Guide to the Human Genome
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Search of human proteins with 207442675

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|207442675 RAB1A, member RAS oncogene family isoform 2 [Homo
sapiens]
         (129 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|207442675 RAB1A, member RAS oncogene family isoform 2 [Homo s...   257   2e-69
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap...   132   8e-32
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]          124   2e-29
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]            97   3e-21
gi|16933567 mel transforming oncogene [Homo sapiens]                   97   5e-21
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa...    97   5e-21
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]             97   5e-21
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]             97   5e-21
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]            94   2e-20
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]            94   3e-20
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]       91   3e-19
gi|38371739 RAB15, member RAS onocogene family [Homo sapiens]          86   8e-18
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]           77   5e-15
gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]            77   5e-15
gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]           76   8e-15
gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]            76   8e-15
gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]         75   1e-14
gi|4758984 Ras-related protein Rab-11A [Homo sapiens]                  75   1e-14
gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]          75   2e-14
gi|50234889 RAB43 protein [Homo sapiens]                               72   9e-14
gi|21361884 RAB2B protein isoform 1 [Homo sapiens]                     70   4e-13
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]            70   4e-13
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]           70   4e-13
gi|10880989 RAB18, member RAS oncogene family [Homo sapiens]           69   1e-12
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]          69   1e-12
gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]           69   1e-12
gi|82659107 ras-related GTP-binding protein 4b [Homo sapiens]          65   1e-11
gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo sa...    64   4e-11
gi|19923483 GTPase Rab14 [Homo sapiens]                                64   4e-11
gi|4758996 Ras-related protein Rab-33A [Homo sapiens]                  64   4e-11

>gi|207442675 RAB1A, member RAS oncogene family isoform 2 [Homo
           sapiens]
          Length = 129

 Score =  257 bits (656), Expect = 2e-69
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
           MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
Sbjct: 1   MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60

Query: 61  KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP 120
           KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
Sbjct: 61  KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP 120

Query: 121 VKQSGGGCC 129
           VKQSGGGCC
Sbjct: 121 VKQSGGGCC 129


>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
           sapiens]
          Length = 205

 Score =  132 bits (332), Expect = 8e-32
 Identities = 65/65 (100%), Positives = 65/65 (100%)

Query: 65  EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQS 124
           EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQS
Sbjct: 141 EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQS 200

Query: 125 GGGCC 129
           GGGCC
Sbjct: 201 GGGCC 205



 Score =  129 bits (324), Expect = 6e-31
 Identities = 64/64 (100%), Positives = 64/64 (100%)

Query: 1  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
          MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
Sbjct: 1  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60

Query: 61 KLQI 64
          KLQI
Sbjct: 61 KLQI 64


>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  124 bits (311), Expect = 2e-29
 Identities = 61/61 (100%), Positives = 61/61 (100%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ
Sbjct: 1  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 60

Query: 64 I 64
          I
Sbjct: 61 I 61



 Score =  112 bits (281), Expect = 6e-26
 Identities = 58/75 (77%), Positives = 64/75 (85%), Gaps = 4/75 (5%)

Query: 55  LDGKTIKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNV 114
           +D  T K   EFADSLGIPFLETSAKNATNVEQ+FMTMAAEIKKRMGPGA +GG E+ N+
Sbjct: 131 VDNTTAK---EFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGG-ERPNL 186

Query: 115 KIQSTPVKQSGGGCC 129
           KI STPVK +GGGCC
Sbjct: 187 KIDSTPVKPAGGGCC 201


>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score = 97.4 bits (241), Expect = 3e-21
 Identities = 46/61 (75%), Positives = 53/61 (86%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          M   YDYLFKLLLIGDSGVGK+CLL RF++D +  ++ISTIG+DFKIRTIELDGK IKLQ
Sbjct: 1  MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQ 60

Query: 64 I 64
          I
Sbjct: 61 I 61



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 24/57 (42%), Positives = 34/57 (59%), Gaps = 10/57 (17%)

