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Search of human proteins with 206597513
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
(1205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 2437 0.0
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 2437 0.0
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 1572 0.0
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 847 0.0
gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 721 0.0
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 104 4e-22
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 103 8e-22
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 102 2e-21
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 100 1e-20
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 99 2e-20
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 97 7e-20
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 97 7e-20
gi|156119615 myosin IXA [Homo sapiens] 97 9e-20
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 96 2e-19
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 96 2e-19
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 96 3e-19
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 96 3e-19
gi|46094081 development and differentiation enhancing factor 1 [... 95 5e-19
gi|187608516 centaurin, beta 2 [Homo sapiens] 95 5e-19
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 95 5e-19
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 92 2e-18
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 92 2e-18
gi|188497642 ARHGAP15 [Homo sapiens] 92 4e-18
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 91 7e-18
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 91 7e-18
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 91 7e-18
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 91 9e-18
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 91 9e-18
gi|56119110 family with sequence similarity 13, member A1 isofor... 91 9e-18
gi|208022687 GTPase regulator associated with the focal adhesion... 88 4e-17
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform a [Homo sapiens]
Length = 1205
Score = 2437 bits (6316), Expect = 0.0
Identities = 1205/1205 (100%), Positives = 1205/1205 (100%)
Query: 1 MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL 60
MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL
Sbjct: 1 MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL 60
Query: 61 PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD 120
PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD
Sbjct: 61 PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD 120
Query: 121 AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA 180
AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA
Sbjct: 121 AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA 180
Query: 181 RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM 240
RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM
Sbjct: 181 RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM 240
Query: 241 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA 300
SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA
Sbjct: 241 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA 300
Query: 301 PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF 360
PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF
Sbjct: 301 PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF 360
Query: 361 LQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKA 420
LQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKA
Sbjct: 361 LQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKA 420
Query: 421 LCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVP 480
LCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVP
Sbjct: 421 LCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVP 480
Query: 481 RLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFE 540
RLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFE
Sbjct: 481 RLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFE 540
Query: 541 NERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCI 600
NERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCI
Sbjct: 541 NERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCI 600
Query: 601 AKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQ 660
AKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQ
Sbjct: 601 AKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQ 660
Query: 661 LRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQL 720
LRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQL
Sbjct: 661 LRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQL 720
Query: 721 GDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVD 780
GDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVD
Sbjct: 721 GDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVD 780
Query: 781 DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL 840
DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL
Sbjct: 781 DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL 840
Query: 841 ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEE 900
ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEE
Sbjct: 841 ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEE 900
Query: 901 LRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLE 960
LRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLE
Sbjct: 901 LRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLE 960
Query: 961 ILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAM 1020
ILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAM
Sbjct: 961 ILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAM 1020
Query: 1021 LLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG 1080
LLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG
Sbjct: 1021 LLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG 1080
Query: 1081 APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR 1140
APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR
Sbjct: 1081 APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR 1140
Query: 1141 EWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLS 1200
EWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLS
Sbjct: 1141 EWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLS 1200
Query: 1201 LLRNV 1205
LLRNV
Sbjct: 1201 LLRNV 1205
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
isoform c [Homo sapiens]
Length = 1450
Score = 2437 bits (6316), Expect = 0.0
Identities = 1205/1205 (100%), Positives = 1205/1205 (100%)
