ +I++EK L L E H K Sbjct: 831 IAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREK-YLTQKLLHENHLK 884 >gi|145207958 transmembrane protein 16G isoform NGEP long [Homo sapiens] Length = 933 Score = 548 bits (1412), Expect = e-156 Identities = 314/793 (39%), Positives = 472/793 (59%), Gaps = 57/793 (7%) Query: 155 REEFEHNLMEAGLELEK-DLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKA 213 RE F NL AGL +++ D+++ + + + A W VL AE L++K+P +++ + Sbjct: 141 RETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQAS 200 Query: 214 GGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLY-NIQEKDTFFDNAT 272 S + + + P VP + S F K+ + +DTFF + Sbjct: 201 NWSAGLLAWLGIPNVLLEVVPDVPP------EYYSCRFRVNKLPRFLGSDNQDTFFTSTK 254 Query: 273 RSRIVHEILKRTACSRAN-NTMGINSLIANNIYEAAYPLHDGEYDSPEDD-----MNDRK 326 R +I+ EIL +T N +GI+ L+A + AA+PLHDG + +P + +N R+ Sbjct: 255 RHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQ 314 Query: 327 LLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCAT 386 +L+Q WAR+G + K+QP+D +R+YFGEK+ LYFAWLG YT +L+P++V+G +VFL GC Sbjct: 315 VLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFL 374 Query: 387 IEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFSIFMALW 446 + DIP++E+C +++F MCPLC C +W LSSAC AQA LFD+ TVFFS+FMALW Sbjct: 375 VFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALW 433 Query: 447 ATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQSAVQKLE 506 A + LE WKR L Y WD + E+ EER RP++ SA Sbjct: 434 AVLLLEYWKRKSATLAYRWDCSDYEDTEERP----RPQFAA------------SAPMTAP 477 Query: 507 TNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNK 566 T +DE + R L I+ M+A+ + +I+YR A +S + Sbjct: 478 NPITG----EDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSG 533 Query: 567 ATRSNVRVTVTA--TAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFL 624 T + A T ++NLV ILIL +IY ++A LT+ E+ +T+ FE+ LK F+ Sbjct: 534 NTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFI 593 Query: 625 LKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQ 684 +FVN YS Y+AFFKGRFVG PG+Y +F G R EECA GGCL+EL +L +IM+GKQ Sbjct: 594 FQFVNFYSSPVYIAFFKGRFVGYPGNYHTLF-GVRNEECAAGGCLIELAQELLVIMVGKQ 652 Query: 685 LIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEM 744 +I NN+ E+ +PKLK ++K + ++ + ++ W+ DY L P GL EY+EM Sbjct: 653 VI-NNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEM 711 Query: 745 IIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSG 804 ++QFGFVT+FVA+ PLAP+FALLNN +E+RLDA+KFV E RRP A R +DIGIWF IL+G Sbjct: 712 VLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAG 771 Query: 805 IGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENS 864 + +VISNAF++A +SDF+PR Y+++ +H+ L GF+N TL+ + +S Sbjct: 772 LTHLAVISNAFLLAFSSDFLPRAYYRWTRAHD--LRGFLNFTLA-----------RAPSS 818 Query: 865 QFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIP 924 + CR++ +R+ + +S+ YW +L+ RLAFVI+F+++V + L+D ++P Sbjct: 819 FAAAHNRTCRYRAFRD-----DDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873 Query: 925 DIPTDISDQIKKE 937 DIP + ++K+E Sbjct: 874 DIPESVEIKVKRE 886 >gi|218156307 anoctamin 6 isoform c [Homo sapiens] Length = 929 Score = 546 bits (1406), Expect = e-155 Identities = 321/856 (37%), Positives = 469/856 (54%), Gaps = 97/856 (11%) Query: 86 MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLD 145 + F+D QR++D+VL Y R ET K+ Sbjct: 60 LFFNDGQRRIDFVLVYEDESRK------------------ETNKK--------------- 86 Query: 146 ALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPT 205 E+++ +R+ +E NL+ GL+LE +FV++HAPW+VL AE + IK+P Sbjct: 