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Search of human proteins with 205277354
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
(3538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 7475 0.0
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 6449 0.0
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 6449 0.0
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 4835 0.0
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 4326 0.0
gi|148886654 polydom [Homo sapiens] 474 e-133
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 401 e-111
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 397 e-109
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 333 2e-90
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 315 7e-85
gi|157419154 selectin P precursor [Homo sapiens] 242 5e-63
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 233 2e-60
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 233 3e-60
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 233 3e-60
gi|22547221 tolloid-like 1 [Homo sapiens] 218 8e-56
gi|6912724 tolloid-like 2 [Homo sapiens] 213 2e-54
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 212 5e-54
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 212 5e-54
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 208 9e-53
gi|187960042 selectin E precursor [Homo sapiens] 206 3e-52
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 199 5e-50
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 197 1e-49
gi|4502503 complement component 4 binding protein, alpha chain p... 196 3e-49
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 192 6e-48
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 186 3e-46
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 146 3e-34
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 145 5e-34
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 134 2e-30
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 129 5e-29
gi|13899255 membrane frizzled-related protein [Homo sapiens] 125 1e-27
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 7475 bits (19394), Expect = 0.0
Identities = 3538/3538 (100%), Positives = 3538/3538 (100%)
Query: 1 MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG 60
MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG
Sbjct: 1 MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG 60
Query: 61 FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS
Sbjct: 61 FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA
Sbjct: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
Query: 301 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPG 360
EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPG
Sbjct: 301 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPG 360
Query: 361 KDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSI 420
KDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSI
Sbjct: 361 KDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSI 420
Query: 421 TCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTN 480
TCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTN
Sbjct: 421 TCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTN 480
Query: 481 KVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTD 540
KVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTD
Sbjct: 481 KVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTD 540
Query: 541 ESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC 600
ESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC
Sbjct: 541 ESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC 600
Query: 601 QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN 660
QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN
Sbjct: 601 QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN 660
Query: 661 DFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNI 720
DFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNI
Sbjct: 661 DFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNI 720
Query: 721 TYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMW 780
TYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMW
Sbjct: 721 TYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMW 780
Query: 781 SGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTEL 840
SGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTEL
Sbjct: 781 SGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTEL 840
Query: 841 NYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 900
NYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT
Sbjct: 841 NYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 900
Query: 901 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 960
VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD
Sbjct: 901 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 960
Query: 961 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1020
ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT
Sbjct: 961 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1020
Query: 1021 ENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCED 1080
ENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCED
Sbjct: 1021 ENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCED 1080
Query: 1081 PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGAS 1140
PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGAS
Sbjct: 1081 PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGAS 1140
Query: 1141 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1200
ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT
Sbjct: 1141 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1200
Query: 1201 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGY 1260
HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGY
Sbjct: 1201 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGY 1260
Query: 1261 KISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSG 1320
KISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSG
Sbjct: 1261 KISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSG 1320
Query: 1321 RILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKE 1380
RILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKE
Sbjct: 1321 RILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKE 1380
Query: 1381 ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR 1440
ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR
Sbjct: 1381 ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR 1440
Query: 1441 EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNF 1500
EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNF
Sbjct: 1441 EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNF 1500
Query: 1501 PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLP 1560
PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLP
Sbjct: 1501 PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLP 1560
Query: 1561 ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVT 1620
ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVT
Sbjct: 1561 ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVT 1620
Query: 1621 YYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV 1680
YYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV
Sbjct: 1621 YYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV 1680
Query: 1681 GHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSS 1740
GHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSS
Sbjct: 1681 GHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSS 1740
Query: 1741 GNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDC 1800
GNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDC
Sbjct: 1741 GNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDC 1800
Query: 1801 NPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLN 1860
NPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLN
Sbjct: 1801 NPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLN 1860
Query: 1861 CVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNN 1920
CVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNN
Sbjct: 1861 CVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNN 1920
Query: 1921 LYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 1980
LYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL
Sbjct: 1921 LYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 1980
Query: 1981 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP
Sbjct: 1981 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
Query: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2100
IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD
Sbjct: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2100
Query: 2101 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC 2160
YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC
Sbjct: 2101 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC 2160
Query: 2161 LHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN 2220
LHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN
Sbjct: 2161 LHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN 2220
Query: 2221 FTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFV 2280
FTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFV
Sbjct: 2221 FTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFV 2280
Query: 2281 LSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ 2340
LSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ
Sbjct: 2281 LSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ 2340
Query: 2341 MDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2400
MDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ
Sbjct: 2341 MDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2400
Query: 2401 TEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
TEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY
Sbjct: 2401 TEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
Query: 2461 IAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPV 2520
IAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPV
Sbjct: 2461 IAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPV 2520
Query: 2521 PACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2580
PACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN
Sbjct: 2521 PACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2580
Query: 2581 KTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESE 2640
KTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESE
Sbjct: 2581 KTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESE 2640
Query: 2641 TRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2700
TRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS
Sbjct: 2641 TRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2700
Query: 2701 CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2760
CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK
Sbjct: 2701 CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2760
Query: 2761 VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2820
VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE
Sbjct: 2761 VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2820
Query: 2821 CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS 2880
CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS
Sbjct: 2821 CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS 2880
Query: 2881 GDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 2940
GDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC
Sbjct: 2881 GDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 2940
Query: 2941 KAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3000
KAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT
Sbjct: 2941 KAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3000
Query: 3001 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR 3060
IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR
Sbjct: 3001 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR 3060
Query: 3061 AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPK 3120
AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPK
Sbjct: 3061 AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPK 3120
Query: 3121 FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3180
FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ
Sbjct: 3121 FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3180
Query: 3181 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 3240
TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH
Sbjct: 3181 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 3240
Query: 3241 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3300
SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG
Sbjct: 3241 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3300
Query: 3301 SKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVN 3360
SKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVN
Sbjct: 3301 SKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVN 3360
Query: 3361 ATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGAT 3420
ATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGAT
Sbjct: 3361 ATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGAT 3420
Query: 3421 YVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGF 3480
YVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGF
Sbjct: 3421 YVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGF 3480
Query: 3481 YLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
YLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV
Sbjct: 3481 YLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 6449 bits (16731), Expect = 0.0
Identities = 3083/3268 (94%), Positives = 3110/3268 (95%), Gaps = 77/3268 (2%)
Query: 342 YQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 401
++VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG
Sbjct: 406 HRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 465
Query: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP
Sbjct: 466 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 525
Query: 462 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 521
FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF
Sbjct: 526 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 585
Query: 522 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 581
VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV
Sbjct: 586 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 645
Query: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 641
LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL
Sbjct: 646 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 705
Query: 642 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 701
NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH
Sbjct: 706 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 765
Query: 702 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 761
ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI
Sbjct: 766 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 825
Query: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 821
KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI
Sbjct: 826 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 885
Query: 822 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 881
EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF
Sbjct: 886 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 945
Query: 882 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 941
TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE
Sbjct: 946 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 1005
Query: 942 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV
Sbjct: 1006 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
Query: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1061
QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI
Sbjct: 1066 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1125
Query: 1062 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1121
SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG
Sbjct: 1126 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1185
Query: 1122 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1181
GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART
Sbjct: 1186 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1245
Query: 1182 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1241
FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV
Sbjct: 1246 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1305
Query: 1242 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1301
YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY
Sbjct: 1306 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
Query: 1302 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1361
PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS
Sbjct: 1366 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1425
Query: 1362 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1421
HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA
Sbjct: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485
Query: 1422 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1481
TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI
Sbjct: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY
Sbjct: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
Query: 1542 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1601
DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG
Sbjct: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1665
Query: 1602 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1661
NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR
Sbjct: 1666 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1725
Query: 1662 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1721
STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS
Sbjct: 1726 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1785
Query: 1722 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1781
SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR
Sbjct: 1786 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1845
Query: 1782 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1841
FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK
Sbjct: 1846 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1905
Query: 1842 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1901
RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR
Sbjct: 1906 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1965
Query: 1902 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 1961
LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG
Sbjct: 1966 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 2025
Query: 1962 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2021
DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP
Sbjct: 2026 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2085
Query: 2022 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2081
GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ
Sbjct: 2086 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2145
Query: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT 2141
IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT
Sbjct: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT 2205
Query: 2142 ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN 2201
ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN
Sbjct: 2206 ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN 2265
Query: 2202 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2261
FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST
Sbjct: 2266 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2325
Query: 2262 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2321
SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP
Sbjct: 2326 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2385
Query: 2322 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA 2381
GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA
Sbjct: 2386 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA 2445
Query: 2382 WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV 2441
WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV
Sbjct: 2446 WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV 2505
Query: 2442 FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK 2501
FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK
Sbjct: 2506 FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK 2565
Query: 2502 SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLS 2561
SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLS
Sbjct: 2566 SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLS 2625
Query: 2562 SKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKI-----------GTQTSYGS 2610
SKELTTAVCQSDGTWSNHNKTPRCVV++C P+ N G+ Y +
Sbjct: 2626 SKELTTAVCQSDGTWSNHNKTPRCVVVTC------PSINSFILEHGRWRIVNGSHYEYKT 2679
Query: 2611 TAIFTCDLGFMLVGSAVRECLSSGLWSESETR--CLAGHCGIPELIVNGQVIGENYGYRD 2668
+F+CD G+ +G A ECL +G WS R C CG NG IG Y
Sbjct: 2680 KVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS 2739
Query: 2669 TVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVV 2728
T ++ C+ GF L+GS+VR C WS C+ CG P + G+ G + + D V
Sbjct: 2740 TAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTV 2799
Query: 2729 TFSCNIGYLMQGPTKAQCQANRQWS------------HP--------------------- 2755
+ CN G+ + G + CQ + WS HP
Sbjct: 2800 VYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTF 2859
Query: 2756 ------------------------PP-MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2790
PP MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV
Sbjct: 2860 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2919
Query: 2791 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY 2850
FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY
Sbjct: 2920 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY 2979
Query: 2851 SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVR 2910
SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVR
Sbjct: 2980 SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVR 3039
Query: 2911 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 2970
YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY
Sbjct: 3040 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 3099
Query: 2971 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3030
SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC
Sbjct: 3100 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3159
Query: 3031 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYIC 3090
QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYIC
Sbjct: 3160 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYIC 3219
Query: 3091 SPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNF 3150
SPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNF
Sbjct: 3220 SPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNF 3279
Query: 3151 PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC 3210
PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC
Sbjct: 3280 PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC 3339
Query: 3211 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ 3270
KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ
Sbjct: 3340 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ 3399
Query: 3271 PGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3330
PGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY
Sbjct: 3400 PGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3459
Query: 3331 IWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLI 3390
IWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLI
Sbjct: 3460 IWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLI 3519
Query: 3391 KVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNS 3450
KVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNS
Sbjct: 3520 KVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNS 3579
Query: 3451 SNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFEN 3510
SNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFEN
Sbjct: 3580 SNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFEN 3639
Query: 3511 PMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
PMYDTNAKSVEGKAVRFDPNLNTVCTMV
Sbjct: 3640 PMYDTNAKSVEGKAVRFDPNLNTVCTMV 3667
Score = 1778 bits (4605), Expect = 0.0
Identities = 1062/3097 (34%), Positives = 1543/3097 (49%), Gaps = 187/3097 (6%)
Query: 175 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
S+ C +PG P G G+ F +G +++SC Y+L G +TC + A+W P+
Sbjct: 443 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
Query: 235 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVA-EPGDTISLIFTDFQMEEKYD 293
C+ + CG ++G SG +SP+FP +Y +NA C W I A I + F +F +E YD
Sbjct: 503 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
Query: 294 YLEI----EGSEPPTIW--LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKA 347
L I E +P T+ L+G +P I+S + + LH TD + GF Y K
Sbjct: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 618
Query: 348 IDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFS 407
I+ +S C DPG P G R G FS ++F
Sbjct: 619 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDVLRFE 649
Query: 408 CDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSN 467
C + L G KSI CQ + WS + P+C + C SN P GT SP++P Y +N
Sbjct: 650 CQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNN 704
Query: 468 AQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIV 527
C+W I + + I ++F +FDLE +D L + DG P +L TG+ VP +
Sbjct: 705 LNCIWTIIS-DPGSRIHLSFNDFDLESQFDFLAVKDGDSPESP--ILGTFTGAEVPSHLT 761
Query: 528 SMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQ 587
S S + L Q D S+ GF + Y C DPG P+ R GD F + C+
Sbjct: 762 SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICE 821
Query: 588 FGF-ELIGEKSIVC---QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
GF + G ++I C WS IP C PC +F+AP G +LSP +P Y ++LNC
Sbjct: 822 EGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNC 881
Query: 644 IWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
W I ++PG I ++F F E +D L V DG + SP+LG++ G +VP L S+S+ +
Sbjct: 882 EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI 941
Query: 704 RLEFQADHSMSGRGFNITYNTFGHN--ECPDPGIPINARRFGDNFQLGSSISVICEEGFI 761
L F D+S S GF I Y + N C DPGIP++ RR+G +F +GS++S C+ G+
Sbjct: 942 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGY- 1000
Query: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 821
+ E + C + WS +P C A CGG PSG ILSPG+P +Y +SLNC W +
Sbjct: 1001 RLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTV 1057
Query: 822 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSS--SNF-IY 878
+ G ++ F F E ++D L + + + P L G+ +P + + NF
Sbjct: 1058 DVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQ 1116
Query: 879 LLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRL 938
L F +D S S GF I + N C DPGIP +G R G +F IG T++FSC SGYRL
Sbjct: 1117 LRFISDFSISYEGFNITFSE--YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRL 1174
Query: 939 SHEEPLLC--EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVT 996
++C WS PLP C A CG G +LSP YP Y N+ C +++ V
Sbjct: 1175 EGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQ 1234
Query: 997 HGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI 1056
GKG+ + TFHL + T L TG+ + + + + L F
Sbjct: 1235 AGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSST--SNQLWLEFN 1292
Query: 1057 SDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIG-FNFGIGDTLTFSCSSGYRLEGTSE 1115
SD + EGF + ++ + L CEDPGIPQ+G +I G T+ + C+ GY L G+S
Sbjct: 1293 SDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSL 1352
Query: 1116 IICLGGGRRVWSAPLPRCVAECGAS-ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKG 1174
+ C+ G RR W PLP C+AECG + G +LSP YP Y+NN C++ I+V G
Sbjct: 1353 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1412
Query: 1175 INISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1233
+++ F A D+L+++DG + LL +G S+ + ST N + ++F++D
Sbjct: 1413 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISG-SLIPEGIHSTLNIVTIQFDTDFYI 1471
Query: 1234 TDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMT 1293
+ GF + ++S + C DPG+P G + D G G T+++ C+PGY L G + C+
Sbjct: 1472 SKSGFAIQFSSSVATACRDPGVPMNGTRNGD-GREPGDTVVFQCDPGYELQGEERITCIQ 1530
Query: 1294 GERR-AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQ 1352
E R W P CIA CGG G SSG ILSP +P PY ++ C W I V+ ++SL
Sbjct: 1531 VENRYFWQPSPPVCIAPCGGNLTG-SSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1589
Query: 1353 FLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGF 1412
F++F E ++D L ++DGP N L+ S +PE I S+ N + + F +D +S +GF
Sbjct: 1590 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1649
Query: 1413 AIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVEN-RY 1471
+++ + + +C DPG MNGTR G + G TV + CD GY LQG +TCI ++ R
Sbjct: 1650 HLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRP 1709
Query: 1472 FWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSI 1531
W + P C APCG TGS G +LSPN+P Y +C ++I V ++V+ F+ F
Sbjct: 1710 GWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT 1769
Query: 1532 EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE-SSSNTMHLAFRSDGSVSYTGFHLEYK 1590
+D + +YDGP S L+ S S E + SS N + + F S G ++ GFH Y+
Sbjct: 1770 S-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQ 1828
Query: 1591 AKLRES---CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGW 1647
A R S C G R+G ++ +GS+V + C+ GY+L G + C + W
Sbjct: 1829 AVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQW 1888
Query: 1648 NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL 1707
N +LP+C PCG T +GT+LSP YP+ Y NCV+ I VP+ + Q V F T
Sbjct: 1889 NDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEH 1948
Query: 1708 H-DVVEVYDGPTQQSSLLSSLSGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHFVY 1763
+ D ++ YDG + L GS+SG ++P S+ N + + F S ++A GFH Y
Sbjct: 1949 NWDSLDFYDGGDNNAPRL----GSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2004
Query: 1764 QAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
A+ S C P G +IG+ + VG V F C+ GY L G I C +P + +
Sbjct: 2005 TAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC--MPGPVRR 2059
Query: 1824 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1883
WN +P C+ CGG ++ G ILSPG+P Y ++L+C W I +P G G+ +Q V+F+TE
Sbjct: 2060 WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE 2119
Query: 1884 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
D L+ G + +G SG IP L ST++ L F SD S + GFH+ Y A
Sbjct: 2120 TIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAY 2179
Query: 1944 GLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
L SCP+P+ +G IG+ + VG +SF+C GY+L G+S +TC+ G R WN+P+P C
Sbjct: 2180 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2239
Query: 2004 LAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
A CGG ++ +G I SPG+P YP+ DC W + +P G G+++ F TE I+D++ V
Sbjct: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITV 2299
Query: 2064 RSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIV-YQAYQLQSCPD 2122
G + S IG+ SG S++ST+++ + FHSD++ + GF ++ Y AYQL+ C
Sbjct: 2300 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2357
Query: 2123 PRPFRNGFVIGND--FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
P P N ++ D F +G I ++C PG+TL+GN+ LTC G + P C+ LC
Sbjct: 2358 PPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCP 2417
Query: 2181 GNITAMN--GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238
N ++ G I SPGYPD YPN Q C W + V G I + QTE +D + V+DG
Sbjct: 2418 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2477
Query: 2239 PDQNSPQIGQFSGN-TALESVYSTSNQILIKFHSDF-TTSGFFVLSYHAYQLRVCQPPPP 2296
P+ SP + SG+ ++ ++ S +++ +++ +D F + Y A+ C P
Sbjct: 2478 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPES 2534
Query: 2297 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE--RLQMDGAPPVCQVLCPA 2354
P+ I+++ ++ ++R+ C GF LVG + CR D P CQ +
Sbjct: 2535 PPHGYIISQTGG-QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SC 2592
Query: 2355 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVE---FFQTEKEFDVLQVY 2411
+ + G IL+ Y C + T + + + V
Sbjct: 2593 GIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVV 2652
Query: 2412 DGPNIQSPVLISLSGDYSSAFNITSNGHEVF---LQWSADHGNNKKG-----------FR 2457
P+I S +L + I + H + + +S D G + G +
Sbjct: 2653 TCPSINSFIL------EHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2706
Query: 2458 IRYIAFYCSTPE-----SPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2512
R YC +PP+G I T S + CD GF LVG + C S
Sbjct: 2707 WRNERPYCQIISCGELPTPPNGNKIG-TQTSYGSTAIFTCDLGFMLVGSAVRECLSSG-- 2763
Query: 2513 YHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQS 2572
W C A CGIP+ NG ++ +Y V Y CN G+RL + +CQ
Sbjct: 2764 --LWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS--SVRICQQ 2819
Query: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLS 2632
D WS + P CV +SCG +P G G ++ F+C++G+++ G +C +
Sbjct: 2820 DHNWS--GQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2877
Query: 2633 SGLWSESETRCLAGHCGIPELIVN----GQVIGENYGYRDTVVYQCNPGFRLIGSSVRIC 2688
+ WS C +C P + N ++ N+ Y V Y CNPG+ L GSSV IC
Sbjct: 2878 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2937
Query: 2689 QQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2748
Q + W LP C+ + CGHPG P SG + F V +SC + G + CQ
Sbjct: 2938 QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQL 2997
Query: 2749 NRQWSHPPPMCK---VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSV 2805
N WS P C C DPG P + R + NF + V Y C+ GY L GS
Sbjct: 2998 NGHWSGSQPHCSGDATGTCGDPGTPGHGSR----QESNFRTKSTVRYACDTGYILHGSEE 3053
Query: 2806 LICQPNGQWDKPLPECIMIDCGHPGVPPNA-VLSGEKYTFGSTVHYSCTGKRSLLGQSSR 2864
C NG W PEC + CG+PG N V + TF S+V YSC L G S R
Sbjct: 3054 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 3113
Query: 2865 TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYI--LHGS 2922
C NG WSG+ P+C+ +CGDPG P +G R ++ V Y C GY L+GS
Sbjct: 3114 QCTANGTWSGTLPNCT---IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3170
Query: 2923 EERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF--SSSVIYSCMEGYILSG 2980
RTC NG+W+G P C+AV C P +NG R++GT F S+ Y C GY LS
Sbjct: 3171 RIRTCTINGTWSGVMPTCRAVTCPTPPQISNG---RLEGTNFDWGFSISYICSPGYELSF 3227
Query: 2981 PSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNG 3040
P+V C NGTWSG +P C CGDPGIPA G R G ++ VS+ C + L G
Sbjct: 3228 PAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSC--NFPFILVG 3285
Query: 3041 SRIRTCTINGTWSGVMPTC---RAVTCPTPPQISNGRLEGT-NFDWGFSISYICSPGYEL 3096
S R C +GTWSG P C +C P +G T F G + + C G+ L
Sbjct: 3286 SSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL 3345
Query: 3097 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK-------REGKSFIYQSEVSFSCN 3149
TC+ + TWSG P+C+P C P PA G + IY + F
Sbjct: 3346 QGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGF--- 3402
Query: 3150 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENP 3186
F+ G+ R+C++D TW+G P C ++ ++P
Sbjct: 3403 --FLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
Score = 1280 bits (3312), Expect = 0.0
Identities = 783/2181 (35%), Positives = 1137/2181 (52%), Gaps = 124/2181 (5%)
Query: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLS 120
+ TCG L+G +GT SP FP+ Y + A C WVI A N+ IQI F+ F LE YD L+
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
Query: 121 LYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
+ DG P LTG +P + S S L L +D +V + GFKV Y+E++ SC
Sbjct: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
Query: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
G+PG P G+ G F D +R+ C G+ L G + C N+ W +PIC
Sbjct: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN----QWSANIPICIF- 679
Query: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
C G + SP +P Y NN +C WTI+++PG I L F DF +E ++D+L ++
Sbjct: 680 -PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 738
Query: 299 GSEPPTI----WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRG 354
+ P +G +P + SN + LRL F D + RGF+ Y
Sbjct: 739 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY------------ 786
Query: 355 FKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV- 413
N F N CPDPG P N +R G +F LGS++ C+E ++
Sbjct: 787 ----------NTF----------GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIK 826
Query: 414 LQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWV 473
QG ++ITC + + WS P C CG + PSG SP +P Y + C WV
Sbjct: 827 TQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCEWV 884
Query: 474 ITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQM 533
I A I+I FE F E+ YD L + DG + P +L G+ VP + S S+ +
Sbjct: 885 IEA-EPGHSIKITFERFQTELNYDVLEVHDGPNLLSP--LLGSYNGTQVPQFLFSSSNFI 941
Query: 534 WLHLQTDESVGSVGFKVNYKE--IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 591
+L TD S + GFK++Y+ + SC DPG P++G R G FS + F C G+
Sbjct: 942 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYR 1001
Query: 592 LIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDP 651
L E+ ++C++N+ WS +P C C + P GT+LSP YPE Y N+LNC WT+
Sbjct: 1002 LSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH 1061
Query: 652 GSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTS---NSHILRLEFQ 708
G + +F+ F LE D+L + + S P L TG+++P + + + +L F
Sbjct: 1062 GKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFI 1120
Query: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTET 768
+D S+S GFNIT++ + C DPGIP R G NF +G +++ C G+ + +GT
Sbjct: 1121 SDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGTSE 1179
Query: 769 ITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
I C L G+ +WS +P+C A CG + G++LSP +P Y+++ C + I+ + G
Sbjct: 1180 IIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKG 1238
Query: 829 IKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQF-LFSSSNFIYLLFTTDNSR 887
I I+ F DVL+++DG + + LLG++ G + L S+SN ++L F +D
Sbjct: 1239 INISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1297
Query: 888 SNNGFKIHYESVTVNTYSCLDPGIPVHGRR---YGHDFSIGSTVSFSCDSGYRLSHEEPL 944
++ GF++ Y S ++ C DPGIP G + GH GST+ + C+ GY L L
Sbjct: 1298 TDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGH--FAGSTIIYGCNPGYTLHGSSLL 1353
Query: 945 LC--EKNHWWSHPLPTCDALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
C + W +PLP+C A CGG +G SG ILSPGYP Y N+L C W ++V G V
Sbjct: 1354 KCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIV 1413
Query: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPLAR-LTGSDLPPTINAGLYGNFRAQLRFISDFS 1060
F F E HD L + + L + ++GS +P I++ L ++F +DF
Sbjct: 1414 SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFDTDFY 1470
Query: 1061 ISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1120
IS GF I FS C DPG+P G+R G GDT+ F C GY L+G I C+
Sbjct: 1471 ISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQ 1530
Query: 1121 -GGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISA 1179
R W P C+A CG + T + G +LSPN+P Y ++ +C ++I V A I+++
Sbjct: 1531 VENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAF 1590
Query: 1180 RTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGF 1238
+F + D L IYDG D + L+G+F + + + S+SN + L F SD + GF
Sbjct: 1591 ISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVSYTGF 1649
Query: 1239 QLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGE--R 1296
L Y + C DPG G ++ + GST+ Y C+ GY L G S L C+ G+ R
Sbjct: 1650 HLEYKAKLRESCFDPGNIMNGTRLG-MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGR 1708
Query: 1297 RAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAF 1356
W+ LPSC A CG R G S G +LSP YP Y C++ I V +V QF+ F
Sbjct: 1709 PGWNRALPSCHAPCGSRSTG-SEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFF 1767
Query: 1357 DTEASHDILRVWDGPPENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQ 1415
T + HD++ V+DGP + LL +SGS E + S+ N +TI+F + I+ GF
Sbjct: 1768 QT-SLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFV 1826
Query: 1416 FSS---SVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF 1472
+ + + +T C P G R G+ G +V+F C+PGY L G I C V N
Sbjct: 1827 YQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLA 1886
Query: 1473 -WQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSI 1531
W S P CI PCGG LT G ILSP +P PY ++ +C W ITV I + +SF+
Sbjct: 1887 QWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFAT 1946
Query: 1532 EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
E N+D L YDG D+N+P +GS+ + +P + S+SN ++L F+SD SVS GFHLEY A
Sbjct: 1947 EHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2006
Query: 1592 KLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1651
+SC +P +G ++G Y +G V++ CD GY LQG+S +TC+ G R WN +
Sbjct: 2007 IGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYPI 2064
Query: 1652 PSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT-SLHDV 1710
P C A CG + G +LSP +P NY +C ++I +P F V QFV F T ++HD
Sbjct: 2065 PICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDY 2124
Query: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
+EV G ++ S+++ LSG SL S+ ++ ++ F S +GFH VYQA
Sbjct: 2125 LEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY---- 2179
Query: 1771 STQCSSVPEPRFGRR---IGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1827
Q S P+PR R IGN+F VG ++ F+C PGY L G+ A+ C + WN
Sbjct: 2180 --QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNHP 2235
Query: 1828 LPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWD 1887
LP C CGG +T GTI SPGYP+ Y N +C W + VP G GI + TE +D
Sbjct: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD 2295
Query: 1888 SLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDS 1947
+ +DG D N+P++G +SG T + STSN + + F SD + S F L Y A L
Sbjct: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLRV 2354
Query: 1948 C-PEPQTPSSGIKI-GDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
C P P P++ I D + +GD++ +QC G++L G++ +TC G + + P+C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Query: 2006 QC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
C D +GVILSPG+P +YP+ C W+I++ G+ + + F TE D L+V
Sbjct: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
Query: 2064 RSGSSETSTVIGRLSGPQIPSSLFSTT---HETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
G + S V+ LSG SS F+ T HE L + +D+ NK+GF I Y A+ C
Sbjct: 2475 YDGPNIQSPVLISLSGDY--SSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---C 2529
Query: 2121 PDPRPFRNGFVIGNDFTVGQ---TISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRC 2175
P +G++I T GQ + + C G+ L+G S+ C W+ P+P C
Sbjct: 2530 STPESPPHGYIISQ--TGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
Query: 2176 EAL-CGGNITAMNGTIYSPGY 2195
+A+ CG NG I + Y
Sbjct: 2588 QAISCGIPKAPTNGGILTTDY 2608
Score = 1077 bits (2786), Expect = 0.0
Identities = 859/2907 (29%), Positives = 1253/2907 (43%), Gaps = 325/2907 (11%)
Query: 614 IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 673
I+ C GT+ SP +P GY N NC W II++ +RI + F F LE ++D+L++
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
Query: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 733
DG + TG +P +TS + L +D ++S GF + Y + C +P
Sbjct: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMD-GKVMWSGLIPKCGA--P 790
G+P +G F +G I C G+I G +TCI W +P C A
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
Query: 791 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 850
CGG SG+I SP +P Y ++ +C W I AEPG +I + F FQ E YD LE+
Sbjct: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 260
Query: 851 PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 910
P +G +P + S+ N++ L F TD++ GF Y+ + T++
Sbjct: 261 ----EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 316
Query: 911 IPVHGRRYGHDFSIGST------VSFSCDSGYRLSHEEPL-LCEKNHWWSHPLPTCDALC 963
+ H R ++ ST S + + +RLS E+ + + + P + D L
Sbjct: 317 LEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLS 376
Query: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH--GKGVQFNFHTFHL----EDHHDYL 1017
P+ T + P VTH K + F F L ++ + +
Sbjct: 377 ----PHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFS 432
Query: 1018 LITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEP 1077
++ E G T S+L P G R SDFS+
Sbjct: 433 ILNEGGI-------KTASNLCPDPGEPENGK-----RIGSDFSL---------------- 464
Query: 1078 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC--LGGGRRVWSAPLPRC-V 1134
GS + F SC Y L+G I C + WS P C V
Sbjct: 465 ---------GSTVQF----------SCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSI-QVQAGKGINISARTFHLAQG-DVLKI 1192
CG++ G SPN+P Y++N +C++ I V K I I+ F L G D L I
Sbjct: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 565
Query: 1193 YDGKD--KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHC 1250
DG + +L TG+ + L + S S+Q+WL +D GF++ Y E C
Sbjct: 566 GDGGEVGDPRTVLQVLTGSFVPDL-IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
Query: 1251 EDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1310
DPG P +G + D G + + C G+ L G + C E W +P CI C
Sbjct: 625 GDPGTPLYGIREGD-GFSNRDVLRFECQFGFELIGEKSIVCQ--ENNQWSANIPICIFPC 681
Query: 1311 GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG 1370
F G +LSP YP Y NNL C+W I DPG+ + L F FD E+ D L V DG
Sbjct: 682 LSNFTA-PMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 740
Query: 1371 PPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1430
+L +G+ +P + S +I+ ++F D +S GF I +++ C DPG+P
Sbjct: 741 DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 800
Query: 1431 MNGTRNGDGREPGDTVVFQCDPGY-ELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1489
+N R GD + G ++ C+ G+ + QG E ITCI ++ + W P C APCGG+ +
Sbjct: 801 INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFS 860
Query: 1490 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1549
SG ILSP +P Y S +C+W I + I + F F E NYD L ++DGP+ SP
Sbjct: 861 APSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP 920
Query: 1550 LIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL--RESCFDPGNIMNGT 1607
L+GS+ +++P+ + SSSN ++L F +D S S GF + Y++ SC DPG ++G
Sbjct: 921 LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGR 980
Query: 1608 RLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEG 1667
R G D+ +GSTV++ CD+GY L L C + W+ LP+C A CG G G
Sbjct: 981 RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRGPSG 1036
Query: 1668 TVLSPNYPKNYSVGHNCVYSIAVPK-EFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSS 1726
T+LSP YP+ Y NC +++ V + V F F HD + + T+ S
Sbjct: 1037 TILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI----TENGSFTQP 1092
Query: 1727 LSGSHSGESLP------LSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEP 1780
L+ +G LP L + +RF S I+ +GF+ + + C P
Sbjct: 1093 LA-RLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS---EYNLEPCEDPGIP 1148
Query: 1781 RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILT 1840
++G RIG F +G ++ F C+ GY L G+ I C + W+ LP C+ CG T
Sbjct: 1149 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC--LGGGRRVWSAPLPRCVAECGASAT 1206
Query: 1841 KRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAP 1900
+G +LSP YP Y+NN C++ I V G GI + +F D L YDG D
Sbjct: 1207 NNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-DVLKIYDGKDKTTH 1265
Query: 1901 RLGSYSGTTIPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIK 1959
LG+++G ++ L L+STSN L+L F SD + GF L YT+ L C +P P G K
Sbjct: 1266 LLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYK 1325
Query: 1960 IGDR-YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM-SDFSGV 2017
I D+ + G + + C+ GY+L G S + CM G R W+YP+P C+A+CGG + SG
Sbjct: 1326 ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGR 1385
Query: 2018 ILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRL 2077
ILSPG+P Y ++L C W I + G V LQF+ F TE HD L V G E ++ +
Sbjct: 1386 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEI 1445
Query: 2078 SGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFT 2137
SG IP + ST + ++ F +D+ +K GF I + + +C DP NG G+
Sbjct: 1446 SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGRE 1505
Query: 2138 VGQTISFECFPGYTLIGNSALTCLHGVSRN-WNHPLPRCEALCGGNITAMNGTIYSPGYP 2196
G T+ F+C PGY L G +TC+ +R W P C A CGGN+T +G I SP +P
Sbjct: 1506 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1565
Query: 2197 DEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALE 2256
YP+ +DC W + V I + F EP YDF+ ++DGPD NSP IG F + E
Sbjct: 1566 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1625
Query: 2257 SVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDII 2315
+ S+SN + + F SD + S F L Y A C P + N L D +++G +
Sbjct: 1626 RIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD--YKLGSTV 1683
Query: 2316 RYQCLPGFTLVGNAILTCRLGE--RLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2373
Y C G+ L G + LTC +G+ R + A P C C + S G +LSP YP +
Sbjct: 1684 TYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRS--TGSEGTVLSPNYPKN 1741
Query: 2374 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Y C +SI+V K + + FFQT DV++VYDGP QS +L SLSG +S
Sbjct: 1742 YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLH-DVVEVYDGPTQQSSLLSSLSGSHSGESL 1800
Query: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAF------YCSTPESPPHGYIISQTGGQLNSV 2487
S+G+++ +++++ KGF Y A CS+ P G I + S
Sbjct: 1801 PLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFA-VGSS 1859
Query: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYL-- 2545
V + C+ G+ L G + C W+ +P C + CG G IL+ Y
Sbjct: 1860 VLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEP 1918
Query: 2546 ------------------VGTRVTYFC---------------NDGYRLSSKELTTAVCQS 2572
+ +V F N+ RL S TT
Sbjct: 1919 YDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLL 1978
Query: 2573 DGTWSN----------------HNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTC 2616
+ T +N H + + SC E TP +G KIG + G F C
Sbjct: 1979 NSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQC 2038
Query: 2617 DLGFMLVGSAVRECLSSGL--WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQC 2674
D G+ L G + C+ + W+ CLA CG +G ++ + C
Sbjct: 2039 DQGYSLQGHSHITCMPGPVRRWNYPIPICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDC 2097
Query: 2675 NPGFRL-IGSSVRICQQDHNWSGQ-LPSCVPVSCG-HPGSPIYGRTSGNGFNFNDVVTFS 2731
L IG V + Q N+S + + + V G S + GR SG + T
Sbjct: 2098 TWTINLPIGFGVHL--QFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTH 2155
Query: 2732 CNIGYLMQGPTKAQCQANRQWSHPPPMC-KVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2790
Y + N+Q H ++ +C DP R + +FT G +
Sbjct: 2156 ETSLYF-----HSDYSQNKQGFHIVYQAYQLQSCPDP----RPFRNGFVIGNDFTVGQTI 2206
Query: 2791 FYDCNPGYFLFGSSVLIC--QPNGQWDKPLPECIMIDCG-----------HPGVP---PN 2834
++C PGY L G+S L C + W+ PLP C + CG PG P PN
Sbjct: 2207 SFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPN 2265
Query: 2835 --------------------AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 2874
VL E TV +GQ S L +S
Sbjct: 2266 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2325
Query: 2875 SQP-----HCSGDATG------------TCGDPGTPGHGS--RQESNFRTKSTVRYACDT 2915
S H +G C P + ++ F +RY C
Sbjct: 2326 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2385
Query: 2916 GYILHGSEERTCLANG--SWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCM 2973
G+ L G+ TC G P C+ + N R+D S+ VI S
Sbjct: 2386 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE--------LRLD----STGVILS-- 2431
Query: 2974 EGYILSGPSVRQCTANGTWSGTLP---NCTI-ISCGDPGIPANGLRYGDDYVVGQNVSYM 3029
GY S P+++ C WS ++ N T+ + + L+ D + V
Sbjct: 2432 PGYPDSYPNLQMC----AWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLIS 2487
Query: 3030 CQPGYTMELNGSRIRTCTING-----TWS--------GVMPTCRAVTCPTPPQISNGR-L 3075
Y+ N T NG WS G A C TP +G +
Sbjct: 2488 LSGDYSSAFN------ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYII 2541
Query: 3076 EGTNFDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKFCGDPGIPAQG 3131
T + + C G+ L + C G W VP C CG P P G
Sbjct: 2542 SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG 2601
Query: 3132 KREGKSFIYQSEVSFSCNFPFILVGS--STRICQADGTWS--GSSPHCIEPTQTSCENPG 3187
++ + V++ CN + L +T +CQ+DGTWS +P C+ T S N
Sbjct: 2602 GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI-NSF 2660
Query: 3188 VPRHGSQN--NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS--GIQPECIPHSCK 3243
+ HG N ++ + V F C G+ G + CLP+ TWS +P C SC
Sbjct: 2661 ILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2720
Query: 3244 QPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKI 3303
+ TP + N +G S+G T I+TC GF L G R C S W+ C AG
Sbjct: 2721 ELPTPPNGNKIGTQ-TSYGSTAIFTCDLGFMLVGSAV-RECLSSGLWSESETRCLAGH-- 2776
Query: 3304 LVKDPRPALGTPSPKLSVPDDVFAQNY 3330
P+L V V +NY
Sbjct: 2777 ----------CGIPELIVNGQVIGENY 2793
Score = 608 bits (1567), Expect = e-173
Identities = 289/302 (95%), Positives = 289/302 (95%), Gaps = 1/302 (0%)
Query: 42 SGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN 101
S F W V L GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN
Sbjct: 3 SWFLCWKPV-QLDRQTASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERN 61
Query: 102 RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV 161
RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV
Sbjct: 62 RIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAV 121
Query: 162 SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 221
SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN
Sbjct: 122 SAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIAN 181
Query: 222 SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL
Sbjct: 182 SVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 241
Query: 282 IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP 341
IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP
Sbjct: 242 IFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAP 301
Query: 342 YQ 343
YQ
Sbjct: 302 YQ 303
Score = 189 bits (480), Expect = 4e-47
Identities = 105/288 (36%), Positives = 149/288 (51%), Gaps = 13/288 (4%)
Query: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
+ TCG L+G +GT SP FP+ Y + A C WVI A N+ IQI F+ F LE YD L+
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLS 80
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
+ DG P LTG +P + S S L L +D +V + GFKV Y+E++ SC
Sbjct: 81 LYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN----QWSANIPICIF- 615
G+PG P G+ G F D +R+ C G+ L G + C N+ W +PIC
Sbjct: 139 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
Query: 616 -PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
C G + SP +P Y NN +C WTI+++PG I L F DF +E ++D+L ++
Sbjct: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
Query: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 722
+ P +G +P + SN + LRL F D + RGF+ Y
Sbjct: 259 GSEPPTI----WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 174 bits (442), Expect = 1e-42
Identities = 103/318 (32%), Positives = 155/318 (48%), Gaps = 44/318 (13%)
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
CGGT++G +G I SP FP Y N A+CTW I+AE + I ++F F +EE+YDYL +
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 301 EP-PTIW---LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
P PT + L+G ++PPP+ S K+ L +D GF Y+
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE------------- 131
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
+ S+ C +PG P G G+ F +G +++SC Y+L G
Sbjct: 132 -------------------ELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDG 172
Query: 417 AKSITCQRIAEVFAAWSDHRPVCKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT 475
+TC + A+W P+C+ + CG ++G SG +SP+FP +Y +NA C W I
Sbjct: 173 HPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIV 232
Query: 476 AVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWL 535
A I + F +F +E YD L I E +P T+ L+G +P I+S + + L
Sbjct: 233 A-EPGDTISLIFTDFQMEEKYDYLEI----EGSEPPTIW--LSGMNIPPPIISNKNWLRL 285
Query: 536 HLQTDESVGSVGFKVNYK 553
H TD + GF Y+
Sbjct: 286 HFVTDSNHRYRGFSAPYQ 303
Score = 76.6 bits (187), Expect = 4e-13
Identities = 116/462 (25%), Positives = 168/462 (36%), Gaps = 123/462 (26%)
Query: 172 ELQSSSCGNPGVPPKGVLY---GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASW 228
E ++ CGNPG G ++ GT F + YSC+ GYIL G C AN +W
Sbjct: 3068 ECKAVQCGNPGTTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTAN----GTW 3121
Query: 229 DFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQM 288
+P C +CG ++G+ + ++Y + ++ + +PG T
Sbjct: 3122 SGTLPNCTI-ISCGDPGIPANGL----RYGDDYVVGQNVSY--MCQPGYT---------- 3164
Query: 289 EEKYDYLEIEGSEPPTIWLSG-----------MNIP-PPIISNKNWLRLHFVTDSNHRYR 336
+E+ GS T ++G + P PP ISN +F
Sbjct: 3165 ------MELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDW------- 3211
Query: 337 GFSAPYQVKKAIDFKSRGFKL-FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIG 395
GFS Y S G++L FP + + C DPG P GKR G
Sbjct: 3212 GFSISY-------ICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREG 3264
Query: 396 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC--KVKTCGSNLQGPSG 453
F S V FSC+ ++L G+ + RI + WS P C +T N P
Sbjct: 3265 KSFIYQSEVSFSCNFPFILVGSST----RICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3320
Query: 454 TFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTV 513
+ F FQ S V+Q + ++ L G T T
Sbjct: 3321 GSQNNTFGFQVGS---------------VVQFHCKKGHLLQGSTTRTC------------ 3353
Query: 514 LQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREG 573
+PDL W +Q E SC P TP + G
Sbjct: 3354 --------LPDL-------TWSGIQ--------------PECIPHSCKQPETPAHANVVG 3384
Query: 574 -DGFSNRDVLRFECQFGFELI-GEKSIVCQENNQWSANIPIC 613
D S+ L + CQ GF L G + VC+ +N W+ +PIC
Sbjct: 3385 MDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
Score = 56.2 bits (134), Expect = 6e-07
Identities = 56/223 (25%), Positives = 77/223 (34%), Gaps = 61/223 (27%)
Query: 74 GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD---------- 123
G I SPG+P YPN C W I E+ I + + F E+E+D L +YD
Sbjct: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLI 2486
Query: 124 ---------------GHP--------HPTN---FRTRLTGFHLPPPVT------------ 145
GH H N FR R F+ P +
Sbjct: 2487 SLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2546
Query: 146 STKSVFSLRLTSDFAV----------SAHGFKVYYEEL---QSSSCGNPGVPPKGVLYGT 192
SV F + S++G+ + + Q+ SCG P P G + T
Sbjct: 2547 QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTT 2606
Query: 193 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
+ VG ++ Y C GY L T + S T S P C
Sbjct: 2607 DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2649
Score = 32.3 bits (72), Expect = 8.5
Identities = 15/50 (30%), Positives = 24/50 (48%)
Query: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 223
Q SCG PP G GT+ G ++C G++L G C+++ +
Sbjct: 2715 QIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL 2764
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 6449 bits (16731), Expect = 0.0
Identities = 3083/3268 (94%), Positives = 3110/3268 (95%), Gaps = 77/3268 (2%)
Query: 342 YQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 401
++VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG
Sbjct: 446 HRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 505
Query: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP
Sbjct: 506 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 565
Query: 462 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 521
FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF
Sbjct: 566 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 625
Query: 522 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 581
VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV
Sbjct: 626 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 685
Query: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 641
LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL
Sbjct: 686 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 745
Query: 642 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 701
NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH
Sbjct: 746 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 805
Query: 702 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 761
ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI
Sbjct: 806 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 865
Query: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 821
KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI
Sbjct: 866 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 925
Query: 822 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 881
EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF
Sbjct: 926 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 985
Query: 882 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 941
TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE
Sbjct: 986 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 1045
Query: 942 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV
Sbjct: 1046 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1105
Query: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1061
QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI
Sbjct: 1106 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1165
Query: 1062 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1121
SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG
Sbjct: 1166 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1225
Query: 1122 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1181
GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART
Sbjct: 1226 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1285
Query: 1182 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1241
FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV
Sbjct: 1286 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1345
Query: 1242 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1301
YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY
Sbjct: 1346 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1405
Query: 1302 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1361
PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS
Sbjct: 1406 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1465
Query: 1362 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1421
HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA
Sbjct: 1466 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1525
Query: 1422 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1481
TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI
Sbjct: 1526 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1585
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY
Sbjct: 1586 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1645
Query: 1542 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1601
DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG
Sbjct: 1646 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1705
Query: 1602 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1661
NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR
Sbjct: 1706 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1765
Query: 1662 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1721
STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS
Sbjct: 1766 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1825
Query: 1722 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1781
SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR
Sbjct: 1826 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1885
Query: 1782 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1841
FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK
Sbjct: 1886 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1945
Query: 1842 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1901
RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR
Sbjct: 1946 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 2005
Query: 1902 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 1961
LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG
Sbjct: 2006 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 2065
Query: 1962 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2021
DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP
Sbjct: 2066 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2125
Query: 2022 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2081
GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ
Sbjct: 2126 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2185
Query: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT 2141
IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT
Sbjct: 2186 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQT 2245
Query: 2142 ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN 2201
ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN
Sbjct: 2246 ISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPN 2305
Query: 2202 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2261
FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST
Sbjct: 2306 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2365
Query: 2262 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2321
SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP
Sbjct: 2366 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2425
Query: 2322 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA 2381
GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA
Sbjct: 2426 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA 2485
Query: 2382 WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV 2441
WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV
Sbjct: 2486 WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV 2545
Query: 2442 FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK 2501
FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK
Sbjct: 2546 FLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGK 2605
Query: 2502 SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLS 2561
SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLS
Sbjct: 2606 SSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLS 2665
Query: 2562 SKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKI-----------GTQTSYGS 2610
SKELTTAVCQSDGTWSNHNKTPRCVV++C P+ N G+ Y +
Sbjct: 2666 SKELTTAVCQSDGTWSNHNKTPRCVVVTC------PSINSFILEHGRWRIVNGSHYEYKT 2719
Query: 2611 TAIFTCDLGFMLVGSAVRECLSSGLWSESETR--CLAGHCGIPELIVNGQVIGENYGYRD 2668
+F+CD G+ +G A ECL +G WS R C CG NG IG Y
Sbjct: 2720 KVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS 2779
Query: 2669 TVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVV 2728
T ++ C+ GF L+GS+VR C WS C+ CG P + G+ G + + D V
Sbjct: 2780 TAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTV 2839
Query: 2729 TFSCNIGYLMQGPTKAQCQANRQWS------------HP--------------------- 2755
+ CN G+ + G + CQ + WS HP
Sbjct: 2840 VYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTF 2899
Query: 2756 ------------------------PP-MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2790
PP MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV
Sbjct: 2900 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2959
Query: 2791 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY 2850
FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY
Sbjct: 2960 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY 3019
Query: 2851 SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVR 2910
SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVR
Sbjct: 3020 SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVR 3079
Query: 2911 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 2970
YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY
Sbjct: 3080 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 3139
Query: 2971 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3030
SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC
Sbjct: 3140 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3199
Query: 3031 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYIC 3090
QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYIC
Sbjct: 3200 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYIC 3259
Query: 3091 SPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNF 3150
SPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNF
Sbjct: 3260 SPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNF 3319
Query: 3151 PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC 3210
PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC
Sbjct: 3320 PFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHC 3379
Query: 3211 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ 3270
KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ
Sbjct: 3380 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ 3439
Query: 3271 PGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3330
PGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY
Sbjct: 3440 PGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3499
Query: 3331 IWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLI 3390
IWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLI
Sbjct: 3500 IWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLI 3559
Query: 3391 KVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNS 3450
KVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNS
Sbjct: 3560 KVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNS 3619
Query: 3451 SNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFEN 3510
SNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFEN
Sbjct: 3620 SNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFEN 3679
Query: 3511 PMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
PMYDTNAKSVEGKAVRFDPNLNTVCTMV
Sbjct: 3680 PMYDTNAKSVEGKAVRFDPNLNTVCTMV 3707
Score = 1778 bits (4605), Expect = 0.0
Identities = 1062/3097 (34%), Positives = 1543/3097 (49%), Gaps = 187/3097 (6%)
Query: 175 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
S+ C +PG P G G+ F +G +++SC Y+L G +TC + A+W P+
Sbjct: 483 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 542
Query: 235 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVA-EPGDTISLIFTDFQMEEKYD 293
C+ + CG ++G SG +SP+FP +Y +NA C W I A I + F +F +E YD
Sbjct: 543 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 601
Query: 294 YLEI----EGSEPPTIW--LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKA 347
L I E +P T+ L+G +P I+S + + LH TD + GF Y K
Sbjct: 602 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 658
Query: 348 IDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFS 407
I+ +S C DPG P G R G FS ++F
Sbjct: 659 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDVLRFE 689
Query: 408 CDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSN 467
C + L G KSI CQ + WS + P+C + C SN P GT SP++P Y +N
Sbjct: 690 CQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNN 744
Query: 468 AQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIV 527
C+W I + + I ++F +FDLE +D L + DG P +L TG+ VP +
Sbjct: 745 LNCIWTIIS-DPGSRIHLSFNDFDLESQFDFLAVKDGDSPESP--ILGTFTGAEVPSHLT 801
Query: 528 SMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQ 587
S S + L Q D S+ GF + Y C DPG P+ R GD F + C+
Sbjct: 802 SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICE 861
Query: 588 FGF-ELIGEKSIVC---QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
GF + G ++I C WS IP C PC +F+AP G +LSP +P Y ++LNC
Sbjct: 862 EGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNC 921
Query: 644 IWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
W I ++PG I ++F F E +D L V DG + SP+LG++ G +VP L S+S+ +
Sbjct: 922 EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI 981
Query: 704 RLEFQADHSMSGRGFNITYNTFGHN--ECPDPGIPINARRFGDNFQLGSSISVICEEGFI 761
L F D+S S GF I Y + N C DPGIP++ RR+G +F +GS++S C+ G+
Sbjct: 982 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGY- 1040
Query: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 821
+ E + C + WS +P C A CGG PSG ILSPG+P +Y +SLNC W +
Sbjct: 1041 RLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTV 1097
Query: 822 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSS--SNF-IY 878
+ G ++ F F E ++D L + + + P L G+ +P + + NF
Sbjct: 1098 DVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQ 1156
Query: 879 LLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRL 938
L F +D S S GF I + N C DPGIP +G R G +F IG T++FSC SGYRL
Sbjct: 1157 LRFISDFSISYEGFNITFSE--YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRL 1214
Query: 939 SHEEPLLC--EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVT 996
++C WS PLP C A CG G +LSP YP Y N+ C +++ V
Sbjct: 1215 EGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQ 1274
Query: 997 HGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI 1056
GKG+ + TFHL + T L TG+ + + + + L F
Sbjct: 1275 AGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSST--SNQLWLEFN 1332
Query: 1057 SDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIG-FNFGIGDTLTFSCSSGYRLEGTSE 1115
SD + EGF + ++ + L CEDPGIPQ+G +I G T+ + C+ GY L G+S
Sbjct: 1333 SDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSL 1392
Query: 1116 IICLGGGRRVWSAPLPRCVAECGAS-ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKG 1174
+ C+ G RR W PLP C+AECG + G +LSP YP Y+NN C++ I+V G
Sbjct: 1393 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1452
Query: 1175 INISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1233
+++ F A D+L+++DG + LL +G S+ + ST N + ++F++D
Sbjct: 1453 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISG-SLIPEGIHSTLNIVTIQFDTDFYI 1511
Query: 1234 TDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMT 1293
+ GF + ++S + C DPG+P G + D G G T+++ C+PGY L G + C+
Sbjct: 1512 SKSGFAIQFSSSVATACRDPGVPMNGTRNGD-GREPGDTVVFQCDPGYELQGEERITCIQ 1570
Query: 1294 GERR-AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQ 1352
E R W P CIA CGG G SSG ILSP +P PY ++ C W I V+ ++SL
Sbjct: 1571 VENRYFWQPSPPVCIAPCGGNLTG-SSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1629
Query: 1353 FLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGF 1412
F++F E ++D L ++DGP N L+ S +PE I S+ N + + F +D +S +GF
Sbjct: 1630 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1689
Query: 1413 AIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVEN-RY 1471
+++ + + +C DPG MNGTR G + G TV + CD GY LQG +TCI ++ R
Sbjct: 1690 HLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRP 1749
Query: 1472 FWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSI 1531
W + P C APCG TGS G +LSPN+P Y +C ++I V ++V+ F+ F
Sbjct: 1750 GWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT 1809
Query: 1532 EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE-SSSNTMHLAFRSDGSVSYTGFHLEYK 1590
+D + +YDGP S L+ S S E + SS N + + F S G ++ GFH Y+
Sbjct: 1810 S-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQ 1868
Query: 1591 AKLRES---CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGW 1647
A R S C G R+G ++ +GS+V + C+ GY+L G + C + W
Sbjct: 1869 AVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQW 1928
Query: 1648 NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL 1707
N +LP+C PCG T +GT+LSP YP+ Y NCV+ I VP+ + Q V F T
Sbjct: 1929 NDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEH 1988
Query: 1708 H-DVVEVYDGPTQQSSLLSSLSGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHFVY 1763
+ D ++ YDG + L GS+SG ++P S+ N + + F S ++A GFH Y
Sbjct: 1989 NWDSLDFYDGGDNNAPRL----GSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 2044
Query: 1764 QAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
A+ S C P G +IG+ + VG V F C+ GY L G I C +P + +
Sbjct: 2045 TAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC--MPGPVRR 2099
Query: 1824 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1883
WN +P C+ CGG ++ G ILSPG+P Y ++L+C W I +P G G+ +Q V+F+TE
Sbjct: 2100 WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE 2159
Query: 1884 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
D L+ G + +G SG IP L ST++ L F SD S + GFH+ Y A
Sbjct: 2160 TIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAY 2219
Query: 1944 GLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
L SCP+P+ +G IG+ + VG +SF+C GY+L G+S +TC+ G R WN+P+P C
Sbjct: 2220 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2279
Query: 2004 LAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
A CGG ++ +G I SPG+P YP+ DC W + +P G G+++ F TE I+D++ V
Sbjct: 2280 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITV 2339
Query: 2064 RSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIV-YQAYQLQSCPD 2122
G + S IG+ SG S++ST+++ + FHSD++ + GF ++ Y AYQL+ C
Sbjct: 2340 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2397
Query: 2123 PRPFRNGFVIGND--FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
P P N ++ D F +G I ++C PG+TL+GN+ LTC G + P C+ LC
Sbjct: 2398 PPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCP 2457
Query: 2181 GNITAMN--GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238
N ++ G I SPGYPD YPN Q C W + V G I + QTE +D + V+DG
Sbjct: 2458 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2517
Query: 2239 PDQNSPQIGQFSGN-TALESVYSTSNQILIKFHSDF-TTSGFFVLSYHAYQLRVCQPPPP 2296
P+ SP + SG+ ++ ++ S +++ +++ +D F + Y A+ C P
Sbjct: 2518 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPES 2574
Query: 2297 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE--RLQMDGAPPVCQVLCPA 2354
P+ I+++ ++ ++R+ C GF LVG + CR D P CQ +
Sbjct: 2575 PPHGYIISQTGG-QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SC 2632
Query: 2355 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVE---FFQTEKEFDVLQVY 2411
+ + G IL+ Y C + T + + + V
Sbjct: 2633 GIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVV 2692
Query: 2412 DGPNIQSPVLISLSGDYSSAFNITSNGHEVF---LQWSADHGNNKKG-----------FR 2457
P+I S +L + I + H + + +S D G + G +
Sbjct: 2693 TCPSINSFIL------EHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2746
Query: 2458 IRYIAFYCSTPE-----SPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2512
R YC +PP+G I T S + CD GF LVG + C S
Sbjct: 2747 WRNERPYCQIISCGELPTPPNGNKIG-TQTSYGSTAIFTCDLGFMLVGSAVRECLSSG-- 2803
Query: 2513 YHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQS 2572
W C A CGIP+ NG ++ +Y V Y CN G+RL + +CQ
Sbjct: 2804 --LWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS--SVRICQQ 2859
Query: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLS 2632
D WS + P CV +SCG +P G G ++ F+C++G+++ G +C +
Sbjct: 2860 DHNWS--GQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2917
Query: 2633 SGLWSESETRCLAGHCGIPELIVN----GQVIGENYGYRDTVVYQCNPGFRLIGSSVRIC 2688
+ WS C +C P + N ++ N+ Y V Y CNPG+ L GSSV IC
Sbjct: 2918 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2977
Query: 2689 QQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2748
Q + W LP C+ + CGHPG P SG + F V +SC + G + CQ
Sbjct: 2978 QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQL 3037
Query: 2749 NRQWSHPPPMCK---VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSV 2805
N WS P C C DPG P + R + NF + V Y C+ GY L GS
Sbjct: 3038 NGHWSGSQPHCSGDATGTCGDPGTPGHGSR----QESNFRTKSTVRYACDTGYILHGSEE 3093
Query: 2806 LICQPNGQWDKPLPECIMIDCGHPGVPPNA-VLSGEKYTFGSTVHYSCTGKRSLLGQSSR 2864
C NG W PEC + CG+PG N V + TF S+V YSC L G S R
Sbjct: 3094 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVR 3153
Query: 2865 TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYI--LHGS 2922
C NG WSG+ P+C+ +CGDPG P +G R ++ V Y C GY L+GS
Sbjct: 3154 QCTANGTWSGTLPNCT---IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3210
Query: 2923 EERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF--SSSVIYSCMEGYILSG 2980
RTC NG+W+G P C+AV C P +NG R++GT F S+ Y C GY LS
Sbjct: 3211 RIRTCTINGTWSGVMPTCRAVTCPTPPQISNG---RLEGTNFDWGFSISYICSPGYELSF 3267
Query: 2981 PSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNG 3040
P+V C NGTWSG +P C CGDPGIPA G R G ++ VS+ C + L G
Sbjct: 3268 PAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSC--NFPFILVG 3325
Query: 3041 SRIRTCTINGTWSGVMPTC---RAVTCPTPPQISNGRLEGT-NFDWGFSISYICSPGYEL 3096
S R C +GTWSG P C +C P +G T F G + + C G+ L
Sbjct: 3326 SSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL 3385
Query: 3097 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK-------REGKSFIYQSEVSFSCN 3149
TC+ + TWSG P+C+P C P PA G + IY + F
Sbjct: 3386 QGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGF--- 3442
Query: 3150 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENP 3186
F+ G+ R+C++D TW+G P C ++ ++P
Sbjct: 3443 --FLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3477
Score = 1280 bits (3312), Expect = 0.0
Identities = 783/2181 (35%), Positives = 1137/2181 (52%), Gaps = 124/2181 (5%)
Query: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLS 120
+ TCG L+G +GT SP FP+ Y + A C WVI A N+ IQI F+ F LE YD L+
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 604
Query: 121 LYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
+ DG P LTG +P + S S L L +D +V + GFKV Y+E++ SC
Sbjct: 605 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 664
Query: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
G+PG P G+ G F D +R+ C G+ L G + C N+ W +PIC
Sbjct: 665 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN----QWSANIPICIF- 719
Query: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
C G + SP +P Y NN +C WTI+++PG I L F DF +E ++D+L ++
Sbjct: 720 -PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 778
Query: 299 GSEPPTI----WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRG 354
+ P +G +P + SN + LRL F D + RGF+ Y
Sbjct: 779 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY------------ 826
Query: 355 FKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV- 413
N F N CPDPG P N +R G +F LGS++ C+E ++
Sbjct: 827 ----------NTF----------GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIK 866
Query: 414 LQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWV 473
QG ++ITC + + WS P C CG + PSG SP +P Y + C WV
Sbjct: 867 TQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCEWV 924
Query: 474 ITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQM 533
I A I+I FE F E+ YD L + DG + P +L G+ VP + S S+ +
Sbjct: 925 IEA-EPGHSIKITFERFQTELNYDVLEVHDGPNLLSP--LLGSYNGTQVPQFLFSSSNFI 981
Query: 534 WLHLQTDESVGSVGFKVNYKE--IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 591
+L TD S + GFK++Y+ + SC DPG P++G R G FS + F C G+
Sbjct: 982 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYR 1041
Query: 592 LIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDP 651
L E+ ++C++N+ WS +P C C + P GT+LSP YPE Y N+LNC WT+
Sbjct: 1042 LSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH 1101
Query: 652 GSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTS---NSHILRLEFQ 708
G + +F+ F LE D+L + + S P L TG+++P + + + +L F
Sbjct: 1102 GKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFI 1160
Query: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTET 768
+D S+S GFNIT++ + C DPGIP R G NF +G +++ C G+ + +GT
Sbjct: 1161 SDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGTSE 1219
Query: 769 ITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
I C L G+ +WS +P+C A CG + G++LSP +P Y+++ C + I+ + G
Sbjct: 1220 IIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKG 1278
Query: 829 IKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQF-LFSSSNFIYLLFTTDNSR 887
I I+ F DVL+++DG + + LLG++ G + L S+SN ++L F +D
Sbjct: 1279 INISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1337
Query: 888 SNNGFKIHYESVTVNTYSCLDPGIPVHGRR---YGHDFSIGSTVSFSCDSGYRLSHEEPL 944
++ GF++ Y S ++ C DPGIP G + GH GST+ + C+ GY L L
Sbjct: 1338 TDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGH--FAGSTIIYGCNPGYTLHGSSLL 1393
Query: 945 LC--EKNHWWSHPLPTCDALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
C + W +PLP+C A CGG +G SG ILSPGYP Y N+L C W ++V G V
Sbjct: 1394 KCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIV 1453
Query: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPLAR-LTGSDLPPTINAGLYGNFRAQLRFISDFS 1060
F F E HD L + + L + ++GS +P I++ L ++F +DF
Sbjct: 1454 SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFDTDFY 1510
Query: 1061 ISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1120
IS GF I FS C DPG+P G+R G GDT+ F C GY L+G I C+
Sbjct: 1511 ISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQ 1570
Query: 1121 -GGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISA 1179
R W P C+A CG + T + G +LSPN+P Y ++ +C ++I V A I+++
Sbjct: 1571 VENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAF 1630
Query: 1180 RTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGF 1238
+F + D L IYDG D + L+G+F + + + S+SN + L F SD + GF
Sbjct: 1631 ISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVSYTGF 1689
Query: 1239 QLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGE--R 1296
L Y + C DPG G ++ + GST+ Y C+ GY L G S L C+ G+ R
Sbjct: 1690 HLEYKAKLRESCFDPGNIMNGTRLG-MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGR 1748
Query: 1297 RAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAF 1356
W+ LPSC A CG R G S G +LSP YP Y C++ I V +V QF+ F
Sbjct: 1749 PGWNRALPSCHAPCGSRSTG-SEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFF 1807
Query: 1357 DTEASHDILRVWDGPPENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQ 1415
T + HD++ V+DGP + LL +SGS E + S+ N +TI+F + I+ GF
Sbjct: 1808 QT-SLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFV 1866
Query: 1416 FSS---SVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF 1472
+ + + +T C P G R G+ G +V+F C+PGY L G I C V N
Sbjct: 1867 YQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLA 1926
Query: 1473 -WQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSI 1531
W S P CI PCGG LT G ILSP +P PY ++ +C W ITV I + +SF+
Sbjct: 1927 QWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFAT 1986
Query: 1532 EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
E N+D L YDG D+N+P +GS+ + +P + S+SN ++L F+SD SVS GFHLEY A
Sbjct: 1987 EHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2046
Query: 1592 KLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1651
+SC +P +G ++G Y +G V++ CD GY LQG+S +TC+ G R WN +
Sbjct: 2047 IGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYPI 2104
Query: 1652 PSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT-SLHDV 1710
P C A CG + G +LSP +P NY +C ++I +P F V QFV F T ++HD
Sbjct: 2105 PICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDY 2164
Query: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
+EV G ++ S+++ LSG SL S+ ++ ++ F S +GFH VYQA
Sbjct: 2165 LEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY---- 2219
Query: 1771 STQCSSVPEPRFGRR---IGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1827
Q S P+PR R IGN+F VG ++ F+C PGY L G+ A+ C + WN
Sbjct: 2220 --QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNHP 2275
Query: 1828 LPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWD 1887
LP C CGG +T GTI SPGYP+ Y N +C W + VP G GI + TE +D
Sbjct: 2276 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD 2335
Query: 1888 SLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDS 1947
+ +DG D N+P++G +SG T + STSN + + F SD + S F L Y A L
Sbjct: 2336 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLRV 2394
Query: 1948 C-PEPQTPSSGIKI-GDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
C P P P++ I D + +GD++ +QC G++L G++ +TC G + + P+C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Query: 2006 QC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
C D +GVILSPG+P +YP+ C W+I++ G+ + + F TE D L+V
Sbjct: 2455 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2514
Query: 2064 RSGSSETSTVIGRLSGPQIPSSLFSTT---HETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
G + S V+ LSG SS F+ T HE L + +D+ NK+GF I Y A+ C
Sbjct: 2515 YDGPNIQSPVLISLSGDY--SSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---C 2569
Query: 2121 PDPRPFRNGFVIGNDFTVGQ---TISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRC 2175
P +G++I T GQ + + C G+ L+G S+ C W+ P+P C
Sbjct: 2570 STPESPPHGYIISQ--TGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2627
Query: 2176 EAL-CGGNITAMNGTIYSPGY 2195
+A+ CG NG I + Y
Sbjct: 2628 QAISCGIPKAPTNGGILTTDY 2648
Score = 1077 bits (2786), Expect = 0.0
Identities = 859/2907 (29%), Positives = 1253/2907 (43%), Gaps = 325/2907 (11%)
Query: 614 IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 673
I+ C GT+ SP +P GY N NC W II++ +RI + F F LE ++D+L++
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
Query: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 733
DG + TG +P +TS + L +D ++S GF + Y + C +P
Sbjct: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMD-GKVMWSGLIPKCGA--P 790
G+P +G F +G I C G+I G +TCI W +P C A
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 791 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 850
CGG SG+I SP +P Y ++ +C W I AEPG +I + F FQ E YD LE+
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
Query: 851 PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 910
P +G +P + S+ N++ L F TD++ GF Y+ + T++
Sbjct: 301 ----EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 356
Query: 911 IPVHGRRYGHDFSIGST------VSFSCDSGYRLSHEEPL-LCEKNHWWSHPLPTCDALC 963
+ H R ++ ST S + + +RLS E+ + + + P + D L
Sbjct: 357 LEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLS 416
Query: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH--GKGVQFNFHTFHL----EDHHDYL 1017
P+ T + P VTH K + F F L ++ + +
Sbjct: 417 ----PHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFS 472
Query: 1018 LITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEP 1077
++ E G T S+L P G R SDFS+
Sbjct: 473 ILNEGGI-------KTASNLCPDPGEPENGK-----RIGSDFSL---------------- 504
Query: 1078 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC--LGGGRRVWSAPLPRC-V 1134
GS + F SC Y L+G I C + WS P C V
Sbjct: 505 ---------GSTVQF----------SCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSI-QVQAGKGINISARTFHLAQG-DVLKI 1192
CG++ G SPN+P Y++N +C++ I V K I I+ F L G D L I
Sbjct: 546 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 605
Query: 1193 YDGKD--KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHC 1250
DG + +L TG+ + L + S S+Q+WL +D GF++ Y E C
Sbjct: 606 GDGGEVGDPRTVLQVLTGSFVPDL-IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 664
Query: 1251 EDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1310
DPG P +G + D G + + C G+ L G + C E W +P CI C
Sbjct: 665 GDPGTPLYGIREGD-GFSNRDVLRFECQFGFELIGEKSIVCQ--ENNQWSANIPICIFPC 721
Query: 1311 GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG 1370
F G +LSP YP Y NNL C+W I DPG+ + L F FD E+ D L V DG
Sbjct: 722 LSNFTA-PMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 780
Query: 1371 PPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1430
+L +G+ +P + S +I+ ++F D +S GF I +++ C DPG+P
Sbjct: 781 DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 840
Query: 1431 MNGTRNGDGREPGDTVVFQCDPGY-ELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1489
+N R GD + G ++ C+ G+ + QG E ITCI ++ + W P C APCGG+ +
Sbjct: 841 INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFS 900
Query: 1490 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1549
SG ILSP +P Y S +C+W I + I + F F E NYD L ++DGP+ SP
Sbjct: 901 APSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP 960
Query: 1550 LIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL--RESCFDPGNIMNGT 1607
L+GS+ +++P+ + SSSN ++L F +D S S GF + Y++ SC DPG ++G
Sbjct: 961 LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGR 1020
Query: 1608 RLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEG 1667
R G D+ +GSTV++ CD+GY L L C + W+ LP+C A CG G G
Sbjct: 1021 RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRGPSG 1076
Query: 1668 TVLSPNYPKNYSVGHNCVYSIAVPK-EFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSS 1726
T+LSP YP+ Y NC +++ V + V F F HD + + T+ S
Sbjct: 1077 TILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI----TENGSFTQP 1132
Query: 1727 LSGSHSGESLP------LSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEP 1780
L+ +G LP L + +RF S I+ +GF+ + + C P
Sbjct: 1133 LA-RLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS---EYNLEPCEDPGIP 1188
Query: 1781 RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILT 1840
++G RIG F +G ++ F C+ GY L G+ I C + W+ LP C+ CG T
Sbjct: 1189 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC--LGGGRRVWSAPLPRCVAECGASAT 1246
Query: 1841 KRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAP 1900
+G +LSP YP Y+NN C++ I V G GI + +F D L YDG D
Sbjct: 1247 NNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-DVLKIYDGKDKTTH 1305