Query: 1 MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL 60
MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL
Sbjct: 246 MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL 305
Query: 61 PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD 120
PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD
Sbjct: 306 PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD 365
Query: 121 AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA 180
AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA
Sbjct: 366 AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA 425
Query: 181 RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM 240
RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM
Sbjct: 426 RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM 485
Query: 241 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA 300
SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA
Sbjct: 486 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA 545
Query: 301 PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF 360
PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF
Sbjct: 546 PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF 605
Query: 361 LQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKA 420
LQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKA
Sbjct: 606 LQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKA 665
Query: 421 LCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVP 480
LCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVP
Sbjct: 666 LCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVP 725
Query: 481 RLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFE 540
RLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFE
Sbjct: 726 RLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFE 785
Query: 541 NERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCI 600
NERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCI
Sbjct: 786 NERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCI 845
Query: 601 AKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQ 660
AKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQ
Sbjct: 846 AKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQ 905
Query: 661 LRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQL 720
LRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQL
Sbjct: 906 LRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQL 965
Query: 721 GDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVD 780
GDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVD
Sbjct: 966 GDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVD 1025
Query: 781 DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL 840
DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL
Sbjct: 1026 DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL 1085
Query: 841 ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEE 900
ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEE
Sbjct: 1086 ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEE 1145
Query: 901 LRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLE 960
LRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLE
Sbjct: 1146 LRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLE 1205
Query: 961 ILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAM 1020
ILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAM
Sbjct: 1206 ILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAM 1265
Query: 1021 LLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG 1080
LLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG
Sbjct: 1266 LLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG 1325
Query: 1081 APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR 1140
APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR
Sbjct: 1326 APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR 1385
Query: 1141 EWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLS 1200
EWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLS
Sbjct: 1386 EWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLS 1445
Query: 1201 LLRNV 1205
LLRNV
Sbjct: 1446 LLRNV 1450
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform d [Homo sapiens]
Length = 1133
Score = 1572 bits (4071), Expect = 0.0
Identities = 819/1022 (80%), Positives = 863/1022 (84%), Gaps = 78/1022 (7%)
Query: 242 VGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAP 301
+ +V + + F++ T R F+F A+S++E+++W++A+Q A+AE + + ++ P
Sbjct: 132 ISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP 191
Query: 302 NRFCADCGAPQPDWAS---------------INLCVVICKRCAGEHRGLGA-----GVSK 341
G+ QPD A + V + K H G+G V
Sbjct: 192 -------GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGN 244
Query: 342 VRSL--------------------KMDRKVWTETLIELFLQL--GNGAGNRFWAANVPPS 379
V+ + +++++ W E + + + R WAA P+
Sbjct: 245 VKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAA--APN 302
Query: 380 EALQPSSSP-----STRRCHLEAKYREGKYR-------RYHPLFGNQ----EELDKALCA 423
+P S C + K G++R + L ++ E L +ALCA
Sbjct: 303 RFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCA 362
Query: 424 AVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLD 483
AVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLD
Sbjct: 363 AVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLD 422
Query: 484 SMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENER 543
SMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENER
Sbjct: 423 SMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENER 482
Query: 544 AVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKA 603
AVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKA
Sbjct: 483 AVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKA 542
Query: 604 FVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRK 663
FVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRK
Sbjct: 543 FVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRK 602
Query: 664 LQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDS 723
LQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDS
Sbjct: 603 LQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDS 662
Query: 724 DIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVS 783
DIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVS
Sbjct: 663 DIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVS 722
Query: 784 SALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISH 843
SALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISH
Sbjct: 723 SALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISH 782