87 GTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPL 146 Query: 206 KK--MYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQE 263 K + + F+ L S ++P + + + PF + +M + I + Sbjct: 147 KPNDLKNRSSAFGTLNWFTKVLSVDESIIKP--------EQEFFTAPFEKNRMNDFYIVD 198 Query: 264 KDTFFDNATRSRIVHEILKRTACSRANNT--MGINSLIANNIYEAAYPLHDGEYDSPEDD 321 +D FF+ ATRSRIV+ IL R NN GIN L+ + IY+AA+PLHD ++ +D Sbjct: 199 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 258 Query: 322 M---NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVI 378 N+R LLY+EWA YK QP+DLIRKY+GEKIG+YFAWLG YT L+ ++V+GV Sbjct: 259 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 318 Query: 379 VFLYGCATIEEDIPSREMC--DQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPAT 436 FLYG + S+E+C D MCP CD+ C +W L+ C +++ +FD+ T Sbjct: 319 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 378 Query: 437 VFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKE 496 + F++FM +W T+FLE WKR Q L Y WD +++EE+ +RPEYE + ++ E Sbjct: 379 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQ-----ARPEYEARCTHVVINE 433 Query: 497 SNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRI 556 Q E++ T + + +++ F I L + V G+IVYR+ Sbjct: 434 ITQ---------------EEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRL 478 Query: 557 TTAAALSLNKATRSN----------VRVTVTATAVIINLVVILILDEIYGAVAKWLTKIE 606 + S N + + TA II+ ++I+IL+ IY VA +T E Sbjct: 479 SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFE 538 Query: 607 VPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPG 666 +P+T+ +E L +K FL +FVN YS FY+AFFKG+FVG PG VY YR EEC PG Sbjct: 539 LPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPG 598 Query: 667 GCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWD 726 GCL+EL QL+IIM GK I NNI E+ +P + L + S K +W+ Sbjct: 599 GCLLELTTQLTIIMGGKA-IWNNIQEVLLPWIMNLIGRF-------HRVSGSEKITPRWE 650 Query: 727 LDYSLEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784 DY L+P GL EY+EMIIQFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ Sbjct: 651 QDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQF 710 Query: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS------HNG- 837 RR + +DIG W I+ GI +V++NA +IA TSD IPRLVY +S+S H Sbjct: 711 RRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY 770 Query: 838 TLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFI 897 T+ G++N+TLS F V+ K ++ CR++D+R PP P Y+ + YW + Sbjct: 771 TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHV 830 Query: 898 LSARLAFVIIFQNLVM 913 ++A+LAF+I+ + L + Sbjct: 831 IAAKLAFIIVMEYLAL 846 >gi|218156305 anoctamin 6 isoform c [Homo sapiens] Length = 929 Score = 546 bits (1406), Expect = e-155 Identities = 321/856 (37%), Positives = 469/856 (54%), Gaps = 97/856 (11%) Query: 86 MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLD 145 + F+D QR++D+VL Y R ET K+ Sbjct: 60 LFFNDGQRRIDFVLVYEDESRK------------------ETNKK--------------- 86 Query: 146 ALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPT 205 E+++ +R+ +E NL+ GL+LE +FV++HAPW+VL AE + IK+P Sbjct: 87 GTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPL 146 Query: 206 KK--MYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQE 263 K + + F+ L S ++P + + + PF + +M + I + Sbjct: 147 KPNDLKNRSSAFGTLNWFTKVLSVDESIIKP--------EQEFFTAPFEKNRMNDFYIVD 198 Query: 264 KDTFFDNATRSRIVHEILKRTACSRANNT--MGINSLIANNIYEAAYPLHDGEYDSPEDD 321 +D FF+ ATRSRIV+ IL R NN GIN L+ + IY+AA+PLHD ++ +D Sbjct: 199 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 258 Query: 322 