Query: 61  KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM------GPGATAGGAEK 111
           KL I++    GI FLETSAK++ NVE++F T+A +I  ++         A AGG  K
Sbjct: 138 KLAIDY----GIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVK 190


>gi|16933567 mel transforming oncogene [Homo sapiens]
          Length = 207

 Score = 96.7 bits (239), Expect = 5e-21
 Identities = 45/61 (73%), Positives = 53/61 (86%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          M   YDYLFKLLLIGDSGVGK+C+L RF++D +  ++ISTIG+DFKIRTIELDGK IKLQ
Sbjct: 1  MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ 60

Query: 64 I 64
          I
Sbjct: 61 I 61



 Score = 43.1 bits (100), Expect = 6e-05
 Identities = 22/53 (41%), Positives = 31/53 (58%)

Query: 71  GIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQ 123
           GI F+ETSAK   NVE +F T+A +IK +M         + SN  ++ TP +Q
Sbjct: 144 GIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQ 196


>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
           family [Homo sapiens]
          Length = 327

 Score = 96.7 bits (239), Expect = 5e-21
 Identities = 42/64 (65%), Positives = 57/64 (89%)

Query: 1   MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
           +S+M   YD+LFKLLLIGDSGVGK+CL++RFA+D +  +YISTIG+DFKIRT++++GK I
Sbjct: 122 VSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKI 181

Query: 61  KLQI 64
           KLQ+
Sbjct: 182 KLQV 185



 Score = 40.0 bits (92), Expect = 5e-04
 Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 4/68 (5%)

Query: 61  KLQIEFADSL----GIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKI 116
           K+Q E AD L    GI F ETSAK++ NV+++F ++A +I  + G   +  G +  +  +
Sbjct: 254 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDL 313

Query: 117 QSTPVKQS 124
           ++  +K +
Sbjct: 314 KTCDIKNT 321


>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score = 96.7 bits (239), Expect = 5e-21
 Identities = 42/64 (65%), Positives = 57/64 (89%)

Query: 1   MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
           +S+M   YD+LFKLLLIGDSGVGK+CL++RFA+D +  +YISTIG+DFKIRT++++GK I
Sbjct: 122 VSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKI 181

Query: 61  KLQI 64
           KLQ+
Sbjct: 182 KLQV 185



 Score = 40.0 bits (92), Expect = 5e-04
 Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 4/68 (5%)

Query: 61  KLQIEFADSL----GIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKI 116
           K+Q E AD L    GI F ETSAK++ NV+++F ++A +I  + G   +  G +  +  +
Sbjct: 254 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDL 313

Query: 117 QSTPVKQS 124
           ++  +K +
Sbjct: 314 KTCDIKNT 321


>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score = 96.7 bits (239), Expect = 5e-21
 Identities = 42/64 (65%), Positives = 57/64 (89%)

Query: 1   MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
           +S+M   YD+LFKLLLIGDSGVGK+CL++RFA+D +  +YISTIG+DFKIRT++++GK I
Sbjct: 122 VSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKI 181

Query: 61  KLQI 64
           KLQ+
Sbjct: 182 KLQV 185



 Score = 40.0 bits (92), Expect = 5e-04
 Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 4/68 (5%)

Query: 61  KLQIEFADSL----GIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKI 116
           K+Q E AD L    GI F ETSAK++ NV+++F ++A +I  + G   +  G +  +  +
Sbjct: 254 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDL 313

Query: 117 QSTPVKQS 124
           ++  +K +
Sbjct: 314 KTCDIKNT 321


>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score = 94.4 bits (233), Expect = 2e-20
 Identities = 41/61 (67%), Positives = 54/61 (88%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          M   YD+LFKLLLIGDSGVGK+CL++RFA+D +  +YISTIG+DFKIRT++++GK IKLQ
Sbjct: 1  MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ 60

Query: 64 I 64
          +
Sbjct: 61 V 61



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 4/68 (5%)

Query: 61  KLQIEFADSL----GIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKI 116
           K+Q E AD L    GI F ETSAK++ NV+++F ++A +I  + G   +  G +  +  +
Sbjct: 130 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDL 189