Query: 1901 RLGSYSGTTIPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIK 1959
LG+++G ++ L L+STSN L+L F SD + GF L YT+ L C +P P G K
Sbjct: 1306 LLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYK 1365
Query: 1960 IGDR-YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM-SDFSGV 2017
I D+ + G + + C+ GY+L G S + CM G R W+YP+P C+A+CGG + SG
Sbjct: 1366 ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGR 1425
Query: 2018 ILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRL 2077
ILSPG+P Y ++L C W I + G V LQF+ F TE HD L V G E ++ +
Sbjct: 1426 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEI 1485
Query: 2078 SGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFT 2137
SG IP + ST + ++ F +D+ +K GF I + + +C DP NG G+
Sbjct: 1486 SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGRE 1545
Query: 2138 VGQTISFECFPGYTLIGNSALTCLHGVSRN-WNHPLPRCEALCGGNITAMNGTIYSPGYP 2196
G T+ F+C PGY L G +TC+ +R W P C A CGGN+T +G I SP +P
Sbjct: 1546 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1605
Query: 2197 DEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALE 2256
YP+ +DC W + V I + F EP YDF+ ++DGPD NSP IG F + E
Sbjct: 1606 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1665
Query: 2257 SVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDII 2315
+ S+SN + + F SD + S F L Y A C P + N L D +++G +
Sbjct: 1666 RIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD--YKLGSTV 1723
Query: 2316 RYQCLPGFTLVGNAILTCRLGE--RLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2373
Y C G+ L G + LTC +G+ R + A P C C + S G +LSP YP +
Sbjct: 1724 TYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRS--TGSEGTVLSPNYPKN 1781
Query: 2374 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Y C +SI+V K + + FFQT DV++VYDGP QS +L SLSG +S
Sbjct: 1782 YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLH-DVVEVYDGPTQQSSLLSSLSGSHSGESL 1840
Query: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAF------YCSTPESPPHGYIISQTGGQLNSV 2487
S+G+++ +++++ KGF Y A CS+ P G I + S
Sbjct: 1841 PLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFA-VGSS 1899
Query: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYL-- 2545
V + C+ G+ L G + C W+ +P C + CG G IL+ Y
Sbjct: 1900 VLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEP 1958
Query: 2546 ------------------VGTRVTYFC---------------NDGYRLSSKELTTAVCQS 2572
+ +V F N+ RL S TT
Sbjct: 1959 YDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLL 2018
Query: 2573 DGTWSN----------------HNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTC 2616
+ T +N H + + SC E TP +G KIG + G F C
Sbjct: 2019 NSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQC 2078
Query: 2617 DLGFMLVGSAVRECLSSGL--WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQC 2674
D G+ L G + C+ + W+ CLA CG +G ++ + C
Sbjct: 2079 DQGYSLQGHSHITCMPGPVRRWNYPIPICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDC 2137
Query: 2675 NPGFRL-IGSSVRICQQDHNWSGQ-LPSCVPVSCG-HPGSPIYGRTSGNGFNFNDVVTFS 2731
L IG V + Q N+S + + + V G S + GR SG + T
Sbjct: 2138 TWTINLPIGFGVHL--QFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTH 2195
Query: 2732 CNIGYLMQGPTKAQCQANRQWSHPPPMC-KVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2790
Y + N+Q H ++ +C DP R + +FT G +
Sbjct: 2196 ETSLYF-----HSDYSQNKQGFHIVYQAYQLQSCPDP----RPFRNGFVIGNDFTVGQTI 2246
Query: 2791 FYDCNPGYFLFGSSVLIC--QPNGQWDKPLPECIMIDCG-----------HPGVP---PN 2834
++C PGY L G+S L C + W+ PLP C + CG PG P PN
Sbjct: 2247 SFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPN 2305
Query: 2835 --------------------AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 2874
VL E TV +GQ S L +S
Sbjct: 2306 FQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYST 2365
Query: 2875 SQP-----HCSGDATG------------TCGDPGTPGHGS--RQESNFRTKSTVRYACDT 2915
S H +G C P + ++ F +RY C
Sbjct: 2366 SNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLP 2425
Query: 2916 GYILHGSEERTCLANG--SWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCM 2973
G+ L G+ TC G P C+ + N R+D S+ VI S
Sbjct: 2426 GFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE--------LRLD----STGVILS-- 2471
Query: 2974 EGYILSGPSVRQCTANGTWSGTLP---NCTI-ISCGDPGIPANGLRYGDDYVVGQNVSYM 3029
GY S P+++ C WS ++ N T+ + + L+ D + V
Sbjct: 2472 PGYPDSYPNLQMC----AWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLIS 2527
Query: 3030 CQPGYTMELNGSRIRTCTING-----TWS--------GVMPTCRAVTCPTPPQISNGR-L 3075
Y+ N T NG WS G A C TP +G +
Sbjct: 2528 LSGDYSSAFN------ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYII 2581
Query: 3076 EGTNFDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKFCGDPGIPAQG 3131
T + + C G+ L + C G W VP C CG P P G
Sbjct: 2582 SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG 2641
Query: 3132 KREGKSFIYQSEVSFSCNFPFILVGS--STRICQADGTWS--GSSPHCIEPTQTSCENPG 3187
++ + V++ CN + L +T +CQ+DGTWS +P C+ T S N
Sbjct: 2642 GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI-NSF 2700
Query: 3188 VPRHGSQN--NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS--GIQPECIPHSCK 3243
+ HG N ++ + V F C G+ G + CLP+ TWS +P C SC
Sbjct: 2701 ILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG 2760
Query: 3244 QPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKI 3303
+ TP + N +G S+G T I+TC GF L G R C S W+ C AG
Sbjct: 2761 ELPTPPNGNKIGTQ-TSYGSTAIFTCDLGFMLVGSAV-RECLSSGLWSESETRCLAGH-- 2816
Query: 3304 LVKDPRPALGTPSPKLSVPDDVFAQNY 3330
P+L V V +NY
Sbjct: 2817 ----------CGIPELIVNGQVIGENY 2833
Score = 729 bits (1883), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG 60
MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG
Sbjct: 1 MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG 60
Query: 61 FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS
Sbjct: 61 FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA
Sbjct: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
Query: 301 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ
Sbjct: 301 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 189 bits (480), Expect = 4e-47
Identities = 105/288 (36%), Positives = 149/288 (51%), Gaps = 13/288 (4%)
Query: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
+ TCG L+G +GT SP FP+ Y + A C WVI A N+ IQI F+ F LE YD L+
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLS 120
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
+ DG P LTG +P + S S L L +D +V + GFKV Y+E++ SC
Sbjct: 121 LYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN----QWSANIPICIF- 615
G+PG P G+ G F D +R+ C G+ L G + C N+ W +PIC
Sbjct: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 616 -PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
C G + SP +P Y NN +C WTI+++PG I L F DF +E ++D+L ++
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
Query: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 722
+ P +G +P + SN + LRL F D + RGF+ Y
Sbjct: 299 GSEPPTI----WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 174 bits (442), Expect = 1e-42
Identities = 103/318 (32%), Positives = 155/318 (48%), Gaps = 44/318 (13%)
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS 300
CGGT++G +G I SP FP Y N A+CTW I+AE + I ++F F +EE+YDYL +
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 301 EP-PTIW---LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
P PT + L+G ++PPP+ S K+ L +D GF Y+
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE------------- 171
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
+ S+ C +PG P G G+ F +G +++SC Y+L G
Sbjct: 172 -------------------ELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDG 212
Query: 417 AKSITCQRIAEVFAAWSDHRPVCKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT 475
+TC + A+W P+C+ + CG ++G SG +SP+FP +Y +NA C W I
Sbjct: 213 HPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIV 272
Query: 476 AVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWL 535
A I + F +F +E YD L I E +P T+ L+G +P I+S + + L
Sbjct: 273 A-EPGDTISLIFTDFQMEEKYDYLEI----EGSEPPTIW--LSGMNIPPPIISNKNWLRL 325
Query: 536 HLQTDESVGSVGFKVNYK 553
H TD + GF Y+
Sbjct: 326 HFVTDSNHRYRGFSAPYQ 343
Score = 76.6 bits (187), Expect = 4e-13
Identities = 116/462 (25%), Positives = 168/462 (36%), Gaps = 123/462 (26%)
Query: 172 ELQSSSCGNPGVPPKGVLY---GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASW 228
E ++ CGNPG G ++ GT F + YSC+ GYIL G C AN +W
Sbjct: 3108 ECKAVQCGNPGTTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTAN----GTW 3161
Query: 229 DFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQM 288
+P C +CG ++G+ + ++Y + ++ + +PG T
Sbjct: 3162 SGTLPNCTI-ISCGDPGIPANGL----RYGDDYVVGQNVSY--MCQPGYT---------- 3204
Query: 289 EEKYDYLEIEGSEPPTIWLSG-----------MNIP-PPIISNKNWLRLHFVTDSNHRYR 336
+E+ GS T ++G + P PP ISN +F
Sbjct: 3205 ------MELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDW------- 3251
Query: 337 GFSAPYQVKKAIDFKSRGFKL-FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIG 395
GFS Y S G++L FP + + C DPG P GKR G
Sbjct: 3252 GFSISY-------ICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREG 3304
Query: 396 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC--KVKTCGSNLQGPSG 453
F S V FSC+ ++L G+ + RI + WS P C +T N P
Sbjct: 3305 KSFIYQSEVSFSCNFPFILVGSST----RICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3360
Query: 454 TFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTV 513
+ F FQ S V+Q + ++ L G T T
Sbjct: 3361 GSQNNTFGFQVGS---------------VVQFHCKKGHLLQGSTTRTC------------ 3393
Query: 514 LQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREG 573
+PDL W +Q E SC P TP + G
Sbjct: 3394 --------LPDL-------TWSGIQ--------------PECIPHSCKQPETPAHANVVG 3424
Query: 574 -DGFSNRDVLRFECQFGFELI-GEKSIVCQENNQWSANIPIC 613
D S+ L + CQ GF L G + VC+ +N W+ +PIC
Sbjct: 3425 MDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3466
Score = 56.2 bits (134), Expect = 6e-07
Identities = 56/223 (25%), Positives = 77/223 (34%), Gaps = 61/223 (27%)
Query: 74 GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD---------- 123
G I SPG+P YPN C W I E+ I + + F E+E+D L +YD
Sbjct: 2467 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLI 2526
Query: 124 ---------------GHP--------HPTN---FRTRLTGFHLPPPVT------------ 145
GH H N FR R F+ P +
Sbjct: 2527 SLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2586
Query: 146 STKSVFSLRLTSDFAV----------SAHGFKVYYEEL---QSSSCGNPGVPPKGVLYGT 192
SV F + S++G+ + + Q+ SCG P P G + T
Sbjct: 2587 QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTT 2646
Query: 193 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
+ VG ++ Y C GY L T + S T S P C
Sbjct: 2647 DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2689
Score = 32.3 bits (72), Expect = 8.5
Identities = 15/50 (30%), Positives = 24/50 (48%)
Query: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 223
Q SCG PP G GT+ G ++C G++L G C+++ +
Sbjct: 2755 QIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL 2804
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 4835 bits (12540), Expect = 0.0
Identities = 2191/3542 (61%), Positives = 2740/3542 (77%), Gaps = 76/3542 (2%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
CGG ++G NGTIESPGFP+GYPN ANCTW+II ERNRIQ+ F +FALEE++D LS+YDG
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
Query: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 184
P N + RL+GF LP + ST S+ +L T+DFAVSA GFK YE L S +CGNPG
Sbjct: 92 QPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEI 151
Query: 185 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 244
KGVL+GTRF++GDKIRYSC+ GYIL+GH LTCI + N ASWDFP P CRAE ACGGT
Sbjct: 152 LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGT 211
Query: 245 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 304
+RG+S ISSP FP+EY NNADCTWTI+AEPGDTI+L+FTDFQ+EE YD+LEI G+E P+
Sbjct: 212 LRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPS 271
Query: 305 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNS 364
IWL+GMN+P P+IS+KNWLRLHF +DSNHR +GF+A +QVKKAI+ KSRG K+ P KD S
Sbjct: 272 IWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGS 331
Query: 365 NKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFS-LGSTVQFSCDEDYVLQGAKSITCQ 423
+K S+L++GG+ S++CPDPG PENG+R GSDFS +G+ VQFSC+++YVLQG+KSITCQ
Sbjct: 332 HKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQ 391
Query: 424 RIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVI 483
R+ E AAWSDHRP+C+ +TCGSNL+GPSG TSPN+P QY+ NA CVWVIT + +KVI
Sbjct: 392 RVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVI 451
Query: 484 QINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESV 543
++ FEEF+LE GYDTLT+GD G+VGD R+VL VLTGS VPDLIVSMS+QMWLHLQ+D+S+
Sbjct: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSI 511
Query: 544 GSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQEN 603
GS GFK Y+EIEK CGDPG P YG R G F + D L FEC FEL+GE+ I CQ+N
Sbjct: 512 GSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQN 571
Query: 604 NQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFD 663
NQWS N P C+F C NFTA G +LSP+YPE YGNN+NC+W IIS+PGSRIHL FNDFD
Sbjct: 572 NQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFD 631
Query: 664 LESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN 723
+E QFDFLAVKD + +LGTF+G EVPS L S+ HI+RLEFQ+DHS +GRGFNITY
Sbjct: 632 VEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYT 691
Query: 724 TFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 783
TFG NEC DPGIPIN RRFGD F LGSS+S C++GF+KTQG+E+ITCIL DG V+WS
Sbjct: 692 TFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSST 751
Query: 784 IPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYD 843
+P+C APCGGH +A SGVIL PGWPGYYKDSL+CEW+IEA+PGHSIKITF+RFQTE+NYD
Sbjct: 752 VPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYD 811
Query: 844 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 903
LEV DGP SPL+G Y+GTQ PQFL S+ NF+YLLFTTDNSRS+ GF IHYESVT+ +
Sbjct: 812 TLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLES 871
Query: 904 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 963
SCLDPGIPV+G R+G DF I STV+FSCD GY LS +EPL+CE+NH W+H LP+CDALC
Sbjct: 872 DSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALC 931
Query: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1023
GG ++G SGT+LSPG+P+FYPNSLNCTWT++V+HGKGVQ FHTFHLE HDYLLITE+G
Sbjct: 932 GGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDG 991
Query: 1024 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1083
SF++P+ARLTGS LP TI AGL+GNF AQLRFISDFSISYEGFNITFSEY+LEPC+DPG+
Sbjct: 992 SFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGV 1051
Query: 1084 PQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATN 1143
P + RIGF+FG+GD+LTFSC GYRLEG +++ CLGGGRRVWSAPLPRCVAECGAS
Sbjct: 1052 PAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG 1111
Query: 1144 NEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLL 1203
NEG LLSPN+P NY+NNHECIY I+ +AGKGI++ R+F L +GD LK+YDGKD ++ L
Sbjct: 1112 NEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPL 1171
Query: 1204 GAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKIS 1263
G FT + GL L+STSN LWLEFN++ TD+GFQL YTSF+L CEDPGIP +GY+I
Sbjct: 1172 GTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIR 1231
Query: 1264 DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRIL 1323
D+GHF + ++Y CNPGY +HGS+ L C++G+RR WD PLPSCIAECGG+ +SGRIL
Sbjct: 1232 DEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRIL 1291
Query: 1324 SPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISG 1383
SPGYP PYDNNL C W+IE DPG +SL F+ FDTE +HDIL+VWDGP ++D+LLKE SG
Sbjct: 1292 SPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSG 1351
Query: 1384 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPG 1443
S +PE IHST N +T+QFD+DF+ISKSGF+IQFS+S+A C DPG+P NGTR GD RE G
Sbjct: 1352 SALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAG 1411
Query: 1444 DTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHP 1503
DTV FQCDPGY+LQG+ +ITC+Q+ NR+FWQP PP CIA CGGNLTG +G ILSPN+P P
Sbjct: 1412 DTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQP 1471
Query: 1504 YPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI 1563
YP ++CDW + VN D+VI+L F SF++EP+YDFL+IY+G DSNSPLIGS+Q S+ PERI
Sbjct: 1472 YPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERI 1531
Query: 1564 ESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYC 1623
ESS N++ LAFRSD SV +GF +E+K K RE+CFDPGNIMNGTR+G D+KLGST+TY C
Sbjct: 1532 ESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQC 1591
Query: 1624 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHN 1683
D+GY + S++TC++G DG+P W++ LPSC+APCG + TGSEG VLSPNYP NY+ G
Sbjct: 1592 DSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQI 1651
Query: 1684 CVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQ 1743
C+YSI VPKEFVVFGQF +FQT+L+D+ E++DG Q+ LLSSLSGSHSGE+LPL++ NQ
Sbjct: 1652 CLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQ 1711
Query: 1744 ITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPG 1803
I +RF++ +A+GFHFVYQAVPRTS TQCSSVPEPR+GRRIG+EF+ GS V F+CNPG
Sbjct: 1712 ILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPG 1771
Query: 1804 YILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVW 1863
Y+L GS A+ C++VPN+LAQWND++P+C+VPC G T+R+GTILSPGYPEPY NNLNC+W
Sbjct: 1772 YLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIW 1831
Query: 1864 KITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYL 1923
KI V EG+GIQ+QV+SFATE NWDSL+ +DGGD APRLGS+SGTT+P LLNSTSN LYL
Sbjct: 1832 KIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYL 1891
Query: 1924 NFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGH 1983
+FQSDISV+AAGFHLEY +GL +C EP PS+ IKIGDRYMV DV+SFQC+ GY+LQG
Sbjct: 1892 HFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGR 1951
Query: 1984 SHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF 2043
SHI+CMPG VRRWNYP P+C+A CGG +S GVILSPGFPG+YP++LDCTW I+LPIG+
Sbjct: 1952 SHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 2011
Query: 2044 GVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQ 2103
G H+QF+NFSTE HD+LE+++G TS +IG+ SG +P++L STTHET ++F+SD+SQ
Sbjct: 2012 GAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQ 2071
Query: 2104 NKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHG 2163
N+QGF + YQAY+LQ+CPDP PF+NG++I +D++VGQ++SFEC+PGY LIG+ LTC HG
Sbjct: 2072 NRQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHG 2131
Query: 2164 VSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV 2223
++RNWN+P PRC+A CG N+T+ NGTIYSPG+PDEYP +DC WL+ VPPG+G+YINFT+
Sbjct: 2132 INRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTL 2191
Query: 2224 LQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSY 2283
LQTE + D+I VWDGPDQNSPQ+G FSGNTALE+ YS++NQ+L+KFHSDF+ GFFVL++
Sbjct: 2192 LQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNF 2251
Query: 2284 HAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG 2343
HA+QL+ CQPPP VP AE+LTEDD+FEIGD ++YQC PG+TLVG ILTC+L +LQ +G
Sbjct: 2252 HAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEG 2311
Query: 2344 APPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK 2403
+ P C+ CPANE+R S+GVILSPGYP +Y N Q C+WSI VE YNIT+FV+ FQ+EK
Sbjct: 2312 SLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK 2371
Query: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF 2463
+FD L+V+DG + QSP+L+ LSG+++ N TS ++++L+WS DH +KKGF+IRY A
Sbjct: 2372 QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAP 2431
Query: 2464 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2523
YCS +G I+++T G + S V + C G+R+VG S+A CR++ G + WD+ P C
Sbjct: 2432 YCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLC 2491
Query: 2524 QAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2583
QA+SCGIP++P NG ++ + ++V Y C++G++L S + TAVCQ DG WSN K P
Sbjct: 2492 QAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPP 2551
Query: 2584 RCVVISCGELPTPPNGNKI-----GTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSE 2638
C ++C + + + I G+ YG+ + +C G+ L G + C ++G W+
Sbjct: 2552 TCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
Query: 2639 SETR--CLAGHCG-----------------------------------IPELIVNG---- 2657
+ R C CG + E + NG
Sbjct: 2612 GDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSG 2671
Query: 2658 -------------------QVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQL 2698
+ G+ + YRDTVVYQCNPGFRL+G+SVRIC QDH WSGQ
Sbjct: 2672 SETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
Query: 2699 PSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPM 2758
P CVP++CGHPG+P +G T+G+ FN NDVV F+CN GYL+QG ++AQC++N QWS P P
Sbjct: 2732 PVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT 2791
Query: 2759 CKVVNCSDPGIPANSKRESKIEH-GNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKP 2817
C+VVNCSDPG N+ R + +F YG + Y C G++L GSS L C NG WD+
Sbjct: 2792 CRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRS 2851
Query: 2818 LPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQP 2877
LP+C+ I CGHPGVP NAVL+GE +T+G+ VHYSC G SL+G +R CQ + HWSG+ P
Sbjct: 2852 LPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALP 2911
Query: 2878 HCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQ 2937
HC+G+ G CGDPGTP HGSR +F+TKS +R++C+ G+ L GS ERTCL NGSW+G Q
Sbjct: 2912 HCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQ 2971
Query: 2938 PECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLP 2997
P C+AV CGNPGT NG + DG FSSSVIY+C EGY SG R CTANGTW+GT P
Sbjct: 2972 PVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAP 3031
Query: 2998 NCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3057
+CTIISCGDPG ANG+++G D+ + VSY C PGY ME S CT +G W+ P
Sbjct: 3032 DCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKP 3091
Query: 3058 TCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117
C+AV CP PP + NG +EG++F WG SISY C GY+LS A+L+C G G W GE+PQC
Sbjct: 3092 VCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQC 3151
Query: 3118 LPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIE 3177
LP FCGDPGIPA+G+ GKSF Y+SEV F C PFILVGSS R+CQADGTWSG P CI+
Sbjct: 3152 LPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCID 3211
Query: 3178 PTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3237
P +C +PG P G QN++ G++VGS V F C+KG+ +QGSTTRTCL +LTWSGIQ EC
Sbjct: 3212 PAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTEC 3271
Query: 3238 IPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3297
IPH+C+QPETPAHA+V +DLP+ GYTL+YTC PGFFLAGG+EHR C++D WTGK P+C
Sbjct: 3272 IPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
Query: 3298 EAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTG 3357
++ K R T + K VP DVF N +WKG Y + G++QP TLTV FNA++
Sbjct: 3332 KS------KGVREVNETVT-KTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSS 3384
Query: 3358 RVNATLSN-SNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEP 3416
+VNAT S S +EL L+G+YK +EA L+L+ + IK A V K + +NW +DG+VS+
Sbjct: 3385 KVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGL 3444
Query: 3417 DGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFA 3476
+ + FQG I GKD+G+F L+R ++ +SS+ HGT+S SVA AILVPFFALI +
Sbjct: 3445 ERGGFTFQGDIHGKDFGKFKLERQD-PLNPDQDSSSHYHGTSSGSVAAAILVPFFALILS 3503
Query: 3477 GFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCT 3536
GF FYLYK RT PK QY G + HEN+NGQA+FENPMYDTN K E KAVRFD LNTVCT
Sbjct: 3504 GFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCT 3563
Query: 3537 MV 3538
+V
Sbjct: 3564 VV 3565
Score = 1492 bits (3863), Expect = 0.0
Identities = 998/3058 (32%), Positives = 1470/3058 (48%), Gaps = 239/3058 (7%)
Query: 440 KVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTL 499
K + CG +QGP+GT SP FP Y + A C W+I N+ IQ++F F LE +D L
Sbjct: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
Query: 500 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 559
++ DG V L+G +P IVS S + L TD +V + GFK Y+ + +
Sbjct: 87 SVYDGQPQQGNLKVR--LSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
Query: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPICIF 615
CG+PG L G+ G F+ D +R+ C G+ L G + C W P C
Sbjct: 145 CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
Query: 616 --PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 673
C ++ SP +P Y NN +C WTI+++PG I L F DF LE +DFL +
Sbjct: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
Query: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN---------- 723
++P TG +PS + S+ + LRL F +D + +GFN +
Sbjct: 265 SGTEAPSI----WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
Query: 724 ----------------------TFGHNECPDPGIPINARRFGDNF-QLGSSISVICEEGF 760
+ CPDPGIP N RR G +F ++G+++ CE+ +
Sbjct: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNY 380
Query: 761 IKTQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCE 818
+ QG+++ITC + + WS P C A CG + PSGVI SP +P Y+D+ +C
Sbjct: 381 V-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Query: 819 WVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNL--LSPLLGSYNGTQVPQFLFSSSN 875
WVI +P IK+ FE F+ E YD L V D + +L G+ VP + S SN
Sbjct: 440 WVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
Query: 876 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 935
++L +D+S + GFK Y+ + C DPGIP +G+R G F G T++F C +
Sbjct: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKG--GCGDPGIPAYGKRTGSSFLHGDTLTFECPAA 557
Query: 936 YRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV 995
+ L E + C++N+ WS P+C C + SG ILSP YPE Y N++NC W +
Sbjct: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
Query: 996 THGKGVQFNFHTFHLEDHHDYLLITENG-SFTQPLARLTGSDLPPTINAGLYGNFRAQLR 1054
G + F+ F +E D+L + ++G S L +G+++P + + +L
Sbjct: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIVRLE 674
Query: 1055 FISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGT 1113
F SD S + GFNIT++ + C DPGIP G R G F +G +++F C G+ + +G+
Sbjct: 675 FQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGS 734
Query: 1114 SEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAG 1172
I C L G VWS+ +PRC A CG T + G++L P +P Y+++ C + I+ + G
Sbjct: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
Query: 1173 KGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDT 1231
I I+ F D L++ DG ++ L+G + G L ST N ++L F +D
Sbjct: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQF-LISTGNFMYLLFTTDN 853
Query: 1232 EGTDEGFQLVYTS--FELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSL 1288
+ GF + Y S E C DPGIP G++ G F ST+ + C+PGYTL
Sbjct: 854 SRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEP 911
Query: 1289 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1348
L C + W++ LPSC A CGG +G+ SG +LSPG+P Y N+L C W IEV G
Sbjct: 912 LVCERNHQ--WNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHGKG 968
Query: 1349 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL---NIVTIQFDTDF 1405
V + F F E+SHD L + + ++ + + ++GS++P I + L ++F +DF
Sbjct: 969 VQMIFHTFHLESSHDYLLITEDGSFSEPVAR-LTGSVLPHTIKAGLFGNFTAQLRFISDF 1027
Query: 1406 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCI 1465
IS GF I FS C DPGVP R G GD++ F C GY L+G ++TC+
Sbjct: 1028 SISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCL 1087
Query: 1466 QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1525
R W P C+A CG ++ G+ G +LSPNFP Y ++ +C + I A I L
Sbjct: 1088 G-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLR 1146
Query: 1526 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI-ESSSNTMHLAFRSDGSVSYTG 1584
SF + D L +YDG DS+S +G+F ++L I S+SN + L F ++GS + G
Sbjct: 1147 TRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQG 1205
Query: 1585 FHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYY-CDAGYVLQGYSTLTCIMGDDG 1643
F L Y + C DPG G R+ + TV Y C+ GY + G +TLTC+ GD
Sbjct: 1206 FQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD-- 1263
Query: 1644 RPGWNRALPSCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVF 1702
R W++ LPSC A CG + + G +LSP YP Y +C + I + F+
Sbjct: 1264 RRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIV 1323
Query: 1703 FQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHF 1761
F T + HD+++V+DGP LL SGS E + S+ N +T++F S I+ GF
Sbjct: 1324 FDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSGFSI 1382
Query: 1762 VYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1821
+ + + C+ P+ G R G+ G +V F C+PGY L G I C + N
Sbjct: 1383 QFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRF 1439
Query: 1822 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFA 1881
W PTCI CGG LT G ILSP YP+PY C W++ V I + SF
Sbjct: 1440 F-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
Query: 1882 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 1941
E ++D L Y+G D+N+P +GSY G+ P + S+ N+L+L F+SD SV +GF +E+
Sbjct: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
Query: 1942 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYP 1999
++C +P +G ++G + +G +++QCD GY + S ITC+ G + W+
Sbjct: 1559 EKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQV 1618
Query: 2000 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2059
+P C A CGG + GV+LSP +P NY + C ++I +P F V QF F T ++D
Sbjct: 1619 LPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALND 1677
Query: 2060 YLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY--- 2115
E+ G+ + ++ LSG +L +T+++ L F + + +GFH VYQA
Sbjct: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
Query: 2116 ---QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNH 2170
Q S P+PR R IG++F+ G + FEC PGY L G++AL C + WN
Sbjct: 1738 SDTQCSSVPEPRYGRR---IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
Query: 2171 PLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY 2230
+P C C GN T GTI SPGYP+ Y N +C W + V G+GI I TE +
Sbjct: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
Query: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLR 2289
D + + DG D +P++G FSG T + STSNQ+ + F SD + + F L Y L
Sbjct: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
Query: 2290 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
CQ P N+ + D + + D++ +QC PG+TL G + ++C G + + P+C
Sbjct: 1915 ACQEPALPSNS--IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
Query: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2409
C L GVILSPG+P SYPN C W IS+ GY + F TE D L+
Sbjct: 1973 ATCGGTLSTLG--GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
Query: 2410 VYDGPNIQSPVLISLSG-DYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYC-ST 2467
+ +GP SP++ SG D +A + S HE + + +DH N++GF++ Y A+ +
Sbjct: 2031 IQNGPYHTSPMIGQFSGTDLPAA--LLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
Query: 2468 PESPP--HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHA-WDAPVPACQ 2524
P+ PP +GY+I+ + + V + C G+ L+G C+ +G + W+ P P C
Sbjct: 2089 PDPPPFQNGYMIN-SDYSVGQSVSFECYPGYILIGHPVLTCQ---HGINRNWNYPFPRCD 2144
Query: 2525 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKEL-TTAVCQSDGTWSNHNKTP 2583
A CG NG I + + D Y + + V G + N
Sbjct: 2145 A-PCGYNVTSQNGTIYSPGF----------PDEYPILKDCIWLITVPPGHGVYINFTLLQ 2193
Query: 2584 RCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
V + P+ N G+TA+ T V S+G +
Sbjct: 2194 TEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHA 2253
Query: 2644 L-AGHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQ--QDHNWSGQL 2698
C P + +++ E+ + D V YQC+PG+ L+G+ + C+ + G L
Sbjct: 2254 FQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSL 2313
Query: 2699 PSC---------------VPVSCGHPGSPIYGRTSGNGF----NFNDVV---TFSCN--- 2733
P+C V +S G+PG+ +T N+N + TF
Sbjct: 2314 PTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQF 2373
Query: 2734 ------IGYLMQGPTKAQCQANR-QWSHPPPMCKVVNCSDPGIPANSKRESKIEHG---- 2782
G Q P N + S+ + A SK+ KI +
Sbjct: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYC 2433
Query: 2783 ------------NFTYGTV---VFYDCNPGYFLFGSSVLICQPNG----QWDKPLPECIM 2823
N T G V V Y C PGY + G S C+ N QWD P C
Sbjct: 2434 SLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQA 2493
Query: 2824 IDCGHPGVPPNAVLSGEKYTFGSTVHYSCTG--KRSLLGQSSRTCQLNGHWS--GSQPHC 2879
+ CG P P N +G ++T S V Y C K Q++ CQ +G WS G P C
Sbjct: 2494 VSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTC 2553
Query: 2880 SGDATGTCGDPGTPGH-------GSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 2932
A + + H GS E + V +C GY L G C ANG+
Sbjct: 2554 KPVACPSI-EAQLSEHVIWRLVSGSLNEYG----AQVLLSCSPGYYLEGWRLLRCQANGT 2608
Query: 2933 WT--GRQPECKAVQCGNPGTTANG-KVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTAN 2989
W +P C+ + CG+ NG K+ + T + ++ I++C GY L G VR+C AN
Sbjct: 2609 WNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATAIFTCNTGYTLVGSHVRECLAN 2666
Query: 2990 GTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN 3049
G WSG+ C CG P NG GD + V Y C PG+ L G+ +R C +
Sbjct: 2667 GLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGF--RLVGTSVRICLQD 2724
Query: 3050 GTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT 3109
WSG P C +TC P ++G G+ F+ +++ C+ GY L + C NG
Sbjct: 2725 HKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ 2784
Query: 3110 WSGEVPQCLPKFCGDPGIPAQGKREG-----KSFIYQSEVSFSCNFPFILVGSSTRICQA 3164
WS +P C C DPG R G +SF Y + + C F L+GSS C A
Sbjct: 2785 WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMA 2844
Query: 3165 DGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTC 3224
+G W S P C+ SC +PGVP + F G+VV + C+ L G+ TR C
Sbjct: 2845 NGLWDRSLPKCL---AISCGHPGVPANAVLTGEL-FTYGAVVHYSCRGSESLIGNDTRVC 2900
Query: 3225 LPDLTWSGIQPECI---PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEH 3281
D WSG P C P C P TPAH + +G D + L ++C+ G L G E
Sbjct: 2901 QEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKS-LLRFSCEMGHQLRGSPE- 2958
Query: 3282 RVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDD--VFAQNYI---WKG 3334
R C + +W+G P+CEA + +P GTP+ + V D +F+ + I W+G
Sbjct: 2959 RTCLLNGSWSGLQPVCEA---VSCGNP----GTPTNGMIVSSDGILFSSSVIYACWEG 3009
Score = 1382 bits (3576), Expect = 0.0
Identities = 938/2924 (32%), Positives = 1372/2924 (46%), Gaps = 280/2924 (9%)
Query: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
+++C +G I SP +P Y N NC W+II+E +RI ++F F +E ++D+L++
Sbjct: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
Query: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
D +G +P + S+ + L SD + + GF + Y + C +P
Sbjct: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDP 701
Query: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
G+P G +G RF +G + + C G++ G +TCI N W VP C A
Sbjct: 702 GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVV-WSSTVPRCEA--P 758
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE-- 298
CGG + SSG+I P +P Y ++ C W I A+PG +I + F FQ E YD LE+
Sbjct: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
Query: 299 --GSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
S P G P +IS N++ L F TD++ GF Y+
Sbjct: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE------------- 865
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
+ S+ C DPG P NG R G DF + STV FSCD Y L
Sbjct: 866 -----------------SVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSD 908
Query: 417 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 476
+ + C+R + W+ P C CG +QG SGT SP FP Y ++ C W I
Sbjct: 909 DEPLVCERNHQ----WNHALPSCDA-LCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI-E 962
Query: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLI---VSMSSQM 533
V+ K +Q+ F F LE +D L I + G +P + LTGS +P I + +
Sbjct: 963 VSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEP---VARLTGSVLPHTIKAGLFGNFTA 1019
Query: 534 WLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELI 593
L +D S+ GF + + E + E C DPG P + R G F D L F C G+ L
Sbjct: 1020 QLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLE 1079
Query: 594 GEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDP 651
G + C + WSA +P C+ C ++ GT+LSP++P Y NN CI+ I ++
Sbjct: 1080 GATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEA 1139
Query: 652 GSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPS-HLTSNSHILRLEFQAD 710
G IHL F L + D L V DG S LGTFT E+ L S S+ L LEF +
Sbjct: 1140 GKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTN 1198
Query: 711 HSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVI-CEEGFIKTQGTETI 769
S + +GF +TY +F +C DPGIP R D ++ + C G+ G+ T+
Sbjct: 1199 GSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGY-AMHGSNTL 1257
Query: 770 TCILMDGKVMWSGLIPKCGAPCGGHF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
TC+ D +V W +P C A CGG +A SG ILSPG+P Y ++L+C W+IEA+PG +
Sbjct: 1258 TCLSGDRRV-WDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKT 1316
Query: 829 IKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
I + F F TE+ +D+L+V DGP LL ++G+ +P+ + S+ N + L F +D S
Sbjct: 1317 ISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFIS 1376
Query: 889 NNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC-- 946
+GF I + + T C DPG+P +G RYG G TV+F CD GY+L + + C
Sbjct: 1377 KSGFSIQFSTSIAAT--CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQ 1434
Query: 947 -EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
+W PTC A CGG++ GP+G ILSP YP+ YP C W V V + F
Sbjct: 1435 LNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIF 1494
Query: 1006 HTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1064
+F++E +D+L I E PL GS P I + F L F SD S+
Sbjct: 1495 KSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLF---LAFRSDASVGLS 1551
Query: 1065 GFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG--G 1122
GF I F E E C DPG G+R+G +F +G T+T+ C SGY++ S I C+ G G
Sbjct: 1552 GFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADG 1611
Query: 1123 RRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF 1182
+ W LP C A CG T +EG++LSPNYP NY C+YSI V + F
Sbjct: 1612 KPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYF 1671
Query: 1183 HLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
A D+ +++DG LL + +G+ +TSNQ+ L F++ + + GF VY
Sbjct: 1672 QTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVY 1731
Query: 1243 TSFEL---SHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMT--GERR 1297
+ + C P++G +I + AGS + + CNPGY L GS+ L C +
Sbjct: 1732 QAVPRTSDTQCSSVPEPRYGRRIGSE-FSAGSIVRFECNPGYLLQGSTALHCQSVPNALA 1790
Query: 1298 AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD 1357
W+ +PSC+ C G F + G ILSPGYP PY NNL C+W I V G+ + +Q ++F
Sbjct: 1791 QWNDTIPSCVVPCSGNFT-QRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFA 1849
Query: 1358 TEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFS 1417
TE + D L + DG L SG+ +P ++ST N + + F +D ++ +GF +++
Sbjct: 1850 TEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYK 1909
Query: 1418 SSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1477
+ AC++P +P N + GD D + FQC+PGY LQG I+C+ R + PS
Sbjct: 1910 TVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPS- 1968
Query: 1478 PVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDF 1537
P+CIA CGG L+ G ILSP FP YP++ DC W I++ Y + F++FS E N+DF
Sbjct: 1969 PLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF 2028
Query: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
L I +GP SP+IG F + LP + S+++ + F SD S + GF L Y+A ++C
Sbjct: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
Query: 1598 FDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1657
DP NG + DY +G +V++ C GY+L G+ LTC G + WN P C AP
Sbjct: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGIN--RNWNYPFPRCDAP 2146
Query: 1658 CGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT-SLHDVVEVYDG 1716
CG T GT+ SP +P Y + +C++ I VP V+ F QT +++D + V+DG
Sbjct: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
Query: 1717 PTQQSSLLSSLSGSHSGESLPLSSGNQITIRF---TSVGPITAKGFHF--VYQAVPRTSS 1771
P Q S L SG+ + E+ SS NQ+ ++F S G FH + + P +
Sbjct: 2207 PDQNSPQLGVFSGNTALET-AYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAV 2265
Query: 1772 TQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
Q + E ++F +G V + C+PGY L G+ + C+ +S Q+ SLPTC
Sbjct: 2266 PQAEMLTE-------DDDFEIGDFVKYQCHPGYTLVGTDILTCKL--SSQLQFEGSLPTC 2316
Query: 1832 IVPC--GGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSL 1889
C + T G ILSPGYP Y N+ C W I V I + V +F +E +D+L
Sbjct: 2317 EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDAL 2376
Query: 1890 DFYDGGDNNAPRLGSYSGT-TIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSC 1948
+ +DG +P L SG T S SN LYL + +D + S GF + Y A S
Sbjct: 2377 EVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA-PYCSL 2435
Query: 1949 PEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGP--VRRWNYPIPICLA- 2005
P + GI VG V + C GY + GHS+ TC P + +W+ P+C A
Sbjct: 2436 THP-LKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV 2494
Query: 2006 QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETI-----HDY 2060
CG S +G F GN +T++ + + H F S++ D
Sbjct: 2495 SCGIPESPGNG-----SFTGN-------EFTLDSKVVYECHEGFKLESSQQATAVCQEDG 2542
Query: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIV--------Y 2112
L G T + + P I + L E ++ S N+ G ++
Sbjct: 2543 LWSNKGKPPTCKPV---ACPSIEAQL----SEHVIWRLVSGSLNEYGAQVLLSCSPGYYL 2595
Query: 2113 QAYQLQSCP--------DPRPF------------RNGFVIGNDFTVGQTISFECFPGYTL 2152
+ ++L C D RP NG IG G T F C GYTL
Sbjct: 2596 EGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTL 2655
Query: 2153 IGNSALTCLHGVSRNWNHPLPRCEA-LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRV 2211
+G+ CL + W+ RC A CG +NG I G+
Sbjct: 2656 VGSHVRECL--ANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFS--------------- 2698
Query: 2212 PPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS 2271
Y + V Q P + + TS +I ++ H
Sbjct: 2699 ------YRDTVVYQCNPGFRLV--------------------------GTSVRICLQDHK 2726
Query: 2272 DFTTSGFFVLSYHAYQLRVCQP---PPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGN 2328
SG Q VC P P A T EF + D++ + C G+ L G
Sbjct: 2727 ---WSG---------QTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
Query: 2329 AILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPN----LQMCAWSI 2384
+ CR Q P C+V+ ++ +++ +P+S+ L C
Sbjct: 2775 SRAQCR--SNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGF 2832
Query: 2385 SVEKGYNITMFVEFFQTEKEFDVLQVYDG-PNIQSPVLISLSGD---YSSAFNITSNGHE 2440
+ +T L + G P + P L+G+ Y + + + G E
Sbjct: 2833 YLLGSSALTCMANGLWDRSLPKCLAISCGHPGV--PANAVLTGELFTYGAVVHYSCRGSE 2890
Query: 2441 VFL-----------QWSAD----HGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG--Q 2483
+ WS GNN GF C P +P HG S+ G +
Sbjct: 2891 SLIGNDTRVCQEDSHWSGALPHCTGNN-PGF--------CGDPGTPAHG---SRLGDDFK 2938
Query: 2484 LNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTD 2543
S++R++C+ G +L G C + +W P C+A+SCG P PTNG I+++D
Sbjct: 2939 TKSLLRFSCEMGHQLRGSPERTCLLNG----SWSGLQPVCEAVSCGNPGTPTNGMIVSSD 2994
Query: 2544 -YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKI 2602
L + V Y C +GY+ S L T C ++GTW+ P C +ISCG+ T NG +
Sbjct: 2995 GILFSSSVIYACWEGYKTSG--LMTRHCTANGTWT--GTAPDCTIISCGDPGTLANGIQF 3050
Query: 2603 GTQTSYGSTAIFTCDLGFML--VGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVI 2660
GT ++ T + C+ G+++ V SA C G W+ S+ C A C P + NG V
Sbjct: 3051 GTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVE 3110
Query: 2661 GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN 2720
G ++ + ++ Y C G++L S++ C+ W G++P C+PV CG PG P GR SG
Sbjct: 3111 GSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGK 3170
Query: 2721 GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC---KVVNCSDPGIPANSKRES 2777
F + V F C +++ G ++ CQA+ WS P C C DPG P + S
Sbjct: 3171 SFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNS 3230
Query: 2778 KIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA-V 2836
+ G+ VF+ C GY + GS+ C N W ECI C P P +A V
Sbjct: 3231 S---RGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADV 3287
Query: 2837 LSGEKYTFGSTVHYSCTGKRSLLGQSS-RTCQLNGHWSGSQPHC 2879
+ + TFG T+ Y+C L G S RTC+ + W+G P C
Sbjct: 3288 RAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
Score = 1210 bits (3131), Expect = 0.0
Identities = 747/2164 (34%), Positives = 1103/2164 (50%), Gaps = 106/2164 (4%)
Query: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLY 122
TCG L+G +G I SP +P Y + A+C WVI + ++ I++ F+ F LE YD L++
Sbjct: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVG 470
Query: 123 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
D + LTG +P + S + L L SD ++ + GFK Y+E++ CG+
Sbjct: 471 DAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD 530
Query: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
PG+P G G+ F GD + + C + L G +TC N+ W P C +
Sbjct: 531 PGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN----QWSGNKPSC--VFS 584
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--E 298
C SSGII SP++P EY NN +C W I++EPG I LIF DF +E ++D+L + +
Sbjct: 585 CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDD 644
Query: 299 GSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
G T+ SG +P + S+ + +RL F +D + RGF+ Y
Sbjct: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT------------ 692
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV-LQ 415
N C DPG P NG+R G F LGS+V F CD+ +V Q
Sbjct: 693 --------------------FGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQ 732
Query: 416 GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT 475
G++SITC + + WS P C+ CG +L SG P +P Y + C W+I
Sbjct: 733 GSESITC-ILQDGNVVWSSTVPRCEA-PCGGHLTASSGVILPPGWPGYYKDSLHCEWIIE 790
Query: 476 AVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWL 535
A I+I F+ F E+ YDTL + DG P ++ G+ P ++S + M+L
Sbjct: 791 A-KPGHSIKITFDRFQTEVNYDTLEVRDGPASSSP--LIGEYHGTQAPQFLISTGNFMYL 847
Query: 536 HLQTDESVGSVGFKVNYKEI--EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELI 593
TD S S+GF ++Y+ + E +SC DPG P+ G R G F R + F C G+ L
Sbjct: 848 LFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLS 907
Query: 594 GEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGS 653
++ +VC+ N+QW+ +P C C GTVLSP +P+ Y N+LNC WTI G
Sbjct: 908 DDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGK 967
Query: 654 RIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTS---NSHILRLEFQAD 710
+ + F+ F LES D+L + + S P+ TG+ +P + + + +L F +D
Sbjct: 968 GVQMIFHTFHLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISD 1026
Query: 711 HSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETIT 770
S+S GFNIT++ + C DPG+P +RR G +F +G S++ C G+ + +G +T
Sbjct: 1027 FSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGY-RLEGATKLT 1085
Query: 771 CILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK 830
C L G+ +WS +P+C A CG G +LSP +P Y ++ C + IE E G I
Sbjct: 1086 C-LGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
Query: 831 ITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQ-VPQFLFSSSNFIYLLFTTDNSRSN 889
+ FQ D L+V+DG + S LG++ + + L S+SN ++L F T+ S ++
Sbjct: 1145 LRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTD 1203
Query: 890 NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGST-VSFSCDSGYRLSHEEPLLC-- 946
GF++ Y S + C DPGIP +G R + T V +SC+ GY + L C
Sbjct: 1204 QGFQLTYTS--FDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLS 1261
Query: 947 EKNHWWSHPLPTCDALCGGDVR-GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
W PLP+C A CGG + SG ILSPGYP Y N+L+CTW ++ GK + +F
Sbjct: 1262 GDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHF 1321
Query: 1006 HTFHLEDHHDYLLITENGSFTQPLAR-LTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1064
F E HD L + + + L + +GS LP I++ L+F SDF IS
Sbjct: 1322 IVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNS---LTLQFDSDFFISKS 1378
Query: 1065 GFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG-GGR 1123
GF+I FS C DPG+PQ G+R G + GDT+TF C GY+L+G ++I C+ R
Sbjct: 1379 GFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNR 1438
Query: 1124 RVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1183
W P C+A CG + T G++LSPNYP Y EC + ++V I + ++F+
Sbjct: 1439 FFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
Query: 1184 LAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
+ D L IY+G+D + L+G++ G S + S+ N L+L F SD GF + +
Sbjct: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQG-SQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557
Query: 1243 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGE--RRAWD 1300
C DPG G ++ GSTI Y C+ GY + S + C+ G + +WD
Sbjct: 1558 KEKPREACFDPGNIMNGTRVGTDFKL-GSTITYQCDSGYKILDPSSITCVIGADGKPSWD 1616
Query: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
LPSC A CGG++ G S G +LSP YP Y C++ I V +V QF F T A
Sbjct: 1617 QVLPSCNAPCGGQYTG-SEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-A 1674
Query: 1361 SHDILRVWDGPPENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS- 1418
+D+ ++DG LL +SGS E + +T N + ++F S GF + +
Sbjct: 1675 LNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
Query: 1419 --SVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF-WQP 1475
+ T C P G R G G V F+C+PGY LQG + C V N W
Sbjct: 1735 PRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
Query: 1476 SPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1535
+ P C+ PC GN T G ILSP +P PY ++ +C W I V I + ISF+ E N+
Sbjct: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
Query: 1536 DFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRE 1595
D L I+DG D +P +GSF + +P + S+SN ++L F+SD SV+ GFHLEYK
Sbjct: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
Query: 1596 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH 1655
+C +P N ++G Y + +++ C+ GY LQG S ++C+ G R WN P C
Sbjct: 1915 ACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRR--WNYPSPLCI 1972
Query: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-HDVVEVY 1714
A CG + G +LSP +P +Y +C + I++P + QF+ F T HD +E+
Sbjct: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQ 2032
Query: 1715 DGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQC 1774
+GP S ++ SG+ +L LS+ ++ I F S +GF YQA C
Sbjct: 2033 NGPYHTSPMIGQFSGTDLPAAL-LSTTHETLIHFYSDHSQNRQGFKLAYQAY---ELQNC 2088
Query: 1775 SSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1834
P + G I ++++VG SV F+C PGYIL G + C+ N WN P C P
Sbjct: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGIN--RNWNYPFPRCDAP 2146
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1894
CG +T + GTI SPG+P+ Y +C+W ITVP G G+ + TE D + +DG
Sbjct: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
Query: 1895 GDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSC-PEPQT 1953
D N+P+LG +SG T S++N + L F SD S + F L + A L C P P
Sbjct: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKKCQPPPAV 2265
Query: 1954 PSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC--GGA 2010
P + + D + +GD V +QC GY+L G +TC ++ +P C AQC
Sbjct: 2266 PQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEV 2325
Query: 2011 MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSET 2070
+ SGVILSPG+PGNY +S C+W+I + + + + F +E D LEV GSS
Sbjct: 2326 RTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQ 2385
Query: 2071 STVIGRLSGPQIPSSLF-STTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNG 2129
S ++ LSG S F S +++ L + +D++ +K+GF I Y A C P +NG
Sbjct: 2386 SPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCSLTHPLKNG 2442
Query: 2130 FVIGNDF-TVGQTISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRCEAL-CGGNITA 2185
++ VG + + C PGY ++G+S TC W+ P C+A+ CG +
Sbjct: 2443 GILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESP 2502
Query: 2186 MNGT 2189
NG+
Sbjct: 2503 GNGS 2506
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 4326 bits (11221), Expect = 0.0
Identities = 1997/3536 (56%), Positives = 2556/3536 (72%), Gaps = 136/3536 (3%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
C L G NGT+ESPGFPYGYPN ANCTW I AEE++RIQ+VFQSFALEE++D LS++DG
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
Query: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 184
P P N RTRLTGF LP + S + SLRL SD+AVSA GF YE L S +CGNPG
Sbjct: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
Query: 185 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 244
P G+ G+ F++GDK+RYSC G+ L+GH LTC A S N+A+WDFP+P CRA+DACGGT
Sbjct: 146 PNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGT 205
Query: 245 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 304
+RG SGIISSP FP+EYHNNADCTWTI+AE GDTI+L+F DFQ+E+ YD+LE+ G+E +
Sbjct: 206 LRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSS 265
Query: 305 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNS 364
+W +G ++P P+IS+KNWLRLHF +D NHR RGFSA YQVKK I+ KSRG KL P KDNS
Sbjct: 266 LWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNS 325
Query: 365 NKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQR 424
K S+L + G+ N+CPDPG PE GKR+GSDF LGS+VQF+C+E Y LQG+K ITC +
Sbjct: 326 QKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
Query: 425 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 484
++++FAAWSDHRPVC+ + C ++L+GPSG TSPNFP QYD+NA CVW+ITA+N +KVI+
Sbjct: 386 VSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIK 445
Query: 485 INFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVG 544
+ FEEFDLE GYDTLT+GDGG+ GD +TVL +LTG+ VPDLIVS + QMWL QTD S
Sbjct: 446 LAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGS 505
Query: 545 SVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN 604
S+GFK +Y+EIE+ SCGDPG P YG REG F + D L+FECQ FEL+G+K+I CQ+NN
Sbjct: 506 SLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNN 565
Query: 605 QWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDL 664
QWSA P C+F C NFT+P G VLSP+YPE YGN+L+C+W I++ P SRIHL+FND D+
Sbjct: 566 QWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDV 625
Query: 665 ESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 724
E QFDFL +KDG + E+P+LGTF+G ++PS +TS+ H+ RLEFQ DHS RGFNIT+ T
Sbjct: 626 EPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
Query: 725 FGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 784
F HNECPDPG+P+N +RFGD+ QLGSSIS +C+EGF+ TQG+ETITC+L +G V+W+ +
Sbjct: 686 FRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
Query: 785 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 844
+C APCGGH ++PSG ILSPGWPG+YKD+L+C WVIEA+PG+ IKITF+RF+TE+NYD
Sbjct: 746 LRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDT 805
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 904
LEV DG +PL+G Y+GTQVPQFL S+SN++YLLF+TD S S+ GF++ YE++T+ +
Sbjct: 806 LEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSD 865
Query: 905 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 964
CLDPGIPV+G+R+G+DF +G+ V+FSCDSGY LS EPL CE N WS LP+C+ALCG
Sbjct: 866 HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG 925
Query: 965 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGS 1024
G ++G SGTILSPG+P+FYPN+LNCTW ++ +HGKGV F FHTFHLE HDYLLITENGS
Sbjct: 926 GFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGS 985
Query: 1025 FTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIP 1084
FTQPL +LTGS LP I+AGLYGNF AQ+RFISDFS+SYEGFNITFSEY+LEPCE+P +P
Sbjct: 986 FTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVP 1045
Query: 1085 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNN 1144
Y R G FG+GDTLTFSC GYRLEGT+ I CLGG RR+WS+PLPRCVAECG S T
Sbjct: 1046 AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGT 1105
Query: 1145 EGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLG 1204
+G LLSPN+P+NY NNHECIYSIQ Q GKGI + AR F L++GDVLK+YDG + + LLG
Sbjct: 1106 QGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLG 1165
Query: 1205 AFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISD 1264
F+ + M G+TL+STS+ LWL+F +D E T +GF+L ++SFEL CEDPG P+FGYK+ D
Sbjct: 1166 VFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHD 1225
Query: 1265 QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILS 1324
+GHFAGS++ + C+PGY+L GS L C++GERR WD PLP+C+AECGG +GE SG++LS
Sbjct: 1226 EGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLS 1285
Query: 1325 PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS 1384
PGYP PY++NL C+W IE + G + L FL FDTE HD+LR+WDGP E+ +LLKE+SG
Sbjct: 1286 PGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGP 1345
Query: 1385 LIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGD 1444
+P+ +HST N V +QF TDF+ SK GFAIQFS S AT+C DPG+P NG+R+GD E GD
Sbjct: 1346 ALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGD 1405
Query: 1445 TVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPY 1504
+ VFQCDPGY LQG I+C+++ENR+FWQPSPP CIAPCGG+LTG SG ILSPN+P PY
Sbjct: 1406 STVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPY 1465
Query: 1505 PHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE 1564
P ++CDW +TV+ DYVI+L F F++EP YDFL+IYDG DS SPLIGSF S+LP RIE
Sbjct: 1466 PPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIE 1525
Query: 1565 SSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCD 1624
SSSN++ LAFRSD SVS GF ++Y RESCFDPG+I NGTR+G D KLGS+VTYYC
Sbjct: 1526 SSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCH 1585
Query: 1625 AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC 1684
GY ++G STL+CI+G DG+P WN P C APCG + GS+G VLSPNYP+NY+ G C
Sbjct: 1586 GGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQIC 1645
Query: 1685 VYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI 1744
+Y + VPK++VVFGQF FF T+L+DVVEV+DG +Q S LLSSLSGSH+GESLPL++ NQ+
Sbjct: 1646 LYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQV 1705
Query: 1745 TIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGY 1804
I+F++ G A+GFHFVYQAVPRTS+TQCSSVPEPR+G+R+G++F+VG+ V F+CN GY
Sbjct: 1706 LIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGY 1765
Query: 1805 ILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWK 1864
L GS I C VP +LAQWN S PTC+VPCGG LT+R+GTILSPG+PEPY N+LNCVWK
Sbjct: 1766 ALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWK 1825
Query: 1865 ITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLN 1924
I VPEGAGIQ+QVVSF TE NWDSL+ +DG DN LGS+SGTT+P LLNSTSN LYL+
Sbjct: 1826 IVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLH 1885
Query: 1925 FQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 1984
F SDISVSAAGFHLEY +GL SCPEP PS+G+K G+RY+V DVVSFQC+ GY+LQGH+
Sbjct: 1886 FYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHA 1945
Query: 1985 HITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFG 2044
HI+CMPG VRRWNYP P+C+AQCGG + + GVILSPGFPGNYPS++DC+W I LP+GFG
Sbjct: 1946 HISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFG 2005
Query: 2045 VHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQN 2104
H+QF+NFSTE HDY+E+R+G ETS ++GR SG ++PSSL ST+HET++YFHSD+SQN
Sbjct: 2006 AHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQN 2065
Query: 2105 KQGFHIVYQ------------------------------------------AYQLQSCPD 2122
+ GF + YQ AY+LQ CPD
Sbjct: 2066 RPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPD 2125
Query: 2123 PRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGN 2182
P PF NG V G + VGQ+++FEC PGY L G+ LTC HG +RNW+HPLP+CE CGGN
Sbjct: 2126 PEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGN 2185
Query: 2183 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2242
IT+ NGT+YSPG+P Y + QDC WL+ VP G+G+ +N ++LQTEP DFIT+WDGP Q
Sbjct: 2186 ITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQT 2245
Query: 2243 SPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEI 2302
+P++G F+ + A ++V S+SNQ+L+KFH D T G F +++ AY L C PP +PNAE+
Sbjct: 2246 APRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEV 2305
Query: 2303 LTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDST 2362
+TE++EF IGDI+RY+CLPGFTLVGN ILTC+LG LQ +G PP+C+V CP NEL DST
Sbjct: 2306 VTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDST 2365
Query: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLI 2422
GVILS YP SYP Q C+W + VE YNI++ VE+F +EK++D +++DGP+ QSP+L
Sbjct: 2366 GVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLK 2425
Query: 2423 SLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2482
+LSG+YS+ +TS+ + V+L
Sbjct: 2426 ALSGNYSAPLIVTSSSNSVYL--------------------------------------- 2446
Query: 2483 QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGIL-T 2541
RW+ D + G + AP C +P+AP +G IL
Sbjct: 2447 ------RWSSDHAYNRKGFKIR-----------YSAPY-------CSLPRAPLHGFILGQ 2482
Query: 2542 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNK 2601
T G + + CN GYRL + G P C +SCG P NG
Sbjct: 2483 TSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMV 2542
Query: 2602 IGTQTSYGSTAIFTCDLGFMLVGSA--VRECLSSGLWSESET--RCLAGHCGIPEL---- 2653
G + + G+ A+++C G+ L A ECL +GLWS +C+ C P++
Sbjct: 2543 FGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTC--PDVSSIS 2600
Query: 2654 IVNGQ---VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWS--GQLPSCVPVSCGH 2708
+ +G+ + Y ++ ++ C+PG+ G V CQ + WS P+C +SCG
Sbjct: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGE 2660
Query: 2709 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPG 2768
P G G + FSCN GY + G +C AN WS C +C P
Sbjct: 2661 LPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPE 2720
Query: 2769 IPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH 2828
N I N++Y V Y CN G+ L G SV ICQ + W P C+++ CGH
Sbjct: 2721 PIVNGH----INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGH 2776
Query: 2829 PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCG 2888
PG PP++ +SG+ YT G+ V YSC GKR+L+G S+R C L+GHW+GS PHCSG + G CG
Sbjct: 2777 PGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCG 2836
Query: 2889 DPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNP 2948
DPG P HG R +F + +R++C+ G++L GS ERTC ANGSW+G QPEC + CGNP
Sbjct: 2837 DPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNP 2896
Query: 2949 GTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPG 3008
GT +N +V DG FSSS++Y C EGY +G R C+ NGTW+G+ P C +I+CGDPG
Sbjct: 2897 GTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPG 2956
Query: 3009 IPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPP 3068
IPANGLR G+D+ + V+Y C PGY ME + + +CT + TW+G P C+A+ C PP
Sbjct: 2957 IPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPP 3016
Query: 3069 QISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIP 3128
I NG++ G++F WG S++Y C GY+LS PAV TC GNG+W+GE+PQC P FCGDPG+P
Sbjct: 3017 LIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVP 3076
Query: 3129 AQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV 3188
++G+RE + F Y+S VSFSC+ P +LVGS R CQ+DGTWSG+ P CI+PT T+C +PGV
Sbjct: 3077 SRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGV 3136
Query: 3189 PRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETP 3248
P+ G QNN+ G+QVGS V F C+KG+LLQGSTTRTCLP+LTWSG P+C+PH C+QPETP
Sbjct: 3137 PQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETP 3196
Query: 3249 AHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC----EAGSKIL 3304
HANV +DLPS GYTLIY+CQ GF L GG+EHR C++D +WTGK PIC +G I
Sbjct: 3197 THANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI- 3255
Query: 3305 VKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT-L 3363
A P + +P DVFA+N +WKG+Y ++G+KQP L VT F + +VNAT +
Sbjct: 3256 ----NTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMI 3311
Query: 3364 SNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVF 3423
+S +EL L+G YK ++ L+L++Y I P + K K+++WA+DG VS+E GAT+++
Sbjct: 3312 DHSGVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIY 3371
Query: 3424 QGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPH-GTNSSSVAIAILVPFFALIFAGFGFYL 3482
QG ++G+ +GQFG QRL L + E S H +NSSSVA AILVPF ALI AGF YL
Sbjct: 3372 QGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYL 3431
Query: 3483 YKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
YK R PK + G + HEN N +A FENPMYD N + + A + ++TVCT V
Sbjct: 3432 YKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
Score = 1543 bits (3995), Expect = 0.0
Identities = 1013/3115 (32%), Positives = 1490/3115 (47%), Gaps = 306/3115 (9%)
Query: 435 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 494
H P + C L GP+GT SP FP+ Y + A C W ITA ++ IQ+ F+ F LE
Sbjct: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
Query: 495 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 554
+D L++ DG P + LTG +P IVS ++ + L L +D +V + GF Y+
Sbjct: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
Query: 555 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANI 610
+ +CG+PG GI++G F+ D +R+ C GF L G + C ++ W +
Sbjct: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
Query: 611 PICIFP--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQF 668
P C C G + SP +P Y NN +C WTI+++ G I L F DF LE +
Sbjct: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
Query: 669 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN----- 723
DFL V + FTGA +P+ + S+ + LRL F +D + RGF+ Y
Sbjct: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
Query: 724 ---------------------------TFGHNECPDPGIPINARRFGDNFQLGSSISVIC 756
+ GHN CPDPGIP +R G +F+LGSS+ C
Sbjct: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
Query: 757 EEGFIKTQGTETITCI-LMDGKVMWSGLIPKCGAP-CGGHFSAPSGVILSPGWPGYYKDS 814
EG+ QG++ ITC+ + D WS P C A C H PSG+I SP +P Y ++
Sbjct: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
Query: 815 LNCEWVIEA-EPGHSIKITFERFQTELNYDVLEVHDG--PNLLSPLLGSYNGTQVPQFLF 871
+C W+I A P IK+ FE F E YD L V DG +L GT VP +
Sbjct: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
Query: 872 SSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFS 931
S+++ ++LLF TD S S+ GFK YE + SC DPGIP +GRR G F G T+ F
Sbjct: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQG--SCGDPGIPAYGRREGSRFHHGDTLKFE 546
Query: 932 CDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTW 991
C + L ++ + C+KN+ WS P C C + PSG +LSP YPE Y N L+C W
Sbjct: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
Query: 992 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFR 1050
+ + F+ +E D+L+I + + P L +G+ LP +I +
Sbjct: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS---GHV 663
Query: 1051 AQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR- 1109
A+L F +D S GFNITF+ + C DPG+P G R G + +G +++F C G+
Sbjct: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
Query: 1110 LEGTSEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQ 1168
+G+ I C L G VW++ + RC A CG T+ G +LSP +P Y++ C + I+
Sbjct: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
Query: 1169 VQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEF 1227
Q G I I+ F D L++ DG+ + L+G + G + L STSN L+L F
Sbjct: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQF-LISTSNYLYLLF 842
Query: 1228 NSDTEGTDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1285
++D +D GFQL Y + L HC DPGIP G + + + G+ + + C+ GYTL
Sbjct: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGND-FYVGALVTFSCDSGYTLSD 901
Query: 1286 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1345
L+C + W LPSC A CGG +G SSG ILSPG+P Y NNL C W+IE
Sbjct: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQG-SSGTILSPGFPDFYPNNLNCTWIIETSH 958
Query: 1346 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFD 1402
G V F F E+ HD L + + L ++++GS +P I + L ++F
Sbjct: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFI 1017
Query: 1403 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERI 1462
+DF +S GF I FS C +P VP R G GDT+ F C PGY L+G RI
Sbjct: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
Query: 1463 TCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI 1522
TC+ R W P C+A CG ++TG+ G +LSPNFP Y ++ +C ++I I
Sbjct: 1078 TCLGGRRR-LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
Query: 1523 SLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVS 1581
L +F + D L +YDG ++++ L+G F S++ + S+S+++ L F +D +
Sbjct: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
Query: 1582 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMD-YKLGSTVTYYCDAGYVLQGYSTLTCIMG 1640
GF L + + C DPG G ++ + + GS+V++ CD GY L+G L C+ G
Sbjct: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
Query: 1641 DDGRPGWNRALPSCHAPCGSRSTGS-EGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1699
+ R W+R LP+C A CG G G VLSP YP Y NC+++I +
Sbjct: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
Query: 1700 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1758
F+ F T +HDV+ ++DGP + LL LSG + L S+ N + ++F++ + +G
Sbjct: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
Query: 1759 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1818
F + +++T C+ P+ G R G+ + G S +F C+PGY L GS I C +
Sbjct: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
Query: 1819 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1878
N W S PTCI PCGG LT G ILSP YPEPY C WK+TV I +
Sbjct: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
Query: 1879 SFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHL 1938
F E +D L YDG D+ +P +GS+ G+ +P + S+SN+L+L F+SD SVS AGF +
Sbjct: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
Query: 1939 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--W 1996
+YT +SC +P + +G ++G +G V++ C GY ++G S ++C+ GP + W
Sbjct: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
Query: 1997 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2056
N P P+C A CGG GV+LSP +P NY S C + + +P + V QF F T
Sbjct: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHT-A 1667
Query: 2057 IHDYLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY 2115
++D +EV G S+ S ++ LSG SL +T+++ + F + +GFH VYQA
Sbjct: 1668 LNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
Query: 2116 ------QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH--GVSRN 2167
Q S P+PR G +G+DF+VG + FEC GY L G+ + CL G
Sbjct: 1728 PRTSATQCSSVPEPR---YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
Query: 2168 WNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTE 2227
WN P C CGGN+T GTI SPG+P+ Y N +C W + VP G GI I TE
Sbjct: 1785 WNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTE 1844
Query: 2228 PIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAY 2286
+D + V+DG D +G FSG T + STSNQ+ + F+SD + S F L Y
Sbjct: 1845 QNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
Query: 2287 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2346
L C P P VP+ + T + + + D++ +QC PG+ L G+A ++C G + + PP
Sbjct: 1905 GLSSC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
Query: 2347 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2406
+C C ++ GVILSPG+P +YP+ C+W I++ G+ + F TE D
Sbjct: 1963 LCIAQCGGTVEEME--GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHD 2020
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
+++ +GP S ++ SG + ++ S HE + + +DH N+ GF++ Y S
Sbjct: 2021 YIEIRNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
Query: 2467 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2526
Q++S + RGF L + WD P C+A
Sbjct: 2080 ---------------HQISSFL-----RGFDLSELERTNSTPPVAASYVWDLD-PGCEAY 2118
Query: 2527 ---SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2583
C P+ NG + Y VG VT+ C GY+L+ + T ++ W + P
Sbjct: 2119 ELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLP 2176
Query: 2584 RCVV-----------------------------------------ISCGELPTPPNGNKI 2602
+C V ++ L T P+G+ I
Sbjct: 2177 KCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFI 2236
Query: 2603 ----GTQTSYGSTAIFTCDLGFMLVGSAV--------RECLSSGLWSESETRCLAGHCGI 2650
G Q + +FT + V S+ R+ + G+++ + + C
Sbjct: 2237 TIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPP 2296
Query: 2651 PELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSC----- 2701
P ++ N +V+ EN + D V Y+C PGF L+G+ + C+ + G P C
Sbjct: 2297 PTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCP 2356
Query: 2702 ----------VPVSCGHPGS---------------------------------------- 2711
V +S +PGS
Sbjct: 2357 TNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDG 2416
Query: 2712 -----PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSD 2766
P+ SGN ++ +VT S N YL A + + + P C +
Sbjct: 2417 PSGQSPLLKALSGN-YSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPL 2475
Query: 2767 PGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ----WDKPLPECI 2822
G G + + CN GY L G S+ IC + Q W + +P C
Sbjct: 2476 HGFILGQTSTQP--------GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ 2527
Query: 2823 MIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRT--CQLNGHWSGSQ--PH 2878
+ CG P P N ++ G++YT G+ YSC+ L + T C G WS P
Sbjct: 2528 ALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQ 2587
Query: 2879 CSGDATGTCGDPGTPG--HGSRQ---ESNFRTKSTVRYACDTGYILHGSEERTCLANGSW 2933
C TC D + HG + E+ ++ ++ + CD GY G C ANG W
Sbjct: 2588 C---VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKW 2644
Query: 2934 T--GRQPECKAVQCGNPGTTANGKVFRIDG-TTFSSSVIYSCMEGYILSGPSVRQCTANG 2990
+ P C+ + CG NG RI + + ++ I+SC GY L G VR+C ANG
Sbjct: 2645 SLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2702
Query: 2991 TWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTING 3050
WSG+ C CG P NG G++Y +V Y C G+ L G +R C +
Sbjct: 2703 LWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGF--RLIGMSVRICQQDH 2760
Query: 3051 TWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTW 3110
WSG P C V+C P + ++ G ++ G + Y C L + C +G W
Sbjct: 2761 HWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHW 2820
Query: 3111 SGEVPQCLPK---FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGT 3167
+G +P C CGDPGIPA G R G SF + + FSC +L GSS R CQA+G+
Sbjct: 2821 TGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGS 2880
Query: 3168 WSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPD 3227
WSGS P C SC NPG P + + G S + + C++G+ G +R C +
Sbjct: 2881 WSGSQPEC---GVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVN 2937
Query: 3228 LTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRV---- 3283
TW+G PEC+ +C P PA+ +G D + T+ Y C PG+ + HRV
Sbjct: 2938 GTWTGSDPECLVINCGDPGIPANGLRLGNDF-RYNKTVTYQCVPGYMM---ESHRVSVLS 2993
Query: 3284 CRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNF 3338
C D TW G P+C+A L+ P P + P+ K V +++W S +
Sbjct: 2994 CTKDRTWNGTKPVCKA----LMCKPPPLI--PNGK------VVGSDFMWGSSVTY 3036
Score = 1226 bits (3172), Expect = 0.0
Identities = 863/2841 (30%), Positives = 1288/2841 (45%), Gaps = 277/2841 (9%)
Query: 60 GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYL 119
G +++C +G + SP +P Y N +C W+I+A +RI + F +E ++D+L
Sbjct: 573 GCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFL 632
Query: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
+ DG +G LP +TS+ V L +D + GF + + + + C
Sbjct: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAE 238
+PGVP G +G +G I + C G++ G +TC+ + W+ V R E
Sbjct: 693 DPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKE-GSVVWNSAV--LRCE 749
Query: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
CGG + SG I SP +P Y + C W I A+PG I + F F+ E YD LE+
Sbjct: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809
Query: 299 G----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRG 354
S P G +P +IS N+L L F TD +H GF Y+
Sbjct: 810 DGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET---------- 859
Query: 355 FKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVL 414
I S+ C DPG P NG+R G+DF +G+ V FSCD Y L
Sbjct: 860 --------------------ITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
Query: 415 QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVI 474
+ + C E WS P C+ CG +QG SGT SP FP Y +N C W+I
Sbjct: 900 SDGEPLEC----EPNFQWSRALPSCEA-LCGGFIQGSSGTILSPGFPDFYPNNLNCTWII 954
Query: 475 TAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-----DLIVSM 529
+ K + F F LE G+D L I + G P L+ LTGS +P L +
Sbjct: 955 -ETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP---LRQLTGSRLPAPISAGLYGNF 1010
Query: 530 SSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFG 589
++Q + +D S+ GF + + E + E C +P P Y IR+G F D L F C G
Sbjct: 1011 TAQ--VRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPG 1068
Query: 590 FELIGEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 647
+ L G I C + WS+ +P C+ C ++ T GT+LSP++P Y NN CI++I
Sbjct: 1069 YRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSI 1128
Query: 648 ISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPS-HLTSNSHILRLE 706
+ PG I L F+L S+ D L V DG++ + +LG F+ +E+ L S S L L+
Sbjct: 1129 QTQPGKGIQLKARAFEL-SEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLD 1187
Query: 707 FQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQL-GSSISVICEEGFIKTQG 765
F D + +GF + +++F +C DPG P + D GSS+S C+ G+ +G
Sbjct: 1188 FITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGY-SLRG 1246
Query: 766 TETITCILMDGKVMWSGLIPKCGAPCGGHFSAP-SGVILSPGWPGYYKDSLNCEWVIEAE 824
+E + C+ + + W +P C A CGG SG +LSPG+P Y+ +LNC W IEAE
Sbjct: 1247 SEELLCLSGERRT-WDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAE 1305
Query: 825 PGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 884
G +I + F F TE +DVL + DGP LL +G +P+ L S+ N + L F+TD
Sbjct: 1306 AGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTD 1365
Query: 885 NSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPL 944
S GF I + T SC DPGIP +G R G + G + F CD GY L +
Sbjct: 1366 FFTSKQGFAIQFSVSTAT--SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEI 1423
Query: 945 LC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
C E +W PTC A CGGD+ GPSG ILSP YPE YP C W V V+ +
Sbjct: 1424 SCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483
Query: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFS 1060
F+ F+LE +D+L I + PL GS LP I + F L F SD S
Sbjct: 1484 ALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLF---LAFRSDAS 1540
Query: 1061 ISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1120
+S GF I ++E E C DPG + G+R+G + +G ++T+ C GY +EGTS + C+
Sbjct: 1541 VSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCIL 1600
Query: 1121 G--GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINIS 1178
G G+ VW+ P P C A CG ++G++LSPNYP NY + C+Y + V +
Sbjct: 1601 GPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQ 1660
Query: 1179 ARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGF 1238
FH A DV++++DG + + LL + +G+ +TSNQ+ ++F++ GF
Sbjct: 1661 FAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGF 1720
Query: 1239 QLVYTSF---ELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM--T 1293
VY + + C P++G ++ G+ + + CN GY L GS ++C+
Sbjct: 1721 HFVYQAVPRTSATQCSSVPEPRYGKRLGSD-FSVGAIVRFECNSGYALQGSPEIECLPVP 1779
Query: 1294 GERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQF 1353
G W+ P+C+ CGG E G ILSPG+P PY N+L C+W I V G + +Q
Sbjct: 1780 GALAQWNVSAPTCVVPCGGNLT-ERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQV 1838
Query: 1354 LAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFA 1413
++F TE + D L V+DG +L SG+ +P ++ST N + + F +D +S +GF
Sbjct: 1839 VSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFH 1898
Query: 1414 IQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFW 1473
+++ + ++C +P VP NG + G+ D V FQC+PGY LQG I+C+ R W
Sbjct: 1899 LEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRR-W 1957
Query: 1474 QPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEP 1533
PP+CIA CGG + G ILSP FP YP + DC W I + + + F++FS EP
Sbjct: 1958 NYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEP 2017
Query: 1534 NYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY---- 1589
N+D++ I +GP S ++G F S+LP + S+S+ + F SD S + GF LEY
Sbjct: 2018 NHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLT 2077
Query: 1590 --------------------------------------KAKLRESCFDPGNIMNGTRLGM 1611
+A + C DP NG G
Sbjct: 2078 YSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGA 2137
Query: 1612 DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLS 1671
Y +G +VT+ C GY L G+ LTC G + W+ LP C PCG T S GTV S
Sbjct: 2138 GYNVGQSVTFECLPGYQLTGHPVLTCQHGTN--RNWDHPLPKCEVPCGGNITSSNGTVYS 2195
Query: 1672 PNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGS 1730
P +P YS +CV+ I VP V QT D + ++DGP Q + L + S
Sbjct: 2196 PGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRS 2255
Query: 1731 HSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEF 1790
+ +++ SS NQ+ ++F T F + A P T + +P EF
Sbjct: 2256 MAKKTVQ-SSSNQVLLKFHR-DAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTE-NEEF 2312
Query: 1791 AVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPC--GGILTKRKGTILS 1848
+G V + C PG+ L G+ + C+ + Q+ P C V C +LT G ILS
Sbjct: 2313 NIGDIVRYRCLPGFTLVGNEILTCKL--GTYLQFEGPPPICEVHCPTNELLTDSTGVILS 2370
Query: 1849 PGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGT 1908
YP Y C W + V I + V F +E +D + +DG +P L + SG
Sbjct: 2371 QSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGN 2430
Query: 1909 -TIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGD-RYMV 1966
+ P ++ S+SN++YL + SD + + GF + Y+A C P+ P G +G
Sbjct: 2431 YSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLPRAPLHGFILGQTSTQP 2487
Query: 1967 GDVVSFQCDQGYSLQGHSHITCM--PGPVRRWNYPIPICLA-QCGGAMSDFSGVILSPGF 2023
G + F C+ GY L GHS C P W+ IP+C A CG + +G++ +
Sbjct: 2488 GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEY 2547
Query: 2024 PGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIP 2083
+ C+ G HLQ +T D +G V + P
Sbjct: 2548 TVGTKAMYSCS--------EGYHLQAGAEATAECLD-----TGLWSNRNVPPQCVPVTCP 2594
Query: 2084 S-SLFSTTH-ETSLYFHSDYSQNKQ-------GFHIVYQ------------------AYQ 2116
S S H L F + Y Q G++ Q +
Sbjct: 2595 DVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCR 2654
Query: 2117 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
+ SC + NG IG G T F C GYTL+G+ C+ + W+ RC
Sbjct: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRCL 2712
Query: 2177 A-LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD---- 2231
A CG +NG I Y C R+ I ++ + Q + +
Sbjct: 2713 AGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRL-----IGMSVRICQQDHHWSGKTP 2767
Query: 2232 FITVWDGPDQNSPQIGQFSGNTALESV---YSTSNQILIKFHSD--FTTSGFFVLSY--- 2283
F + SP Q SG++ YS + + +S G + S
Sbjct: 2768 FCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC 2827
Query: 2284 HAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG 2343
+ VC P +P A + D F+ G ++R+ C G L G++ TC+ G
Sbjct: 2828 SGTSVGVC-GDPGIP-AHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANG--SWSG 2883
Query: 2344 APPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK 2403
+ P C V+ N + V+ S G S + C +GY T +
Sbjct: 2884 SQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYEC------REGYYATGLLSRH---- 2933
Query: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF 2463
S++G + T + E + D G G R+
Sbjct: 2934 ------------------CSVNGTW------TGSDPECLVINCGDPGIPANGLRLGNDFR 2969
Query: 2464 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2523
Y T V + C G+ + +S V S W+ P C
Sbjct: 2970 YNKT--------------------VTYQCVPGYMM--ESHRVSVLSCTKDRTWNGTKPVC 3007
Query: 2524 QAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2583
+A+ C P NG ++ +D++ G+ VTY C +GY+LS + T C+ +G+W+ + P
Sbjct: 3008 KALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFT--CEGNGSWT--GELP 3063
Query: 2584 RCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
+C + CG+ P G + SY S+ F+C +LVGS R C S G WS ++ C
Sbjct: 3064 QCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 3123
Query: 2644 L------AGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQ 2697
+ G+P+ + + Y TV+++C G+ L GS+ R C + WSG
Sbjct: 3124 IDPTLTTCADPGVPQFGIQNN--SQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGT 3181
Query: 2698 LPSCVPVSCGHPGSPIYGRTSGNGF-NFNDVVTFSCNIGYLMQGPTKAQ-CQANRQWSHP 2755
P CVP C P +P + + + +SC G+ ++G ++ + C+A+ W+
Sbjct: 3182 PPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGK 3241
Query: 2756 PPMCKVVNCSDPGIPANSKRE 2776
PP+C V S G P N+ RE
Sbjct: 3242 PPICLEVRPS--GRPINTARE 3260
Score = 935 bits (2417), Expect = 0.0
Identities = 689/2370 (29%), Positives = 1068/2370 (45%), Gaps = 267/2370 (11%)
Query: 953 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1012
SH + C + GP+GT+ SPG+P YPN NCTWT+ +Q F +F LE+
Sbjct: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
Query: 1013 HHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
D L + + + L RLTG LP TI + LR ISD+++S +GF+ T+
Sbjct: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATI---VSAATTLSLRLISDYAVSAQGFHATYE 132
Query: 1072 EYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR--VWSAP 1129
C +PG G + G F +GD + +SC+ G+ LEG + + C G W P
Sbjct: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
Query: 1130 LPRCVAE--CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1187
LP C A+ CG + GI+ SP++P Y NN +C ++I + G I + F L G
Sbjct: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
Query: 1188 -DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY---T 1243
D L++ + + FTGAS+ +SS N L L F SD GF Y
Sbjct: 253 YDFLEVTGTEGSSLW----FTGASLPAPVISS-KNWLRLHFTSDGNHRQRGFSAQYQVKK 307
Query: 1244 SFEL-----------------------------SHCEDPGIPQFGYKISDQGHFAGSTII 1274
EL + C DPGIP+ G ++ GS++
Sbjct: 308 QIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL-GSSVQ 366
Query: 1275 YGCNPGYTLHGSSLLKCM--TGERRAWDYPLPSCIAE-CGGRFKGESSGRILSPGYPFPY 1331
+ CN GY L GS + CM + AW P C A C +G SG I SP +P Y
Sbjct: 367 FTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG-PSGIITSPNFPIQY 425
Query: 1332 DNNLRCMWMI-EVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM--LLKEISGSLIPE 1388
DNN C+W+I ++P ++ L F FD E +D L V DG + D +L ++G+ +P+
Sbjct: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
Query: 1389 GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVF 1448
I ST + + + F TD S GF + +C DPG+P G R G GDT+ F
Sbjct: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKF 545
Query: 1449 QCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR 1508
+C P +EL G++ ITC Q N+ W P C+ C N T SG +LSPN+P Y +
Sbjct: 546 ECQPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
Query: 1509 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSN 1568
C W I + I LAF +EP +DFL I DG + +P++G+F ++LP I SS +
Sbjct: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
Query: 1569 TMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYV 1628
L F++D S GF++ + C DPG +NG R G +LGS++++ CD G++
Sbjct: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
Query: 1629 -LQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYS 1687
QG T+TC++ +G WN A+ C APCG T GT+LSP +P Y +C +
Sbjct: 723 GTQGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWV 781
Query: 1688 IAVPKEFVVFGQFVFFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITI 1746
I + + F F+T + +D +EV DG T + L+ G+ + L +S+ N + +
Sbjct: 782 IEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYL 840
Query: 1747 RFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYIL 1806
F++ + GF Y+ + S C P G+R GN+F VG+ V F C+ GY L
Sbjct: 841 LFSTDKSHSDIGFQLRYETI-TLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
Query: 1807 HGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKIT 1866
+ CE PN QW+ +LP+C CGG + GTILSPG+P+ Y NNLNC W I
Sbjct: 900 SDGEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIE 955
Query: 1867 VPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQ 1926
G G+ +F E D L + G P L +G+ +P + S LY NF
Sbjct: 956 TSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPI---SAGLYGNFT 1011
Query: 1927 ------SDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 1980
SD S+S GF++ ++ L+ C EP+ P+ I+ G ++ VGD ++F C GY L
Sbjct: 1012 AQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRL 1071
Query: 1981 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
+G + ITC+ G R W+ P+P C+A+CG +++ G +LSP FP NY ++ +C ++I
Sbjct: 1072 EGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
Query: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHS 2099
G G+ L+ F D L+V G++ ++ ++G S ++ +L ST+ L F +
Sbjct: 1132 PGKGIQLKARAFELSE-GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
Query: 2100 DYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND-FTVGQTISFECFPGYTLIGNSAL 2158
D +GF + + +++L C DP + G+ + ++ G ++SF C PGY+L G+ L
Sbjct: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
Query: 2159 TCLHGVSRNWNHPLPRCEALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2217
CL G R W+ PLP C A CGG + ++G + SPGYP Y + +C W + G I
Sbjct: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTI 1310
Query: 2218 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS- 2276
++F V TE ++D + +WDGP ++ + + SG + ++ST N ++++F +DF TS
Sbjct: 1311 GLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSK 1370
Query: 2277 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTC-RL 2335
F + + C P N D +E GD +QC PG+ L G+A ++C ++
Sbjct: 1371 QGFAIQFSVSTATSCNDPGIPQNGS--RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
Query: 2336 GERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMF 2395
R +PP C + P +GVILSP YP+ YP + C W ++V Y I +
Sbjct: 1429 ENRFFWQPSPPTC--IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALV 1486
Query: 2396 VEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKG 2455
F E +D L +YDG + SP++ S G I S+ + +FL + +D + G
Sbjct: 1487 FNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG-RIESSSNSLFLAFRSDASVSNAG 1545
Query: 2456 FRIRYI---AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2512
F I Y C P S +G + + +L S V + C G+ + G S+ C G
Sbjct: 1546 FVIDYTENPRESCFDPGSIKNGTRVG-SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
Query: 2513 YHAWDAPVPACQA-------------ISCGIPKAPTNGGI------LTTDYLVGTRVTYF 2553
W+ P P C A +S P+ T+G I + DY+V + +F
Sbjct: 1605 KPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFF 1664
Query: 2554 ---------CNDGYRLSSKELTT-------------------------AVCQSDGTWSNH 2579
+DG+ S+ L++ + + G +
Sbjct: 1665 HTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
Query: 2580 NKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECL----SSGL 2635
PR C +P P G ++G+ S G+ F C+ G+ L GS ECL +
Sbjct: 1725 QAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
Query: 2636 WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLI---GSSVRI----C 2688
W+ S C+ CG G ++ G+ + + N ++++ G+ ++I
Sbjct: 1785 WNVSAPTCVV-PCGGNLTERRGTILSP--GFPEPYLNSLNCVWKIVVPEGAGIQIQVVSF 1841
Query: 2689 QQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2748
+ NW + V G + + S +G ++ + N YL + A
Sbjct: 1842 VTEQNWDS-----LEVFDG-ADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAA 1895
Query: 2749 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2808
+ + +C +P +P+N + + + VV + C PGY L G + + C
Sbjct: 1896 GFHLEY--KTVGLSSCPEPAVPSNGVKTGE----RYLVNDVVSFQCEPGYALQGHAHISC 1949
Query: 2809 QPN--GQWDKPLPECI-------------MIDCGHPGVPPNAVLSGEKYT----FGSTVH 2849
P +W+ P P CI ++ G PG P+ + K FG+ +
Sbjct: 1950 MPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQ 2009
Query: 2850 YSCTGKR------SLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNF 2903
+ + T ++ G +SGS+ S +T S+ F
Sbjct: 2010 FLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 2069
Query: 2904 RTK-STVRYACDTGYILHGSE----ERT-----CLANGSWTGRQPECKAV---QCGNPGT 2950
+ + + Y+ L G + ERT A+ W P C+A +C +P
Sbjct: 2070 KLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVW-DLDPGCEAYELQECPDPEP 2128
Query: 2951 TANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCT--ANGTWSGTLPNCTIISCGDPG 3008
ANG + R G SV + C+ GY L+G V C N W LP C + CG
Sbjct: 2129 FANG-IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNI 2186
Query: 3009 IPANGLRYGDDYVVGQNVSYMC------QPGYTMELNGSRIRTCTING---TWSGVMPTC 3059
+NG Y + + S C G+ + LN S ++T W G T
Sbjct: 2187 TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTA 2246
Query: 3060 RAV-------------------------------------------TCPTPPQISNGRL- 3075
+ CP P + N +
Sbjct: 2247 PRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVV 2306
Query: 3076 -EGTNFDWGFSISYICSPGYELSFPAVLTC 3104
E F+ G + Y C PG+ L +LTC
Sbjct: 2307 TENEEFNIGDIVRYRCLPGFTLVGNEILTC 2336
Score = 263 bits (672), Expect = 2e-69
Identities = 258/955 (27%), Positives = 398/955 (41%), Gaps = 146/955 (15%)
Query: 1986 ITCMPGPVRRWNYPI--PICLAQ-CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIG 2042
I+ PGP RW P Q C + +G + SPGFP YP+ +CTWTI
Sbjct: 4 ISIAPGP--RWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQ 61
Query: 2043 FGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2102
+ L F +F+ E D L V G + + RL+G Q+P+++ S SL SDY+
Sbjct: 62 HRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYA 121
Query: 2103 QNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH 2162
+ QGFH Y+ +C +P NG G+ F +G + + C G+ L G++ LTC
Sbjct: 122 VSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHA 181
Query: 2163 GV--SRNWNHPLPRCEA--LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIY 2218
G S W+ PLP C A CGG + +G I SP +P EY N DC W + G+ I
Sbjct: 182 GSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIA 241
Query: 2219 INFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT---- 2274
+ F Q E YDF+ V G + +S F+G + V S+ N + + F SD