M---NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVI 378 N+R LLY+EWA YK QP+DLIRKY+GEKIG+YFAWLG YT L+ ++V+GV Sbjct: 259 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 318 Query: 379 VFLYGCATIEEDIPSREMC--DQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPAT 436 FLYG + S+E+C D MCP CD+ C +W L+ C +++ +FD+ T Sbjct: 319 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 378 Query: 437 VFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKE 496 + F++FM +W T+FLE WKR Q L Y WD +++EE+ +RPEYE + ++ E Sbjct: 379 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQ-----ARPEYEARCTHVVINE 433 Query: 497 SNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRI 556 Q E++ T + + +++ F I L + V G+IVYR+ Sbjct: 434 ITQ---------------EEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRL 478 Query: 557 TTAAALSLNKATRSN----------VRVTVTATAVIINLVVILILDEIYGAVAKWLTKIE 606 + S N + + TA II+ ++I+IL+ IY VA +T E Sbjct: 479 SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFE 538 Query: 607 VPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPG 666 +P+T+ +E L +K FL +FVN YS FY+AFFKG+FVG PG VY YR EEC PG Sbjct: 539 LPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPG 598 Query: 667 GCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWD 726 GCL+EL QL+IIM GK I NNI E+ +P + L + S K +W+ Sbjct: 599 GCLLELTTQLTIIMGGKA-IWNNIQEVLLPWIMNLIGRF-------HRVSGSEKITPRWE 650 Query: 727 LDYSLEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784 DY L+P GL EY+EMIIQFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ Sbjct: 651 QDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQF 710 Query: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS------HNG- 837 RR + +DIG W I+ GI +V++NA +IA TSD IPRLVY +S+S H Sbjct: 711 RRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY 770 Query: 838 TLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFI 897 T+ G++N+TLS F V+ K ++ CR++D+R PP P Y+ + YW + Sbjct: 771 TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHV 830 Query: 898 LSARLAFVIIFQNLVM 913 ++A+LAF+I+ + L + Sbjct: 831 IAAKLAFIIVMEYLAL 846 >gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] Length = 782 Score = 411 bits (1057), Expect = e-114 Identities = 252/683 (36%), Positives = 372/683 (54%), Gaps = 79/683 (11%) Query: 273 RSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEW 332 R RIV+ ++ S L+ + ++EA +PLH GE L + W Sbjct: 119 RIRIVNFVVMNNKTSAGET---FEDLMKDGVFEARFPLHKGE-----------GRLKKTW 164 Query: 333 ARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIP 392 AR+ ++ QP+D IR YFGEK+ LYF WLG YT L+P+++ G++VFL G + E Sbjct: 165 ARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQI 224 Query: 393 SREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFSIFMALWATMFLE 452 S+E+C+ + MCPL D S Y LS C A+ +HLFDN TV F+IFMALWAT+FLE Sbjct: 225 SKEICEAHDIL-MCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLE 283 Query: 453 NWKRLQMRLGYFWDLTGIEEEEERA--QEHSRPEYETKVREKMLKESNQSAVQKLETNTT 510 WKR + R+ WDL +EE+E Q + P+Y+ + + S V Sbjct: 284 IWKRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILV-------- 335 Query: 511 ECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRS 570 LT L MI L + ++VYR+ +A S + Sbjct: 336 ----------LT---------------LLMICLMIGMAHVLVVYRVLASALFSSSAVPFL 370 Query: 571 NVRVT--VTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFV 628 +VT V T +++ V I+I+ +I VA L E+P+T E R ++ F L+F Sbjct: 371 EEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFF 430 Query: 629 NAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQN 688 +S + Y+AF GR G PG + +++EEC GC+M+L +Q++IIM KQ + N Sbjct: 431 THFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSN 490 Query: 689 NIFEIGVPKLKKLFRKLKDETEAGETDSAH-SKHPE--QWDLDYSLEPYT--GLTPEYME 743 + E VP + R L+ ++S H + PE W +Y L P L E+ME Sbjct: 491 CV-EYLVPWVTHKCRSLR------ASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFME 543 Query: 744 MIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILS 803 M+IQ+GF T+FVA+FPLAP+ AL +N++E+RLDA K V RR + KDIG W +L Sbjct: 544 MMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLE 603 Query: 804 GIGKFSVISNAFVIAITSDFIPRLVYQYSYS-----HNGT---LHGFVNHTLSFFNVSQL 855 IG +VI+N VIA TS+FIPR+VY+Y YS N T L G+VNH+LS F+ Sbjct: 604 TIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHT--- 660 Query: 856 KEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFL 915 K+ P+ + + V CR++DYR PP Y FS+Q+WF+L+ RLAFVI+F+++ + + Sbjct: 661 KDFQDPDGIEGSENVTLCRYRDYRNPP----DYNFSEQFWFLLAIRLAFVILFEHVALCI 716 Query: 916 SVLVDWMIPDIPTDISDQIKKEK 938 ++ W +PDIP + +++ + K Sbjct: 717 KLIAAWFVPDIPQSVKNKVLEVK 739 >gi|94536803 transmembrane protein 16K [Homo sapiens] Length = 660 Score = 139 bits (350), Expect = 1e-32 Identities = 132/529 (24%), Positives = 219/529 (41%), Gaps = 112/529 (21%) Query: 295 INSLIANNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEW-ARYGVFYKFQPIDLIRKYFGE 353 + L+ + I +PLHD E K L W R+ + K+QPID IR YFGE Sbjct: 158 LRRLLTSGIVIQVFPLHDSEA---------LKKLEDTWYTRFAL--KYQPIDSIRGYFGE 206 Query: 354 KIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSC 413 I LYF +L +T LIP +VIG+ +L+ Sbjct: 207 TIALYFGFLEYFTFALIPMAVIGLPYYLF------------------------------- 235 Query: 414 DYWNLSSACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEE 473 W D V F+ F +W+T+ LE WKR + Y W ++ Sbjct: 236 -VWE--------------DYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMK-- 278 Query: 474 EERAQEHSRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMN 533 R E RP + + + + ++K + YL+ Sbjct: 279 --RKFEEPRPGFHGVLGINSITGKEEPLYP------------------SYKRQLRIYLV- 317 Query: 534 FASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDE 593 S+ F+ + ++ +++Y AL L++ + S + II +VI I++ Sbjct: 318 --SLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNR 375 Query: 594 IYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVY 653 +Y A++LT E + E ++ LILK + F+N ++ +FY+AF Sbjct: 376 LYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAFVLKD---------- 425 Query: 654 VFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKL--KKLFRKLKDETEA 711 M+L Q +L I N I E +P +K ++K + +A Sbjct: 426 ----------------MKLLRQSLATLLITSQILNQIMESFLPYWLQRKHGVRVKRKVQA 469 Query: 712 GETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVI 771 + D + + EQ L+ + Y G +Y+E+ +QFG+V+LF +PLA FA+LNN Sbjct: 470 LKADIDATLY-EQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFT 528 Query: 772 EVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAIT 820 EV DA K +RP + + +IG+W + SV++N +I ++ Sbjct: 529 EVNSDALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMS 577 >gi|55741655 anoctamin 8 [Homo sapiens] Length = 1232 Score = 102 bits (253), Expect = 2e-21 Identities = 94/400 (23%), Positives = 158/400 (39%), Gaps = 92/400 (23%) Query: 251 FSREKMYLY-NIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGIN---------SLIA 300 FS E+ ++Y N++ + FF + R I+ L+ + + L A Sbjct: 142 FSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAA 201 Query: 301 NNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFA 360 I + +P+H E + +R L + W + + QP+D I