Query: 844 LYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRK 903
LYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRK
Sbjct: 783 LYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRK 842
Query: 904 QREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILD 963
QREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILD
Sbjct: 843 QREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILD 902
Query: 964 RRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLY 1023
RRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLY
Sbjct: 903 RRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLY 962
Query: 1024 LASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSGAPE 1083
LASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVR
Sbjct: 963 LASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVR---------- 1012
Query: 1084 TSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELREWF 1143
SHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELREWF
Sbjct: 1013 -SHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELREWF 1071
Query: 1144 ATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLSLLR 1203
ATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLSLLR
Sbjct: 1072 ATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFTADPLSLLR 1131
Query: 1204 NV 1205
NV
Sbjct: 1132 NV 1133
Score = 728 bits (1880), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL 60
MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL
Sbjct: 1 MTKKEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSL 60
Query: 61 PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD 120
PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD
Sbjct: 61 PSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD 120
Query: 121 AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA 180
AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA
Sbjct: 121 AYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARA 180
Query: 181 RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM 240
RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM
Sbjct: 181 RLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDM 240
Query: 241 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA 300
SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA
Sbjct: 241 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAA 300
Query: 301 PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIE 358
PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIE
Sbjct: 301 PNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIE 358
>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
[Homo sapiens]
Length = 1704
Score = 847 bits (2188), Expect = 0.0
Identities = 469/1140 (41%), Positives = 682/1140 (59%), Gaps = 63/1140 (5%)
Query: 84 IKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKF 143
+K+GWLDK PQG ++QKRWV+ D + Y+++ K+ YSK I ++ IS V GD KF
Sbjct: 484 VKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGDNKF 543
Query: 144 EVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLE 203
EV+T RTF FR E + ER +W+ L A+ Q ++ + P++ G LE
Sbjct: 544 EVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVT--------PEKCGYLE 595
Query: 204 LRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDR---RSFDLTTPYR 260
LRG+K K++ + G+ V L KN +++ G+GIT I M+V NVK+VDR +SF++ TPYR
Sbjct: 596 LRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYR 655
Query: 261 IFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINL 320
FSF+A++E EK+ W+EA+Q +IAE LS EVAE+IW NR CADC AP PDWASINL
Sbjct: 656 SFSFTAETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINL 715
Query: 321 CVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSE 380
CVVICK+CAG+HR LG SKVRSLKMD +W+ LIELF+ +GN N FWA N+ E
Sbjct: 716 CVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDE 775
Query: 381 ALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCG 440
L S R+ + KY+EGK+R+ +EEL+KALCAAV D+ ET ALL G
Sbjct: 776 ELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSG 835
Query: 441 AGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVS 500
A + C +GDP TP LA++AGQ+LQMEFL +N+ ++ P+ D H VL S
Sbjct: 836 ADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDI------HSEGVLSQES 889
Query: 501 HSG-----FLYKTAS-AGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRAS 554
FLY+ S A KL +++ EE +++WCVL G LSY+EN+++ TPNG I +
Sbjct: 890 SQSTFLCDFLYQAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININ 949
Query: 555 EIVCLAVPPPDTH---GFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAED 611
E++CLA+ D + G FE+Y ER++LFG E+++ +W + IAK FVP AE+
Sbjct: 950 EVICLAIHKEDFYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAEN 1009
Query: 612 LLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCE-EPLQLRKLQELSI- 669
L D++ +G+L YK +L + ++GWF++ S L + + + LR+LQEL+I
Sbjct: 1010 LTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTIS 1069
Query: 670 ---QGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIP 726
Q + VL+LVE+ RTLYI G +LDF W AI+KAA + G+ L +QQL +D+P
Sbjct: 1070 TMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVP 1129
Query: 727 VIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSAL 786
+IV C+ ++TQ GL + IY+K G LLES ++DARS L+ G+ ++DV++ L
Sbjct: 1130 IIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVL 1189
Query: 787 KRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYC 846
K FL D+ D L T+ W+ A + +D++E++ +Y + LP VNRAT+ A+I HLY
Sbjct: 1190 KSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYR 1249
Query: 847 VQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQRE 906
VQ S+ N MN HNLA+VF LFQT GQ + V+EDLIN+YV +F V E+++++
Sbjct: 1250 VQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDI 1309
Query: 907 EITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRN 966
E + I K + + AGD + VY+E K+ + I++ M AEELT +IL +N
Sbjct: 1310 ENSFITKWK----DTQVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKN 1365
Query: 967 VGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT-----DSHLVVKKHQAMEAML 1021
+ + D W FEV E EE ERPLH+ E VL + + ++LVVK+ + +
Sbjct: 1366 IIPTKGDIWATFEVIENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIK 1425
Query: 1022 -LYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSG 1080
S +G K G++K +E+ S + L F DRYF+L L LYK+V+S
Sbjct: 1426 HCSDRSTLGSIKEGILKIKEEPSKI---LSGNKFQDRYFVLRDGFLFLYKDVKSS----- 1477
Query: 1081 APETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELR 1140
+ +K + + S+K Y GVKKK++PPT WG T EK W+LCCD+
Sbjct: 1478 ------KHDKMFSLSSMKFYRGVKKKMKPPTSWGLTAY-----SEKHHWHLCCDSSRTQT 1526