Sbjct: 242 LVFIDFQLEDGYDFLEV-TGTEGSSL---WFTGASLPAPVISSKNWLRLHFTSDGNHRQR 297
Query: 2275 --TSGFFVLSYHAYQLRVCQPPPPVPNAE---ILTE----------------------DD 2307
++ + V + R + P N++ +LT+
Sbjct: 298 GFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGS 357
Query: 2308 EFEIGDIIRYQCLPGFTLVGNAILTCRLGERL--QMDGAPPVCQV-LCPANELRLDSTGV 2364
+F +G +++ C G+ L G+ +TC + PVC+ +C A+ LR +G+
Sbjct: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAH-LR-GPSGI 415
Query: 2365 ILSPGYPDSYPNLQMCAWSI-SVEKGYNITMFVEFFQTEKEFDVLQVYDG--PNIQSPVL 2421
I SP +P Y N C W I ++ I + E F E+ +D L V DG Q VL
Sbjct: 416 ITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVL 475
Query: 2422 ISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESPPHGYIIS 2478
L+G S I S H+++L + D + GF+ Y C P P +G
Sbjct: 476 YILTGT-SVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYG---R 531
Query: 2479 QTGGQLN--SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTN 2536
+ G + + +++ C F LVG+ + C+K+ + W A P C SC +
Sbjct: 532 REGSRFHHGDTLKFECQPAFELVGQKAITCQKN----NQWSAKKPGC-VFSCFFNFTSPS 586
Query: 2537 GGILTTDY----------------LVGTRVTYFCND------GYRLSSKELTTAVCQSDG 2574
G +L+ +Y +R+ ND L K+ TA G
Sbjct: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLG 646
Query: 2575 TWSNHNKTPRCVVIS------------------------------CGELPTPPNGNKIGT 2604
T+S N+ P + S C + P NG + G
Sbjct: 647 TFSG-NQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGD 705
Query: 2605 QTSYGSTAIFTCDLGFM-LVGSAVRECL---SSGLWSESETRCLAGHCGIPELIVNGQVI 2660
GS+ F CD GF+ GS C+ S +W+ + RC A CG +G ++
Sbjct: 706 SLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEA-PCGGHLTSPSGTIL 764
Query: 2661 GENYG--YRDTV----VYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP-GSPI 2713
+ Y+D + V + PG+ + + R + + N+ + V G +P+
Sbjct: 765 SPGWPGFYKDALSCAWVIEAQPGYPIKITFDRF-KTEVNY-----DTLEVRDGRTYSAPL 818
Query: 2714 YGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANS 2773
G +G + + N YL+ K+ Q + + +C DPGIP N
Sbjct: 819 IG--VYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNG 876
Query: 2774 KRESKIEHGN-FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCG 2827
+R HGN F G +V + C+ GY L L C+PN QW + LP C + CG
Sbjct: 877 QR-----HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL-CG 925
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 474 bits (1219), Expect = e-133
Identities = 279/831 (33%), Positives = 389/831 (46%), Gaps = 47/831 (5%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
C+ P G I + S V+++C GF L G S+ +C+ W +P+P C
Sbjct: 2381 CTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDG----TWSSPLPECV 2436
Query: 2525 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2584
+ C P+ NG I + Y C G+ L TT +C +G W P
Sbjct: 2437 PVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGN--TTTLCGENGHWLGGK--PT 2492
Query: 2585 CVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL 2644
C I C + NG T YG T ++C+ GF L G + CL +G W C
Sbjct: 2493 CKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCN 2552
Query: 2645 AGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV 2704
A HC P+ I NG V G +Y Y ++Y C PGF++ G +++ C++ WS +P+C+P+
Sbjct: 2553 AIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEES-GWSSSIPTCMPI 2611
Query: 2705 SCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNC 2764
CG P +F D + GY Q + HPP V
Sbjct: 2612 DCGLPPH----------IDFGDCTKLKDDQGYFEQEDD--MMEVPYVTPHPPYHLGAVAK 2659
Query: 2765 SDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2824
+ N+K NF YGT+V Y CNPGY L G+ VLICQ +G W+ P CI I
Sbjct: 2660 TWE----NTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISI 2715
Query: 2825 DCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDAT 2884
+C P P N L + + GS V YSC L G R C N WSG+ P C
Sbjct: 2716 ECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAI-- 2773
Query: 2885 GTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 2944
+C P +GS + SN+ ST+ Y CD GY+L+G+E RTC + +W +P C V
Sbjct: 2774 -SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVD 2832
Query: 2945 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISC 3004
C +P +ANG+V R D TF + Y+C EG++L G R C ANG+WSG P+C + C
Sbjct: 2833 CSSPPVSANGQV-RGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 2891
Query: 3005 GDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTC 3064
P ANG+ G DY + V++ C GY L+G+ TC +G W +P C+ V C
Sbjct: 2892 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYI--LHGAPKLTCQSDGNWDAEIPLCKPVNC 2949
Query: 3065 PTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD 3124
P +++G G +F G I Y C PGY+L + C+ NG+WSG P CLP C
Sbjct: 2950 GPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 3009
Query: 3125 PGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCE 3184
P I G G F C F L+G S C+ADG WS PHC TSC
Sbjct: 3010 PVI-EYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHC---EHTSCG 3065
Query: 3185 N-PGVPRHGSQNNTFGFQVGS----VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIP 3239
+ P +P N F + S V+ + C+ G+++QGS+ C WS P C P
Sbjct: 3066 SLPMIP------NAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEP 3119
Query: 3240 HSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTW 3290
SC P + A+A G + ++ + C G+ + T+ C+ D W
Sbjct: 3120 LSCGSPPSVANAVATG-EAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRW 3169
Score = 445 bits (1145), Expect = e-124
Identities = 308/1099 (28%), Positives = 460/1099 (41%), Gaps = 140/1099 (12%)
Query: 2282 SYHAYQLRVCQPPP------PVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRL 2335
S+ ++ +C PPP P+P++ + G ++Y C+ GF L GN+ C
Sbjct: 2372 SFPVCKIVLCTPPPLISFGVPIPSSAL-------HFGSTVKYSCVGGFFLRGNSTTLC-- 2422
Query: 2336 GERLQMDGA-----PPVCQVLCPANE------------LRLDSTGVILSPGYPDSYPNLQ 2378
Q DG P V CP E L + PG+
Sbjct: 2423 ----QPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTT 2478
Query: 2379 MCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQSPVLISLSGDYSSAFNI 2434
+C + G +E + ++ +F ++ G + + SA
Sbjct: 2479 LCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTC 2538
Query: 2435 TSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDR 2494
G W D + A +C +P+ +G++ +++ ++C
Sbjct: 2539 LETG-----DWDVDAPSCN--------AIHCDSPQPIENGFV-EGADYSYGAIIIYSCFP 2584
Query: 2495 GFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPK---------------------- 2532
GF++ G + C +S W + +P C I CG+P
Sbjct: 2585 GFQVAGHAMQTCEESG-----WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDD 2639
Query: 2533 ----------APTNGGIL--------------TTDYLVGTRVTYFCNDGYRLSSKELTTA 2568
P + G + ++++L GT V+Y CN GY L +
Sbjct: 2640 MMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVL-- 2697
Query: 2569 VCQSDGTWSNHNKTPRCVVISCGELPTPP-NGNKIGTQTSYGSTAIFTCDLGFMLVGSAV 2627
+CQ DGTW+ P C+ I C +LPT P NG T+TS GS ++C G +L GS +
Sbjct: 2698 ICQEDGTWNG--SAPSCISIEC-DLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDL 2754
Query: 2628 RECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2687
R CL + WS + RC A C P ++NG + G NY Y T+ Y+C+PG+ L G+ R
Sbjct: 2755 RLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRT 2814
Query: 2688 CQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQ 2747
CQ D NW P C+PV C P G+ G+ + F + ++CN G+L++G C
Sbjct: 2815 CQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCL 2874
Query: 2748 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2807
AN WS P C V C+ P AN E +++G + V + C+ GY L G+ L
Sbjct: 2875 ANGSWSGATPDCVPVRCATPPQLANGVTEG-LDYG---FMKEVTFHCHEGYILHGAPKLT 2930
Query: 2808 CQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQ 2867
CQ +G WD +P C ++CG P + +G + G + Y C L G SSR C
Sbjct: 2931 CQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCL 2990
Query: 2868 LNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTC 2927
NG WSGS P C C P +G+ ++F R C G+ L G E TC
Sbjct: 2991 SNGSWSGSSPSC---LPCRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITC 3046
Query: 2928 LANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVI-YSCMEGYILSGPSVRQC 2986
A+G W+ P C+ CG+ N F + +++ +VI YSC GY++ G S C
Sbjct: 3047 EADGQWSSGFPHCEHTSCGSLPMIPN--AFISETSSWKENVITYSCRSGYVIQGSSDLIC 3104
Query: 2987 TANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTC 3046
T G WS P C +SCG P AN + G+ + V C GYTM+ + TC
Sbjct: 3105 TEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTF-TC 3163
Query: 3047 TINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVG 3106
+G W +C CP P I++ + G +F +S C+ GY + C
Sbjct: 3164 QKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 3223
Query: 3107 NGTWSGEV--PQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQA 3164
+GTW C P CG P P G G + ++S + + C + L G+ R+CQ
Sbjct: 3224 DGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQE 3283
Query: 3165 DGTWSGSSPHCIEPTQTSCENPGVPRHGS---QNNTFGFQVGSVVQFHCKKGHLLQGSTT 3221
+ WSG C E T CE P +G +N T G V + C +G+ L+G +
Sbjct: 3284 NRQWSGGVAICKE---TRCETPLEFLNGKADIENRT----TGPNVVYSCNRGYSLEGPSE 3336
Query: 3222 RTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEH 3281
C + TWS P C P+ C P ++ + C+ GF L G H
Sbjct: 3337 AHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQG---H 3393
Query: 3282 RV--CRSDNTWTGKVPICE 3298
+ C D TWT CE
Sbjct: 3394 GIITCNPDETWTQTSAKCE 3412
Score = 444 bits (1141), Expect = e-124
Identities = 265/822 (32%), Positives = 384/822 (46%), Gaps = 38/822 (4%)
Query: 2486 SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYL 2545
++V + C+ G+ L+G +C++ W+ P+C +I C +P AP NG + T+
Sbjct: 2679 TMVSYTCNPGYELLGNPVLICQEDG----TWNGSAPSCISIECDLPTAPENGFLRFTETS 2734
Query: 2546 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQ 2605
+G+ V Y C G+ L+ +L +C + WS +PRC ISC + NG+ G+
Sbjct: 2735 MGSAVQYSCKPGHILAGSDLR--LCLENRKWSG--ASPRCEAISCKKPNPVMNGSIKGSN 2790
Query: 2606 TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYG 2665
+Y ST + CD G++L G+ R C W E E C+ C P + NGQV G+ Y
Sbjct: 2791 YTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYT 2850
Query: 2666 YRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFN 2725
++ + Y CN GF L G+ R+C + +WSG P CVPV C P G T G + F
Sbjct: 2851 FQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFM 2910
Query: 2726 DVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHG--- 2782
VTF C+ GY++ G K CQ++ W P+CK VNC P + HG
Sbjct: 2911 KEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP---------EDLAHGFPN 2961
Query: 2783 --NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGE 2840
+F +G + Y C PGY L G+S C NG W P C+ C P + V +G
Sbjct: 2962 GFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTV-NGT 3020
Query: 2841 KYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQE 2900
+ G C LLG S TC+ +G WS PHC + G+ P P +
Sbjct: 3021 DFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSL--PMIPNAFISET 3078
Query: 2901 SNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRID 2960
S+++ ++ + Y+C +GY++ GS + C G W+ P C+ + CG+P + AN V +
Sbjct: 3079 SSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANA-VATGE 3136
Query: 2961 GTTFSSSVIYSCMEGYIL-SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD 3019
T+ S V C+EGY + + C +G W +C+ C P + L +GDD
Sbjct: 3137 AHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDD 3196
Query: 3020 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP--TCRAVTCPTPPQISNGRLEG 3077
+ V + VS C GYT E G I C ++GTW +C V+C P +G + G
Sbjct: 3197 FSVNRQVSVSCAEGYTFE--GVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVG 3254
Query: 3078 TNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS 3137
+ + + +I Y C PGYEL C N WSG V C C P GK + ++
Sbjct: 3255 SKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIEN 3314
Query: 3138 FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNT 3197
V +SCN + L G S C +GTWS P C C P V + +
Sbjct: 3315 RTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLC---KPNPCPVPFVIPENALLSE 3371
Query: 3198 FGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMD 3257
F V V C++G LLQG TC PD TW+ +C SC P +A G+
Sbjct: 3372 KEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVH 3431
Query: 3258 LPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3299
+G + Y+C G+ L G VC + TWT PIC A
Sbjct: 3432 Y-QYGDMITYSCYSGYMLEGFL-RSVCLENGTWTSP-PICRA 3470
Score = 416 bits (1069), Expect = e-115
Identities = 257/865 (29%), Positives = 376/865 (43%), Gaps = 72/865 (8%)
Query: 2486 SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYL 2545
S V CD GF+LVG C W P+P C+ ISCG+P NG D+
Sbjct: 1652 SKVNLFCDPGFQLVGNPVQYCLNQGQ----WTQPLPHCERISCGVPPPLENGFHSADDFY 1707
Query: 2546 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT----PRCVV-------------- 2587
G+ VTY CN+GY L + C +G+W+ + + C V
Sbjct: 1708 AGSTVTYQCNNGYYLLGD--SRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVD 1765
Query: 2588 ---------------------ISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSA 2626
I C P NG+ G + G+ F+C G+ L+G
Sbjct: 1766 GSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVT 1825
Query: 2627 VRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVR 2686
CL SG W+ C A CG P + NG + + + V Y+CN G+ L G
Sbjct: 1826 KITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKES 1885
Query: 2687 ICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC 2746
C + +WS P C PV C P + G+ +G + ++SC+ GY +QGP+ +C
Sbjct: 1886 SCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC 1945
Query: 2747 QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL 2806
A+ W PP C +V C +P PA +++ I NFT+ V Y C GY L G +
Sbjct: 1946 TASGIWDRAPPACHLVFCGEP--PA--IKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTI 2001
Query: 2807 ICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTC 2866
C +G+W + +C+ + C P + +A FG Y C+ SL S C
Sbjct: 2002 ECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLC 2061
Query: 2867 QLNGHW----SGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYIL 2919
G W P C C P + + S ++ F S V + C G++L
Sbjct: 2062 NAQGKWVPPEGQDMPRC---IAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVL 2118
Query: 2920 HGSEERTCLANGSW--TGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYI 2977
+ S + C+ G W + +C V+CG P + NG +F + V YSC +G+
Sbjct: 2119 NTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-SNYSFGAMVAYSCNKGFY 2177
Query: 2978 LSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG-LRYGDDYVVGQNVSYMCQPGYTM 3036
+ G C A G WS +P C +SCG+P NG L + + V Y C PGY
Sbjct: 2178 IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGY-- 2235
Query: 3037 ELNGSRIRTCTINGTWSGVMP-TCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYE 3095
+ GS + C N W P C + C PP I NG ++G NF+ G + + C+ GYE
Sbjct: 2236 KSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYE 2295
Query: 3096 LSFPAVLTCVGNGTWSGEV-PQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFIL 3154
L + TC +G W+ + P+C+P C +P + + V+FSC +L
Sbjct: 2296 LVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVL 2355
Query: 3155 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGH 3214
G S C W+ S P C C P + G + GS V++ C G
Sbjct: 2356 QGPSVLKCLPSQQWNDSFPVC---KIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGF 2412
Query: 3215 LLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFF 3274
L+G++T C PD TWS PEC+P C QPE + ++ + ++ T +YTC+PGF
Sbjct: 2413 FLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPN-GIIDVQGLAYLSTALYTCKPGFE 2471
Query: 3275 LAGGTEHRVCRSDNTWTGKVPICEA 3299
L G T +C + W G P C+A
Sbjct: 2472 LVGNTT-TLCGENGHWLGGKPTCKA 2495
Score = 415 bits (1067), Expect = e-115
Identities = 501/2108 (23%), Positives = 767/2108 (36%), Gaps = 337/2108 (15%)
Query: 1235 DEGFQLVYTSFE-----------LSHCE--DPGIP---QFGYKISDQGHFAGSTIIYGCN 1278
D GFQLV + L HCE G+P + G+ +D +AGST+ Y CN
Sbjct: 1659 DPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADD-FYAGSTVTYQCN 1717
Query: 1279 PGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGGRFKGESSGRILSPGYPFPYDNNLR 1336
GY L G S + C + +W+ PSC + EC G S
Sbjct: 1718 NGYYLLGDSRMFCT--DNGSWNGVSPSCLDVDECA---VGSDCSEHAS------------ 1760
Query: 1337 CMWMIEVDPGNIVSL--QFLAFDTEASHDILRVWDGPPENDMLLKEIS--GSLIPEGIHS 1392
+ VD I S + + I G PEN EI G+ +
Sbjct: 1761 ---CLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQE 1817
Query: 1393 TLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP 1452
++ + T + I + +V+ C P +P NG G V ++C+
Sbjct: 1818 GYQLMGVTKITCLESGEWNHLIPYCKAVS--CGKPAIPENGCIEELAFTFGSKVTYRCNK 1875
Query: 1453 GYELQGEERITCIQVENRYFWQPSPPVCI-APCGGNLTGSSGFILSPNFPHPYPHSRDCD 1511
GY L G++ +C+ + W SPPVC C ++G + + S CD
Sbjct: 1876 GYTLAGDKESSCLANSS---WSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCD 1932
Query: 1512 WTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMH 1571
++ +I I+D L+ + + + + + +N
Sbjct: 1933 TGYSLQGPSIIECTASG-----------IWDRAPPACHLVFCGEPPAIKDAVITGNN--- 1978
Query: 1572 LAFRSDGSVSYT---GFHL----------------EYKAKLRESCFDPGNIMNGTRLGMD 1612
F +V+YT G+ L + L SC +P + + +
Sbjct: 1979 --FTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAH 2036
Query: 1613 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSP 1672
G YYC GY L S L C P + +P C A + ++L
Sbjct: 2037 RLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILES 2096
Query: 1673 NYPKNYSVG--------HNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLL 1724
++ G V + + E + GQ+ S+ + P +
Sbjct: 2097 VSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGY 2156
Query: 1725 SSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFG- 1783
+S S G + S I+ A G +P C P+ G
Sbjct: 2157 ASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWS--SPIPTCHPVSCGEPPKVENGF 2214
Query: 1784 --RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1841
G F S V + CNPGY GS C+ + W+ P VP
Sbjct: 2215 LEHTTGRIFE--SEVRYQCNPGYKSVGSPVFVCQ----ANRHWHSESPLMCVP------- 2261
Query: 1842 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQV-QVVSFATEHNWDSLDFYDGGDNN-- 1898
L G P P N +G +V V F ++ + GD++
Sbjct: 2262 -----LDCGKPPPIQNGFM--------KGENFEVGSKVQFFCNEGYELV-----GDSSWT 2303
Query: 1899 APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGI 1958
+ G ++ + P + + CPEP + +
Sbjct: 2304 CQKSGKWNKKSNPKCMPA------------------------------KCPEPPLLENQL 2333
Query: 1959 KIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMSDFSGV 2017
+ + VV+F C +G+ LQG S + C+P ++WN P+C + C
Sbjct: 2334 VLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPS--QQWNDSFPVCKIVLCTPPP------ 2385
Query: 2018 ILSPGFPGNYPSS---LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVI 2074
++S G P PSS T + GF F+ ++ T+ S +
Sbjct: 2386 LISFGVP--IPSSALHFGSTVKYSCVGGF-----FLRGNSTTLCQPDGTWSSPLPECVPV 2438
Query: 2075 GRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS--------------- 2119
+IP+ + + Y + K GF +V L
Sbjct: 2439 ECPQPEEIPNGIIDV--QGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2496
Query: 2120 -CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2178
C P+ NG D GQT+++ C G+ L G SALTCL + +W+ P C A+
Sbjct: 2497 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLE--TGDWDVDAPSCNAI 2554
Query: 2179 -CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWD 2237
C NG + Y CF PG
Sbjct: 2555 HCDSPQPIENGFVEGADYSYGAIIIYSCF------PGF---------------------- 2586
Query: 2238 GPDQNSPQIGQFSGNTALESVYSTSNQILIKF------HSDF-------TTSGFFVLSYH 2284
Q+ + T ES +S+S + H DF G+F
Sbjct: 2587 -------QVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDD 2639
Query: 2285 AYQLRVCQPPPPVPNAEIL-----------TEDDEFEIGDIIRYQCLPGFTLVGNAILTC 2333
++ P PP + T F G ++ Y C PG+ L+GN +L C
Sbjct: 2640 MMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLIC 2699
Query: 2334 RLGERLQMDGAPPVC-QVLC-----PANE-LRLDSTGV------ILSPGYPDSYPNLQMC 2380
+ E +G+ P C + C P N LR T + PG+ + +L++C
Sbjct: 2700 Q--EDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLC 2757
Query: 2381 AWSISVEKGYNITMFVEFFQTEKEFDVLQ-VYDGPNIQSPVLISLSGDYSSAFNITSNGH 2439
+ K + E +K V+ G N + D N T
Sbjct: 2758 ---LENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTER-- 2812
Query: 2440 EVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLV 2499
+ D N + I I CS+P +G + + + C+ GF L
Sbjct: 2813 ----RTCQDDKNWDEDEPI-CIPVDCSSPPVSANGQVRGDEY-TFQKEIEYTCNEGFLLE 2866
Query: 2500 GKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYR 2559
G S VC + +W P C + C P NG DY VT+ C++GY
Sbjct: 2867 GARSRVCLANG----SWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYI 2922
Query: 2560 LSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLG 2619
L T CQSDG W + P C ++CG +G G +G + C G
Sbjct: 2923 LHGAPKLT--CQSDGNWDA--EIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPG 2978
Query: 2620 FMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFR 2679
+ L G++ R CLS+G WS S CL C P +I G V G ++ QC GF+
Sbjct: 2979 YKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFK 3037
Query: 2680 LIGSSVRICQQDHNWSGQLPSCVPVSCGH-PGSPIYGRTSGNGFNFNDVVTFSCNIGYLM 2738
L+G S C+ D WS P C SCG P P + + + N V+T+SC GY++
Sbjct: 3038 LLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKEN-VITYSCRSGYVI 3096
Query: 2739 QGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGY 2798
QG + C WS P P+C+ ++C P AN+ + TY + V C GY
Sbjct: 3097 QGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAH----TYESEVKLRCLEGY 3152
Query: 2799 FL-FGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRS 2857
+ + CQ +G+W C C P + ++ G+ ++ V SC +
Sbjct: 3153 TMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYT 3212
Query: 2858 LLGQSSRTCQLNGHWSGSQPHCSGDATG--TCGDPGTPGHGSRQESNFRTKSTVRYACDT 2915
G + CQL+G W +P S ++ +CG P +P HG S + +ST+ Y C+
Sbjct: 3213 FEGVNISVCQLDGTW---EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEP 3269
Query: 2916 GYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEG 2975
GY L G+ ER C N W+G CK +C P NGK I+ T +V+YSC G
Sbjct: 3270 GYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKA-DIENRTTGPNVVYSCNRG 3328
Query: 2976 YILSGPSVRQCTANGTWSGTLPNCTIISCGDPG-IPANGLRYGDDYVVGQNVSYMCQPGY 3034
Y L GPS CT NGTWS +P C C P IP N L ++ V QNVS C+ G+
Sbjct: 3329 YSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGF 3388
Query: 3035 TMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGY 3094
++ +G I TC + TW+ C ++C P + N G ++ +G I+Y C GY
Sbjct: 3389 LLQGHG--IITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGY 3446
Query: 3095 ELSFPAVLTCVGNGTW-SGEVPQCLPKF-CGDPGIPAQGKREGKSFIYQSEVSFSCNFPF 3152
L C+ NGTW S + + + +F C + GI +R + + C P
Sbjct: 3447 MLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGI---CQRPNACSCPEGWMGRLCEEPI 3503
Query: 3153 ILVGS-------STRICQADGTWSGSSPH-------------CIEPTQTSCENPGVPRHG 3192
++ + C W+GS H C+ P + C + +
Sbjct: 3504 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Query: 3193 SQNNTFGF 3200
S+ GF
Sbjct: 3564 SRKRRTGF 3571
Score = 412 bits (1060), Expect = e-114
Identities = 261/849 (30%), Positives = 392/849 (46%), Gaps = 45/849 (5%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSV---VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVP 2521
C P +P +G+ + G++ +V V ++C G++L+G + C +S W+ +P
Sbjct: 1789 CKAPGNPENGH----SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESG----EWNHLIP 1840
Query: 2522 ACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
C+A+SCG P P NG I + G++VTY CN GY L+ + ++ C ++ +WS +
Sbjct: 1841 YCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESS--CLANSSWS--HS 1896
Query: 2582 TPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESET 2641
P C + C NG I + +Y STA ++CD G+ L G ++ EC +SG+W +
Sbjct: 1897 PPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPP 1956
Query: 2642 RCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2701
C CG P I + + G N+ +R+TV Y C G+ L G C D WS C
Sbjct: 1957 ACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2016
Query: 2702 VPVSCGHPGSPIYGRTSGNGFN--FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP--- 2756
+ VSC P PI S + F D+ + C+ GY + ++ C A +W P
Sbjct: 2017 LAVSCDEP--PIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD 2074
Query: 2757 -PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWD 2815
P C C P + S ES + F G+VV + C G+ L S+ + C GQW+
Sbjct: 2075 MPRCIAHFCEKPPSVSYSILES-VSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWN 2133
Query: 2816 KPLP---ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 2872
P P +CI + CG P N SG Y+FG+ V YSC + G+ TC+ G W
Sbjct: 2134 -PSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQW 2192
Query: 2873 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT-KSTVRYACDTGYILHGSEERTCLANG 2931
S P C +CG+P +G + + R +S VRY C+ GY GS C AN
Sbjct: 2193 SSPIPTCH---PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANR 2249
Query: 2932 SWTGRQP-ECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANG 2990
W P C + CG P NG + + S V + C EGY L G S C +G
Sbjct: 2250 HWHSESPLMCVPLDCGKPPPIQNG-FMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSG 2308
Query: 2991 TWS-GTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN 3049
W+ + P C C +P + N L + V++ C+ G+ L G + C +
Sbjct: 2309 KWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHV--LQGPSVLKCLPS 2366
Query: 3050 GTWSGVMPTCRAVTCPTPPQISNG-RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNG 3108
W+ P C+ V C PP IS G + + +G ++ Y C G+ L + C +G
Sbjct: 2367 QQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDG 2426
Query: 3109 TWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTW 3168
TWS +P+C+P C P G + + Y S ++C F LVG++T +C +G W
Sbjct: 2427 TWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHW 2486
Query: 3169 SGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL 3228
G P C C P +G + T G V + C +G L+G + TCL
Sbjct: 2487 LGGKPTC---KAIECLKPKEILNGKFSYT-DLHYGQTVTYSCNRGFRLEGPSALTCLETG 2542
Query: 3229 TWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN 3288
W P C C P+ + V G D S+G +IY+C PGF +AG + C ++
Sbjct: 2543 DWDVDAPSCNAIHCDSPQPIENGFVEGADY-SYGAIIIYSCFPGFQVAGHA-MQTC-EES 2599
Query: 3289 TWTGKVPIC 3297
W+ +P C
Sbjct: 2600 GWSSSIPTC 2608
Score = 391 bits (1005), Expect = e-108
Identities = 264/887 (29%), Positives = 373/887 (42%), Gaps = 75/887 (8%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC- 2523
C P +G+ S S V + C+ G+ L+G S C + +W+ P+C
Sbjct: 1690 CGVPPPLENGFH-SADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNG----SWNGVSPSCL 1744
Query: 2524 ----------------------------------------QAISCGIPKAPTNGGILTTD 2543
+ I C P P NG
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEI 1804
Query: 2544 YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIG 2603
Y VG VT+ C +GY+L +T C G W NH P C +SCG+ P NG
Sbjct: 1805 YTVGAEVTFSCQEGYQLMG--VTKITCLESGEW-NH-LIPYCKAVSCGKPAIPENGCIEE 1860
Query: 2604 TQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN 2663
++GS + C+ G+ L G CL++ WS S C C PE I NG+ I
Sbjct: 1861 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSG 1920
Query: 2664 YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFN 2723
Y T Y C+ G+ L G S+ C W P+C V CG P + +GN F
Sbjct: 1921 LTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFT 1980
Query: 2724 FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGN 2783
F + VT++C GY + G +C A+ +WS C V+C +P I ++ E+ +
Sbjct: 1981 FRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPET----AH 2036
Query: 2784 FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKP----LPECIMIDCGHPGVPPNAVL-- 2837
+G + FY C+ GY L +S L+C G+W P +P CI C P ++L
Sbjct: 2037 RLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILES 2096
Query: 2838 -SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG 2896
S K+ GS V + C L + C G W+ S P CG+P + +G
Sbjct: 2097 VSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-PMSIQCIPVRCGEPPSIMNG 2155
Query: 2897 SRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKV 2956
SN+ + V Y+C+ G+ + G ++ TC A G W+ P C V CG P NG +
Sbjct: 2156 YASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFL 2215
Query: 2957 FRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLP-NCTIISCGDPGIPANGLR 3015
G F S V Y C GY G V C AN W P C + CG P NG
Sbjct: 2216 EHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFM 2275
Query: 3016 YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVM-PTCRAVTCPTPPQISNGR 3074
G+++ VG V + C GY EL G TC +G W+ P C CP PP + N
Sbjct: 2276 KGENFEVGSKVQFFCNEGY--ELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQL 2333
Query: 3075 -LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKR 3133
L+ + G +++ C G+ L P+VL C+ + W+ P C C P + + G
Sbjct: 2334 VLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVP 2392
Query: 3134 EGKSFI-YQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG 3192
S + + S V +SC F L G+ST +CQ DGTWS P C+ C P +G
Sbjct: 2393 IPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECV---PVECPQPEEIPNG 2449
Query: 3193 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN 3252
+ G S + CK G L G+TT C + W G +P C C +P+ +
Sbjct: 2450 I-IDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGK 2508
Query: 3253 VVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3299
DL +G T+ Y+C GF L G + C W P C A
Sbjct: 2509 FSYTDL-HYGQTVTYSCNRGFRLEGPSA-LTCLETGDWDVDAPSCNA 2553
Score = 360 bits (925), Expect = 1e-98
Identities = 240/766 (31%), Positives = 330/766 (43%), Gaps = 79/766 (10%)
Query: 2609 GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRD 2668
GS CD GF LVG+ V+ CL+ G W++ C CG+P + NG +++
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGS 1710
Query: 2669 TVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCV-------------------------- 2702
TV YQCN G+ L+G S C + +W+G PSC+
Sbjct: 1711 TVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYIC 1770
Query: 2703 ---------------PVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQ 2747
P+ C PG+P G +SG + VTFSC GY + G TK C
Sbjct: 1771 SCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCL 1830
Query: 2748 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2807
+ +W+H P CK V+C P IP N IE FT+G+ V Y CN GY L G
Sbjct: 1831 ESGEWNHLIPYCKAVSCGKPAIPEN----GCIEELAFTFGSKVTYRCNKGYTLAGDKESS 1886
Query: 2808 CQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRT 2865
C N W P C + C P N +LSG T+ ST YSC SL G S
Sbjct: 1887 CLANSSWSHSPPVCEPVKCSSPENINNGKYILSG--LTYLSTASYSCDTGYSLQGPSIIE 1944
Query: 2866 CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEER 2925
C +G W + P C CG+P +NF ++TV Y C GY L G +
Sbjct: 1945 CTASGIWDRAPPACH---LVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTI 2001
Query: 2926 TCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQ 2985
CLA+G W+ +C AV C P + F Y C +GY L+ S
Sbjct: 2002 ECLADGKWSRSDQQCLAVSCDEPPIVDHASP-ETAHRLFGDIAFYYCSDGYSLADNSQLL 2060
Query: 2986 CTANGTW----SGTLPNCTIISCGDPGIPANGLRYG---DDYVVGQNVSYMCQPGYTMEL 3038
C A G W +P C C P + + + G VS+ C G+ L
Sbjct: 2061 CNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFV--L 2118
Query: 3039 NGSRIRTCTINGTW--SGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYEL 3096
N S C G W S + C V C PP I NG G+N+ +G ++Y C+ G+ +
Sbjct: 2119 NTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYI 2178
Query: 3097 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILV 3155
TC G WS +P C P CG+P G E + I++SEV + CN + V
Sbjct: 2179 KGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSV 2238
Query: 3156 GSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHL 3215
GS +CQA+ W SP P C P ++G F+VGS VQF C +G+
Sbjct: 2239 GSPVFVCQANRHWHSESPLMCVP--LDCGKPPPIQNGFMKGE-NFEVGSKVQFFCNEGYE 2295
Query: 3216 LQGSTTRTCLPDLTWS-GIQPECIPHSCKQPETPAHAN-VVGMDLPSHGYTLIYTCQPGF 3273
L G ++ TC W+ P+C+P C PE P N +V +L + + ++C+ G
Sbjct: 2296 LVGDSSWTCQKSGKWNKKSNPKCMPAKC--PEPPLLENQLVLKELTTEVGVVTFSCKEGH 2353
Query: 3274 FLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP--ALGTPSP 3317
L G + + C W P+C KI++ P P + G P P
Sbjct: 2354 VLQGPSVLK-CLPSQQWNDSFPVC----KIVLCTPPPLISFGVPIP 2394
Score = 303 bits (777), Expect = 2e-81
Identities = 236/868 (27%), Positives = 348/868 (40%), Gaps = 128/868 (14%)
Query: 2511 YGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDG------------- 2557
YGY D +P+ A++C ++ D GT ++Y ++G
Sbjct: 1436 YGYVMLDGMLPSLHALTCTFWMKSSD------DMNYGTPISYAVDNGSDNTLLLTDYNGW 1489
Query: 2558 --YRLSSKELTTAVCQSDG-------TWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSY 2608
Y +++T +DG TW++ N + + G+L G +G
Sbjct: 1490 VLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYID--GKLSDGGAGLSVGLPIPG 1547
Query: 2609 GSTAIFTCDL-----GFMLVGSAVRECLSSGLW----SESETRCLAGHCGIPELIVNGQV 2659
G + + GF S V LW S + + LA C PE + G V
Sbjct: 1548 GGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSC--PEELSKGNV 1605
Query: 2660 IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG 2719
+ V G I S C G +P RT+
Sbjct: 1606 LAWPDFLSGIV------GKVKIDSKSIFCSDCPRLGGSVPHL--------------RTAS 1645
Query: 2720 NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKI 2779
V C+ G+ + G C QW+ P P C+ ++C P N +
Sbjct: 1646 EDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSA-- 1703
Query: 2780 EHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMID-------------- 2825
+F G+ V Y CN GY+L G S + C NG W+ P C+ +D
Sbjct: 1704 --DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC 1761
Query: 2826 ---------------------------CGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSL 2858
C PG P N SGE YT G+ V +SC L
Sbjct: 1762 LNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQL 1821
Query: 2859 LGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYI 2918
+G + TC +G W+ P+C +CG P P +G +E F S V Y C+ GY
Sbjct: 1822 MGVTKITCLESGEWNHLIPYCK---AVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYT 1878
Query: 2919 LHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYIL 2978
L G +E +CLAN SW+ P C+ V+C +P NGK + + G T+ S+ YSC GY L
Sbjct: 1879 LAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK-YILSGLTYLSTASYSCDTGYSL 1937
Query: 2979 SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMEL 3038
GPS+ +CTA+G W P C ++ CG+P + + G+++ V+Y C+ GYT L
Sbjct: 1938 QGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYT--L 1995
Query: 3039 NGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSF 3098
G C +G WS C AV+C PP + + E + +G Y CS GY L+
Sbjct: 1996 AGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLAD 2055
Query: 3099 PAVLTCVGNGTW----SGEVPQCLPKFCGDPGIPAQGKREGKS---FIYQSEVSFSCNFP 3151
+ L C G W ++P+C+ FC P + E S F S VSF C
Sbjct: 2056 NSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEG 2115
Query: 3152 FILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCK 3211
F+L S+ C G W+ SP I+ C P +G + + + G++V + C
Sbjct: 2116 FVLNTSAKIECMRGGQWN-PSPMSIQCIPVRCGEPPSIMNGYASGS-NYSFGAMVAYSCN 2173
Query: 3212 KGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQP---ETPAHANVVGMDLPSHGYTLIYT 3268
KG ++G TC WS P C P SC +P E + G S + Y
Sbjct: 2174 KGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESE---VRYQ 2230
Query: 3269 CQPGFFLAGGTEHRVCRSDNTWTGKVPI 3296
C PG+ G VC+++ W + P+
Sbjct: 2231 CNPGYKSVGSPVF-VCQANRHWHSESPL 2257
Score = 107 bits (268), Expect = 2e-22
Identities = 296/1393 (21%), Positives = 465/1393 (33%), Gaps = 236/1393 (16%)
Query: 893 KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 952
KI +S+ + L +P H R D GS V+ CD G++L C W
Sbjct: 1620 KIDSKSIFCSDCPRLGGSVP-HLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQW 1678
Query: 953 SHPLPTCDAL-CGGDVRGPSGTILSPGY---PEFYPNSLNCTWTVDVTHGKGVQFNFHTF 1008
+ PLP C+ + CG V P L G+ +FY S VT+ Q N +
Sbjct: 1679 TQPLPHCERISCG--VPPP----LENGFHSADDFYAGS-------TVTY----QCNNGYY 1721
Query: 1009 HLEDHHDYLLITENGSFTQPLAR-------LTGSDLPPTINAGLYGNFRAQLRFISDFSI 1061
L D + T+NGS+ GSD + +I
Sbjct: 1722 LLGDSR--MFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC-----LNVDGSYICSCVP 1774
Query: 1062 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1121
Y G +E C+ PG P+ G G + +G +TFSC GY+L G ++I CL
Sbjct: 1775 PYTGDGKNCAE--PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES 1832
Query: 1122 GRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISAR 1180
G W+ +P C A CG A G + + + + C + K + A
Sbjct: 1833 GE--WNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN 1890
Query: 1181 TFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQ-----LWLEFNSDTEGTD 1235
+ V + G + + GLT ST++ L+ S E T
Sbjct: 1891 SSWSHSPPVCEPVKCSSPENINNGKYI---LSGLTYLSTASYSCDTGYSLQGPSIIECTA 1947
Query: 1236 EG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMT 1293
G + + L C +P P + +F +T+ Y C GYTL G ++C+
Sbjct: 1948 SGIWDRAPPACHLVFCGEP--PAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLA 2005
Query: 1294 GERRAWDYPLPSCIA--------------ECGGRFKGESSGRILSPGYPFPYDNNLRCMW 1339
+ W C+A E R G+ + S GY ++ L C
Sbjct: 2006 DGK--WSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNA 2063
Query: 1340 MIEVDPGNIVSL-----QFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIP----EGI 1390
+ P + F S+ IL E+ K +GS++ EG
Sbjct: 2064 QGKWVPPEGQDMPRCIAHFCEKPPSVSYSIL-------ESVSKAKFAAGSVVSFKCMEGF 2116
Query: 1391 HSTLNI-VTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQ 1449
LN I+ + S +IQ + C +P MNG +G G V +
Sbjct: 2117 --VLNTSAKIECMRGGQWNPSPMSIQ---CIPVRCGEPPSIMNGYASGSNYSFGAMVAYS 2171
Query: 1450 CDPGYELQGEERITCIQVENRYFWQPSPPVC-IAPCGGNLTGSSGFILSPNFPHPYPHSR 1508
C+ G+ ++GE++ TC E W P C CG +GF+ H
Sbjct: 2172 CNKGFYIKGEKKSTC---EATGQWSSPIPTCHPVSCGEPPKVENGFL-----EHTTGRIF 2223
Query: 1509 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLP-------- 1560
+ + N Y S+ F + N + S SPL+ D P
Sbjct: 2224 ESEVRYQCNPGYK-SVGSPVFVCQANRHW-------HSESPLMCVPLDCGKPPPIQNGFM 2275
Query: 1561 --ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK---------LRESCFDPGNIMNGTRL 1609
E E S V + + + K + C +P + N L
Sbjct: 2276 KGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVL 2335
Query: 1610 GMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1669
VT+ C G+VLQG S L C+ WN + P C +
Sbjct: 2336 KELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQ----WNDSFPVC-------------KI 2378
Query: 1670 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV-------FFQTSLHDVVEVYDGPTQQSS 1722
+ P S G + +P + FG V FF + DG T S
Sbjct: 2379 VLCTPPPLISFG------VPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDG-TWSSP 2431
Query: 1723 LLSSLS-GSHSGESLPLSSGNQITIRFTSVGPITAK-GFHFVYQAV-------------P 1767
L + E +P + + + S T K GF V P
Sbjct: 2432 LPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKP 2491
Query: 1768 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRC-ETVPNSLAQWND 1826
+ +C E G+ + G +V + CN G+ L G A+ C ET W+
Sbjct: 2492 TCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLET-----GDWDV 2546
Query: 1827 SLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1885
P+C + C + G+ E D + + + G + + E
Sbjct: 2547 DAPSCNAIHCD------SPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG 2600
Query: 1886 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNL-----YLNFQSDIS-----VSAAG 1935
W S + P PH+ L Y + D+
Sbjct: 2601 WSS---------SIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPP 2651
Query: 1936 FHLEYTAIGLDSCPE-PQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVR 1994
+HL A ++ E P T SS ++ G +VS+ C+ GY L G+ + C
Sbjct: 2652 YHLGAVAKTWENTKESPATHSS------NFLYGTMVSYTCNPGYELLGNPVLICQEDGT- 2704
Query: 1995 RWNYPIPICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS 2053
WN P C++ +C + +G + C ++ G + L N
Sbjct: 2705 -WNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCK-PGHILAGSDLRLCLENRK 2762
Query: 2054 TETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD-----------YS 2102
E S + G + G + T+ ++LY+ D
Sbjct: 2763 WSGASPRCEAISCKKPNPVMNGSIKGS-------NYTYLSTLYYECDPGYVLNGTERRTC 2815
Query: 2103 QNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH 2162
Q+ + + C P NG V G+++T + I + C G+ L G + CL
Sbjct: 2816 QDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCL- 2874
Query: 2163 GVSRNWNHPLPRC 2175
+ +W+ P C
Sbjct: 2875 -ANGSWSGATPDC 2886
Score = 107 bits (268), Expect = 2e-22
Identities = 289/1400 (20%), Positives = 477/1400 (34%), Gaps = 318/1400 (22%)
Query: 193 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII 252
+F G + + C+ G++L+ ++ C+ S P+ I CG
Sbjct: 2101 KFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS---PMSIQCIPVRCG---------- 2147
Query: 253 SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG---SEPPTIWLSG 309
PS N Y + ++ ++ + S + EK E G S PT
Sbjct: 2148 EPPSIMNGYASGSNYSFGAMV----AYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVS 2203
Query: 310 MNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSI 369
PP + + F+ + R YQ +KS G +F + N + S
Sbjct: 2204 CGEPPKVENG-------FLEHTTGRIFESEVRYQCNPG--YKSVGSPVFVCQANRHWHS- 2253
Query: 370 LNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVF 429
E + C P +NG G +F +GS VQF C+E Y L G S TCQ+ +
Sbjct: 2254 --ESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGK-- 2309
Query: 430 AAWS-DHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFE 488
W+ P C C P P + Q+ +
Sbjct: 2310 --WNKKSNPKCMPAKC-------------PEPPLLEN------------------QLVLK 2336
Query: 489 EFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGF 548
E E+G T + +G VL G P ++ + SQ W
Sbjct: 2337 ELTTEVGVVTFSCKEG----------HVLQG---PSVLKCLPSQQW-------------- 2369
Query: 549 KVNYKEIEKESCGDPGTPLYGIR-EGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWS 607
++ + C P +G+ +++ C GF L G + +CQ + WS
Sbjct: 2370 NDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWS 2429
Query: 608 ANIPICI-FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES 666
+ +P C+ C P G + +G ++T PG F+L
Sbjct: 2430 SPLPECVPVECPQPEEIPNGII----DVQGLAYLSTALYT--CKPG---------FELVG 2474
Query: 667 QFDFLAVKDGD--------------SPESPILGTFTGAEVPSHLT---SNSHILRLEFQA 709
L ++G P+ + G F+ ++ T S + RLE +
Sbjct: 2475 NTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPS 2534
Query: 710 DHSMSGRG-FNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTET 768
+ G +++ + C P N G ++ G+ I C GF + G
Sbjct: 2535 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGF-QVAGHAM 2593
Query: 769 ITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
TC + WS IP C ++C + G
Sbjct: 2594 QTC----EESGWSSSIPTC-------------------------MPIDCGLPPHIDFGDC 2624
Query: 829 IKITFERFQTELNYDVLEV----HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 884
K+ ++ E D++EV P L + ++ T+ S SNF+Y T
Sbjct: 2625 TKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHS-SNFLY--GTMV 2681
Query: 885 NSRSNNGFKIHYESVTV---------NTYSCLD-----PGIPVHGRRYGHDFSIGSTVSF 930
+ N G+++ V + + SC+ P P +G + S+GS V +
Sbjct: 2682 SYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQY 2741
Query: 931 SCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--------CGGDVRGPSGTILSPGYPEF 982
SC G+ L+ + LC +N WS P C+A+ G ++G + T LS Y E
Sbjct: 2742 SCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYEC 2801
Query: 983 YPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPP-TI 1041
P + ++ T + Q + +N +P+ PP +
Sbjct: 2802 DPG-----YVLNGTERRTCQDD----------------KNWDEDEPICIPVDCSSPPVSA 2840
Query: 1042 NAGLYGN---FRAQLRFISDFSISYEGFNITFSEYNLE-----------PCEDPGIPQYG 1087
N + G+ F+ ++ + + EG N C P G
Sbjct: 2841 NGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANG 2900
Query: 1088 SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEG 1146
G ++G +TF C GY L G ++ C G W A +P C CG
Sbjct: 2901 VTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGN--WDAEIPLCKPVNCGPPED---- 2954
Query: 1147 ILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAF 1206
L+ +P + H IQ Q G K++ + G++
Sbjct: 2955 --LAHGFPNGFSFIHG--GHIQYQCFPG---------------YKLHGNSSRRCLSNGSW 2995
Query: 1207 TGASMRGLTLSSTSNQLWLEFNSDTEGTD------------EGFQLV-----------YT 1243
+G+S L ++ +E+ + GTD +GF+L+
Sbjct: 2996 SGSSPSCLPCRCSTPV--IEYGT-VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQW 3052
Query: 1244 SFELSHCED------PGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERR 1297
S HCE P IP IS+ + + I Y C GY + GSS L C E+
Sbjct: 3053 SSGFPHCEHTSCGSLPMIP--NAFISETSSWKENVITYSCRSGYVIQGSSDLICT--EKG 3108
Query: 1298 AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCM--WMIEVDPGNIVSLQFLA 1355
W P P C G ++ + + + LRC+ + ++ D +
Sbjct: 3109 VWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGR 3168
Query: 1356 FDTEASHDILRVWDGP-----PENDMLL----------KEISGSLIPEGIHSTLNIVTIQ 1400
+ E R+ P PEN + +++S S +NI Q
Sbjct: 3169 WFPE------RISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQ 3222
Query: 1401 FDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEE 1460
D + + F+ + S V +C P P +G G T+++QC+PGYEL+G
Sbjct: 3223 LDGTW---EPPFSDESCSPV--SCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNR 3277
Query: 1461 RITCIQVENRYFWQPSPPVC 1480
C ENR W +C
Sbjct: 3278 ERVC--QENRQ-WSGGVAIC 3294
Score = 85.5 bits (210), Expect = 9e-16
Identities = 57/216 (26%), Positives = 91/216 (42%), Gaps = 20/216 (9%)
Query: 2629 ECLSSGLWSESETRCLAGHCGIPELIVNGQVIGE--NYGYRDTVVYQCNPGFRLIGSSVR 2686
+C+ + S C HC + NG I N + +C+PGF L+GSS+
Sbjct: 359 DCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 2687 ICQQDHNWSGQLPSCVPVSCGHPGSPIYGR--TSGNGFNFNDVVTFSCNIGYLMQGPTKA 2744
+C + WSG C +C H P +G S + +C+ GY ++G K
Sbjct: 419 LCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKL 478
Query: 2745 QCQANRQWSHPPPMCKVVNCSDPGIPAN--------SKRESKIEHGNFTYGTVVFYDCNP 2796
CQ N QW P P C +CS +P + K+ +K +GT+ + C
Sbjct: 479 TCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAK-------FGTICYVSCRQ 531
Query: 2797 GYFLFG-SSVLICQPNGQWDKPLPECIMIDCGHPGV 2831
G+ L G +L C +G+W+ + + D P +
Sbjct: 532 GFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQI 567
Score = 78.6 bits (192), Expect = 1e-13
Identities = 139/641 (21%), Positives = 224/641 (34%), Gaps = 119/641 (18%)
Query: 738 NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC--------GA 789
N D+F GS+++ C G+ G + C W+G+ P C G+
Sbjct: 1698 NGFHSADDFYAGSTVTYQCNNGYYLL-GDSRMFCT---DNGSWNGVSPSCLDVDECAVGS 1753
Query: 790 PCGGHFSAPS--GVILSPGWPGYYKDSLNCEWVIEAE-PGHSIKITFERFQTELNYDVLE 846
C H S + G + P Y D NC I+ + PG+ E + E
Sbjct: 1754 DCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNP----------ENGHSSGE 1803
Query: 847 VHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 906
++ T + FS L+ T + +G H SC
Sbjct: 1804 IY---------------TVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC-KAVSC 1847
Query: 907 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL-CGG 965
P IP +G F+ GS V++ C+ GY L+ ++ C N WSH P C+ + C
Sbjct: 1848 GKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSS 1907
Query: 966 DVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1025
+G + G +T+ ++ T + + T +G +
Sbjct: 1908 PENINNGKYILSG----------------LTYLSTASYSCDTGYSLQGPSIIECTASGIW 1951
Query: 1026 TQ--PLARLTGSDLPPTI-NAGLYGN---FRAQLRFISDFSISYEGFNI----------- 1068
+ P L PP I +A + GN FR + + + G +
Sbjct: 1952 DRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSR 2011
Query: 1069 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1128
+ + C++P I + S + GD + CS GY L S+++C G+ W
Sbjct: 2012 SDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGK--WVP 2069
Query: 1129 P----LPRCVAE-CGASATNNEGILLS-----------------PNYPLNYENNHECIYS 1166
P +PRC+A C + + IL S + LN EC+
Sbjct: 2070 PEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRG 2129
Query: 1167 IQVQAGKGINISARTFHLAQGDVLKIYDG-KDKTTHLLGAFTGASM-RGLTLSSTSNQLW 1224
Q +S + + G+ I +G + + GA S +G +
Sbjct: 2130 GQWNPSP---MSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKG------ 2180
Query: 1225 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1284
E S E T + + T +S C +P + G+ G S + Y CNPGY
Sbjct: 2181 -EKKSTCEATGQWSSPIPTCHPVS-CGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSV 2238
Query: 1285 GSSLLKCMTGERRAWDYPLPSCIAECG-------GRFKGES 1318
GS + C + PL +CG G KGE+
Sbjct: 2239 GSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2279
Score = 78.2 bits (191), Expect = 1e-13
Identities = 251/1237 (20%), Positives = 406/1237 (32%), Gaps = 316/1237 (25%)
Query: 559 SCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
SCG+P G E G +R++C G++ +G VCQ N W + P+
Sbjct: 2203 SCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPL----- 2257
Query: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDG 676
P+ P G+ N + GS++ N+ ++L + K G
Sbjct: 2258 ---MCVPLDCGKPPPIQNGFMKGEN------FEVGSKVQFFCNEGYELVGDSSWTCQKSG 2308
Query: 677 -------------DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSG-------- 715
PE P+L V LT+ ++ + H + G
Sbjct: 2309 KWNKKSNPKCMPAKCPEPPLL---ENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLP 2365
Query: 716 -RGFNITYNTFGHNECPDP-----GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETI 769
+ +N ++ C P G+PI + GS++ C GF +G T
Sbjct: 2366 SQQWNDSFPVCKIVLCTPPPLISFGVPIPS----SALHFGSTVKYSCVGGFF-LRGNSTT 2420
Query: 770 TCILMDGKVMWSGLIPKC-GAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
C DG WS +P+C C P+G+I G Y +L +PG
Sbjct: 2421 LC-QPDG--TWSSPLPECVPVECPQPEEIPNGIIDVQGL-AYLSTAL-----YTCKPG-- 2469
Query: 829 IKITFERFQTELNYDVLEVHDGPNL-LSPLLGSYNGTQVPQFLFSSSNFIYLLF-TTDNS 886
F+ N L +G L P + + + L ++ L + T
Sbjct: 2470 -------FELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTY 2522
Query: 887 RSNNGFKIH--------------YESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSC 932
N GF++ ++ + N C P +G G D+S G+ + +SC
Sbjct: 2523 SCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSC 2582
Query: 933 DSGYRLSHEEPLLCEKNHWWSHPLPTCDAL-CG-------GD---VRGPSG--------- 972
G++++ CE++ WS +PTC + CG GD ++ G
Sbjct: 2583 FPGFQVAGHAMQTCEES-GWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMM 2641
Query: 973 --TILSPGYPEFYPNSLNCTW----------TVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1020
++P +P ++ ++ TW + + +G V + + + + L+
Sbjct: 2642 EVPYVTP-HPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQ 2700
Query: 1021 ENGSF--TQPLARLTGSDLPPTINAGL-------------YGNFRAQLRFISDFSISYEG 1065
E+G++ + P DLP G Y + SD + E
Sbjct: 2701 EDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLEN 2760
Query: 1066 FNITFSEYNLE--PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGR 1123
+ + E C+ P GS G N+ TL + C GY L GT C
Sbjct: 2761 RKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDD-- 2818
Query: 1124 RVWSAPLPRCV-AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF 1182
+ W P C+ +C + + G + Y E + C
Sbjct: 2819 KNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTC------------------- 2859
Query: 1183 HLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTL-SSTSNQLWLEFNSDTEGTDEGFQLV 1241
+G +L+ + + G+++GA+ + + +T QL N TEG D GF
Sbjct: 2860 --NEGFLLE--GARSRVCLANGSWSGATPDCVPVRCATPPQL---ANGVTEGLDYGFMKE 2912
Query: 1242 YTSFELSHCEDPGIPQFGYKISDQ-------------------------------GHFAG 1270
T HC + I K++ Q G
Sbjct: 2913 VT----FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHG 2968
Query: 1271 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFP 1330
I Y C PGY LHG+S +C++ +W PSC+ C R +P +
Sbjct: 2969 GHIQYQCFPGYKLHGNSSRRCLS--NGSWSGSSPSCL-PC----------RCSTPVIEYG 3015
Query: 1331 YDNNLRCMWMIEVDPGNIVSLQ-FLAFDTEASHDILRVWDGPPENDM---------LLKE 1380
N + D G +Q F F +I DG + L
Sbjct: 3016 TVNG------TDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3069
Query: 1381 ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV----------------ATAC 1424
I + I E N++T Y +SG+ IQ SS + +C
Sbjct: 3070 IPNAFISETSSWKENVIT-------YSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3122
Query: 1425 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQP---SPPVCI 1481
P N G+ V +C GY + + Q + R+F + SP C
Sbjct: 3123 GSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCP 3182
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
P N H H D +VN +S A Y +
Sbjct: 3183 LP--------------ENITHILVHGDD----FSVNRQVSVSCA-----------EGYTF 3213
Query: 1542 DGPD-SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1600
+G + S L G+++ P ES S SC P
Sbjct: 3214 EGVNISVCQLDGTWEP---PFSDESCSPV--------------------------SCGKP 3244
Query: 1601 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTC 1637
+ +G +G Y ST+ Y C+ GY L+G C
Sbjct: 3245 ESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3281
Score = 74.3 bits (181), Expect = 2e-12
Identities = 66/251 (26%), Positives = 95/251 (37%), Gaps = 30/251 (11%)
Query: 2935 GRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGP---SVRQCTANGT 2991
G Q EC A G ++ +G+ S C + S P S C
Sbjct: 315 GLQYECTACPSGT---------YKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREG 365
Query: 2992 WSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS--YMCQPGYTMELNGSRIRTCTIN 3049
+ + C ++ C P NG + N + C PG+ +L GS I C N
Sbjct: 366 YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGF--DLVGSSIILCLPN 423
Query: 3050 GTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYI--CSPGYELSFPAVLTCVGN 3107
G WSG CR TCP Q +G + + + + + + C GY L LTC GN
Sbjct: 424 GLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGN 483
Query: 3108 GTWSGEVPQCLPKFCGDPGIPAQ--------GKREGKSFIYQSEVSFSCNFPFILVGSST 3159
W G P+C+ + C +P GK+ K + + SC FIL G
Sbjct: 484 SQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAK---FGTICYVSCRQGFILSGVKE 540
Query: 3160 RI-CQADGTWS 3169
+ C G W+
Sbjct: 541 MLRCTTSGKWN 551
Score = 74.3 bits (181), Expect = 2e-12
Identities = 49/157 (31%), Positives = 65/157 (41%), Gaps = 10/157 (6%)
Query: 2844 FGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG--SRQES 2901
F + C L+G S C NG WSGS+ +C TC P HG S
Sbjct: 398 FNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCR---VRTCPHLRQPKHGHISCSTR 454
Query: 2902 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGN----PGTTANGKVF 2957
K+T ACD GY L GS++ TC N W G +P C C +
Sbjct: 455 EMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNC 514
Query: 2958 RIDGTTFSSSVIYSCMEGYILSG-PSVRQCTANGTWS 2993
F + SC +G+ILSG + +CT +G W+
Sbjct: 515 GKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 73.6 bits (179), Expect = 3e-12
Identities = 68/245 (27%), Positives = 97/245 (39%), Gaps = 36/245 (14%)
Query: 2696 GQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHP 2755
G + SC+P + SP G TS D V C GY G T
Sbjct: 335 GGISSCIPCPDENHTSPP-GSTSPE-----DCV---CREGYRASGQT------------- 372
Query: 2756 PPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWD 2815
C++V+C P N + +F V C+PG+ L GSS+++C PNG W
Sbjct: 373 ---CELVHCPALKPPENGYFIQNTCNNHFNAACGV--RCHPGFDLVGSSIILCLPNGLWS 427
Query: 2816 KPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWS 2873
C + C H P + +S + + +T +C L G TCQ N W
Sbjct: 428 GSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWD 487
Query: 2874 GSQPHCSGDATGTCGDPG----TPGHGSRQESNFRTKSTVRYACDTGYILHGSEER-TCL 2928
G +P C T P +P + +Q + F T V +C G+IL G +E C
Sbjct: 488 GPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYV--SCRQGFILSGVKEMLRCT 545
Query: 2929 ANGSW 2933
+G W
Sbjct: 546 TSGKW 550
Score = 73.6 bits (179), Expect = 3e-12
Identities = 101/450 (22%), Positives = 169/450 (37%), Gaps = 67/450 (14%)
Query: 556 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 615
E C PG P G G+ ++ + F CQ G++L+G I C E+ +W+ IP C
Sbjct: 1785 EPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1844
Query: 616 PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVK 674
P PE CI + GS++ N + L + +
Sbjct: 1845 VSCGK----------PAIPEN-----GCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLA 1889
Query: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILR-------LEFQADHSMSGRGFNITYNTFGH 727
+ SP + P ++ + +IL + D S +G +I T
Sbjct: 1890 NSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASG 1949
Query: 728 NE-----------CPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDG 776
C +P +A G+NF ++++ C+EG+ G +TI C L DG
Sbjct: 1950 IWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLA-GLDTIEC-LADG 2007
Query: 777 KVMWSGLIPKCGA------PCGGHFSAPSGVILSPGWPGYY---------KDSLNC---- 817
K WS +C A P H S + L YY L C
Sbjct: 2008 K--WSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQG 2065
Query: 818 EWVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNF 876
+WV E + F ++Y +LE + + S+ + F+ ++S
Sbjct: 2066 KWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCME--GFVLNTSAK 2123
Query: 877 IYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGY 936
I + N + + + V C +P ++G G ++S G+ V++SC+ G+
Sbjct: 2124 IECM----RGGQWNPSPMSIQCIPVR---CGEPPSIMNGYASGSNYSFGAMVAYSCNKGF 2176
Query: 937 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD 966
+ E+ CE WS P+PTC + G+
Sbjct: 2177 YIKGEKKSTCEATGQWSSPIPTCHPVSCGE 2206
Score = 72.4 bits (176), Expect = 7e-12
Identities = 56/210 (26%), Positives = 83/210 (39%), Gaps = 30/210 (14%)
Query: 2554 CNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTS--YGST 2611
C +GYR S + C ++ C L P NG I + + +
Sbjct: 362 CREGYRASGQT--------------------CELVHCPALKPPENGYFIQNTCNNHFNAA 401
Query: 2612 AIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQV--IGENYGYRDT 2669
C GF LVGS++ CL +GLWS SE+ C C +G + Y+ T
Sbjct: 402 CGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTT 461
Query: 2670 VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSP----IYGRTSG-NGFNF 2724
+ C+ G+RL GS CQ + W G P CV C P I G F
Sbjct: 462 CLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKF 521
Query: 2725 NDVVTFSCNIGYLMQGPTK-AQCQANRQWS 2753
+ SC G+++ G + +C + +W+
Sbjct: 522 GTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 71.2 bits (173), Expect = 2e-11
Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 12/195 (6%)
Query: 2687 ICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFN--FNDVVTFSCNIGYLMQGPTKA 2744
+C++ + SGQ +C V C P G N N FN C+ G+ + G +
Sbjct: 361 VCREGYRASGQ--TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 2745 QCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSS 2804
C N WS C+V C P + Y T C+ GY L GS
Sbjct: 419 LCLPNGLWSGSESYCRVRTC--PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSD 476
Query: 2805 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLS-----GEKYTFGSTVHYSCTGKRSLL 2859
L CQ N QWD P P C+ C +P + ++S + FG+ + SC L
Sbjct: 477 KLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILS 536
Query: 2860 G-QSSRTCQLNGHWS 2873
G + C +G W+
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 70.1 bits (170), Expect = 4e-11
Identities = 51/200 (25%), Positives = 82/200 (41%), Gaps = 15/200 (7%)
Query: 3058 TCRAVTCPTPPQISNGR-LEGT-NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVP 3115
TC V CP NG ++ T N + + C PG++L +++ C+ NG WSG
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 431
Query: 3116 QCLPKFCGDPGIPAQG--KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSP 3173
C + C P G + +Y++ +C+ + L GS CQ + W G P
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 491
Query: 3174 HCIEPTQTSCENPG---VPRHGSQNNTFGFQVGSVVQFHCKKGHLLQG-STTRTCLPDLT 3229
C+E ++ + P + H F G++ C++G +L G C
Sbjct: 492 RCVERHCSTFQMPKDVIISPHNCGKQPAKF--GTICYVSCRQGFILSGVKEMLRCTTSGK 549
Query: 3230 WS-GIQPECIPHSCKQPETP 3248
W+ G+Q CK E P
Sbjct: 550 WNVGVQAAV----CKDVEAP 565
Score = 70.1 bits (170), Expect = 4e-11
Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 20/195 (10%)
Query: 3148 CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVV 3206
C+ F LVGSS +C +G WSGS +C T C + P+HG + +T +
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRT---CPHLRQPKHGHISCSTREMLYKTTC 462
Query: 3207 QFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANV----VGMDLPSHG 3262
C +G+ L+GS TC + W G +P C+ C + P + G G
Sbjct: 463 LVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFG 522
Query: 3263 YTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVP 3322
+C+ GF L+G E C + W V + KD +P+++ P
Sbjct: 523 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGV------QAAVCKD------VEAPQINCP 570
Query: 3323 DDVFAQNYIWKGSYN 3337
D+ A+ + S N
Sbjct: 571 KDIEAKTLEQQDSAN 585
Score = 67.4 bits (163), Expect = 2e-10
Identities = 102/487 (20%), Positives = 170/487 (34%), Gaps = 66/487 (13%)
Query: 151 FSLRLTSDFAVSAHG-FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYI 209
F L S+ A G + + + +SCG+ + P + T + I YSC +GY+
Sbjct: 3036 FKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYV 3095
Query: 210 LDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTW 269
+ G L C V W P P+C +CG ++ + + + E C
Sbjct: 3096 IQGSSDLICTEKGV----WSQPYPVCEPL-SCGSPPSVANAVATGEAHTYESEVKLRCL- 3149
Query: 270 TIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVT 329
G T+ F ++ + P I S P P N + +H
Sbjct: 3150 -----EGYTMDTDTDTFTCQKDGRWF------PERISCSPKKCPLP--ENITHILVHGDD 3196
Query: 330 DSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPE 389
S +R S A + G + + + ++ S C P PE
Sbjct: 3197 FSVNRQVSVSC------AEGYTFEGVNISVCQLDGTWEPPFSDESCSPVS--CGKPESPE 3248
Query: 390 NGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ 449
+G +GS ++ ST+ + C+ Y L+G + CQ + WS +CK C + L+
Sbjct: 3249 HGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ----WSGGVAICKETRCETPLE 3304
Query: 450 GPSG------TFTSPN--------FPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG 495
+G T PN + + S A C T + + + N I
Sbjct: 3305 FLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIP 3364
Query: 496 YDTLTIGDGGEVGDPRTVLQVLTGSFVP--DLIVSMSSQMWLHLQTDESVGSVGFKVNYK 553
+ L + + D ++ G + +I + W
Sbjct: 3365 ENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSA-------------- 3409
Query: 554 EIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN---I 610
+ EK SCG P I G + D++ + C G+ L G VC EN W++
Sbjct: 3410 KCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICR 3469
Query: 611 PICIFPC 617
+C FPC
Sbjct: 3470 AVCRFPC 3476
Score = 65.5 bits (158), Expect = 9e-10
Identities = 68/272 (25%), Positives = 106/272 (38%), Gaps = 49/272 (18%)
Query: 905 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALC 963
SC P P HG G ++ ST+ + C+ GY L +C++N WS + C + C
Sbjct: 3240 SCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRC 3299
Query: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1023
+ EF + + T G V ++ + + + TENG
Sbjct: 3300 ETPL-------------EFLNGKADIE---NRTTGPNVVYSCNRGYSLEGPSEAHCTENG 3343
Query: 1024 SFTQPLARLTGSDLPPTI----NAGLYGNFRAQLRFISDFSISY---EGFNI-------- 1068
+++ P+ + P NA L ++ F D ++S EGF +
Sbjct: 3344 TWSHPVPLCKPNPCPVPFVIPENALL-----SEKEFYVDQNVSIKCREGFLLQGHGIITC 3398
Query: 1069 --------TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1120
T ++ C P + G ++ GD +T+SC SGY LEG +CL
Sbjct: 3399 NPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLE 3458
Query: 1121 GGRRVWSAPLPRCVAECGASATNNEGILLSPN 1152
G W++P P C A C N GI PN
Sbjct: 3459 NG--TWTSP-PICRAVCRFPCQNG-GICQRPN 3486
Score = 60.5 bits (145), Expect = 3e-08
Identities = 141/655 (21%), Positives = 220/655 (33%), Gaps = 99/655 (15%)
Query: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
SCG P G F G + Y C GY L G ++ C N SW+ P C
Sbjct: 1689 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNG----SWNGVSPSCL 1744
Query: 237 -----------AEDACGGTMRGSSGIISSPSFPNEYHNNAD---CTWTIVAEPGDTISLI 282
+E A + GS P + + N A+ C E G + I
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEI 1804
Query: 283 FT-----DFQMEEKYDYLEI------EGSEPPTI--WLSGMNIPPPIISNKNWLR-LHFV 328
+T F +E Y + + E E + + ++ P I + L F
Sbjct: 1805 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1864
Query: 329 TDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNL-CPDPGE 387
S YR ++G+ L K++S + + C P
Sbjct: 1865 FGSKVTYRC--------------NKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPEN 1910
Query: 388 PENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSN 447
NGK I S + ST +SCD Y LQG I C W P C + CG
Sbjct: 1911 INNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC----TASGIWDRAPPACHLVFCGEP 1966
Query: 448 LQGPSGTFTSPNFPFQYDSNAQCV--WVITAVNTNKVIQ----INFEEFDLEIGYDTLTI 501
T NF F+ C + + ++T + + ++ L + D I
Sbjct: 1967 PAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPI 2026
Query: 502 GDGGEVGDPRTVLQVLTGSFVPD-LIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
D + + + D ++ +SQ+ + Q + V G + C
Sbjct: 2027 VDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQ-GKWVPPEG--QDMPRCIAHFC 2083
Query: 561 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
P + Y I E F+ V+ F+C GF L I C QW+ + P+ I C
Sbjct: 2084 EKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-PMSI-QC 2141
Query: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 676
+ P+ P GY + N + G+ + S N F ++ + G
Sbjct: 2142 I-----PVRCGEPPSIMNGYASGSNYSF------GAMVAYSCNKGFYIKGEKKSTCEATG 2190
Query: 677 D-SPESPILGTFTGAEVP-------SHLTSNSHILRLEFQADHSMSGRG---FNITYNTF 725
S P + E P H T + +Q + G F N
Sbjct: 2191 QWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRH 2250
Query: 726 GHNECPDPGIPI---------NARRFGDNFQLGSSISVICEEGFIKTQGTETITC 771
H+E P +P+ N G+NF++GS + C EG+ + G + TC
Sbjct: 2251 WHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGY-ELVGDSSWTC 2304
Score = 58.5 bits (140), Expect = 1e-07
Identities = 75/307 (24%), Positives = 110/307 (35%), Gaps = 43/307 (14%)
Query: 2866 CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGS-EE 2924
C+ + G Q C+ +GT G+PG S S + + GS
Sbjct: 307 CEKGYYGKGLQYECTACPSGTYKPEGSPGGIS---------SCIPCPDENHTSPPGSTSP 357
Query: 2925 RTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT---FSSSVIYSCMEGYILSGP 2981
C+ + C+ V C NG + I T F+++ C G+ L G
Sbjct: 358 EDCVCREGYRASGQTCELVHCPALKPPENG--YFIQNTCNNHFNAACGVRCHPGFDLVGS 415
Query: 2982 SVRQCTANGTWSGTLPNCTIISCGDPGIPANG--------LRYGDDYVVGQNVSYMCQPG 3033
S+ C NG WSG+ C + +C P +G + Y +V C G
Sbjct: 416 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA------CDEG 469
Query: 3034 YTMELNGSRIRTCTINGTWSGVMPTCRAVTCPT---PPQI----SNGRLEGTNFDWGFSI 3086
Y +E GS TC N W G P C C T P + N + F +I
Sbjct: 470 YRLE--GSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFG---TI 524
Query: 3087 SYI-CSPGYELS-FPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEV 3144
Y+ C G+ LS +L C +G W+ V + K P I E K+ Q
Sbjct: 525 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSA 584
Query: 3145 SFSCNFP 3151
+ + P
Sbjct: 585 NVTWQIP 591
Score = 58.2 bits (139), Expect = 1e-07
Identities = 69/283 (24%), Positives = 99/283 (34%), Gaps = 58/283 (20%)
Query: 175 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
S C P P G L T +G ++YSC G+IL G C+ N W P
Sbjct: 2714 SIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLEN----RKWSGASPR 2769
Query: 235 CRA------EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQM 288
C A G+++GS+ S T +PG + +
Sbjct: 2770 CEAISCKKPNPVMNGSIKGSNYTYLS-------------TLYYECDPG----YVLNGTER 2812
Query: 289 EEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
D + EP I + + PP+ +N + RG Y +K I
Sbjct: 2813 RTCQDDKNWDEDEPICIPVDCSS--PPV-------------SANGQVRG--DEYTFQKEI 2855
Query: 349 DFK-SRGFKLFPGKDNSNKFSILNEGGIKTASN-----LCPDPGEPENGKRIGSDFSLGS 402
++ + GF L + + L G A+ C P + NG G D+
Sbjct: 2856 EYTCNEGFLL----EGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMK 2911
Query: 403 TVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCG 445
V F C E Y+L GA +TCQ W P+CK CG
Sbjct: 2912 EVTFHCHEGYILHGAPKLTCQSDGN----WDAEIPLCKPVNCG 2950
Score = 47.8 bits (112), Expect = 2e-04
Identities = 88/446 (19%), Positives = 142/446 (31%), Gaps = 105/446 (23%)
Query: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
++ SC P G + G+ + + Y C GY+L+G + TC + +WD P
Sbjct: 2771 EAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTC----QDDKNWDEDEP 2826
Query: 234 ICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYD 293
IC D C ++G + + + C + E + + D
Sbjct: 2827 ICIPVD-CSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPD 2885
Query: 294 YLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSR 353
+ + + PP + + VT+ Y K + F
Sbjct: 2886 CVPVRCATPPQL-------------------ANGVTE--------GLDYGFMKEVTFHCH 2918
Query: 354 GFKLFPGKDNSNKFSILNEGGIKTASNLCP--DPGEPE---NGKRIGSDFSLGSTVQFSC 408
+ G + K + ++G LC + G PE +G G F G +Q+ C
Sbjct: 2919 EGYILHG---APKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQC 2975
Query: 409 DEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNA 468
Y L G S C +WS P C C + + GT +F +
Sbjct: 2976 FPGYKLHGNSSRRCLS----NGSWSGSSPSCLPCRCSTPVI-EYGTVNGTDFDCGKAARI 3030
Query: 469 QCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVS 528
QC F+ F L +G +T G+
Sbjct: 3031 QC----------------FKGFKL-LGLSEITCEADGQ---------------------- 3051
Query: 529 MSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGD-PGTPLYGIREGDGFSNRDVLRFECQ 587
W S GF E SCG P P I E + +V+ + C+
Sbjct: 3052 -----W----------SSGF----PHCEHTSCGSLPMIPNAFISETSSW-KENVITYSCR 3091
Query: 588 FGFELIGEKSIVCQENNQWSANIPIC 613
G+ + G ++C E WS P+C
Sbjct: 3092 SGYVIQGSSDLICTEKGVWSQPYPVC 3117
Score = 47.0 bits (110), Expect = 3e-04
Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 17/141 (12%)
Query: 2465 CSTPESPPHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2523
C P HG+I T L + ACD G+RL G C+ G WD P P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQ----GNSQWDGPEPRC 493
Query: 2524 QAISCG---IPK----APTNGGILTTDYLVGTRVTYFCNDGYRLSS-KELTTAVCQSDGT 2575
C +PK +P N G + GT C G+ LS KE+ C + G
Sbjct: 494 VERHCSTFQMPKDVIISPHNCGKQPAKF--GTICYVSCRQGFILSGVKEMLR--CTTSGK 549
Query: 2576 WSNHNKTPRCVVISCGELPTP 2596
W+ + C + ++ P
Sbjct: 550 WNVGVQAAVCKDVEAPQINCP 570
Score = 45.8 bits (107), Expect = 7e-04
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)
Query: 3196 NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANV-V 3254
NT + C G L GS+ CLP+ WSG + C +C P H ++
Sbjct: 392 NTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISC 451
Query: 3255 GMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3297
+ T + C G+ L G++ C+ ++ W G P C
Sbjct: 452 STREMLYKTTCLVACDEGYRLE-GSDKLTCQGNSQWDGPEPRC 493
Score = 45.1 bits (105), Expect = 0.001
Identities = 97/424 (22%), Positives = 157/424 (37%), Gaps = 50/424 (11%)
Query: 389 ENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL 448
E G G+DF G + C + + L G ITC E WS P C+ +CGS
Sbjct: 3013 EYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITC----EADGQWSSGFPHCEHTSCGSLP 3068
Query: 449 QGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGY--DTLTIGDGGE 506
P+ + + + N + + + VIQ + + E G + +
Sbjct: 3069 MIPNAFISETS---SWKENV----ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3121
Query: 507 VGDPRTVLQ-VLTG-SFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPG 564
G P +V V TG + + V + + TD + + E+ SC
Sbjct: 3122 CGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFP-ERISCSPKK 3180
Query: 565 TPL-----YGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 619
PL + + GD FS + C G+ G VCQ + W P
Sbjct: 3181 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEP-------PFSD 3233
Query: 620 NFTAPM--GTVLSPDYPEGYGNNLNCIWTII--SDPGSRIHLSFNDFDLESQ--FDFLAV 673
+P+ G SP++ G+ TII +PG + + E++ +A+
Sbjct: 3234 ESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAI 3293
Query: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYN-TFGH---- 727
E+P+ A++ + T + + +S+ G + T N T+ H
Sbjct: 3294 CKETRCETPLEFLNGKADIENRTTGPNVVYSCN--RGYSLEGPSEAHCTENGTWSHPVPL 3351
Query: 728 ---NECPDPG-IPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 783
N CP P IP NA F + ++S+ C EGF+ QG ITC + W+
Sbjct: 3352 CKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFL-LQGHGIITC---NPDETWTQT 3407
Query: 784 IPKC 787
KC
Sbjct: 3408 SAKC 3411
Score = 42.0 bits (97), Expect = 0.011
Identities = 17/59 (28%), Positives = 28/59 (47%)
Query: 556 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 614
E+ SCG P G D F + ++C G+ L+G+ + C +N W+ P C+
Sbjct: 1686 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCL 1744
Score = 41.6 bits (96), Expect = 0.014
Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 1099 TLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPN 1152
T +C GYRLEG+ ++ C G + W P PRCV ++ + +++SP+
Sbjct: 461 TCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 39.3 bits (90), Expect = 0.070
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 2135 DFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CG 2180
D G ++ C PG+ L+GN CL+ W PLP CE + CG
Sbjct: 1647 DLKPGSKVNLFCDPGFQLVGNPVQYCLN--QGQWTQPLPHCERISCG 1691
Score = 38.9 bits (89), Expect = 0.091
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 4/99 (4%)
Query: 1947 SCPEPQTPSSG-IKIGDRYMVGDVVSF-QCDQGYSLQGHSHITCMPGPVRRWNYPIPICL 2004
+CP + P G I R M+ CD+GY L+G +TC +W+ P P C+
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGN--SQWDGPEPRCV 494
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF 2043
+ VI+SP G P+ ++ GF
Sbjct: 495 ERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGF 533
Score = 38.9 bits (89), Expect = 0.091
Identities = 18/52 (34%), Positives = 24/52 (46%)
Query: 926 STVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSP 977
+T +CD GYRL + L C+ N W P P C + P I+SP
Sbjct: 460 TTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 38.9 bits (89), Expect = 0.091
Identities = 16/46 (34%), Positives = 22/46 (47%)
Query: 586 CQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSP 631
C G+ L G + CQ N+QW P C+ S F P ++SP
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 38.1 bits (87), Expect = 0.16
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 8/57 (14%)
Query: 185 PKGVLYG----TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
PK +L G T G + YSC G+ L+G LTC+ T WD P C A
Sbjct: 2501 PKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCL----ETGDWDVDAPSCNA 2553
Score = 37.4 bits (85), Expect = 0.27
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 2105 KQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFT--VGQTISFECFPGYTLIGNSALTCL 2161
++G+ Q +L CP +P NG+ I N C PG+ L+G+S + CL
Sbjct: 363 REGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCL 421
Score = 37.4 bits (85), Expect = 0.27
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 382 CPDPGEPENGKRIGS--DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
CP +P++G S + +T +CDE Y L+G+ +TCQ ++ W P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQ----WDGPEPRC 493
Query: 440 KVKTCGSNLQGPSGTFTSPN 459
+ C S Q P SP+
Sbjct: 494 VERHC-STFQMPKDVIISPH 512
Score = 36.2 bits (82), Expect = 0.59
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 6/65 (9%)
Query: 178 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
C +P G + G + G I YSC G+ + GH TC + W +P C
Sbjct: 2556 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTC-----EESGWSSSIPTCMP 2610
Query: 238 EDACG 242
D CG
Sbjct: 2611 ID-CG 2614
Score = 35.4 bits (80), Expect = 1.0
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Query: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSP 805
V C+EG+ + +G++ +TC G W G P+C F P VI+SP
Sbjct: 464 VACDEGY-RLEGSDKLTC---QGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 34.7 bits (78), Expect = 1.7
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Query: 1236 EGFQLVYTSFELSHCEDPGIPQFGYKISD--QGHFAGSTIIYGCNPGYTLHGSSLLKCM 1292
EG++ + EL HC P+ GY I + HF + + C+PG+ L GSS++ C+
Sbjct: 364 EGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR-CHPGFDLVGSSIILCL 421
Score = 32.7 bits (73), Expect = 6.5
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 1271 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCI 1307
+T + C+ GY L GS L C + WD P P C+
Sbjct: 460 TTCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCV 494
Score = 32.3 bits (72), Expect = 8.5
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
Query: 203 SCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSP 255
+C GY L+G +LTC NS WD P P C E C T + +I SP
Sbjct: 465 ACDEGYRLEGSDKLTCQGNS----QWDGPEPRC-VERHC-STFQMPKDVIISP 511
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 401 bits (1030), Expect = e-111
Identities = 468/1856 (25%), Positives = 684/1856 (36%), Gaps = 337/1856 (18%)
Query: 1594 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
Query: 1653 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1707
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 1708 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1762
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
Query: 1763 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1812
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
Query: 1813 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1871
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
Query: 1872 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 1931
++ S+ +SL + S + V
Sbjct: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
Query: 1932 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 1982
F CP P +G G + + G V++ CD + L G
Sbjct: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
Query: 1983 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
S I C P W+ P P C G++ P
Sbjct: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
Query: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2100
H F T+T + T + P+ FS T +L + S
Sbjct: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
Query: 2101 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2159
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
Query: 2160 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2217
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
Query: 2218 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2264
F ++ IY D + +W GP P + + S++S +
Sbjct: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
Query: 2265 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2314
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
Query: 2315 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2374
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
Query: 2375 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
Query: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2488
+ +C +P P+G TG L V
Sbjct: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKAV 896
Query: 2489 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2533
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
Query: 2534 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGEL 2593
TN +D+ +GT + Y C Y +T C + WS+ C SC
Sbjct: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
Query: 2594 PTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCG 2649
P P NG + T GS ++C G L+G + EC+ SG WS C CG
Sbjct: 1008 PDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCG 1067
Query: 2650 IPELIVNGQVIG---ENYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSG 2696
+P I NG I EN+ Y V Y+CN G F L+G C + + WSG
Sbjct: 1068 LPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSG 1127
Query: 2697 QLPSC-VPVSCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWS 2753
P C +P C P + I + + F+ N+VV F C G++M+GP + +CQA +W
Sbjct: 1128 PAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
Query: 2754 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ 2813
P C V P I S NF+ G VFY C PGY L G++ L C P G
Sbjct: 1188 PELPSCSRVCQPPPEILHGEHTPS--HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD 1245
Query: 2814 WDKPLPECIMIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 2871
W P C + C +P VL G+ V + C L G S C L G
Sbjct: 1246 WSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
Query: 2872 ---WSGSQPHCSGDATGTCGDPG---TPGHGSRQESNFRTKSTVRYACD------TGYIL 2919
W+ S P C C +P H + + Y CD + L
Sbjct: 1306 RSLWNNSVPVCEHI---FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 2920 HGSEERTCLA----NGSWTGRQPECK-AVQCGNPGTTAN----GKVFRIDGTTF--SSSV 2968
G C + NG W+ P C+ +V+ G+ T I+ F +S+
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSL 1422
Query: 2969 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGL-RYGDDYVVGQNVS 3027
Y C GY S+ C N WS NC SCG P P NG+ D G V+
Sbjct: 1423 NYECRPGYFGKMFSI-SCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1481
Query: 3028 YMCQPGYTMELNGSRIRTCTING---TWSGVMPTCRAVTCPTPPQISNGRL---EGTNFD 3081
Y C G+ L GS TC ++G TW P C ++C PP ISNG T+F
Sbjct: 1482 YSCNEGF--RLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFH 1539
Query: 3082 WGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQCL-PKFCGDPGIPAQ 3130
G ++Y C G +EL + C G WS P+C+ C P +
Sbjct: 1540 NGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENA 1599
Query: 3131 GKREG-KSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV 3188
+ G +SF +E + F C F++VGS T CQ +G W PHC C+ P
Sbjct: 1600 IRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC----SRVCQPPPE 1655
Query: 3189 PRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-- 3244
HG ++ F G V + C+ + L+G+ + C P WS P C SC
Sbjct: 1656 ILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL 1715
Query: 3245 PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAG-GTEHRVCRSDNT-WTGKVPICE 3298
+ P ++ ++L G + + C GF L G H V W VP+CE
Sbjct: 1716 GQLPHGRVLLPLNL-QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Score = 305 bits (780), Expect = 7e-82
Identities = 267/919 (29%), Positives = 381/919 (41%), Gaps = 110/919 (11%)
Query: 2465 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2520
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
Query: 2521 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2578
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
Query: 2579 HNKTPRCVVISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRE 2629
N+TP C I CG PT NG+ I T YGS + C+ G F LVG
Sbjct: 156 -NETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIY 214
Query: 2630 CLSS----GLWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIG 2682
C S+ G+WS +C+ + P + NG ++ +N + + V ++C PGF + G
Sbjct: 215 CTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKG 274
Query: 2683 SSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG-RTSGNGFNFN--DVVTFSCNIGYLMQ 2739
CQ + W +LPSC V C P ++ RT + NF+ V +SC GY ++
Sbjct: 275 PRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 333
Query: 2740 GPTKAQCQANRQWSHPPPMCKVVNCSD-PGIPANSKRESKIEHGNFTYGTVVFYDCNPGY 2798
G +C WS P C+V +C D G N + + N G V + C+ G+
Sbjct: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPV---NLQLGAKVDFVCDEGF 390
Query: 2799 FLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSC 2852
L GSS C G W+ +P C I C P V PN +G E + FG TV+Y+C
Sbjct: 391 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC 450
Query: 2853 T------GKRSLLGQSSRTC----QLNGHWSGSQPHCSGDATGTCGDPGTPGH------- 2895
L+G+S+ C Q NG WS P C G G P H
Sbjct: 451 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLK 505
Query: 2896 GSRQESNFRTKSTVRYACDTGYILHGSE-ERTCLANGSWTGRQPECKAVQCGNPGTTANG 2954
S+F ++++Y C Y +G TCL N W+ + CK C P NG
Sbjct: 506 TQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNG 563
Query: 2955 KVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPA 3011
V I S + YSC G+ L G S +C +G WS P C I CG P A
Sbjct: 564 MVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIA 623
Query: 3012 NG---LRYGDDYVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCR 3060
NG +++ G V+Y C PG EL G CT N G WSG P C
Sbjct: 624 NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 683
Query: 3061 AVTCPTPPQISNGRLEGTN---FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117
TPP + NG L N F + + C PG+ + P + C W E+P C
Sbjct: 684 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 743
Query: 3118 LPKFCGDPG---IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPH 3174
+ C P + +R+ +F EV +SC + L G+++ C G WS ++P
Sbjct: 744 -SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT 802
Query: 3175 CIEPTQTSCEN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTW 3230
C SC++ G +G Q+G+ V F C +G L+GS+ C+ + W
Sbjct: 803 C---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLW 859
Query: 3231 SGIQPECIPHSCKQPETPAHANVVG--MDLPSHGYTLIYTCQP------GFFLAGGTEHR 3282
+ P C C P + G +++ G + YTC P F L G + R
Sbjct: 860 NSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR 919
Query: 3283 VCRSD----NTWTGKVPIC 3297
C SD W+ P C
Sbjct: 920 -CTSDPQGNGVWSSPAPRC 937
Score = 291 bits (744), Expect = 1e-77
Identities = 240/829 (28%), Positives = 335/829 (40%), Gaps = 96/829 (11%)
Query: 2543 DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGN-K 2601
++ +GT + Y C GY S + +C + W+ RC SC P P NG
Sbjct: 62 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWTGAKD--RCRRKSCRNPPDPVNGMVH 116
Query: 2602 IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQ 2658
+ +GS ++C G+ L+GS+ C+ SG +W C CG+P I NG
Sbjct: 117 VIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGD 176
Query: 2659 VIG---ENYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PV 2704
I EN+ Y V Y+CNPG F L+G C + + WSG P C+ P
Sbjct: 177 FISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN 236
Query: 2705 SCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2762
C P + I + + F+ N+VV F C G++M+GP + +CQA +W P C V
Sbjct: 237 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
Query: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
C P +++R + + NF+ G VFY C PGY L G++ + C P G W P C
Sbjct: 297 -CQPPPDVLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE 354
Query: 2823 MIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQP 2877
+ C + VL G+ V + C L G S+ C L G W+ S P
Sbjct: 355 VKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 414
Query: 2878 HCSGDATGTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA 2929
C + P P H + F TV Y CD T + L G C +
Sbjct: 415 VC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTS 472
Query: 2930 ----NGSWTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGY 2976
NG W+ P C + C P T N F I +S+ Y C Y
Sbjct: 473 DPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY 527
Query: 2977 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYT 3035
P C N WS C SC P P NG+ + D VG ++Y C G+
Sbjct: 528 -YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH- 585
Query: 3036 MELNGSRIRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYI 3089
L G C ++G WS P C+ + C PP I+NG T NF +G ++Y
Sbjct: 586 -RLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYR 644
Query: 3090 CSPG------YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKRE 3134
C+PG +EL + C N G WSG PQC +P C P GI R
Sbjct: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR- 703
Query: 3135 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG-- 3192
F V F C F++ G CQA W P C C+ P H
Sbjct: 704 -SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAER 758
Query: 3193 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHA 3251
+Q + F G V + C+ G+ L+G+ + C P WS P C SC +
Sbjct: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 818
Query: 3252 NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3298
V+ G + + C GF L G + + ++ W VP+CE
Sbjct: 819 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
Score = 288 bits (736), Expect = 9e-77
Identities = 448/1942 (23%), Positives = 694/1942 (35%), Gaps = 374/1942 (19%)
Query: 1270 GSTIIYGCNPG------YTLHGSSLLKCMTGERRA--WDYPLPSCIAECGGRFKGESSGR 1321
GS + Y CNPG + L G + C + + + W P P CI +G
Sbjct: 188 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 247
Query: 1322 ILSPGYPFPYDNNL---RCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLL 1378
++S N + RC + V Q L RV PP+
Sbjct: 248 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPD----- 302
Query: 1379 KEISGSLIPEGIHSTLNIVTIQFDTD--------FYISKSGFAIQFSSSVATACR---DP 1427
L+ Q D D FY + G+ ++ ++S+ + P
Sbjct: 303 --------------VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
Query: 1428 GVPMNGTRNGD--------GR-------EPGDTVVFQCDPGYELQGEERITCIQVENRYF 1472
P ++ D GR + G V F CD G++L+G C+
Sbjct: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
Query: 1473 WQPSPPVCIAPCGGNLTGSSGFILSPNFPHP------YPHSRDCDWTITVNADYVISLAF 1526
W S PVC + S ++ PN H +P + ++T + D S
Sbjct: 409 WNSSVPVC-----EQIFCPSPPVI-PNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 1527 ISFSI-----EPNYDFLYIYDGPDSNSPLIGSFQD------SKLPERIESSSNTMHLAFR 1575
I S +P + ++ P ++G Q +KL + +S + + +
Sbjct: 463 IGESTIRCTSDPQGNG--VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK 520
Query: 1576 SDGSVSYTG--FHLEYKAKL----------RESCFDPGNIMNG-TRLGMDYKLGSTVTYY 1622
+ Y G F + L R+SC P + +NG + D ++GS + Y
Sbjct: 521 YECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYS 580
Query: 1623 CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVG 1681
C G+ L G+S+ CI+ + W+ P C PCG T + G +S N +N+ G
Sbjct: 581 CTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPPTIANGDFISTNR-ENFHYG 638
Query: 1682 ----HNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLP 1737
+ C K F + G+ + TS D V ++ GP Q + + + + +
Sbjct: 639 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 698
Query: 1738 LSSGNQI-----TIRFTSVGPITAKGFHFVY-QAVPRTSST--QCSSVPEP-------RF 1782
+S + + F KG V QA+ + CS V +P
Sbjct: 699 VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAER 758
Query: 1783 GRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTK 1841
+R + F+ G V + C PGY L G+ ++RC W+ + PTC + C +
Sbjct: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC----TPQGDWSPAAPTCEVKSCDDFM-- 812
Query: 1842 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1901
G +L+ P + L EG ++ S+ +SL
Sbjct: 813 --GQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL------------ 858
Query: 1902 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 1961
+ S + V F CP P +G G
Sbjct: 859 -----------------------WNSSVPVCEQIF-----------CPSPPVIPNGRHTG 884
Query: 1962 ---DRYMVGDVVSFQCDQ------GYSLQGHSHITCMPGPVRR--WNYPIPICLAQCGGA 2010
+ + G V++ CD + L G S I C P W+ P P C
Sbjct: 885 KPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC------- 937
Query: 2011 MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSET 2070
G++ P H F T+T +
Sbjct: 938 -----GILGHCQAPD--------------------HFLFAKLKTQT-------NASDFPI 965
Query: 2071 STVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGF 2130
T + P+ FS T +L + S K+ +SC P NG
Sbjct: 966 GTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKR-----------KSCKTPPDPVNGM 1014
Query: 2131 V-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRCEAL-CGGNITAMN 2187
V + D VG I++ C G+ LIG+S+ C L G + +W+ P C+ + CG T N
Sbjct: 1015 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIAN 1074
Query: 2188 GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----DFITVWDGPDQN 2242
G S + + + G + F ++ IY D + +W GP
Sbjct: 1075 GDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
Query: 2243 S--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQL------ 2288
P + + S++S + + + F G + A
Sbjct: 1132 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 1191
Query: 2289 ---RVCQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA 2344
RVCQPPP + + E + D F G + Y C PG+ L G A L C Q D +
Sbjct: 1192 SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP----QGDWS 1247
Query: 2345 P--PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISV------EKGYNITMFV 2396
P P C V + L G +L P NLQ+ A V KG +++ V
Sbjct: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFP------LNLQLGAKVSFVCDEGFRLKGSSVSHCV 1301
Query: 2397 EFFQTEKEFDVLQVYDGPNIQSPVLI-------SLSGD--YSSAFNITSNGH-------- 2439
+ + V + +P I + SGD Y + T + H
Sbjct: 1302 LVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFN 1361
Query: 2440 ---EVFLQWSAD-HGNN-----KKGFRIRYIAFYCSTPESPPHG---YIISQTGGQLNSV 2487
E ++ ++D HGN + A +C TPE P I+ + +
Sbjct: 1362 LIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTS 1421
Query: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI-LTTDYLV 2546
+ + C G+ GK ++ S W + C+ SCG P P NG + + TD
Sbjct: 1422 LNYECRPGY--FGKMFSI---SCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF 1476
Query: 2547 GTRVTYFCNDGYRLSSKELTTAVCQSDG-TWSNHNKTPRCVVISCGELPTPPNGNKIGT- 2604
G+ V Y CN+G+RL TT + + TW K P C +ISC PT NG+
Sbjct: 1477 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDK--KAPICEIISCEPPPTISNGDFYSNN 1534
Query: 2605 QTSY--GSTAIFTCDLG------FMLVGSAVRECLSS----GLWSESETRCLAGH-CGIP 2651
+TS+ G+ + C G F LVG C S G+WS RC++ + C P
Sbjct: 1535 RTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAP 1594
Query: 2652 ELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP 2709
E+ +V G + + + ++C PGF ++GS CQ + W +LP C V C P
Sbjct: 1595 EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPP 1653
Query: 2710 GSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSD 2766
++G + + F+ V +SC Y ++G C WS P C V +C D
Sbjct: 1654 PEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDD 1713
Query: 2767 PGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ---WDKP 2817
++ HG N G V + C+ G+ L G S C G W+
Sbjct: 1714 --------FLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSS 1765
Query: 2818 LPECIMIDCGHPGVPPNAVLSGEKY---TFGSTVHYSCTGKR------SLLGQSSRTC-- 2866
+P C I C +P N +G + +G + Y+C +L+G+SS C
Sbjct: 1766 VPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTS 1825
Query: 2867 --QLNGHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHG 2921
Q NG WS P C C P +G S + T+ Y CD GY+L G
Sbjct: 1826 DPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVG 1885
Query: 2922 SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT---FSSSVIYSCMEGYIL 2978
C G W+ CK V C P NG ++ + V C +GY L
Sbjct: 1886 KGFIFCTDQGIWSQLDHYCKEVNCSFP-LFMNGISKELEMKKVYHYGDYVTLKCEDGYTL 1944
Query: 2979 SGPSVRQCTANGTWSGTLPNCT 3000
G QC A+ W L CT
Sbjct: 1945 EGSPWSQCQADDRWDPPLAKCT 1966