YFG KI +YFA Sbjct: 202 RGIIQQVFPVH-------EQRILNR--LMKSWVQ--AVCENQPLDDICDYFGVKIAMYFA 250 Query: 361 WLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSS 420 WLG YTS ++ +V G +++ + E D SR D SC Sbjct: 251 WLGFYTSAMVYPAVFGSVLYTF----TEADQTSR---------------DVSC------- 284 Query: 421 ACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEH 480 V F++F +W+T+FLE WKR L Y W G + A E Sbjct: 285 ----------------VVFALFNVIWSTLFLEEWKRRGAELAYKW---GTLDSPGEAVEE 325 Query: 481 SRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFM 540 RP++ R + + + WK L++ L Sbjct: 326 PRPQFRGVRRISPITRAEEFYYP------------------PWKRLLFQLLVSLPLCLAC 367 Query: 541 IALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAK 600 + F ++ G + + L + R +V + +++ + E Y +A Sbjct: 368 LVCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLA--------LLVSVSAEGYKKLAI 419 Query: 601 WLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFF 640 WL +E + E +E+ LI+K L +FVN+Y +FY+ F+ Sbjct: 420 WLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFY 459 Score = 83.6 bits (205), Expect = 9e-16 Identities = 39/103 (37%), Positives = 63/103 (61%) Query: 715 DSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVR 774 + HS Q +L+ ++ Y +Y EM +QFG+V LF ++FPLA + AL+NN+IE+R Sbjct: 722 EEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIR 781 Query: 775 LDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVI 817 DA K T L+RP R + IG W ++ +G +++ N ++I Sbjct: 782 SDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824 >gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] Length = 719 Score = 92.0 bits (227), Expect = 2e-18 Identities = 127/512 (24%), Positives = 203/512 (39%), Gaps = 118/512 (23%) Query: 428 SHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYET 487 S LFD+P TVFFSIFM+ W + L + WD + +++E A S P + Sbjct: 256 SCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQE--AMPSSAPHHWD 313 Query: 488 KVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSI 547 +Q + + +C D D+++ + FA++ + +T + Sbjct: 314 -----CSDFQDQEVMPSSALHHWDCSDFQDQEECPH--------LQFAALA--LQMTQNP 358 Query: 548 VFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEV 607 V G+ + LS S+ + V+I LV ++I I ++A + T V Sbjct: 359 VTGLKEPYFQPHSCLS--HLLTSSAAILTVLCVVMIFLVSVIIYHGII-SIAMFHTGNSV 415 Query: 608 PKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGG 667 T+ +A + ++F +F+ + + G +C PGG Sbjct: 416 LMTQAN--------VLWGNGGDASMKMPSLSFSVCQFL-----FFSLLHGILQRQCGPGG 462 Query: 668 CLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQW-D 726 C +++ QL IIM+GKQL+ H E++ Sbjct: 463 CHIQVTQQLIIIMVGKQLLN---------------------------------HMEEFVG 489 Query: 727 LDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRR 786 L P T PE +QFGF+T+FV +F LAP+F LLNN +E+ LDA KF+ + +R Sbjct: 490 LGGGPGPDTPCLPE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQR 544 Query: 787 PDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHT 846 P A R G S +I ++ RL Y NG Sbjct: 545 PMAGRGWTSG---------SDCSCWRPCELILPRTNARSRL----GYWLNGQ-------- 583 Query: 847 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNP-YEFSKQ--------YWFI 897 Q+ + N+ F E+ REP P P Y+ S+ YW + Sbjct: 584 ------GQILGRRRGGNAGFGVEI--------REPLQTPQPRYKASRDVGVNLALFYWKL 629 Query: 898 LS--ARLAFVIIFQNLVMFLSVLVDWMIPDIP 927 L+ L F+I F+N+V F D ++PD+P Sbjct: 630 LAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661 Score = 40.8 bits (94), Expect = 0.006 Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 9/70 (12%) Query: 277 