Query: 117 QSTPVKQS 124
           ++   K +
Sbjct: 190 KTCDKKNT 197


>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score = 94.0 bits (232), Expect = 3e-20
 Identities = 44/61 (72%), Positives = 56/61 (91%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          M  +YD+LFKLL+IGDSGVGKS LLLRFAD+T++ SYI+TIGVDFKIRT+E++G+ +KLQ
Sbjct: 1  MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ 60

Query: 64 I 64
          I
Sbjct: 61 I 61



 Score = 30.8 bits (68), Expect = 0.31
 Identities = 17/65 (26%), Positives = 28/65 (43%)

Query: 65  EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQS 124
           +FA  +GI   ETSAK   NVE+ F  +   + +           ++ N  ++ T   + 
Sbjct: 137 KFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKR 196

Query: 125 GGGCC 129
              CC
Sbjct: 197 KKRCC 201


>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
          Length = 200

 Score = 90.5 bits (223), Expect = 3e-19
 Identities = 41/57 (71%), Positives = 50/57 (87%)

Query: 8  YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          YD LFKLLLIGDSGVGK+C+L RF+DD +  ++ISTIG+DFKI+T+EL GK IKLQI
Sbjct: 6  YDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQI 62



 Score = 33.5 bits (75), Expect = 0.048
 Identities = 15/35 (42%), Positives = 24/35 (68%)

Query: 65  EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKR 99
           + A   GI F ETSAK   N+E++F+T+A +I ++
Sbjct: 139 QIAREHGIRFFETSAKANINIEKAFLTLAEDILRK 173


>gi|38371739 RAB15, member RAS onocogene family [Homo sapiens]
          Length = 208

 Score = 85.9 bits (211), Expect = 8e-18
 Identities = 44/77 (57%), Positives = 58/77 (75%), Gaps = 2/77 (2%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          M  +YD LF+LLLIGDSGVGK+CLL RF D+ +  S+ISTIGVDFK++TIE+DG  IK++
Sbjct: 1  MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDG--IKVR 58

Query: 64 IEFADSLGIPFLETSAK 80
          I+  D+ G    +T  K
Sbjct: 59 IQIWDTAGQERYQTITK 75


>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
          Length = 227

 Score = 76.6 bits (187), Expect = 5e-15
 Identities = 32/62 (51%), Positives = 50/62 (80%)

Query: 3  SMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKL 62
          S +  +DY+FKLL+IG+S VGK+  L R+ADD++T +++ST+G+DFK++T+  + K IKL
Sbjct: 22 SSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKL 81

Query: 63 QI 64
          QI
Sbjct: 82 QI 83



 Score = 33.1 bits (74), Expect = 0.062
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 68  DSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGA---TAGGAEKSNVKIQSTP 120
           + LG  F ETSAK+  NV+Q+F  +   I  +M        A  A K N +++ TP
Sbjct: 163 EQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQNTRLKETP 218


>gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]
          Length = 220

 Score = 76.6 bits (187), Expect = 5e-15
 Identities = 32/62 (51%), Positives = 50/62 (80%)

Query: 3  SMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKL 62
          S +  +DY+FK+L+IG+S VGK+  L R+ADD++T +++ST+G+DFK++TI  + K IKL
Sbjct: 14 SSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKL 73

Query: 63 QI 64
          QI
Sbjct: 74 QI 75



 Score = 32.0 bits (71), Expect = 0.14
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 65  EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPG------ATAGGAEKSNVKIQS 118
           + AD LG  F E SAK+  NV+Q+F  +   I ++M         A  G  +   +  Q 
Sbjct: 152 QLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLSDQQ 211

Query: 119 TPVKQ 123
            P  Q
Sbjct: 212 VPPHQ 216


>gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]
          Length = 219

 Score = 75.9 bits (185), Expect = 8e-15
 Identities = 31/57 (54%), Positives = 47/57 (82%)

Query: 8  YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          +DY+FKLL+IG+S VGK+  L R+ADDT+T +++ST+G+DFK++T+    K +KLQI
Sbjct: 19 FDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQI 75