Score = 285 bits (730), Expect = 4e-76
Identities = 255/932 (27%), Positives = 379/932 (40%), Gaps = 113/932 (12%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
C P P +G + G Q S ++++C +G+RL+G SSA C S WD P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISG-DTVIWDNETPICD 162
Query: 2525 AISCGIPKAPTNGGILTT---DYLVGTRVTYFCNDG------YRLSSKELTTAVCQSD-- 2573
I CG+P TNG ++T ++ G+ VTY CN G + L + D
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 2574 GTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLGFMLVGSAVREC 2630
G WS P+C++ + P NG + S S F C GF++ G +C
Sbjct: 223 GIWS--GPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 2631 LSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2687
+ W E E + C P +++ Q +N+ V Y C PG+ L G++
Sbjct: 281 QALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 2688 CQQDHNWSGQLPSCVPVSC-GHPGSPIYGRT-SGNGFNFNDVVTFSCNIGYLMQGPTKAQ 2745
C +WS P+C SC G + GR V F C+ G+ ++G + +
Sbjct: 340 CTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASY 399
Query: 2746 C---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNP------ 2796
C W+ P+C+ + C P + N + K F +G V Y C+P
Sbjct: 400 CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGK-PLEVFPFGKTVNYTCDPHPDRGT 458
Query: 2797 GYFLFGSSVLIC----QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK-------YTFG 2845
+ L G S + C Q NG W P P C ++ GH P + + + K + G
Sbjct: 459 SFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDFPIG 516
Query: 2846 STVHYSCTGKRSLLGQS-SRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGS-RQESNF 2903
+++ Y C + G+ S TC N WS + C +C P P +G ++
Sbjct: 517 TSLKYEC--RPEYYGRPFSITCLDNLVWSSPKDVCK---RKSCKTPPDPVNGMVHVITDI 571
Query: 2904 RTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPGTTANGKVFRID 2960
+ S + Y+C TG+ L G C+ +G+ W+ + P C+ + CG P T ANG +
Sbjct: 572 QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 631
Query: 2961 GTTF--SSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLPNCTIISCGDPG 3008
F S V Y C G + L G CT+N G WSG P C I + P
Sbjct: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 691
Query: 3009 IPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP 3065
NG+ D+ + + + V + CQPG+ M+ G R C W +P+C V C
Sbjct: 692 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEPELPSCSRV-CQ 748
Query: 3066 TPPQISNG---RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC 3122
PP + + + + NF G + Y C PGY+L A + C G WS P C K C
Sbjct: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 808
Query: 3123 GDPGIPAQGKREGKSFIYQ------SEVSFSCNFPFILVGSSTRICQADG---TWSGSSP 3173
D G+ ++ ++V F C+ F L GSS C G W+ S P
Sbjct: 809 DD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 864
Query: 3174 HCIEPTQTSCENPGVPRHGSQNN------TFGFQVGSVVQFHCKKGHL--LQGSTTRTCL 3225
C Q C +P V +G FG V H +G L G +T C
Sbjct: 865 VC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCT 921
Query: 3226 PDL----TWSGIQPEC-IPHSCKQPETPAHANVV----GMDLPSHGYTLIYTCQPGFFLA 3276
D WS P C I C+ P+ A + D P G +L Y C+P ++
Sbjct: 922 SDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-GTSLKYECRPEYY-- 978
Query: 3277 GGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3308
G C + W+ +C+ S DP
Sbjct: 979 GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDP 1010
Score = 278 bits (711), Expect = 7e-74
Identities = 243/858 (28%), Positives = 342/858 (39%), Gaps = 118/858 (13%)
Query: 2467 TPESPPHGYIISQTGG--QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
TP + +G ++S LN VV + C GF + G C+ + W+ +P+C
Sbjct: 1139 TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ----ALNKWEPELPSCS 1194
Query: 2525 AISCGIPKAPTNGGILTT---DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
+ C P +G + ++ G V Y C GY L + + C G WS +
Sbjct: 1195 RV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDL--RGAASLHCTPQGDWSP--E 1249
Query: 2582 TPRCVVISCGE-LPTPPNGNKI-GTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LW 2636
PRC V SC + L P+G + G+ F CD GF L GS+V C+ G LW
Sbjct: 1250 APRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLW 1309
Query: 2637 SESETRCLAGHCGIPELIVNGQVIGENYG---YRDTVVYQCNPG------FRLIGSSVRI 2687
+ S C C P I+NG+ G G Y + Y C+P F LIG S
Sbjct: 1310 NNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIR 1369
Query: 2688 CQQDHN----WSGQLPSC-VPVSCGHPGSPIYGRTSGNGFNFNDV-------VTFSCNIG 2735
C D + WS P C + V GH +P + ND + + C G
Sbjct: 1370 CTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPG 1429
Query: 2736 YLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2795
Y + C N WS C+ +C P P N + +G+ V Y CN
Sbjct: 1430 YFGK-MFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDT---QFGSTVNYSCN 1485
Query: 2796 PGYFLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGEKYTF-------G 2845
G+ L GS C +G WDK P C +I C PP + +G+ Y+ G
Sbjct: 1486 EGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE----PPPTISNGDFYSNNRTSFHNG 1541
Query: 2846 STVHYSC-TGKRS-----LLGQSSRTCQLN----GHWSGSQPHCSGDATGTCGDPGT--- 2892
+ V Y C TG L+G+ S C G WS P C +T C P
Sbjct: 1542 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCI--STNKCTAPEVENA 1599
Query: 2893 ---PGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG 2949
PG+ S F +R+ C G+++ GS C NG W + P C V C P
Sbjct: 1600 IRVPGN----RSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPP 1654
Query: 2950 TTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGD- 3006
+G+ FS V YSC Y L G + CT G WS P CT+ SC D
Sbjct: 1655 EILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF 1714
Query: 3007 -PGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAV 3062
+P + + +G VS++C G+ L G C + G W+ +P C +
Sbjct: 1715 LGQLPHGRVLLPLNLQLGAKVSFVCDEGF--RLKGRSASHCVLAGMKALWNSSVPVCEQI 1772
Query: 3063 TCPTPPQISNGRLEGTNF---DWGFSISYICS--PGYELSFPAV----LTCV----GNGT 3109
CP PP I NGR GT F +G ISY C P ++F + + C GNG
Sbjct: 1773 FCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGV 1832
Query: 3110 WSGEVPQC---LPKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQ 3163
WS P+C +P C P G G ++ +S+ C+ ++LVG C
Sbjct: 1833 WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCT 1892
Query: 3164 ADGTWSGSSPHCIEPTQTSCENP----GVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGS 3219
G WS +C E +C P G+ + + + G V C+ G+ L+GS
Sbjct: 1893 DQGIWSQLDHYCKE---VNCSFPLFMNGISKELEMKKVYHY--GDYVTLKCEDGYTLEGS 1947
Query: 3220 TTRTCLPDLTWSGIQPEC 3237
C D W +C
Sbjct: 1948 PWSQCQADDRWDPPLAKC 1965
Score = 270 bits (689), Expect = 2e-71
Identities = 242/925 (26%), Positives = 370/925 (40%), Gaps = 117/925 (12%)
Query: 2465 CSTPESPPHGYIISQTGGQLN--SVVRWACDRG------FRLVGKSSAVCRKSSYGYHAW 2516
C P + +G IS + SVV + C+ G F LVG+ S C + W
Sbjct: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
Query: 2517 DAPVPACQAISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQS 2572
P P C + P NG IL +D + + V + C G+ + CQ+
Sbjct: 1126 SGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK--CQA 1182
Query: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDLGFMLVGS 2625
W + SC + PP G T S G ++C+ G+ L G+
Sbjct: 1183 LNKWEPE-------LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
Query: 2626 AVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS 2683
A C G WS RC C + +L + N V + C+ GFRL GS
Sbjct: 1236 ASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGS 1295
Query: 2684 SVRICQ---QDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN---GFNFNDVVTFSCN---- 2733
SV C W+ +P C + C +P + + GR +G + ++++C+
Sbjct: 1296 SVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPD 1355
Query: 2734 --IGYLMQGPTKAQCQA----NRQWSHPPPMCKVV----NCSDPGIPANSKRESKIEHGN 2783
+ + + G + +C + N WS P P C++ +C P + I
Sbjct: 1356 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFE 1415
Query: 2784 FTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 2841
F GT + Y+C PGYF +F S C N W C CG P P N ++
Sbjct: 1416 FPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
Query: 2842 YT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPGTPGHG- 2896
T FGSTV+YSC L+G S TC ++G+ W P C +C P T +G
Sbjct: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPPPTISNGD 1529
Query: 2897 --SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECKAV- 2943
S ++F + V Y C TG + L G C + G W+ P C +
Sbjct: 1530 FYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTN 1589
Query: 2944 QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2999
+C P R+ G T + + + C G+++ G QC NG W LP+C
Sbjct: 1590 KCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 1646
Query: 3000 TIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3057
+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G WS P
Sbjct: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQGDWSPEAP 1704
Query: 3058 TCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSG 3112
C +C Q+ +GR L N G +S++C G+ L + CV G W+
Sbjct: 1705 RCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNS 1764
Query: 3113 EVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVGSSTRICQ 3163
VP C FC +P G+ G F Y E+S++C+ F L+G S+ C
Sbjct: 1765 SVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCT 1824
Query: 3164 AD----GTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQ 3217
+D G WS +P C +C +P ++G + + G + + C G+LL
Sbjct: 1825 SDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLV 1884
Query: 3218 GSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTLIYTCQPG 3272
G C WS + C +C P N + +L +G + C+ G
Sbjct: 1885 GKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYVTLKCEDG 1941
Query: 3273 FFLAGGTEHRVCRSDNTWTGKVPIC 3297
+ L G + C++D+ W + C
Sbjct: 1942 YTLEGSPWSQ-CQADDRWDPPLAKC 1965
Score = 80.1 bits (196), Expect = 4e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
Query: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 1516 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 1550
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 1551 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 1600
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 620
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 1601 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 1648
Query: 621 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 678
P +L ++ + +N + PG + S +DL GD S
Sbjct: 1649 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
Query: 679 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 738
PE+P + + L +L L
Sbjct: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 1727
Query: 739 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 1728 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 1769
Score = 71.2 bits (173), Expect = 2e-11
Identities = 82/293 (27%), Positives = 123/293 (41%), Gaps = 33/293 (11%)
Query: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
SC P P G+++ T VG +I YSC TG+ L GH CI S NTA W PIC
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSTKPPIC 1061
Query: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYL 295
+ CG ++G S + N ++ + + G + F++ +
Sbjct: 1062 Q-RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV------FELVGEPSIY 1114
Query: 296 EIEGSEPPTIWLSGMNIPPPIISNK----NWLRLHFVTDSNHRYRGFSAPYQVKKAIDFK 351
+ IW SG P II NK N V+D+ + + + + ++F+
Sbjct: 1115 CTSNDDQVGIW-SG-PAPQCIIPNKCTPPNVENGILVSDNR-------SLFSLNEVVEFR 1165
Query: 352 SRGFKLFPGKDNSNKFSILN--EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQF 406
+ + G K LN E + + S +C P E +G+ S +FS G V +
Sbjct: 1166 CQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFY 1224
Query: 407 SCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 458
SC+ Y L+GA S+ C + WS P C VK+C L Q P G P
Sbjct: 1225 SCEPGYDLRGAASLHCTPQGD----WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
Score = 70.5 bits (171), Expect = 3e-11
Identities = 75/279 (26%), Positives = 116/279 (41%), Gaps = 34/279 (12%)
Query: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
Query: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 290
+ CG ++G S + N +H + T+ PG +F
Sbjct: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
Query: 291 KYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
D + I P + PP + +N + V+D+ + + + + ++F
Sbjct: 668 NDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSLNEVVEF 714
Query: 351 KSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQ 405
+ + + G K LN E + + S +C PD E +R +FS G V
Sbjct: 715 RCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVF 773
Query: 406 FSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
+SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 774 YSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 808
Score = 69.7 bits (169), Expect = 5e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1210
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
+ +N + PG + S +DL GD SPE+P
Sbjct: 1211 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1251
Query: 694 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 753
R ++ G+ +P F N QLG+ +S
Sbjct: 1252 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1283
Query: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 804
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 1284 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1340
Query: 805 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 859
P + S C +P +TF + H SP L
Sbjct: 1341 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1391
Query: 860 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 902
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 1392 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1451
Query: 903 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 956
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 1452 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
Query: 957 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1016
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 1512 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 1558
Query: 1017 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
L+ E + G S PP R IS +
Sbjct: 1559 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 1592
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 1593 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 1647
Query: 1135 AEC 1137
C
Sbjct: 1648 RVC 1650
Score = 68.9 bits (167), Expect = 8e-11
Identities = 74/285 (25%), Positives = 118/285 (41%), Gaps = 34/285 (11%)
Query: 171 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
Query: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----T 284
PIC CG ++G S + N +H + T+ PG +F
Sbjct: 156 NETPIC-DRIPCGLPPTITNGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEP 211
Query: 285 DFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQV 344
D + I P + PP + +N + V+D+ + + +
Sbjct: 212 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSL 258
Query: 345 KKAIDFKSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFS 399
+ ++F+ + + G K LN E + + S +C PD E +R +FS
Sbjct: 259 NEVVEFRCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFS 317
Query: 400 LGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
G V +SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 318 PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 358
Score = 67.8 bits (164), Expect = 2e-10
Identities = 77/295 (26%), Positives = 121/295 (41%), Gaps = 25/295 (8%)
Query: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 1450 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1508
Query: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEP-GDTISLIFTDFQM 288
PIC +C S+G S + +HN T+ P G+ + F++
Sbjct: 1509 KKAPICEI-ISCEPPPTISNGDFYSNN-RTSFHNGTVVTYQCHTGPDGEQL------FEL 1560
Query: 289 EEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
+ + +W S PPP + N V ++ R G + + + + I
Sbjct: 1561 VGERSIYCTSKDDQVGVWSS----PPPRCISTNKCTAPEV-ENAIRVPGNRSFFTLTEII 1615
Query: 349 DFKSR-GFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTV 404
F+ + GF + + + + S +C P E +G+ S +FS G V
Sbjct: 1616 RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEV 1675
Query: 405 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 458
+SC+ Y L+GA S+ C + WS P C VK+C L Q P G P
Sbjct: 1676 FYSCEPSYDLRGAASLHCTPQGD----WSPEAPRCTVKSCDDFLGQLPHGRVLLP 1726
Score = 65.9 bits (159), Expect = 7e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 590 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 629
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 969
Query: 630 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 685
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 970 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1014
Query: 686 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 736
T +V S + + H L A+ +SG + + P G+P
Sbjct: 1015 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1073
Query: 737 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 786
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 1074 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
Query: 787 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 844
C P C + +G+++S + SLN +PG +K LN
Sbjct: 1132 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 896
E+ + P +G P + S + ++ + G +H
Sbjct: 1188 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1247
Query: 897 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 950
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
Query: 951 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1358
Query: 1002 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1057
FN T D H NG ++ P R S F + I+
Sbjct: 1359 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
Query: 1058 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1092
DF S++YE F FS LE C P P G I
Sbjct: 1413 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
Query: 1093 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1150
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1532
Query: 1151 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1210
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1533 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 1582
Query: 1211 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1246
R + T N + + N E GF +V + +
Sbjct: 1583 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 1642
Query: 1247 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1300
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 1643 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 1700
Query: 1301 YPLPSCIAECGGRFKGE-SSGRILSP 1325
P C + F G+ GR+L P
Sbjct: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLP 1726
Score = 65.1 bits (157), Expect = 1e-09
Identities = 152/670 (22%), Positives = 244/670 (36%), Gaps = 117/670 (17%)
Query: 744 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 795
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
Query: 796 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 848
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
Query: 849 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 906
P++L + Q +F S Y L + R + T SC
Sbjct: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
Query: 907 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 961
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
Query: 962 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1019
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
Query: 1020 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1064
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
Query: 1065 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1105
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
Query: 1106 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1162
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
Query: 1163 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1213
+ + + G G + F L + D + I+ G + T ++
Sbjct: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
Query: 1214 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1257
L S + L+ +EF +G + V EL C P +
Sbjct: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
Query: 1258 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1316
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
Query: 1317 E-SSGRILSP 1325
+ +GR+L P
Sbjct: 814 QLLNGRVLFP 823
Score = 63.9 bits (154), Expect = 3e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
Query: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
C G T T+ +F ++TN+ NF + + Y
Sbjct: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
Query: 561 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
Query: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 676
S P VL + + +N + PG + S +DL G
Sbjct: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 677 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 726
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 727 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 764
E CP P + N R G + F G +++ C+
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
Query: 765 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 798
G TI C G +WS P+CG GH AP
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
Score = 60.8 bits (146), Expect = 2e-08
Identities = 136/619 (21%), Positives = 200/619 (32%), Gaps = 134/619 (21%)
Query: 584 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 635
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 692
G N C DP SF D ES + G+ S +P G +
Sbjct: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
Query: 693 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 731
P H T+ S L+++ GR F+IT + C
Sbjct: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
Query: 732 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 789
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
Query: 790 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 844
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 899
+ + GP + V L S + ++ L R GF + +
Sbjct: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
Query: 900 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 947
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 948 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
Query: 1006 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1065
L GS + AG+ + + +
Sbjct: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
Query: 1066 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1116
C P + G G F G + ++C + + L G S I
Sbjct: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
Query: 1117 ICLGG--GRRVWSAPLPRC 1133
C G VWS+P PRC
Sbjct: 919 RCTSDPQGNGVWSSPAPRC 937
Score = 60.1 bits (144), Expect = 4e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 705 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 753
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
Query: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 812
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
Query: 813 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 867
S+ PG + FE N D + + GP +P N P
Sbjct: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
Query: 868 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 910
L S + ++ L R GF + + +N + C P
Sbjct: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
Query: 911 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 967
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 968 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1025
G +G +L +P +L VD +G Q
Sbjct: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
Query: 1026 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1085
L GS + AG+ + + + C P +
Sbjct: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
Query: 1086 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1133
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 59.7 bits (143), Expect = 5e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 1078 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1134
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1135 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1184
CG T G +S N EN H + + + G G + F L
Sbjct: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
Query: 1185 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1239
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 1240 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1287
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
Query: 1288 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1346
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
Query: 1347 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1402
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
Query: 1403 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1456
G TV + CDP ++L
Sbjct: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
Query: 1457 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1512
GE I C + W P C G G +P+ F + D+
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
Query: 1513 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1559
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
Query: 1560 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1611
RI S T H L S +G + K R C P I NG +
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
Query: 1612 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1657
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 54.7 bits (130), Expect = 2e-06
Identities = 61/257 (23%), Positives = 92/257 (35%), Gaps = 50/257 (19%)
Query: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
FS +V+ F CQ GF + G + + CQ N+W +P C S P VL + +
Sbjct: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPDVLHAERTQ 760
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
+N + PG + S +DL GD SP +P + +
Sbjct: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
Query: 694 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 730
L N +L +++F D +G + +Y E C
Sbjct: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
Query: 731 PDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQGTETITCIL-MDGKVMWS 781
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 782 GLIPKCGAPCGGHFSAP 798
P+CG GH AP
Sbjct: 932 SPAPRCGIL--GHCQAP 946
Score = 51.2 bits (121), Expect = 2e-05
Identities = 184/870 (21%), Positives = 288/870 (33%), Gaps = 206/870 (23%)
Query: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 456
+ LG+ V F CDE + L+G+ + C +A + + W+ PVC+ C S P+G T
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCV-LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHT 883
Query: 457 SPN---FPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGD----GGEVGD 509
FPF N C FDL IG T+ G
Sbjct: 884 GKPLEVFPFGKAVNYTC----------DPHPDRGTSFDL-IGESTIRCTSDPQGNGVWSS 932
Query: 510 PRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY----------------- 552
P +L PD + L QT+ S +G + Y
Sbjct: 933 PAPRCGILGHCQAPDHFLFAK----LKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLD 988
Query: 553 -------KEI-EKESCGDPGTPLYG-IREGDGFSNRDVLRFECQFGFELIGEKSIVC--- 600
K++ +++SC P P+ G + + + C G LIG S C
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 601 QENNQWSANIPIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTII 648
WS PIC PC T G +S + Y G+ ++ ++
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 649 SDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 708
+P I+ + ND D + + G +P+ I
Sbjct: 1109 GEPS--IYCTSND-------DQVGIWSGPAPQCII------------------------- 1134
Query: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQG 765
N+C P + N DN F L + C+ GF+ +G
Sbjct: 1135 ------------------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKG 1174
Query: 766 TETITCILMDGKVMWSGLIPKCGAPC--------GGH-------FSAPSGVILS--PGWP 808
+ C ++ W +P C C G H FS V S PG+
Sbjct: 1175 PRRVKCQALN---KWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYD 1231
Query: 809 GYYKDSLNC----EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPL---LGSY 861
SL+C +W EA P ++K + + F +L + +L PL LG+
Sbjct: 1232 LRGAASLHCTPQGDWSPEA-PRCAVK-SCDDFLGQLPHG--------RVLFPLNLQLGAK 1281
Query: 862 NGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYG- 919
+ F S+ + + S NN + C +P ++GR G
Sbjct: 1282 VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPV------CEHIFCPNPPAILNGRHTGT 1335
Query: 920 --HDFSIGSTVSFSCD------SGYRLSHEEPLLCEK----NHWWSHPLPTCD-ALCGGD 966
D G +S++CD + L E + C N WS P P C+ ++ G
Sbjct: 1336 PSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGH 1395
Query: 967 VRGPSG-TILSPGYP--EF-YPNSLNCTWTVDVTH-GKGVQFN-FHTFHLEDHHDYLLIT 1020
+ P SP P +F +P + + + GK + D
Sbjct: 1396 CKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRK 1455
Query: 1021 ENGSFTQPLARL----TGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE---- 1072
G +P + T + T+N FR L + G N+T+ +
Sbjct: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFR--LIGSPSTTCLVSGNNVTWDKKAPI 1513
Query: 1073 YNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSCSSG------YRLEGTSEIICLGGGR 1123
+ CE P G N F G +T+ C +G + L G I C
Sbjct: 1514 CEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDD 1573
Query: 1124 R--VWSAPLPRCVAECGASATNNEGILLSP 1151
+ VWS+P PRC++ +A E + P
Sbjct: 1574 QVGVWSSPPPRCISTNKCTAPEVENAIRVP 1603
Score = 49.3 bits (116), Expect = 7e-05
Identities = 70/277 (25%), Positives = 100/277 (36%), Gaps = 34/277 (12%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNTAHWSTKPPICQ 1062
Query: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
G P + P+ ++VS + ++ + E GF
Sbjct: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
Query: 549 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 596
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 1177 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 597 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 631
S+ C WS P C +F P G VL P
Sbjct: 1237 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
Score = 48.1 bits (113), Expect = 2e-04
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 590 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 626
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 1360 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1419
Query: 627 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 679
T L+ + GY + N +W+ + D R K P
Sbjct: 1420 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1460
Query: 680 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 731
P G T + S + S + RL + G N+T++ C
Sbjct: 1461 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1520
Query: 732 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 782
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 1521 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 1580
Query: 783 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 837
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 1581 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 1640
Query: 838 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 895
+L + P +L L + Q +F S Y L +
Sbjct: 1641 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
Query: 896 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 950
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 1760
Query: 951 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1010
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 1761 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 1807
Query: 1011 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1054
+ + LI E NG ++ P R PP I G Y L
Sbjct: 1808 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 1866
Query: 1055 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1096
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 1867 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 1924
Query: 1097 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1135
GD +T C GY LEG+ C R W PL +C +
Sbjct: 1925 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 1967
Score = 47.0 bits (110), Expect = 3e-04
Identities = 68/277 (24%), Positives = 101/277 (36%), Gaps = 34/277 (12%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNAAHWSTKPPICQ 612
Query: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
G P + P+ ++VS + ++ + E GF
Sbjct: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 549 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 596
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
Query: 597 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 631
S+ C WS P C +F + G VL P
Sbjct: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
Score = 46.6 bits (109), Expect = 4e-04
Identities = 110/502 (21%), Positives = 165/502 (32%), Gaps = 160/502 (31%)
Query: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
Query: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
W P C +D G + G FP A + V + G
Sbjct: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 839
Query: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
FQ++ Y + G E ++W S + + PP+I N H
Sbjct: 840 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPN-----------GRH 882
Query: 334 RYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKR 393
+ + KA+++ P D F ++ E I+ S+ + R
Sbjct: 883 TGKPLEV-FPFGKAVNYTCD-----PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPR 936
Query: 394 IG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 431
G SDF +G+++++ C +Y + SITC
Sbjct: 937 CGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NLV 991
Query: 432 WSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFD 491
WS + VCK K+C + +G V VIT D
Sbjct: 992 WSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT---------------D 1020
Query: 492 LEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
+++ G + T L G + I+S ++ W T +
Sbjct: 1021 IQV---------GSRINYSCTTGHRLIGHSSAECILSGNTAHW---STKPPI-------- 1060
Query: 552 YKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKSI 598
++ CG P T I GD S NR+ V+ + C G FEL+GE SI
Sbjct: 1061 ---CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSI 1113
Query: 599 VCQENNQ----WSANIPICIFP 616
C N+ WS P CI P
Sbjct: 1114 YCTSNDDQVGIWSGPAPQCIIP 1135
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 1423 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1480
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 1481 IAPCGGNLTGSSGFILSPN 1499
PCG T ++G +S N
Sbjct: 163 RIPCGLPPTITNGDFISTN 181
Score = 44.7 bits (104), Expect = 0.002
Identities = 112/503 (22%), Positives = 165/503 (32%), Gaps = 162/503 (32%)
Query: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
Query: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
W P C +D G + G FP A + V + G
Sbjct: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 389
Query: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
FQ++ Y + G E ++W S + + PP+I N
Sbjct: 390 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPNG------------- 430
Query: 334 RYRGFSAPYQVKKAIDF-KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGK 392
R P +V F K+ + P D F ++ E I+ S+ +
Sbjct: 431 --RHTGKPLEV---FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 485
Query: 393 RIG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFA 430
R G SDF +G+++++ C +Y + SITC
Sbjct: 486 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NL 540
Query: 431 AWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEF 490
WS + VCK K+C + +G V VIT
Sbjct: 541 VWSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT--------------- 569
Query: 491 DLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
D+++ G + T L G + I+S ++ W T +
Sbjct: 570 DIQV---------GSRINYSCTTGHRLIGHSSAECILSGNAAHW---STKPPI------- 610
Query: 551 NYKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKS 597
++ CG P T I GD S NR+ V+ + C G FEL+GE S
Sbjct: 611 ----CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
Query: 598 IVCQENNQ----WSANIPICIFP 616
I C N+ WS P CI P
Sbjct: 663 IYCTSNDDQVGIWSGPAPQCIIP 685
Score = 41.6 bits (96), Expect = 0.014
Identities = 57/260 (21%), Positives = 99/260 (38%), Gaps = 43/260 (16%)
Query: 194 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 252
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 1416 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1469
Query: 253 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 310
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 1470 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1522
Query: 311 NIPPPIISNKNWLRLHFVTDSNHR---YRGFSAPYQVKKAID----FKSRGFKLFPGKDN 363
P ISN ++ SN+R + G YQ D F+ G +
Sbjct: 1523 ----PTISNGDFY-------SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
Query: 364 SNKFSILNEGGIKTAS-NLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKS 419
++ + + + S N C P E EN R+ + F+L ++F C +V+ G+ +
Sbjct: 1572 DDQVGVWSSPPPRCISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 1630
Query: 420 ITCQRIAEVFAAWSDHRPVC 439
+ CQ W P C
Sbjct: 1631 VQCQ----TNGRWGPKLPHC 1646
Score = 37.0 bits (84), Expect = 0.35
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 382 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 438
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 1903
Query: 439 CKVKTC 444
CK C
Sbjct: 1904 CKEVNC 1909
Score = 33.9 bits (76), Expect = 2.9
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 1728 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 1774
Score = 33.5 bits (75), Expect = 3.8
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 1964 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2011
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 1973
Score = 32.7 bits (73), Expect = 6.5
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 225 TASWDFPVPICRAEDAC 241
W P P C + C
Sbjct: 672 VGIWSGPAPQCIIPNKC 688
Score = 32.7 bits (73), Expect = 6.5
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1121
Query: 225 TASWDFPVPICRAEDAC 241
W P P C + C
Sbjct: 1122 VGIWSGPAPQCIIPNKC 1138
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 397 bits (1020), Expect = e-109
Identities = 475/1883 (25%), Positives = 692/1883 (36%), Gaps = 356/1883 (18%)
Query: 1594 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
Query: 1653 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1707
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 1708 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1762
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
Query: 1763 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1812
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
Query: 1813 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1871
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
Query: 1872 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 1931
++ S+ +SL + S + V
Sbjct: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
Query: 1932 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 1982
F CP P +G G + + G V++ CD + L G
Sbjct: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
Query: 1983 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
S I C P W+ P P C G++ P
Sbjct: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
Query: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2100
H F T+T + T + P+ FS T +L + S
Sbjct: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
Query: 2101 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2159
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
Query: 2160 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2217
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
Query: 2218 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2264
F ++ IY D + +W GP P + + S++S +
Sbjct: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
Query: 2265 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2314
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
Query: 2315 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2374
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
Query: 2375 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
Query: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2488
+ +C +P P+G TG L V
Sbjct: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKTV 896
Query: 2489 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2533
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
Query: 2534 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGEL 2593
TN +D+ +GT + Y C Y +T C + WS+ C SC
Sbjct: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
Query: 2594 PTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCG 2649
P P NG + T GS ++C G L+G + EC+ SG WS C CG
Sbjct: 1008 PDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCG 1067
Query: 2650 IPELIVNGQVIG---ENYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSG 2696
+P I NG I EN+ Y V Y+CNPG F L+G C + + WSG
Sbjct: 1068 LPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSG 1127
Query: 2697 QLPSC-VPVSCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWS 2753
P C +P C P + I + + F+ N+VV F C G++M+GP + +CQA +W
Sbjct: 1128 PAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
Query: 2754 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ 2813
P C V C P +++R + + NF+ G VFY C PGY L G++ + C P G
Sbjct: 1188 PELPSCSRV-CQPPPDVLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD 1245
Query: 2814 WDKPLPECIMIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 2871
W P C + C + VL G+ V + C L G S+ C L G
Sbjct: 1246 WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGM 1305
Query: 2872 ---WSGSQPHCSGDATGTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILH 2920
W+ S P C + P P H + F V Y CD T + L
Sbjct: 1306 ESLWNSSVPVC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI 1363
Query: 2921 GSEERTCLA----NGSWTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSS 2967
G C + NG W+ P C + C P T N F I +S
Sbjct: 1364 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTS 1418
Query: 2968 VIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNV 3026
+ Y C Y P C N WS C SC P P NG+ + D VG +
Sbjct: 1419 LKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 1477
Query: 3027 SYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NF 3080
+Y C G+ L G C ++G WS P C+ + C PP I+NG T NF
Sbjct: 1478 NYSCTTGH--RLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENF 1535
Query: 3081 DWGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP---- 3125
+G ++Y C+ G +EL + C N G WSG PQC +P C P
Sbjct: 1536 HYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 1595
Query: 3126 GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCEN 3185
GI R F V F C F++ G CQA W P C C+
Sbjct: 1596 GILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQP 1649
Query: 3186 PGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCK 3243
P HG + ++ F G V + C+ G+ L+G+ + C P WS P C SC
Sbjct: 1650 PPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCD 1709
Query: 3244 Q--PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICEA 3299
+ P H V+ G + + C GF L G + + + W VP+CE
Sbjct: 1710 DFLGQLP-HGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCE- 1767
Query: 3300 GSKILVKDPRPAL------GTPS 3316
I +P PA+ GTPS
Sbjct: 1768 --HIFCPNP-PAILNGRHTGTPS 1787
Score = 354 bits (909), Expect = 8e-97
Identities = 387/1478 (26%), Positives = 562/1478 (38%), Gaps = 230/1478 (15%)
Query: 1966 VGDVVSFQCDQGYSLQGHSHITC-MPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFP 2024
+G V F CD+G+ L+G S C + G WN +P+ C VI +
Sbjct: 828 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV----CEQIFCPSPPVIPNGRHT 883
Query: 2025 GN----YPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE---VRSGSSETSTVIGRL 2077
G +P +T + G + ST + V S + ++G
Sbjct: 884 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 943
Query: 2078 SGPQ--IPSSLFSTTHE------TSLYFHSDYSQNKQGFHIVY----------QAYQLQS 2119
P + + L + T+ TSL + + F I + +S
Sbjct: 944 QAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKS 1003
Query: 2120 CPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRCEA 2177
C P NG V + D VG I++ C G+ LIG+S+ C L G + +W+ P C+
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 1063
Query: 2178 L-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----D 2231
+ CG T NG S + + + R PG+G F ++ IY D
Sbjct: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGGRKVFELVGEPSIYCTSNDD 1120
Query: 2232 FITVWDGPDQNS--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSY 2283
+ +W GP P + + S++S + + + F G +
Sbjct: 1121 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
Query: 2284 HAYQL---------RVCQPPPPVPNAEILTED-DEFEIGDIIRYQCLPGFTLVGNAILTC 2333
A RVCQPPP V +AE D D F G + Y C PG+ L G A + C
Sbjct: 1181 QALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 1240
Query: 2334 RLGERLQMDGAP--PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYN 2391
Q D +P P C+V + + G +L P ++++ G
Sbjct: 1241 TP----QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP---------------VNLQLGAK 1281
Query: 2392 ITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN 2451
+ F ++ F + G + VL + ++S+ +
Sbjct: 1282 VD-----FVCDEGFQL----KGSSASYCVLAGMESLWNSSVPVCEQ-------------- 1318
Query: 2452 NKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLN-----SVVRWACD----RG--FRLVG 2500
+C +P P+G TG L V + CD RG F L+G
Sbjct: 1319 -----------IFCPSPPVIPNG---RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIG 1364
Query: 2501 KSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KAPTNGGILTTDYLVGTRVT 2551
+S+ C G W +P P C + C P K TN +D+ +GT +
Sbjct: 1365 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA----SDFPIGTSLK 1420
Query: 2552 YFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGN-KIGTQTSYGS 2610
Y C Y +T C + WS+ C SC P P NG + T GS
Sbjct: 1421 YECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTPPDPVNGMVHVITDIQVGS 1475
Query: 2611 TAIFTCDLGFMLVGSAVRECLSSGL---WSESETRCLAGHCGIPELIVNGQVIG---ENY 2664
++C G L+G + EC+ SG WS C CG+P I NG I EN+
Sbjct: 1476 RINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENF 1535
Query: 2665 GYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PVSCGHPG--S 2711
Y V Y+CN G F L+G C + + WSG P C+ P C P +
Sbjct: 1536 HYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 1595
Query: 2712 PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2771
I + + F+ N+VV F C G++M+GP + +CQA +W P C V P I
Sbjct: 1596 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILH 1655
Query: 2772 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH--P 2829
S NF+ G VFY C PGY L G++ L C P G W P C + C
Sbjct: 1656 GEHTPS--HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLG 1713
Query: 2830 GVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGT 2886
+P VL G+ V + C L G S C L G W+ S P C
Sbjct: 1714 QLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI---F 1770
Query: 2887 CGDPG---TPGHGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA----NGSW 2933
C +P H + + Y CD + L G C + NG W
Sbjct: 1771 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVW 1830
Query: 2934 TGRQPECK-AVQCGNPGTTAN----GKVFRIDGTTF--SSSVIYSCMEGYILSGPSVRQC 2986
+ P C+ +V+ G+ T I+ F +S+ Y C GY S+ C
Sbjct: 1831 SSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SC 1889
Query: 2987 TANGTWSGTLPNCTIISCGDPGIPANGL-RYGDDYVVGQNVSYMCQPGYTMELNGSRIRT 3045
N WS NC SCG P P NG+ D G V+Y C G+ L GS T
Sbjct: 1890 LENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGF--RLIGSPSTT 1947
Query: 3046 CTING---TWSGVMPTCRAVTCPTPPQISNGRL---EGTNFDWGFSISYICSPG------ 3093
C ++G TW P C ++C PP ISNG T+F G ++Y C G
Sbjct: 1948 CLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL 2007
Query: 3094 YELSFPAVLTCVGN----GTWSGEVPQCL-PKFCGDPGIPAQGKREG-KSFIYQSE-VSF 3146
+EL + C G WS P+C+ C P + + G +SF +E + F
Sbjct: 2008 FELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRF 2067
Query: 3147 SCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGS 3204
C F++VGS T CQ +G W PHC C+ P HG ++ F G
Sbjct: 2068 RCQPGFVMVGSHTVQCQTNGRWGPKLPHC----SRVCQPPPEILHGEHTLSHQDNFSPGQ 2123
Query: 3205 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ--PETPAHANVVGMDLPSHG 3262
V + C+ + L+G+ + C P WS P C SC + P ++ ++L G
Sbjct: 2124 EVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNL-QLG 2182
Query: 3263 YTLIYTCQPGFFLAG-GTEHRVCRSDNT-WTGKVPICE 3298
+ + C GF L G H V W VP+CE
Sbjct: 2183 AKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 2220
Score = 306 bits (785), Expect = 2e-82
Identities = 268/919 (29%), Positives = 382/919 (41%), Gaps = 110/919 (11%)
Query: 2465 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2520
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
Query: 2521 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2578
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
Query: 2579 HNKTPRCVVISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRE 2629
N+TP C I CG PT NG+ I T YGS + C+ G F LVG
Sbjct: 156 -NETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIY 214
Query: 2630 CLSS----GLWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIG 2682
C S+ G+WS +C+ + P + NG ++ +N + + V ++C PGF + G
Sbjct: 215 CTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKG 274
Query: 2683 SSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG-RTSGNGFNFN--DVVTFSCNIGYLMQ 2739
CQ + W +LPSC V C P ++ RT + NF+ V +SC GY ++
Sbjct: 275 PRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 333
Query: 2740 GPTKAQCQANRQWSHPPPMCKVVNCSD-PGIPANSKRESKIEHGNFTYGTVVFYDCNPGY 2798
G +C WS P C+V +C D G N + + N G V + C+ G+
Sbjct: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPV---NLQLGAKVDFVCDEGF 390
Query: 2799 FLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSC 2852
L GSS C G W+ +P C I C P V PN +G E + FG TV+Y+C
Sbjct: 391 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC 450
Query: 2853 T------GKRSLLGQSSRTC----QLNGHWSGSQPHCSGDATGTCGDPGTPGH------- 2895
L+G+S+ C Q NG WS P C G G P H
Sbjct: 451 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLK 505
Query: 2896 GSRQESNFRTKSTVRYACDTGYILHGSE-ERTCLANGSWTGRQPECKAVQCGNPGTTANG 2954
S+F ++++Y C Y +G TCL N W+ + CK C P NG
Sbjct: 506 TQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNG 563
Query: 2955 KVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPA 3011
V I S + YSC G+ L G S +C +G WS P C I CG P A
Sbjct: 564 MVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIA 623
Query: 3012 NG---LRYGDDYVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCR 3060
NG +++ G V+Y C PG EL G CT N G WSG P C
Sbjct: 624 NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 683
Query: 3061 AVTCPTPPQISNGRLEGTN---FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117
TPP + NG L N F + + C PG+ + P + C W E+P C
Sbjct: 684 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 743
Query: 3118 LPKFCGDPG---IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPH 3174
+ C P + +R+ +F EV +SC + L G+++ C G WS ++P
Sbjct: 744 -SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT 802
Query: 3175 CIEPTQTSCEN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTW 3230
C SC++ G +G Q+G+ V F C +G L+GS+ C+ + W
Sbjct: 803 C---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLW 859
Query: 3231 SGIQPECIPHSCKQPETPAHANVVG--MDLPSHGYTLIYTCQP------GFFLAGGTEHR 3282
+ P C C P + G +++ G T+ YTC P F L G + R
Sbjct: 860 NSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIR 919
Query: 3283 VCRSD----NTWTGKVPIC 3297
C SD W+ P C
Sbjct: 920 -CTSDPQGNGVWSSPAPRC 937
Score = 291 bits (744), Expect = 1e-77
Identities = 240/829 (28%), Positives = 335/829 (40%), Gaps = 96/829 (11%)
Query: 2543 DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGN-K 2601
++ +GT + Y C GY S + +C + W+ RC SC P P NG
Sbjct: 62 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWTGAKD--RCRRKSCRNPPDPVNGMVH 116
Query: 2602 IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQ 2658
+ +GS ++C G+ L+GS+ C+ SG +W C CG+P I NG
Sbjct: 117 VIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGD 176
Query: 2659 VIG---ENYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PV 2704
I EN+ Y V Y+CNPG F L+G C + + WSG P C+ P
Sbjct: 177 FISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN 236
Query: 2705 SCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2762
C P + I + + F+ N+VV F C G++M+GP + +CQA +W P C V
Sbjct: 237 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
Query: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
C P +++R + + NF+ G VFY C PGY L G++ + C P G W P C
Sbjct: 297 -CQPPPDVLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE 354
Query: 2823 MIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQP 2877
+ C + VL G+ V + C L G S+ C L G W+ S P
Sbjct: 355 VKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 414
Query: 2878 HCSGDATGTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA 2929
C + P P H + F TV Y CD T + L G C +
Sbjct: 415 VC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTS 472
Query: 2930 ----NGSWTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGY 2976
NG W+ P C + C P T N F I +S+ Y C Y
Sbjct: 473 DPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY 527
Query: 2977 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYT 3035
P C N WS C SC P P NG+ + D VG ++Y C G+
Sbjct: 528 -YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH- 585
Query: 3036 MELNGSRIRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYI 3089
L G C ++G WS P C+ + C PP I+NG T NF +G ++Y
Sbjct: 586 -RLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYR 644
Query: 3090 CSPG------YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKRE 3134
C+PG +EL + C N G WSG PQC +P C P GI R
Sbjct: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR- 703
Query: 3135 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG-- 3192
F V F C F++ G CQA W P C C+ P H
Sbjct: 704 -SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAER 758
Query: 3193 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHA 3251
+Q + F G V + C+ G+ L+G+ + C P WS P C SC +
Sbjct: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 818
Query: 3252 NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3298
V+ G + + C GF L G + + ++ W VP+CE
Sbjct: 819 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
Score = 288 bits (736), Expect = 9e-77
Identities = 448/1942 (23%), Positives = 694/1942 (35%), Gaps = 374/1942 (19%)
Query: 1270 GSTIIYGCNPG------YTLHGSSLLKCMTGERRA--WDYPLPSCIAECGGRFKGESSGR 1321
GS + Y CNPG + L G + C + + + W P P CI +G
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 697
Query: 1322 ILSPGYPFPYDNNL---RCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLL 1378
++S N + RC + V Q L RV PP+
Sbjct: 698 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPD----- 752
Query: 1379 KEISGSLIPEGIHSTLNIVTIQFDTD--------FYISKSGFAIQFSSSVATACR---DP 1427
L+ Q D D FY + G+ ++ ++S+ + P
Sbjct: 753 --------------VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 798
Query: 1428 GVPMNGTRNGD--------GR-------EPGDTVVFQCDPGYELQGEERITCIQVENRYF 1472
P ++ D GR + G V F CD G++L+G C+
Sbjct: 799 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 858
Query: 1473 WQPSPPVCIAPCGGNLTGSSGFILSPNFPHP------YPHSRDCDWTITVNADYVISLAF 1526
W S PVC + S ++ PN H +P + ++T + D S
Sbjct: 859 WNSSVPVC-----EQIFCPSPPVI-PNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 912
Query: 1527 ISFSI-----EPNYDFLYIYDGPDSNSPLIGSFQD------SKLPERIESSSNTMHLAFR 1575
I S +P + ++ P ++G Q +KL + +S + + +
Sbjct: 913 IGESTIRCTSDPQGNG--VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK 970
Query: 1576 SDGSVSYTG--FHLEYKAKL----------RESCFDPGNIMNG-TRLGMDYKLGSTVTYY 1622
+ Y G F + L R+SC P + +NG + D ++GS + Y
Sbjct: 971 YECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYS 1030
Query: 1623 CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVG 1681
C G+ L G+S+ CI+ + W+ P C PCG T + G +S N +N+ G
Sbjct: 1031 CTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPPTIANGDFISTNR-ENFHYG 1088
Query: 1682 ----HNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLP 1737
+ C K F + G+ + TS D V ++ GP Q + + + + +
Sbjct: 1089 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1148
Query: 1738 LSSGNQI-----TIRFTSVGPITAKGFHFVY-QAVPRTSST--QCSSVPEP-------RF 1782
+S + + F KG V QA+ + CS V +P
Sbjct: 1149 VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAER 1208
Query: 1783 GRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTK 1841
+R + F+ G V + C PGY L G+ ++RC W+ + PTC + C +
Sbjct: 1209 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC----TPQGDWSPAAPTCEVKSCDDFM-- 1262
Query: 1842 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1901
G +L+ P + L EG ++ S+ +SL
Sbjct: 1263 --GQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL------------ 1308
Query: 1902 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 1961
+ S + V F CP P +G G
Sbjct: 1309 -----------------------WNSSVPVCEQIF-----------CPSPPVIPNGRHTG 1334
Query: 1962 ---DRYMVGDVVSFQCDQ------GYSLQGHSHITCMPGPVRR--WNYPIPICLAQCGGA 2010
+ + G V++ CD + L G S I C P W+ P P C
Sbjct: 1335 KPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC------- 1387
Query: 2011 MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSET 2070
G++ P H F T+T +
Sbjct: 1388 -----GILGHCQAPD--------------------HFLFAKLKTQT-------NASDFPI 1415
Query: 2071 STVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGF 2130
T + P+ FS T +L + S K+ +SC P NG
Sbjct: 1416 GTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKR-----------KSCKTPPDPVNGM 1464
Query: 2131 V-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRCEAL-CGGNITAMN 2187
V + D VG I++ C G+ LIG+S+ C L G + +W+ P C+ + CG T N
Sbjct: 1465 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIAN 1524
Query: 2188 GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----DFITVWDGPDQN 2242
G S + + + G + F ++ IY D + +W GP
Sbjct: 1525 GDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVGEPSIYCTSNDDQVGIWSGPAPQ 1581
Query: 2243 S--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQL------ 2288
P + + S++S + + + F G + A
Sbjct: 1582 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 1641
Query: 2289 ---RVCQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA 2344
RVCQPPP + + E + D F G + Y C PG+ L G A L C Q D +
Sbjct: 1642 SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP----QGDWS 1697
Query: 2345 P--PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISV------EKGYNITMFV 2396
P P C V + L G +L P NLQ+ A V KG +++ V
Sbjct: 1698 PEAPRCAVKSCDDFLGQLPHGRVLFP------LNLQLGAKVSFVCDEGFRLKGSSVSHCV 1751
Query: 2397 EFFQTEKEFDVLQVYDGPNIQSPVLI-------SLSGD--YSSAFNITSNGH-------- 2439
+ + V + +P I + SGD Y + T + H
Sbjct: 1752 LVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFN 1811
Query: 2440 ---EVFLQWSAD-HGNN-----KKGFRIRYIAFYCSTPESPPHG---YIISQTGGQLNSV 2487
E ++ ++D HGN + A +C TPE P I+ + +
Sbjct: 1812 LIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTS 1871
Query: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI-LTTDYLV 2546
+ + C G+ GK ++ S W + C+ SCG P P NG + + TD
Sbjct: 1872 LNYECRPGY--FGKMFSI---SCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF 1926
Query: 2547 GTRVTYFCNDGYRLSSKELTTAVCQSDG-TWSNHNKTPRCVVISCGELPTPPNGNKIGT- 2604
G+ V Y CN+G+RL TT + + TW K P C +ISC PT NG+
Sbjct: 1927 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDK--KAPICEIISCEPPPTISNGDFYSNN 1984
Query: 2605 QTSY--GSTAIFTCDLG------FMLVGSAVRECLSS----GLWSESETRCLAGH-CGIP 2651
+TS+ G+ + C G F LVG C S G+WS RC++ + C P
Sbjct: 1985 RTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAP 2044
Query: 2652 ELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP 2709
E+ +V G + + + ++C PGF ++GS CQ + W +LP C V C P
Sbjct: 2045 EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPP 2103
Query: 2710 GSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSD 2766
++G + + F+ V +SC Y ++G C WS P C V +C D
Sbjct: 2104 PEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDD 2163
Query: 2767 PGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ---WDKP 2817
++ HG N G V + C+ G+ L G S C G W+
Sbjct: 2164 --------FLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSS 2215
Query: 2818 LPECIMIDCGHPGVPPNAVLSGEKY---TFGSTVHYSCTGKR------SLLGQSSRTC-- 2866
+P C I C +P N +G + +G + Y+C +L+G+SS C
Sbjct: 2216 VPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTS 2275
Query: 2867 --QLNGHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHG 2921
Q NG WS P C C P +G S + T+ Y CD GY+L G
Sbjct: 2276 DPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVG 2335
Query: 2922 SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT---FSSSVIYSCMEGYIL 2978
C G W+ CK V C P NG ++ + V C +GY L
Sbjct: 2336 KGFIFCTDQGIWSQLDHYCKEVNCSFP-LFMNGISKELEMKKVYHYGDYVTLKCEDGYTL 2394
Query: 2979 SGPSVRQCTANGTWSGTLPNCT 3000
G QC A+ W L CT
Sbjct: 2395 EGSPWSQCQADDRWDPPLAKCT 2416
Score = 278 bits (711), Expect = 7e-74
Identities = 243/858 (28%), Positives = 342/858 (39%), Gaps = 118/858 (13%)
Query: 2467 TPESPPHGYIISQTGG--QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
TP + +G ++S LN VV + C GF + G C+ + W+ +P+C
Sbjct: 1589 TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ----ALNKWEPELPSCS 1644
Query: 2525 AISCGIPKAPTNGGILTT---DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
+ C P +G + ++ G V Y C GY L + + C G WS +
Sbjct: 1645 RV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDL--RGAASLHCTPQGDWSP--E 1699
Query: 2582 TPRCVVISCGE-LPTPPNGNKI-GTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LW 2636
PRC V SC + L P+G + G+ F CD GF L GS+V C+ G LW
Sbjct: 1700 APRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLW 1759
Query: 2637 SESETRCLAGHCGIPELIVNGQVIGENYG---YRDTVVYQCNPG------FRLIGSSVRI 2687
+ S C C P I+NG+ G G Y + Y C+P F LIG S
Sbjct: 1760 NNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIR 1819
Query: 2688 CQQDHN----WSGQLPSC-VPVSCGHPGSPIYGRTSGNGFNFNDV-------VTFSCNIG 2735
C D + WS P C + V GH +P + ND + + C G
Sbjct: 1820 CTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPG 1879
Query: 2736 YLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2795
Y + C N WS C+ +C P P N + +G+ V Y CN
Sbjct: 1880 YFGK-MFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDT---QFGSTVNYSCN 1935
Query: 2796 PGYFLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGEKYTF-------G 2845
G+ L GS C +G WDK P C +I C PP + +G+ Y+ G
Sbjct: 1936 EGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE----PPPTISNGDFYSNNRTSFHNG 1991
Query: 2846 STVHYSC-TGKRS-----LLGQSSRTCQLN----GHWSGSQPHCSGDATGTCGDPGT--- 2892
+ V Y C TG L+G+ S C G WS P C +T C P
Sbjct: 1992 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCI--STNKCTAPEVENA 2049
Query: 2893 ---PGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG 2949
PG+ S F +R+ C G+++ GS C NG W + P C V C P
Sbjct: 2050 IRVPGN----RSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPP 2104
Query: 2950 TTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGD- 3006
+G+ FS V YSC Y L G + CT G WS P CT+ SC D
Sbjct: 2105 EILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF 2164
Query: 3007 -PGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAV 3062
+P + + +G VS++C G+ L G C + G W+ +P C +
Sbjct: 2165 LGQLPHGRVLLPLNLQLGAKVSFVCDEGF--RLKGRSASHCVLAGMKALWNSSVPVCEQI 2222
Query: 3063 TCPTPPQISNGRLEGTNF---DWGFSISYICS--PGYELSFPAV----LTCV----GNGT 3109
CP PP I NGR GT F +G ISY C P ++F + + C GNG
Sbjct: 2223 FCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGV 2282
Query: 3110 WSGEVPQC---LPKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQ 3163
WS P+C +P C P G G ++ +S+ C+ ++LVG C
Sbjct: 2283 WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCT 2342
Query: 3164 ADGTWSGSSPHCIEPTQTSCENP----GVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGS 3219
G WS +C E +C P G+ + + + G V C+ G+ L+GS
Sbjct: 2343 DQGIWSQLDHYCKE---VNCSFPLFMNGISKELEMKKVYHY--GDYVTLKCEDGYTLEGS 2397
Query: 3220 TTRTCLPDLTWSGIQPEC 3237
C D W +C
Sbjct: 2398 PWSQCQADDRWDPPLAKC 2415
Score = 270 bits (689), Expect = 2e-71
Identities = 242/925 (26%), Positives = 370/925 (40%), Gaps = 117/925 (12%)
Query: 2465 CSTPESPPHGYIISQTGGQLN--SVVRWACDRG------FRLVGKSSAVCRKSSYGYHAW 2516
C P + +G IS + SVV + C+ G F LVG+ S C + W
Sbjct: 1516 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1575
Query: 2517 DAPVPACQAISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQS 2572
P P C + P NG IL +D + + V + C G+ + CQ+
Sbjct: 1576 SGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK--CQA 1632
Query: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDLGFMLVGS 2625
W + SC + PP G T S G ++C+ G+ L G+
Sbjct: 1633 LNKWEPE-------LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1685
Query: 2626 AVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS 2683
A C G WS RC C + +L + N V + C+ GFRL GS
Sbjct: 1686 ASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGS 1745
Query: 2684 SVRICQ---QDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN---GFNFNDVVTFSCN---- 2733
SV C W+ +P C + C +P + + GR +G + ++++C+
Sbjct: 1746 SVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPD 1805
Query: 2734 --IGYLMQGPTKAQCQA----NRQWSHPPPMCKVV----NCSDPGIPANSKRESKIEHGN 2783
+ + + G + +C + N WS P P C++ +C P + I
Sbjct: 1806 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFE 1865
Query: 2784 FTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 2841
F GT + Y+C PGYF +F S C N W C CG P P N ++
Sbjct: 1866 FPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1922
Query: 2842 YT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPGTPGHG- 2896
T FGSTV+YSC L+G S TC ++G+ W P C +C P T +G
Sbjct: 1923 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPPPTISNGD 1979
Query: 2897 --SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECKAV- 2943
S ++F + V Y C TG + L G C + G W+ P C +
Sbjct: 1980 FYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTN 2039
Query: 2944 QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2999
+C P R+ G T + + + C G+++ G QC NG W LP+C
Sbjct: 2040 KCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 2096
Query: 3000 TIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3057
+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G WS P
Sbjct: 2097 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQGDWSPEAP 2154
Query: 3058 TCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSG 3112
C +C Q+ +GR L N G +S++C G+ L + CV G W+
Sbjct: 2155 RCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNS 2214
Query: 3113 EVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVGSSTRICQ 3163
VP C FC +P G+ G F Y E+S++C+ F L+G S+ C
Sbjct: 2215 SVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCT 2274
Query: 3164 AD----GTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQ 3217
+D G WS +P C +C +P ++G + + G + + C G+LL
Sbjct: 2275 SDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLV 2334
Query: 3218 GSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTLIYTCQPG 3272
G C WS + C +C P N + +L +G + C+ G
Sbjct: 2335 GKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYVTLKCEDG 2391
Query: 3273 FFLAGGTEHRVCRSDNTWTGKVPIC 3297
+ L G + C++D+ W + C
Sbjct: 2392 YTLEGSPWSQ-CQADDRWDPPLAKC 2415
Score = 80.1 bits (196), Expect = 4e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 1907 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1965
Query: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 1966 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 2000
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 2001 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 2050
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 620
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 2051 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 2098
Query: 621 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 678
P +L ++ + +N + PG + S +DL GD S
Sbjct: 2099 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 2150
Query: 679 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 738
PE+P + + L +L L
Sbjct: 2151 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 2177
Query: 739 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 2178 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 2219
Score = 72.4 bits (176), Expect = 7e-12
Identities = 225/1043 (21%), Positives = 355/1043 (34%), Gaps = 219/1043 (20%)
Query: 744 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 795
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
Query: 796 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 848
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
Query: 849 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 906
P++L + Q +F S Y L + R + T SC
Sbjct: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
Query: 907 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 961
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
Query: 962 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1019
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
Query: 1020 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1064
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
Query: 1065 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1105
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
Query: 1106 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1162
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
Query: 1163 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1213
+ + + G G + F L + D + I+ G + T ++
Sbjct: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
Query: 1214 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1257
L S + L+ +EF +G + V EL C P +
Sbjct: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
Query: 1258 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1316
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
Query: 1317 E-SSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDIL----RVWDGP 1371
+ +GR+L FP + L D G F + AS+ +L +W+
Sbjct: 814 QLLNGRVL-----FPVNLQLGAKVDFVCDEG------FQLKGSSASYCVLAGMESLWNSS 862
Query: 1372 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
+ S +IP G H+ + F
Sbjct: 863 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPF------------------------------ 892
Query: 1432 NGTRNGDGREPGDTVVFQCDP------GYELQGEERITCI-QVENRYFWQPSPPVCIAPC 1484
G TV + CDP ++L GE I C + W P C
Sbjct: 893 -----------GKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---- 937
Query: 1485 GGNLTGSSGFILSPN---FPHPYPHSRDCDWTITVNADYVISLAFIS--FSIEPNYDFLY 1539
G G +P+ F + D+ I + Y + FSI + ++
Sbjct: 938 -----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVW 992
Query: 1540 -----------IYDGPDSNSPLIGSFQDSKLPERIESSSNTMH-LAFRSDGSVSYTGFHL 1587
PD + ++ D ++ RI S T H L S +G
Sbjct: 993 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAA 1052
Query: 1588 EYKAK----LRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYST 1634
+ K R C P I NG + ++ GS VTY C+ G + L G +
Sbjct: 1053 HWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 1112
Query: 1635 LTCIMGDDGRPGWNRALPSCHAP 1657
+ C DD W+ P C P
Sbjct: 1113 IYCTSNDDQVGIWSGPAPQCIIP 1135
Score = 71.2 bits (173), Expect = 2e-11
Identities = 82/293 (27%), Positives = 123/293 (41%), Gaps = 33/293 (11%)
Query: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
SC P P G+++ T VG +I YSC TG+ L GH CI S NTA W PIC
Sbjct: 1453 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSTKPPIC 1511
Query: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYL 295
+ CG ++G S + N ++ + + G + F++ +
Sbjct: 1512 Q-RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV------FELVGEPSIY 1564
Query: 296 EIEGSEPPTIWLSGMNIPPPIISNK----NWLRLHFVTDSNHRYRGFSAPYQVKKAIDFK 351
+ IW SG P II NK N V+D+ + + + + ++F+
Sbjct: 1565 CTSNDDQVGIW-SG-PAPQCIIPNKCTPPNVENGILVSDNR-------SLFSLNEVVEFR 1615
Query: 352 SRGFKLFPGKDNSNKFSILN--EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQF 406
+ + G K LN E + + S +C P E +G+ S +FS G V +
Sbjct: 1616 CQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFY 1674
Query: 407 SCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 458
SC+ Y L+GA S+ C + WS P C VK+C L Q P G P
Sbjct: 1675 SCEPGYDLRGAASLHCTPQGD----WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1723
Score = 70.9 bits (172), Expect = 2e-11
Identities = 196/861 (22%), Positives = 310/861 (36%), Gaps = 172/861 (19%)
Query: 590 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 629
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 460 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 519
Query: 630 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 685
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 520 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 564
Query: 686 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 736
T +V S + + H L A+ +SG + + P G+P
Sbjct: 565 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPC-GLPPTIA 623
Query: 737 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 786
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 624 NGDFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
Query: 787 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQ 837
C P C + +G+++S + SLN +PG +K +++
Sbjct: 682 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 737
Query: 838 TELNYDVLEVHDGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 895
EL P++L + Q +F S Y L + R
Sbjct: 738 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
Query: 896 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNH 950
+ T SC D G ++GR + + +G+ V F CD G++L C
Sbjct: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES 857
Query: 951 WWSHPLPTCDAL-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTF 1008
W+ +P C+ + C P+G G P E +P +T D +G F+
Sbjct: 858 LWNSSVPVCEQIFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD---- 911
Query: 1009 HLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SD 1058
LI E+ + G P G+ G+ +A F+ SD
Sbjct: 912 ---------LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 962
Query: 1059 F----SISYE--------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNF 1094
F S+ YE F+IT + NL + C+ P P G + +
Sbjct: 963 FPIGTSLKYECRPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDI 1021
Query: 1095 GIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPN 1152
+G + +SC++G+RL G S C L G WS P C CG T G +S N
Sbjct: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
Query: 1153 YPLNYENNHE-CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHL 1202
EN H + + + G G + F L + D + I+ G +
Sbjct: 1082 R----ENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII 1134
Query: 1203 LGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE 1251
T ++ L S + L+ +EF +G + V EL C
Sbjct: 1135 PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCS 1194
Query: 1252 -----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPS 1305
P + D+ +F+ G + Y C PGY L G++ ++C + W P+
Sbjct: 1195 RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPT 1252
Query: 1306 CIAECGGRFKGE-SSGRILSP 1325
C + F G+ +GR+L P
Sbjct: 1253 CEVKSCDDFMGQLLNGRVLFP 1273
Score = 70.5 bits (171), Expect = 3e-11
Identities = 75/279 (26%), Positives = 116/279 (41%), Gaps = 34/279 (12%)
Query: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
Query: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 290
+ CG ++G S + N +H + T+ PG +F
Sbjct: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
Query: 291 KYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
D + I P + PP + +N + V+D+ + + + + ++F
Sbjct: 668 NDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSLNEVVEF 714
Query: 351 KSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQ 405
+ + + G K LN E + + S +C PD E +R +FS G V
Sbjct: 715 RCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVF 773
Query: 406 FSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
+SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 774 YSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 808
Score = 70.5 bits (171), Expect = 3e-11
Identities = 75/279 (26%), Positives = 116/279 (41%), Gaps = 34/279 (12%)
Query: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 1061
Query: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 290
+ CG ++G S + N +H + T+ PG +F
Sbjct: 1062 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 1117
Query: 291 KYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
D + I P + PP + +N + V+D+ + + + + ++F
Sbjct: 1118 NDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSLNEVVEF 1164
Query: 351 KSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQ 405
+ + + G K LN E + + S +C PD E +R +FS G V
Sbjct: 1165 RCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVF 1223
Query: 406 FSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
+SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 1224 YSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 1258
Score = 69.7 bits (169), Expect = 5e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 1606 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1660
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
+ +N + PG + S +DL GD SPE+P
Sbjct: 1661 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1701
Query: 694 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 753
R ++ G+ +P F N QLG+ +S
Sbjct: 1702 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1733
Query: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 804
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 1734 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1790
Query: 805 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 859
P + S C +P +TF + H SP L
Sbjct: 1791 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1841
Query: 860 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 902
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 1842 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1901
Query: 903 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 956
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 1902 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1961
Query: 957 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1016
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 1962 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 2008
Query: 1017 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
L+ E + G S PP R IS +
Sbjct: 2009 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 2042
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 2043 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 2097
Query: 1135 AEC 1137
C
Sbjct: 2098 RVC 2100
Score = 68.9 bits (167), Expect = 8e-11
Identities = 74/285 (25%), Positives = 118/285 (41%), Gaps = 34/285 (11%)
Query: 171 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
Query: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----T 284
PIC CG ++G S + N +H + T+ PG +F
Sbjct: 156 NETPIC-DRIPCGLPPTITNGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEP 211
Query: 285 DFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQV 344
D + I P + PP + +N + V+D+ + + +
Sbjct: 212 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSL 258
Query: 345 KKAIDFKSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFS 399
+ ++F+ + + G K LN E + + S +C PD E +R +FS
Sbjct: 259 NEVVEFRCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFS 317
Query: 400 LGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
G V +SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 318 PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 358
Score = 67.8 bits (164), Expect = 2e-10
Identities = 77/295 (26%), Positives = 121/295 (41%), Gaps = 25/295 (8%)
Query: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 1900 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1958
Query: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEP-GDTISLIFTDFQM 288
PIC +C S+G S + +HN T+ P G+ + F++
Sbjct: 1959 KKAPICEI-ISCEPPPTISNGDFYSNN-RTSFHNGTVVTYQCHTGPDGEQL------FEL 2010
Query: 289 EEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
+ + +W S PPP + N V ++ R G + + + + I
Sbjct: 2011 VGERSIYCTSKDDQVGVWSS----PPPRCISTNKCTAPEV-ENAIRVPGNRSFFTLTEII 2065
Query: 349 DFKSR-GFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTV 404
F+ + GF + + + + S +C P E +G+ S +FS G V
Sbjct: 2066 RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEV 2125
Query: 405 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 458
+SC+ Y L+GA S+ C + WS P C VK+C L Q P G P
Sbjct: 2126 FYSCEPSYDLRGAASLHCTPQGD----WSPEAPRCTVKSCDDFLGQLPHGRVLLP 2176
Score = 65.9 bits (159), Expect = 7e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 590 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 629
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 1360 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 1419
Query: 630 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 685
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 1420 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1464
Query: 686 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 736
T +V S + + H L A+ +SG + + P G+P
Sbjct: 1465 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1523
Query: 737 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 786
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 1524 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1581
Query: 787 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 844
C P C + +G+++S + SLN +PG +K LN
Sbjct: 1582 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1637
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 896
E+ + P +G P + S + ++ + G +H
Sbjct: 1638 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1697
Query: 897 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 950
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 1698 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1757
Query: 951 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 1758 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1808
Query: 1002 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1057
FN T D H NG ++ P R S F + I+
Sbjct: 1809 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1862
Query: 1058 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1092
DF S++YE F FS LE C P P G I
Sbjct: 1863 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1922
Query: 1093 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1150
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1923 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1982
Query: 1151 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1210
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1983 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 2032
Query: 1211 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1246
R + T N + + N E GF +V + +
Sbjct: 2033 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 2092
Query: 1247 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1300
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 2093 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 2150
Query: 1301 YPLPSCIAECGGRFKGE-SSGRILSP 1325
P C + F G+ GR+L P
Sbjct: 2151 PEAPRCTVKSCDDFLGQLPHGRVLLP 2176
Score = 63.9 bits (154), Expect = 3e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
Query: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
C G T T+ +F ++TN+ NF + + Y
Sbjct: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
Query: 561 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
Query: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 676
S P VL + + +N + PG + S +DL G
Sbjct: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 677 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 726
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 727 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 764
E CP P + N R G + F G +++ C+
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
Query: 765 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 798
G TI C G +WS P+CG GH AP
Sbjct: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
Score = 62.8 bits (151), Expect = 6e-09
Identities = 137/619 (22%), Positives = 201/619 (32%), Gaps = 134/619 (21%)
Query: 584 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 635
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 692
G N C DP SF D ES + G+ S +P G +
Sbjct: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
Query: 693 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 731
P H T+ S L+++ GR F+IT + C
Sbjct: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
Query: 732 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 789
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
Query: 790 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 844
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 899
+ + GP + V L S + ++ L R GF + +
Sbjct: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
Query: 900 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 947
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 948 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
Query: 1006 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1065
L GS + AG+ + + +
Sbjct: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
Query: 1066 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1116
C P + G G F G T+ ++C + + L G S I
Sbjct: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 918
Query: 1117 ICLGG--GRRVWSAPLPRC 1133
C G VWS+P PRC
Sbjct: 919 RCTSDPQGNGVWSSPAPRC 937
Score = 60.5 bits (145), Expect = 3e-08
Identities = 132/647 (20%), Positives = 223/647 (34%), Gaps = 127/647 (19%)
Query: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSCIA 1308
C +P P G +G GS I Y C GY L GSS C+ +G+ WD P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1309 ECGGRFKGESSGRILSPGYP-FPYDN--NLRCMWMIEVDPGNIVSLQFL-----AFDTEA 1360
G ++G +S F Y + RC +PG+ F + +
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRC------NPGSGGRKVFELVGEPSIYCTS 217
Query: 1361 SHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN--IVTIQFDTDF-----YISKSGFA 1413
+ D + +W GP ++ + + + GI + N + ++ +F ++ K
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
Query: 1414 IQFSS---------SVATACRDPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEER 1461
++ + S + C+ P ++ R + D PG V + C+PGY+L+G
Sbjct: 278 VKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 337
Query: 1462 ITCIQVENRYFWQPSPPVCIAPCGGNLTGS--SGFILSPNFPHPYPHSRDCDWTITVNAD 1519
+ C + W P+ P C + G +G +L P
Sbjct: 338 MRCTPQGD---WSPAAPTCEVKSCDDFMGQLLNGRVLFP--------------------- 373
Query: 1520 YVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS 1579
++ + DF+ D L GS + +ES N+
Sbjct: 374 -------VNLQLGAKVDFVC-----DEGFQLKGSSASYCVLAGMESLWNS---------- 411
Query: 1580 VSYTGFHLEYKAKLRESCFDPGN--IMNGTRLGMD---YKLGSTVTYYCD------AGYV 1628
+ E F P I NG G + G TV Y CD +
Sbjct: 412 ----------SVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 1629 LQGYSTLTCIMGDDGRPGWNRALP------SCHAPCGSRSTGSEGTVLSPNYPKNYSVGH 1682
L G ST+ C G W+ P C AP + + ++P S+ +
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 1683 NC-VYSIAVPKEFVVFGQFVFFQTSLHDVVE---VYDGPTQQSSLLSSLSGSHSGESLPL 1738
C P V+ +S DV + P + ++ ++ G +
Sbjct: 522 ECRPEYYGRPFSITCLDNLVW--SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 1739 S--SGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVG 1793
S +G+++ ++ ++ H+ + P C P G I F G
Sbjct: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKP-PICQRIPCGLPPTIANGDFISTNRENFHYG 638
Query: 1794 SSVLFDCNPG------YILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1834
S V + CNPG + L G +I C + + + W+ P CI+P
Sbjct: 639 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 60.1 bits (144), Expect = 4e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 705 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 753
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
Query: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 812
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
Query: 813 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 867
S+ PG + FE N D + + GP +P N P
Sbjct: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
Query: 868 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 910
L S + ++ L R GF + + +N + C P
Sbjct: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
Query: 911 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 967
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 968 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1025
G +G +L +P +L VD +G Q
Sbjct: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
Query: 1026 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1085
L GS + AG+ + + + C P +
Sbjct: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
Query: 1086 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1133
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 59.7 bits (143), Expect = 5e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 1078 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1134
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1135 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1184
CG T G +S N EN H + + + G G + F L
Sbjct: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
Query: 1185 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1239
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 1240 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1287
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
Query: 1288 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1346
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
Query: 1347 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1402
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
Query: 1403 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1456
G TV + CDP ++L
Sbjct: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
Query: 1457 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1512
GE I C + W P C G G +P+ F + D+
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
Query: 1513 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1559
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
Query: 1560 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1611
RI S T H L S +G + K R C P I NG +
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
Query: 1612 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1657
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
Score = 54.7 bits (130), Expect = 2e-06
Identities = 61/257 (23%), Positives = 92/257 (35%), Gaps = 50/257 (19%)
Query: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
FS +V+ F CQ GF + G + + CQ N+W +P C S P VL + +
Sbjct: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPDVLHAERTQ 760
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
+N + PG + S +DL GD SP +P + +
Sbjct: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
Query: 694 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 730
L N +L +++F D +G + +Y E C
Sbjct: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
Query: 731 PDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQGTETITCIL-MDGKVMWS 781
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 872 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 782 GLIPKCGAPCGGHFSAP 798
P+CG GH AP
Sbjct: 932 SPAPRCGIL--GHCQAP 946
Score = 54.7 bits (130), Expect = 2e-06
Identities = 61/257 (23%), Positives = 92/257 (35%), Gaps = 50/257 (19%)
Query: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
FS +V+ F CQ GF + G + + CQ N+W +P C S P VL + +
Sbjct: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPDVLHAERTQ 1210
Query: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
+N + PG + S +DL GD SP +P + +
Sbjct: 1211 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 1262
Query: 694 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 730
L N +L +++F D +G + +Y E C
Sbjct: 1263 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 1321
Query: 731 PDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQGTETITCIL-MDGKVMWS 781
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 1322 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 1381
Query: 782 GLIPKCGAPCGGHFSAP 798
P+CG GH AP
Sbjct: 1382 SPAPRCGIL--GHCQAP 1396
Score = 49.3 bits (116), Expect = 7e-05
Identities = 70/277 (25%), Positives = 100/277 (36%), Gaps = 34/277 (12%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 1454 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNTAHWSTKPPICQ 1512
Query: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 1513 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1566
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
G P + P+ ++VS + ++ + E GF
Sbjct: 1567 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1626
Query: 549 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 596