VHEILKRTACSRANNT-MGINSLIANNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARY 335 V EIL RT + +T MGI L+ ++E Y P D+N +LLY WA + Sbjct: 188 VAEILDRTISRKKKHTEMGIAHLLG--LFELP------GYQVPGSDLNSCQLLYPYWACW 239 Query: 336 GVFYKFQPID 345 G ++K+QP+D Sbjct: 240 GYWHKYQPLD 249 >gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] Length = 723 Score = 84.0 bits (206), Expect = 7e-16 Identities = 124/510 (24%), Positives = 199/510 (39%), Gaps = 118/510 (23%) Query: 430 LFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKV 489 L D TVFFSIFM+ W + L + WD + +++E A S P + Sbjct: 262 LGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQE--AMPSSAPHHWD-- 317 Query: 490 REKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVF 549 +Q + + +C D D+++ + FA++ + +T + V Sbjct: 318 ---CSDFQDQEVMPSSALHHWDCSDFQDQEECPH--------LQFAALA--LQMTQNPVT 364 Query: 550 GVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPK 609 G+ + LS S+ + V+I LV ++I I ++A + T V Sbjct: 365 GLKEPYFQPHSCLS--HLLTSSAAILTVLCVVMIFLVSVIIYHGII-SIAMFHTGNSVLM 421 Query: 610 TEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCL 669 T+ +A + ++F +F+ + + G +C PGGC Sbjct: 422 TQAN--------VLWGNGGDASMKMPSLSFSVCQFL-----FFSLLHGILQRQCGPGGCH 468 Query: 670 MELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQW-DLD 728 +++ QL IIM+GKQL+ H E++ L Sbjct: 469 IQVTQQLIIIMVGKQLLN---------------------------------HMEEFVGLG 495 Query: 729 YSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPD 788 P T PE +QFGF+T+FV +F LAP+F LLNN +E+ LDA KF+ + +RP Sbjct: 496 GGPGPDTPCLPE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPM 550 Query: 789 AVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLS 848 A R G S +I ++ RL Y NG Sbjct: 551 AGRGWTSG---------SDCSCWRPCELILPRTNARSRL----GYWLNGQ---------- 587 Query: 849 FFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNP-YEFSKQ--------YWFILS 899 Q+ + N+ F E+ REP P P Y+ S+ YW +L+ Sbjct: 588 ----GQILGRRRGGNAGFGVEI--------REPLQTPQPRYKASRDVGVNLALFYWKLLA 635 Query: 900 --ARLAFVIIFQNLVMFLSVLVDWMIPDIP 927 L F+I F+N+V F D ++PD+P Sbjct: 636 VHVHLGFIIAFENVVFFFLCPNDRLVPDVP 665 >gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] Length = 494 Score = 77.8 bits (190), Expect = 5e-14 Identities = 80/279 (28%), Positives = 116/279 (41%), Gaps = 85/279 (30%) Query: 661 EECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSK 720 ++C PGGC +++ QL IIM+GKQL+ Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLN--------------------------------- 257 Query: 721 HPEQW-DLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKK 779 H E++ L P T PE +QFGF+T+FV +F LAP+F LLNN +E+ LDA K Sbjct: 258 HMEEFVGLGGGPGPDTPCLPE-----LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHK 312 Query: 780 FVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTL 839 F+ + +RP A R G S +I ++ RL Y NG Sbjct: 313 FLCKYQRPMAGRGWTSG---------SDCSCWRPCELILPRTNARSRL----GYWLNGQ- 358 Query: 840 HGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNP-YEFSKQ----- 893 Q+ + N+ F E+ REP P P Y+ S+ Sbjct: 359 -------------GQILGRRRGGNAGFGVEI--------REPLQTPQPRYKASRDVGVNL 397 Query: 894 ---YWFILS--ARLAFVIIFQNLVMFLSVLVDWMIPDIP 927 YW +L+ L F+I F+N+V F D ++PD+P Sbjct: 398 ALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 436 Score = 39.3 bits (90), Expect = 0.019 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 428 SHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEY 485 S LFD+P TVFFSIFM+ W + L + WD + +++E A S P + Sbjct: 52 SCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQE--AMPSSAPHH 107 Score = 37.0 bits (84), Expect = 0.093 Identities = 14/31 (45%), Positives = 21/31 (67%) Query: 315 YDSPEDDMNDRKLLYQEWARYGVFYKFQPID 345 Y P D+N +LLY WA +G ++K+QP+D Sbjct: 15 YQVPGSDLNSCQLLYPYWACWGYWHKYQPLD 45 >gi|10863913 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform A [Homo sapiens] Length = 973 Score = 36.2 bits (82), Expect = 0.16 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 27/105 (25%) Query: 467 LTGIEEEEERAQEHSRP--------------EYETK-VREKMLKESNQSAV--------Q 503 LT EEEE R E RP YE K +K++K++N + V Q Sbjct: 688 LTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQ 747 Query: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMIALTF 545 +E T G++DD+D+ +++ P Y+M+F ++ + + F Sbjct: 748 FIEAITVSAGEDDDDDE-CGEEKLPSCFDYVMHFLTVFWKVLFAF 791 >gi|163914373 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform D [Homo sapiens] Length = 937 Score = 36.2 bits (82), Expect = 0.16 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 27/105 (25%) Query: 467 LTGIEEEEERAQEHSRP--------------EYETK-VREKMLKESNQSAV--------Q 503 LT EEEE R E RP YE K +K++K++N + V Q Sbjct: 652 LTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQ 711 Query: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMIALTF 545 +E T G++DD+D+ +++ P Y+M+F ++ + + F Sbjct: 712 FIEAITVSAGEDDDDDE-CGEEKLPSCFDYVMHFLTVFWKVLFAF 755 >gi|163914371 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform C [Homo sapiens] Length = 960 Score = 36.2 bits (82), Expect = 0.16 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 27/105 (25%) Query: 467 LTGIEEEEERAQEHSRP--------------EYETK-VREKMLKESNQSAV--------Q 503 LT EEEE R E RP YE K +K++K++N + V Q Sbjct: 675 LTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQ 734 Query: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMIALTF 545 +E T G++DD+D+ +++ P Y+M+F ++ + + F Sbjct: 735 FIEAITVSAGEDDDDDE-CGEEKLPSCFDYVMHFLTVFWKVLFAF 778 >gi|163914369 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform B [Homo sapiens] Length = 968 Score = 36.2 bits (82), Expect = 0.16 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 27/105 (25%) Query: 467 LTGIEEEEERAQEHSRP--------------EYETK-VREKMLKESNQSAV--------Q 503 LT EEEE R E RP YE K +K++K++N + V Q Sbjct: 683 LTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQ 742 Query: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMIALTF 545 +E T G++DD+D+ +++ P Y+M+F ++ + + F Sbjct: 743 FIEAITVSAGEDDDDDE-CGEEKLPSCFDYVMHFLTVFWKVLFAF 786 >gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] Length = 818 Score = 34.3 bits (77), Expect = 0.60 Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 7/77 (9%) Query: 2 PEDIPLLPGSPR-------RLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQ 54 P + L PG R LSP + +G G G C PG Q G++ P Q Sbjct: 575 PSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQ 634 Query: 55 PCGGESTRSSSVINNYL 71 P +S + ++ L Sbjct: 635 PPADQSPHTLRKVSKKL 651 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 33.5 bits (75), Expect = 1.0 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 2 PEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQP 55 P +P++ G R P AG G QGP+ + PGPR P G PGQP Sbjct: 118 PGLVPVVTGIRGRPGP-AGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQP 170 Score = 32.0 bits (71), Expect = 3.0 Identities = 18/47 (38%), Positives = 20/47 (42%) Query: 9 PGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQP 55 P P AG RG QGP +PGP P +GG D G P Sbjct: 652 PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVP 698 >gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens] Length = 650 Score = 33.5 bits (75), Expect = 1.0 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 13/99 (13%) Query: 8 LPGSPRRLS----------PQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCG 57 + GSPR S P+ S G Q P+H + CL GP P G + + Sbjct: 454 MTGSPRSSSESHSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSC 513 Query: 58 GESTRSSSVINNYLDANEPVSLEARLSRMHFHDSQRKVD 96 GE ++ N P +L+ +R+H + K + Sbjct: 514 GEKPYRCNICG--AQFNRPANLKTH-TRIHSGEKPYKCE 549 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 33.5 bits (75), Expect = 1.0 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Query: 9 PGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQP 55 PG+ + P AG G QGP+ Q MPG R P G + DPG+P Sbjct: 736 PGAKGAMGP-AGPDGHQGPRGEQGLTGMPGIRGP---PGPSGDPGKP 778 >gi|57163987 solute carrier family 8 member 2 [Homo sapiens] Length = 921 Score = 33.5 bits (75), Expect = 1.0 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 26/101 (25%) Query: 467 LTGIEEEEERAQEHSRPEYETKVR---------------EKMLKESNQSAV--------Q 503 LT EEE R E +P R +K++K++N + V Q Sbjct: 635 LTAEEEEARRIAEMGKPVLGENCRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQ 694 Query: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMI 541 LE T GDE++E+ + ++R P Y+M+F ++ + + Sbjct: 695 FLEAITVSAGDEEEEEDGSREERLPSCFDYVMHFLTVFWKV 735 >gi|51479177 iroquois homeobox protein 1 [Homo sapiens] Length = 480 Score = 33.1 bits (74), Expect = 1.3 Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 7/63 (11%) Query: 2 PEDIPL-------LPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQ 54 P+D PL PGS R LSP A + G QG HG+ + A G P Sbjct: 277 PQDSPLGLAKEAPEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPP 336 Query: 55 PCG 57 P G Sbjct: 337 PAG 339 >gi|122939172 connexin 45 [Homo sapiens] Length = 396 Score = 33.1 bits (74), Expect = 1.3 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 113 GFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKD 172 G+ H +A + +GE K+ P + ALEE ++ E+ +M +ELE D Sbjct: 93 GYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDNEED---PMMYPEMELESD 149 Query: 173 LENKSQ 178 ENK Q Sbjct: 150 KENKEQ 155 >gi|69122473 connexin 45 [Homo sapiens] Length = 396 Score = 33.1 bits (74), Expect = 1.3 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 113 GFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKD 172 G+ H +A + +GE K+ P + ALEE ++ E+ +M +ELE D Sbjct: 93 GYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDNEED---PMMYPEMELESD 149 Query: 173 LENKSQ 178 ENK Q Sbjct: 150 KENKEQ 155 >gi|56549696 E1A binding protein p400 [Homo sapiens] Length = 3122 Score = 32.7 bits (73), Expect = 1.7 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 169 LEKDLENKSQGSIFVRIHAPWQVLAREAEFL-KIKVPTKKMYEIKAGGSIAKKFSAALQK 227 LE+D ++ S+F I ++ EAE L K K+P K M EI + A + +AA K Sbjct: 1363 LERDFWKEADLSMFDLIGLENKITRHEAELLSKKKIPRKLMEEISTSAAPAARPAAAKLK 1422 Query: 228 LSSHLQP 234 S QP Sbjct: 1423 ASRLFQP 1429 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,085,680 Number of Sequences: 37866 Number of extensions: 1873659 Number of successful extensions: 8437 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 8096 Number of HSP's gapped (non-prelim): 299 length of query: 998 length of database: 18,247,518 effective HSP length: 112 effective length of query: 886 effective length of database: 14,006,526 effective search space: 12409782036 effective search space used: 12409782036 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.