 Score = 27.7 bits (60), Expect = 2.6
 Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 4/66 (6%)

Query: 67  ADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAG----GAEKSNVKIQSTPVK 122
           A+ LG  F E SAK   +V Q+F  +   I  +M           G+ K+     + P+ 
Sbjct: 154 AEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSSKNTRLSDTPPLL 213

Query: 123 QSGGGC 128
           Q    C
Sbjct: 214 QQNCSC 219


>gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]
          Length = 219

 Score = 75.9 bits (185), Expect = 8e-15
 Identities = 32/57 (56%), Positives = 47/57 (82%)

Query: 8  YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          +DY+FKLLLIG+S VGK+  L R+ADD++T +++ST+G+DFK++T+    K IKLQI
Sbjct: 19 FDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQI 75



 Score = 32.7 bits (73), Expect = 0.081
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 3/66 (4%)

Query: 67  ADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVK---IQSTPVKQ 123
           AD LG  F E SAK   NV+Q F  +   I ++M        +  SN K   +   P  Q
Sbjct: 154 ADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSSSSGSNGKGPAVGDAPAPQ 213

Query: 124 SGGGCC 129
                C
Sbjct: 214 PSSCSC 219


>gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score = 75.5 bits (184), Expect = 1e-14
 Identities = 38/64 (59%), Positives = 48/64 (75%)

Query: 1  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
          M + + EYDYLFK++LIGDSGVGKS LL RF  + +     STIGV+F  R+I++DGKTI
Sbjct: 1  MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTI 60

Query: 61 KLQI 64
          K QI
Sbjct: 61 KAQI 64



 Score = 33.5 bits (75), Expect = 0.048
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 5/65 (7%)

Query: 66  FADSLGIPFLETSAKNATNVEQSFMTMAAEI-----KKRMGPGATAGGAEKSNVKIQSTP 120
           FA+   + F+ETSA ++TNVE++F  +  EI     +K++   A    +  +NV   S P
Sbjct: 142 FAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVP 201

Query: 121 VKQSG 125
               G
Sbjct: 202 PTTDG 206


>gi|4758984 Ras-related protein Rab-11A [Homo sapiens]
          Length = 216

 Score = 75.5 bits (184), Expect = 1e-14
 Identities = 38/64 (59%), Positives = 48/64 (75%)

Query: 1  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
          M + + EYDYLFK++LIGDSGVGKS LL RF  + +     STIGV+F  R+I++DGKTI
Sbjct: 1  MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTI 60

Query: 61 KLQI 64
          K QI
Sbjct: 61 KAQI 64



 Score = 36.2 bits (82), Expect = 0.007
 Identities = 16/31 (51%), Positives = 23/31 (74%)

Query: 66  FADSLGIPFLETSAKNATNVEQSFMTMAAEI 96
           FA+  G+ F+ETSA ++TNVE +F T+  EI
Sbjct: 142 FAEKNGLSFIETSALDSTNVEAAFQTILTEI 172


>gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]
          Length = 217

 Score = 74.7 bits (182), Expect = 2e-14
 Identities = 30/57 (52%), Positives = 46/57 (80%)

Query: 8  YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          +DYLFK++LIGDS VGK+C++  F    YTE+  +TIGVDF +R++++DGK +K+Q+
Sbjct: 14 FDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQV 70



 Score = 29.6 bits (65), Expect = 0.69
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 1/52 (1%)

Query: 75  LETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGG 126
           LETSAK + N+E+ F+ MA E+  R       G +  + + + S+PV  + G
Sbjct: 158 LETSAKESKNIEEVFVLMAKELIAR-NSLHLYGESALNGLPLDSSPVLMAQG 208


>gi|50234889 RAB43 protein [Homo sapiens]
          Length = 212

 Score = 72.4 bits (176), Expect = 9e-14
 Identities = 31/58 (53%), Positives = 46/58 (79%)