Query: 1141 EWFATFLFVQHDGLVWPSEPSRVSRAVPE-VRLGSVSLIPLR--GSENEMRRSVAAFTAD 1197
EW + QH+ +WP R++ + ++G + LIP++ G+ R+++ + A+
Sbjct: 1527 EWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIGGLPLIPIQHEGNATLARKNIESARAE 1586
>gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
[Homo sapiens]
Length = 1544
Score = 721 bits (1860), Expect = 0.0
Identities = 433/1136 (38%), Positives = 624/1136 (54%), Gaps = 92/1136 (8%)
Query: 80 VTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIG 139
+TP++ +GWLDK PQG+Y++Q+R+V+ + L YF S+KD + K I + I +
Sbjct: 286 LTPLL-SGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSK 344
Query: 140 DQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDR- 198
D KF+VIT R F FR ES+ +R W LQ + EQR LLG P QP R
Sbjct: 345 DNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQR---------LLGHPRPPQPPRP 395
Query: 199 --AGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLT 256
G LELRG K K++ A+ ++ LYK+ + + LGIGI FI++ +V+E RSFDL
Sbjct: 396 LRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLL 455
Query: 257 TPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWA 316
TP+R FSF+A+S ++ W A+Q A+ E LS EVAE+IW+ NR CADCG+ +PDWA
Sbjct: 456 TPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWA 515
Query: 317 SINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANV 376
++NL VVICK+CAG+HR LG+G+SKV+SLK+D VW+ +++LF+ LGN NRFWA +
Sbjct: 516 AVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTL 575
Query: 377 PPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQAL 436
PP E L P ++P R + KYR G +R+ HP + + +L +ALCAAV +L +
Sbjct: 576 PPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQ 635
Query: 437 LGCGAGINCFSGD----PEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHY 492
L C + F G+ P AP P L P Y
Sbjct: 636 LLC---VEAFEGEEPWFPPAP----------------------DGSCPGLLPSDPSPGVY 670
Query: 493 SVVLPTVSHSGFLYKTASAGKL--LQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGE 550
+ V+ ++SGFLY + + K RR R+ R WCVLG L F +E + P
Sbjct: 671 NEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLG-AALEMFASENSPEPLSL 729
Query: 551 IRASEIVCLAVPPPDT---HGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPP 607
I+ +IVCL V PP T F +FE+ G R+ FG + A+ W + K F P
Sbjct: 730 IQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPL 789
Query: 608 LAEDLLARDFERLGRLPYKAGLSLQRAQEGWFS----LSGSELRAVFPEGP----CEEPL 659
LL RLGRL ++ A W S L G L GP E+ +
Sbjct: 790 SCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMV 849
Query: 660 QLRKLQELSIQGDSE----NQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTL 715
LR+LQE+S+ ++ + LVLVE RTLY+QGE RLDF W AI AA G L
Sbjct: 850 HLRRLQEISVVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFTAWNAAIGGAAGGGGTGL 909
Query: 716 SEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEG 775
EQQ+ DIP+IV C+ ++TQ GL EG+YRK G +++ RLL R+DARSV L+ G
Sbjct: 910 QEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPG 969
Query: 776 EQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA 835
E V+DV+ LKRF R+L D + + W EA+E+ + +++ +Y++++ LP VNR
Sbjct: 970 EHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRR 1029
Query: 836 TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFS 895
T+ LI HLY VQ + NQM NLA++F P++FQTDG+ RV+++LI+ Y+ VF
Sbjct: 1030 TLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFD 1089
Query: 896 VDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAE 955
+D +++ + E++ I + + AGD I VY+E++ + +KV ++TAE
Sbjct: 1090 IDSDQVAQIDLEVSLITTWKDVQLS----QAGDLIMEVYIEQQLPDNCVTLKVSPTLTAE 1145
Query: 956 ELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLP-----ILHGLGTDSHLV 1010
ELT ++L+ R D W FE+ E E ERPLH EKVL + L+
Sbjct: 1146 ELTNQVLEMRGTA-AGMDLWVTFEIREHGELERPLHPKEKVLEQALQWCQLPEPCSASLL 1204
Query: 1011 VKKHQAMEAMLLYLASRVGDTKHGMMKFRED-RSLLGLGLPSGGFHDRYFILNSSCLRLY 1069
+KK +A L+ R + G+++ RE+ LLG F +R+F+L CL L
Sbjct: 1205 LKKVPLAQAGCLFTGIRRESPRVGLLRCREEPPRLLG-----SRFQERFFLLRGRCLLLL 1259
Query: 1070 KEVRSQRPWSGAPETSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQW 1129
KE +S +PE+EWP++ KVYLG++KKL+PPT WGFT++ EK
Sbjct: 1260 KEKKSS-----------KPEREWPLEGAKVYLGIRKKLKPPTPWGFTLI-----LEKMHL 1303
Query: 1130 YLCCDTQMELREWFATFLFVQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSEN 1185
YL C + E+ +W + L QHD S + + G++ L+P+RG ++
Sbjct: 1304 YLSCTDEDEMWDWTTSILKAQHDDQQPVVLRRHSSSDLARQKFGTMPLLPIRGDDS 1359
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 104 bits (260), Expect = 4e-22
Identities = 73/248 (29%), Positives = 113/248 (45%), Gaps = 21/248 (8%)
Query: 241 SVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVA------- 293
S G +E + +++ + + F A S E++ W++A++ I +L E +
Sbjct: 511 SAGQAEEENFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTD 570
Query: 294 --------ERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSL 345
+ I A N C DCGAP P WAS+NL +IC C+G HR LG +S+VRSL
Sbjct: 571 SQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSL 630
Query: 346 KMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYR 405
+D W L + +GN NR W ++ SS R + AKY + +
Sbjct: 631 DLDD--WPRELTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLF- 687
Query: 406 RYHPLFGNQEELDKALCAAVTTTDLAETQALLGCG--AGINCFSGDPEAPTPLALAEQAG 463
PL ++E L + L AAV D+A LL ++ DP+ +PL LA +
Sbjct: 688 -LAPLSTSEEPLGRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELA 746
Query: 464 QTLQMEFL 471
+ + L
Sbjct: 747 HVVITQLL 754
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 103 bits (258), Expect = 8e-22
Identities = 71/242 (29%), Positives = 117/242 (48%), Gaps = 45/242 (18%)
Query: 209 NKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVK---EVDRR-SFDLTTPYRIFSF 264
N+ + ++ ++ K L++ + + D+ + +VK +++RR F++ +P +
Sbjct: 287 NRRWFSIQNSQLVYQKKLKD---ALTVVVDDLRLCSVKPCEDIERRFCFEVLSPTKSCML 343
Query: 265 SADSELEKEQWLEAMQGAIAEALSTS---------------------------------- 290
ADSE ++ W++A+Q +IA A S
Sbjct: 344 QADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSIDSATDTRERGVKGE 403
Query: 291 EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRK 350
V +R+ + A N C DCG P P WASINL V++C C+G HR LG SKVRSL +D
Sbjct: 404 SVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDS- 462
Query: 351 VWTETLIELFLQLGNGAGNRFWAANVPPSEALQP--SSSPSTRRCHLEAKYREGKYRRYH 408
W L++L +LGN A N+ + A + + +P SSS + ++ KY E K+ R
Sbjct: 463 -WEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKA 521
Query: 409 PL 410
P+
Sbjct: 522 PM 523
Score = 35.8 bits (81), Expect = 0.25
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 17/135 (12%)
Query: 70 MDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISV 129