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 1627 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1686
Query: 597 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 631
S+ C WS P C +F P G VL P
Sbjct: 1687 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1723
Score = 48.1 bits (113), Expect = 2e-04
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 590 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 626
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 1810 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1869
Query: 627 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 679
T L+ + GY + N +W+ + D R K P
Sbjct: 1870 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1910
Query: 680 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 731
P G T + S + S + RL + G N+T++ C
Sbjct: 1911 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1970
Query: 732 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 782
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 1971 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 2030
Query: 783 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 837
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 2031 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 2090
Query: 838 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 895
+L + P +L L + Q +F S Y L +
Sbjct: 2091 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 2150
Query: 896 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 950
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 2151 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 2210
Query: 951 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1010
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 2211 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 2257
Query: 1011 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1054
+ + LI E NG ++ P R PP I G Y L
Sbjct: 2258 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 2316
Query: 1055 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1096
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 2317 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 2374
Query: 1097 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1135
GD +T C GY LEG+ C R W PL +C +
Sbjct: 2375 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 2417
Score = 47.0 bits (110), Expect = 3e-04
Identities = 68/277 (24%), Positives = 101/277 (36%), Gaps = 34/277 (12%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNAAHWSTKPPICQ 612
Query: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
G P + P+ ++VS + ++ + E GF
Sbjct: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 549 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 596
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
Query: 597 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 631
S+ C WS P C +F + G VL P
Sbjct: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
Score = 47.0 bits (110), Expect = 3e-04
Identities = 68/277 (24%), Positives = 101/277 (36%), Gaps = 34/277 (12%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNAAHWSTKPPICQ 1062
Query: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 1116
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
G P + P+ ++VS + ++ + E GF
Sbjct: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
Query: 549 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 596
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 1177 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 597 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 631
S+ C WS P C +F + G VL P
Sbjct: 1237 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 1273
Score = 46.6 bits (109), Expect = 4e-04
Identities = 187/905 (20%), Positives = 284/905 (31%), Gaps = 270/905 (29%)
Query: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 456
+ LG+ V F CDE + L+G+ + C +A + + W+ PVC+ C S P+G T
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCV-LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHT 883
Query: 457 SPN---FPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGD----GGEVGD 509
FPF N C FDL IG T+ G
Sbjct: 884 GKPLEVFPFGKTVNYTC----------DPHPDRGTSFDL-IGESTIRCTSDPQGNGVWSS 932
Query: 510 PRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY----------------- 552
P +L PD + L QT+ S +G + Y
Sbjct: 933 PAPRCGILGHCQAPDHFLFAK----LKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLD 988
Query: 553 -------KEI-EKESCGDPGTPLYG-IREGDGFSNRDVLRFECQFGFELIGEKSIVCQEN 603
K++ +++SC P P+ G + + + C G LIG S C +
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 604 N---QWSANIPIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTII 648
WS PIC PC T G +S + Y G+ ++ ++
Sbjct: 1049 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 1108
Query: 649 SDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 708
+P I+ + ND D + + G +P+ I
Sbjct: 1109 GEPS--IYCTSND-------DQVGIWSGPAPQCII------------------------- 1134
Query: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQG 765
N+C P + N DN F L + C+ GF+ +G
Sbjct: 1135 ------------------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKG 1174
Query: 766 TETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVI-----------LSPGWPGYYKDS 814
+ C ++ W +P C C P V+ SPG +Y
Sbjct: 1175 PRRVKCQALN---KWEPELPSCSRVC----QPPPDVLHAERTQRDKDNFSPGQEVFY--- 1224
Query: 815 LNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSS 874
+CE + S++ T + EV + + LL V L +
Sbjct: 1225 -SCEPGYDLRGAASMRCT-PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKV 1282
Query: 875 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPV-------------HGRRYGHD 921
+F+ D G Y V S + +PV +GR G
Sbjct: 1283 DFV-----CDEGFQLKGSSASY-CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKP 1336
Query: 922 ---FSIGSTVSFSCD------SGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVR 968
F G V+++CD + + L E + C + N WS P P C L G +
Sbjct: 1337 LEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQ 1394
Query: 969 GPS------------------GTILS-PGYPEFY--PNSLNC----TWT----------- 992
P GT L PE+Y P S+ C W+
Sbjct: 1395 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSC 1454
Query: 993 --------------VDVTHGKGVQFNFHTFH-LEDHHDYLLI----TENGSFTQPLARLT 1033
D+ G + ++ T H L H I T + S P+ +
Sbjct: 1455 KTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRI 1514
Query: 1034 GSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFN 1093
LPPTI G + S + E F+ YGS + +
Sbjct: 1515 PCGLPPTIANGDF------------ISTNRENFH------------------YGSVVTYR 1544
Query: 1094 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV--WSAPLPRCVAECGASATNNE-GILLS 1150
+G + L G I C +V WS P P+C+ + N E GIL+S
Sbjct: 1545 CNLGS----RGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVS 1600
Query: 1151 PNYPL 1155
N L
Sbjct: 1601 DNRSL 1605
Score = 46.6 bits (109), Expect = 4e-04
Identities = 110/502 (21%), Positives = 165/502 (32%), Gaps = 160/502 (31%)
Query: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 1187 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 1243
Query: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
W P C +D G + G FP A + V + G
Sbjct: 1244 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 1289
Query: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
FQ++ Y + G E ++W S + + PP+I N H
Sbjct: 1290 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPN-----------GRH 1332
Query: 334 RYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKR 393
+ + KA+++ P D F ++ E I+ S+ + R
Sbjct: 1333 TGKPLEV-FPFGKAVNYTCD-----PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPR 1386
Query: 394 IG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 431
G SDF +G+++++ C +Y + SITC
Sbjct: 1387 CGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NLV 1441
Query: 432 WSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFD 491
WS + VCK K+C + +G V VIT D
Sbjct: 1442 WSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT---------------D 1470
Query: 492 LEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
+++ G + T L G + I+S ++ W T +
Sbjct: 1471 IQV---------GSRINYSCTTGHRLIGHSSAECILSGNTAHW---STKPPI-------- 1510
Query: 552 YKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKSI 598
++ CG P T I GD S NR+ V+ + C G FEL+GE SI
Sbjct: 1511 ---CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSI 1563
Query: 599 VCQENNQ----WSANIPICIFP 616
C N+ WS P CI P
Sbjct: 1564 YCTSNDDQVGIWSGPAPQCIIP 1585
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 1423 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1480
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 1481 IAPCGGNLTGSSGFILSPN 1499
PCG T ++G +S N
Sbjct: 163 RIPCGLPPTITNGDFISTN 181
Score = 44.7 bits (104), Expect = 0.002
Identities = 112/503 (22%), Positives = 165/503 (32%), Gaps = 162/503 (32%)
Query: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
Query: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
W P C +D G + G FP A + V + G
Sbjct: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 389
Query: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
FQ++ Y + G E ++W S + + PP+I N
Sbjct: 390 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPNG------------- 430
Query: 334 RYRGFSAPYQVKKAIDF-KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGK 392
R P +V F K+ + P D F ++ E I+ S+ +
Sbjct: 431 --RHTGKPLEV---FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 485
Query: 393 RIG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFA 430
R G SDF +G+++++ C +Y + SITC
Sbjct: 486 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NL 540
Query: 431 AWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEF 490
WS + VCK K+C + +G V VIT
Sbjct: 541 VWSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT--------------- 569
Query: 491 DLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
D+++ G + T L G + I+S ++ W T +
Sbjct: 570 DIQV---------GSRINYSCTTGHRLIGHSSAECILSGNAAHW---STKPPI------- 610
Query: 551 NYKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKS 597
++ CG P T I GD S NR+ V+ + C G FEL+GE S
Sbjct: 611 ----CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
Query: 598 IVCQENNQ----WSANIPICIFP 616
I C N+ WS P CI P
Sbjct: 663 IYCTSNDDQVGIWSGPAPQCIIP 685
Score = 44.7 bits (104), Expect = 0.002
Identities = 112/503 (22%), Positives = 165/503 (32%), Gaps = 162/503 (32%)
Query: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
Query: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
W P C +D G + G FP A + V + G
Sbjct: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 839
Query: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
FQ++ Y + G E ++W S + + PP+I N
Sbjct: 840 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPNG------------- 880
Query: 334 RYRGFSAPYQVKKAIDF-KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGK 392
R P +V F K+ + P D F ++ E I+ S+ +
Sbjct: 881 --RHTGKPLEV---FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 935
Query: 393 RIG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFA 430
R G SDF +G+++++ C +Y + SITC
Sbjct: 936 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NL 990
Query: 431 AWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEF 490
WS + VCK K+C + +G V VIT
Sbjct: 991 VWSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT--------------- 1019
Query: 491 DLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
D+++ G + T L G + I+S ++ W T +
Sbjct: 1020 DIQV---------GSRINYSCTTGHRLIGHSSAECILSGNAAHW---STKPPI------- 1060
Query: 551 NYKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKS 597
++ CG P T I GD S NR+ V+ + C G FEL+GE S
Sbjct: 1061 ----CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 1112
Query: 598 IVCQENNQ----WSANIPICIFP 616
I C N+ WS P CI P
Sbjct: 1113 IYCTSNDDQVGIWSGPAPQCIIP 1135
Score = 41.6 bits (96), Expect = 0.014
Identities = 57/260 (21%), Positives = 99/260 (38%), Gaps = 43/260 (16%)
Query: 194 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 252
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 1866 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1919
Query: 253 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 310
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 1920 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1972
Query: 311 NIPPPIISNKNWLRLHFVTDSNHR---YRGFSAPYQVKKAID----FKSRGFKLFPGKDN 363
P ISN ++ SN+R + G YQ D F+ G +
Sbjct: 1973 ----PTISNGDFY-------SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 2021
Query: 364 SNKFSILNEGGIKTAS-NLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKS 419
++ + + + S N C P E EN R+ + F+L ++F C +V+ G+ +
Sbjct: 2022 DDQVGVWSSPPPRCISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 2080
Query: 420 ITCQRIAEVFAAWSDHRPVC 439
+ CQ W P C
Sbjct: 2081 VQCQ----TNGRWGPKLPHC 2096
Score = 37.0 bits (84), Expect = 0.35
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 382 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 438
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 2298 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 2353
Query: 439 CKVKTC 444
CK C
Sbjct: 2354 CKEVNC 2359
Score = 33.9 bits (76), Expect = 2.9
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 2178 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 2224
Score = 33.5 bits (75), Expect = 3.8
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 1964 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2011
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 2378 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 2423
Score = 32.7 bits (73), Expect = 6.5
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 225 TASWDFPVPICRAEDAC 241
W P P C + C
Sbjct: 672 VGIWSGPAPQCIIPNKC 688
Score = 32.7 bits (73), Expect = 6.5
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 1121
Query: 225 TASWDFPVPICRAEDAC 241
W P P C + C
Sbjct: 1122 VGIWSGPAPQCIIPNKC 1138
Score = 32.7 bits (73), Expect = 6.5
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 1512 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1571
Query: 225 TASWDFPVPICRAEDAC 241
W P P C + C
Sbjct: 1572 VGIWSGPAPQCIIPNKC 1588
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 333 bits (853), Expect = 2e-90
Identities = 294/1082 (27%), Positives = 426/1082 (39%), Gaps = 144/1082 (13%)
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ--MDGAPPVC 2348
C PPP+ N I +G +IRY C F L+G L C +++ D P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2349 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2408
+ Y + Y + C I V GY I
Sbjct: 83 E--------------------YFNKYSS---CPEPI-VPGGYKIRG-------------- 104
Query: 2409 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHE-VFLQWSADHGNNKKGFRIRYIAFYCST 2467
+P S ++ N + NG++ V+ Q + G + + C
Sbjct: 105 --------STPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
Query: 2468 PESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2525
+G+ S+ G + V ++C+ G+ LVG+ C S W A P C+
Sbjct: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG----KWSAVPPTCEE 212
Query: 2526 ISCGIPKAPTNGGILTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSNHNKTP 2583
C NG + L VG +FC++GYRL + V G W+ K P
Sbjct: 213 ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT---KMP 269
Query: 2584 RCVVISCGELPTPPNGNKIGTQ---TSYGSTAIFTCD------LGFMLVGSAVRECL--- 2631
C I C P NG IG SYGS +TCD + F+L+G + C
Sbjct: 270 VCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDS 329
Query: 2632 -SSGLWSESETRC----LAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSS 2684
+G WS RC A C P+++ V G+ Y Y DTV++ C GF L GS
Sbjct: 330 QKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSK 389
Query: 2685 VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNG---FNFNDVVTFSCNIGYLMQGP 2741
C W P C C P + + G+ F+ + +SCN GY++ G
Sbjct: 390 QIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGE 448
Query: 2742 TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF 2801
QC + W+ P P CKV C G +K + + + V C GY L
Sbjct: 449 ESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD------VNSSCGEGYKLS 502
Query: 2802 GSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTG---- 2854
GS CQ W + C I C P V N +G E + +G+TV Y+C
Sbjct: 503 GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPER 562
Query: 2855 --KRSLLGQSSRTCQLN----GHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRT 2905
+ SL+G+S+ C N G WSG P C +G S +E+ +
Sbjct: 563 GVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFY 622
Query: 2906 KSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT-----TANGKVFRID 2960
TV + C +G+ L GS + C A+ +W P C+ PG T VF +
Sbjct: 623 NDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVS 682
Query: 2961 GTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDY 3020
G T V Y+C GY+L G C +G WS + P C +C L G
Sbjct: 683 GMT----VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-TCQHVRQSLQELPAGSRV 737
Query: 3021 VVGQNVSYMCQPGYTMELNGSRIRTC--TINGTWSGVMPTCRAVTCPTPPQISNGRLEGT 3078
+ V+ CQ GY +L G + C NG W +P C+ + C PP I NG+ G
Sbjct: 738 EL---VNTSCQDGY--QLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGM 792
Query: 3079 ---NFDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPK----FCGDPGI 3127
NF +G +SY C G+ L L C G+G+WSG PQCL C +P +
Sbjct: 793 MAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV 852
Query: 3128 PAQGK--REGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCEN 3185
K + ++ + V CN FI+ GS C D TW P CI+ C
Sbjct: 853 KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPP 912
Query: 3186 PGVPRHGSQNNTFG----FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHS 3241
P P+ + N+T G F G + + C +G+LL G C + TWS P C +
Sbjct: 913 P--PKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
Query: 3242 CKQPE--TPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3299
C P + + +G + C+ G+ L G + + C+SD+ W + +C +
Sbjct: 971 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQ-CQSDHQWNPPLAVCRS 1029
Query: 3300 GS 3301
S
Sbjct: 1030 RS 1031
Score = 225 bits (573), Expect = 7e-58
Identities = 188/661 (28%), Positives = 270/661 (40%), Gaps = 75/661 (11%)
Query: 2699 PSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQC----QANRQW 2752
P + +SCG P + GR S V+ +SC+ + + G C + + W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 2753 SHPPPMCKVVN----CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2808
P P C+ N C +P +P K + +G V + C + + G+ + C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP---YRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 2809 QPNGQWDKP-LPECIMI---DCGHPGVPPNAVLSGE---KYTFGSTVHYSCTGKRSLLGQ 2861
Q N W LP C+ + +C + N + E G +V YSC L+G+
Sbjct: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Query: 2862 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTVRYACDTGYILH 2920
C +G WS P C C G +G +E R T + CD GY L
Sbjct: 193 KIINCLSSGKWSAVPPTCE---EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
Query: 2921 GSEERTCLANG---SWTGRQPECKAVQCGNPGTTANGKVF--RIDGTTFSSSVIYSC--- 2972
G C+ G +WT + P C+ + C +P NG+ + ++ S V Y+C
Sbjct: 250 GPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
Query: 2973 -MEG--YILSGPSVRQCTAN----GTWSGTLPNCTI----ISCGDPGIPANGLRYG--DD 3019
EG +IL G S +CT + GTWSG P C + + C P I + G D
Sbjct: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR 368
Query: 3020 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG-- 3077
Y V + C G+T L GS+ C GTW P C C PP I NG+ E
Sbjct: 369 YTYNDTVIFACMFGFT--LKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRH 425
Query: 3078 -TNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGK 3136
FD G SI Y C+PGY L + C G W+ VPQC C G K + +
Sbjct: 426 MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
Query: 3137 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3196
+ +V+ SC + L GS + CQ W C E T C P V +G+
Sbjct: 486 --FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT---CPPPPVIYNGAHTG 540
Query: 3197 TF--GFQVGSVVQFHCKKG-------HLLQGSTTRTCLPDL---TWSGIQPEC----IPH 3240
+ F G+ V + C G L+ ST R D TWSG P C +
Sbjct: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
Query: 3241 SCKQPETPAHANVVGMDLP-SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3299
C + G + P + T+ + C GF L G ++ R C++DNTW ++P+CE
Sbjct: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR-CKADNTWDPEIPVCEK 659
Query: 3300 G 3300
G
Sbjct: 660 G 660
Score = 198 bits (504), Expect = 7e-50
Identities = 223/907 (24%), Positives = 348/907 (38%), Gaps = 143/907 (15%)
Query: 2139 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE-ALCGGNITAMNGTIYSP---- 2193
G ++++ C GY L+G + CL S W+ P CE A C NG + P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLS--SGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
Query: 2194 -GYPDEYPNFQDCFWLVRVPPGNGIYI--NFTVLQTEPIYDFITVWDGPD-QNSPQIGQF 2249
G + F D + ++ PP + I P+ + I P N IG
Sbjct: 234 VGVTANF--FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNS 291
Query: 2250 SGNTALESVYSTS---------NQILI-----KFHSDFTTSGFFV-------LSYHAYQL 2288
N + S+ + + N ILI + D +G + LS A Q
Sbjct: 292 LANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ- 350
Query: 2289 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2348
C P + + + D + D + + C+ GFTL G+ + C + + + PVC
Sbjct: 351 --CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA--QGTWEPSAPVC 406
Query: 2349 QVLCPA-----NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK 2403
+ C A N + D V PG Y S GY + + E Q
Sbjct: 407 EKECQAPPNILNGQKEDRHMVRFDPGTSIKY----------SCNPGY-VLVGEESIQCTS 455
Query: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVF---LQWSADHGNNKKG----- 2455
E V+ P Q V + + +T H+ + S G G
Sbjct: 456 E----GVWTPPVPQCKVAAC---EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQE 508
Query: 2456 --------FRIRYIAFYCSTPESPPHGYIISQTGGQLN-----SVVRWACDRG------F 2496
IR P PP Y + TG L + V + C+ G F
Sbjct: 509 CQGTIPWFMEIRLCKEITCPP--PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEF 566
Query: 2497 RLVGKSSAVCRKSSYGYHAWDAPVPACQ----AISCGIPKAPTNGGILTTD--YLVGTRV 2550
L+G+S+ C + W P P C+ A+ C I + Y V
Sbjct: 567 SLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTV 626
Query: 2551 TYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSY-- 2608
T+ C G+ L K + C++D TW + P C C P +G G T +
Sbjct: 627 TFKCYSGFTL--KGSSQIRCKADNTWDP--EIPVCEK-GCQSPPGLHHGRHTGGNTVFFV 681
Query: 2609 -GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC--LAGHC--GIPELIVNGQVIGEN 2663
G T +TCD G++LVG+ C+ SG WS S RC H + EL +V
Sbjct: 682 SGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV---- 737
Query: 2664 YGYRDTVVYQCNPGFRLIGSSVRICQQDHN--WSGQLPSCVPVSCGHPGSPIYGRTSG-- 2719
+ V C G++L G + ++CQ N W ++P C + C P + G+ +G
Sbjct: 738 ----ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMM 793
Query: 2720 -NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ----WSHPPPMC----KVVNCSDPGIP 2770
F + + V++ C+ G+ + G K QC+++ + WS P P C V C +P +
Sbjct: 794 AENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVK 853
Query: 2771 ANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI---MIDCG 2827
K H +++ +V+ DCNPG+ + GS V+ C + W +P CI I C
Sbjct: 854 HGYKLNKT--HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
Query: 2828 HPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDAT 2884
P PN +G +++ G ++ YSC L+G++ C G WS PHC
Sbjct: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
Query: 2885 GTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKA-- 2942
+ D G ++ + V C+ GY+L GS + C ++ W C++
Sbjct: 972 SSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRS 1031
Query: 2943 ---VQCG 2946
V CG
Sbjct: 1032 LAPVLCG 1038
Score = 99.0 bits (245), Expect = 7e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 3055 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3108
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 3109 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3163
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 3164 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3218
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 3219 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3278
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 3279 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3312
R + WT K+P+CE +I P P L
Sbjct: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
Score = 85.1 bits (209), Expect = 1e-15
Identities = 182/861 (21%), Positives = 272/861 (31%), Gaps = 226/861 (26%)
Query: 1616 GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH-APCGSRSTGSEGTVLSP-- 1672
G +VTY C++GY+L G + C+ W+ P+C A C S G V P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKVKEPPI 231
Query: 1673 ---NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1729
N+ V+ GQ V + T + E++ S L+G
Sbjct: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFC-----PSPPPILNG 285
Query: 1730 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR--------------------- 1768
H G SL S I P F + ++ R
Sbjct: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELS 345
Query: 1769 TSSTQCSSVPEPRF--GRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
TS+ QC P P+ GR + + + +V+F C G+ L GS IRC N+
Sbjct: 346 TSAVQC---PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGT 398
Query: 1824 WNDSLPTCIVPCGG---ILTKRK----------GTIL----SPGYPEPYDNNLNC----V 1862
W S P C C IL +K GT + +PGY + ++ C V
Sbjct: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
Query: 1863 WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLY 1922
W VP Q A E L P + S G S ++Y
Sbjct: 459 WTPPVP-------QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-----KLSGSVY 506
Query: 1923 LNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCDQG-- 1977
Q I + +E +CP P +G G + + G V++ C+ G
Sbjct: 507 QECQGTIP-----WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Query: 1978 ----YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDC 2033
+SL G S I C R + P L + S V ++ G+ S +
Sbjct: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYK---ISGKEA 618
Query: 2034 TWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHET 2093
+ N + F + F GSS+ P+IP
Sbjct: 619 PYFYNDTVTFKCYSGFT-------------LKGSSQIRCKADNTWDPEIPVCE------- 658
Query: 2094 SLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND---FTVGQTISFECFPGY 2150
+ C P +G G + F G T+ + C PGY
Sbjct: 659 ------------------------KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGY 694
Query: 2151 TLIGNSALTCLHGVSRNWNHPLPRCEALC-----------GGNITAMNGTIYSPGYPDEY 2199
L+GN ++ C+ S NW+ PRCE C G+ + T GY
Sbjct: 695 LLVGNKSIHCM--PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 752
Query: 2200 PNFQDC------FWLVRVP----------------------PGNGIYINFTVLQTEPIYD 2231
+Q C W ++P N +Y N + + +
Sbjct: 753 HAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY 812
Query: 2232 FI--------------TVWDGPDQN-----------SPQIGQFSGNTALESVYSTSNQIL 2266
+ W GP +P++ S YS ++ +
Sbjct: 813 LLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVY 872
Query: 2267 IKFHSDFTTSGFFVLSYHAYQLRV-------------CQPPPPVPNAEILTED-DEFEIG 2312
+ + F +G V+ H V C PPP PN + F G
Sbjct: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPG 932
Query: 2313 DIIRYQCLPGFTLVGNAILTC 2333
I Y C G+ LVG A+L C
Sbjct: 933 MSILYSCDQGYLLVGEALLLC 953
Score = 80.5 bits (197), Expect = 3e-14
Identities = 156/664 (23%), Positives = 237/664 (35%), Gaps = 164/664 (24%)
Query: 1094 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPN 1152
F G ++ +SC+ GY L G I C G VW+ P+P+C VA C A+ +L P
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG--VWTPPVPQCKVAACEATGRQ---LLTKPQ 483
Query: 1153 YP-LNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---LKIYDGKDKTTH-----LL 1203
+ + + N C G+G +S + QG + ++I K+ T
Sbjct: 484 HQFVRPDVNSSC--------GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN 535
Query: 1204 GAFTGASMR----GLTLSSTSN---QLWLEF------------NSDTEGTDEG-FQLVYT 1243
GA TG+S+ G T++ T N + +EF N GT G L
Sbjct: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
Query: 1244 SFELSHCEDPGIPQFGYKIS--DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1301
S C I GYKIS + +F T+ + C G+TL GSS ++C WD
Sbjct: 596 SLLAVQCSHVHIAN-GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD--NTWDP 652
Query: 1302 PLPSCIAEC-------GGRFKGESSGRILS---------PGYPFPYDNNLRCMWMIEVDP 1345
+P C C GR G ++ +S PGY + ++ CM
Sbjct: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM-----PS 707
Query: 1346 GNIVSLQFLAFDTEASHDILRVWD-GPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTD 1404
GN W P + + + SL S + +V
Sbjct: 708 GN--------------------WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDG 747
Query: 1405 FYISKSGFAIQFSSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVF 1448
+ + +G A Q C P V +NG G E G+ V +
Sbjct: 748 YQL--TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSY 805
Query: 1449 QCDPGYELQGEERITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNF 1500
+CD G+ L GE+++ C + W SPPV P N G+ L+
Sbjct: 806 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH 862
Query: 1501 PHPYPHSR----DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQ 1555
Y H+ DC+ +N VI + D ++ P IG
Sbjct: 863 -SAYSHNDIVYVDCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPP 912
Query: 1556 DSKLPERIESSSNTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RES 1596
K P + N F S+ Y+ G+ L +A L +
Sbjct: 913 PPKTPNGNHTGGNIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
Query: 1597 CFDPGNIMNGTRLGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
C P + M+G + G++ Y+ G+ VT C+ GY+L+G C WN L
Sbjct: 971 CSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLA 1025
Query: 1653 SCHA 1656
C +
Sbjct: 1026 VCRS 1029
Score = 72.4 bits (176), Expect = 7e-12
Identities = 138/646 (21%), Positives = 228/646 (35%), Gaps = 124/646 (19%)
Query: 1614 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1672
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
Query: 1673 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1728
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
Query: 1729 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1773
+ L + SG + T+ F + T KG + ++ +
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
Query: 1774 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
Query: 1831 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1865
C + C +LTK + + P Y E P+ + +I
Sbjct: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
Query: 1866 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 1919
T P V + H SL+ + G N P G + TSN
Sbjct: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
Query: 1920 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 1976
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 1977 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGF-PGNYPSSLDCTW 2035
G++L+G S I C W+ IP+C C PG G + +
Sbjct: 633 GFTLKGSSQIRCKAD--NTWDPEIPVCEKGCQS----------PPGLHHGRHTGGNTVFF 680
Query: 2036 TINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSL 2095
+ + + ++ ++IH + SG+ S + + SL + +
Sbjct: 681 VSGMTVDYTCDPGYLLVGNKSIHC---MPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
Query: 2096 YFHSDYSQNKQGFHIVYQAYQLQS------------------CPDPRPFRNG---FVIGN 2134
+ Q+ G+ + AYQ+ C P NG ++
Sbjct: 738 ELVNTSCQD--GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
Query: 2135 DFTVGQTISFECFPGYTLIGNSALTCL-----HGVSRNWNHPLPRC 2175
+F G +S+EC G+ L+G L C HG +W+ P P+C
Sbjct: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPSPQC 838
Score = 63.9 bits (154), Expect = 3e-09
Identities = 104/435 (23%), Positives = 158/435 (36%), Gaps = 78/435 (17%)
Query: 1444 DTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHP 1503
DTV F+C G+ L+G +I C + +N W P PVC C SP H
Sbjct: 624 DTVTFKCYSGFTLKGSSQIRC-KADNT--WDPEIPVCEKGCQ-----------SPPGLHH 669
Query: 1504 YPHSRDCDWTITVNADYVISLAFISFSIEPNYDFL---YIYDGPDSN-SP---------- 1549
H+ N + +S + ++ +P Y + I+ P N SP
Sbjct: 670 GRHTGG-------NTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ 722
Query: 1550 -LIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRE-------SCFDPG 1601
+ S Q+ R+E + + ++ G E ++ C P
Sbjct: 723 HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPP 782
Query: 1602 NIMNGTRLGM---DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC-HAP 1657
I+NG GM ++ G+ V+Y CD G+ L G L C G W+ P C +P
Sbjct: 783 VIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSP 842
Query: 1658 CGSRSTGSEGTVLSPNYPKNYS---VGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVY 1714
+R E + Y N + HN + + F++ G V + D V
Sbjct: 843 PVTRCPNPE---VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT--DNTWVP 897
Query: 1715 DGPTQQSSLL-------SSLSGSHSGESLP-LSSGNQITIR----FTSVGPITAKGFH-- 1760
PT + +G+H+G ++ S G I + VG H
Sbjct: 898 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 957
Query: 1761 FVYQAVPRTSSTQCSSVPEPRFGRRIGNE----FAVGSSVLFDCNPGYILHGSIAIRCET 1816
Q P CSS P G + G E + G+ V +C GY+L GS +C+
Sbjct: 958 TWSQPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ- 1015
Query: 1817 VPNSLAQWNDSLPTC 1831
S QWN L C
Sbjct: 1016 ---SDHQWNPPLAVC 1027
Score = 62.4 bits (150), Expect = 8e-09
Identities = 145/624 (23%), Positives = 214/624 (34%), Gaps = 142/624 (22%)
Query: 925 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 977
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 978 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1028
GY P S C V G+GV + + + E P
Sbjct: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
Query: 1029 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1088
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
Query: 1089 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1148
NF + T C+ + GT WS P PRC A + IL
Sbjct: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
Query: 1149 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1193
Y N C++ ++ K I +A+ V + I
Sbjct: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Query: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1253
+G+ + H++ G S++ S + L + T EG V+T + C+
Sbjct: 418 NGQKEDRHMVRFDPGTSIK----YSCNPGYVLVGEESIQCTSEG---VWTP-PVPQCKVA 469
Query: 1254 GIPQFGYKI--SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAEC 1310
G ++ Q F + C GY L GS +C W + C C
Sbjct: 470 ACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ--GTIPWFMEIRLCKEITC 527
Query: 1311 GGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1363
+ G +G L FPY + +PG ++F S+D
Sbjct: 528 PPPPVIYNGAHTGSSLE---DFPYGTTV----TYTCNPGPERGVEFSLIGESTIRCTSND 580
Query: 1364 ILR-VWDGPP---ENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS 1418
R W GP + +L + S I G S DT + SGF ++ SS
Sbjct: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSS 640
Query: 1419 SV---ATACRDPGVPM------------NGTRNGDGR---EPGDTVVFQCDPGYELQGEE 1460
+ A DP +P+ +G G G TV + CDPGY L G +
Sbjct: 641 QIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNK 700
Query: 1461 RITCIQVENRYFWQPSPPVCIAPC 1484
I C+ N W PS P C C
Sbjct: 701 SIHCMPSGN---WSPSAPRCEETC 721
Score = 58.9 bits (141), Expect = 9e-08
Identities = 134/619 (21%), Positives = 214/619 (34%), Gaps = 128/619 (20%)
Query: 1096 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1153
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
Query: 1154 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1213
Y N + V G I S H GD + T SM G
Sbjct: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Query: 1214 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1269
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
Query: 1270 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1315
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
Query: 1316 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1372
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
Query: 1373 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1417
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
Query: 1418 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1474
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
Query: 1475 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1530
PS PVC C +G H + N YV+ S+ S
Sbjct: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
Query: 1531 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1584
+ P + + L+ Q + + SS ++ GSV
Sbjct: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
Query: 1585 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1635
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 1636 TCIMGDDGRPGWNRALPSC 1654
C D R W+ P C
Sbjct: 575 RCTSNDQERGTWSGPAPLC 593
Score = 57.8 bits (138), Expect = 2e-07
Identities = 110/479 (22%), Positives = 162/479 (33%), Gaps = 111/479 (23%)
Query: 1077 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1131
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
Query: 1132 RC-VAECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAG--- 1172
C A C + G + P Y L + C+ + Q A
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 1173 ---------------KGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1217
G +I +++ G ++ D + G S T+
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
Query: 1218 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQ--GHFAGSTIIY 1275
S W G +L S C P I + G +S Q + T+I+
Sbjct: 329 SQKTGTW-------SGPAPRCEL---STSAVQCPHPQILR-GRMVSGQKDRYTYNDTVIF 377
Query: 1276 GCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RF-KGESS 1319
C G+TL GS ++C + W+ P C EC RF G S
Sbjct: 378 ACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSI 435
Query: 1320 GRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGPPE 1373
+PGY + +++C +W V + + + T+ H +R P
Sbjct: 436 KYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----PDV 491
Query: 1374 NDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
N + ++SGS+ E TI + + + K C P V
Sbjct: 492 NSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPVIY 534
Query: 1432 NGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCI-QVENRYFWQPSPPVC 1480
NG G E G TV + C+PG + L GE I C + R W P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 48/286 (16%)
Query: 1582 YTGFHLEYKAKLR---------------ESCFDPGNIMNGTRLGMD---YKLGSTVTYYC 1623
Y+GF L+ +++R + C P + +G G + + G TV Y C
Sbjct: 631 YSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTC 690
Query: 1624 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC-------GSRSTGSEGTVLSPNYPK 1676
D GY+L G ++ C+ + W+ + P C C GS +++ +
Sbjct: 691 DPGYLLVGNKSIHCMPSGN----WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQD 746
Query: 1677 NYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH------DVVEVYDGPTQQSSLLSSLSG 1729
Y + GH Y + E ++ + + +H V + G ++ L +
Sbjct: 747 GYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVS 804
Query: 1730 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG-- 1787
+ L ++ R S G + G Q + T+C + PE + G ++
Sbjct: 805 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--PQCLRSPPVTRCPN-PEVKHGYKLNKT 861
Query: 1788 -NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1832
+ ++ V DCNPG+I++GS IRC T W +PTCI
Sbjct: 862 HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGVPTCI 903
Score = 52.4 bits (124), Expect = 8e-06
Identities = 123/519 (23%), Positives = 181/519 (34%), Gaps = 101/519 (19%)
Query: 177 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 235 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-TDFQME-EKY 292
C + P P Y + GD+++ T+F M K
Sbjct: 82 CEYFNKYSS--------CPEPIVPGGYKIRGSTPY----RHGDSVTFACKTNFSMNGNKS 129
Query: 293 DYLEIEGSEPPTIWLSGMNIPP------PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKK 346
+ + PT + +++ P P+I N + H + G S Y +
Sbjct: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGH----HTSENVGSIAPGLSVTYSCES 185
Query: 347 AIDFKSRGFKLFPGKD----NSNKFSILNEGGIKTASNLCPDPGEPENGK-RIGSDFSLG 401
G+ L K +S K+S + C G NGK + +G
Sbjct: 186 -------GYLLVGEKIINCLSSGKWSAVPP---TCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
T F CDE Y LQG S C IA AW+ PVC+ C S +G +
Sbjct: 236 VTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSL- 292
Query: 462 FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTLTIG-DGGEVGD-----PRTVL 514
+N ++T + + +NF + IG TL D + G PR L
Sbjct: 293 ----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
Query: 515 ----------QVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPG 564
Q+L G V S Q + D + + F K ++ C G
Sbjct: 345 STSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQG 397
Query: 565 T--PLYGIREGD----------GFSNRDVLRFE--------CQFGFELIGEKSIVCQENN 604
T P + E + +R ++RF+ C G+ L+GE+SI C
Sbjct: 398 TWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
Query: 605 QWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 638
W+ +P C + C + T P + PD G
Sbjct: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
Score = 51.2 bits (121), Expect = 2e-05
Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 59/252 (23%)
Query: 906 CLDPGIPVHGRRYG---HDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHW-WSHPLPT 958
C P + V+G+ G +F G+ VS+ CD G+ L E+ L C K H WS P P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 959 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1018
C +R P T PN +V HG + T H+D +
Sbjct: 838 C-------LRSPPVTRC--------PNP-------EVKHGYKLN---KTHSAYSHNDIVY 872
Query: 1019 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1078
+ N F +R+ T G+ + FI C
Sbjct: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKA--FIG--------------------C 910
Query: 1079 EDPGIPQYGSRIGFN---FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1135
P G+ G N F G ++ +SC GY L G + ++C G WS P P C
Sbjct: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHCKE 968
Query: 1136 ECGASATNNEGI 1147
+S + +GI
Sbjct: 969 VNCSSPADMDGI 980
Score = 49.7 bits (117), Expect = 5e-05
Identities = 107/501 (21%), Positives = 171/501 (34%), Gaps = 122/501 (24%)
Query: 193 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII 252
RFD G I+YSC GY+L G + C + V W PVP C+ AC T R ++
Sbjct: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGV----WTPPVPQCKVA-ACEATGRQ---LL 479
Query: 253 SSPSFPNEYHN-NADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMN 311
+ P + N+ C G+ L + +Q E +G+ P W +
Sbjct: 480 TKPQHQFVRPDVNSSC--------GEGYKLSGSVYQ--------ECQGTIP---WFMEIR 520
Query: 312 I-------PPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNS 364
+ PPP+I N H + G + Y PG +
Sbjct: 521 LCKEITCPPPPVIYNG----AHTGSSLEDFPYGTTVTYTCN-------------PGPERG 563
Query: 365 NKFSILNEGGIKTASN------------LCP--------DPGEPENGKRIG---SDFSLG 401
+FS++ E I+ SN LC NG +I + +
Sbjct: 564 VEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYN 623
Query: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
TV F C + L+G+ I C+ W PV C Q P P
Sbjct: 624 DTVTFKCYSGFTLKGSSQIRCK----ADNTWDPEIPV-----CEKGCQSP------PGLH 668
Query: 462 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDP----------- 510
+ V+ ++ + + + L +G ++ G
Sbjct: 669 HGRHTGGNTVFFVSGMTVDYTCDPGY----LLVGNKSIHCMPSGNWSPSAPRCEETCQHV 724
Query: 511 RTVLQVL-TGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEI---EKESCGDPGTP 566
R LQ L GS V + S L + + +K+I + C P
Sbjct: 725 RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVI 784
Query: 567 LYGIREG---DGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANIPICIFPCLS 619
+ G G + F + + +EC GF L+GEK + C+ +++ WS P C+
Sbjct: 785 VNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL----- 839
Query: 620 NFTAPMGTVLSPDYPEGYGNN 640
+ P+ +P+ GY N
Sbjct: 840 -RSPPVTRCPNPEVKHGYKLN 859
Score = 49.3 bits (116), Expect = 7e-05
Identities = 91/414 (21%), Positives = 146/414 (35%), Gaps = 88/414 (21%)
Query: 571 REGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLS 630
+E F N D + F+C GF L G I C+ +N W IP+ C +P G
Sbjct: 616 KEAPYFYN-DTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV----CEKGCQSPPGL--- 667
Query: 631 PDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFT 688
+ G N T+ G + + + + L + G+ SP +P T
Sbjct: 668 -HHGRHTGGN-----TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-T 720
Query: 689 GAEVPSHLT-----SNSHILRLEFQADHSMSGRGFNITYNTFGHN-----------ECPD 732
V L S ++ Q + ++G + + + C
Sbjct: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
Query: 733 PGIPINARRFG---DNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCG 788
P + +N + G +NF G+ +S C++GF G + + C G WSG P+C
Sbjct: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCL 839
Query: 789 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 848
S P +P E + G+ + T + + D++ V
Sbjct: 840 R------SPPVTRCPNP----------------EVKHGYKLNKTHSAYS---HNDIVYVD 874
Query: 849 DGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLD 908
P + NG++V + TDN+ G + + C
Sbjct: 875 CNPGFIM------NGSRV------------IRCHTDNTWVP-GVPTCIKKAFIG---CPP 912
Query: 909 PGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
P +G G + FS G ++ +SCD GY L E LLC WS P P C
Sbjct: 913 PPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966
Score = 45.1 bits (105), Expect = 0.001
Identities = 56/247 (22%), Positives = 85/247 (34%), Gaps = 78/247 (31%)
Query: 908 DPGIPV------------HGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 952
DP IPV HGR G + F G TV ++CD GY L + + C + W
Sbjct: 651 DPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNW 710
Query: 953 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL-E 1011
S P C+ C VR + + E V+ + G Q H + + +
Sbjct: 711 SPSAPRCEETC-QHVRQSLQELPAGSRVEL----------VNTSCQDGYQLTGHAYQMCQ 759
Query: 1012 DHHDYLLITENGSFTQ--PLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNIT 1069
D ENG + + PL ++ PP I G + A+
Sbjct: 760 D-------AENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE----------------- 795
Query: 1070 FSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG--GRRVWS 1127
NF G+ +++ C G+ L G ++ C G WS
Sbjct: 796 -----------------------NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 832
Query: 1128 APLPRCV 1134
P P+C+
Sbjct: 833 GPSPQCL 839
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 375 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 431
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 903 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 958
Query: 432 WSDHRPVCKVKTCGS 446
WS P CK C S
Sbjct: 959 WSQPAPHCKEVNCSS 973
Score = 44.7 bits (104), Expect = 0.002
Identities = 187/872 (21%), Positives = 282/872 (32%), Gaps = 178/872 (20%)
Query: 729 ECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 785
ECP + N +N G S++ CE G++ G + I C L GK WS + P
Sbjct: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPP 208
Query: 786 KCG-APCGGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSI 829
C A C P+G + P G+ S C + +
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 830 KITFERFQTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLF 881
+ E F + H G +L + GS Y P+ NFI L
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRC 325
Query: 882 TTDNSRSN--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGY 936
T D+ ++ +G E ++ + C P I + GR ++ TV F+C G+
Sbjct: 326 TVDSQKTGTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 937 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGY 979
L + + C W P C+ C VR GT + +PGY
Sbjct: 384 TLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 980 PEFYPNSLNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT 1033
S+ CT WT V K + + H ++ N S + +L+
Sbjct: 444 VLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLS 502
Query: 1034 GSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF- 1092
GS +Y + + + + + E IT C P + G+ G
Sbjct: 503 GS---------VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSS 542
Query: 1093 --NFGIGDTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAEC 1137
+F G T+T++C+ G + L G S I C R WS P P C +C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 1138 GASATNNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDG 1195
N + P Y + +C ++ I A + V +
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
Query: 1196 KDKTTHLLGAFTGAS----MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1251
H G TG + + G+T+ T D G+ LV + HC
Sbjct: 663 SPPGLH-HGRHTGGNTVFFVSGMTVDYT--------------CDPGYLLV--GNKSIHCM 705
Query: 1252 -----DPGIPQF-----GYKISDQGHFAGSTIIY---GCNPGYTLHGSSLLKCMTGERRA 1298
P P+ + S Q AGS + C GY L G + C E
Sbjct: 706 PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGI 765
Query: 1299 WDYPLPSC-IAECGGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFL 1354
W +P C + C G+ +G + F Y N + E D G L
Sbjct: 766 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAE---NFLYGNEV----SYECDQG-FYLLGEK 817
Query: 1355 AFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHS-TLNIVTIQFDTD--FYISKSG 1411
+ W GP + ++ PE H LN + + Y+ +
Sbjct: 818 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNP 877
Query: 1412 FAIQFSSSVATACRD----PGVPM----------------NGTRNGDG---REPGDTVVF 1448
I S V D PGVP NG G PG ++++
Sbjct: 878 GFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILY 937
Query: 1449 QCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
CD GY L GE + C + W P C
Sbjct: 938 SCDQGYLLVGEALLLC---THEGTWSQPAPHC 966
Score = 43.5 bits (101), Expect = 0.004
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 2120 CPDPRPFRNGFVIGND---FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
CP P NG G + F+ G +I + C GY L+G + L C H W+ P P C+
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH--EGTWSQPAPHCK 967
Query: 2177 ALCGGNITAMNG 2188
+ + M+G
Sbjct: 968 EVNCSSPADMDG 979
Score = 42.4 bits (98), Expect = 0.008
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 382 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 438
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 439 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 497
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 838 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 885
Query: 498 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 545
+ G P + + G P I S M + D+
Sbjct: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 945
Query: 546 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 591
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 946 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 1005
Query: 592 LIGEKSIVCQENNQWSANIPIC 613
L G CQ ++QW+ + +C
Sbjct: 1006 LEGSPQSQCQSDHQWNPPLAVC 1027
Score = 40.8 bits (94), Expect = 0.024
Identities = 66/299 (22%), Positives = 113/299 (37%), Gaps = 72/299 (24%)
Query: 176 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASW-DFPVP 233
SSC P VP + G T + GD + ++C T + ++G+ + C AN++ W +P
Sbjct: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM----WGPTRLP 144
Query: 234 ICRAEDACGGTMRGSSGIISSPSFP--NEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK 291
C S + P+ P + H+ ++ +I T S + EK
Sbjct: 145 TC-----------VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 292 YDYLEIEG---SEPPTI----------WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGF 338
G + PPT + +G PPI+ + + +F D +R +G
Sbjct: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL--RVGVTANFFCDEGYRLQG- 250
Query: 339 SAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLC-----PDPGEPENGKR 393
S++ I +G T +C P P NG+
Sbjct: 251 -----------------------PPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRH 287
Query: 394 IG---SDFSLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAWSDHRPVCKVKT 443
IG ++ S GS V ++CD D ++L G ++ C ++ WS P C++ T
Sbjct: 288 IGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELST 346
Score = 40.4 bits (93), Expect = 0.031
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 2119 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCL--HGVSRNWNHPLPR 2174
SC P P NG + VG I + C + LIG +L C+ V W+ P P+
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 2175 CE 2176
CE
Sbjct: 82 CE 83
Score = 38.9 bits (89), Expect = 0.091
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 1596 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1653
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1654 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1700
C P G + G S Y SV C + ++ V+ Q
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 1701 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1759
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
Query: 1760 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1810
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
Query: 1811 AIRCETVPNSLAQWNDSLPTC 1831
+ RC +A W +P C
Sbjct: 253 SSRCVIAGQGVA-WT-KMPVC 271
Score = 37.0 bits (84), Expect = 0.35
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 1949 PEPQTPSSGIKIGD--RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2006
P P+TP+ G+ R+ G + + CDQGY L G + + C W+ P P C
Sbjct: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT--WSQPAPHCKEV 969
Query: 2007 CGGAMSDFSGV 2017
+ +D G+
Sbjct: 970 NCSSPADMDGI 980
Score = 36.2 bits (82), Expect = 0.59
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 1957 GIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
G++ Y G VV+ +C+ GY L+G C +WN P+ +C
Sbjct: 983 GLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSD--HQWNPPLAVC 1027
Score = 35.8 bits (81), Expect = 0.77
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 905 SCLDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPT 958
SC P ++GR Y ++G+ + +SC +RL E+ LLC + + W P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 959 CD 960
C+
Sbjct: 82 CE 83
Score = 35.8 bits (81), Expect = 0.77
Identities = 56/279 (20%), Positives = 105/279 (37%), Gaps = 63/279 (22%)
Query: 1070 FSEYNLEPCEDPGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS- 1127
F++Y+ C +P +P Y R + GD++TF+C + + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGP 140
Query: 1128 APLPRCVA----ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1183
LP CV+ EC P P+ + +H + G + S + +
Sbjct: 141 TRLPTCVSVFPLEC-------------PALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
Query: 1184 LAQGD--VLKIYDGK---------DKTTHLLGAFTGASMR-------GLTLSSTSNQLW- 1224
L G+ + + GK + LG F ++ G+T + ++ +
Sbjct: 188 LLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247
Query: 1225 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP---------QFGYKISDQGHFAGSTIIY 1275
L+ + G + +T + CE+ P G +++ + GS + Y
Sbjct: 248 LQGPPSSRCVIAGQGVAWTKMPV--CEEIFCPSPPPILNGRHIGNSLANVSY--GSIVTY 303
Query: 1276 GCNP------GYTLHGSSLLKCMTGERR--AWDYPLPSC 1306
C+P + L G S L+C ++ W P P C
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342
Score = 35.8 bits (81), Expect = 0.77
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 178 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 965
Query: 235 CR 236
C+
Sbjct: 966 CK 967
Score = 35.8 bits (81), Expect = 0.77
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 964
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 990 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
Score = 33.1 bits (74), Expect = 5.0
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 171 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 1022
Query: 231 PVPICRA 237
P+ +CR+
Sbjct: 1023 PLAVCRS 1029
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 315 bits (806), Expect = 7e-85
Identities = 257/918 (27%), Positives = 392/918 (42%), Gaps = 116/918 (12%)
Query: 2465 CSTPESPPHGYI-ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2523
C +P +G I T + +V+R++C FRL+G+ S +C WD P P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2524 QAI----SCGIPKAPTNGGIL-TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2578
+ SC P P I +T Y G VT+ C + ++ + + CQ++ W
Sbjct: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK--SVWCQANNMW-G 139
Query: 2579 HNKTPRCVVI---SCGELPTPPNGNKIGTQTSYGSTA-----IFTCDLGFMLVGSAVREC 2630
+ P CV + C LP NG+ T + GS A ++C+ G++LVG + C
Sbjct: 140 PTRLPTCVSVFPLECPALPMIHNGHH--TSENVGSIAPGLSVTYSCESGYLLVGEKIINC 197
Query: 2631 LSSGLWSESETRCLAGHCGIPELIVNGQV-------IGENYGYRDTVVYQCNPGFRLIG- 2682
LSSG WS C C NG+V +G T + C+ G+RL G
Sbjct: 198 LSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV------TANFFCDEGYRLQGP 251
Query: 2683 --SSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGF---NFNDVVTFSCN---- 2733
S I Q W+ ++P C + C P + GR GN ++ +VT++C+
Sbjct: 252 PSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
Query: 2734 --IGYLMQGPTKAQCQANRQ----WSHPPPMCKV----VNCSDPGIPANSKRESKIEHGN 2783
+ +++ G + +C + Q WS P P C++ V C P I R +
Sbjct: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRG--RMVSGQKDR 368
Query: 2784 FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK-- 2841
+TY V + C G+ L GS + C G W+ P C +C PPN +L+G+K
Sbjct: 369 YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC---QAPPN-ILNGQKED 423
Query: 2842 -----YTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG 2896
+ G+++ YSC L+G+ S C G W+ P C A G
Sbjct: 424 RHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLL---- 479
Query: 2897 SRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANG-- 2954
++ + F + V +C GY L GS + C W CK + C P NG
Sbjct: 480 TKPQHQF-VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAH 538
Query: 2955 KVFRIDGTTFSSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLPNCTI--- 3001
++ + ++V Y+C G + L G S +CT+N GTWSG P C +
Sbjct: 539 TGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL 598
Query: 3002 -ISCGDPGIPANGLRYGD---DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3057
+ C I ANG + Y V++ C G+T L GS C + TW +P
Sbjct: 599 AVQCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYSGFT--LKGSSQIRCKADNTWDPEIP 655
Query: 3058 TCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTC--VGNGTWSGEVP 3115
C TC Q G+ + ++ C GY+L+ A C NG W ++P
Sbjct: 656 VCEKETCQHVRQSLQELPAGSRVE---LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 3116 QCLPKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQAD----GTW 3168
C C P + GK G ++F+Y +EVS+ C+ F L+G C++D G+W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 3169 SGSSPHCI-EPTQTSCENPGVPRHGSQNNT--FGFQVGSVVQFHCKKGHLLQGSTTRTCL 3225
SG SP C+ P T C NP V +HG + N + +V C G ++ GS C
Sbjct: 773 SGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 831
Query: 3226 PDLTWSGIQPECIPHS---CKQPETPAHANVVGMDLP--SHGYTLIYTCQPGFFLAGGTE 3280
D TW P CI + C P + N G ++ S G +++Y+C G+ L G
Sbjct: 832 TDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEA 890
Query: 3281 HRVCRSDNTWTGKVPICE 3298
+C + TW+ P C+
Sbjct: 891 LLLCTHEGTWSQPAPHCK 908
Score = 308 bits (788), Expect = 8e-83
Identities = 269/927 (29%), Positives = 387/927 (41%), Gaps = 107/927 (11%)
Query: 2452 NKKGFRIRYIAFYCSTPES-PPHGYII-SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKS 2509
+K + Y Y S PE P GY I T + V +AC F + G S C+ +
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 2510 SYGYHAWDAP-VPACQAI-SCGIPKAPT-NGGILTTDYL----VGTRVTYFCNDGYRLSS 2562
+ W +P C ++ P P + G T++ + G VTY C GY L
Sbjct: 136 NM----WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 2563 KELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFM 2621
+++ C S G WS P C C L PNG K G TA F CD G+
Sbjct: 192 EKIIN--CLSSGKWSA--VPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247
Query: 2622 LVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQVIGE---NYGYRDTVVYQCN 2675
L G C+ +G W++ C C P I+NG+ IG N Y V Y C+
Sbjct: 248 LQGPPSSRCVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCD 306
Query: 2676 P------GFRLIGSSVRIC----QQDHNWSGQLPSCV----PVSCGHP----GSPIYGRT 2717
P F LIG S C Q+ WSG P C V C HP G + G+
Sbjct: 307 PDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQK 366
Query: 2718 SGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRES 2777
+ + +ND V F+C G+ ++G + +C A W P+C+ C P N ++E
Sbjct: 367 --DRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKED 423
Query: 2778 KIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVL 2837
+ F GT + Y CNPGY L G + C G W P+P+C + C G +L
Sbjct: 424 R-HMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG---RQLL 479
Query: 2838 SGEKYTF-GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG 2896
+ ++ F V+ SC L G + CQ W C TC P +G
Sbjct: 480 TKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI---TCPPPPVIYNG 536
Query: 2897 SRQESN---FRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECK-- 2941
+ S+ F +TV Y C+ G + L G C +N G+W+G P CK
Sbjct: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLS 596
Query: 2942 --AVQCGNPGTTANGKVFRIDGTT----FSSSVIYSCMEGYILSGPSVRQCTANGTWSGT 2995
AVQC + ANG ++I G ++ +V + C G+ L G S +C A+ TW
Sbjct: 597 LLAVQCSHVHI-ANG--YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 2996 LPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTC--TINGTWS 3053
+P C +C L G + V+ CQ GY +L G + C NG W
Sbjct: 654 IPVCEKETCQHVRQSLQELPAGSRVEL---VNTSCQDGY--QLTGHAYQMCQDAENGIWF 708
Query: 3054 GVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPGYELSFPAVLTC----VG 3106
+P C+ + C PP I NG+ G NF +G +SY C G+ L L C G
Sbjct: 709 KKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKG 768
Query: 3107 NGTWSGEVPQCLPK----FCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFILVGSSTR 3160
+G+WSG PQCL C +P + K + ++ + V CN FI+ GS
Sbjct: 769 HGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVI 828
Query: 3161 ICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFG----FQVGSVVQFHCKKGHLL 3216
C D TW P CI+ C P P+ + N+T G F G + + C +G+LL
Sbjct: 829 RCHTDNTWVPGVPTCIKKAFIGCPPP--PKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 886
Query: 3217 QGSTTRTCLPDLTWSGIQPECIPHSCKQPE--TPAHANVVGMDLPSHGYTLIYTCQPGFF 3274
G C + TWS P C +C P + + +G + C+ G+
Sbjct: 887 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 946
Query: 3275 LAGGTEHRVCRSDNTWTGKVPICEAGS 3301
L G + + C+SD+ W + +C + S
Sbjct: 947 LEGSPQSQ-CQSDHQWNPPLAVCRSRS 972
Score = 264 bits (675), Expect = 1e-69
Identities = 232/790 (29%), Positives = 335/790 (42%), Gaps = 101/790 (12%)
Query: 2583 PRCVVISCGELPTPPNG--NKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS----GLW 2636
P + ISCG P NG + T + G+ ++C F L+G C++ G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 2637 SESETRC--LAGHCGIPELIVNG--QVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQD 2691
+ +C + PE IV G ++ G Y + D+V + C F + G+ CQ +
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 2692 HNWSG-QLPSCV---PVSCGHPGSPIYGRTSGNGFNFNDV-----VTFSCNIGYLMQGPT 2742
+ W +LP+CV P+ C P P+ N + VT+SC GYL+ G
Sbjct: 136 NMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 2743 KAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG 2802
C ++ +WS PP C+ C G N K + E G + C+ GY L G
Sbjct: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVK---EPPILRVGVTANFFCDEGYRLQG 250
Query: 2803 SSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGE-------KYTFGSTVHYSC 2852
C GQ W K +P C I C P PP +L+G ++GS V Y+C
Sbjct: 251 PPSSRCVIAGQGVAWTK-MPVCEEIFC--PSPPP--ILNGRHIGNSLANVSYGSIVTYTC 305
Query: 2853 TGKRS------LLGQSSRTC----QLNGHWSGSQPHCSGDATGT-CGDPG--TPGHGSRQ 2899
L+G+S+ C Q G WSG P C + C P S Q
Sbjct: 306 DPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQ 365
Query: 2900 ESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGK---- 2955
+ + TV +AC G+ L GS++ C A G+W P C+ +C P NG+
Sbjct: 366 KDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDR 424
Query: 2956 -VFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGL 3014
+ R D T S+ YSC GY+L G QCT+ G W+ +P C + +C G L
Sbjct: 425 HMVRFDPGT---SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG--RQLL 479
Query: 3015 RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGR 3074
V +V+ C GY +L+GS + C W + C+ +TCP PP I NG
Sbjct: 480 TKPQHQFVRPDVNSSCGEGY--KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGA 537
Query: 3075 LEGT---NFDWGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQC---- 3117
G+ +F +G +++Y C+PG + L + + C N GTWSG P C
Sbjct: 538 HTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSL 597
Query: 3118 LPKFCGDPGIPAQGKREGKS--FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3175
L C I K GK + Y V+F C F L GSS C+AD TW P C
Sbjct: 598 LAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC 657
Query: 3176 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTC--LPDLTWSGI 3233
+ T C++ R Q G +V +V C+ G+ L G + C + W
Sbjct: 658 EKET---CQH---VRQSLQELPAGSRV-ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKK 710
Query: 3234 QPECIPHSCKQPETPAHANVVGMDLPS--HGYTLIYTCQPGFFLAGGTEHRVCRSDN--- 3288
P C C P + GM + +G + Y C GF+L G + + CRSD+
Sbjct: 711 IPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQ-CRSDSKGH 769
Query: 3289 -TWTGKVPIC 3297
+W+G P C
Sbjct: 770 GSWSGPSPQC 779
Score = 179 bits (453), Expect = 6e-44
Identities = 136/506 (26%), Positives = 210/506 (41%), Gaps = 64/506 (12%)
Query: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG---GILTTDY 2544
V +C G++L G C+ G W + C+ I+C P NG G D+
Sbjct: 491 VNSSCGEGYKLSGSVYQECQ----GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
Query: 2545 LVGTRVTYFCNDG----YRLSSKELTTAVCQSD----GTWSNHNKTPRC----VVISCGE 2592
GT VTY CN G S +T C S+ GTWS P C + + C
Sbjct: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG--PAPLCKLSLLAVQCSH 604
Query: 2593 LPTPPNGNKIGTQTS---YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHC- 2648
+ NG KI + + Y T F C GF L GS+ C + W C C
Sbjct: 605 VHIA-NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ 663
Query: 2649 ----GIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHN--WSGQLPSCV 2702
+ EL +V + V C G++L G + ++CQ N W ++P C
Sbjct: 664 HVRQSLQELPAGSRV--------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 715
Query: 2703 PVSCGHPGSPIYGRTSG---NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ----WSHP 2755
+ C P + G+ +G F + + V++ C+ G+ + G K QC+++ + WS P
Sbjct: 716 VIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 775
Query: 2756 PPMC----KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2811
P C V C +P + K H +++ +V+ DCNPG+ + GS V+ C +
Sbjct: 776 SPQCLRSPPVTRCPNPEVKHGYKLNKT--HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTD 833
Query: 2812 GQWDKPLPECI---MIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQSSRT 2865
W +P CI I C P PN +G +++ G ++ YSC L+G++
Sbjct: 834 NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL 893
Query: 2866 CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEER 2925
C G WS PHC + D G ++ + V C+ GY+L GS +
Sbjct: 894 CTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS 953
Query: 2926 TCLANGSWTGRQPECKA-----VQCG 2946
C ++ W C++ V CG
Sbjct: 954 QCQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 142 bits (359), Expect = 4e-33
Identities = 239/1050 (22%), Positives = 371/1050 (35%), Gaps = 183/1050 (17%)
Query: 1761 FVYQAVPRTSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1818
F+ P C S P GR AVG+ + + C+ + L G ++ C T
Sbjct: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
Query: 1819 NSLAQWNDSLPTC------------IVPCG----GILTKRKGTILSPGYPEPYDNNLN-C 1861
W+ P C IVP G G R G ++ + N N
Sbjct: 70 KVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKS 129
Query: 1862 VWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYS-GTTIPHLLNSTSNN 1920
VW ++ +L G + + +GS + G ++ + S +
Sbjct: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTY---SCESG 186
Query: 1921 LYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSG------IKIGDRYMVGDVVSFQC 1974
L + I+ ++G +++A+ +C E + S G +K VG +F C
Sbjct: 187 YLLVGEKIINCLSSG---KWSAVP-PTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFC 242
Query: 1975 DQGYSLQGHSHITCM-PGPVRRWNYPIPICLAQ-CGGAMSDFSGVILSPGFPGNYPSSLD 2032
D+GY LQG C+ G W +P+C C +G + S+
Sbjct: 243 DEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI- 300
Query: 2033 CTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHE 2092
T+T + GV+ + ST L S +T T SGP P ST+
Sbjct: 301 VTYTCDPDPEEGVNFILIGEST------LRCTVDSQKTGT----WSGPA-PRCELSTS-- 347
Query: 2093 TSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND--FTVGQTISFECFPGY 2150
CP P+ R V G +T T+ F C G+
Sbjct: 348 ------------------------AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 2151 TLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNG-------TIYSPGYPDEY---P 2200
TL G+ + C W P CE C +NG + PG +Y P
Sbjct: 384 TLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 2201 NF-----------QDCFWLVRVPPGNGIYINFT--VLQTEPIYDFITVWDGPDQNSPQIG 2247
+ + W VP T L T+P + F+ PD NS G
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----PDVNS-SCG 496
Query: 2248 QFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQ----PPPPV--PNAE 2301
+ G SVY + F ++R+C+ PPPPV A
Sbjct: 497 E--GYKLSGSVYQECQGTIPWF----------------MEIRLCKEITCPPPPVIYNGAH 538
Query: 2302 ILTEDDEFEIGDIIRYQCLPG------FTLVGNAILTCRLG--ERLQMDGAPPVCQVLCP 2353
+ ++F G + Y C PG F+L+G + + C ER G P+C++
Sbjct: 539 TGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL--- 595
Query: 2354 ANELRLDSTGVILSPGYPDS--------YPNLQMCAWSISVEKGYNITMFVEFFQTEKEF 2405
+ L + + V ++ GY S + +S KG + + E
Sbjct: 596 -SLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEI 654
Query: 2406 DVLQVYDGPNIQSPVLISLSGDYSSAFNITS------NGHEVFLQWSADHGNNKKGFRIR 2459
V + +++ + +G N + GH + A++G K +
Sbjct: 655 PVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 714
Query: 2460 YIAFYCSTPESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2517
+ +C P +G + V + CD+GF L+G+ CR S G+ +W
Sbjct: 715 KV-IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773
Query: 2518 APVPAC----QAISCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQ 2571
P P C C P+ + T Y V CN G+ ++ + C
Sbjct: 774 GPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIR--CH 831
Query: 2572 SDGTWSNHNKTPRCV---VISCGELPTPPNGNKIG---TQTSYGSTAIFTCDLGFMLVGS 2625
+D TW P C+ I C P PNGN G + S G + +++CD G++LVG
Sbjct: 832 TDNTWV--PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGE 889
Query: 2626 AVRECLSSGLWSESETRCLAGHCGIP---ELIVNGQVIGENYGYRDTVVYQCNPGFRLIG 2682
A+ C G WS+ C +C P + I G + Y Y V +C G+ L G
Sbjct: 890 ALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEG 949
Query: 2683 SSVRICQQDHNWSGQLPSC-----VPVSCG 2707
S CQ DH W+ L C PV CG
Sbjct: 950 SPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 99.0 bits (245), Expect = 7e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 3055 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3108
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 3109 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3163
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 3164 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3218
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 3219 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3278
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 3279 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3312
R + WT K+P+CE +I P P L
Sbjct: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
Score = 81.6 bits (200), Expect = 1e-14
Identities = 193/878 (21%), Positives = 300/878 (34%), Gaps = 183/878 (20%)
Query: 1077 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1131
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
Query: 1132 RCV-AECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAGKGI 1175
C A C + G + P Y L + C+ + Q A +
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 1176 NISARTF------------------HLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1217
+ F +++ G ++ D + G S T+
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
Query: 1218 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQG--HFAGSTI 1273
S W G +L ++ + H PQ G +S Q + T+
Sbjct: 329 SQKTGTW-------SGPAPRCELSTSAVQCPH------PQILRGRMVSGQKDRYTYNDTV 375
Query: 1274 IYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RFK-GE 1317
I+ C G+TL GS ++C + W+ P C EC RF G
Sbjct: 376 IFACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGT 433
Query: 1318 SSGRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGP 1371
S +PGY + +++C +W V + + + T+ H +R P
Sbjct: 434 SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----P 489
Query: 1372 PENDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGV 1429
N + ++SGS+ E TI + + + K C P V
Sbjct: 490 DVNSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPV 532
Query: 1430 PMNGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCIQVEN-RYFWQPSPPV 1479
NG G E G TV + C+PG + L GE I C + R W P+
Sbjct: 533 IYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPL 592
Query: 1480 C----IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1535
C +A ++ ++G+ +S PY ++ D V + F+++ +
Sbjct: 593 CKLSLLAVQCSHVHIANGYKISGK-EAPYFYN-----------DTVTFKCYSGFTLKGSS 640
Query: 1536 DFLYIYDGP-DSNSPLIG---------SFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1585
D D P+ S Q+ R+E + + ++ G
Sbjct: 641 QIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQ 700
Query: 1586 HLEYKAKLRE-------SCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAGYVLQGYSTL 1635
E ++ C P I+NG GM ++ G+ V+Y CD G+ L G L
Sbjct: 701 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 760
Query: 1636 TCIMGDDGRPGWNRALPSC-HAPCGSRSTGSEGTVLSPNYPKN---YSVGHNCVYSIAVP 1691
C G W+ P C +P +R E + Y N + HN + +
Sbjct: 761 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE---VKHGYKLNKTHSAYSHNDIVYVDCN 817
Query: 1692 KEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLL-------SSLSGSHSGESLP-LSSGNQ 1743
F++ G V D V PT + +G+H+G ++ S G
Sbjct: 818 PGFIMNGSRVI--RCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMS 875
Query: 1744 ITIR----FTSVGPITAKGFH--FVYQAVPRTSSTQCSSVPEPRFGRRIGNE----FAVG 1793
I + VG H Q P CSS P G + G E + G
Sbjct: 876 ILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYG 934
Query: 1794 SSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
+ V +C GY+L GS +C+ S QWN L C
Sbjct: 935 AVVTLECEDGYMLEGSPQSQCQ----SDHQWNPPLAVC 968
Score = 68.6 bits (166), Expect = 1e-10
Identities = 170/817 (20%), Positives = 277/817 (33%), Gaps = 159/817 (19%)
Query: 1096 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1153
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
Query: 1154 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1213
Y N + V G I S H GD + T SM G
Sbjct: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Query: 1214 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1269
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
Query: 1270 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1315
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
Query: 1316 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1372
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
Query: 1373 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1417
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
Query: 1418 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1474
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
Query: 1475 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1530
PS PVC C +G H + N YV+ S+ S
Sbjct: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
Query: 1531 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1584
+ P + + L+ Q + + SS ++ GSV
Sbjct: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
Query: 1585 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1635
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 1636 TCIMGDDGRPGWNRALPSC------------HAPCGSRSTGSEGTVLSPNYPKNYSVGHN 1683
C D R W+ P C H G + +G E Y N +V
Sbjct: 575 RCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP-----YFYNDTVTFK 629
Query: 1684 CVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPL----- 1738
C + + + + + V + T Q + SL +G + L
Sbjct: 630 CYSGFTLKGSSQIRCK---ADNTWDPEIPVCEKETCQ-HVRQSLQELPAGSRVELVNTSC 685
Query: 1739 SSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSS 1795
G Q+T + G F + +P C P G+ G F G+
Sbjct: 686 QDGYQLTGHAYQMCQDAENGIWF--KKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 743
Query: 1796 VLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1832
V ++C+ G+ L G ++C + W+ P C+
Sbjct: 744 VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 780
Score = 62.8 bits (151), Expect = 6e-09
Identities = 102/447 (22%), Positives = 162/447 (36%), Gaps = 79/447 (17%)
Query: 1614 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1672
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
Query: 1673 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1728
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
Query: 1729 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1773
+ L + SG + T+ F + T KG + ++ +
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
Query: 1774 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
Query: 1831 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1865
C + C +LTK + + P Y E P+ + +I
Sbjct: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
Query: 1866 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 1919
T P V + H SL+ + G N P G + TSN
Sbjct: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
Query: 1920 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 1976
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 1977 GYSLQGHSHITCMPGPVRRWNYPIPIC 2003
G++L+G S I C W+ IP+C
Sbjct: 633 GFTLKGSSQIRCKAD--NTWDPEIPVC 657
Score = 60.1 bits (144), Expect = 4e-08
Identities = 186/922 (20%), Positives = 311/922 (33%), Gaps = 241/922 (26%)
Query: 176 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASW-DFPVP 233
SSC P VP + G T + GD + ++C T + ++G+ + C AN++ W +P
Sbjct: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM----WGPTRLP 144
Query: 234 ICRAEDACGGTMRGSSGIISSPSFP--NEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK 291
C S + P+ P + H+ ++ +I T S + EK
Sbjct: 145 TC-----------VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 292 YDYLEIEG---SEPPTI----------WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGF 338
G + PPT + +G PPI+ + + +F D +R +G
Sbjct: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL--RVGVTANFFCDEGYRLQG- 250
Query: 339 SAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLC-----PDPGEPENGKR 393
S++ I +G T +C P P NG+
Sbjct: 251 -----------------------PPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRH 287
Query: 394 IG---SDFSLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
IG ++ S GS V ++CD D ++L G ++ C ++ WS P C++ T
Sbjct: 288 IGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTS 347
Query: 445 -----------GSNLQGPSGTFTSPN-------FPF------QYDSNAQCVWVITAVNTN 480
G + G +T + F F Q NAQ W +A
Sbjct: 348 AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE 407
Query: 481 KVIQ-----INFEEFD--------------------LEIGYDTLTIGDGGEVGDPRTVLQ 515
K Q +N ++ D + +G +++ G P +
Sbjct: 408 KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 516 VLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN---YKEIE------------KE-S 559
V +++ ++ + S G G+K++ Y+E + KE +
Sbjct: 468 VAACEATGRQLLTKPQHQFVRPDVNSSCGE-GYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 560 CGDPGTPLYGIREG---DGFSNRDVLRFECQFG------FELIGEKSIVCQENNQ----W 606
C P G G + F + + C G F LIGE +I C N+Q W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 607 SANIPIC-----IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFND 661
S P+C C A + + P Y + + ++
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVT-------------FKCYSG 633
Query: 662 FDLESQFDFLAVKDGD-SPESPILGTFTGAEVPSHLT-----SNSHILRLEFQADHSMSG 715
F L+ D PE P+ T V L S ++ Q + ++G
Sbjct: 634 FTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 693
Query: 716 RGFNITYNTFGH-----------NECPDPGIPINARRFG---DNFQLGSSISVICEEGFI 761
+ + + C P + +N + G +NF G+ +S C++GF
Sbjct: 694 HAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY 753
Query: 762 KTQGTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWV 820
G + + C G WSG P+C S P +P
Sbjct: 754 -LLGEKKLQCRSDSKGHGSWSGPSPQCLR------SPPVTRCPNP--------------- 791
Query: 821 IEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLL 880
E + G+ + T + + D++ V P + NG++V +
Sbjct: 792 -EVKHGYKLNKTHSAYS---HNDIVYVDCNPGFI------MNGSRV------------IR 829
Query: 881 FTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYR 937
TDN+ G + + C P +G G + FS G ++ +SCD GY
Sbjct: 830 CHTDNTWV-PGVPTCIKKAFI---GCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 885
Query: 938 LSHEEPLLCEKNHWWSHPLPTC 959
L E LLC WS P P C
Sbjct: 886 LVGEALLLCTHEGTWSQPAPHC 907
Score = 59.3 bits (142), Expect = 7e-08
Identities = 188/892 (21%), Positives = 295/892 (33%), Gaps = 257/892 (28%)
Query: 925 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 977
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 978 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1028
GY P S C V G+GV + + + E P
Sbjct: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
Query: 1029 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1088
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
Query: 1089 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1148
NF + T C+ + GT WS P PRC A + IL
Sbjct: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
Query: 1149 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1193
Y N C++ ++ K I +A+ V + I
Sbjct: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Query: 1194 DGKDKTTHLLGAFTGASMR-----------GLTLSSTSNQLWL----------------- 1225
+G+ + H++ G S++ ++ TS +W
Sbjct: 418 NGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQ 477
Query: 1226 ------------EFNS--------------DTEGTDEGFQLVYTSFELSHCEDPGIPQFG 1259
+ NS + +GT F + E++ P I
Sbjct: 478 LLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGA 537
Query: 1260 YKISDQGHFA-GSTIIYGCNPG------YTLHGSSLLKCMTG--ERRAWDYPLPSC---- 1306
+ S F G+T+ Y CNPG ++L G S ++C + ER W P P C
Sbjct: 538 HTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSL 597
Query: 1307 IAECGGRFKGESSGRILSPGYPFPYDNNL--RCMWMIEVDPGNIVSLQFLAFDTEASHDI 1364
+A + +I P+ Y++ + +C + F + S I
Sbjct: 598 LAVQCSHVHIANGYKISGKEAPYFYNDTVTFKC---------------YSGFTLKGSSQI 642
Query: 1365 L----RVWDGPPENDMLLKE----ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1416
WD PE + KE + SL S + +V + + +G A Q
Sbjct: 643 RCKADNTWD--PEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQL--TGHAYQM 698
Query: 1417 SSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVFQCDPGYELQGEE 1460
C P V +NG G E G+ V ++CD G+ L GE+
Sbjct: 699 CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK 758
Query: 1461 RITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR---- 1508
++ C + W SPPV P N G+ L+ Y H+
Sbjct: 759 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH-SAYSHNDIVYV 814
Query: 1509 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQDSKLPERIESSS 1567
DC+ +N VI + D ++ P IG K P +
Sbjct: 815 DCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGG 865
Query: 1568 NTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RESCFDPGNIMNGTR 1608
N F S+ Y+ G+ L +A L +C P + M+G +
Sbjct: 866 NIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQ 922
Query: 1609 LGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1656
G++ Y+ G+ VT C+ GY+L+G C WN L C +
Sbjct: 923 KGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLAVCRS 970
Score = 52.4 bits (124), Expect = 8e-06
Identities = 123/519 (23%), Positives = 181/519 (34%), Gaps = 101/519 (19%)
Query: 177 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 235 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-TDFQME-EKY 292
C + P P Y + GD+++ T+F M K
Sbjct: 82 CEYFNKYSS--------CPEPIVPGGYKIRGSTPY----RHGDSVTFACKTNFSMNGNKS 129
Query: 293 DYLEIEGSEPPTIWLSGMNIPP------PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKK 346
+ + PT + +++ P P+I N + H + G S Y +
Sbjct: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGH----HTSENVGSIAPGLSVTYSCES 185
Query: 347 AIDFKSRGFKLFPGKD----NSNKFSILNEGGIKTASNLCPDPGEPENGK-RIGSDFSLG 401
G+ L K +S K+S + C G NGK + +G
Sbjct: 186 -------GYLLVGEKIINCLSSGKWSAVPP---TCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
T F CDE Y LQG S C IA AW+ PVC+ C S +G +
Sbjct: 236 VTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSL- 292
Query: 462 FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTLTIG-DGGEVGD-----PRTVL 514
+N ++T + + +NF + IG TL D + G PR L
Sbjct: 293 ----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
Query: 515 ----------QVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPG 564
Q+L G V S Q + D + + F K ++ C G
Sbjct: 345 STSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQG 397
Query: 565 T--PLYGIREGD----------GFSNRDVLRFE--------CQFGFELIGEKSIVCQENN 604
T P + E + +R ++RF+ C G+ L+GE+SI C
Sbjct: 398 TWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
Query: 605 QWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 638
W+ +P C + C + T P + PD G
Sbjct: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
Score = 48.1 bits (113), Expect = 2e-04
Identities = 137/667 (20%), Positives = 225/667 (33%), Gaps = 127/667 (19%)
Query: 729 ECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 785
ECP + N +N G S++ CE G++ G + I C L GK WS + P
Sbjct: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPP 208
Query: 786 KCG-APCGGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSI 829
C A C P+G + P G+ S C + +
Sbjct: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
Query: 830 KITFERFQTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLF 881
+ E F + H G +L + GS Y P+ NFI L
Sbjct: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRC 325
Query: 882 TTDNSRSN--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGY 936
T D+ ++ +G E ++ + C P I + GR ++ TV F+C G+
Sbjct: 326 TVDSQKTGTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGF 383
Query: 937 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGY 979
L + + C W P C+ C VR GT + +PGY
Sbjct: 384 TLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 980 PEFYPNSLNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT 1033
S+ CT WT V K + + H ++ N S + +L+
Sbjct: 444 VLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLS 502
Query: 1034 GSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF- 1092
GS +Y + + + + + E IT C P + G+ G
Sbjct: 503 GS---------VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSS 542
Query: 1093 --NFGIGDTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAEC 1137
+F G T+T++C+ G + L G S I C R WS P P C +C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 1138 GASATNNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDG 1195
N + P Y + +C ++ I A + V +
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCE---- 658
Query: 1196 KDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS----------- 1244
K+ H+ S++ L S + + T +Q+ +
Sbjct: 659 KETCQHV-----RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPL 713
Query: 1245 FELSHCEDPGIPQFGYK--ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGER--RAWD 1300
++ HC P + G + + G+ + Y C+ G+ L G L+C + + +W
Sbjct: 714 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773
Query: 1301 YPLPSCI 1307
P P C+
Sbjct: 774 GPSPQCL 780
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 375 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 431
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 844 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 899
Query: 432 WSDHRPVCKVKTCGS 446
WS P CK C S
Sbjct: 900 WSQPAPHCKEVNCSS 914
Score = 43.9 bits (102), Expect = 0.003
Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 34/252 (13%)
Query: 1602 NIMNGTRLG---MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC 1658
+I NG ++ Y TVT+ C +G+ L+G S + C + W+ +P C
Sbjct: 606 HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT----WDPEIPVCEKET 661
Query: 1659 GSR--------STGSEGTVLSPNYPKNYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLHD 1709
GS +++ + Y + GH Y + E ++ + + +H
Sbjct: 662 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHC 719
Query: 1710 ------VVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
V + G ++ L + + L ++ R S G + G
Sbjct: 720 HPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--P 777
Query: 1764 QAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSS---VLFDCNPGYILHGSIAIRCETVPNS 1820
Q + T+C + PE + G ++ + S V DCNPG+I++GS IRC T
Sbjct: 778 QCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT- 835
Query: 1821 LAQWNDSLPTCI 1832
W +PTCI
Sbjct: 836 ---WVPGVPTCI 844
Score = 42.4 bits (98), Expect = 0.008
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 382 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 438
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 439 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 497
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 779 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 826
Query: 498 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 545
+ G P + + G P I S M + D+
Sbjct: 827 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 886
Query: 546 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 591
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 887 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 946
Query: 592 LIGEKSIVCQENNQWSANIPIC 613
L G CQ ++QW+ + +C
Sbjct: 947 LEGSPQSQCQSDHQWNPPLAVC 968
Score = 38.9 bits (89), Expect = 0.091
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 1596 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1653
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1654 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1700
C P G + G S Y SV C + ++ V+ Q
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 1701 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1759
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
Query: 1760 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1810
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
Query: 1811 AIRCETVPNSLAQWNDSLPTC 1831
+ RC +A W +P C
Sbjct: 253 SSRCVIAGQGVA-WT-KMPVC 271
Score = 35.8 bits (81), Expect = 0.77
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 905 SCLDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPT 958
SC P ++GR Y ++G+ + +SC +RL E+ LLC + + W P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 959 CD 960
C+
Sbjct: 82 CE 83
Score = 35.8 bits (81), Expect = 0.77
Identities = 56/279 (20%), Positives = 105/279 (37%), Gaps = 63/279 (22%)
Query: 1070 FSEYNLEPCEDPGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS- 1127
F++Y+ C +P +P Y R + GD++TF+C + + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGP 140
Query: 1128 APLPRCVA----ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1183
LP CV+ EC P P+ + +H + G + S + +
Sbjct: 141 TRLPTCVSVFPLEC-------------PALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
Query: 1184 LAQGD--VLKIYDGK---------DKTTHLLGAFTGASMR-------GLTLSSTSNQLW- 1224
L G+ + + GK + LG F ++ G+T + ++ +
Sbjct: 188 LLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247
Query: 1225 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP---------QFGYKISDQGHFAGSTIIY 1275
L+ + G + +T + CE+ P G +++ + GS + Y
Sbjct: 248 LQGPPSSRCVIAGQGVAWTKMPV--CEEIFCPSPPPILNGRHIGNSLANVSY--GSIVTY 303
Query: 1276 GCNP------GYTLHGSSLLKCMTGERR--AWDYPLPSC 1306
C+P + L G S L+C ++ W P P C
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342
Score = 35.8 bits (81), Expect = 0.77
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 178 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 906
Query: 235 CR 236
C+
Sbjct: 907 CK 908
Score = 35.8 bits (81), Expect = 0.77
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 964
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 931 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 33.1 bits (74), Expect = 5.0
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 171 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 908 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 963
Query: 231 PVPICRA 237
P+ +CR+
Sbjct: 964 PLAVCRS 970
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 242 bits (617), Expect = 5e-63
Identities = 164/579 (28%), Positives = 241/579 (41%), Gaps = 59/579 (10%)
Query: 2697 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2756
+LP V ++C HP GN F+FN +F C GY + GP+K +C A+ W++ P
Sbjct: 204 ELPQHVLMNCSHP--------LGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKP 254
Query: 2757 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2816
P C C IP F + + + C G+ L G V+ C +G W
Sbjct: 255 PQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTA 314
Query: 2817 PLPECIMIDCGHPGVPPNAVLSG----EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 2872
P P C + C H P + + +GS+ + C + G C +GHW
Sbjct: 315 PAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHW 374
Query: 2873 SGSQPHCSGDATGTCGDPGTPGHGSRQESN----FRTKSTVRYACDTGYILHGSEERTCL 2928
S P C + C +P HGS S F+ + + C G++L G++ C
Sbjct: 375 SAPLPTCEAIS---CEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCD 431
Query: 2929 ANGSWTGRQPECKAVQCGNPGTTANGKV---FRIDGTTFSSSVIYSCMEGYILSGPSVRQ 2985
G WT P C+A+QC + +V + S ++C EG +L G SV Q
Sbjct: 432 NLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQ 491