Query: 7  EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          +YD+LFKL+L+GD+ VGK+C++ RF    ++E   STIGVDF ++T+E+ GK +KLQI
Sbjct: 14 QYDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQI 71



 Score = 33.5 bits (75), Expect = 0.048
 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 75  LETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGC 128
           +ETSAK+++NVE++F+ +A E+  R G G         ++++ S  + + G GC
Sbjct: 159 IETSAKDSSNVEEAFLRVATELIMRHG-GPLFSEKSPDHIQLNSKDIGE-GWGC 210


>gi|21361884 RAB2B protein isoform 1 [Homo sapiens]
          Length = 216

 Score = 70.5 bits (171), Expect = 4e-13
 Identities = 33/57 (57%), Positives = 42/57 (73%)

Query: 8  YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          Y YLFK ++IGD+GVGKSCLLL+F D  +   +  TIGV+F  R + +DGK IKLQI
Sbjct: 3  YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQI 59



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 21/51 (41%), Positives = 31/51 (60%)

Query: 66  FADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKI 116
           FA   G+ F+ETSAK A NVE++F+  A EI +++  G      E + +KI
Sbjct: 137 FAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKI 187


>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
          Length = 212

 Score = 70.5 bits (171), Expect = 4e-13
 Identities = 34/57 (59%), Positives = 42/57 (73%)

Query: 8  YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          Y YLFK ++IGD+GVGKSCLLL+F D  +   +  TIGV+F  R I +DGK IKLQI
Sbjct: 3  YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQI 59



 Score = 46.2 bits (108), Expect = 7e-06
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 12/76 (15%)

Query: 66  FADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPV---- 121
           FA   G+ F+ETSAK A+NVE++F+  A EI +++  G      E + +KI         
Sbjct: 137 FAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNA 196

Query: 122 --------KQSGGGCC 129
                   +Q+GGGCC
Sbjct: 197 THAGNQGGQQAGGGCC 212


>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score = 70.5 bits (171), Expect = 4e-13
 Identities = 30/58 (51%), Positives = 46/58 (79%)

Query: 7  EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          +YD+LFK++LIG++GVGK+CL+ RF    +     +TIGVDF I+T+E++G+ +KLQI
Sbjct: 5  DYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQI 62



 Score = 33.9 bits (76), Expect = 0.037
 Identities = 19/63 (30%), Positives = 35/63 (55%)

Query: 34  DTYTESYISTIGVDFKIRTIELDGKTIKLQIEFADSLGIPFLETSAKNATNVEQSFMTMA 93
           + Y  + + T+ V  KI   E    + +   EF+++  + +LETSAK + NVE+ F+ +A
Sbjct: 108 EQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167

Query: 94  AEI 96
             +
Sbjct: 168 CRL 170


>gi|10880989 RAB18, member RAS oncogene family [Homo sapiens]
          Length = 206

 Score = 68.6 bits (166), Expect = 1e-12
 Identities = 32/52 (61%), Positives = 40/52 (76%)

Query: 13 KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          K+L+IG+SGVGKS LLLRF DDT+     +TIGVDFK++TI +DG   KL I
Sbjct: 10 KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAI 61



 Score = 29.6 bits (65), Expect = 0.69
 Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 2/65 (3%)

Query: 64  IEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQ 123
           ++FA    + F+E SAK    V+ +F  +  +I +   PG      +   VK+      Q
Sbjct: 137 LKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQT--PGLWESENQNKGVKLSHREEGQ 194

Query: 124 SGGGC 128
            GG C
Sbjct: 195 GGGAC 199


>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
          Length = 244

 Score = 68.6 bits (166), Expect = 1e-12
 Identities = 31/56 (55%), Positives = 44/56 (78%)

Query: 9  DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          D+  ++++IG  GVGK+ L+ RF DDT+ E+  ST+GVDFKI+T+EL GK I+LQI
Sbjct: 40 DFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQI 95



 Score = 28.9 bits (63), Expect = 1.2
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 65  EFADSL-GIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP 120
           +FA  + G+ F E SAK+  NV++ F+ +  +I K+M           S + +Q  P
Sbjct: 172 KFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEP 228


>gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]
          Length = 256

 Score = 68.6 bits (166), Expect = 1e-12
 Identities = 29/58 (50%), Positives = 46/58 (79%), Gaps = 1/58 (1%)

Query: 8   YDYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQI 64
           YD  FK++L+GDSGVGK+CLL+RF D  +   ++IST+G+DF+ + +++DG  +KLQ+
Sbjct: 60  YDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQM 117



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 16/35 (45%), Positives = 24/35 (68%)

Query: 65  EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKR 99
           + A   G+PF+ETSAK   NV+ +F  +A E+K+R
Sbjct: 194 KLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQR 228


>gi|82659107 ras-related GTP-binding protein 4b [Homo sapiens]
          Length = 213

 Score = 65.1 bits (157), Expect = 1e-11
 Identities = 30/61 (49%), Positives = 42/61 (68%)

Query: 4  MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
          M   YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQ
Sbjct: 1  MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60

Query: 64 I 64
          I
Sbjct: 61 I 61



 Score = 29.6 bits (65), Expect = 0.69
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 66  FADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPG 103
           FA    + FLETSA    NVE++F+  A  I  ++  G
Sbjct: 139 FAQENELMFLETSALTGENVEEAFLKCARTILNKIDSG 176


>gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo
          sapiens]
          Length = 223

 Score = 63.5 bits (153), Expect = 4e-11
 Identities = 26/61 (42%), Positives = 46/61 (75%), Gaps = 1/61 (1%)

Query: 5  NPEYDYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQ 63
          +P YD   K++L+GD+GVGK+C L++F D  + + ++I+T+G+DF+ + + +DG  +KLQ
Sbjct: 23 SPSYDLTGKVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQ 82

Query: 64 I 64
          I
Sbjct: 83 I 83



 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 22/46 (47%), Positives = 29/46 (63%), Gaps = 6/46 (13%)

Query: 56  DGKTIKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMG 101
           DG+T+      A   G+PFLETSAK   NVE +F+ +A E+K R G
Sbjct: 157 DGETL------AREYGVPFLETSAKTGMNVELAFLAIAKELKYRAG 196


>gi|19923483 GTPase Rab14 [Homo sapiens]
          Length = 215

 Score = 63.5 bits (153), Expect = 4e-11
 Identities = 31/64 (48%), Positives = 42/64 (65%)

Query: 1  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI 60
          M++    Y Y+FK ++IGD GVGKSCLL +F +  +      TIGV+F  R IE+ G+ I
Sbjct: 1  MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKI 60

Query: 61 KLQI 64
          KLQI
Sbjct: 61 KLQI 64



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 2/62 (3%)

Query: 65  EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQS 124
           +FA+  G+ FLE SAK   NVE +F+  A +I + +  G+    A +S V  Q  P    
Sbjct: 141 QFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGV--QHKPSAPQ 198

Query: 125 GG 126
           GG
Sbjct: 199 GG 200


>gi|4758996 Ras-related protein Rab-33A [Homo sapiens]
          Length = 237

 Score = 63.5 bits (153), Expect = 4e-11
 Identities = 26/54 (48%), Positives = 42/54 (77%)

Query: 11 LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQI 64
          +FK+++IGDS VGK+CL  RF   T+ +   +TIGVDF+ +T+E++G+ IK+Q+
Sbjct: 36 IFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQV 89



 Score = 29.6 bits (65), Expect = 0.69
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 5/65 (7%)

Query: 62  LQIEFADSLGIPFLETSAKN---ATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQS 118
           L ++FAD+  +   ETSAK+   + NVE  FM +A  +K +         AE+   K+Q 
Sbjct: 165 LALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQ--KSLLYRDAERQQGKVQK 222

Query: 119 TPVKQ 123
               Q
Sbjct: 223 LEFPQ 227


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,297,909
Number of Sequences: 37866
Number of extensions: 143536
Number of successful extensions: 760
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 494
Number of HSP's gapped (non-prelim): 292
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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