+D P G V+ G+L K + +RW + L Y KDA + +
Sbjct: 263 VDAPSG-------VVMEGYLFKRASNAFKTWNRRWFSIQNSQLVYQKKLKDALTVVVDDL 315
Query: 130 ACISHVAAIGDQK---FEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAY 186
S ++ FEV++ ++ +A+S+ R+ W+QA+Q ++A R S Y
Sbjct: 316 RLCSVKPCEDIERRFCFEVLSPTKSCMLQADSEKLRQAWVQAVQASIA-SAYRESPDSCY 374
Query: 187 LLGVPGSEQPDRAGS 201
SE+ DR S
Sbjct: 375 ------SERLDRTAS 383
Score = 33.5 bits (75), Expect = 1.3
Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 416 ELDKALCA--AVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRN 473
EL L A A DL A L GA +N + E TPL A G + EFL
Sbjct: 665 ELHPGLLAHRAARARDLPALAAALAHGAEVNWADAEDEGKTPLVQAVLGGSLIVCEFLLQ 724
Query: 474 NRTTEVPRLDSMKPLEKHYSVVL-PTVSHSGFLYKTASAGKLLQDRR 519
N +V + DS H++ +L T FL + A L Q++R
Sbjct: 725 N-GADVNQRDSRGRAPLHHATLLGRTGQVCLFLKRGADQHALDQEQR 770
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 102 bits (254), Expect = 2e-21
Identities = 70/225 (31%), Positives = 103/225 (45%), Gaps = 21/225 (9%)
Query: 264 FSADSELEKEQWLEAMQGAIAEALSTSEVA---------------ERIWAAAPNRFCADC 308
F A S E++ W++A++ I +L E + + I A N C DC
Sbjct: 890 FEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDC 949
Query: 309 GAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAG 368
GAP P WAS+NL +IC C+G HR LG +S+VRSL +D W L + +GN
Sbjct: 950 GAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDD--WPRELTLVLTAIGNDTA 1007
Query: 369 NRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTT 428
NR W ++ SS R + AKY + + PL ++E L + L AAV
Sbjct: 1008 NRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLF--LAPLSTSEEPLGRQLWAAVQAQ 1065
Query: 429 DLAETQALLGCG--AGINCFSGDPEAPTPLALAEQAGQTLQMEFL 471
D+A LL ++ DP+ +PL LA + + + L
Sbjct: 1066 DVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLL 1110
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 99.8 bits (247), Expect = 1e-20
Identities = 64/185 (34%), Positives = 98/185 (52%), Gaps = 9/185 (4%)
Query: 725 IPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGE-QHVDDVS 783
+P+IV C + GL S GIYR G + L E L + ++L++ Q ++ +S
Sbjct: 825 VPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVIS 884
Query: 784 SALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISH 843
S LK F R LP+ LFT + ++EA+ IED E++ R+L+ LP T+K L+ H
Sbjct: 885 SLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGH 944
Query: 844 LYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDY--------KAGRVVEDLINHYVVVFS 895
L + S+ N+M NLA+VFGPTL +T + ++VE LI H FS
Sbjct: 945 LKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFS 1004
Query: 896 VDEEE 900
+E++
Sbjct: 1005 DEEDK 1009
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 99.0 bits (245), Expect = 2e-20
Identities = 55/152 (36%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Query: 722 DSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDD 781
+ IP+ + RC++YI GL++EGIYR G S+ + L QD ++ L E + V+
Sbjct: 1258 EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HNLDLAEKDFTVNT 1316
Query: 782 VSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALI 841
V+ A+K F +LPD L ++ +EA +I D E+K+ +E+L + P N K +I
Sbjct: 1317 VAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVI 1376
Query: 842 SHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD 873
SHL V + N M NL+I F PTL + D
Sbjct: 1377 SHLNKVSHNNKVNLMTSENLSICFWPTLMRPD 1408
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 97.4 bits (241), Expect = 7e-20
Identities = 57/196 (29%), Positives = 112/196 (57%), Gaps = 5/196 (2%)
Query: 723 SDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDV 782
+ +P+++ + ++++ GL +EG+YRK G ++T+ L ++L+ D +V L+ H +
Sbjct: 1710 ASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHA--I 1767
Query: 783 SSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALIS 842
+ LK++LR+LP+ L T AQ +L A E+ +++E+++ +L LP N +++ LI
Sbjct: 1768 TGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIF 1827
Query: 843 HLYCVQCFSDTNQMNVHNLAIVFGPTLFQ-TDGQDYKAGRVVEDLINHYVVVFSVDEEEL 901
HL V D N+M+ LAI+F P L + D D ++D++ V + +E++
Sbjct: 1828 HLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTS--MKDVLKITTCVEMLIKEQM 1885
Query: 902 RKQREEITAIVKMRVA 917
RK + ++ I ++ A
Sbjct: 1886 RKYKVKMEEISQLEAA 1901
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 97.4 bits (241), Expect = 7e-20
Identities = 57/196 (29%), Positives = 112/196 (57%), Gaps = 5/196 (2%)
Query: 723 SDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDV 782
+ +P+++ + ++++ GL +EG+YRK G ++T+ L ++L+ D +V L+ H +
Sbjct: 1710 ASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHA--I 1767
Query: 783 SSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALIS 842
+ LK++LR+LP+ L T AQ +L A E+ +++E+++ +L LP N +++ LI
Sbjct: 1768 TGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIF 1827
Query: 843 HLYCVQCFSDTNQMNVHNLAIVFGPTLFQ-TDGQDYKAGRVVEDLINHYVVVFSVDEEEL 901
HL V D N+M+ LAI+F P L + D D ++D++ V + +E++
Sbjct: 1828 HLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTS--MKDVLKITTCVEMLIKEQM 1885
Query: 902 RKQREEITAIVKMRVA 917
RK + ++ I ++ A
Sbjct: 1886 RKYKVKMEEISQLEAA 1901
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 97.1 bits (240), Expect = 9e-20
Identities = 66/219 (30%), Positives = 114/219 (52%), Gaps = 5/219 (2%)
Query: 707 AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQD 766
++ G LS D +P++V + ++YI GL +EGIYRK G T+K + L + L D
Sbjct: 2057 SSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTD 2116
Query: 767 ARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELL 826
A SV+L + HV ++S K++LRDLP+ L T +L A +++ +E + ++
Sbjct: 2117 AESVNLDDYNIHV--IASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVI 2174
Query: 827 VRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQ-TDGQDYKAGRVVED 885
+L + T++ LI HL + DTN+M+ + LAIVF P + + D D + V+D
Sbjct: 2175 DQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTD--PLQSVQD 2232
Query: 886 LINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQ 924
+ V + E++ K + + I + A + T+
Sbjct: 2233 ISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTR 2271
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 95.9 bits (237), Expect = 2e-19
Identities = 104/401 (25%), Positives = 177/401 (44%), Gaps = 57/401 (14%)
Query: 498 TVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEI- 556
T+ +G L++T +A K R ++ +S W VL GVL++F++ + G + S+
Sbjct: 128 TLDKAGVLHRTKTADK--GKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFS 185
Query: 557 ----------VCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAK---- 602
L+ P D ++ E+ + YL +S W K IA+