Query: 2986 CTANGTWSGTLPNCTIISCGDPGIPANG----LRYGDDYVVGQNVSYMCQPGYTMELNGS 3041
C A G W+ P C I C P NG ++ ++C GY+ L+G
Sbjct: 492 CLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYS--LSGP 549
Query: 3042 RIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN----FDWGFSISYICSPGYELS 3097
CT +G W+ P C A+ CP G L+ ++ F+ G + + C G++L
Sbjct: 550 ERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLE 609
Query: 3098 FPAVLTCVGNGTWSGEVPQC-----LPKFCGDPGI-------PAQG----KREGKSFIYQ 3141
P + C +G WS P C LP PG+ P QG + +F +
Sbjct: 610 GPNNVECTTSGRWSATPPTCKGIASLPT----PGVQCPALTTPGQGTMYCRHHPGTFGFN 665
Query: 3142 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN--NTFG 3199
+ F CN F L+G ST C+ G W+ +P C C V + + N N +G
Sbjct: 666 TTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPAC---RAVKCSELHVNKPIAMNCSNLWG 722
Query: 3200 -FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3237
F GS+ FHC +G LL GS C + WS P C
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 226 bits (577), Expect = 2e-58
Identities = 172/644 (26%), Positives = 263/644 (40%), Gaps = 67/644 (10%)
Query: 2574 GTWSNHN----KTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSA-VR 2628
G W++ + K C SC ++ G + T +Y + C GF VR
Sbjct: 143 GKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCS----CYPGFYGPECEYVR 198
Query: 2629 ECLSSGLWSESETRCLAGHCGIPE-LIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2687
EC G +P+ +++N N+ + + C G+++ G S
Sbjct: 199 EC---------------GELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLE 243
Query: 2688 CQQDHNWSGQLPSCVPVSCGHPGSPIYGRT----SGNGFNFNDVVTFSCNIGYLMQGPTK 2743
C W+ + P C+ C P G S F +FSC G+ + GP
Sbjct: 244 CLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEV 303
Query: 2744 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2803
QC A+ W+ P P+CK V C P+ + F YG+ ++C PGY + G
Sbjct: 304 VQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGL 363
Query: 2804 SVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVL----SGEKYTFGSTVHYSCTGKRSLL 2859
+L C +G W PLP C I C P + + S + + + + C L
Sbjct: 364 DMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLR 423
Query: 2860 GQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG----SRQESNFRTKSTVRYACDT 2915
G C G W+ P C C D P S FR +S + C+
Sbjct: 424 GADIVRCDNLGQWTAPAPVCQ---ALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE 480
Query: 2916 GYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGK---VFRIDGTTFSSSVIYSC 2972
G +L G+ CLA G+W PEC+A+ C + NG V + +++ S+ + C
Sbjct: 481 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC 540
Query: 2973 MEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG-LRYGD---DYVVGQNVSY 3028
EGY LSGP CT +G W+ + P C I C + P G L D ++ VG +
Sbjct: 541 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF 600
Query: 3029 MCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV-TCPTP----PQISNGRLEGTNF--- 3080
C G+ +E G CT +G WS PTC+ + + PTP P ++ +GT +
Sbjct: 601 SCDNGFKLE--GPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPG-QGTMYCRH 657
Query: 3081 ---DWGFSIS--YICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD----PGIPAQG 3131
+GF+ + + C+ G+ L + L+C +G W+ P C C + I
Sbjct: 658 HPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNC 717
Query: 3132 KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3175
+F Y S SF C +L GS+ CQ +G WS + P C
Sbjct: 718 SNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 202 bits (515), Expect = 4e-51
Identities = 167/643 (25%), Positives = 257/643 (39%), Gaps = 82/643 (12%)
Query: 2700 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP-PM 2758
SC +SC G + T GN T SC G+ GP +C+ R+ P
Sbjct: 162 SCQDMSCSKQGECL--ETIGN-------YTCSCYPGFY--GP---ECEYVRECGELELPQ 207
Query: 2759 CKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPL 2818
++NCS P GNF++ + + C GY + G S L C +G W
Sbjct: 208 HVLMNCSHP-------------LGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKP 254
Query: 2819 PECIMIDCGHPGVPPNAVL----SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 2874
P+C+ C +P + S + + S+ +SC +L+G C +G W+
Sbjct: 255 PQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTA 314
Query: 2875 SQPHCSGDATGTCGDPGTPGHGSRQ----ESNFRTKSTVRYACDTGYILHGSEERTCLAN 2930
P C C P G+ + F S+ ++ C GY + G + C+ +
Sbjct: 315 PAPVCKAVQ---CQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDS 371
Query: 2931 GSWTGRQPECKAVQCGNPGTTANGKVF---RIDGTTFSSSVIYSCMEGYILSGPSVRQCT 2987
G W+ P C+A+ C + +G + + + ++ + C EG++L G + +C
Sbjct: 372 GHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCD 431
Query: 2988 ANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVG----QNV-SYMCQPGYTMELNGSR 3042
G W+ P C + C D +P N R + G Q+V S+ C G + L G+
Sbjct: 432 NLGQWTAPAPVCQALQCQDLPVP-NEARVNCSHPFGAFRYQSVCSFTCNEG--LLLVGAS 488
Query: 3043 IRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT----NFDWGFSISYICSPGYELSF 3098
+ C G W+ V P C+A+ C NG + + + + +IC GY LS
Sbjct: 489 VLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSG 548
Query: 3099 PAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS----FIYQSEVSFSCNFPFIL 3154
P L C +G W+ P C C + P QG + F S FSC+ F L
Sbjct: 549 PERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKL 608
Query: 3155 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV-------PRHGSQN-----NTFGFQV 3202
G + C G WS + P C S PGV P G+ TFGF
Sbjct: 609 EGPNNVECTTSGRWSATPPTC--KGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFN- 665
Query: 3203 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-----PETPAHANVVGMD 3257
+ F C G L G +T +C P W+ + P C C + P +N+ G
Sbjct: 666 -TTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNF 724
Query: 3258 LPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3300
S+G + C G L G+ C+ + W+ VP C+AG
Sbjct: 725 --SYGSICSFHCLEGQLL-NGSAQTACQENGHWSTTVPTCQAG 764
Score = 194 bits (494), Expect = 1e-48
Identities = 140/514 (27%), Positives = 216/514 (42%), Gaps = 40/514 (7%)
Query: 2461 IAFYCSTPESPPHGYII---SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2517
+A C + P G + S Q S ++C+ GF LVG C S W
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG----VWT 313
Query: 2518 APVPACQAISCGIPKAPTNGGI----LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSD 2573
AP P C+A+ C +AP+ G + T + G+ + C GYR+ ++ C
Sbjct: 314 APAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLR--CIDS 371
Query: 2574 GTWSNHNKTPRCVVISCGELPTPPNGNKIGTQT----SYGSTAIFTCDLGFMLVGSAVRE 2629
G WS P C ISC L +P +G+ + + Y + F C GFML G+ +
Sbjct: 372 GHWSA--PLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVR 429
Query: 2630 CLSSGLWSESETRCLAGHCG---IP-ELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSV 2685
C + G W+ C A C +P E VN + Y+ + CN G L+G+SV
Sbjct: 430 CDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASV 489
Query: 2686 RICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG----NGFNFNDVVTFSCNIGYLMQGP 2741
C NW+ P C + C SP G + ++ F C+ GY + GP
Sbjct: 490 LQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGP 549
Query: 2742 TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF 2801
+ C + +W+ PPMC+ + C + P + G F G+ + C+ G+ L
Sbjct: 550 ERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLE 609
Query: 2802 GSSVLICQPNGQWDKPLPECIMI-DCGHPGVPPNAVLS---GEKY------TFG--STVH 2849
G + + C +G+W P C I PGV A+ + G Y TFG +T +
Sbjct: 610 GPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCY 669
Query: 2850 YSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCG-DPGTPGHGSRQESNFRTKST 2908
+ C +L+G S+ +C+ +G W+ P C + + S NF S
Sbjct: 670 FGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSI 729
Query: 2909 VRYACDTGYILHGSEERTCLANGSWTGRQPECKA 2942
+ C G +L+GS + C NG W+ P C+A
Sbjct: 730 CSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQA 763
Score = 76.6 bits (187), Expect = 4e-13
Identities = 67/216 (31%), Positives = 89/216 (41%), Gaps = 35/216 (16%)
Query: 2462 AFYCSTPESPPHGYI-ISQTGGQLN--SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2518
A C +P G + S T G+ N S ++CD GF+L G ++ C S W A
Sbjct: 569 AIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSG----RWSA 624
Query: 2519 PVPACQAISCGIPKAPTNG-----------GILTTDYLVGT----RVTYF-CNDGYRLSS 2562
P C+ GI PT G G + + GT YF CN G+ L
Sbjct: 625 TPPTCK----GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIG 680
Query: 2563 KELTTAVCQSDGTWSNHNKTPRCVVISCGEL----PTPPNGNKIGTQTSYGSTAIFTCDL 2618
+T C+ G W+ TP C + C EL P N + + SYGS F C
Sbjct: 681 D--STLSCRPSGQWTA--VTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLE 736
Query: 2619 GFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELI 2654
G +L GSA C +G WS + C AG I E +
Sbjct: 737 GQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEAL 772
Score = 70.5 bits (171), Expect = 3e-11
Identities = 50/189 (26%), Positives = 77/189 (40%), Gaps = 10/189 (5%)
Query: 3137 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQ-- 3194
+F + S+ SF C + + G S C A G W+ P C+ C +P G+
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLA---AQCPPLKIPERGNMTC 275
Query: 3195 -NNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN- 3252
++ FQ S F C++G L G C W+ P C C+ E P+
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTM 335
Query: 3253 --VVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3310
V + ++G + + CQPG+ + G R C W+ +P CEA S ++ P
Sbjct: 336 DCVHPLTAFAYGSSCKFECQPGYRVRGLDMLR-CIDSGHWSAPLPTCEAISCEPLESPVH 394
Query: 3311 ALGTPSPKL 3319
SP L
Sbjct: 395 GSMDCSPSL 403
Score = 64.3 bits (155), Expect = 2e-09
Identities = 111/485 (22%), Positives = 171/485 (35%), Gaps = 123/485 (25%)
Query: 729 ECPDPGIP----INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 784
+CP IP + FQ SS S CEEGF G E + C +W+
Sbjct: 261 QCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALV-GPEVVQCTASG---VWTAPA 316
Query: 785 PKCGAPCGGHFSAPSGVILSPGWP-GYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYD 843
P C A H APS + P + +C++ E +PG+ ++ D
Sbjct: 317 PVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKF--ECQPGYRVR----------GLD 364
Query: 844 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 903
+L D + +PL T
Sbjct: 365 MLRCIDSGHWSAPL-----------------------------------------PTCEA 383
Query: 904 YSCLDPGIPVHGRRYGHD----FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
SC PVHG F + SF C G+ L + + C+ W+ P P C
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVC 443
Query: 960 DALCGGDVRGPSGTILSPGYP--EFYPNSLNCTWTVD---VTHGKGV-----QFNFHTFH 1009
AL D+ P+ ++ +P F S+ C++T + + G V N+++
Sbjct: 444 QALQCQDLPVPNEARVNCSHPFGAFRYQSV-CSFTCNEGLLLVGASVLQCLATGNWNSVP 502
Query: 1010 LEDHH---DYLLITENGSFT--QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1064
E LL +NG+ T QPL ++++ +FI D S
Sbjct: 503 PECQAIPCTPLLSPQNGTMTCVQPLGS---------------SSYKSTCQFICDEGYSLS 547
Query: 1065 G---FNITFS-EYNLEP-------CEDPGIPQYGSR----IGFNFGIGDTLTFSCSSGYR 1109
G + T S + P C + P+ GS F +G T FSC +G++
Sbjct: 548 GPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFK 607
Query: 1110 LEGTSEIICLGGGRRVWSAPLPRCV---------AECGASATNNEGILLSPNYPLNYENN 1160
LEG + + C GR WSA P C +C A T +G + ++P + N
Sbjct: 608 LEGPNNVECTTSGR--WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFN 665
Query: 1161 HECIY 1165
C +
Sbjct: 666 TTCYF 670
Score = 59.3 bits (142), Expect = 7e-08
Identities = 106/456 (23%), Positives = 169/456 (37%), Gaps = 87/456 (19%)
Query: 1053 LRFISDFSIS-YEGFNITFSEYNLEPCEDPGIPQY-----GSRIGFNFGIGDTLTFSCSS 1106
L I +++ S Y GF EY E C + +PQ+ +G NF +F C+
Sbjct: 175 LETIGNYTCSCYPGFYGPECEYVRE-CGELELPQHVLMNCSHPLG-NFSFNSQCSFHCTD 232
Query: 1107 GYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHECIY 1165
GY++ G S++ CL G +W+ P+C+A +C P + N C++
Sbjct: 233 GYQVNGPSKLECLASG--IWTNKPPQCLAAQC-------------PPLKIPERGNMTCLH 277
Query: 1166 SIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWL 1225
S + + S+ +F +G L + T G +T + +
Sbjct: 278 SAKAFQHQ----SSCSFSCEEGFALVGPEVVQCTAS--GVWTAPAPVCKAVQCQ------ 325
Query: 1226 EFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1285
+ +EGT + C P + F Y GS+ + C PGY + G
Sbjct: 326 HLEAPSEGTMD-------------CVHP-LTAFAY---------GSSCKFECQPGYRVRG 362
Query: 1286 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRI-LSPGY-PFPYDNN--LRCMWMI 1341
+L+C+ + W PLP+C A + G + SP F YD N RC
Sbjct: 363 LDMLRCI--DSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF 420
Query: 1342 EVDPGNIVSLQFLAFDTEASH--DILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTI 1399
+ +IV L T + L+ D P N+ + P G ++ +
Sbjct: 421 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARV----NCSHPFGAFRYQSVCSF 476
Query: 1400 QFDTDFYISKSG----FAIQFSSSVATACRD-PGVPMNGTRNG--------DGREPGDTV 1446
+ + + A +SV C+ P P+ +NG T
Sbjct: 477 TCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTC 536
Query: 1447 VFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1482
F CD GY L G ER+ C + W SPP+C A
Sbjct: 537 QFICDEGYSLSGPERLDCTRSGR---WTDSPPMCEA 569
Score = 56.6 bits (135), Expect = 4e-07
Identities = 109/514 (21%), Positives = 172/514 (33%), Gaps = 83/514 (16%)
Query: 1582 YTGFH---LEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCI 1638
Y GF+ EY + E +MN + ++ S +++C GY + G S L C+
Sbjct: 186 YPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECL 245
Query: 1639 MGDDGRPGWNRALPSC-HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVF 1697
W P C A C G + + K + +C +S + F +
Sbjct: 246 ASGI----WTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCE--EGFALV 299
Query: 1698 GQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGES---LPLSS-GNQITIRFTSVGP 1753
G V T+ V P ++ L G PL++ + +F
Sbjct: 300 GPEVVQCTA--SGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPG 357
Query: 1754 ITAKGFHFVY--------QAVPRTSSTQCSSVPEPRFGRRIGNE----FAVGSSVLFDCN 1801
+G + +P + C + P G + F ++ F C
Sbjct: 358 YRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCA 417
Query: 1802 PGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNC 1861
G++L G+ +RC+ +L QW P C + P P + +NC
Sbjct: 418 EGFMLRGADIVRCD----NLGQWTAPAPVC------------QALQCQDLPVPNEARVNC 461
Query: 1862 -----------VWKITVPEGAG-IQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGT- 1908
V T EG + V+ NW+S+ P L +GT
Sbjct: 462 SHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTM 521
Query: 1909 TIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIG--LDS--------CPEPQTPSSG 1957
T L S+S F D S +G L+ T G DS CPE P G
Sbjct: 522 TCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQG 581
Query: 1958 -IKIGD---RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICL--------- 2004
+ D + VG F CD G+ L+G +++ C RW+ P C
Sbjct: 582 SLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTS--GRWSATPPTCKGIASLPTPG 639
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIN 2038
QC + G + PG + + C + N
Sbjct: 640 VQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCN 673
Score = 53.5 bits (127), Expect = 4e-06
Identities = 121/600 (20%), Positives = 189/600 (31%), Gaps = 168/600 (28%)
Query: 1448 FQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAP-CGGNLTGSSGFILSPNFPHPYPH 1506
F C GY++ G ++ C+ W PP C+A C G + + + H
Sbjct: 228 FHCTDGYQVNGPSKLECLASG---IWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQH 284
Query: 1507 SRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESS 1566
C SFS E + + GP+ + P + +
Sbjct: 285 QSSC-----------------SFSCEEGFALV----GPEVVQCTASGVWTAPAP--VCKA 321
Query: 1567 SNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAG 1626
HL S+G++ C P + GS+ + C G
Sbjct: 322 VQCQHLEAPSEGTMD---------------CVHPLTA---------FAYGSSCKFECQPG 357
Query: 1627 YVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1685
Y ++G L CI D G W+ LP+C A C + G++ + + NC
Sbjct: 358 YRVRGLDMLRCI--DSGH--WSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCS 413
Query: 1686 YSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQIT 1745
+ A + F++ G +
Sbjct: 414 FRCA--EGFMLRGADI-------------------------------------------- 427
Query: 1746 IRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGR----RIGNEFAVGSSVLFDCN 1801
+R ++G TA P + QC +P P R F S F CN
Sbjct: 428 VRCDNLGQWTAPA--------PVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCN 479
Query: 1802 PGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGT--------------- 1845
G +L G+ ++C N WN P C +PC +L+ + GT
Sbjct: 480 EGLLLVGASVLQCLATGN----WNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKST 535
Query: 1846 ---ILSPGYPEPYDNNLNCV----WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNN 1898
I GY L+C W + P I+ + FA E SLD D
Sbjct: 536 CQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPEL-FAPEQG--SLDCSD----- 587
Query: 1899 APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG--FHLEYTAIGLDSCPEP----- 1951
G ++ + H S N L +++ + +G T G+ S P P
Sbjct: 588 --TRGEFNVGSTCHF--SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCP 643
Query: 1952 --QTPSSGIKI----GDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
TP G + F C+ G++L G S ++C P +W P C A
Sbjct: 644 ALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPS--GQWTAVTPACRA 701
Score = 52.8 bits (125), Expect = 6e-06
Identities = 91/450 (20%), Positives = 161/450 (35%), Gaps = 80/450 (17%)
Query: 570 IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVL 629
+ F ++ F C+ GF L+G + + C + W+A P+C + AP +
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTM 335
Query: 630 SPDYP-EGYGNNLNCIWTIISDPGSRIH-----LSFNDFDLESQFDFLAVKDGDSPESPI 683
+P + +C + PG R+ + + + ESP+
Sbjct: 336 DCVHPLTAFAYGSSCKFEC--QPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV 393
Query: 684 LGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY-NTFGH----------NECPD 732
G+ + L + + F+ RG +I + G +C D
Sbjct: 394 HGSM---DCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQD 450
Query: 733 PGIPINAR-----RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
+P AR FG F+ S S C EG + G + C+ W+ + P+C
Sbjct: 451 LPVPNEARVNCSHPFGA-FRYQSVCSFTCNEGLLLV-GASVLQCLATGN---WNSVPPEC 505
Query: 788 GA-PCGGHFSAPSGVI--LSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNY-- 842
A PC S +G + + P YK + C+++ + G+S+ ER +
Sbjct: 506 QAIPCTPLLSPQNGTMTCVQPLGSSSYKST--CQFI--CDEGYSLSGP-ERLDCTRSGRW 560
Query: 843 ----DVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKI---- 894
+ E P L +P GS + S + + + +T + +NGFK+
Sbjct: 561 TDSPPMCEAIKCPELFAPEQGSLD--------CSDTRGEFNVGSTCHFSCDNGFKLEGPN 612
Query: 895 HYESVTVNTYSCLDP------GIPVHG----------------RRYGHDFSIGSTVSFSC 932
+ E T +S P +P G R + F +T F C
Sbjct: 613 NVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGC 672
Query: 933 DSGYRLSHEEPLLCEKNHWWSHPLPTCDAL 962
++G+ L + L C + W+ P C A+
Sbjct: 673 NAGFTLIGDSTLSCRPSGQWTAVTPACRAV 702
Score = 48.5 bits (114), Expect = 1e-04
Identities = 60/287 (20%), Positives = 96/287 (33%), Gaps = 38/287 (13%)
Query: 192 TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGI 251
T F G ++ C GY + G L CI ++ W P+P C A
Sbjct: 342 TAFAYGSSCKFECQPGYRVRGLDMLRCI----DSGHWSAPLPTCEA-------------- 383
Query: 252 ISSPSFPNEYHNNADCTWTIVAEPGDT-ISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 310
IS + H + DC+ ++ A DT S + M D + + L
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDN-------LGQW 436
Query: 311 NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSIL 370
P P+ L ++ ++ + F L G +
Sbjct: 437 TAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATG 496
Query: 371 NEGGIKTASNLCPDPG--EPENG-----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQ 423
N + P P+NG + +GS S ST QF CDE Y L G + + C
Sbjct: 497 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCT 555
Query: 424 RIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQC 470
R W+D P+C+ C G+ + +++ + C
Sbjct: 556 RSGR----WTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Score = 46.6 bits (109), Expect = 4e-04
Identities = 51/217 (23%), Positives = 80/217 (36%), Gaps = 46/217 (21%)
Query: 921 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILS-PGY 979
+F++GST FSCD+G++L + C + WS PTC + G L+ PG
Sbjct: 591 EFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQ 650
Query: 980 PEFYPNSLNCTWTVDVTHGKGVQFNFHTF-HLEDHHDYLLITENGSFTQPLARLTGSDLP 1038
Y H G F F+T + + + LI ++ +P + T +
Sbjct: 651 GTMY-----------CRHHPGT-FGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTA--VT 696
Query: 1039 PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGD 1098
P A + SE ++ + I S + NF G
Sbjct: 697 PACRA------------------------VKCSELHV----NKPIAMNCSNLWGNFSYGS 728
Query: 1099 TLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1135
+F C G L G+++ C G WS +P C A
Sbjct: 729 ICSFHCLEGQLLNGSAQTACQENGH--WSTTVPTCQA 763
Score = 45.8 bits (107), Expect = 7e-04
Identities = 64/261 (24%), Positives = 98/261 (37%), Gaps = 47/261 (18%)
Query: 923 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEF 982
S ST F CD GY LS E L C ++ W+ P C+A+ ++ P
Sbjct: 531 SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE----------- 579
Query: 983 YPNSLNCTWTVDVTHGKGVQFNF-HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTI 1041
SL+C+ T +G +FN T H + + L N R + + PPT
Sbjct: 580 -QGSLDCSDT------RG-EFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSAT--PPTC 629
Query: 1042 NAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLT 1101
G + +++ G + ++ PG FG T
Sbjct: 630 K----GIASLPTPGVQCPALTTPGQGTMYCRHH------PG----------TFGFNTTCY 669
Query: 1102 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENN 1160
F C++G+ L G S + C G+ W+A P C A +C N + N N+
Sbjct: 670 FGCNAGFTLIGDSTLSCRPSGQ--WTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYG 727
Query: 1161 HECIYSIQVQAGKGINISART 1181
C S G+ +N SA+T
Sbjct: 728 SIC--SFHCLEGQLLNGSAQT 746
Score = 42.7 bits (99), Expect = 0.006
Identities = 61/262 (23%), Positives = 96/262 (36%), Gaps = 53/262 (20%)
Query: 398 FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGP--SGTF 455
F+ GS+ +F C Y ++G + C WS P C+ +C L+ P
Sbjct: 344 FAYGSSCKFECQPGYRVRGLDMLRCIDSGH----WSAPLPTCEAISC-EPLESPVHGSMD 398
Query: 456 TSPNF-PFQYDSNA--QCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRT 512
SP+ FQYD+N +C E F L G D + + G+ P
Sbjct: 399 CSPSLRAFQYDTNCSFRCA----------------EGFMLR-GADIVRCDNLGQWTAPAP 441
Query: 513 VLQVLTGSFVP---DLIVSMSS-------QMWLHLQTDESVGSVGFKV-------NYKEI 555
V Q L +P + V+ S Q +E + VG V N+ +
Sbjct: 442 VCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSV 501
Query: 556 EKESCGDPGTPLYGIREGD--------GFSNRDVLRFECQFGFELIGEKSIVCQENNQWS 607
E P TPL + G S + +F C G+ L G + + C + +W+
Sbjct: 502 PPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWT 561
Query: 608 ANIPIC-IFPCLSNFTAPMGTV 628
+ P+C C F G++
Sbjct: 562 DSPPMCEAIKCPELFAPEQGSL 583
Score = 42.4 bits (98), Expect = 0.008
Identities = 53/240 (22%), Positives = 74/240 (30%), Gaps = 66/240 (27%)
Query: 382 CPDPGEPENGKRI----GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 437
CP PE G F S+ FSC+E + L G + + C W+ P
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQC----TASGVWTAPAP 317
Query: 438 VCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 497
VCK C +L+ PS + CV +TA + + G D
Sbjct: 318 VCKAVQC-QHLEAPS------------EGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLD 364
Query: 498 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEK 557
L D G P L T E++
Sbjct: 365 MLRCIDSGHWSAP--------------------------LPTCEAI-------------- 384
Query: 558 ESCGDPGTPLYGIREGD----GFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
SC +P++G + F F C GF L G + C QW+A P+C
Sbjct: 385 -SCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVC 443
Score = 42.0 bits (97), Expect = 0.011
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 2136 FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2178
F G + FEC PGY + G L C+ S +W+ PLP CEA+
Sbjct: 344 FAYGSSCKFECQPGYRVRGLDMLRCID--SGHWSAPLPTCEAI 384
Score = 42.0 bits (97), Expect = 0.011
Identities = 64/265 (24%), Positives = 95/265 (35%), Gaps = 28/265 (10%)
Query: 2111 VYQAYQLQSCPDPRPFR-NGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWN 2169
V QA Q Q P P R N F SF C G L+G S L CL + NWN
Sbjct: 442 VCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCL--ATGNWN 499
Query: 2170 HPLPRCEAL-CGGNITAMNGT------IYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT 2222
P C+A+ C ++ NGT + S Y D + + P +
Sbjct: 500 SVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR 559
Query: 2223 VLQTEPIYDFITVWD--GPDQNSPQIGQFSG--NTALESVYSTSNQILIK--FHSDFTTS 2276
+ P+ + I + P+Q S G N +S N ++ + + TTS
Sbjct: 560 WTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTS 619
Query: 2277 GFFVLSYHAYQLRVCQPPPPVPNAEILT----------EDDEFEIGDIIRYQCLPGFTLV 2326
G + + + P P V + T F + C GFTL+
Sbjct: 620 GRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLI 679
Query: 2327 GNAILTCRLGERLQMDGAPPVCQVL 2351
G++ L+CR Q P C+ +
Sbjct: 680 GDSTLSCRPSG--QWTAVTPACRAV 702
Score = 42.0 bits (97), Expect = 0.011
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 8/63 (12%)
Query: 382 CPDPGEPENGKRIGSD----FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 437
CP+ PE G SD F++GST FSCD + L+G ++ C WS P
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVEC----TTSGRWSATPP 627
Query: 438 VCK 440
CK
Sbjct: 628 TCK 630
Score = 35.4 bits (80), Expect = 1.0
Identities = 15/38 (39%), Positives = 17/38 (44%)
Query: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
FS + F C G L G CQEN WS +P C
Sbjct: 724 FSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 35.0 bits (79), Expect = 1.3
Identities = 46/223 (20%), Positives = 73/223 (32%), Gaps = 63/223 (28%)
Query: 1443 GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI---------APCGGNLTGSSG 1493
G T F CD G++L+G + C W +PP C C T G
Sbjct: 595 GSTCHFSCDNGFKLEGPNNVECTTSGR---WSATPPTCKGIASLPTPGVQCPALTTPGQG 651
Query: 1494 FILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGS 1553
+ + P + + C Y G ++ LIG
Sbjct: 652 TMYCRHHPGTFGFNTTC------------------------------YFGCNAGFTLIG- 680
Query: 1554 FQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDY 1613
DS L R + A R+ K E + MN + L ++
Sbjct: 681 --DSTLSCRPSGQWTAVTPACRA--------------VKCSELHVNKPIAMNCSNLWGNF 724
Query: 1614 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1656
GS +++C G +L G + C ++G W+ +P+C A
Sbjct: 725 SYGSICSFHCLEGQLLNGSAQTAC--QENGH--WSTTVPTCQA 763
Score = 32.7 bits (73), Expect = 6.5
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 1613 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPG--WNRALPSCHA-PCGSRSTGSEGTV 1669
+ +T + C+AG+ L G STL+C RP W P+C A C +
Sbjct: 662 FGFNTTCYFGCNAGFTLIGDSTLSC------RPSGQWTAVTPACRAVKCSELHVNKPIAM 715
Query: 1670 LSPNYPKNYSVGHNCVY 1686
N N+S G C +
Sbjct: 716 NCSNLWGNFSYGSICSF 732
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 233 bits (595), Expect = 2e-60
Identities = 167/515 (32%), Positives = 247/515 (47%), Gaps = 18/515 (3%)
Query: 1135 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1193
A C S +N EG + S +YPL NN EC Y++ V G G+ + ++ +L+ G++L I
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
Query: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1253
G D T + A + G + S +N + + F + + FQL Y +F LS C P
Sbjct: 339 -GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFP 396
Query: 1254 GIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1313
P G ++ +G + C+ GY L G+ +L C+ + W P C A CGG
Sbjct: 397 RRPDSG-DVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGA 455
Query: 1314 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1373
+ GR+LSP YP + + C+W IE G + L F D + V G
Sbjct: 456 VHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTN 514
Query: 1374 NDMLLKE-ISGSLIP-EGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
LL + + +P EG+ S N + I+F +D + S F I+F + C +P +
Sbjct: 515 KSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQN 574
Query: 1432 -NGTRNGDGREPGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1489
N T + G V F CDPG+ L QG I CI V + Y W + P+C A CGG L+
Sbjct: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLCRAMCGGELS 633
Query: 1490 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1549
+G +LSPN+P PY DC W I V + I L I F N D L IYDG +
Sbjct: 634 AVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNSDILTIYDGDEVMPH 692
Query: 1550 LIGSFQDSKLPERIESSSNTMHLAFRSDGS----VSYTGFHLEY-KAKLRESCFDPGNIM 1604
++G + + P+++ SS+ + + F SD + GF + Y + +SC D I
Sbjct: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQ 752
Query: 1605 NGTRLGMDYKL--GSTVTYYCDAGYVLQGYSTLTC 1637
NG + +L G+ +TY CD GY + G TLTC
Sbjct: 753 NGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC 787
Score = 228 bits (580), Expect = 1e-58
Identities = 191/714 (26%), Positives = 306/714 (42%), Gaps = 87/714 (12%)
Query: 1835 CGGILTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAGIQVQVVSF-ATEHNWDSLDFY 1892
C + +G I S YP P +N L C + +TV G G+++QV S ++ S+
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGV 340
Query: 1893 DGGDNNAPRLGSYSGTTI---PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 1949
DG P L + T+ ++ S +N + + F++ F L Y A L SC
Sbjct: 341 DG-----PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCN 394
Query: 1950 EPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
P+ P SG + + D + G V F C GY LQG +TC+ W+ PIC A CG
Sbjct: 395 FPRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
Query: 2009 GAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2067
GA+ + + G +LSP +P N S C WTI P G +HL F D + V SG
Sbjct: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQ 512
Query: 2068 SETSTVI-GRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2125
+ S ++ L +P L S + + F SD ++ F+I ++A++ C +P
Sbjct: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
Query: 2126 FRNGFVIGND--FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGN 2182
+NG +D + +G + F C PG++L G + + C++ WN P C A+CGG
Sbjct: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
Query: 2183 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2242
++A+ G + SP +P+ Y +DC W + V I+++ L D +T++DG +
Sbjct: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN-SDILTIYDGDEVM 690
Query: 2243 SPQIGQFSGNTALESVYSTSNQILIKFHSD-----FTTSGFFVLSY-HAYQLRVCQPPPP 2296
+GQ+ GN+ + +YS++ + I+FHSD F F+++Y + C P
Sbjct: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
Query: 2297 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2356
+ N T E G I YQC PG+ +VG+ LTC+ L PP C+ + +
Sbjct: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEKIMYCTD 808
Query: 2357 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI 2416
PG D L I
Sbjct: 809 -----------PGEVDHSTRL--------------------------------------I 819
Query: 2417 QSPV-LISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESP 2471
PV L+ + Y+ G + +S + G R+ + + C P P
Sbjct: 820 SDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP 879
Query: 2472 PHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
+GY I L + + C GF L+G+ + C + W+ P+P C+
Sbjct: 880 ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH--WNGPLPVCK 931
Score = 215 bits (547), Expect = 7e-55
Identities = 184/655 (28%), Positives = 286/655 (43%), Gaps = 45/655 (6%)
Query: 2005 AQCGGAMSDFSGVILSPGFP----GNYPSSLDCTWTINLPIGFGVHLQF--VNFSTETIH 2058
A C + S+ G I S +P N+ L+CT+ + + G+GV LQ VN S +
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNF---LECTYNVTVYTGYGVELQVKSVNLSDGEL- 334
Query: 2059 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
L +R T TV+ + + S T+ S+YF + F + YQA+ L
Sbjct: 335 --LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML- 391
Query: 2119 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2178
SC PR +G V D G F C GY L G LTC++ +W+ P C A
Sbjct: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
Query: 2179 CGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWD 2237
CGG + A G + SP YP+ Q C W + P G ++++F L D +TV
Sbjct: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHS 510
Query: 2238 GPDQNSPQIGQF--SGNTALESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPP 2294
G S + + + E + S N I I+F SD + F + + A++ C P
Sbjct: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
Query: 2295 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCP 2353
+ N T D + IG I+ + C PG +L G AI+ C + P+C+ +C
Sbjct: 571 Y-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC- 628
Query: 2354 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2413
EL + GV+LSP +P+ Y + C W I V + I + ++F D+L +YDG
Sbjct: 629 GGELSAVA-GVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 2414 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN----NKKGFRIRYIAFY----C 2465
+ +L G+ S + S+ ++ +Q+ +D +GF + YI C
Sbjct: 687 DEVMPHILGQYLGN-SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
Query: 2466 STPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
S +G+ S T + + + CD G+ +VG + C+ +W + P C+
Sbjct: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL----SWSSDPPFCE 801
Query: 2525 AIS-CGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
I C P + L +D LVGT + Y CN G+ L L T + GT ++
Sbjct: 802 KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR 861
Query: 2582 TPRCV---VISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECL 2631
P CV ++C P NG +I + Y G + F C GF L+G C+
Sbjct: 862 LPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
Score = 210 bits (535), Expect = 2e-53
Identities = 204/718 (28%), Positives = 307/718 (42%), Gaps = 88/718 (12%)
Query: 1482 APCGGNLTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1540
A C + + G+I S ++P P + +C + +TV Y + L S ++ + L I
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
Query: 1541 --YDGPD----SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1594
DGP +N L+ Q I S +NT+ + FR+ F L Y+A +
Sbjct: 338 RGVDGPTLTVLANQTLLVEGQV------IRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
Query: 1595 ESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
SC P +G MD G ++C GY LQG LTCI + +P W+ P C
Sbjct: 392 -SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASKPHWSSQEPIC 448
Query: 1655 HAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEV 1713
APCG + G VLSP+YP+N + C+++I P+ + F D + V
Sbjct: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
Query: 1714 YDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPRT 1769
+ G T +S+LL S ES+P LS GN I I FTS A F+ ++A +
Sbjct: 509 HSGQTNKSALLYD---SLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
Query: 1770 SSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWND 1826
+ P + G ++ + +G+ V F C+PG+ L G I C V + WND
Sbjct: 566 HCYE----PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WND 619
Query: 1827 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1886
+ P C CGG L+ G +LSP +PEPY +C+WKI V E I + + F N
Sbjct: 620 TEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNS 678
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSD----ISVSAAGFHLEYTA 1942
D L YDG + LG Y G + P L S++ +L + F SD I GF + Y
Sbjct: 679 DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
Query: 1943 IGL-DSCPEPQTPSSGIKIGD--RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 1999
+ DSC + +G K + G +++QCD GY + G +TC W+
Sbjct: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
Query: 2000 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF-GVHLQFVNFSTETIH 2058
P C I+ PG S T I+ P+ G +Q+ +
Sbjct: 797 PPFC------------EKIMYCTDPGEVDHS---TRLISDPVLLVGTTIQYTCNPGFVLE 841
Query: 2059 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
+ S ET T P S L E SL + + G+ I+Y+ L
Sbjct: 842 GSSLLTCYSRETGT-------PIWTSRLPHCVSEESLACDNP-GLPENGYQILYKRLYLP 893
Query: 2119 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
G++++F C+ G+ L+G + C+ G +WN PLP C+
Sbjct: 894 --------------------GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 203 bits (517), Expect = 2e-51
Identities = 158/526 (30%), Positives = 246/526 (46%), Gaps = 29/526 (5%)
Query: 1320 GRILSPGYPF-PYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDI-LRVWDGPPENDML 1377
G I S YP P +N L C + + V G V LQ + + + +R DGP L
Sbjct: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPT----L 345
Query: 1378 LKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTR 1435
+ +L+ EG I S N +++ F T F + + + + + C P P +G
Sbjct: 346 TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFPRRPDSGDV 404
Query: 1436 NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSS-GF 1494
G F C GYELQG + +TCI + W P+C APCGG + ++ G
Sbjct: 405 TVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGR 463
Query: 1495 ILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLI-GS 1553
+LSP++P S+ C WTI + L F + D + ++ G + S L+ S
Sbjct: 464 VLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDS 522
Query: 1554 FQDSKLP-ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD 1612
Q +P E + S NT+ + F SD + + + F++ ++A + C++P I NG D
Sbjct: 523 LQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSD 581
Query: 1613 --YKLGSTVTYYCDAGYVL-QGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1669
Y +G+ V + CD G+ L QG + + CI D P WN P C A CG + G V
Sbjct: 582 PTYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVV 639
Query: 1670 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1729
LSPN+P+ Y G +C++ I V +E +F F S D++ +YDG +L G
Sbjct: 640 LSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG 699
Query: 1730 SHSGESLPLSSGNQITIRFTS--VGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG 1787
+SG SS +TI+F S G I KG F+ + + + CS +PE + G +
Sbjct: 700 -NSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTT 758
Query: 1788 N--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
+ E G+ + + C+PGY + GS + C+ W+ P C
Sbjct: 759 SHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFC 800
Score = 201 bits (511), Expect = 1e-50
Identities = 203/744 (27%), Positives = 310/744 (41%), Gaps = 87/744 (11%)
Query: 759 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGY-YKDSLNC 817
G + ET T ++ V+ + P A C FS P G I S +P + L C
Sbjct: 252 GSASEESQETTTSTIITTTVITTEQAP---ALCSVSFSNPEGYIDSSDYPLLPLNNFLEC 308
Query: 818 EWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLLGSYNGTQVPQFLFSSSN 875
+ + G+ +++ + + ++L + DGP L +L + Q + S +N
Sbjct: 309 TYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTN 365
Query: 876 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 935
I + F T F++HY++ + SC P P G D G F C G
Sbjct: 366 TISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLG 422
Query: 936 YRLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPS-GTILSPGYPEFYPNSLNCTW 991
Y L + L C K HW S P C A CGG V + G +LSP YPE S C W
Sbjct: 423 YELQGAKMLTCINASKPHWSSQE-PICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIW 481
Query: 992 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTIN-AGLYGNFR 1050
T++ G+ + +F L HD +T + T A L S ++ GL
Sbjct: 482 TIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
Query: 1051 A-QLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFN--FGIGDTLTFSCSSG 1107
++ F SD + + FNI F + C +P I Q G+ + + IG + F+C G
Sbjct: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
Query: 1108 YRLE-GTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYS 1166
+ LE G + I C+ W+ P C A CG + G++LSPN+P Y +CI+
Sbjct: 598 HSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWK 657
Query: 1167 IQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLE 1226
I V K I + + +L+ D+L IYDG + H+LG + G S SST + L ++
Sbjct: 658 IHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPD-LTIQ 716
Query: 1227 FNSDTE----GTDEGFQLVYTSFELS-HCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPG 1280
F+SD G +GF + Y + C D Q G+K + G+ I Y C+PG
Sbjct: 717 FHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
Query: 1281 YTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWM 1340
Y + GS L C + D P I C + + S R++S
Sbjct: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS---------------- 820
Query: 1341 IEVDPGNIV--SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVT 1398
DP +V ++Q+ + + EG S L +
Sbjct: 821 ---DPVLLVGTTIQYTC--------------------------NPGFVLEG-SSLLTCYS 850
Query: 1399 IQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYEL 1456
+ T + S+ + S + AC +PG+P NG + R PG+++ F C G+EL
Sbjct: 851 RETGTPIWTSRLPHCV---SEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFEL 907
Query: 1457 QGEERITCIQVENRYFWQPSPPVC 1480
GE I CI + + W PVC
Sbjct: 908 MGEVTIRCILGQPSH-WNGPLPVC 930
Score = 170 bits (431), Expect = 2e-41
Identities = 183/719 (25%), Positives = 297/719 (41%), Gaps = 98/719 (13%)
Query: 617 CLSNFTAPMGTVLSPDYPEGYGNN-LNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 675
C +F+ P G + S DYP NN L C + + G + L +L S + L+++
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSIRG 339
Query: 676 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 735
D P +L T + S ++ + + F+ F + Y F C P
Sbjct: 340 VDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCNFPRR 398
Query: 736 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH- 794
P + + G C G+ + QG + +TCI K WS P C APCGG
Sbjct: 399 PDSGDVTVMDLHSGGVAHFHCHLGY-ELQGAKMLTCI-NASKPHWSSQEPICSAPCGGAV 456
Query: 795 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 854
+A G +LSP +P S C W IEA G + + FER + D + VH G
Sbjct: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNK 515
Query: 855 SPLL-GSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 912
S LL S VP + L S N I + FT+D +R+ + F I +E+ C +P I
Sbjct: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG--HCYEPYIQ 573
Query: 913 VHGRRYGHD--FSIGSTVSFSCDSGYRLSHEEPLLCE----KNHWWSHPLPTCDALCGGD 966
+G D ++IG+ V F+CD G+ L + P + E ++ +W+ P C A+CGG+
Sbjct: 574 -NGNFTTSDPTYNIGTIVEFTCDPGHSL-EQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
Query: 967 VRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT 1026
+ +G +LSP +PE Y +C W + V K + + +L + D L I +
Sbjct: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYD----- 685
Query: 1027 QPLARLTGSDLPPTINAGLYGNFRAQLRFIS--DFSISY------------EGFNITFSE 1072
G ++ P I GN Q + S D +I + +GF + + E
Sbjct: 686 -------GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
Query: 1073 YNL-EPCEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAP 1129
+ + C D Q G + + + G +T+ C GY + G+ + C WS+
Sbjct: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
Query: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV 1189
P C E I+ + P +++ I + G I + G V
Sbjct: 797 PPFC-----------EKIMYCTD-PGEVDHSTRLISDPVLLVGTTIQYTCN-----PGFV 839
Query: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY-TSFELS 1248
L+ G+S+ T +W +L + S E
Sbjct: 840 LE----------------GSSLLTCYSRETGTPIWTS------------RLPHCVSEESL 871
Query: 1249 HCEDPGIPQFGYKI-SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1306
C++PG+P+ GY+I + + G ++ + C G+ L G ++C+ G+ W+ PLP C
Sbjct: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 134 bits (338), Expect = 1e-30
Identities = 140/569 (24%), Positives = 225/569 (39%), Gaps = 61/569 (10%)
Query: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNN-ADCTWTIVAEPGDTISLIFTDFQMEEKYDY 294
+A C + G I S +P NN +CT+ + G + L + + +
Sbjct: 276 QAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-EL 334
Query: 295 LEIEGSEPPTIWLSG---MNIPPPII-SNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
L I G + PT+ + + + +I S N + ++F T + F YQ
Sbjct: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA------ 388
Query: 351 KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDE 410
F L C P P++G D G F C
Sbjct: 389 ----FMLS-----------------------CNFPRRPDSGDVTVMDLHSGGVAHFHCHL 421
Query: 411 DYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQC 470
Y LQGAK +TC ++ WS P+C G+ G SP++P + + C
Sbjct: 422 GYELQGAKMLTCINASKPH--WSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
Query: 471 VWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-DLIVSM 529
+W I A K + ++FE L D +T+ G+ + L VP + ++S
Sbjct: 480 IWTIEAPEGQK-LHLHFERLLLH-DKDRMTV-HSGQTNKSALLYDSLQTESVPFEGLLSE 536
Query: 530 SSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSN-RDVLRFECQF 588
+ + + +D++ + F + ++ EK C +P D N ++ F C
Sbjct: 537 GNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDP 596
Query: 589 GFELI-GEKSIVC--QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIW 645
G L G I C + W+ P+C C +A G VLSP++PE Y +CIW
Sbjct: 597 GHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIW 656
Query: 646 TIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRL 705
I RI L +L S D L + DGD ILG + G P L S++ L +
Sbjct: 657 KIHVGEEKRIFLDIQFLNL-SNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTI 715
Query: 706 EFQADHS----MSGRGFNITYNTFGHNE-CPDPGIPINARRFGDNFQL--GSSISVICEE 758
+F +D + G+GF + Y N+ C D N + + +L G+ I+ C+
Sbjct: 716 QFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDP 775
Query: 759 GFIKTQGTETITCILMDGKVMWSGLIPKC 787
G+ G++T+TC + WS P C
Sbjct: 776 GY-DIVGSDTLTC---QWDLSWSSDPPFC 800
Score = 132 bits (332), Expect = 6e-30
Identities = 127/470 (27%), Positives = 208/470 (44%), Gaps = 73/470 (15%)
Query: 166 FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNT 225
F+++Y+ S C P P G + G + C GY L G LTCI + +
Sbjct: 382 FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASK 438
Query: 226 ASWDFPVPICRAEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFT 284
W PIC A CGG + ++ G + SPS+P + + C WTI A G + L F
Sbjct: 439 PHWSSQEPICSA--PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFE 496
Query: 285 DFQMEEKYDYLEIEGSEPPTI-----WLSGMNIP-PPIISNKNWLRLHFVTDSNHRYRGF 338
+ +K D + + + L ++P ++S N +R+ F +D
Sbjct: 497 RLLLHDK-DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSD-------- 547
Query: 339 SAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSD- 397
Q + A F R F +G C +P +NG SD
Sbjct: 548 ----QARAASTFNIR-------------FEAFEKGH-------CYEP-YIQNGNFTTSDP 582
Query: 398 -FSLGSTVQFSCDEDYVL-QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTF 455
+++G+ V+F+CD + L QG I C + + + W+D P+C+ CG L +G
Sbjct: 583 TYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WNDTEPLCRA-MCGGELSAVAGVV 639
Query: 456 TSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQ 515
SPN+P Y C+W I V K I ++ + +L D LTI DG EV P + Q
Sbjct: 640 LSPNWPEPYVEGEDCIWKI-HVGEEKRIFLDIQFLNLS-NSDILTIYDGDEV-MPHILGQ 696
Query: 516 VLTGSFVPDLIVSMSSQMWLHLQTDESVGSV-----GFKVNYKEIEK-ESCGDPGTPLYG 569
L G+ P + S + + + +D + G + GF +NY E+ + +SC D L
Sbjct: 697 YL-GNSGPQKLYSSTPDLTIQFHSDPA-GLIFGKGQGFIMNYIEVSRNDSCSD----LPE 750
Query: 570 IREG-DGFSNRDVLR-----FECQFGFELIGEKSIVCQENNQWSANIPIC 613
I+ G S+ +++R ++C G++++G ++ CQ + WS++ P C
Sbjct: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Score = 100 bits (248), Expect = 3e-20
Identities = 97/397 (24%), Positives = 166/397 (41%), Gaps = 59/397 (14%)
Query: 65 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD 123
CGG + G + SP +P C W I A E ++ + F+ L ++ D ++++
Sbjct: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHS 510
Query: 124 GHPHPT-----NFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
G + + + +T F + S + + TSD A +A F + +E + C
Sbjct: 511 GQTNKSALLYDSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
Query: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLT-CIANSVNTASWDFPVPICR 236
P + +++G + ++C G+ L+ P + CI +V W+ P+CR
Sbjct: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCR 625
Query: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI-VAEPGDTISLIFTDFQMEEKYDYL 295
A CGG + +G++ SP++P Y DC W I V E IF D Q +L
Sbjct: 626 A--MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE----KRIFLDIQ------FL 673
Query: 296 EIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKA-----IDF 350
+ S+ TI+ G + P I+ +Y G S P ++ + I F
Sbjct: 674 NLSNSDILTIY-DGDEVMPHILG---------------QYLGNSGPQKLYSSTPDLTIQF 717
Query: 351 KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSC 408
S L GK + + + ++ C D E +NG + S L G+ + + C
Sbjct: 718 HSDPAGLIFGKGQGFIMNYIE----VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQC 773
Query: 409 DEDYVLQGAKSITCQRIAEVFAAWSDHRPVC-KVKTC 444
D Y + G+ ++TCQ +WS P C K+ C
Sbjct: 774 DPGYDIVGSDTLTCQ----WDLSWSSDPPFCEKIMYC 806
Score = 93.6 bits (231), Expect = 3e-18
Identities = 133/594 (22%), Positives = 216/594 (36%), Gaps = 72/594 (12%)
Query: 2704 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMCKV 2761
+SC P P G + + V F C++GY +QG C + WS P+C
Sbjct: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
Query: 2762 -----VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL-----ICQPN 2811
V+ + G + F T+ + + F +L + +
Sbjct: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
Query: 2812 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 2871
GQ +K ++ D P L E G+T+ T Q+ N
Sbjct: 511 GQTNK---SALLYDSLQTESVPFEGLLSE----GNTIRIEFTSD-----QARAASTFNIR 558
Query: 2872 WSGSQPHCSGDATGTCGDPGTP-GHGSRQESNFRTKSTVRYACDTGYILH-GSEERTCL- 2928
+ + G C +P G+ + + + + V + CD G+ L G C+
Sbjct: 559 FEAFEK-------GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECIN 611
Query: 2929 -ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGY-----ILSGPS 2982
+ W +P C+A+ CG G++ + G S + +EG I G
Sbjct: 612 VRDPYWNDTEPLCRAM-CG-------GELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE 663
Query: 2983 VRQCTANGTWSGTLPNCTIISCGDPGIP-ANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3041
R + + + I GD +P G G+ G Y P T++ +
Sbjct: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHSD 720
Query: 3042 RIRTCTINGTW--SGVMPTCRAVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELS 3097
G + R +C P+I NG T G I+Y C PGY++
Sbjct: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
Query: 3098 FPAVLTCVGNGTWSGEVPQCLP-KFCGDPGIPAQGKR--EGKSFIYQSEVSFSCNFPFIL 3154
LTC + +WS + P C +C DPG R + + + ++CN F+L
Sbjct: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
Query: 3155 VGSSTRICQADGT----WSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFH 3209
GSS C + T W+ PHC+ +C+NPG+P +G Q + G + F
Sbjct: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
Query: 3210 CKKGHLLQGSTTRTCL--PDLTWSGIQPEC------IPHSCKQPETPAHANVVG 3255
C +G L G T C+ W+G P C H+ + E A ++ G
Sbjct: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEG 954
Score = 82.0 bits (201), Expect = 9e-15
Identities = 133/599 (22%), Positives = 226/599 (37%), Gaps = 103/599 (17%)
Query: 2574 GTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2633
GT+ H + ++SC P +G+ G A F C LG+ L G+ + C+++
Sbjct: 380 GTFQLHYQA---FMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINA 436
Query: 2634 GL--WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD 2691
WS E C A G G+V+ +Y GS I
Sbjct: 437 SKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTN------------GSQFCI---- 480
Query: 2692 HNWSGQLPSCVPVSCGHPGSPIY---------GRTSGNGFNFNDVVTFSCNI-GYLMQGP 2741
W+ + P + ++ G+T+ + ++ + T S G L +G
Sbjct: 481 --WTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
Query: 2742 ------TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT-------YGT 2788
T Q +A ++ + +C +P I ++GNFT GT
Sbjct: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI----------QNGNFTTSDPTYNIGT 588
Query: 2789 VVFYDCNPGYFL-FGSSVLIC--QPNGQWDKPLPECIMIDCGHPGVPPNAVLS---GEKY 2842
+V + C+PG+ L G +++ C + W+ P C + G VLS E Y
Sbjct: 589 IVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPY 648
Query: 2843 TFGSTVHYSC-TGKRSLLGQSSRTCQLNGH-----WSGSQ--PHCSGDATGTCGDPGTPG 2894
G + G+ + + L+ + G + PH G G
Sbjct: 649 VEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG--------N 700
Query: 2895 HGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG--TTA 2952
G ++ + T+++ D ++ G + + + N R C + G TT+
Sbjct: 701 SGPQKLYSSTPDLTIQFHSDPAGLIFG-KGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTS 759
Query: 2953 NGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIISCGDPGIPA 3011
+ ++ R + + Y C GY + G C + +WS P C I+ C DPG
Sbjct: 760 HTELVR------GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVD 813
Query: 3012 NGLRYGDDYV--VGQNVSYMCQPGYTMELNGSRIRTCTINGT----WSGVMPTC---RAV 3062
+ R D V VG + Y C PG+ +E GS + TC T W+ +P C ++
Sbjct: 814 HSTRLISDPVLLVGTTIQYTCNPGFVLE--GSSLLTCYSRETGTPIWTSRLPHCVSEESL 871
Query: 3063 TCPTPPQISNGR--LEGTNFDWGFSISYICSPGYELSFPAVLTCV--GNGTWSGEVPQC 3117
C P NG L + G S++++C G+EL + C+ W+G +P C
Sbjct: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 76.3 bits (186), Expect = 5e-13
Identities = 114/533 (21%), Positives = 191/533 (35%), Gaps = 87/533 (16%)
Query: 2820 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 2876
+ M+ C P P + ++ G H+ C L G TC +N HWS +
Sbjct: 387 QAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTC-INASKPHWSSQE 445
Query: 2877 PHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGR 2936
P CS G + +T+ Y + + + C+ WT
Sbjct: 446 PICSAPCGGAVHN-----------------ATIGRVLSPSYPENTNGSQFCI----WTIE 484
Query: 2937 QPECKAVQCGNPGTTANGK--VFRIDGTTFSSSVIYSCM-------EGYILSGPSVR--- 2984
PE + + + K + G T S+++Y + EG + G ++R
Sbjct: 485 APEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEF 544
Query: 2985 ---QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVVGQNVSYMCQPGYTMELNG 3040
Q A T++ C +P I D Y +G V + C PG+++E
Sbjct: 545 TSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGP 604
Query: 3041 SRIRTCTINGT-WSGVMPTCRAVT---------CPTPPQISNGRLEGTNFDWGFSIS--- 3087
+ I + W+ P CRA+ P +EG + W +
Sbjct: 605 AIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEK 664
Query: 3088 --YICSPGYELSFPAVLTCVGNGTWSGE--VPQCLPKFCGDPGIPAQGKREGKSFIYQSE 3143
++ LS +LT + G+ +P L ++ G+ G +Y S
Sbjct: 665 RIFLDIQFLNLSNSDILTI-----YDGDEVMPHILGQYLGN---------SGPQKLYSST 710
Query: 3144 VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT-SCENPGVPRHGSQNNTFGFQV 3202
+ F G G G + IE ++ SC + ++G + + V
Sbjct: 711 PDLTIQFHSDPAGLIF------GKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELV 764
Query: 3203 -GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC--IPHSCKQPETPAHANVVGMDLP 3259
G+ + + C G+ + GS T TC DL+WS P C I + E ++ +
Sbjct: 765 RGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVL 824
Query: 3260 SHGYTLIYTCQPGFFLAGGTEHRVCRSDNT----WTGKVPICEAGSKILVKDP 3308
G T+ YTC PGF L G+ C S T WT ++P C + + +P
Sbjct: 825 LVGTTIQYTCNPGFVLE-GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
Score = 73.6 bits (179), Expect = 3e-12
Identities = 64/219 (29%), Positives = 95/219 (43%), Gaps = 30/219 (13%)
Query: 2589 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC-LA 2645
SC +LP NG K + T G+ + CD G+ +VGS C WS C
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 2646 GHCGIP-ELIVNGQVIGENYGYRDTVV-YQCNPGFRLIGSSVRICQQDHN----WSGQLP 2699
+C P E+ + ++I + T + Y CNPGF L GSS+ C W+ +LP
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 2700 SCV---PVSCGHPGSPIYGRTSGNGFNF--------NDVVTFSCNIGYLMQGPTKAQCQA 2748
CV ++C +PG P NG+ + +TF C G+ + G +C
Sbjct: 864 HCVSEESLACDNPGLP------ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL 917
Query: 2749 NR--QWSHPPPMCKVVNCSDPGI--PANSKRESKIEHGN 2783
+ W+ P P+CKV S A + E+ +E GN
Sbjct: 918 GQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGN 956
Score = 62.4 bits (150), Expect = 8e-09
Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 14/200 (7%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
CGG L + G + SP +P Y G +C W I E RI + Q L D L++YDG
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA----VSAHGFKVYYEEL-QSSSCG 179
+ + G P + S+ +++ SD A GF + Y E+ ++ SC
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
Query: 180 NPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
+ G T G +I Y C GY + G LTC + SW P C
Sbjct: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEK 802
Query: 238 EDAC--GGTMRGSSGIISSP 255
C G + S+ +IS P
Sbjct: 803 IMYCTDPGEVDHSTRLISDP 822
Score = 52.4 bits (124), Expect = 8e-06
Identities = 35/141 (24%), Positives = 59/141 (41%), Gaps = 13/141 (9%)
Query: 2443 LQWSADHGNNKKGFRIRYIAFYCSTPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGK 2501
L WS+D +K YC+ P H +IS + + +++ C+ GF L G
Sbjct: 791 LSWSSDPPFCEK-------IMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGS 843
Query: 2502 SSAVCRKSSYGYHAWDAPVPAC---QAISCGIPKAPTNGGILTTD--YLVGTRVTYFCND 2556
S C G W + +P C ++++C P P NG + YL G +T+ C +
Sbjct: 844 SLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYE 903
Query: 2557 GYRLSSKELTTAVCQSDGTWS 2577
G+ L + + W+
Sbjct: 904 GFELMGEVTIRCILGQPSHWN 924
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 174 QSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 231
+S +C NPG+P G +LY + G+ + + C G+ L G + CI + W+ P
Sbjct: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILG--QPSHWNGP 926
Query: 232 VPICR 236
+P+C+
Sbjct: 927 LPVCK 931
Score = 40.0 bits (92), Expect = 0.041
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 196 VGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
VG I+Y+C G++L+G LTC + T W +P C +E++
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEES 870
Score = 37.4 bits (85), Expect = 0.27
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 375 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 432
+ S C +PG PENG +I + G ++ F C E + L G +I C I + W
Sbjct: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHW 923
Query: 433 SDHRPVCKV 441
+ PVCKV
Sbjct: 924 NGPLPVCKV 932
Score = 35.4 bits (80), Expect = 1.0
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 556 EKESCGDPGTPL--YGIREGDGFSNRDVLRFECQFGFELIGEKSIVC--QENNQWSANIP 611
E +C +PG P Y I + + L F C GFEL+GE +I C + + W+ +P
Sbjct: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLP 928
Query: 612 IC 613
+C
Sbjct: 929 VC 930
Score = 35.4 bits (80), Expect = 1.0
Identities = 14/39 (35%), Positives = 22/39 (56%)
Query: 2312 GDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
G+ + + C GF L+G + C LG+ +G PVC+V
Sbjct: 894 GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
Score = 33.5 bits (75), Expect = 3.8
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 1793 GSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1833
G S+ F C G+ L G + IRC + + WN LP C V
Sbjct: 894 GESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 233 bits (594), Expect = 3e-60
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 1834 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1892
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 1893 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 1951
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 1952 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2011
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 2012 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2069
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 2070 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2128
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 2129 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2186
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 2187 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2246
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
Query: 2247 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2300
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
Query: 2301 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2334
E G ++ YQC PG+ +VG+++L C+
Sbjct: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
Score = 224 bits (570), Expect = 2e-57
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 1091 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1150
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
Query: 1151 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1209
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
Query: 1210 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1268
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
Query: 1269 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1328
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
Query: 1329 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1383
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Query: 1384 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1442
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1443 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1501
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1502 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1561
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1562 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1615
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1616 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1670
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1671 SPNYPKNYSVGHNC 1684
SP +P +V + C
Sbjct: 786 SPKFPVGATVQYIC 799
Score = 213 bits (543), Expect = 2e-54
Identities = 183/651 (28%), Positives = 293/651 (45%), Gaps = 58/651 (8%)
Query: 2031 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2085
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
Query: 2086 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2138
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
Query: 2139 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2197
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 2198 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2255
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 2256 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2314
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
Query: 2315 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2373
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
Query: 2374 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Query: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2484
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
Query: 2485 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2541
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
Query: 2542 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVIS---CGELPTPPN 2598
+ VG V Y C+ G+ L + T + G+ ++ P+C++ C L P N
Sbjct: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
Query: 2599 GNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCLA 2645
G + + + G+T F+C G++L G A +C+ WS+ C A
Sbjct: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 206 bits (525), Expect = 3e-52
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 790 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 847
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 848 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 906
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
Query: 907 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 964
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 965 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1023
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 1024 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1083
+ P + I L + +D S + G + + + C +P +
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
Query: 1084 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1140
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
Query: 1141 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1200
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
Query: 1201 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1257
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
Query: 1258 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1312
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
Query: 1313 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1371
E S R++S P +P C D G ++ + HD R P
Sbjct: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
Query: 1372 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
+D K + L P C P
Sbjct: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
Query: 1432 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1482
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
Score = 190 bits (482), Expect = 2e-47
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 444 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 502
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
Query: 503 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 618
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 619 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 677
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 678 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 734
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
Query: 735 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
Query: 794 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 853
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
Query: 854 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 909
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
Query: 910 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 964
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
Query: 965 GDVRGPSGTILSPGYP 980
GDV I SP +P
Sbjct: 775 GDVEHSRRLISSPKFP 790
Score = 184 bits (467), Expect = 1e-45
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 616 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
Query: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 733
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
Query: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
Query: 794 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 852
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 853 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 910
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
Query: 911 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 961
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
Query: 962 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1021
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
Query: 1022 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1075
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
Query: 1076 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
Query: 1134 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1192
+ S + P + E++ I S + G + I + F L +L
Sbjct: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
Query: 1193 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1252
+D + + S + + LE +L C
Sbjct: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
Query: 1253 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 183 bits (465), Expect = 2e-45
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 1483 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
Query: 1542 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1599
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
Query: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1659
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
Query: 1660 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1712
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
Query: 1713 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
Query: 1769 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1825
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
Query: 1826 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1885
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
Query: 1886 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 1945
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
Query: 1946 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 1998
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
Query: 1999 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2054
+P C + C G + +I SP FP C GF + S
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
Query: 2055 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
T HD ++GS + S P+ H S + S KQ H
Sbjct: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
Query: 2115 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
Query: 2175 CEA 2177
C A
Sbjct: 895 CRA 897
Score = 139 bits (351), Expect = 4e-32
Identities = 172/749 (22%), Positives = 279/749 (37%), Gaps = 123/749 (16%)
Query: 241 CGGTMRGSSGIISSP---SFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
C G G + SP S P + DC + I PG + +E K + +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDV--GLDCFFYISVYPG---------YGVEIKVQNISL 292
Query: 298 EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKL 357
E T+ G P P+ + LR + H+ A+ F+S
Sbjct: 293 REGETVTVEGLGGPDPLPLANQSFLLRGQVIRSPTHQ-----------AALRFQSLPPPA 341
Query: 358 FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA 417
PG + + + L C P P G + G + +F C Y L+GA
Sbjct: 342 GPGTFHFHYQAYLLS---------CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGA 392
Query: 418 KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITA 476
+ +TC + F W PVC + CG ++ + G SP FP Y +N C W++ A
Sbjct: 393 RHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEA 449
Query: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-DLIVSMSSQMWL 535
+ + ++FE+ L D L I +G V P V ++P + ++S ++
Sbjct: 450 PEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVYDSYEVEYLPIEGLLSSGKHFFV 507
Query: 536 HLQTDESVGSVGFKVNYKEIEKESCGDP---------GTPLYGIREGDGFSNRDVLRFEC 586
L TD S + G + Y+ ++ C +P TP Y + + F C
Sbjct: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV--------GTTVEFSC 559
Query: 587 QFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
G+ L G I C + + QW+ P C C T G VLSP++PE YG +C
Sbjct: 560 DPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDC 619
Query: 644 IWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
IW + + RI L + D L DGD + +LG ++G L ++ +
Sbjct: 620 IWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADV 678
Query: 704 RLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGIPINARRFGDNFQL--GSSISVI 755
++FQ+D S +GF I + N+ CP+ P IP N + +L G+ ++
Sbjct: 679 TIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIP-NGWKSPSQPELVHGTVVTYQ 737
Query: 756 CEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSL 815
C G+ + G+ + C + WS +P C H PG + S
Sbjct: 738 CYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSCHD------------PGDVEHSR 781
Query: 816 NCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYN-GTQVPQFLFSSS 874
+ G +++ ++ + +L HD GS + P+ L
Sbjct: 782 RLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ------AGSPKWSDRAPKCLLEQL 835
Query: 875 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDS 934
+ L +N + ++H T++ FSC
Sbjct: 836 KPCHGLSAPENGARSPEKQLHPAGATIH---------------------------FSCAP 868
Query: 935 GYRLSHEEPLLCEKNH--WWSHPLPTCDA 961
GY L + + C H WS P P C A
Sbjct: 869 GYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 127 bits (320), Expect = 1e-28
Identities = 138/569 (24%), Positives = 228/569 (40%), Gaps = 67/569 (11%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 122
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 123 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
G P P N L G + P +LR S + G ++ + SC
Sbjct: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
Query: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 299 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKS 352
+ PP + P ++S+ + TDS+ G + Y+ +
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQ------ 528
Query: 353 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDY 412
+G P + G +++ P +G+TV+FSCD Y
Sbjct: 529 QGHCYEP---------FVKYGNFSSSTPTYP----------------VGTTVEFSCDPGY 563
Query: 413 VL-QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCV 471
L QG+ I C + W++ P C+ C + +G SPN+P Y C+
Sbjct: 564 TLEQGSIIIEC--VDPHDPQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRGQDCI 620
Query: 472 WVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSS 531
W + V +K I ++ + G D LT DG ++ VL +G + + +
Sbjct: 621 WGV-HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL--TARVLGQYSGPRSHFKLFTSMA 676
Query: 532 QMWLHLQTDESVGSV----GFKVNYKEIEK-ESCGD-PGTPL-YGIREGDGFSNRDVLRF 584
+ + Q+D + GF +++ E+ + ++C + P P + + V+ +
Sbjct: 677 DVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTY 736
Query: 585 ECQFGFELIGEKSIVCQENNQWSANIPIC 613
+C G++++G ++CQ + WS ++P C
Sbjct: 737 QCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Score = 104 bits (260), Expect = 1e-21
Identities = 150/649 (23%), Positives = 239/649 (36%), Gaps = 108/649 (16%)
Query: 2380 CAWSISVEKGYNITMFVEFFQT-EKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNG 2438
C + ISV GY + + V+ E E ++ GP+ P+ ++ I S
Sbjct: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPD---PLPLANQSFLLRGQVIRSPT 327
Query: 2439 HEVFLQWSADHGNNKKG-FRIRYIAFY--CSTPESPPHGYIISQTGGQLNSVVRWACDRG 2495
H+ L++ + G F Y A+ C P P +G + + T R+ C G
Sbjct: 328 HQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDV-TVTSLHPGGSARFHCATG 386
Query: 2496 FRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCN 2555
++L G C ++ + WD+ P C A G+ + T G I++ + C+
Sbjct: 387 YQLKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCH 444
Query: 2556 ------DGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNK-----IGT 2604
+G RL ++ + D R ++ + + PP + +
Sbjct: 445 WLLEAPEGQRLHLHFEKVSLAEDDD---------RLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 2605 QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIV-NGQVIGEN 2663
+ S F +L G+A L + + GHC P + N
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ-------GHCYEPFVKYGNFSSSTPT 548
Query: 2664 YGYRDTVVYQCNPGFRLIGSSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPI 2713
Y TV + C+PG+ L S+ I C H+ W+ P+C V S G SP
Sbjct: 549 YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPN 608
Query: 2714 YGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPM 2758
+ G G + + +I L GP + Q+S P
Sbjct: 609 WPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSH 668
Query: 2759 CKVVNC---------SDPG----------------IPANSKRESKIEHGN---------F 2784
K+ SDPG +P N E N
Sbjct: 669 FKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL 728
Query: 2785 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEK 2841
+GTVV Y C PGY + GSSVL+CQ + W + LP C + C PG ++ ++S K
Sbjct: 729 VHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPK 788
Query: 2842 YTFGSTVHYSCTGKRSLLGQSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGS 2897
+ G+TV Y C L+G S TC + WS P C + C P +G+
Sbjct: 789 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 848
Query: 2898 R--QESNFRTKSTVRYACDTGYILHGSEERTCLAN--GSWTGRQPECKA 2942
R ++ +T+ ++C GY+L G C+ W+ P C+A
Sbjct: 849 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 104 bits (260), Expect = 1e-21
Identities = 104/410 (25%), Positives = 170/410 (41%), Gaps = 42/410 (10%)
Query: 62 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
Query: 121 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
Query: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 236
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
Query: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 296
A C G + S+G++ SP++P Y DC W + E I L D ++ L
Sbjct: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML---DIRV------LR 639
Query: 297 IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
I + T + G ++ ++ + R HF + F++ V I F+S
Sbjct: 640 IGPGDVLTFY-DGDDLTARVLGQYSGPRSHF--------KLFTSMADV--TIQFQSDPGT 688
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSCDEDYVL 414
G ++ CP+ E NG + S L G+ V + C Y +
Sbjct: 689 SVLGYQQGFVIHFFE----VPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQV 744
Query: 415 QGAKSITCQRIAEVFAAWSDHRPVC-KVKTC--GSNLQGPSGTFTSPNFP 461
G+ + CQ WS+ P C +V +C +++ +SP FP
Sbjct: 745 VGSSVLMCQ----WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 102 bits (254), Expect = 7e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 2179 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2234
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
Query: 2235 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2292
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
Query: 2293 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2352
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
Query: 2353 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2412
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2413 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2468
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 2469 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2528
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
Query: 2529 G 2529
G
Sbjct: 595 G 595
Score = 95.9 bits (237), Expect = 6e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 2886 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 2940
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
Query: 2941 -----------KAVQCGNPGTTANG-----------------------------KVFRID 2960
+ V G PG +N ++ +
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2961 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3010
G + +Y +EG + SG ++G +G G P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 3011 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3062
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
Query: 3063 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3099
C S G + N+ WG + PG L+F
Sbjct: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 3100 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3135
LT G +SG + +F DPG G ++G
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 3136 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3181
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
Query: 3182 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3236
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3237 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3289
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 3290 WTGKVPICEAGS 3301
W+ PIC A S
Sbjct: 888 WSDPPPICRAAS 899
Score = 74.7 bits (182), Expect = 2e-12
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 2589 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2645
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 2646 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQ----DHNWSGQLP 2699
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 2700 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2752
C+ C +P G S + FSC GY+++G +C W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 2753 SHPPPMCKVVN 2763
S PPP+C+ +
Sbjct: 889 SDPPPICRAAS 899
Score = 39.3 bits (90), Expect = 0.070
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 197 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 256
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
Score = 37.7 bits (86), Expect = 0.20
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 176 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 234 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 276
C E C G +G S P + + A T PG
Sbjct: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 233 bits (594), Expect = 3e-60
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 1834 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1892
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 1893 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 1951
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 1952 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2011
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 2012 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2069
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 2070 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2128
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 2129 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2186
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 2187 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2246
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
Query: 2247 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2300
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
Query: 2301 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2334
E G ++ YQC PG+ +VG+++L C+
Sbjct: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
Score = 224 bits (570), Expect = 2e-57
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 1091 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1150
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
Query: 1151 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1209
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
Query: 1210 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1268
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
Query: 1269 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1328
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
Query: 1329 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1383
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Query: 1384 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1442
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1443 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1501
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1502 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1561
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1562 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1615
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1616 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1670
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1671 SPNYPKNYSVGHNC 1684
SP +P +V + C
Sbjct: 786 SPKFPVGATVQYIC 799
Score = 213 bits (543), Expect = 2e-54
Identities = 183/651 (28%), Positives = 293/651 (45%), Gaps = 58/651 (8%)
Query: 2031 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2085
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
Query: 2086 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2138
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
Query: 2139 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2197
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 2198 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2255
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 2256 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2314
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
Query: 2315 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2373
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
Query: 2374 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Query: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2484
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
Query: 2485 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2541
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
Query: 2542 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVIS---CGELPTPPN 2598
+ VG V Y C+ G+ L + T + G+ ++ P+C++ C L P N
Sbjct: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
Query: 2599 GNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCLA 2645
G + + + G+T F+C G++L G A +C+ WS+ C A
Sbjct: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 206 bits (525), Expect = 3e-52
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 790 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 847
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 848 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 906
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
Query: 907 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 964
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 965 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1023
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 1024 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1083
+ P + I L + +D S + G + + + C +P +
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
Query: 1084 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1140
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
Query: 1141 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1200
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
Query: 1201 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1257
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
Query: 1258 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1312
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
Query: 1313 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1371
E S R++S P +P C D G ++ + HD R P
Sbjct: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
Query: 1372 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
+D K + L P C P
Sbjct: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
Query: 1432 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1482
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
Score = 190 bits (482), Expect = 2e-47
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 444 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 502
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
Query: 503 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 618
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
Query: 619 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 677
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 678 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 734
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
Query: 735 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
Query: 794 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 853
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
Query: 854 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 909
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
Query: 910 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 964
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
Query: 965 GDVRGPSGTILSPGYP 980
GDV I SP +P
Sbjct: 775 GDVEHSRRLISSPKFP 790
Score = 184 bits (467), Expect = 1e-45
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 616 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
Query: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 733
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
Query: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
Query: 794 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 852
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 853 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 910
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
Query: 911 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 961
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
Query: 962 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1021
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
Query: 1022 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1075
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
Query: 1076 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
Query: 1134 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1192
+ S + P + E++ I S + G + I + F L +L
Sbjct: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
Query: 1193 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1252
+D + + S + + LE +L C
Sbjct: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
Query: 1253 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 183 bits (465), Expect = 2e-45
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 1483 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
Query: 1542 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1599
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
Query: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1659
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
Query: 1660 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1712
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
Query: 1713 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
Query: 1769 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1825
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
Query: 1826 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1885
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
Query: 1886 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 1945
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
Query: 1946 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 1998
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
Query: 1999 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2054
+P C + C G + +I SP FP C GF + S
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
Query: 2055 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
T HD ++GS + S P+ H S + S KQ H
Sbjct: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
Query: 2115 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
Query: 2175 CEA 2177
C A
Sbjct: 895 CRA 897
Score = 139 bits (351), Expect = 4e-32
Identities = 172/749 (22%), Positives = 279/749 (37%), Gaps = 123/749 (16%)
Query: 241 CGGTMRGSSGIISSP---SFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
C G G + SP S P + DC + I PG + +E K + +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDV--GLDCFFYISVYPG---------YGVEIKVQNISL 292
Query: 298 EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKL 357
E T+ G P P+ + LR + H+ A+ F+S
Sbjct: 293 REGETVTVEGLGGPDPLPLANQSFLLRGQVIRSPTHQ-----------AALRFQSLPPPA 341
Query: 358 FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA 417
PG + + + L C P P G + G + +F C Y L+GA
Sbjct: 342 GPGTFHFHYQAYLLS---------CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGA 392
Query: 418 KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITA 476
+ +TC + F W PVC + CG ++ + G SP FP Y +N C W++ A
Sbjct: 393 RHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEA 449
Query: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-DLIVSMSSQMWL 535
+ + ++FE+ L D L I +G V P V ++P + ++S ++
Sbjct: 450 PEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVYDSYEVEYLPIEGLLSSGKHFFV 507
Query: 536 HLQTDESVGSVGFKVNYKEIEKESCGDP---------GTPLYGIREGDGFSNRDVLRFEC 586
L TD S + G + Y+ ++ C +P TP Y + + F C
Sbjct: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV--------GTTVEFSC 559
Query: 587 QFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
G+ L G I C + + QW+ P C C T G VLSP++PE YG +C
Sbjct: 560 DPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDC 619
Query: 644 IWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
IW + + RI L + D L DGD + +LG ++G L ++ +
Sbjct: 620 IWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADV 678
Query: 704 RLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGIPINARRFGDNFQL--GSSISVI 755
++FQ+D S +GF I + N+ CP+ P IP N + +L G+ ++
Sbjct: 679 TIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIP-NGWKSPSQPELVHGTVVTYQ 737
Query: 756 CEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSL 815
C G+ + G+ + C + WS +P C H PG + S
Sbjct: 738 CYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSCHD------------PGDVEHSR 781
Query: 816 NCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYN-GTQVPQFLFSSS 874
+ G +++ ++ + +L HD GS + P+ L
Sbjct: 782 RLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ------AGSPKWSDRAPKCLLEQL 835
Query: 875 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDS 934
+ L +N + ++H T++ FSC
Sbjct: 836 KPCHGLSAPENGARSPEKQLHPAGATIH---------------------------FSCAP 868
Query: 935 GYRLSHEEPLLCEKNH--WWSHPLPTCDA 961
GY L + + C H WS P P C A
Sbjct: 869 GYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 127 bits (320), Expect = 1e-28
Identities = 138/569 (24%), Positives = 228/569 (40%), Gaps = 67/569 (11%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 122
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
Query: 123 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
G P P N L G + P +LR S + G ++ + SC
Sbjct: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
Query: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 299 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKS 352
+ PP + P ++S+ + TDS+ G + Y+ +
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQ------ 528
Query: 353 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDY 412
+G P + G +++ P +G+TV+FSCD Y
Sbjct: 529 QGHCYEP---------FVKYGNFSSSTPTYP----------------VGTTVEFSCDPGY 563
Query: 413 VL-QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCV 471
L QG+ I C + W++ P C+ C + +G SPN+P Y C+
Sbjct: 564 TLEQGSIIIEC--VDPHDPQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRGQDCI 620
Query: 472 WVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSS 531
W + V +K I ++ + G D LT DG ++ VL +G + + +
Sbjct: 621 WGV-HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL--TARVLGQYSGPRSHFKLFTSMA 676
Query: 532 QMWLHLQTDESVGSV----GFKVNYKEIEK-ESCGD-PGTPL-YGIREGDGFSNRDVLRF 584
+ + Q+D + GF +++ E+ + ++C + P P + + V+ +
Sbjct: 677 DVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTY 736
Query: 585 ECQFGFELIGEKSIVCQENNQWSANIPIC 613
+C G++++G ++CQ + WS ++P C
Sbjct: 737 QCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Score = 104 bits (260), Expect = 1e-21
Identities = 150/649 (23%), Positives = 239/649 (36%), Gaps = 108/649 (16%)
Query: 2380 CAWSISVEKGYNITMFVEFFQT-EKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNG 2438