Sbjct: 186 TPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQE 245
Query: 603 --AFVPPLAEDLLARDF---ERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPE-GPCE 656
A +PP + DF ERLG S Q +E + A P GP
Sbjct: 246 LSAELPPEESESSRVDFGSSERLG--------SWQEKEED------ARPNAAAPALGPVG 291
Query: 657 EPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLS 716
L K++ +++ ++RR TL E+ G A L
Sbjct: 292 LESDLSKVR---------HKLRKFLQRRPTLQSLREKGYIKDQVFGCALAA-------LC 335
Query: 717 EQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGE 776
E++ S +P V +C+ + GL +G+YR G + Q+L + D R + L +G
Sbjct: 336 ERER--SRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDER-LDLDDGR 392
Query: 777 -QHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA 835
+ V ++ ALK F R+LP+ LF + ++ A +++D+ + R+L+ LP N
Sbjct: 393 WEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHD 452
Query: 836 TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQD 876
T++ L HL V + N+M+V ++AIVFGPTL + + ++
Sbjct: 453 TLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE 493
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 95.9 bits (237), Expect = 2e-19
Identities = 104/401 (25%), Positives = 177/401 (44%), Gaps = 57/401 (14%)
Query: 498 TVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEI- 556
T+ +G L++T +A K R ++ +S W VL GVL++F++ + G + S+
Sbjct: 155 TLDKAGVLHRTKTADK--GKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFS 212
Query: 557 ----------VCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAK---- 602
L+ P D ++ E+ + YL +S W K IA+
Sbjct: 213 TPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQE 272
Query: 603 --AFVPPLAEDLLARDF---ERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPE-GPCE 656
A +PP + DF ERLG S Q +E + A P GP
Sbjct: 273 LSAELPPEESESSRVDFGSSERLG--------SWQEKEED------ARPNAAAPALGPVG 318
Query: 657 EPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLS 716
L K++ +++ ++RR TL E+ G A L
Sbjct: 319 LESDLSKVR---------HKLRKFLQRRPTLQSLREKGYIKDQVFGCALAA-------LC 362
Query: 717 EQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGE 776
E++ S +P V +C+ + GL +G+YR G + Q+L + D R + L +G
Sbjct: 363 ERER--SRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDER-LDLDDGR 419
Query: 777 -QHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA 835
+ V ++ ALK F R+LP+ LF + ++ A +++D+ + R+L+ LP N
Sbjct: 420 WEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHD 479
Query: 836 TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQD 876
T++ L HL V + N+M+V ++AIVFGPTL + + ++
Sbjct: 480 TLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE 520
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 95.5 bits (236), Expect = 3e-19
Identities = 63/203 (31%), Positives = 100/203 (49%), Gaps = 26/203 (12%)
Query: 249 DRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALS------------------TS 290
+++ FDL + R + F A+ E E + W+ +Q + EAL+ T
Sbjct: 362 EKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTK 421
Query: 291 EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRK 350
E+ + N C DCGAP P W S NL ++ C C+G HR LG S+++SL +D
Sbjct: 422 EIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVL 481
Query: 351 VWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS--SSPSTRRCHLEAKYREGKY-RRY 407
+E L L +GN N +P ++++P+ S + R+ ++ AKY E +Y R+
Sbjct: 482 GTSELL--LAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKK 539
Query: 408 HPLFGNQEELDKALCAAVTTTDL 430
H N +L +LC AV T D+
Sbjct: 540 HA--DNAAKL-HSLCEAVKTRDI 559
Score = 32.3 bits (72), Expect = 2.8
Identities = 13/33 (39%), Positives = 23/33 (69%)
Query: 143 FEVITNNRTFAFRAESDVERKEWMQALQQAMAE 175
F++I+++RT+ F+AE + E + WM LQ + E
Sbjct: 366 FDLISHDRTYHFQAEDEQECQIWMSVLQNSKEE 398
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 95.5 bits (236), Expect = 3e-19
Identities = 63/203 (31%), Positives = 100/203 (49%), Gaps = 26/203 (12%)
Query: 249 DRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALS------------------TS 290
+++ FDL + R + F A+ E E + W+ +Q + EAL+ T
Sbjct: 362 EKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTK 421
Query: 291 EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRK 350
E+ + N C DCGAP P W S NL ++ C C+G HR LG S+++SL +D
Sbjct: 422 EIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVL 481
Query: 351 VWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS--SSPSTRRCHLEAKYREGKY-RRY 407
+E L L +GN N +P ++++P+ S + R+ ++ AKY E +Y R+
Sbjct: 482 GTSELL--LAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKK 539
Query: 408 HPLFGNQEELDKALCAAVTTTDL 430
H N +L +LC AV T D+
Sbjct: 540 HA--DNAAKL-HSLCEAVKTRDI 559
Score = 32.3 bits (72), Expect = 2.8
Identities = 13/33 (39%), Positives = 23/33 (69%)
Query: 143 FEVITNNRTFAFRAESDVERKEWMQALQQAMAE 175
F++I+++RT+ F+AE + E + WM LQ + E
Sbjct: 366 FDLISHDRTYHFQAEDEQECQIWMSVLQNSKEE 398
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 94.7 bits (234), Expect = 5e-19
Identities = 54/176 (30%), Positives = 90/176 (51%), Gaps = 20/176 (11%)
Query: 249 DRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALS-----------------TSE 291
D++SFDL + R + F A+ E + W+ + + EAL+ T
Sbjct: 381 DKKSFDLISHNRTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQSAGENSLEDLTKA 440
Query: 292 VAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV 351
+ E + N C DCG+ +P W S NL ++ C C+G HR +G +S+++SL++D+
Sbjct: 441 IIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLG 500
Query: 352 WTETLIELFLQLGNGAGNRFWAANVP-PSEALQPSSSPSTRRCHLEAKYREGKYRR 406
+E L L +GN + N AN+P PS PSS + R+ ++ AKY + ++ R
Sbjct: 501 TSELL--LAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHRFSR 554
Score = 32.7 bits (73), Expect = 2.1
Identities = 44/215 (20%), Positives = 82/215 (38%), Gaps = 26/215 (12%)
Query: 85 KAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFE 144
K G+L K ++Q+R + L + + + + C A + F+
Sbjct: 327 KKGYLLKKSDGIRKVWQRRKCSVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSFD 386
Query: 145 VITNNRTFAFRAESDVERKEWMQALQQAMAE-------------QRARARLSSAYLLGV- 190
+I++NRT+ F+AE + + W+ L + E + + L+ A + V
Sbjct: 387 LISHNRTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQSAGENSLEDLTKAIIEDVQ 446
Query: 191 --PGSEQPDRAGSLELRGFKNKLYVAV----------VGDKVQLYKNLEEYHLGIGITFI 238
PG++ GS E L + +G + ++LE LG +
Sbjct: 447 RLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLGTSELLL 506
Query: 239 DMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKE 273
+VGN D +L +P + S+D + KE
Sbjct: 507 AKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKE 541
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 94.7 bits (234), Expect = 5e-19
Identities = 60/198 (30%), Positives = 91/198 (45%), Gaps = 36/198 (18%)
Query: 241 SVGNVKEVDRR-SFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEA------------- 286
+V + ++++RR F++ +P + ADSE ++ W++A+Q +IA A
Sbjct: 317 TVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDK 376
Query: 287 -------------------LSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKR 327
L +R+ N C DCG P WASINL + +C
Sbjct: 377 KSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIE 436
Query: 328 CAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS-S 386
C+G HR LG SKVRSL +D W L++L +LGN NR + ANV +P
Sbjct: 437 CSGIHRSLGVHFSKVRSLTLD--TWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPG 494
Query: 387 SPSTRRCHLEAKYREGKY 404
+ ++ AKY E K+
Sbjct: 495 QRQEKEAYIRAKYVERKF 512
Score = 33.5 bits (75), Expect = 1.3
Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 83 VIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKD--AYSKRFISVACISHVAAIGD 140
++ G+L K + +RW + + L Y KD + + + H I
Sbjct: 267 IVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIER 326
Query: 141 QK-FEVITNNRTFAFRAESDVERKEWMQALQQAMA 174
+ FEV++ ++ +A+S+ R+ W++A+Q ++A
Sbjct: 327 RFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIA 361
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 94.7 bits (234), Expect = 5e-19
Identities = 86/304 (28%), Positives = 142/304 (46%), Gaps = 27/304 (8%)
Query: 636 EGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRL 695
+G+ SL G+++ + P GP E+P + L E+S G E + + L +R
Sbjct: 78 QGFISLQGTQVTEL-PPGP-EDPG--KHLFEISPGGAGEREKVPANPEALLLMASSQR-- 131
Query: 696 DFMGWLGAIQKAA-ASMGDTLSEQQL----------GDSDIPVIVYRCVDYITQCGLTSE 744
D W+ AI++ A +G + Q+L G P++V +CVD+I + GLT E
Sbjct: 132 DMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEE 191
Query: 745 GIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRL 804
G++R GQ + + L +S D L + V V+S LK +LR+LP+ + A+
Sbjct: 192 GLFRMPGQANLVRDLQDSF--DCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYE 249
Query: 805 TWLEASEI--EDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLA 862
+L +++ +DE E + + LP N ++ + L VQ +S+ N+M+V NLA
Sbjct: 250 DFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLA 309
Query: 863 IVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASG 922
VFGP + + +D L+ H + V +RK + TA V G
Sbjct: 310 TVFGPNILRPQVEDPVTIMEGTSLVQHLMTVL------IRKHSQLFTAPVPEGPTSPRGG 363
Query: 923 TQHA 926
Q A
Sbjct: 364 LQCA 367
Score = 38.9 bits (89), Expect = 0.030
Identities = 29/118 (24%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 511 AGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFE 570
AG L + R + + +RW VL L Y++++ + P G I +PP +
Sbjct: 41 AGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGK 100
Query: 571 HTFEVYT--EGER--------LYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFE 618
H FE+ GER L S +WV+ I + PL + + E
Sbjct: 101 HLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLE 158
Score = 35.0 bits (79), Expect = 0.43
Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 22/111 (19%)
Query: 82 PVIKAGWLDKNPPQGSYI--YQKRWVRLDTDHLRYFDSNKDAYSKRFISVACI------- 132
PV+KAGWL K Q S + +Q+RW L D L Y+ + + FIS+
Sbjct: 37 PVLKAGWLKK---QRSIMKNWQQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPP 93
Query: 133 ------SHVAAI----GDQKFEVITNNRTFAFRAESDVERKEWMQALQQAM 173
H+ I ++ +V N A S + ++W+QA+++ +
Sbjct: 94 GPEDPGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRRVI 144
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 92.4 bits (228), Expect = 2e-18
Identities = 65/225 (28%), Positives = 98/225 (43%), Gaps = 21/225 (9%)
Query: 264 FSADSELEKEQWLEAMQGAIAEALSTSEVA---------------ERIWAAAPNRFCADC 308
F A + E+E W++++Q I +L A + + N FC DC
Sbjct: 621 FEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDC 680
Query: 309 GAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAG 368
AP PDWAS+NL ++C C+G HR LGA +S+VRSL +D W L+ + +GN
Sbjct: 681 DAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDD--WPPELLAVMTAMGNALA 738
Query: 369 NRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTT 428
N W + P + + + AKY + + PL + L + L AV
Sbjct: 739 NSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLF--LAPLPSSDVPLGQQLLRAVVED 796
Query: 429 DLAETQALLGCGA--GINCFSGDPEAPTPLALAEQAGQTLQMEFL 471
DL LL G+ +N GD + T L L+ + + L
Sbjct: 797 DLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLL 841
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 92.4 bits (228), Expect = 2e-18
Identities = 64/196 (32%), Positives = 102/196 (52%), Gaps = 11/196 (5%)
Query: 725 IPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGE-QHVDDVS 783
IP+IV C + + GL GIYR G + + E L + + +++ + + ++ +S
Sbjct: 1161 IPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVIS 1220
Query: 784 SALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISH 843
S LK F R LP+ LFT + ++EA+ ED +++ + L+ LP + T+K L +H
Sbjct: 1221 SLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLSAH 1280
Query: 844 LYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDY--------KAGRVVEDLINHYVVVFS 895
L V S+ N+M NLAIVFGPTL +T + ++VE LI H+ F+
Sbjct: 1281 LKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFT 1340
Query: 896 VD--EEELRKQREEIT 909
+ EE L +EE T
Sbjct: 1341 EEGAEEPLTTVQEEST 1356
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 91.7 bits (226), Expect = 4e-18
Identities = 53/186 (28%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Query: 722 DSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGE-QHVD 780
+S +P V +C++ + + GL +GIYR G + Q+L + Q+ + ++L + + + +
Sbjct: 291 NSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEK-LNLDDSQWEDIH 349
Query: 781 DVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKAL 840
V+ ALK F R+LP+ LF + ++EA + +D ++ + L+ +LPP NR T+K L
Sbjct: 350 VVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVL 409
Query: 841 ISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQD-------YKAGRVVEDLINHYVVV 893
HL + + N M+ +L IVFGPTL + + + ++ E +++ Y +
Sbjct: 410 FGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSEYSKI 469
Query: 894 FSVDEE 899
F +E+
Sbjct: 470 FGSEED 475
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 90.9 bits (224), Expect = 7e-18
Identities = 75/236 (31%), Positives = 105/236 (44%), Gaps = 42/236 (17%)
Query: 725 IPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSS 784
+P IV +CV I + L ++GIYR G ++ ++L ++ V L + H D+S+
Sbjct: 774 VPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPH--DISN 831
Query: 785 ALKRFLRDLPDGL--FTRAQRLTWLEASEIEDEEEK--------------------VSRY 822
LK +LR LP+ L F L L ++ E E R
Sbjct: 832 VLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRL 891
Query: 823 RELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQ----------T 872
RELL LPP NRA+++ L+ HL + N+M NL IVFGPTL + +
Sbjct: 892 RELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLS 951
Query: 873 DGQDY-KAGRVVEDLINHYVVVFSVDEEEL-------RKQREEITAIVKMRVAGTA 920
DY RV+E LI HY +VF + EE QR E+ V AG A
Sbjct: 952 SLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEA 1007
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 90.9 bits (224), Expect = 7e-18
Identities = 54/162 (33%), Positives = 85/162 (52%), Gaps = 1/162 (0%)
Query: 712 GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVH 771
G L + + IP+ V +CV++I GL +EG+YR G + + + QD +++
Sbjct: 1261 GMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQD-HNIN 1319
Query: 772 LKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPP 831
L E V+ V+ ALK F DLPD L + LEA++I D+ E++ +E++ + P
Sbjct: 1320 LVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHP 1379
Query: 832 VNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD 873
VN + +I+HL V N M NL+I F PTL + D
Sbjct: 1380 VNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPD 1421
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 90.9 bits (224), Expect = 7e-18
Identities = 54/162 (33%), Positives = 85/162 (52%), Gaps = 1/162 (0%)
Query: 712 GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVH 771
G L + + IP+ V +CV++I GL +EG+YR G + + + QD +++
Sbjct: 1260 GMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQD-HNIN 1318
Query: 772 LKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPP 831
L E V+ V+ ALK F DLPD L + LEA++I D+ E++ +E++ + P
Sbjct: 1319 LVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHP 1378
Query: 832 VNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD 873
VN + +I+HL V N M NL+I F PTL + D
Sbjct: 1379 VNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPD 1420
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 90.5 bits (223), Expect = 9e-18
Identities = 62/186 (33%), Positives = 90/186 (48%), Gaps = 30/186 (16%)
Query: 249 DRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERI-----WAAAP-- 301
+++ FDL T R + F A+ E E E W+ +Q + EALS++ + E W +A
Sbjct: 350 EKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHD 409
Query: 302 -------------------NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKV 342
N C DCGA P W S NL V+ C +C+G HR LG S++
Sbjct: 410 GEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRM 469
Query: 343 RSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS--SSPSTRRCHLEAKYR 400
+SL +D +E L L L +GN + N A +P +PS S TRR ++ AKY
Sbjct: 470 QSLTLDLLGPSELL--LALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYV 527
Query: 401 EGKYRR 406
E ++ R
Sbjct: 528 EHRFAR 533
Score = 36.2 bits (82), Expect = 0.19
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 5/45 (11%)
Query: 143 FEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYL 187
F+++T+NRT+ F+AE + E + W+ LQ + E LSSA+L
Sbjct: 354 FDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDE-----ALSSAFL 393
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 90.5 bits (223), Expect = 9e-18
Identities = 62/186 (33%), Positives = 90/186 (48%), Gaps = 30/186 (16%)
Query: 249 DRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERI-----WAAAP-- 301
+++ FDL T R + F A+ E E E W+ +Q + EALS++ + E W +A
Sbjct: 359 EKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHD 418
Query: 302 -------------------NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKV 342
N C DCGA P W S NL V+ C +C+G HR LG S++
Sbjct: 419 GEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRM 478
Query: 343 RSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS--SSPSTRRCHLEAKYR 400
+SL +D +E L L L +GN + N A +P +PS S TRR ++ AKY
Sbjct: 479 QSLTLDLLGPSELL--LALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYV 536
Query: 401 EGKYRR 406
E ++ R
Sbjct: 537 EHRFAR 542
Score = 36.2 bits (82), Expect = 0.19
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 5/45 (11%)
Query: 143 FEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYL 187
F+++T+NRT+ F+AE + E + W+ LQ + E LSSA+L
Sbjct: 363 FDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDE-----ALSSAFL 402
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 90.5 bits (223), Expect = 9e-18
Identities = 60/192 (31%), Positives = 96/192 (50%), Gaps = 8/192 (4%)
Query: 715 LSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKE 774
L Q L ++ IP +V+ V+Y+TQ GLT EG++R G ++L K+
Sbjct: 48 LERQGLTENGIPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKD 107
Query: 775 GEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNR 834
G+ V +S LK FLR+LPD L T A + +++ + + + S R+L+ LP +
Sbjct: 108 GD--VCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPDTHY 165
Query: 835 ATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQT----DGQDYK--AGRVVEDLIN 888
+K L L V N+MNVHNLA VFGP F +G + +++ ++
Sbjct: 166 CLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQDLCNKIMAKILE 225
Query: 889 HYVVVFSVDEEE 900
+Y +F V+ E
Sbjct: 226 NYNTLFEVEYTE 237
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 88.2 bits (217), Expect = 4e-17
Identities = 64/230 (27%), Positives = 111/230 (48%), Gaps = 16/230 (6%)
Query: 681 VERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVI----VYRCVDYI 736
V+R + +Q D W+ A+ Q G + + I + +C+ +
Sbjct: 341 VDRPGVITMQALSEEDRRLWMEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAV 400
Query: 737 TQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKE----GEQHVDDVSSALKRFLRD 792
G+ +G+YR G S+ Q+LL S+ D ++ E E + ++SALK +LR
Sbjct: 401 ETRGINEQGLYRIVGVNSRVQKLL-SVLMDPKTASETETDICAEWEIKTITSALKTYLRM 459
Query: 793 LPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSD 852
LP L + ++++A+++E++E +VS L+ RLP NR ++ L++HL V
Sbjct: 460 LPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHK 519
Query: 853 TNQMNVHNLAIVFGPTLFQTDGQDYKA-------GRVVEDLINHYVVVFS 895
N M V NL +VFGPTL + + A V+E LI ++ +F+
Sbjct: 520 QNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFN 569
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,956,442
Number of Sequences: 37866
Number of extensions: 2367510
Number of successful extensions: 7801
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 7186
Number of HSP's gapped (non-prelim): 505
length of query: 1205
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1091
effective length of database: 13,930,794
effective search space: 15198496254
effective search space used: 15198496254
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.