C + ISV GY + + V+ E E ++ GP+ P+ ++ I S
Sbjct: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPD---PLPLANQSFLLRGQVIRSPT 327
Query: 2439 HEVFLQWSADHGNNKKG-FRIRYIAFY--CSTPESPPHGYIISQTGGQLNSVVRWACDRG 2495
H+ L++ + G F Y A+ C P P +G + + T R+ C G
Sbjct: 328 HQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDV-TVTSLHPGGSARFHCATG 386
Query: 2496 FRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCN 2555
++L G C ++ + WD+ P C A G+ + T G I++ + C+
Sbjct: 387 YQLKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCH 444
Query: 2556 ------DGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNK-----IGT 2604
+G RL ++ + D R ++ + + PP + +
Sbjct: 445 WLLEAPEGQRLHLHFEKVSLAEDDD---------RLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 2605 QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIV-NGQVIGEN 2663
+ S F +L G+A L + + GHC P + N
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ-------GHCYEPFVKYGNFSSSTPT 548
Query: 2664 YGYRDTVVYQCNPGFRLIGSSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPI 2713
Y TV + C+PG+ L S+ I C H+ W+ P+C V S G SP
Sbjct: 549 YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPN 608
Query: 2714 YGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPM 2758
+ G G + + +I L GP + Q+S P
Sbjct: 609 WPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSH 668
Query: 2759 CKVVNC---------SDPG----------------IPANSKRESKIEHGN---------F 2784
K+ SDPG +P N E N
Sbjct: 669 FKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL 728
Query: 2785 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEK 2841
+GTVV Y C PGY + GSSVL+CQ + W + LP C + C PG ++ ++S K
Sbjct: 729 VHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPK 788
Query: 2842 YTFGSTVHYSCTGKRSLLGQSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGS 2897
+ G+TV Y C L+G S TC + WS P C + C P +G+
Sbjct: 789 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 848
Query: 2898 R--QESNFRTKSTVRYACDTGYILHGSEERTCLAN--GSWTGRQPECKA 2942
R ++ +T+ ++C GY+L G C+ W+ P C+A
Sbjct: 849 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 104 bits (260), Expect = 1e-21
Identities = 104/410 (25%), Positives = 170/410 (41%), Gaps = 42/410 (10%)
Query: 62 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
Query: 121 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
Query: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 236
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
Query: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 296
A C G + S+G++ SP++P Y DC W + E I L D ++ L
Sbjct: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML---DIRV------LR 639
Query: 297 IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
I + T + G ++ ++ + R HF + F++ V I F+S
Sbjct: 640 IGPGDVLTFY-DGDDLTARVLGQYSGPRSHF--------KLFTSMADV--TIQFQSDPGT 688
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSCDEDYVL 414
G ++ CP+ E NG + S L G+ V + C Y +
Sbjct: 689 SVLGYQQGFVIHFFE----VPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQV 744
Query: 415 QGAKSITCQRIAEVFAAWSDHRPVC-KVKTC--GSNLQGPSGTFTSPNFP 461
G+ + CQ WS+ P C +V +C +++ +SP FP
Sbjct: 745 VGSSVLMCQ----WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 102 bits (254), Expect = 7e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 2179 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2234
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
Query: 2235 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2292
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
Query: 2293 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2352
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
Query: 2353 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2412
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2413 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2468
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 2469 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2528
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
Query: 2529 G 2529
G
Sbjct: 595 G 595
Score = 95.9 bits (237), Expect = 6e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 2886 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 2940
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
Query: 2941 -----------KAVQCGNPGTTANG-----------------------------KVFRID 2960
+ V G PG +N ++ +
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2961 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3010
G + +Y +EG + SG ++G +G G P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 3011 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3062
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
Query: 3063 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3099
C S G + N+ WG + PG L+F
Sbjct: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 3100 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3135
LT G +SG + +F DPG G ++G
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 3136 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3181
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
Query: 3182 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3236
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3237 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3289
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 3290 WTGKVPICEAGS 3301
W+ PIC A S
Sbjct: 888 WSDPPPICRAAS 899
Score = 74.7 bits (182), Expect = 2e-12
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 2589 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2645
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 2646 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQ----DHNWSGQLP 2699
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 2700 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2752
C+ C +P G S + FSC GY+++G +C W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 2753 SHPPPMCKVVN 2763
S PPP+C+ +
Sbjct: 889 SDPPPICRAAS 899
Score = 39.3 bits (90), Expect = 0.070
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 197 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 256
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
Score = 37.7 bits (86), Expect = 0.20
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 176 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 234 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 276
C E C G +G S P + + A T PG
Sbjct: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 218 bits (555), Expect = 8e-56
Identities = 201/831 (24%), Positives = 329/831 (39%), Gaps = 191/831 (22%)
Query: 436 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE-- 493
R + + CG LQ +G +SP FP Y S C+W ++ K++ +NF DL
Sbjct: 341 RKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIV-LNFTTMDLYKS 399
Query: 494 --IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
YD + + DG P +L G +P+++ S S+MW+ ++ + GF
Sbjct: 400 SLCWYDYIEVRDGYWRKSP--LLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAV 457
Query: 552 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 611
Y+ I CG IR+ +G
Sbjct: 458 YEAI----CGGE------IRKNEG------------------------------------ 471
Query: 612 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 667
+ SP+YP+ Y C+W I + L+F F++E
Sbjct: 472 ---------------QIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCA 516
Query: 668 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 727
+D+L V+DG S SP++G F G + P + S S+ L ++F +D +++ GF +
Sbjct: 517 YDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK-EE 575
Query: 728 NECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
+EC P R G CE+ + T G+ C + C
Sbjct: 576 DECAKPD------RGG------------CEQRCLNTLGSYQCAC---EPGYELGPDRRSC 614
Query: 788 GAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YD 843
A CGG + +G I +PGWP Y + NC W + A + I + FE F+ E N YD
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 844 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 903
+E+ G + S L G + G +VP+ + S N + + F +DN+ S GFK H+
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF------- 727
Query: 904 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 963
+S D +G + + C +G+ L H+ C+ +A C
Sbjct: 728 FSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVL-HDNKHDCK------------EAEC 774
Query: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1019
+ PSG I SP +P+ YP+ CTW + T G ++ F F +E H +D+L +
Sbjct: 775 EQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEV 834
Query: 1020 TENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1078
+ + P L RL G+ +P + A GN + +RF+SD S+ +GF
Sbjct: 835 FDGETEKSPILGRLCGNKIPDPLVA--TGN-KMFVRFVSDASVQRKGFQ----------- 880
Query: 1079 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1138
T S G RL+ S+ PR +
Sbjct: 881 ---------------------ATHSTECGGRLKAESK---------------PRDLYSHA 904
Query: 1139 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1193
NN Y +C + + + G + +S +TF + + D ++++
Sbjct: 905 QFGDNN------------YPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELF 952
Query: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
DG D T LG F G+ + S + + + F++D +GF + Y S
Sbjct: 953 DGLDSTAVGLGRFCGSGPPE-EIYSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 206 bits (523), Expect = 4e-52
Identities = 177/662 (26%), Positives = 279/662 (42%), Gaps = 144/662 (21%)
Query: 1308 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1363
A CGG + ++ G+I SP YP Y C+W I V V L F +F+ E ++D
Sbjct: 460 AICGGEIR-KNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 1364 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1423
L V DG EN L+ G PE I ST N + ++F +D ++K+GFA F
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKE-EDE 577
Query: 1424 CRDPGVPMNGTRNGDGREPGDTV---VFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
C P R G + +T+ C+PGYEL + R C
Sbjct: 578 CAKPD------RGGCEQRCLNTLGSYQCACEPGYELGPDRRS-----------------C 614
Query: 1481 IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YD 1536
A CGG LT +G I +P +P YP +++C W + Y IS+ F F +E N YD
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1537 FLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRES 1596
++ I+ G S S L G F +++PE I S N M + F+SD +VS GF + + E
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1597 CFDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1653
D G G ++ +T+ Y C G+VL +
Sbjct: 735 SKDNG--------GCQHECVNTMGSYMCQCRNGFVLH-----------------DNKHDC 769
Query: 1654 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSI-AVPKEFV--VFGQFVF--FQTSLH 1708
A C + G + SPN+P Y C + I A P + F +F Q +
Sbjct: 770 KEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAY 829
Query: 1709 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
D +EV+DG T++S +L L G+ + L +++GN++ +RF S + KGF
Sbjct: 830 DHLEVFDGETEKSPILGRLCGNKIPDPL-VATGNKMFVRFVSDASVQRKGFQ-------A 881
Query: 1769 TSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL---AQWN 1825
T ST+C GR ++ E+ P L AQ+
Sbjct: 882 THSTECG-------GR---------------------------LKAESKPRDLYSHAQFG 907
Query: 1826 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEH- 1884
D+ Y ++C W + G+ +++ +F E
Sbjct: 908 DN--------------------------NYPGQVDCEWLLVSERGSRLELSFQTFEVEEE 941
Query: 1885 ---NWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 1941
+D ++ +DG D+ A LG + G+ P + S +++ ++F +D +++ GFH+ Y
Sbjct: 942 ADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYK 1001
Query: 1942 AI 1943
+I
Sbjct: 1002 SI 1003
Score = 197 bits (500), Expect = 2e-49
Identities = 154/510 (30%), Positives = 227/510 (44%), Gaps = 76/510 (14%)
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
A CGG + + G I SPN+P Y ++C W ITV+ Y + L F SF IE + YD+
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
L + DG NSPLIG F PE I S+SNT+ + F SDG+V+ GF + K + C
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF-FKEEDEC 578
Query: 1598 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
P R G + + +T+ Y C+ GY L G D R SC
Sbjct: 579 AKP------DRGGCEQRCLNTLGSYQCACEPGYEL----------GPDRR--------SC 614
Query: 1655 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFF-----QTSLHD 1709
A CG T GT+ +P +PK Y NCV+ + P ++ + +F FF + +D
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1710 VVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1767
VE++ G + +S L G+ E + S N + I F S ++ KGF HF
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVI-TSQFNNMRIEFKSDNTVSKKGFKAHFF----- 728
Query: 1768 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1827
+ +CS + G + +G S + C G++LH D+
Sbjct: 729 -SDKDECS---KDNGGCQHECVNTMG-SYMCQCRNGFVLH------------------DN 765
Query: 1828 LPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1885
C C + G I SP +P+ Y + C W+I+ G I++ F E +
Sbjct: 766 KHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQ 825
Query: 1886 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY-T 1941
+D L+ +DG +P LG G IP L +T N +++ F SD SV GF + T
Sbjct: 826 ECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885
Query: 1942 AIG--LDSCPEPQTPSSGIKIGDRYMVGDV 1969
G L + +P+ S + GD G V
Sbjct: 886 ECGGRLKAESKPRDLYSHAQFGDNNYPGQV 915
Score = 187 bits (476), Expect = 1e-46
Identities = 172/680 (25%), Positives = 273/680 (40%), Gaps = 159/680 (23%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CGG ++ G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
+ DG + R G+ P + ST + ++ SD V+ GF + + + C
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK-EEDECAK 580
Query: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
P +G + + +C GY L G + +C E A
Sbjct: 581 PD---RGGCEQRCLNTLGSYQCACEPGYEL-GPDRRSC-------------------EAA 617
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYLE 296
CGG + +G I++P +P EY N +C W +VA IS+ F F++E KYDY+E
Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVE 677
Query: 297 IEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKS 352
I L G +P I S N +R+ F +D+ +GF A +
Sbjct: 678 IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF---------- 727
Query: 353 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDY 412
F KD +K + GG + E +GS C +
Sbjct: 728 -----FSDKDECSK----DNGGC-----------QHECVNTMGS-------YMCQCRNGF 760
Query: 413 VLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVW 472
VL D++ CK C + PSG TSPN+P +Y S +C W
Sbjct: 761 VLH------------------DNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTW 802
Query: 473 VITAVNTNKVIQINFEEFDL----EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVS 528
I+A ++ I++ F EF++ E YD L + DG P +L L G+ +PD +V+
Sbjct: 803 EISATPGHR-IKLAFSEFEIEQHQECAYDHLEVFDGETEKSP--ILGRLCGNKIPDPLVA 859
Query: 529 MSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQF 588
++M++ +D SV GF+ + CG G + D +S+ QF
Sbjct: 860 TGNKMFVRFVSDASVQRKGFQATH----STECG--GRLKAESKPRDLYSH-------AQF 906
Query: 589 GFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTII 648
G +NN Y ++C W ++
Sbjct: 907 G------------DNN--------------------------------YPGQVDCEWLLV 922
Query: 649 SDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILR 704
S+ GSR+ LSF F++E + +D++ + DG + LG F G+ P + S +
Sbjct: 923 SERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVL 982
Query: 705 LEFQADHSMSGRGFNITYNT 724
+ F D +++ +GF+I Y +
Sbjct: 983 IHFHTDDTINKKGFHIRYKS 1002
Score = 183 bits (464), Expect = 3e-45
Identities = 141/501 (28%), Positives = 219/501 (43%), Gaps = 62/501 (12%)
Query: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1710
A CG +EG + SPNYP +Y CV+ I V + + V F F+ HD
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
+EV DG ++ S L+ G E + S+ N + ++F S G + GF +
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIR-STSNTLWMKFVSDGTVNKAGFAANFFK----E 574
Query: 1771 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
+C+ +R N S C PGY L +
Sbjct: 575 EDECAKPDRGGCEQRCLNTLG---SYQCACEPGYEL------------------GPDRRS 613
Query: 1831 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1886
C CGG+LTK GTI +PG+P+ Y N NCVW++ P I V+ F E N +
Sbjct: 614 CEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKY 673
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946
D ++ + G + + G + G +P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 674 DYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKD 732
Query: 1947 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2006
C + + G + +G + QC G+ L + H C A+
Sbjct: 733 ECSK---DNGGCQHECVNTMGSYMC-QCRNGFVLHDNKH-DCKE--------------AE 773
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLE 2062
C + SG+I SP +P YPS +CTW I+ G + L F F E +D+LE
Sbjct: 774 CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAY---QLQS 2119
V G +E S ++GRL G +IP L +T ++ + F SD S ++GF + +L++
Sbjct: 834 VFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKA 893
Query: 2120 CPDPRPFRNGFVIGNDFTVGQ 2140
PR + G++ GQ
Sbjct: 894 ESKPRDLYSHAQFGDNNYPGQ 914
Score = 181 bits (458), Expect = 1e-44
Identities = 142/469 (30%), Positives = 217/469 (46%), Gaps = 64/469 (13%)
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
A CGG + G I SP +P +Y +C W I + + V L F +F E +DY
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
LEVR G+SE S +IGR G P + ST++ + F SD + NK GF + + +
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECA 579
Query: 2121 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
+P R G T+G + C PGY L G R CEA CG
Sbjct: 580 ---KPDRGGCEQRCLNTLG-SYQCACEPGYEL----------GPDRR------SCEAACG 619
Query: 2181 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2236
G +T +NGTI +PG+P EYP ++C W V P I + F + E YD++ +W
Sbjct: 620 GLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIW 679
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQPP 2294
G S G+F G E + S N + I+F SD T S GF
Sbjct: 680 SGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGF---------------- 723
Query: 2295 PPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCP 2353
A ++ DE + +++C+ +G+ + CR G L D + C
Sbjct: 724 ----KAHFFSDKDECSKDNGGCQHECV---NTMGSYMCQCRNGFVLH-DNKHDCKEAEC- 774
Query: 2354 ANELRLDS-TGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2408
E ++ S +G+I SP +PD YP+ + C W IS G+ I + F+ E+ +D L
Sbjct: 775 --EQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 2409 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2457
+V+DG +SP+L L G+ + + G+++F+++ +D +KGF+
Sbjct: 833 EVFDGETEKSPILGRLCGN-KIPDPLVATGNKMFVRFVSDASVQRKGFQ 880
Score = 177 bits (450), Expect = 1e-43
Identities = 174/686 (25%), Positives = 278/686 (40%), Gaps = 165/686 (24%)
Query: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YD 293
E CGG +R + G I SP++P++Y +C W I + L F F++E YD
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 294 YLEIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
YLE+ + P G + P I S N L + FV+D GF+A +
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF------- 571
Query: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
F +D K PD G E +R + +LGS Q +C+
Sbjct: 572 --------FKEEDECAK----------------PDRGGCE--QRCLN--TLGS-YQCACE 602
Query: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Y L G +C+ CG L +GT T+P +P +Y N
Sbjct: 603 PGYEL-GPDRRSCEA------------------ACGGLLTKLNGTITTPGWPKEYPPNKN 643
Query: 470 CVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDL 525
CVW + A T I + FE F+LE YD + I G + + G+ VP++
Sbjct: 644 CVWQVVAP-TQYRISVKFEFFELEGNEVCKYDYVEIWSG--LSSESKLHGKFCGAEVPEV 700
Query: 526 IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFE 585
I S + M + ++D +V GFK ++ +K+ C G + + + +
Sbjct: 701 ITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKDECSKDN----GGCQHECVNTMGSYMCQ 755
Query: 586 CQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIW 645
C+ GF L K C+E C +P G + SP++P+ Y + C W
Sbjct: 756 CRNGFVLHDNKHD-CKEAE------------CEQKIHSPSGLITSPNWPDKYPSRKECTW 802
Query: 646 TIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 701
I + PG RI L+F++F++E +D L V DG++ +SPILG G
Sbjct: 803 EISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCG------------ 850
Query: 702 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 761
N+ PDP + + F F +S+ +GF
Sbjct: 851 --------------------------NKIPDPLVATGNKMFV-RFVSDASVQ---RKGFQ 880
Query: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV--ILSPGWPG--YYKDSLNC 817
T TE CGG A S + S G Y ++C
Sbjct: 881 ATHSTE-----------------------CGGRLKAESKPRDLYSHAQFGDNNYPGQVDC 917
Query: 818 EWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSS 873
EW++ +E G ++++F+ F+ E YD +E+ DG + + LG + G+ P+ ++S
Sbjct: 918 EWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSI 977
Query: 874 SNFIYLLFTTDNSRSNNGFKIHYESV 899
+ + + F TD++ + GF I Y+S+
Sbjct: 978 GDSVLIHFHTDDTINKKGFHIRYKSI 1003
Score = 166 bits (419), Expect = 5e-40
Identities = 184/725 (25%), Positives = 282/725 (38%), Gaps = 169/725 (23%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CG TL+ NG + SPGFP GYP+ +C W + +I + F + L + YDY+
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
+ DG+ + R G LP +TST S + S GF YE + CG
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI----CGG 464
Query: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
+G + Y D P C+ W V +E
Sbjct: 465 EIRKNEGQIQS--------------PNYPDDYRPMKECV--------WKITV----SESY 498
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG- 299
G ++ SF E H+N YDYLE+
Sbjct: 499 HVG--------LTFQSFEIERHDNC-------------------------AYDYLEVRDG 525
Query: 300 ---SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
+ P G + P I S N L + FV+D GF+A +
Sbjct: 526 TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF-------------- 571
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
F +D K PD G E +R + +LGS Q +C+ Y L G
Sbjct: 572 -FKEEDECAK----------------PDRGGCE--QRCLN--TLGS-YQCACEPGYEL-G 608
Query: 417 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 476
+C+ CG L +GT T+P +P +Y N CVW + A
Sbjct: 609 PDRRSCE------------------AACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVA 650
Query: 477 VNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ 532
T I + FE F+LE YD + I G + + G+ VP++I S +
Sbjct: 651 -PTQYRISVKFEFFELEGNEVCKYDYVEIWSG--LSSESKLHGKFCGAEVPEVITSQFNN 707
Query: 533 MWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFEL 592
M + ++D +V GFK ++ +K+ C G + + + +C+ GF L
Sbjct: 708 MRIEFKSDNTVSKKGFKAHFFS-DKDECSKDN----GGCQHECVNTMGSYMCQCRNGFVL 762
Query: 593 IGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPG 652
K C+E C +P G + SP++P+ Y + C W I + PG
Sbjct: 763 HDNKH-DCKEAE------------CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPG 809
Query: 653 SRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 708
RI L+F++F++E +D L V DG++ +SPILG G ++P L + + + + F
Sbjct: 810 HRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFV 869
Query: 709 ADHSMSGRGFNITYNTFGHNEC-------PDPGIPINARRFGDNFQLGSSISVICEEGFI 761
+D S+ +GF T++T EC P + +FGDN G V CE +
Sbjct: 870 SDASVQRKGFQATHST----ECGGRLKAESKPRDLYSHAQFGDNNYPG---QVDCEWLLV 922
Query: 762 KTQGT 766
+G+
Sbjct: 923 SERGS 927
Score = 150 bits (379), Expect = 2e-35
Identities = 130/501 (25%), Positives = 207/501 (41%), Gaps = 63/501 (12%)
Query: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
+A+CGG++R G I SP YP+ Y C W + V+ V F +F +E H +D
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
YL + + S PL R G D P I + + ++F+SD +++ GF F +
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRS---TSNTLWMKFVSDGTVNKAGFAANFFKEE 575
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
+ C P R G + +C GY LG RR C
Sbjct: 576 -DECAKPDRGGCEQRCLNTLG---SYQCACEPGYE---------LGPDRR-------SCE 615
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
A CG T G + +P +P Y N C++ + I++ F L +V K
Sbjct: 616 AACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDY 675
Query: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
I+ G + L G F GA + + ++S N + +EF SD + +GF+ + S +
Sbjct: 676 VEIWSGLSSESKLHGKFCGAEVPEV-ITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1309
+D G Q ++ G + + C G+ LH D AE
Sbjct: 735 SKDNGGCQHEC-VNTMGSY-----MCQCRNGFVLH---------------DNKHDCKEAE 773
Query: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHDIL 1365
C + SG I SP +P Y + C W I PG+ + L F F+ E ++D L
Sbjct: 774 CEQKIH-SPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 1366 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACR 1425
V+DG E +L + G+ IP+ + +T N + ++F +D + + GF S+ +
Sbjct: 833 EVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLK 892
Query: 1426 DPGVP---MNGTRNGDGREPG 1443
P + + GD PG
Sbjct: 893 AESKPRDLYSHAQFGDNNYPG 913
Score = 115 bits (287), Expect = 1e-24
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 46/302 (15%)
Query: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
EA+CGG I G I SP YPD+Y ++C W + V + + F + E YD
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQLR 2289
++ V DG +NSP IG+F G E + STSN + +KF SD T +GF
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGF----------- 567
Query: 2290 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2347
A E+DE D +CL +G+ C G L D
Sbjct: 568 ---------AANFFKEEDECAKPDRGGCEQRCL---NTLGSYQCACEPGYELGPDRRS-- 613
Query: 2348 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2403
C+ C +L+ G I +PG+P YP + C W + Y I++ EFF+ E
Sbjct: 614 CEAACGGLLTKLN--GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVC 671
Query: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
++D ++++ G + +S L G + A ITS + + +++ +D+ +KKGF+ +
Sbjct: 672 KYDYVEIWSGLSSES----KLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF 727
Query: 2461 IA 2462
+
Sbjct: 728 FS 729
Score = 77.0 bits (188), Expect = 3e-13
Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
L RC A CG + NG + SPG+P+ YP++ C W V V PG I +NFT +
Sbjct: 343 LYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL 401
Query: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS 2271
YD+I V DG + SP +G+F G+ E + ST +++ I+F S
Sbjct: 402 CWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRS 445
Score = 70.1 bits (170), Expect = 4e-11
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
CG + + +G + SPGFP YPS C W +++ G + L F S+ +DY+E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
VR G S ++GR G ++P L ST + F S + +GF VY+A
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 68.6 bits (166), Expect = 1e-10
Identities = 39/112 (34%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CG L S+G + SP FP+ YP C W ++V I L F + + + YD++
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
+ DG SPL+G F KLPE + S+ + M + FRS + GF Y+A
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 65.5 bits (158), Expect = 9e-10
Identities = 39/131 (29%), Positives = 68/131 (51%), Gaps = 5/131 (3%)
Query: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
L G + + + +C A CG +G + SPG+P Y +C W + PG I +
Sbjct: 332 LSKGDIAQARKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLN 390
Query: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
F + +++ L YD +EV DG SPLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 391 FTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWV 450
Query: 889 NNGFKIHYESV 899
GF YE++
Sbjct: 451 GKGFAAVYEAI 461
Score = 64.7 bits (156), Expect = 2e-09
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 10/116 (8%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-------WD 1887
CG L + G + SPG+P Y + +C+W+++V G I V++F T +D
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKI---VLNFTTMDLYKSSLCWYD 405
Query: 1888 SLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
++ DG +P LG + G +P +L ST + +++ F+S + GF Y AI
Sbjct: 406 YIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
Score = 63.2 bits (152), Expect = 5e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 8/112 (7%)
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
ACG T++ S+G +SSP FPN Y + C W + PG+ I L FT + + YDY+
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407
Query: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
E+ P G +P + S + + + F + SN +GF+A Y+
Sbjct: 408 EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYE 459
Score = 62.8 bits (151), Expect = 6e-09
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 2026 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2081
NYP +DC W + G + L F F E +DY+E+ G T+ +GR G
Sbjct: 910 NYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSG 969
Query: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
P ++S ++FH+D + NK+GFHI Y++
Sbjct: 970 PPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 57.0 bits (136), Expect = 3e-07
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 9/122 (7%)
Query: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
Y P+C G ES+G + SPG+P Y + C+W + V PG + L F D
Sbjct: 344 YRCPAC-----GETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYK 398
Query: 1361 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1416
S +D + V DG LL G +PE + ST + + I+F + GFA +
Sbjct: 399 SSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458
Query: 1417 SS 1418
+
Sbjct: 459 EA 460
Score = 57.0 bits (136), Expect = 3e-07
Identities = 34/112 (30%), Positives = 58/112 (51%), Gaps = 10/112 (8%)
Query: 2179 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2230
CGG + A + +YS + YP DC WL+ G+ + ++F + E Y
Sbjct: 887 CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946
Query: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFV 2280
D++ ++DG D + +G+F G+ E +YS + +LI FH+D T + GF +
Sbjct: 947 DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHI 998
Score = 54.7 bits (130), Expect = 2e-06
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query: 59 KGFIYT----CGGTLKGLNGTIESPGFPY----GYPNGANCTWVIIAEERNRIQIVFQSF 110
KGF T CGG LK + + YP +C W++++E +R+++ FQ+F
Sbjct: 877 KGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTF 936
Query: 111 ALEEE----YDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF 166
+EEE YDY+ L+DG R G P + S + +D ++ GF
Sbjct: 937 EVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGF 996
Query: 167 KVYYEELQ 174
+ Y+ ++
Sbjct: 997 HIRYKSIR 1004
Score = 53.1 bits (126), Expect = 5e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
R L C A CG S G + SP +P Y +C++ ++V P E +V F +++
Sbjct: 341 RKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKS 399
Query: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
SL +D +EV DG ++S LL G E L S+ +++ I F S KGF VY
Sbjct: 400 SLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVL-TSTDSRMWIEFRSSSNWVGKGFAAVY 458
Query: 1764 QAV 1766
+A+
Sbjct: 459 EAI 461
Score = 50.4 bits (119), Expect = 3e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
CPA E +S G + SPG+P+ YP+ C W +SV G I + K +D
Sbjct: 346 CPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYD 405
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
++V DG +SP+L GD +TS +++++ + KGF Y A
Sbjct: 406 YIEVRDGYWRKSPLLGRFCGDKLPEV-LTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 43.9 bits (102), Expect = 0.003
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 2372 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2427
++YP C W + E+G + + + F+ E+E +D ++++DG + + L G
Sbjct: 909 NNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGS 968
Query: 2428 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
I S G V + + D NKKGF IRY
Sbjct: 969 -GPPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 213 bits (543), Expect = 2e-54
Identities = 179/657 (27%), Positives = 276/657 (42%), Gaps = 134/657 (20%)
Query: 436 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL--- 492
R + K CG LQ +G F++P FP Y S + CVW I+ K++ +NF DL
Sbjct: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIV-LNFTSMDLFKS 401
Query: 493 -EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
YD + + DG P +L G +P+ +VS S++W+ ++ ++ GF
Sbjct: 402 RLCWYDYVEVRDGYWRKAP--LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
Query: 552 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 611
Y + +CG G N+D
Sbjct: 460 Y----EATCG-------------GDMNKDA------------------------------ 472
Query: 612 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 667
G + SP+YP+ Y + C+W I G + L+F F++E
Sbjct: 473 --------------GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCA 518
Query: 668 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 727
+D+L V+DG + ES ++G F G E P + S+S+ L ++F +D S++ GF N F
Sbjct: 519 YDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF--AANFFKE 576
Query: 728 -NEC--PDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 784
+EC PD G CE + T G+ C D +
Sbjct: 577 VDECSWPDHG--------------------GCEHRCVNTLGSYKCAC---DPGYELAADK 613
Query: 785 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN--- 841
C CGG + +G I SPGWP Y + NC W + A + I + FE F+ E N
Sbjct: 614 KMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
Query: 842 -YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 900
YD +EV G + + L G + G++ P+ + S SN + + F +DN+ S GF+ H+
Sbjct: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF---- 729
Query: 901 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 960
+S D +G + + C +GY L HE C+ +
Sbjct: 730 ---FSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWL-HENGHDCK------------E 773
Query: 961 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDY 1016
A C + GT+ SP +P+ YP+ CTW + T G V+ F+ F +E H +D+
Sbjct: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
Query: 1017 LLITENGSFTQP-LARLTGSDLP-PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
L + + P L R GS P PT+ +G LRF SD S+ +GF S
Sbjct: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASG----SSMFLRFYSDASVQRKGFQAVHS 886
Score = 207 bits (526), Expect = 2e-52
Identities = 172/648 (26%), Positives = 281/648 (43%), Gaps = 126/648 (19%)
Query: 443 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 498
TCG ++ +G SPN+P Y + +CVW IT V+ + + F+ F++E YD
Sbjct: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 557
L + DG + ++ G P+ + S S+++W+ +D S+ GF N+ KE+++
Sbjct: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
Query: 558 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
S D G G +R V +G C + +A+ +C C
Sbjct: 580 CSWPDHG----------GCEHRCV---------NTLGSYKCACDPGYELAADKKMCEVAC 620
Query: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAV 673
T GT+ SP +P+ Y N NC+W +++ RI L F F+LE ++DF+ V
Sbjct: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
Query: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 733
+ G SP++ + G F G+E P +TS S+ +R+EF++D+++S RGF + + +EC
Sbjct: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDEC--- 736
Query: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
A+ G C+ + T G+ C +G + A C
Sbjct: 737 -----AKDNGG-----------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAH 778
Query: 794 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEVHD 849
S+ G + SP WP Y C W I + GH +K+TF F+ E + YD LE++D
Sbjct: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
Query: 850 GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDP 909
GP+ L+P+LG + G++ P +S + ++L F +D S GF+
Sbjct: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ---------------- 882
Query: 910 GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRG 969
VH S + G RL E + +SH GD
Sbjct: 883 --AVH----------------STECGGRLKAE----VQTKELYSHAQ-------FGDNNY 913
Query: 970 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF 1025
PS C W + G GV+ F TF +E+ +DY+ +
Sbjct: 914 PS--------------EARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDS 959
Query: 1026 TQP-LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
+ P L R GS L +AG +RF +D +I+ +GF+ ++
Sbjct: 960 SAPRLGRFCGSGPLEEIYSAG----DSLMIRFRTDDTINKKGFHARYT 1003
Score = 194 bits (494), Expect = 1e-48
Identities = 176/644 (27%), Positives = 261/644 (40%), Gaps = 124/644 (19%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CG L ++G +P FP+ YP C W I+V I L F S + + YD++
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1599
+ DG +PL+G F K+PE + S+ + + + FRS ++ GF Y+A +C
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TC-- 464
Query: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1659
G MN DAG + DD RP C
Sbjct: 465 -GGDMNK-----------------DAGQIQSPN------YPDDYRPS---------KECV 491
Query: 1660 SRSTGSEGTVLSPNYPKNYSVGH-NCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPT 1718
R T SEG + + H +C Y D +EV DGPT
Sbjct: 492 WRITVSEGFHVGLTFQAFEIERHDSCAY----------------------DYLEVRDGPT 529
Query: 1719 QQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVPRTSSTQCSS 1776
++S+L+ G E + SS N++ ++F S G I GF +F + +CS
Sbjct: 530 EESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEV------DECSW 582
Query: 1777 VPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1836
R N S C+PGY L + C V CG
Sbjct: 583 PDHGGCEHRCVNTL---GSYKCACDPGYELAADKKM------------------CEVACG 621
Query: 1837 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFY 1892
G +TK GTI SPG+P+ Y N NCVW++ P I +Q F E N +D ++
Sbjct: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
Query: 1893 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQ 1952
G +A G + G+ P ++ S SNN+ + F+SD +VS GF + + D C +
Sbjct: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAK-- 738
Query: 1953 TPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMS 2012
+ G + G + +C GY L + H C A C +S
Sbjct: 739 -DNGGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCKE--------------AGCAHKIS 781
Query: 2013 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSS 2068
G + SP +P YPS +CTW I+ G V L F F E +D+LE+ G
Sbjct: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
Query: 2069 ETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2112
+ ++GR G + P ++ L F+SD S ++GF V+
Sbjct: 842 SLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
Score = 187 bits (474), Expect = 2e-46
Identities = 144/469 (30%), Positives = 218/469 (46%), Gaps = 64/469 (13%)
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
A CGG M+ +G I SP +P +Y S +C W I + GF V L F F E +DY
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI-VYQAYQLQS 2119
LEVR G +E S +IG G + P + S+++ + F SD S NK GF ++ S
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
Query: 2120 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2179
PD + V T+G + C PGY L + + CE C
Sbjct: 582 WPDHGGCEHRCVN----TLG-SYKCACDPGYELAADKKM----------------CEVAC 620
Query: 2180 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITV 2235
GG IT +NGTI SPG+P EYP ++C W V P I + F V + E YDF+ V
Sbjct: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
Query: 2236 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2293
G ++ G+F G+ E + S SN + ++F SD T S GF
Sbjct: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF--------------- 725
Query: 2294 PPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2352
A ++ DE + +++C+ F G+ + CR G L +G C+
Sbjct: 726 -----RAHFFSDKDECAKDNGGCQHECVNTF---GSYLCRCRNGYWLHENGHD--CKEAG 775
Query: 2353 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2408
A+++ G + SP +PD YP+ + C W+IS G+ + + F+ E+ +D L
Sbjct: 776 CAHKIS-SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHL 834
Query: 2409 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2457
++YDGP+ +P+L G + S G +FL++ +D +KGF+
Sbjct: 835 EMYDGPDSLAPILGRFCGSKKPDPTVAS-GSSMFLRFYSDASVQRKGFQ 882
Score = 187 bits (474), Expect = 2e-46
Identities = 137/474 (28%), Positives = 213/474 (44%), Gaps = 73/474 (15%)
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
A CGG++ +G I SPN+P Y S++C W ITV+ + + L F +F IE + YD+
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
L + DGP S LIG F + PE ++SSSN + + F SDGS++ GF + ++ E
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
Query: 1598 F-DPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1653
+ D G G +++ +T+ Y CD GY L +
Sbjct: 582 WPDHG--------GCEHRCVNTLGSYKCACDPGYELAADKKM------------------ 615
Query: 1654 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV--- 1710
C CG T GT+ SP +PK Y NCV+ + P ++ + QF F+ +DV
Sbjct: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
Query: 1711 --VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAV 1766
VEV G + + L GS + E + S N + + F S ++ +GF HF
Sbjct: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVI-TSQSNNMRVEFKSDNTVSKRGFRAHFF---- 730
Query: 1767 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1826
+ +C+ N F S L C GY LH + C+
Sbjct: 731 --SDKDECAK-DNGGCQHECVNTF---GSYLCRCRNGYWLHEN-GHDCKE---------- 773
Query: 1827 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1885
C ++ +GT+ SP +P+ Y + C W I+ G +++ F E +
Sbjct: 774 ------AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQ 827
Query: 1886 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 1936
+D L+ YDG D+ AP LG + G+ P ++ ++++L F SD SV GF
Sbjct: 828 ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 184 bits (467), Expect = 1e-45
Identities = 137/465 (29%), Positives = 209/465 (44%), Gaps = 59/465 (12%)
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1189
A CG + G + SPNYP +Y + EC++ I V G + ++ + F + + D
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
L++ DG + + L+G F G + + S+SN+LW++F SD GF + E+
Sbjct: 522 LEVRDGPTEESALIGHFCGYE-KPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
Query: 1250 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
C P ++ ++ G + + C+PGY L + C
Sbjct: 580 CSWPDHGGCEHRCVNTLGSYKCA-----CDPGYELAADKKM----------------CEV 618
Query: 1309 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1364
CGG F + +G I SPG+P Y N C+W + +SLQF F+ E + +D
Sbjct: 619 ACGG-FITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 1365 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
+ V G + L GS PE I S N + ++F +D +SK GF F S
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
Query: 1425 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
+D G + N G + + +C GY L E C + A C
Sbjct: 738 KDNGGCQHECVNTFG-----SYLCRCRNGYWLH-ENGHDCKE---------------AGC 776
Query: 1485 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1540
++ G + SPN+P YP R+C W I+ A + + L F F IE + YD L +
Sbjct: 777 AHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEM 836
Query: 1541 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1585
YDGPDS +P++G F SK P+ +S ++M L F SD SV GF
Sbjct: 837 YDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 176 bits (446), Expect = 4e-43
Identities = 138/482 (28%), Positives = 212/482 (43%), Gaps = 60/482 (12%)
Query: 778 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 837
++ G A CGG + +G I SP +P Y+ S C W I G + +TF+ F+
Sbjct: 451 ILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFE 510
Query: 838 TELN----YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFK 893
E + YD LEV DGP S L+G + G + P+ + SSSN +++ F +D S + GF
Sbjct: 511 IERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF- 569
Query: 894 IHYESVTVNTYSCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 952
N + +D P HG + + +CD GY L+ ++ +
Sbjct: 570 ------AANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-------- 615
Query: 953 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1012
C+ CGG + +GTI SPG+P+ YP + NC W V + F F LE
Sbjct: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
Query: 1013 H----HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFN 1067
+ +D++ + S L R GS+ P I + N R + F SD ++S GF
Sbjct: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-QSNNMRVE--FKSDNTVSKRGFR 726
Query: 1068 ITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1127
F E +D G Q+ F + C +GY L C G
Sbjct: 727 AHFFSDKDECAKDNGGCQHECVNTFG-----SYLCRCRNGYWLHENGH-DCKEAG----- 775
Query: 1128 APLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1187
C ++ EG L SPN+P Y + EC ++I AG + ++ F + Q
Sbjct: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
Query: 1188 -----DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
D L++YDG D +LG F G+ T++S S+ ++L F SD +GFQ V+
Sbjct: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
Query: 1243 TS 1244
++
Sbjct: 886 ST 887
Score = 163 bits (413), Expect = 2e-39
Identities = 163/684 (23%), Positives = 259/684 (37%), Gaps = 165/684 (24%)
Query: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 119
TCGG + G I+SP +P Y C W I E + + FQ+F +E YDYL
Sbjct: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
Query: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSC 178
+ DG + G+ P V S+ + ++ SD +++ GF +++E+ S
Sbjct: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
Query: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
P G + + +C GY L ++ E
Sbjct: 583 -----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------------CE 617
Query: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 294
ACGG + +G I+SP +P EY N +C W +VA ISL F F++E KYD+
Sbjct: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 295 LEIEGSEPPTIWLSGM----NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
+E+ P L G P I S N +R+ F +D+
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNT-----------------V 720
Query: 351 KSRGFK--LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSC 408
RGF+ F KD K + GG Q C
Sbjct: 721 SKRGFRAHFFSDKDECAK----DNGGC-----------------------------QHEC 747
Query: 409 DEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNA 468
+ G+ C+ + D CK C + GT SPN+P +Y S
Sbjct: 748 VNTF---GSYLCRCRNGYWLHENGHD----CKEAGCAHKISSVEGTLASPNWPDKYPSRR 800
Query: 469 QCVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPD 524
+C W I++ ++V ++ F EF++E YD L + DG + P +L GS PD
Sbjct: 801 ECTWNISSTAGHRV-KLTFNEFEIEQHQECAYDHLEMYDGPDSLAP--ILGRFCGSKKPD 857
Query: 525 LIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF 584
V+ S M+L +D SV GF+ + CG G ++ + +S+
Sbjct: 858 PTVASGSSMFLRFYSDASVQRKGFQA----VHSTECG--GRLKAEVQTKELYSH------ 905
Query: 585 ECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCI 644
QFG +NN Y + C
Sbjct: 906 -AQFG------------DNN--------------------------------YPSEARCD 920
Query: 645 WTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNS 700
W I+++ G + L+F F++E + +D++ DG +P LG F G+ + S
Sbjct: 921 WVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAG 980
Query: 701 HILRLEFQADHSMSGRGFNITYNT 724
L + F+ D +++ +GF+ Y +
Sbjct: 981 DSLMIRFRTDDTINKKGFHARYTS 1004
Score = 155 bits (391), Expect = 9e-37
Identities = 133/508 (26%), Positives = 218/508 (42%), Gaps = 102/508 (20%)
Query: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YD 293
E CGG M +G I SP++P++Y + +C W I G + L F F++E YD
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 294 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
YLE+ L G P + S+ N L + FV+D + GF+A + K +D
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFF--KEVD 578
Query: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
+ S + GG + + C + +LGS + +CD
Sbjct: 579 ----------------ECSWPDHGGCE---HRCVN--------------TLGS-YKCACD 604
Query: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Y L K + C+V CG + +GT TSP +P +Y +N
Sbjct: 605 PGYELAADKKM------------------CEV-ACGGFITKLNGTITSPGWPKEYPTNKN 645
Query: 470 CVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDL 525
CVW + A + I + FE F+LE YD + + G + + GS P++
Sbjct: 646 CVWQVVAPAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGSETPEV 702
Query: 526 IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF- 584
I S S+ M + ++D +V GF+ ++ +K+ C ++ G + V F
Sbjct: 703 ITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECA---------KDNGGCQHECVNTFG 752
Query: 585 ----ECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNN 640
C+ G+ L E C+E C ++ GT+ SP++P+ Y +
Sbjct: 753 SYLCRCRNGYWL-HENGHDCKEAG------------CAHKISSVEGTLASPNWPDKYPSR 799
Query: 641 LNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHL 696
C W I S G R+ L+FN+F++E +D L + DG +PILG F G++ P
Sbjct: 800 RECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPT 859
Query: 697 TSNSHILRLEFQADHSMSGRGFNITYNT 724
++ + L F +D S+ +GF ++T
Sbjct: 860 VASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 143 bits (360), Expect = 3e-33
Identities = 160/648 (24%), Positives = 249/648 (38%), Gaps = 124/648 (19%)
Query: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
+A CGGD+ +G I SP YP+ Y S C W + V+ G V F F +E H +D
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
YL + + + L G + P + + + R ++F+SD SI+ GF F +
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKS---SSNRLWMKFVSDGSINKAGFAANFFK-E 576
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
++ C P R G + +C GY L +A C
Sbjct: 577 VDECSWPDHGGCEHRCVNTLG---SYKCACDPGYEL----------------AADKKMCE 617
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
CG T G + SP +P Y N C++ + A I++ F L DV K
Sbjct: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
+ G L G F G+ + ++S SN + +EF SD + GF+ + S +
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
Query: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGC-NPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
+D G GC + GS L +C G W +
Sbjct: 737 AKDNG---------------------GCQHECVNTFGSYLCRCRNG---YWLHENGHDCK 772
Query: 1309 ECGGRFKGES-SGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHD 1363
E G K S G + SP +P Y + C W I G+ V L F F+ E ++D
Sbjct: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
Query: 1364 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1423
L ++DGP +L GS P+ ++ + + ++F +D + + GF S T
Sbjct: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS----TE 888
Query: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQV-ENRYFWQPSPPVCIA 1482
C GR E+Q +E + Q +N Y PS A
Sbjct: 889 C-------------GGRLKA-----------EVQTKELYSHAQFGDNNY---PSE----A 917
Query: 1483 PCGGNLTGSSGFILSPNF-PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
C + G+ + F DC + DY+ + YD
Sbjct: 918 RCDWVIVAEDGYGVELTFRTFEVEEEADCGY------DYMEA-----------YD----- 955
Query: 1542 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1589
G DS++P +G F S E I S+ +++ + FR+D +++ GFH Y
Sbjct: 956 -GYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 108 bits (270), Expect = 9e-23
Identities = 83/299 (27%), Positives = 134/299 (44%), Gaps = 40/299 (13%)
Query: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
EA CGG++ G I SP YPD+Y ++C W + V G + + F + E YD
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2289
++ V DGP + S IG F G E V S+SN++ +KF SD +GF
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF----------- 569
Query: 2290 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2347
A E DE D ++C+ +G+ C G L D +
Sbjct: 570 ---------AANFFKEVDECSWPDHGGCEHRCV---NTLGSYKCACDPGYELAAD--KKM 615
Query: 2348 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2403
C+V C +L+ G I SPG+P YP + C W + Y I++ E F+ E
Sbjct: 616 CEVACGGFITKLN--GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
Query: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
++D ++V G + + + G + ITS + + +++ +D+ +K+GFR + +
Sbjct: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
Score = 70.1 bits (170), Expect = 4e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
L +C A CG + G +PG+P+ YP++ C W + V PG I +NFT +
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFF 2279
YD++ V DG + +P +G+F G+ E + ST +++ ++F S+ GFF
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
Score = 67.8 bits (164), Expect = 2e-10
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
CG + D +G +PGFP YPS C W I++ G + L F + S +DY+E
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
VR G + ++GR G +IP L ST + F S + +GF Y+A
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
Score = 66.2 bits (160), Expect = 5e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
ACG T++ ++G S+P FPN Y + + C W I PG+ I L FT + + YDY+
Sbjct: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
Query: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
E+ P G IP P++S + L + F + SN +GF A Y+
Sbjct: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
Score = 64.7 bits (156), Expect = 2e-09
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CG TL+ G +PGFP GYP+ ++C W I +I + F S L + YDY+
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
+ DG+ R G +P P+ ST S + S + GF YE ++CG
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG 465
Score = 63.2 bits (152), Expect = 5e-09
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
L G + + + KC A CG +G +PG+P Y +C W I PG I +
Sbjct: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
Query: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
F + F++ L YD +EV DG +PLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
Query: 889 NNGFKIHYES 898
GF YE+
Sbjct: 453 GKGFFAAYEA 462
Score = 63.2 bits (152), Expect = 5e-09
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 32/208 (15%)
Query: 712 SMSGRGFNITYNTFG---HNEC----------PDPGIPINARRFGDNFQLGSSISVICEE 758
S +G +T+N F H EC PD PI R G + S
Sbjct: 808 STAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVAS----- 862
Query: 759 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAP--SGVILSPGWPG--YYKDS 814
G+ D V G CGG A + + S G Y
Sbjct: 863 ------GSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSE 916
Query: 815 LNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFL 870
C+WVI AE G+ +++TF F+ E YD +E +DG + +P LG + G+ + +
Sbjct: 917 ARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEI 976
Query: 871 FSSSNFIYLLFTTDNSRSNNGFKIHYES 898
+S+ + + + F TD++ + GF Y S
Sbjct: 977 YSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 62.0 bits (149), Expect = 1e-08
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 2179 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2230
CGG + A T +YS + YP+ C W++ G G+ + F + E Y
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT 2274
D++ +DG D ++P++G+F G+ LE +YS + ++I+F +D T
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNL----NCVWKITVPEGAGIQVQVVSFATEHN----W 1886
CGG L T + + DNN C W I +G G+++ +F E +
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 1942
D ++ YDG D++APRLG + G+ + S ++L + F++D +++ GFH YT+
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 56.6 bits (135), Expect = 4e-07
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 2026 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2081
NYPS C W I G+GV L F F E +DY+E G ++ +GR G
Sbjct: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
Query: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
++S + F +D + NK+GFH Y + + Q
Sbjct: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
Score = 54.7 bits (130), Expect = 2e-06
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 1309 ECGGRFKGESSGRILSPGYPFP---YDNNLRCMWMIEVDPGNIVSLQFLAFDTE----AS 1361
ECGGR K E + L F Y + RC W+I + G V L F F+ E
Sbjct: 888 ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCG 947
Query: 1362 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1419
+D + +DG + L GS E I+S + + I+F TD I+K GF +++S+
Sbjct: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005
Score = 51.6 bits (122), Expect = 1e-05
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
R L C A CG + G +P +P Y +CV+ I+V P E +V F F++
Sbjct: 343 RKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKS 401
Query: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
L +D VEV DG +++ LL G E L +S+ +++ + F S I KGF Y
Sbjct: 402 RLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAY 460
Query: 1764 QA 1765
+A
Sbjct: 461 EA 462
Score = 51.2 bits (121), Expect = 2e-05
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1187
L +C A CG + + G +P +P Y + C++ I V G+ I ++ + L +
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 1188 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
D +++ DG + LLG F G + L ST ++LW+EF S + +GF Y
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPE-PLVSTDSRLWVEFRSSSNILGKGFFAAY 460
Score = 51.2 bits (121), Expect = 2e-05
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 2372 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2427
++YP+ C W I E GY + + F+ E+E +D ++ YDG + +P L G
Sbjct: 911 NNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS 970
Query: 2428 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
I S G + +++ D NKKGF RY
Sbjct: 971 -GPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 50.1 bits (118), Expect = 4e-05
Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 12/121 (9%)
Query: 241 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 292
CGG ++ + + S F N Y + A C W IVAE G + L F F++EE+ Y
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 293 DYLE----IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
DY+E + S P G I S + L + F TD +GF A Y K
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
Query: 349 D 349
D
Sbjct: 1009 D 1009
Score = 47.8 bits (112), Expect = 2e-04
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
CPA E D+TG +PG+P+ YP+ C W ISV G I + K +D
Sbjct: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
++V DG ++P+L GD + S +++++ + KGF Y A
Sbjct: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
Score = 44.3 bits (103), Expect = 0.002
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 1156 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1210
NY + C + I + G G+ ++ RTF + + D ++ YDG D + LG F G+
Sbjct: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
Query: 1211 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
+ S + L + F +D +GF YTS
Sbjct: 972 PLE-EIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 34.7 bits (78), Expect = 1.7
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 1708 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
+D +E YDG + L GS E + S+G+ + IRF + I KGFH Y
Sbjct: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEI-YSAGDSLMIRFRTDDTINKKGFHARY 1002
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 [Homo
sapiens]
Length = 840
Score = 212 bits (540), Expect = 5e-54
Identities = 194/740 (26%), Positives = 292/740 (39%), Gaps = 79/740 (10%)
Query: 1830 TCIVPCGGILTKRKGTILSPGYPEPYDNNL---NCVWKITVPEGAGIQVQVVSFATEHNW 1886
T V C +++ +G + SP P L +C + I V G GI++QV +
Sbjct: 98 TSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEE 157
Query: 1887 DSLDFYDGGDNN-APRLGSYSGTTIP-HLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIG 1944
+ L GG APRL + S +L S +N L L+FQS GF + Y A
Sbjct: 158 ELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYL 217
Query: 1945 LDSCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
L SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C
Sbjct: 218 L-SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 2004 LAQCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE 2062
+A CGG + + + G I+SP G +L C W I G +HL F S + +D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 2063 VRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2121
VRSG S S VI +P L S + S+ N + ++A++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 2122 DPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCE 2176
P +G V D + G +F C PGY L +A+ C+ +WN P C+
Sbjct: 396 APF-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 454
Query: 2177 ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2236
A+CGG ++ G + SP +P Y QDC W V V I + +L D +T++
Sbjct: 455 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLF 513
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRV 2290
DG ++ + Q G + S+ + ++F + GF + +
Sbjct: 514 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 573
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
C PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ- 630
Query: 2351 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2410
+ CA + G+ ++ F V
Sbjct: 631 -------------------------KIMTCADPGEIANGHRTA-------SDAGFPV--- 655
Query: 2411 YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CST 2467
G ++Q Y + G + +S D G K R+ A C
Sbjct: 656 --GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLN 703
Query: 2468 PESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2526
P P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 704 PGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCKVT 761
Query: 2527 SCGIPKAPTNGGILTTDYLV 2546
P GG L L+
Sbjct: 762 QTTDPSRQLEGGNLALAILL 781
Score = 207 bits (528), Expect = 1e-52
Identities = 186/714 (26%), Positives = 298/714 (41%), Gaps = 82/714 (11%)
Query: 791 CGGHFSAPSGVILSPGWPGYYKDSL---NCEWVIEAEPGHSIKITFERFQTELNYDVLEV 847
C + S G + SP +L +C + I PG+ I+I + ++L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 848 HDG--PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYS 905
G P L LL + + Q L S +N + L F + GF+IHY++ + S
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL---S 219
Query: 906 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDALC 963
C P P HG D G T +F CDSGY+L EE L+C W+ P+C A C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 279
Query: 964 GGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1022
GG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 1023 GSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCEDP 1081
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C P
Sbjct: 340 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 397
Query: 1082 GIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAEC 1137
+ + + G TFSC GY LE + I C+ W+ P C A C
Sbjct: 398 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 457
Query: 1138 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1197
G + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 458 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 517
Query: 1198 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CED 1252
+ +L G R LSS L L+F + G +GF L + + C +
Sbjct: 518 PSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 576
Query: 1253 PGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAE 1309
P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 577 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMT 634
Query: 1310 CGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVW 1368
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT---- 682
Query: 1369 DGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPG 1428
P +D + K A+++ C +PG
Sbjct: 683 GTPKWSDRVPK--------------------------------CALKYE-----PCLNPG 705
Query: 1429 VPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
VP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 706 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 758
Score = 206 bits (524), Expect = 3e-52
Identities = 190/781 (24%), Positives = 318/781 (40%), Gaps = 96/781 (12%)
Query: 1317 ESSGRILSPGYPFPYDNNLR---CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1373
E G + SP P L C + I V PG + +Q + ++L + G
Sbjct: 109 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 168
Query: 1374 NDMLLKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
+ S++ EG + S N + + F + GF I + + + + C P P
Sbjct: 169 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPA 227
Query: 1432 NGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGS 1491
+G + PG T F CD GY+LQGEE + C+ R W P C+A CGG + +
Sbjct: 228 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 286
Query: 1492 S-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPL 1550
+ G I+SP + C W I + L F S++ + D L + G SP+
Sbjct: 287 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 346
Query: 1551 IGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP----GNIMN 1605
I +PER + S + ++++ S+ + L ++A + CF P GN+
Sbjct: 347 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV-- 404
Query: 1606 GTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGWNRALPSCHAPCGSRS 1662
T +Y+ G+ T+ C GY L+ + + C+ D P WN P+C A CG
Sbjct: 405 -TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACKAMCGGEL 461
Query: 1663 TGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS 1722
+ G VLSP++P++YS G +CV+ + V +E + Q D++ ++DG +
Sbjct: 462 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSAR 521
Query: 1723 LLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVYQAVPRTSSTQCSSVP 1778
+L+ L G L LSSG +T++F + P +GF ++ VPR + C +P
Sbjct: 522 VLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELP 578
Query: 1779 EPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1836
P +G R + + G+ + + C PGY L GS + C QW+ S C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--------QWDLSWSAAPPACQ 630
Query: 1837 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSLDFYDGG 1895
I+T ++ G+ D P G+ +Q + + ++ E
Sbjct: 631 KIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGYSLE------------ 670
Query: 1896 DNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPS 1955
A L YS D + A+ + C P P
Sbjct: 671 --GAAMLTCYS--------------------RDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 1956 SGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMS 2012
+G + Y G+ + F C +G+ L G ITC+PG +W P+C + Q
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSR 768
Query: 2013 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETST 2072
G GN ++ + + +G GV++ + +++ + SGS S
Sbjct: 769 QLEG--------GNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGF----SGSHSYSP 816
Query: 2073 V 2073
+
Sbjct: 817 I 817
Score = 204 bits (519), Expect = 1e-51
Identities = 180/667 (26%), Positives = 280/667 (41%), Gaps = 41/667 (6%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSL---DCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
C +S+ G + SP +L DCT++I++ G+G+ +Q + + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2064 RSGSSE--TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2121
G S ++ S L S T+ L+F S GF I YQAY L
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGF 222
Query: 2122 DPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGG 2181
PRP +G V D G T +F C GY L G L CL+G +WN P C A CGG
Sbjct: 223 PPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGG 281
Query: 2182 NI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPD 2240
I A G I SP C W++ G ++++F + + D + V G
Sbjct: 282 TIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGS 341
Query: 2241 QNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRVCQPPPPVP 2298
SP I + E + S + + ++ S+ + + L + A++ C P +
Sbjct: 342 PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF-LA 400
Query: 2299 NAEILTEDDEFEIGDIIRYQCLPGFTLVG----NAILTCRLGERLQMDGAPPVCQVLCPA 2354
+ + T D E+ G + + CLPG+ L NAI C + P C+ +C
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEPACKAMC-G 458
Query: 2355 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2414
EL + GV+LSP +P SY Q C W + V++ I + VE +E D+L ++DG
Sbjct: 459 GELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGDMLTLFDGD 516
Query: 2415 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPES---- 2470
+ VL L G + S+G ++ LQ+ A G G ++ + P +
Sbjct: 517 GPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 575
Query: 2471 ---PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2525
PP + + G L +V+ + C+ G+ L+G C+ +W A PACQ
Sbjct: 576 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWSAAPPACQK 631
Query: 2526 I-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2582
I +C P NG +D + VG+ V Y C GY L + T + GT ++
Sbjct: 632 IMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV 691
Query: 2583 PRCVV--ISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSS--GLW 2636
P+C + C P NG + + Y G + F C GF L+G C+ W
Sbjct: 692 PKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 751
Query: 2637 SESETRC 2643
+ C
Sbjct: 752 TSQPPLC 758
Score = 182 bits (463), Expect = 4e-45
Identities = 155/571 (27%), Positives = 239/571 (41%), Gaps = 31/571 (5%)
Query: 1137 CGASATNNEGILLSPNYPLNYENNH---ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1193
C + + EG + SP+ +C YSI V G GI I +T +L+Q + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1194 DGKDKTTHLLGAFTGASM--RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1251
G +SM G L S +N+L L F S GF++ Y ++ LS C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 1252 DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECG 1311
P P G +S G T + C+ GY L G L C+ G R +W+ PSC+A CG
Sbjct: 222 FPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1312 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1371
G + GRI+SP NL C W+IE G + L F + +D L V G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1372 PENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1430
++ + +PE G+ S + ++ ++ + +++F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1431 M-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCIAPCGG 1486
N T PG F C PGY L+ I C+ + W + P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKAMCGG 459
Query: 1487 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1546
L+ +G +LSP++P Y +DC W + V + I L ++ D L ++DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1547 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ESC--FD 1599
++ ++ + + R+ SS + L F++ GF L +K R ++C
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH---- 1655
P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMT 634
Query: 1656 -APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1685
A G + G T +P V + C+
Sbjct: 635 CADPGEIANGHR-TASDAGFPVGSHVQYRCL 664
Score = 171 bits (432), Expect = 2e-41
Identities = 193/787 (24%), Positives = 301/787 (38%), Gaps = 119/787 (15%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSR---DCDWTITVNADYVISLAFISFSIEPNYDFLYI 1540
C N++ G++ SP+ P + DC ++I V Y I + + ++ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1541 YDGPD--------SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1592
G +NS ++G Q + P +N + L F+S GF + Y+A
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSP------TNRLLLHFQSPRVPRGGGFRIHYQAY 216
Query: 1593 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
L SC P +G D G T T++CD+GY LQG TL C+ G RP WN P
Sbjct: 217 LL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 273
Query: 1653 SCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---H 1708
SC A CG + G ++SP +VG N + F + SL +
Sbjct: 274 SCMASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 331
Query: 1709 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
D + V G + S ++ E +S + + S P ++A
Sbjct: 332 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF-- 389
Query: 1769 TSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQ 1823
+C + P G E+ G+ F C PGY L AI C V +
Sbjct: 390 -EEDRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPH 445
Query: 1824 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1883
WND+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 446 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNV 504
Query: 1884 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLE 1939
D L +DG +A L G L S+ +L L FQ+ GF L
Sbjct: 505 REGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH 564
Query: 1940 YTAIGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 1996
+ + D+CPE P G + + G V+++QC+ GY L G +TC W
Sbjct: 565 FKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSW 622
Query: 1997 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2056
+ P C I++ PG + P+G H+Q+ +
Sbjct: 623 SAAPPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYS 668
Query: 2057 IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2116
+ + S +T T K + A +
Sbjct: 669 LEGAAMLTCYSRDTGTP-------------------------------KWSDRVPKCALK 697
Query: 2117 LQSCPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
+ C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 2175 CEA---------LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQ 2225
C+ L GGN+ I P LV + G+G+YI +T LQ
Sbjct: 758 CKVTQTTDPSRQLEGGNLAL---AILLP------------LGLV-IVLGSGVYIYYTKLQ 801
Query: 2226 TEPIYDF 2232
+ ++ F
Sbjct: 802 GKSLFGF 808
Score = 167 bits (422), Expect = 2e-40
Identities = 138/556 (24%), Positives = 231/556 (41%), Gaps = 23/556 (4%)
Query: 444 CGSNLQGPSGTFTSPNFPFQYDSNA---QCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
C +N+ G SP+ C + I V I+I + +L + L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIH-VYPGYGIEIQVQTLNLSQEEELLV 161
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
+ GG G +L + ++ S ++++ LH Q+ GF+++Y+ SC
Sbjct: 162 LAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SC 220
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 618
G P P +G F C G++L GE++++C + W+ P C+ C
Sbjct: 221 GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 619 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 677
A +G ++SP+ G NL C W I + G R+HL F L+ D L V+ G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 678 SPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 736
SP SP++ +VP L S++ L +E ++ + ++ + F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 737 I-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH 794
N ++ G+ + C G+ ++ G + + W+ P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE 460
Query: 795 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 854
S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 461 LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPS 519
Query: 855 SPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLDPG 910
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 520 ARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPELP 578
Query: 911 IPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG-- 964
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Query: 965 GDVRGPSGTILSPGYP 980
G++ T G+P
Sbjct: 639 GEIANGHRTASDAGFP 654
Score = 131 bits (330), Expect = 1e-29
Identities = 154/572 (26%), Positives = 231/572 (40%), Gaps = 68/572 (11%)
Query: 65 CGGTLKGLNGTIESP--GFPYGYPNGA-NCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
C + G +ESP G P G +CT+ I I+I Q+ L +E + L L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 122 YDGHPHPTNFRTRLTGFHLPPP--VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
G R L + S + L S GF+++Y+ S CG
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
P P G + T G + C +GY L G L C+ + SW+ P C A
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCMA-- 277
Query: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 297
+CGGT+ ++ G I SP N C W I A G + L F ++E D L +
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 298 EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSR 353
G P P I+ S M+ P +IS+ L + ++++ S ++ + + R
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE----EDR 393
Query: 354 GFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV 413
F F L G + T DP ++ G+ FSC Y
Sbjct: 394 CFAPF-----------LAHGNVTTT-----DP-----------EYRPGALATFSCLPGYA 426
Query: 414 LQ---GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQC 470
L+ +I C E W+D P CK CG L P+G SP++P Y C
Sbjct: 427 LEPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDC 483
Query: 471 VWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMS 530
VW + V K I + E ++ G D LT+ DG G VL L G ++S
Sbjct: 484 VWGV-HVQEEKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLLSSG 539
Query: 531 SQMWLHLQT-----DESVGSVGFKVNYKEIEK-ESCGDPGTPLYGIR---EGDGFSNRDV 581
+ L Q + +G GF +++KE+ + ++C + P +G R GD V
Sbjct: 540 PDLTLQFQAPPGPPNPGLGQ-GFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTV 597
Query: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
L ++C+ G+EL+G + CQ + WSA P C
Sbjct: 598 LTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Score = 128 bits (321), Expect = 1e-28
Identities = 132/581 (22%), Positives = 224/581 (38%), Gaps = 88/581 (15%)
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNA---DCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
C + G + SP + DCT++I PG I + + ++ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 298 EGSEPPTIWLSGMNIPPPIISNK-------------NWLRLHFVTDSNHRYRGFSAPYQV 344
G P + P +++N N L LHF + R GF YQ
Sbjct: 163 AGGGSP-------GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 215
Query: 345 KKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTV 404
+L+ C P P +G +D G T
Sbjct: 216 Y-----------------------LLS----------CGFPPRPAHGDVSVTDLHPGGTA 242
Query: 405 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GTFTSPNFPFQ 463
F CD Y LQG +++ C + +W+ P C + +CG + + G SP
Sbjct: 243 TFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-MASCGGTIHNATLGRIVSPEPGGA 299
Query: 464 YDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP 523
N C WVI A + + ++FE L+ D L + GG P V+ S +
Sbjct: 300 VGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGSPLSP-----VIYDSDMD 353
Query: 524 DL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGD-GFSN 578
D+ ++S + +++ L ++ + + ++ E++ C P + D +
Sbjct: 354 DVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRP 413
Query: 579 RDVLRFECQFGFELI---GEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDY 633
+ F C G+ L +I C + + W+ P C C + P G VLSPD+
Sbjct: 414 GALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDW 473
Query: 634 PEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVP 693
P+ Y +C+W + RI L ++ + D L + DGD P + +L G +
Sbjct: 474 PQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPR 532
Query: 694 SHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFGHNE-CPDPGIPINARRFGDNFQL 748
L S+ L L+FQA + G+GF + + N+ CP+ P R + L
Sbjct: 533 RRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDL 592
Query: 749 --GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
G+ ++ CE G+ + G++ +TC + WS P C
Sbjct: 593 IRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPAC 629
Score = 92.0 bits (227), Expect = 9e-18
Identities = 106/445 (23%), Positives = 163/445 (36%), Gaps = 75/445 (16%)
Query: 54 TVSCVKGFIYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFAL 112
T SC+ +CGGT+ G I SP C WVI A E R+ + F+ +L
Sbjct: 272 TPSCMA----SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSL 327
Query: 113 EEEYDYLSLYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 170
+E+ D L + G P + + + ++ +S++ + L S+ + + +
Sbjct: 328 DEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRF 386
Query: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTA 226
E + C P + V + G +SC+ GY L+ G P + C+
Sbjct: 387 EAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEP 444
Query: 227 SWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF 286
W+ P C+A CGG + +G++ SP +P Y DC W + + I L
Sbjct: 445 HWNDTEPACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEIL 502
Query: 287 QMEEKYDYLEIEGSEPPTIWLSGMNIPPP---IISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
+ E +G P L+ + P P ++S+ L L F G +
Sbjct: 503 NVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFV 562
Query: 344 VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASN----------------------- 380
+ FK P D + E G +TAS+
Sbjct: 563 LH---------FKEVPRNDTCPELP-PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 612
Query: 381 ---------------------LCPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGA 417
C DPGE NG R SD F +GS VQ+ C Y L+GA
Sbjct: 613 ILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGA 672
Query: 418 KSITCQRIAEVFAAWSDHRPVCKVK 442
+TC WSD P C +K
Sbjct: 673 AMLTCYSRDTGTPKWSDRVPKCALK 697
Score = 89.0 bits (219), Expect = 8e-17
Identities = 62/203 (30%), Positives = 85/203 (41%), Gaps = 12/203 (5%)
Query: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 571 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 630
Query: 2823 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 2875
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 631 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 690
Query: 2876 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 2931
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 691 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 749
Query: 2932 SWTGRQPECKAVQCGNPGTTANG 2954
WT + P CK Q +P G
Sbjct: 750 QWTSQPPLCKVTQTTDPSRQLEG 772
Score = 85.9 bits (211), Expect = 7e-16
Identities = 63/195 (32%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 2950 TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIISCGDPG 3008
T ++G + R GT + Y C GY L G + C + +WS P C I++C DPG
Sbjct: 586 TASHGDLIR--GTVLT----YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG 639
Query: 3009 IPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGT----WSGVMPTC--R 3060
ANG R D + VG +V Y C PGY++E G+ + TC T WS +P C +
Sbjct: 640 EIANGHRTASDAGFPVGSHVQYRCLPGYSLE--GAAMLTCYSRDTGTPKWSDRVPKCALK 697
Query: 3061 AVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTWSGEVPQ 3116
C P NG L ++ G S+ + C G+EL +TCV W+ + P
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 3117 CLPKFCGDPGIPAQG 3131
C DP +G
Sbjct: 758 CKVTQTTDPSRQLEG 772
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3063 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3119
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 3120 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3173
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 3174 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3230
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 693 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 751
Query: 3231 SGIQPEC 3237
+ P C
Sbjct: 752 TSQPPLC 758
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2667 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2722
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 594 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 653
Query: 2723 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2776
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 654 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 713
Query: 2777 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2821
H + G + + C G+ L G + C P QW P C
Sbjct: 714 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 73.6 bits (179), Expect = 3e-12
Identities = 63/245 (25%), Positives = 97/245 (39%), Gaps = 37/245 (15%)
Query: 2589 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA- 2645
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 2646 GHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHN----WSGQLP 2699
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 2700 SCVPV--SCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2753
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 2754 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--------------GTVVFYDCNPGYF 2799
PP+CKV +DP ++E GN G ++Y G
Sbjct: 753 SQPPLCKVTQTTDP--------SRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKS 804
Query: 2800 LFGSS 2804
LFG S
Sbjct: 805 LFGFS 809
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/136 (32%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 2827 GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 2886
G PG+ P + + G + S T + L QS R + G Q + +
Sbjct: 166 GSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 219
Query: 2887 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKAV 2943
CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA- 277
Query: 2944 QCGNPGTTANGKVFRI 2959
CG GT N + RI
Sbjct: 278 SCG--GTIHNATLGRI 291
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3178 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3236
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 569 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 628
Query: 3237 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3289
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 684
Query: 3290 --WTGKVPIC 3297
W+ +VP C
Sbjct: 685 PKWSDRVPKC 694
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 173 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 753
Query: 231 PVPICR 236
P+C+
Sbjct: 754 QPPLCK 759
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
Query: 3062 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3118
++C PP+ ++G + T+ G + ++ C GY+L L C+ NGT W+GE P C+
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCM 276
Query: 3119 PKFCG 3123
CG
Sbjct: 277 AS-CG 280
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 555 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 610
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 755
Query: 611 PIC 613
P+C
Sbjct: 756 PLC 758
Score = 40.8 bits (94), Expect = 0.024
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2587 VISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2644
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2645 AGHCGIPELIVNGQVIGENYG 2665
A G G+++ G
Sbjct: 277 ASCGGTIHNATLGRIVSPEPG 297
Score = 40.4 bits (93), Expect = 0.031
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3182 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3238
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 219 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 40.4 bits (93), Expect = 0.031
Identities = 39/148 (26%), Positives = 55/148 (37%), Gaps = 27/148 (18%)
Query: 1595 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 699 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 756
Query: 1653 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1712
C V P G N +I +P V+ L V
Sbjct: 757 LC-------------KVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 794
Query: 1713 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1740
+Y Q SL SGSHS + + S
Sbjct: 795 IYYTKLQGKSLF-GFSGSHSYSPITVES 821
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3001 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3057
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 273
Query: 3058 TCRAVTCPTPPQISNGRL 3075
+C A T + GR+
Sbjct: 274 SCMASCGGTIHNATLGRI 291
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2648 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD--HNWSGQLPSCVPVS 2705
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 278
Query: 2706 CG 2707
CG
Sbjct: 279 CG 280
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 382 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 701 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 758
Query: 440 KV 441
KV
Sbjct: 759 KV 760
Score = 35.8 bits (81), Expect = 0.77
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2704 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2759
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 35.0 bits (79), Expect = 1.3
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 2820 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 2876
+ ++ CG P P + +S G T + C L G+ + C LNG W+G
Sbjct: 214 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGET 272
Query: 2877 PHCSGDATGT 2886
P C GT
Sbjct: 273 PSCMASCGGT 282
Score = 34.3 bits (77), Expect = 2.2
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3241 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3298
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 276
Query: 3299 A 3299
A
Sbjct: 277 A 277
Score = 32.7 bits (73), Expect = 6.5
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 3444 MSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVHEN 3501
+++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 760 VTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSP 816
Query: 3502 NNGQAAFENPMYD 3514
++ F NP+Y+
Sbjct: 817 ITVESDFSNPLYE 829
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 [Homo
sapiens]
Length = 910
Score = 212 bits (540), Expect = 5e-54
Identities = 194/740 (26%), Positives = 292/740 (39%), Gaps = 79/740 (10%)
Query: 1830 TCIVPCGGILTKRKGTILSPGYPEPYDNNL---NCVWKITVPEGAGIQVQVVSFATEHNW 1886
T V C +++ +G + SP P L +C + I V G GI++QV +
Sbjct: 168 TSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEE 227
Query: 1887 DSLDFYDGGDNN-APRLGSYSGTTIP-HLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIG 1944
+ L GG APRL + S +L S +N L L+FQS GF + Y A
Sbjct: 228 ELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYL 287
Query: 1945 LDSCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
L SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C
Sbjct: 288 L-SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Query: 2004 LAQCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE 2062
+A CGG + + + G I+SP G +L C W I G +HL F S + +D L
Sbjct: 346 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 405
Query: 2063 VRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2121
VRSG S S VI +P L S + S+ N + ++A++ C
Sbjct: 406 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 465
Query: 2122 DPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCE 2176
P +G V D + G +F C PGY L +A+ C+ +WN P C+
Sbjct: 466 APF-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 524
Query: 2177 ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2236
A+CGG ++ G + SP +P Y QDC W V V I + +L D +T++
Sbjct: 525 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLF 583
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRV 2290
DG ++ + Q G + S+ + ++F + GF + +
Sbjct: 584 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 643
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
C PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ- 700
Query: 2351 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2410
+ CA + G+ ++ F V
Sbjct: 701 -------------------------KIMTCADPGEIANGHRTA-------SDAGFPV--- 725
Query: 2411 YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CST 2467
G ++Q Y + G + +S D G K R+ A C
Sbjct: 726 --GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLN 773
Query: 2468 PESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2526
P P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 774 PGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCKVT 831
Query: 2527 SCGIPKAPTNGGILTTDYLV 2546
P GG L L+
Sbjct: 832 QTTDPSRQLEGGNLALAILL 851
Score = 207 bits (528), Expect = 1e-52
Identities = 186/714 (26%), Positives = 298/714 (41%), Gaps = 82/714 (11%)
Query: 791 CGGHFSAPSGVILSPGWPGYYKDSL---NCEWVIEAEPGHSIKITFERFQTELNYDVLEV 847
C + S G + SP +L +C + I PG+ I+I + ++L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 848 HDG--PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYS 905
G P L LL + + Q L S +N + L F + GF+IHY++ + S
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL---S 289
Query: 906 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDALC 963
C P P HG D G T +F CDSGY+L EE L+C W+ P+C A C
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 349
Query: 964 GGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1022
GG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 350 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 409
Query: 1023 GSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCEDP 1081
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C P
Sbjct: 410 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 467
Query: 1082 GIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAEC 1137
+ + + G TFSC GY LE + I C+ W+ P C A C
Sbjct: 468 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 527
Query: 1138 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1197
G + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 528 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 587
Query: 1198 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CED 1252
+ +L G R LSS L L+F + G +GF L + + C +
Sbjct: 588 PSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 646
Query: 1253 PGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAE 1309
P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 647 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMT 704
Query: 1310 CGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVW 1368
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 705 CADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT---- 752
Query: 1369 DGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPG 1428
P +D + K A+++ C +PG
Sbjct: 753 GTPKWSDRVPK--------------------------------CALKYE-----PCLNPG 775
Query: 1429 VPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
VP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 776 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 828
Score = 206 bits (524), Expect = 3e-52
Identities = 190/781 (24%), Positives = 318/781 (40%), Gaps = 96/781 (12%)
Query: 1317 ESSGRILSPGYPFPYDNNLR---CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1373
E G + SP P L C + I V PG + +Q + ++L + G
Sbjct: 179 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 238
Query: 1374 NDMLLKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
+ S++ EG + S N + + F + GF I + + + + C P P
Sbjct: 239 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPA 297
Query: 1432 NGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGS 1491
+G + PG T F CD GY+LQGEE + C+ R W P C+A CGG + +
Sbjct: 298 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 356
Query: 1492 S-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPL 1550
+ G I+SP + C W I + L F S++ + D L + G SP+
Sbjct: 357 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 416
Query: 1551 IGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP----GNIMN 1605
I +PER + S + ++++ S+ + L ++A + CF P GN+
Sbjct: 417 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV-- 474
Query: 1606 GTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGWNRALPSCHAPCGSRS 1662
T +Y+ G+ T+ C GY L+ + + C+ D P WN P+C A CG
Sbjct: 475 -TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACKAMCGGEL 531
Query: 1663 TGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS 1722
+ G VLSP++P++YS G +CV+ + V +E + Q D++ ++DG +
Sbjct: 532 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSAR 591
Query: 1723 LLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVYQAVPRTSSTQCSSVP 1778
+L+ L G L LSSG +T++F + P +GF ++ VPR + C +P
Sbjct: 592 VLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELP 648
Query: 1779 EPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1836
P +G R + + G+ + + C PGY L GS + C QW+ S C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--------QWDLSWSAAPPACQ 700
Query: 1837 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSLDFYDGG 1895
I+T ++ G+ D P G+ +Q + + ++ E
Sbjct: 701 KIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGYSLE------------ 740
Query: 1896 DNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPS 1955
A L YS D + A+ + C P P
Sbjct: 741 --GAAMLTCYS--------------------RDTGTPKWSDRVPKCALKYEPCLNPGVPE 778
Query: 1956 SGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMS 2012
+G + Y G+ + F C +G+ L G ITC+PG +W P+C + Q
Sbjct: 779 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSR 838
Query: 2013 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETST 2072
G GN ++ + + +G GV++ + +++ + SGS S
Sbjct: 839 QLEG--------GNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGF----SGSHSYSP 886
Query: 2073 V 2073
+
Sbjct: 887 I 887
Score = 204 bits (519), Expect = 1e-51
Identities = 180/667 (26%), Positives = 280/667 (41%), Gaps = 41/667 (6%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSL---DCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
C +S+ G + SP +L DCT++I++ G+G+ +Q + + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 2064 RSGSSE--TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2121
G S ++ S L S T+ L+F S GF I YQAY L
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGF 292
Query: 2122 DPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGG 2181
PRP +G V D G T +F C GY L G L CL+G +WN P C A CGG
Sbjct: 293 PPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGG 351
Query: 2182 NI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPD 2240
I A G I SP C W++ G ++++F + + D + V G
Sbjct: 352 TIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGS 411
Query: 2241 QNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRVCQPPPPVP 2298
SP I + E + S + + ++ S+ + + L + A++ C P +
Sbjct: 412 PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF-LA 470
Query: 2299 NAEILTEDDEFEIGDIIRYQCLPGFTLVG----NAILTCRLGERLQMDGAPPVCQVLCPA 2354
+ + T D E+ G + + CLPG+ L NAI C + P C+ +C
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEPACKAMC-G 528
Query: 2355 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2414
EL + GV+LSP +P SY Q C W + V++ I + VE +E D+L ++DG
Sbjct: 529 GELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGDMLTLFDGD 586
Query: 2415 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPES---- 2470
+ VL L G + S+G ++ LQ+ A G G ++ + P +
Sbjct: 587 GPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 645
Query: 2471 ---PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2525
PP + + G L +V+ + C+ G+ L+G C+ +W A PACQ
Sbjct: 646 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWSAAPPACQK 701
Query: 2526 I-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2582
I +C P NG +D + VG+ V Y C GY L + T + GT ++
Sbjct: 702 IMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV 761
Query: 2583 PRCVV--ISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSS--GLW 2636
P+C + C P NG + + Y G + F C GF L+G C+ W
Sbjct: 762 PKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 821
Query: 2637 SESETRC 2643
+ C
Sbjct: 822 TSQPPLC 828
Score = 182 bits (463), Expect = 4e-45
Identities = 155/571 (27%), Positives = 239/571 (41%), Gaps = 31/571 (5%)
Query: 1137 CGASATNNEGILLSPNYPLNYENNH---ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1193
C + + EG + SP+ +C YSI V G GI I +T +L+Q + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1194 DGKDKTTHLLGAFTGASM--RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1251
G +SM G L S +N+L L F S GF++ Y ++ LS C
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 291
Query: 1252 DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECG 1311
P P G +S G T + C+ GY L G L C+ G R +W+ PSC+A CG
Sbjct: 292 FPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 350
Query: 1312 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1371
G + GRI+SP NL C W+IE G + L F + +D L V G
Sbjct: 351 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 410
Query: 1372 PENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1430
++ + +PE G+ S + ++ ++ + +++F + C P +
Sbjct: 411 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 470
Query: 1431 M-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCIAPCGG 1486
N T PG F C PGY L+ I C+ + W + P C A CGG
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKAMCGG 529
Query: 1487 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1546
L+ +G +LSP++P Y +DC W + V + I L ++ D L ++DG
Sbjct: 530 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 588
Query: 1547 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ESC--FD 1599
++ ++ + + R+ SS + L F++ GF L +K R ++C
Sbjct: 589 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 648
Query: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH---- 1655
P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMT 704
Query: 1656 -APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1685
A G + G T +P V + C+
Sbjct: 705 CADPGEIANGHR-TASDAGFPVGSHVQYRCL 734
Score = 171 bits (432), Expect = 2e-41
Identities = 193/787 (24%), Positives = 301/787 (38%), Gaps = 119/787 (15%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSR---DCDWTITVNADYVISLAFISFSIEPNYDFLYI 1540
C N++ G++ SP+ P + DC ++I V Y I + + ++ + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1541 YDGPD--------SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1592
G +NS ++G Q + P +N + L F+S GF + Y+A
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSP------TNRLLLHFQSPRVPRGGGFRIHYQAY 286
Query: 1593 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
L SC P +G D G T T++CD+GY LQG TL C+ G RP WN P
Sbjct: 287 LL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 343
Query: 1653 SCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---H 1708
SC A CG + G ++SP +VG N + F + SL +
Sbjct: 344 SCMASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 401
Query: 1709 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
D + V G + S ++ E +S + + S P ++A
Sbjct: 402 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF-- 459
Query: 1769 TSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQ 1823
+C + P G E+ G+ F C PGY L AI C V +
Sbjct: 460 -EEDRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPH 515
Query: 1824 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1883
WND+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 516 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNV 574
Query: 1884 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLE 1939
D L +DG +A L G L S+ +L L FQ+ GF L
Sbjct: 575 REGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH 634
Query: 1940 YTAIGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 1996
+ + D+CPE P G + + G V+++QC+ GY L G +TC W
Sbjct: 635 FKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSW 692
Query: 1997 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2056
+ P C I++ PG + P+G H+Q+ +
Sbjct: 693 SAAPPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYS 738
Query: 2057 IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2116
+ + S +T T K + A +
Sbjct: 739 LEGAAMLTCYSRDTGTP-------------------------------KWSDRVPKCALK 767
Query: 2117 LQSCPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
+ C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P
Sbjct: 768 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 827
Query: 2175 CEA---------LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQ 2225
C+ L GGN+ I P LV + G+G+YI +T LQ
Sbjct: 828 CKVTQTTDPSRQLEGGNLAL---AILLP------------LGLV-IVLGSGVYIYYTKLQ 871
Query: 2226 TEPIYDF 2232
+ ++ F
Sbjct: 872 GKSLFGF 878
Score = 167 bits (422), Expect = 2e-40
Identities = 138/556 (24%), Positives = 231/556 (41%), Gaps = 23/556 (4%)
Query: 444 CGSNLQGPSGTFTSPNFPFQYDSNA---QCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
C +N+ G SP+ C + I V I+I + +L + L
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIH-VYPGYGIEIQVQTLNLSQEEELLV 231
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
+ GG G +L + ++ S ++++ LH Q+ GF+++Y+ SC
Sbjct: 232 LAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SC 290
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 618
G P P +G F C G++L GE++++C + W+ P C+ C
Sbjct: 291 GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 350
Query: 619 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 677
A +G ++SP+ G NL C W I + G R+HL F L+ D L V+ G
Sbjct: 351 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 410
Query: 678 SPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 736
SP SP++ +VP L S++ L +E ++ + ++ + F + C P +
Sbjct: 411 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 470
Query: 737 I-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH 794
N ++ G+ + C G+ ++ G + + W+ P C A CGG
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE 530
Query: 795 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 854
S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 531 LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPS 589
Query: 855 SPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLDPG 910
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 590 ARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPELP 648
Query: 911 IPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG-- 964
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 708
Query: 965 GDVRGPSGTILSPGYP 980
G++ T G+P
Sbjct: 709 GEIANGHRTASDAGFP 724
Score = 131 bits (330), Expect = 1e-29
Identities = 154/572 (26%), Positives = 231/572 (40%), Gaps = 68/572 (11%)
Query: 65 CGGTLKGLNGTIESP--GFPYGYPNGA-NCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
C + G +ESP G P G +CT+ I I+I Q+ L +E + L L
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 122 YDGHPHPTNFRTRLTGFHLPPP--VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
G R L + S + L S GF+++Y+ S CG
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 291
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
P P G + T G + C +GY L G L C+ + SW+ P C A
Sbjct: 292 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCMA-- 347
Query: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 297
+CGGT+ ++ G I SP N C W I A G + L F ++E D L +
Sbjct: 348 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 407
Query: 298 EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSR 353
G P P I+ S M+ P +IS+ L + ++++ S ++ + + R
Sbjct: 408 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE----EDR 463
Query: 354 GFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV 413
F F L G + T DP ++ G+ FSC Y
Sbjct: 464 CFAPF-----------LAHGNVTTT-----DP-----------EYRPGALATFSCLPGYA 496
Query: 414 LQ---GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQC 470
L+ +I C E W+D P CK CG L P+G SP++P Y C
Sbjct: 497 LEPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDC 553
Query: 471 VWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMS 530
VW + V K I + E ++ G D LT+ DG G VL L G ++S
Sbjct: 554 VWGV-HVQEEKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLLSSG 609
Query: 531 SQMWLHLQT-----DESVGSVGFKVNYKEIEK-ESCGDPGTPLYGIR---EGDGFSNRDV 581
+ L Q + +G GF +++KE+ + ++C + P +G R GD V
Sbjct: 610 PDLTLQFQAPPGPPNPGLGQ-GFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTV 667
Query: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
L ++C+ G+EL+G + CQ + WSA P C
Sbjct: 668 LTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Score = 128 bits (321), Expect = 1e-28
Identities = 132/581 (22%), Positives = 224/581 (38%), Gaps = 88/581 (15%)
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNA---DCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
C + G + SP + DCT++I PG I + + ++ + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 298 EGSEPPTIWLSGMNIPPPIISNK-------------NWLRLHFVTDSNHRYRGFSAPYQV 344
G P + P +++N N L LHF + R GF YQ
Sbjct: 233 AGGGSP-------GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 285
Query: 345 KKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTV 404
+L+ C P P +G +D G T
Sbjct: 286 Y-----------------------LLS----------CGFPPRPAHGDVSVTDLHPGGTA 312
Query: 405 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GTFTSPNFPFQ 463
F CD Y LQG +++ C + +W+ P C + +CG + + G SP
Sbjct: 313 TFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-MASCGGTIHNATLGRIVSPEPGGA 369
Query: 464 YDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP 523
N C WVI A + + ++FE L+ D L + GG P V+ S +
Sbjct: 370 VGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGSPLSP-----VIYDSDMD 423
Query: 524 DL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGD-GFSN 578
D+ ++S + +++ L ++ + + ++ E++ C P + D +
Sbjct: 424 DVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRP 483
Query: 579 RDVLRFECQFGFELI---GEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDY 633
+ F C G+ L +I C + + W+ P C C + P G VLSPD+
Sbjct: 484 GALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDW 543
Query: 634 PEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVP 693
P+ Y +C+W + RI L ++ + D L + DGD P + +L G +
Sbjct: 544 PQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPR 602
Query: 694 SHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFGHNE-CPDPGIPINARRFGDNFQL 748
L S+ L L+FQA + G+GF + + N+ CP+ P R + L
Sbjct: 603 RRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDL 662
Query: 749 --GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
G+ ++ CE G+ + G++ +TC + WS P C
Sbjct: 663 IRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPAC 699
Score = 92.0 bits (227), Expect = 9e-18
Identities = 106/445 (23%), Positives = 163/445 (36%), Gaps = 75/445 (16%)
Query: 54 TVSCVKGFIYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFAL 112
T SC+ +CGGT+ G I SP C WVI A E R+ + F+ +L
Sbjct: 342 TPSCMA----SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSL 397
Query: 113 EEEYDYLSLYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 170
+E+ D L + G P + + + ++ +S++ + L S+ + + +
Sbjct: 398 DEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRF 456
Query: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTA 226
E + C P + V + G +SC+ GY L+ G P + C+
Sbjct: 457 EAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEP 514
Query: 227 SWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF 286
W+ P C+A CGG + +G++ SP +P Y DC W + + I L
Sbjct: 515 HWNDTEPACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEIL 572
Query: 287 QMEEKYDYLEIEGSEPPTIWLSGMNIPPP---IISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
+ E +G P L+ + P P ++S+ L L F G +
Sbjct: 573 NVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFV 632
Query: 344 VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASN----------------------- 380
+ FK P D + E G +TAS+
Sbjct: 633 LH---------FKEVPRNDTCPELP-PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 682
Query: 381 ---------------------LCPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGA 417
C DPGE NG R SD F +GS VQ+ C Y L+GA
Sbjct: 683 ILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGA 742
Query: 418 KSITCQRIAEVFAAWSDHRPVCKVK 442
+TC WSD P C +K
Sbjct: 743 AMLTCYSRDTGTPKWSDRVPKCALK 767
Score = 89.0 bits (219), Expect = 8e-17
Identities = 62/203 (30%), Positives = 85/203 (41%), Gaps = 12/203 (5%)
Query: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 641 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 700
Query: 2823 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 2875
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 701 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 760
Query: 2876 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 2931
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 761 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 819
Query: 2932 SWTGRQPECKAVQCGNPGTTANG 2954
WT + P CK Q +P G
Sbjct: 820 QWTSQPPLCKVTQTTDPSRQLEG 842
Score = 85.9 bits (211), Expect = 7e-16
Identities = 63/195 (32%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 2950 TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIISCGDPG 3008
T ++G + R GT + Y C GY L G + C + +WS P C I++C DPG
Sbjct: 656 TASHGDLIR--GTVLT----YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG 709
Query: 3009 IPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGT----WSGVMPTC--R 3060
ANG R D + VG +V Y C PGY++E G+ + TC T WS +P C +
Sbjct: 710 EIANGHRTASDAGFPVGSHVQYRCLPGYSLE--GAAMLTCYSRDTGTPKWSDRVPKCALK 767
Query: 3061 AVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTWSGEVPQ 3116
C P NG L ++ G S+ + C G+EL +TCV W+ + P
Sbjct: 768 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 827
Query: 3117 CLPKFCGDPGIPAQG 3131
C DP +G
Sbjct: 828 CKVTQTTDPSRQLEG 842
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3063 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3119
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 643 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 3120 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3173
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 3174 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3230
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 763 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 821
Query: 3231 SGIQPEC 3237
+ P C
Sbjct: 822 TSQPPLC 828
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2667 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2722
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 664 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 723
Query: 2723 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2776
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 724 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 783
Query: 2777 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2821
H + G + + C G+ L G + C P QW P C
Sbjct: 784 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 828
Score = 73.6 bits (179), Expect = 3e-12
Identities = 63/245 (25%), Positives = 97/245 (39%), Gaps = 37/245 (15%)
Query: 2589 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA- 2645
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 643 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 2646 GHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHN----WSGQLP 2699
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 2700 SCVPV--SCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2753
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 763 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 822
Query: 2754 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTY--------------GTVVFYDCNPGYF 2799
PP+CKV +DP ++E GN G ++Y G
Sbjct: 823 SQPPLCKVTQTTDP--------SRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKS 874
Query: 2800 LFGSS 2804
LFG S
Sbjct: 875 LFGFS 879
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/136 (32%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 2827 GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 2886
G PG+ P + + G + S T + L QS R + G Q + +
Sbjct: 236 GSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 289
Query: 2887 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKAV 2943
CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA- 347
Query: 2944 QCGNPGTTANGKVFRI 2959
CG GT N + RI
Sbjct: 348 SCG--GTIHNATLGRI 361
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3178 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3236
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 639 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 698
Query: 3237 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3289
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 699 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 754
Query: 3290 --WTGKVPIC 3297
W+ +VP C
Sbjct: 755 PKWSDRVPKC 764
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 173 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 766 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 823
Query: 231 PVPICR 236
P+C+
Sbjct: 824 QPPLCK 829
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
Query: 3062 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3118
++C PP+ ++G + T+ G + ++ C GY+L L C+ NGT W+GE P C+
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCM 346
Query: 3119 PKFCG 3123
CG
Sbjct: 347 AS-CG 350
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 555 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 610
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 766 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 825
Query: 611 PIC 613
P+C
Sbjct: 826 PLC 828
Score = 40.8 bits (94), Expect = 0.024
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2587 VISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2644
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Query: 2645 AGHCGIPELIVNGQVIGENYG 2665
A G G+++ G
Sbjct: 347 ASCGGTIHNATLGRIVSPEPG 367
Score = 40.4 bits (93), Expect = 0.031
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3182 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3238
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 289 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Score = 40.4 bits (93), Expect = 0.031
Identities = 39/148 (26%), Positives = 55/148 (37%), Gaps = 27/148 (18%)
Query: 1595 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 769 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 826
Query: 1653 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1712
C V P G N +I +P V+ L V
Sbjct: 827 LC-------------KVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 864
Query: 1713 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1740
+Y Q SL SGSHS + + S
Sbjct: 865 IYYTKLQGKSLF-GFSGSHSYSPITVES 891
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3001 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3057
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 343
Query: 3058 TCRAVTCPTPPQISNGRL 3075
+C A T + GR+
Sbjct: 344 SCMASCGGTIHNATLGRI 361
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2648 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD--HNWSGQLPSCVPVS 2705
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 348
Query: 2706 CG 2707
CG
Sbjct: 349 CG 350
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 382 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 771 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 828
Query: 440 KV 441
KV
Sbjct: 829 KV 830
Score = 35.8 bits (81), Expect = 0.77
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2704 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2759
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Score = 35.0 bits (79), Expect = 1.3
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 2820 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 2876
+ ++ CG P P + +S G T + C L G+ + C LNG W+G
Sbjct: 284 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGET 342
Query: 2877 PHCSGDATGT 2886
P C GT
Sbjct: 343 PSCMASCGGT 352
Score = 34.3 bits (77), Expect = 2.2
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3241 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3298
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 289 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 346
Query: 3299 A 3299
A
Sbjct: 347 A 347
Score = 32.7 bits (73), Expect = 6.5
Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 3444 MSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVHEN 3501
+++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 830 VTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSP 886
Query: 3502 NNGQAAFENPMYD 3514
++ F NP+Y+
Sbjct: 887 ITVESDFSNPLYE 899
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 208 bits (529), Expect = 9e-53
Identities = 189/718 (26%), Positives = 286/718 (39%), Gaps = 79/718 (11%)
Query: 1830 TCIVPCGGILTKRKGTILSPGYPEPYDNNL---NCVWKITVPEGAGIQVQVVSFATEHNW 1886
T V C +++ +G + SP P L +C + I V G GI++QV +
Sbjct: 98 TSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEE 157
Query: 1887 DSLDFYDGGDNN-APRLGSYSGTTIP-HLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIG 1944
+ L GG APRL + S +L S +N L L+FQS GF + Y A
Sbjct: 158 ELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYL 217
Query: 1945 LDSCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
L SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C
Sbjct: 218 L-SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 2004 LAQCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLE 2062
+A CGG + + + G I+SP G +L C W I G +HL F S + +D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 2063 VRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2121
VRSG S S VI +P L S + S+ N + ++A++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 2122 DPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCE 2176
P +G V D + G +F C PGY L +A+ C+ +WN P C+
Sbjct: 396 APF-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 454
Query: 2177 ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2236
A+CGG ++ G + SP +P Y QDC W V V I + +L D +T++
Sbjct: 455 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLF 513
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRV 2290
DG ++ + Q G + S+ + ++F + GF + +
Sbjct: 514 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 573
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
C PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ- 630
Query: 2351 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2410
+ CA + G+ ++ F V
Sbjct: 631 -------------------------KIMTCADPGEIANGHRTA-------SDAGFPV--- 655
Query: 2411 YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CST 2467
G ++Q Y + G + +S D G K R+ A C
Sbjct: 656 --GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLN 703
Query: 2468 PESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
P P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 704 PGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCK 759
Score = 207 bits (528), Expect = 1e-52
Identities = 186/714 (26%), Positives = 298/714 (41%), Gaps = 82/714 (11%)
Query: 791 CGGHFSAPSGVILSPGWPGYYKDSL---NCEWVIEAEPGHSIKITFERFQTELNYDVLEV 847
C + S G + SP +L +C + I PG+ I+I + ++L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 848 HDG--PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYS 905
G P L LL + + Q L S +N + L F + GF+IHY++ + S
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL---S 219
Query: 906 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDALC 963
C P P HG D G T +F CDSGY+L EE L+C W+ P+C A C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 279
Query: 964 GGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITEN 1022
GG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 1023 GSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCEDP 1081
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C P
Sbjct: 340 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 397
Query: 1082 GIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAEC 1137
+ + + G TFSC GY LE + I C+ W+ P C A C
Sbjct: 398 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 457
Query: 1138 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD 1197
G + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 458 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 517
Query: 1198 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CED 1252
+ +L G R LSS L L+F + G +GF L + + C +
Sbjct: 518 PSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 576
Query: 1253 PGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAE 1309
P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 577 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMT 634
Query: 1310 CGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVW 1368
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT---- 682
Query: 1369 DGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPG 1428
P +D + K A+++ C +PG
Sbjct: 683 GTPKWSDRVPK--------------------------------CALKYE-----PCLNPG 705
Query: 1429 VPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
VP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 706 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 758
Score = 206 bits (524), Expect = 3e-52
Identities = 190/786 (24%), Positives = 317/786 (40%), Gaps = 93/786 (11%)
Query: 1317 ESSGRILSPGYPFPYDNNLR---CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1373
E G + SP P L C + I V PG + +Q + ++L + G
Sbjct: 109 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 168
Query: 1374 NDMLLKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
+ S++ EG + S N + + F + GF I + + + + C P P
Sbjct: 169 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPA 227
Query: 1432 NGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGS 1491
+G + PG T F CD GY+LQGEE + C+ R W P C+A CGG + +
Sbjct: 228 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 286
Query: 1492 S-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPL 1550
+ G I+SP + C W I + L F S++ + D L + G SP+
Sbjct: 287 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 346
Query: 1551 IGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP----GNIMN 1605
I +PER + S + ++++ S+ + L ++A + CF P GN+
Sbjct: 347 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV-- 404
Query: 1606 GTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGWNRALPSCHAPCGSRS 1662
T +Y+ G+ T+ C GY L+ + + C+ D P WN P+C A CG
Sbjct: 405 -TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHWNDTEPACKAMCGGEL 461
Query: 1663 TGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS 1722
+ G VLSP++P++YS G +CV+ + V +E + Q D++ ++DG +
Sbjct: 462 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSAR 521
Query: 1723 LLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVYQAVPRTSSTQCSSVP 1778
+L+ L G L LSSG +T++F + P +GF ++ VPR + C +P
Sbjct: 522 VLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELP 578
Query: 1779 EPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1836
P +G R + + G+ + + C PGY L GS + C QW+ S C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--------QWDLSWSAAPPACQ 630
Query: 1837 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSLDFYDGG 1895
I+T ++ G+ D P G+ +Q + + ++ E
Sbjct: 631 KIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGYSLE------------ 670
Query: 1896 DNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPS 1955
A L YS D + A+ + C P P
Sbjct: 671 --GAAMLTCYS--------------------RDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 1956 SGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSD 2013
+G + Y G+ + F C +G+ L G ITC+PG +W P+C + +
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDN 768
Query: 2014 FSGVILSPGFPGNYPSSLDCTWTINLPIGF------GVHLQFVNFSTETIHDYLEVRSGS 2067
+ P + I LP+G GV++ + +++ + SGS
Sbjct: 769 RKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGF----SGS 824
Query: 2068 SETSTV 2073
S +
Sbjct: 825 HSYSPI 830
Score = 204 bits (519), Expect = 1e-51
Identities = 180/667 (26%), Positives = 280/667 (41%), Gaps = 41/667 (6%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSL---DCTWTINLPIGFGVHLQFVNFSTETIHDYLEV 2063
C +S+ G + SP +L DCT++I++ G+G+ +Q + + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2064 RSGSSE--TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCP 2121
G S ++ S L S T+ L+F S GF I YQAY L
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGF 222
Query: 2122 DPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGG 2181
PRP +G V D G T +F C GY L G L CL+G +WN P C A CGG
Sbjct: 223 PPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGG 281
Query: 2182 NI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPD 2240
I A G I SP C W++ G ++++F + + D + V G
Sbjct: 282 TIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGS 341
Query: 2241 QNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRVCQPPPPVP 2298
SP I + E + S + + ++ S+ + + L + A++ C P +
Sbjct: 342 PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF-LA 400
Query: 2299 NAEILTEDDEFEIGDIIRYQCLPGFTLVG----NAILTCRLGERLQMDGAPPVCQVLCPA 2354
+ + T D E+ G + + CLPG+ L NAI C + P C+ +C
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEPACKAMC-G 458
Query: 2355 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2414
EL + GV+LSP +P SY Q C W + V++ I + VE +E D+L ++DG
Sbjct: 459 GELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGDMLTLFDGD 516
Query: 2415 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPES---- 2470
+ VL L G + S+G ++ LQ+ A G G ++ + P +
Sbjct: 517 GPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 575
Query: 2471 ---PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2525
PP + + G L +V+ + C+ G+ L+G C+ +W A PACQ
Sbjct: 576 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWSAAPPACQK 631
Query: 2526 I-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2582
I +C P NG +D + VG+ V Y C GY L + T + GT ++
Sbjct: 632 IMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV 691
Query: 2583 PRCVV--ISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSS--GLW 2636
P+C + C P NG + + Y G + F C GF L+G C+ W
Sbjct: 692 PKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 751
Query: 2637 SESETRC 2643
+ C
Sbjct: 752 TSQPPLC 758
Score = 182 bits (463), Expect = 4e-45
Identities = 155/571 (27%), Positives = 239/571 (41%), Gaps = 31/571 (5%)
Query: 1137 CGASATNNEGILLSPNYPLNYENNH---ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1193
C + + EG + SP+ +C YSI V G GI I +T +L+Q + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1194 DGKDKTTHLLGAFTGASM--RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1251
G +SM G L S +N+L L F S GF++ Y ++ LS C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 1252 DPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECG 1311
P P G +S G T + C+ GY L G L C+ G R +W+ PSC+A CG
Sbjct: 222 FPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1312 GRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1371
G + GRI+SP NL C W+IE G + L F + +D L V G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1372 PENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVP 1430
++ + +PE G+ S + ++ ++ + +++F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1431 M-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCIAPCGG 1486
N T PG F C PGY L+ I C+ + W + P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKAMCGG 459
Query: 1487 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1546
L+ +G +LSP++P Y +DC W + V + I L ++ D L ++DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1547 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ESC--FD 1599
++ ++ + + R+ SS + L F++ GF L +K R ++C
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH---- 1655
P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMT 634
Query: 1656 -APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1685
A G + G T +P V + C+
Sbjct: 635 CADPGEIANGHR-TASDAGFPVGSHVQYRCL 664
Score = 170 bits (431), Expect = 2e-41
Identities = 192/786 (24%), Positives = 300/786 (38%), Gaps = 104/786 (13%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSR---DCDWTITVNADYVISLAFISFSIEPNYDFLYI 1540
C N++ G++ SP+ P + DC ++I V Y I + + ++ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1541 YDGPD--------SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1592
G +NS ++G Q + P +N + L F+S GF + Y+A
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSP------TNRLLLHFQSPRVPRGGGFRIHYQAY 216
Query: 1593 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
L SC P +G D G T T++CD+GY LQG TL C+ G RP WN P
Sbjct: 217 LL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 273
Query: 1653 SCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---H 1708
SC A CG + G ++SP +VG N + F + SL +
Sbjct: 274 SCMASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 331
Query: 1709 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
D + V G + S ++ E +S + + S P ++A
Sbjct: 332 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF-- 389
Query: 1769 TSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQ 1823
+C + P G E+ G+ F C PGY L AI C V +
Sbjct: 390 -EEDRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPH 445
Query: 1824 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATE 1883
WND+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 446 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNV 504
Query: 1884 HNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLE 1939
D L +DG +A L G L S+ +L L FQ+ GF L
Sbjct: 505 REGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH 564
Query: 1940 YTAIGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 1996
+ + D+CPE P G + + G V+++QC+ GY L G +TC W
Sbjct: 565 FKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSW 622
Query: 1997 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2056
+ P C I++ PG + P+G H+Q+ +
Sbjct: 623 SAAPPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYS 668
Query: 2057 IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2116
+ + S +T T K + A +
Sbjct: 669 LEGAAMLTCYSRDTGTP-------------------------------KWSDRVPKCALK 697
Query: 2117 LQSCPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
+ C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 2175 C-----EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWL---VRVPPGNGIYINFTVLQT 2226
C E L + T P E N L + + G+G+YI +T LQ
Sbjct: 758 CKVAYEELLDNRKLEVTQTT--DPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQG 815
Query: 2227 EPIYDF 2232
+ ++ F
Sbjct: 816 KSLFGF 821
Score = 167 bits (422), Expect = 2e-40
Identities = 138/556 (24%), Positives = 231/556 (41%), Gaps = 23/556 (4%)
Query: 444 CGSNLQGPSGTFTSPNFPFQYDSNA---QCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
C +N+ G SP+ C + I V I+I + +L + L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIH-VYPGYGIEIQVQTLNLSQEEELLV 161
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
+ GG G +L + ++ S ++++ LH Q+ GF+++Y+ SC
Sbjct: 162 LAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SC 220
Query: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 618
G P P +G F C G++L GE++++C + W+ P C+ C
Sbjct: 221 GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 619 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 677
A +G ++SP+ G NL C W I + G R+HL F L+ D L V+ G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 678 SPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP 736
SP SP++ +VP L S++ L +E ++ + ++ + F + C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 737 I-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH 794
N ++ G+ + C G+ ++ G + + W+ P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE 460
Query: 795 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 854
S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 461 LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPS 519
Query: 855 SPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLDPG 910
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 520 ARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPELP 578
Query: 911 IPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG-- 964
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Query: 965 GDVRGPSGTILSPGYP 980
G++ T G+P
Sbjct: 639 GEIANGHRTASDAGFP 654
Score = 131 bits (330), Expect = 1e-29
Identities = 154/572 (26%), Positives = 231/572 (40%), Gaps = 68/572 (11%)
Query: 65 CGGTLKGLNGTIESP--GFPYGYPNGA-NCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
C + G +ESP G P G +CT+ I I+I Q+ L +E + L L
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 122 YDGHPHPTNFRTRLTGFHLPPP--VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
G R L + S + L S GF+++Y+ S CG
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CG 221
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
P P G + T G + C +GY L G L C+ + SW+ P C A
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCMA-- 277
Query: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 297
+CGGT+ ++ G I SP N C W I A G + L F ++E D L +
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 298 EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSR 353
G P P I+ S M+ P +IS+ L + ++++ S ++ + + R
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE----EDR 393
Query: 354 GFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV 413
F F L G + T DP ++ G+ FSC Y
Sbjct: 394 CFAPF-----------LAHGNVTTT-----DP-----------EYRPGALATFSCLPGYA 426
Query: 414 LQ---GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQC 470
L+ +I C E W+D P CK CG L P+G SP++P Y C
Sbjct: 427 LEPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDC 483
Query: 471 VWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMS 530
VW + V K I + E ++ G D LT+ DG G VL L G ++S
Sbjct: 484 VWGV-HVQEEKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLLSSG 539
Query: 531 SQMWLHLQT-----DESVGSVGFKVNYKEIEK-ESCGDPGTPLYGIR---EGDGFSNRDV 581
+ L Q + +G GF +++KE+ + ++C + P +G R GD V
Sbjct: 540 PDLTLQFQAPPGPPNPGLGQ-GFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTV 597
Query: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
L ++C+ G+EL+G + CQ + WSA P C
Sbjct: 598 LTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Score = 128 bits (321), Expect = 1e-28
Identities = 132/581 (22%), Positives = 224/581 (38%), Gaps = 88/581 (15%)
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNA---DCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
C + G + SP + DCT++I PG I + + ++ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 298 EGSEPPTIWLSGMNIPPPIISNK-------------NWLRLHFVTDSNHRYRGFSAPYQV 344
G P + P +++N N L LHF + R GF YQ
Sbjct: 163 AGGGSP-------GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 215
Query: 345 KKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTV 404
+L+ C P P +G +D G T
Sbjct: 216 Y-----------------------LLS----------CGFPPRPAHGDVSVTDLHPGGTA 242
Query: 405 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GTFTSPNFPFQ 463
F CD Y LQG +++ C + +W+ P C + +CG + + G SP
Sbjct: 243 TFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-MASCGGTIHNATLGRIVSPEPGGA 299
Query: 464 YDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP 523
N C WVI A + + ++FE L+ D L + GG P V+ S +
Sbjct: 300 VGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGSPLSP-----VIYDSDMD 353
Query: 524 DL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGD-GFSN 578
D+ ++S + +++ L ++ + + ++ E++ C P + D +
Sbjct: 354 DVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRP 413
Query: 579 RDVLRFECQFGFELI---GEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDY 633
+ F C G+ L +I C + + W+ P C C + P G VLSPD+
Sbjct: 414 GALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDW 473
Query: 634 PEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVP 693
P+ Y +C+W + RI L ++ + D L + DGD P + +L G +
Sbjct: 474 PQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPR 532
Query: 694 SHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFGHNE-CPDPGIPINARRFGDNFQL 748
L S+ L L+FQA + G+GF + + N+ CP+ P R + L
Sbjct: 533 RRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDL 592
Query: 749 --GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
G+ ++ CE G+ + G++ +TC + WS P C
Sbjct: 593 IRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPAC 629
Score = 94.7 bits (234), Expect = 1e-18
Identities = 60/170 (35%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 3019 DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV-TCPTPPQISNGRLEG 3077
D + G ++Y C+PGY EL GS I TC + +WS P C+ + TC P +I+NG
Sbjct: 591 DLIRGTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA 648
Query: 3078 TN--FDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKF--CGDPGIPA 3129
++ F G + Y C PGY L A+LTC G WS VP+C K+ C +PG+P
Sbjct: 649 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 3130 QGKREGKSFIYQS--EVSFSCNFPFILVGSSTRICQA--DGTWSGSSPHC 3175
G + YQ+ + F C F L+G T C W+ P C
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 92.0 bits (227), Expect = 9e-18
Identities = 106/445 (23%), Positives = 163/445 (36%), Gaps = 75/445 (16%)
Query: 54 TVSCVKGFIYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFAL 112
T SC+ +CGGT+ G I SP C WVI A E R+ + F+ +L
Sbjct: 272 TPSCMA----SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSL 327
Query: 113 EEEYDYLSLYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 170
+E+ D L + G P + + + ++ +S++ + L S+ + + +
Sbjct: 328 DEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRF 386
Query: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTA 226
E + C P + V + G +SC+ GY L+ G P + C+
Sbjct: 387 EAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEP 444
Query: 227 SWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF 286
W+ P C+A CGG + +G++ SP +P Y DC W + + I L
Sbjct: 445 HWNDTEPACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEIL 502
Query: 287 QMEEKYDYLEIEGSEPPTIWLSGMNIPPP---IISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
+ E +G P L+ + P P ++S+ L L F G +
Sbjct: 503 NVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFV 562
Query: 344 VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASN----------------------- 380
+ FK P D + E G +TAS+
Sbjct: 563 LH---------FKEVPRNDTCPELP-PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 612
Query: 381 ---------------------LCPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGA 417
C DPGE NG R SD F +GS VQ+ C Y L+GA
Sbjct: 613 ILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGA 672
Query: 418 KSITCQRIAEVFAAWSDHRPVCKVK 442
+TC WSD P C +K
Sbjct: 673 AMLTCYSRDTGTPKWSDRVPKCALK 697
Score = 88.2 bits (217), Expect = 1e-16
Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 16/189 (8%)
Query: 2886 TCGDPGTPGHGSRQESN--FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC-KA 2942
TC + P G R S+ + + Y C+ GY L GS+ TC + SW+ P C K
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 2943 VQCGNPGTTANGKVFRID-GTTFSSSVIYSCMEGYILSGPSVRQCTANGT----WSGTLP 2997
+ C +PG ANG D G S V Y C+ GY L G ++ C + T WS +P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 2998 NCTI--ISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN--GT 3051
C + C +PG+P NG + Y Y G+++ + C G+ EL G TC
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGF--ELIGEVTITCVPGHPSQ 750
Query: 3052 WSGVMPTCR 3060
W+ P C+
Sbjct: 751 WTSQPPLCK 759
Score = 84.0 bits (206), Expect = 2e-15
Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 571 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 630
Query: 2823 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 2875
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 631 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 690
Query: 2876 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 2931
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 691 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 749
Query: 2932 SWTGRQPECK 2941
WT + P CK
Sbjct: 750 QWTSQPPLCK 759
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3063 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3119
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 3120 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3173
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 3174 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3230
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 693 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 751
Query: 3231 SGIQPEC 3237
+ P C
Sbjct: 752 TSQPPLC 758
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2667 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2722
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 594 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 653
Query: 2723 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2776
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 654 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 713
Query: 2777 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2821
H + G + + C G+ L G + C P QW P C
Sbjct: 714 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 67.8 bits (164), Expect = 2e-10
Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 15/188 (7%)
Query: 2589 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA- 2645
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 2646 GHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHN----WSGQLP 2699
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 2700 SCVPV--SCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2753
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 2754 HPPPMCKV 2761
PP+CKV
Sbjct: 753 SQPPLCKV 760
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/136 (32%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 2827 GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGT 2886
G PG+ P + + G + S T + L QS R + G Q + +
Sbjct: 166 GSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 219
Query: 2887 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKAV 2943
CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA- 277
Query: 2944 QCGNPGTTANGKVFRI 2959
CG GT N + RI
Sbjct: 278 SCG--GTIHNATLGRI 291
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3178 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3236
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 569 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 628
Query: 3237 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3289
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 684
Query: 3290 --WTGKVPIC 3297
W+ +VP C
Sbjct: 685 PKWSDRVPKC 694
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 173 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 753
Query: 231 PVPICR 236
P+C+
Sbjct: 754 QPPLCK 759
Score = 43.9 bits (102), Expect = 0.003
Identities = 39/148 (26%), Positives = 56/148 (37%), Gaps = 14/148 (9%)
Query: 1595 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 699 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 756
Query: 1653 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1712
C + V P G N +I +P V+ L V
Sbjct: 757 LCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 807
Query: 1713 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1740
+Y Q SL SGSHS + + S
Sbjct: 808 IYYTKLQGKSLF-GFSGSHSYSPITVES 834
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
Query: 3062 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3118
++C PP+ ++G + T+ G + ++ C GY+L L C+ NGT W+GE P C+
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCM 276
Query: 3119 PKFCG 3123
CG
Sbjct: 277 AS-CG 280
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 555 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 610
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 755
Query: 611 PIC 613
P+C
Sbjct: 756 PLC 758
Score = 40.8 bits (94), Expect = 0.024
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2587 VISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2644
++SCG P P +G+ T G TA F CD G+ L G CL+ W+ C+
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2645 AGHCGIPELIVNGQVIGENYG 2665
A G G+++ G
Sbjct: 277 ASCGGTIHNATLGRIVSPEPG 297
Score = 40.4 bits (93), Expect = 0.031
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3182 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3238
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 219 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 39.7 bits (91), Expect = 0.054
Identities = 19/66 (28%), Positives = 29/66 (43%)
Query: 2285 AYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA 2344
A + C P N ++ G+ +R+ C GF L+G +TC G Q
Sbjct: 695 ALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 754
Query: 2345 PPVCQV 2350
PP+C+V
Sbjct: 755 PPLCKV 760
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3001 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3057
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 273
Query: 3058 TCRAVTCPTPPQISNGRL 3075
+C A T + GR+
Sbjct: 274 SCMASCGGTIHNATLGRI 291
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2648 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSCVPVS 2705
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 278
Query: 2706 CG 2707
CG
Sbjct: 279 CG 280
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 382 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 701 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 758
Query: 440 KV 441
KV
Sbjct: 759 KV 760
Score = 35.8 bits (81), Expect = 0.77
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2704 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2759
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 35.0 bits (79), Expect = 1.3
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 2820 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQ 2876
+ ++ CG P P + +S G T + C L G+ + C LNG W+G
Sbjct: 214 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGET 272
Query: 2877 PHCSGDATGT 2886
P C GT
Sbjct: 273 PSCMASCGGT 282
Score = 34.3 bits (77), Expect = 2.2
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3241 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3298
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 276
Query: 3299 A 3299
A
Sbjct: 277 A 277
Score = 34.3 bits (77), Expect = 2.2
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 3442 LNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVH 3499
L +++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 771 LEVTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSY 827
Query: 3500 ENNNGQAAFENPMYD 3514
++ F NP+Y+
Sbjct: 828 SPITVESDFSNPLYE 842
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 206 bits (525), Expect = 3e-52
Identities = 122/401 (30%), Positives = 183/401 (45%), Gaps = 21/401 (5%)
Query: 2688 CQQDHNWSG----QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK 2743
C+ D +SG Q+ +C + GS + GN F++N + SC+ GYL
Sbjct: 163 CKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGN-FSYNSSCSISCDRGYLPSSMET 221
Query: 2744 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2803
QC ++ +WS P P C VV C PAN E G+F + T +DC G+ L G+
Sbjct: 222 MQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGA 281
Query: 2804 SVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVL------SGEKYTFGSTVHYSCTGKRS 2857
L C +G WD P C + C P N + +GE +TF S+ +++C
Sbjct: 282 QSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGE-FTFKSSCNFTCEEGFM 340
Query: 2858 LLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDP--GTPGHGSRQESNFRTKSTVRYACDT 2915
L G + C G W+ P C +P G +FR S+ ++C+
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQ 400
Query: 2916 GYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKV----FRIDGTTFSSSVIYS 2971
G++L GS+ C G W +P C+AV+C G V I T+ SS +S
Sbjct: 401 GFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFS 460
Query: 2972 CMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPAN-GLRYGDDYVVGQNVSYMC 3030
C EG+ L G + +CT+ G W+ +P+C ++ C +P + + V G + C
Sbjct: 461 CEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFAC 520
Query: 3031 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS 3071
G+T LNGS RTC G WSG++PTC A T P ++
Sbjct: 521 PEGWT--LNGSAARTCGATGHWSGLLPTCEAPTESNIPLVA 559
Score = 172 bits (435), Expect = 7e-42
Identities = 110/378 (29%), Positives = 167/378 (44%), Gaps = 28/378 (7%)
Query: 2524 QAISCGIPKAPTNGGILTT----DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2579
Q ++C ++P +G ++ + ++ + + C+ GY SS E T C S G WS
Sbjct: 176 QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME--TMQCMSSGEWSA- 232
Query: 2580 NKTPRCVVISCGELPTPPNGNKIGTQTS----YGSTAIFTCDLGFMLVGSAVRECLSSGL 2635
P C V+ C + P NG Q + +T F C+ GF L+G+ +C SSG
Sbjct: 233 -PIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN 291
Query: 2636 WSESETRCLAGHCGIPELIVNGQV------IGENYGYRDTVVYQCNPGFRLIGSSVRICQ 2689
W + C A C NG V GE + ++ + + C GF L G + C
Sbjct: 292 WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGE-FTFKSSCNFTCEEGFMLQGPAQVECT 350
Query: 2690 QDHNWSGQLPSCVPVSCGHPGSPIYG-----RTSGNGFNFNDVVTFSCNIGYLMQGPTKA 2744
W+ Q+P C C +P G ++ F + FSC G++++G +
Sbjct: 351 TQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRL 410
Query: 2745 QCQANRQWSHPPPMCKVVNCSDPGIPANS-KRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2803
QC +W + P C+ V C P R + G FTY + + C G+ L GS
Sbjct: 411 QCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGS 470
Query: 2804 SVLICQPNGQWDKPLPECIMIDCGHPGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQ 2861
+ L C GQW + +P C ++ C VP N SGE FG+ ++C +L G
Sbjct: 471 TQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP-VFGTVCKFACPEGWTLNGS 529
Query: 2862 SSRTCQLNGHWSGSQPHC 2879
++RTC GHWSG P C
Sbjct: 530 AARTCGATGHWSGLLPTC 547
Score = 164 bits (415), Expect = 1e-39
Identities = 120/434 (27%), Positives = 174/434 (40%), Gaps = 42/434 (9%)
Query: 2884 TGTCGDPGTPGHGSRQES--NFRTKSTVRYACDTGYI-LHGSEERTCLANGSWTGRQPEC 2940
T C + GHG E+ N+ K CD G+ L + C A S PE
Sbjct: 140 TAACTNTSCSGHGECVETINNYTCK------CDPGFSGLKCEQIVNCTALES-----PEH 188
Query: 2941 KAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCT 3000
++ C +P + +++SS SC GY+ S QC ++G WS +P C
Sbjct: 189 GSLVCSHP----------LGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 3001 IISCGDPGIPANGL----RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVM 3056
++ C PANG + + ++ C+ G+ EL G++ CT +G W
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGF--ELMGAQSLQCTSSGNWDNEK 296
Query: 3057 PTCRAVTCPTPPQISNGRLEGTN-----FDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3111
PTC+AVTC Q NG + ++ F + S ++ C G+ L PA + C G W+
Sbjct: 297 PTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWT 356
Query: 3112 GEVPQCLPKFCGDPGIPAQG-----KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADG 3166
++P C C P +G SF Y S FSC F+L GS C G
Sbjct: 357 QQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTG 416
Query: 3167 TWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFG-FQVGSVVQFHCKKGHLLQGSTTRTCL 3225
W P C + P ++ G F S F C++G L GST C
Sbjct: 417 EWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECT 476
Query: 3226 PDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCR 3285
W+ P C C P N+ P G + C G+ L G+ R C
Sbjct: 477 SQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTL-NGSAARTCG 535
Query: 3286 SDNTWTGKVPICEA 3299
+ W+G +P CEA
Sbjct: 536 ATGHWSGLLPTCEA 549
Score = 163 bits (412), Expect = 3e-39
Identities = 107/379 (28%), Positives = 156/379 (41%), Gaps = 33/379 (8%)
Query: 2465 CSTPESPPHGYII-SQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVP 2521
C+ ESP HG ++ S G NS +CDRG+ + C S W AP+P
Sbjct: 180 CTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSG----EWSAPIP 235
Query: 2522 ACQAISCGIPKAPTNGGI----LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2577
AC + C P NG + + T T+ C +G+ L + + C S G W
Sbjct: 236 ACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQ--SLQCTSSGNWD 293
Query: 2578 NHNKTPRCVVISCGELPTPPNG-----NKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLS 2632
N+ P C ++C + P NG + + ++ S+ FTC+ GFML G A EC +
Sbjct: 294 --NEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTT 351
Query: 2633 SGLWSESETRCLAGHCGIPELIVNGQV-----IGENYGYRDTVVYQCNPGFRLIGSSVRI 2687
G W++ C A C G + ++ Y + + C GF L GS
Sbjct: 352 QGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQ 411
Query: 2688 CQQDHNWSGQLPSCVPVSCGHPGSPIYG-----RTSGNGFNFNDVVTFSCNIGYLMQGPT 2742
C W + P+C V C P G + F + FSC G+ + G T
Sbjct: 412 CGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGST 471
Query: 2743 KAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG 2802
+ +C + QW+ P C+VV CS +P G +GTV + C G+ L G
Sbjct: 472 QLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCS---GEPVFGTVCKFACPEGWTLNG 528
Query: 2803 SSVLICQPNGQWDKPLPEC 2821
S+ C G W LP C
Sbjct: 529 SAARTCGATGHWSGLLPTC 547
Score = 159 bits (402), Expect = 5e-38
Identities = 107/385 (27%), Positives = 159/385 (41%), Gaps = 37/385 (9%)
Query: 2819 PECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRT--CQLNGHWSGSQ 2876
PE + C HP +++ S+ SC R L S T C +G WS
Sbjct: 186 PEHGSLVCSHPL---------GNFSYNSSCSISCD--RGYLPSSMETMQCMSSGEWSAPI 234
Query: 2877 PHCSGDATGTCGDPGTPGHGS----RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 2932
P C+ C P +G + +F +T + C+ G+ L G++ C ++G+
Sbjct: 235 PACN---VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN 291
Query: 2933 WTGRQPECKAVQCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTA 2988
W +P CKAV C NG V TF SS ++C EG++L GP+ +CT
Sbjct: 292 WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTT 351
Query: 2989 NGTWSGTLPNCTIISCGDPGIPANGLRY-----GDDYVVGQNVSYMCQPGYTMELNGSRI 3043
G W+ +P C C P G + G + + C+ G+ L GS+
Sbjct: 352 QGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFV--LKGSKR 409
Query: 3044 RTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN-----FDWGFSISYICSPGYELSF 3098
C G W PTC AV C Q G + + F + S ++ C G+EL
Sbjct: 410 LQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHG 469
Query: 3099 PAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSF-IYQSEVSFSCNFPFILVGS 3157
L C G W+ EVP C C +P + ++ + F+C + L GS
Sbjct: 470 STQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGS 529
Query: 3158 STRICQADGTWSGSSPHCIEPTQTS 3182
+ R C A G WSG P C PT+++
Sbjct: 530 AARTCGATGHWSGLLPTCEAPTESN 554
Score = 78.6 bits (192), Expect = 1e-13
Identities = 54/194 (27%), Positives = 81/194 (41%), Gaps = 18/194 (9%)
Query: 2462 AFYCSTPESPPHGY---IISQTGG-QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2517
AF C+ +P GY + S +G + S ++C++GF L G C + WD
Sbjct: 364 AFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTG----EWD 419
Query: 2518 APVPACQAISCGIPKAPTNGGILTTDYLVG-----TRVTYFCNDGYRLSSKELTTAVCQS 2572
P C+A+ C P G + +G + + C +G+ L T C S
Sbjct: 420 NEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGS--TQLECTS 477
Query: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECL 2631
G W+ + P C V+ C L P N + +G+ F C G+ L GSA R C
Sbjct: 478 QGQWTE--EVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCG 535
Query: 2632 SSGLWSESETRCLA 2645
++G WS C A
Sbjct: 536 ATGHWSGLLPTCEA 549
Score = 75.5 bits (184), Expect = 9e-13
Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Query: 3137 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3196
+F Y S S SC+ ++ T C + G WS P C + NP N
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQN 258
Query: 3197 TFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGM 3256
F + F C++G L G+ + C W +P C +C+ P + +V
Sbjct: 259 PGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCS 318
Query: 3257 DLPSHGYTLI----YTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3308
P+ +T +TC+ GF L G + C + WT ++P+CEA + +P
Sbjct: 319 HSPAGEFTFKSSCNFTCEEGFMLQGPAQVE-CTTQGQWTQQIPVCEAFQCTALSNP 373
Score = 57.0 bits (136), Expect = 3e-07
Identities = 103/471 (21%), Positives = 165/471 (35%), Gaps = 115/471 (24%)
Query: 888 SNNGFKIHYESV-TVNTYSC-LDPGI----------------PVHGRRY-GH---DFSIG 925
+N H E V T+N Y+C DPG P HG H +FS
Sbjct: 144 TNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYN 203
Query: 926 STVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPN 985
S+ S SCD GY S E + C + WS P+P C+ + V P+ G+ E + N
Sbjct: 204 SSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPAN-----GFVECFQN 258
Query: 986 SLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGL 1045
+ W TF E+ + L G+ ++G
Sbjct: 259 PGSFPWNTTC-----------TFDCEEGFE----------------LMGAQSLQCTSSGN 291
Query: 1046 YGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS-----RIGFNFGIGDTL 1100
+ N + + ++ C PQ GS F +
Sbjct: 292 WDNEKPTCKAVT--------------------CRAVRQPQNGSVRCSHSPAGEFTFKSSC 331
Query: 1101 TFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA-ECGASATNNEGIL-LSPNYPLNYE 1158
F+C G+ L+G +++ C G+ W+ +P C A +C A + G + P+ ++
Sbjct: 332 NFTCEEGFMLQGPAQVECTTQGQ--WTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFR 389
Query: 1159 NNHECIYSIQV-------------QAGKGINISARTFHLAQGDVLKIYDGKDKTTHL-LG 1204
C +S + G+ N + V + G + H +G
Sbjct: 390 YGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIG 449
Query: 1205 AFTGASM------RGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP-Q 1257
FT S G L ++ LE S + T+E S ++ C +P +
Sbjct: 450 EFTYKSSCAFSCEEGFELHGSTQ---LECTSQGQWTEE-----VPSCQVVKCSSLAVPGK 501
Query: 1258 FGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
S + F G+ + C G+TL+GS+ C G W LP+C A
Sbjct: 502 INMSCSGEPVF-GTVCKFACPEGWTLNGSAARTC--GATGHWSGLLPTCEA 549
Score = 52.4 bits (124), Expect = 8e-06
Identities = 65/276 (23%), Positives = 107/276 (38%), Gaps = 40/276 (14%)
Query: 1617 STVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYP 1675
+T T+ C+ G+ L G +L C + W+ P+C A C + G+V + P
Sbjct: 266 TTCTFDCEEGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVRQPQNGSVRCSHSP 321
Query: 1676 KN-YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSG- 1733
++ +C ++ + F++ G T+ + P ++ ++LS G
Sbjct: 322 AGEFTFKSSCNFTCE--EGFMLQGPAQVECTTQGQWTQQI--PVCEAFQCTALSNPERGY 377
Query: 1734 -ESLPLSSGN---QITIRFTSVGPITAKGFHFVY--------QAVPRTSSTQCSSVPEPR 1781
LP +SG+ + F+ KG + P + +C +V +P
Sbjct: 378 MNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPP 437
Query: 1782 FG------RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVP 1834
G IG EF SS F C G+ LHGS + C S QW + +P+C +V
Sbjct: 438 KGLVRCAHSPIG-EFTYKSSCAFSCEEGFELHGSTQLEC----TSQGQWTEEVPSCQVVK 492
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEG 1870
C + K + G P V K PEG
Sbjct: 493 CSSLAVPGKINMSCSGEPV-----FGTVCKFACPEG 523
Score = 51.2 bits (121), Expect = 2e-05
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 63/251 (25%)
Query: 382 CPDPGEPENG-----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHR 436
C PE G F GS+ +FSC++ +VL+G+K + C E W + +
Sbjct: 367 CTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGE----WDNEK 422
Query: 437 PVCKVKTCGSNLQGPSGTFTSPNFPF-QYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG 495
P C+ C + Q P G + P ++ + C + E F+L G
Sbjct: 423 PTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE------------EGFELH-G 469
Query: 496 YDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEI 555
L G+ + QV+ S + +V K+N
Sbjct: 470 STQLECTSQGQWTEEVPSCQVVKCSSL----------------------AVPGKINM--- 504
Query: 556 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 615
SC G P++G V +F C G+ L G + C WS +P C
Sbjct: 505 ---SCS--GEPVFG----------TVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEA 549
Query: 616 PCLSNFTAPMG 626
P SN G
Sbjct: 550 PTESNIPLVAG 560
Score = 50.4 bits (119), Expect = 3e-05
Identities = 40/154 (25%), Positives = 56/154 (36%), Gaps = 11/154 (7%)
Query: 3162 CQADGTWSGSSPHCIEPTQTSCENPGVPRHGS---QNNTFGFQVGSVVQFHCKKGHLLQG 3218
C+ D +SG I +C P HGS + F S C +G+L
Sbjct: 163 CKCDPGFSGLKCEQI----VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSS 218
Query: 3219 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH---GYTLIYTCQPGFFL 3275
T C+ WS P C C PA+ V P T + C+ GF L
Sbjct: 219 METMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFEL 278
Query: 3276 AGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPR 3309
G + C S W + P C+A + V+ P+
Sbjct: 279 MGAQSLQ-CTSSGNWDNEKPTCKAVTCRAVRQPQ 311
Score = 48.1 bits (113), Expect = 2e-04
Identities = 69/287 (24%), Positives = 97/287 (33%), Gaps = 65/287 (22%)
Query: 398 FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ-------- 449
F +T F C+E + L GA+S+ C W + +P CK TC + Q
Sbjct: 262 FPWNTTCTFDCEEGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVRQPQNGSVRC 317
Query: 450 --GPSGTFT---SPNF----------PFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 494
P+G FT S NF P Q + Q W + + Q + E
Sbjct: 318 SHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWT-QQIPVCEAFQCTALS-NPER 375
Query: 495 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESV--GSVGFKVNY 552
GY L +GSF S + L+ + + G G N
Sbjct: 376 GY--------------MNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNE 421
Query: 553 KEI-EKESCGDPGTPLYGIRE------GDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ 605
K E C P G+ G+ F+ + F C+ GFEL G + C Q
Sbjct: 422 KPTCEAVRCDAVHQPPKGLVRCAHSPIGE-FTYKSSCAFSCEEGFELHGSTQLECTSQGQ 480
Query: 606 WSANIPICIFPCLSNFTAP------------MGTVLSPDYPEGYGNN 640
W+ +P C S+ P GTV PEG+ N
Sbjct: 481 WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLN 527
Score = 46.6 bits (109), Expect = 4e-04
Identities = 64/268 (23%), Positives = 104/268 (38%), Gaps = 32/268 (11%)
Query: 729 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG 788
E P+ G + + G NF SS S+ C+ G++ + ET+ C + G+ WS IP C
Sbjct: 184 ESPEHGSLVCSHPLG-NFSYNSSCSISCDRGYLPS-SMETMQC-MSSGE--WSAPIPACN 238
Query: 789 -APCGGHFSAPSGVI---LSPG-WPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYD 843
C + +G + +PG +P + +CE E S++ T + N+D
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCT-----SSGNWD 293
Query: 844 ----VLEVHDGPNLLSPLLGSYNGTQVP--QFLFSSS-NFI----YLLFTTDNSRSNNGF 892
+ + P GS + P +F F SS NF ++L
Sbjct: 294 NEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQG 353
Query: 893 KIHYESVTVNTYSCLDPGIPVHG-----RRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE 947
+ + + C P G F GS+ FSC+ G+ L + L C
Sbjct: 354 QWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCG 413
Query: 948 KNHWWSHPLPTCDAL-CGGDVRGPSGTI 974
W + PTC+A+ C + P G +
Sbjct: 414 PTGEWDNEKPTCEAVRCDAVHQPPKGLV 441
Score = 45.1 bits (105), Expect = 0.001
Identities = 101/460 (21%), Positives = 145/460 (31%), Gaps = 118/460 (25%)
Query: 382 CPDPGEPENGKRIGS----DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 437
C PE+G + S +FS S+ SCD Y+ +++ C E WS P
Sbjct: 180 CTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE----WSAPIP 235
Query: 438 VCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 497
C V C + +G P + N C FD E G++
Sbjct: 236 ACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT------------------FDCEEGFE 277
Query: 498 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEK 557
M +Q LQ S K K +
Sbjct: 278 L------------------------------MGAQ---SLQCTSSGNWDNEKPTCKAVTC 304
Query: 558 ESCGDP--GTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC-I 614
+ P G+ F+ + F C+ GF L G + C QW+ IP+C
Sbjct: 305 RAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEA 364
Query: 615 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
F C T LS + GY +NC + S GS + S +F E F K
Sbjct: 365 FQC---------TALS-NPERGY---MNC---LPSASGSFRYGSSCEFSCEQGFVLKGSK 408
Query: 675 ----------DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMS---GRGFNIT 721
D + P + + P L +H EF S + GF +
Sbjct: 409 RLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELH 468
Query: 722 YNTFGHNECPDPG-----IP---------------INARRFGDNFQLGSSISVICEEGFI 761
+T EC G +P IN G+ G+ C EG+
Sbjct: 469 GST--QLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPV-FGTVCKFACPEGW- 524
Query: 762 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV 801
G+ TC WSGL+P C AP + +G+
Sbjct: 525 TLNGSAARTC---GATGHWSGLLPTCEAPTESNIPLVAGL 561
Score = 43.1 bits (100), Expect = 0.005
Identities = 96/448 (21%), Positives = 148/448 (33%), Gaps = 100/448 (22%)
Query: 1774 CSSVPEPRFGRRI-----GNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSL 1828
C+++ P G + GN F+ SS C+ GY+ ++C S +W+ +
Sbjct: 180 CTALESPEHGSLVCSHPLGN-FSYNSSCSISCDRGYLPSSMETMQCM----SSGEWSAPI 234
Query: 1829 PTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQ-VQVVSFATEHNW 1886
P C +V C + G + P + N C + EG + Q + + NW
Sbjct: 235 PACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCE--EGFELMGAQSLQCTSSGNW 292
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946
D N P + + + N + S S AG E+T
Sbjct: 293 D---------NEKPTCKAVTCRAVRQPQNGSVR---------CSHSPAG---EFTF--KS 329
Query: 1947 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPI---- 2002
SC +F C++G+ LQG + + C +W IP+
Sbjct: 330 SC----------------------NFTCEEGFMLQGPAQVECTTQG--QWTQQIPVCEAF 365
Query: 2003 --------------CLAQCGGAMSDFSGVILS--PGFPGNYPSSLDC----TWTINLPIG 2042
CL G+ S S GF L C W P
Sbjct: 366 QCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
Query: 2043 FGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2102
V V+ + + VR S IG + S FS L+ +
Sbjct: 426 EAVRCDAVHQPPKGL-----VRCAHSP----IGEFTYKS--SCAFSCEEGFELHGSTQLE 474
Query: 2103 QNKQG-FHIVYQAYQLQSCPDPR-PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC 2160
QG + + Q+ C P + + G F C G+TL G++A TC
Sbjct: 475 CTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTC 534
Query: 2161 LHGVSRNWNHPLPRCEALCGGNITAMNG 2188
G + +W+ LP CEA NI + G
Sbjct: 535 --GATGHWSGLLPTCEAPTESNIPLVAG 560
Score = 43.1 bits (100), Expect = 0.005
Identities = 60/292 (20%), Positives = 100/292 (34%), Gaps = 68/292 (23%)
Query: 1766 VPRTSSTQCSSVPEPRFGR----RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1821
+P + +C +V P G + F ++ FDC G+ L G+ +++C S
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQC----TSS 289
Query: 1822 AQWNDSLPTC-IVPCGGILTKRKGTIL---SPGYPEPYDNNLNCVWKITVPEGAGIQVQV 1877
W++ PTC V C + + G++ SP + ++ N T EG +Q
Sbjct: 290 GNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCN----FTCEEGFMLQGPA 345
Query: 1878 -VSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 1936
V T+ W P ++ T + S Y+N S S
Sbjct: 346 QVECTTQGQW---------TQQIPVCEAFQCTAL-----SNPERGYMNCLPSASGS---- 387
Query: 1937 HLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW 1996
+ G F C+QG+ L+G + C GP W
Sbjct: 388 ---------------------------FRYGSSCEFSCEQGFVLKGSKRLQC--GPTGEW 418
Query: 1997 NYPIPICLA-QCGGAMSDFSGVILSPGFP-GNYPSSLDCTWTINLPIGFGVH 2046
+ P C A +C G++ P G + C ++ GF +H
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE--EGFELH 468
Score = 43.1 bits (100), Expect = 0.005
Identities = 49/224 (21%), Positives = 76/224 (33%), Gaps = 63/224 (28%)
Query: 1613 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLS 1671
++ GS+ + C+ G+VL+G L C G G W+ P+C A C + +G V
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQC--GPTGE--WDNEKPTCEAVRCDAVHQPPKGLVRC 443
Query: 1672 PNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSH 1731
+ P G+F + + E ++ H
Sbjct: 444 AHSP---------------------IGEFTYKSSCAFSCEEGFE--------------LH 468
Query: 1732 SGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEP-RFGRRIGNEF 1790
L +S Q T + VP +CSS+ P + E
Sbjct: 469 GSTQLECTSQGQWT------------------EEVPSCQVVKCSSLAVPGKINMSCSGEP 510
Query: 1791 AVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1834
G+ F C G+ L+GS A C + W+ LPTC P
Sbjct: 511 VFGTVCKFACPEGWTLNGSAARTC----GATGHWSGLLPTCEAP 550
Score = 34.7 bits (78), Expect = 1.7
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 2128 NGFVI----GNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGN 2182
NGFV F T +F+C G+ L+G +L C S NW++ P C+A+ C
Sbjct: 250 NGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTS--SGNWDNEKPTCKAVTCRAV 307
Query: 2183 ITAMNGTI 2190
NG++
Sbjct: 308 RQPQNGSV 315
Score = 32.7 bits (73), Expect = 6.5
Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 194 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIIS 253
F G +SC G++L G +L C T WD P C A C + G++
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQC----GPTGEWDNEKPTCEAV-RCDAVHQPPKGLVR 442
Query: 254 SPSFP-NEYHNNADCTWT 270
P E+ + C ++
Sbjct: 443 CAHSPIGEFTYKSSCAFS 460
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 199 bits (505), Expect = 5e-50
Identities = 166/645 (25%), Positives = 272/645 (42%), Gaps = 122/645 (18%)
Query: 444 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 499
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
Query: 500 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 559
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 619
C P G E + + C G+EL +K C C
Sbjct: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
Query: 620 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 675
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
Query: 676 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 735
G + +S + G F G+E P +TS + +R+EF++D+++S +GF + + +EC
Sbjct: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDEC----- 707
Query: 736 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHF 795
S + C++ + T G+ C G V+ A C
Sbjct: 708 --------------SKDNGGCQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHKV 751
Query: 796 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNYDVLEVHDGP 851
++ SG I SP WP Y C W I + PGH +K+TF Q E YD LEV DG
Sbjct: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
Query: 852 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 911
+ +P+LG + G++ P+ + ++ + ++L F +DNS GF+
Sbjct: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA----------------- 854
Query: 912 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 971
H G V + SH + GD P
Sbjct: 855 -------SHATECGGQVRADVKTKDLYSHAQ---------------------FGDNNYPG 886
Query: 972 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSFTQ 1027
G ++C W + G GV+ F TF +E+ +DY+ + + T
Sbjct: 887 G--------------VDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTA 932
Query: 1028 P-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
P L R GS P + + ++F SD +I+ +GF++ ++
Sbjct: 933 PRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
Score = 196 bits (498), Expect = 3e-49
Identities = 134/452 (29%), Positives = 218/452 (48%), Gaps = 56/452 (12%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 1950
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
Query: 1951 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
P ++ + + S++C D GY L P +R C A CG
Sbjct: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
Query: 2009 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2064
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2065 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2124
SG + S + G+ G + P + S + + F SD + +K+GF + + + + D
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD-- 710
Query: 2125 PFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNIT 2184
NG + + +C G+ L N H EA C +T
Sbjct: 711 ---NGGCQQDCVNTFGSYECQCRSGFVLHDNK-----HDCK----------EAGCDHKVT 752
Query: 2185 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL----QTEPIYDFITVWDGPD 2240
+ +GTI SP +PD+YP+ ++C W + PG+ + + F + Q E YD + V+DG D
Sbjct: 753 STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRD 812
Query: 2241 QNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2272
+P +G+F G+ E V +T +++ ++F+SD
Sbjct: 813 AKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
Score = 192 bits (489), Expect = 4e-48
Identities = 174/648 (26%), Positives = 270/648 (41%), Gaps = 126/648 (19%)
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1189
A CG + G + SPNYP +Y + CI+ IQV G + ++ ++F + + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
L++ DG +++ L+G + G + STS++LWL+F SD GF + + E+
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 1250 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
C P + ++ G + S C+PGY L +RR C A
Sbjct: 551 CSRPNRGGCEQRCLNTLGSYKCS-----CDPGYEL--------APDKRR--------CEA 589
Query: 1309 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1364
CGG F + +G I SPG+P Y N C+W + +SLQF F+TE + +D
Sbjct: 590 ACGG-FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1365 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
+ V G + L + GS PE I S N + ++F +D +SK GF F S
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
Query: 1425 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
+D G N G + QC G+ L + + C + A C
Sbjct: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLH-DNKHDCKE---------------AGC 747
Query: 1485 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1540
+T +SG I SPN+P YP ++C W I+ + + L F+ IE YD L +
Sbjct: 748 DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEV 807
Query: 1541 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1600
+DG D+ +P++G F SK PE + ++ + M L F SD SV GF + +
Sbjct: 808 FDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATEC------- 860
Query: 1601 GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS 1660
G ++ D K T Y A + GD+ PG
Sbjct: 861 -----GGQVRADVK---TKDLYSHAQF------------GDNNYPG-------------- 886
Query: 1661 RSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-----HDVVEVYD 1715
G +C + I + + V F F+ +D +E++D
Sbjct: 887 --------------------GVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
Query: 1716 GPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
G + L GS E + S+G+ + ++F S IT KGFH Y
Sbjct: 927 GYDSTAPRLGRYCGSGPPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 187 bits (475), Expect = 2e-46
Identities = 173/681 (25%), Positives = 275/681 (40%), Gaps = 161/681 (23%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
N G + L + + SC GY L + R E
Sbjct: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 295
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 296 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFK 351
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF--------- 700
Query: 352 SRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDED 411
F KD +K +NG + + + C
Sbjct: 701 ------FSDKDECSK----------------------DNGGCQQDCVNTFGSYECQCRSG 732
Query: 412 YVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCV 471
+VL D++ CK C + SGT TSPN+P +Y S +C
Sbjct: 733 FVLH------------------DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECT 774
Query: 472 WVITAVNTNKVIQINFEEFDL----EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIV 527
W I++ ++V ++ F E D+ E YD L + DG + P VL GS P+ ++
Sbjct: 775 WAISSTPGHRV-KLTFMEMDIESQPECAYDHLEVFDGRDAKAP--VLGRFCGSKKPEPVL 831
Query: 528 SMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQ 587
+ S+M+L +D SV GF+ ++ CG G ++ D +S+ Q
Sbjct: 832 ATGSRMFLRFYSDNSVQRKGFQASH----ATECG--GQVRADVKTKDLYSH-------AQ 878
Query: 588 FGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 647
FG +NN YP G ++C W I
Sbjct: 879 FG------------DNN----------------------------YPGG----VDCEWVI 894
Query: 648 ISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
+++ G + L F F++E + +D++ + DG +P LG + G+ P + S +
Sbjct: 895 VAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSV 954
Query: 704 RLEFQADHSMSGRGFNITYNT 724
++F +D +++ +GF++ Y +
Sbjct: 955 LVKFHSDDTITKKGFHLRYTS 975
Score = 184 bits (468), Expect = 1e-45
Identities = 145/465 (31%), Positives = 212/465 (45%), Gaps = 56/465 (12%)
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2121 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
RP R G T+G + C PGY L + RCEA CG
Sbjct: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
Query: 2181 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2236
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP 2296
G +S G+F G+ E + S N + ++F SD T S ++ C
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
Query: 2297 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2356
+ + +E QC GF L N + D C +
Sbjct: 713 GCQQDCVNTFGSYEC------QCRSGFVLHDN-----------KHDCKEAGC------DH 749
Query: 2357 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF---FQTEKEFDVLQVYD 2412
++G I SP +PD YP+ + C W+IS G+ + + F+E Q E +D L+V+D
Sbjct: 750 KVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFD 809
Query: 2413 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2457
G + ++PVL G + + G +FL++ +D+ +KGF+
Sbjct: 810 GRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 182 bits (463), Expect = 4e-45
Identities = 142/478 (29%), Positives = 212/478 (44%), Gaps = 73/478 (15%)
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1598 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
P R G + + +T+ Y CD GY L P R C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
Query: 1655 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1710
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1711 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1767
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
Query: 1768 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1827
+ +CS + N F S C G++LH D+
Sbjct: 702 -SDKDECSK-DNGGCQQDCVNTFG---SYECQCRSGFVLH------------------DN 738
Query: 1828 LPTCI-VPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1885
C C +T GTI SP +P+ Y + C W I+ G +++ + E
Sbjct: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
Query: 1886 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 1940
+D L+ +DG D AP LG + G+ P + +T + ++L F SD SV GF +
Sbjct: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
Score = 166 bits (421), Expect = 3e-40
Identities = 132/466 (28%), Positives = 198/466 (42%), Gaps = 59/466 (12%)
Query: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1710
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1771 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
S E R +G S C+PGY E P+
Sbjct: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
Query: 1831 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1886
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + + D
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKD 705
Query: 1947 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQ 2006
C + +G D QC G+ L + H C A
Sbjct: 706 EC----SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------AG 746
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDYLE 2062
C ++ SG I SP +P YPS +CTW I+ G V L F+ E+ +D+LE
Sbjct: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2108
V G + V+GR G + P + +T L F+SD S ++GF
Sbjct: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
Score = 152 bits (384), Expect = 6e-36
Identities = 201/779 (25%), Positives = 288/779 (36%), Gaps = 186/779 (23%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CG TL+ G SP +P GY +C W I +I + F S L YDY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
+ DG R R G LP P+ ST S + S GF YE + CG
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----CGG 437
Query: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
DV + Y D P CI W V
Sbjct: 438 --------------DVKKDYGHIQSPNYPDDYRPSKVCI--------WRIQV-------- 467
Query: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG- 299
G ++ SF E H++ YDYLE+
Sbjct: 468 ----SEGFHVGLTFQSFEIERHDSC-------------------------AYDYLEVRDG 498
Query: 300 -SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
SE T+ G P I S + L L FV+D + GF+ + K +D SR
Sbjct: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVDECSRP-- 554
Query: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
N GG C + +LGS + SCD Y L
Sbjct: 555 --------------NRGG---CEQRCLN--------------TLGS-YKCSCDPGYELAP 582
Query: 417 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 476
K C+ CG L +G+ TSP +P +Y N C+W + A
Sbjct: 583 DKR-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA 623
Query: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDLIVSMSSQ 532
T I + F+ F+ E G D D EV T L G F P++I S +
Sbjct: 624 -PTQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNN 680
Query: 533 MWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFEL 592
M + ++D +V GFK ++ + E D G G ++ D + +C+ GF L
Sbjct: 681 MRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQCRSGFVL 735
Query: 593 IGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPG 652
K C+E C T+ GT+ SP++P+ Y + C W I S PG
Sbjct: 736 HDNKH-DCKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPG 782
Query: 653 SRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 708
R+ L+F + D+ESQ +D L V DG ++P+LG F G++ P + + + L F
Sbjct: 783 HRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFY 842
Query: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINA----------RRFGDNFQLGS---SISVI 755
+D+S+ +GF ++ T EC G + A +FGDN G ++
Sbjct: 843 SDNSVQRKGFQASHAT----EC---GGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIV 895
Query: 756 CEEGF-----IKTQGTETITCILMDGKVMWSG---LIPKCGAPCGGHFSAPSGVILSPG 806
EEG+ +T E T D ++ G P+ G CG S P + S G
Sbjct: 896 AEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCG---SGPPEEVYSAG 951
Score = 151 bits (381), Expect = 1e-35
Identities = 169/679 (24%), Positives = 265/679 (39%), Gaps = 153/679 (22%)
Query: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YD 293
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 294 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
YLE+ + L G P I S + L L FV+D + GF+ + K +D
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFF--KEVD 549
Query: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
SR N GG + C + +LGS + SCD
Sbjct: 550 ECSRP----------------NRGGCEQR---CLN--------------TLGS-YKCSCD 575
Query: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Y L K C+ CG L +G+ TSP +P +Y N
Sbjct: 576 PGYELAPDKR-RCEA------------------ACGGFLTKLNGSITSPGWPKEYPPNKN 616
Query: 470 CVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDL 525
C+W + A T I + F+ F+ E G D D EV T L G F P++
Sbjct: 617 CIWQLVAP-TQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEV 673
Query: 526 IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFE 585
I S + M + ++D +V GFK ++ + E D G G ++ D + +
Sbjct: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG----GCQQ-DCVNTFGSYECQ 728
Query: 586 CQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIW 645
C+ GF L K C+E C T+ GT+ SP++P+ Y + C W
Sbjct: 729 CRSGFVLHDNKHD-CKEAG------------CDHKVTSTSGTITSPNWPDKYPSKKECTW 775
Query: 646 TIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPI--LGTFTGAEVPSHLTSNSHIL 703
I S PG R+ L+ F+ + PE L F G +
Sbjct: 776 AISSTPGHRVKLT-----------FMEMDIESQPECAYDHLEVFDGRD------------ 812
Query: 704 RLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKT 763
A + GR F ++ P+P + +R F F +S+ +GF +
Sbjct: 813 -----AKAPVLGR--------FCGSKKPEPVLATGSRMFL-RFYSDNSVQ---RKGFQAS 855
Query: 764 QGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEA 823
TE CG + Y ++CEWVI A
Sbjct: 856 HATE-------------------CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVA 896
Query: 824 EPGHSIKITFERFQ----TELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYL 879
E G+ +++ F+ F+ T+ YD +E+ DG + +P LG Y G+ P+ ++S+ + + +
Sbjct: 897 EEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLV 956
Query: 880 LFTTDNSRSNNGFKIHYES 898
F +D++ + GF + Y S
Sbjct: 957 KFHSDDTITKKGFHLRYTS 975
Score = 150 bits (379), Expect = 2e-35
Identities = 127/466 (27%), Positives = 200/466 (42%), Gaps = 60/466 (12%)
Query: 789 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 844
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 904
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF VN +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-------AVNFF 545
Query: 905 SCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 963
+D P G + + SCD GY L+ ++ C+A C
Sbjct: 546 KEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDK--------------RRCEAAC 591
Query: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLI 1019
GG + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 1020 TENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1078
+ L + GS+ P I + Y N R + F SD ++S +GF F E
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHFFSDKDECS 708
Query: 1079 EDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECG 1138
+D G Q F + C SG+ L C G C
Sbjct: 709 KDNGGCQQDCVNTFG-----SYECQCRSGFVLHDNKH-DCKEAG--------------CD 748
Query: 1139 ASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIY 1193
T+ G + SPN+P Y + EC ++I G + ++ + D L+++
Sbjct: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
Query: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ 1239
DG+D +LG F G S + + +T ++++L F SD +GFQ
Sbjct: 809 DGRDAKAPVLGRFCG-SKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 145 bits (365), Expect = 9e-34
Identities = 133/479 (27%), Positives = 201/479 (41%), Gaps = 64/479 (13%)
Query: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
++ C P R G + SC GY L RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
+ G + L G F G S + ++S N + +EF SD + +GF+ + S +
Sbjct: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
Query: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1309
+D G Q D + GS C G+ LH + + D+ + S
Sbjct: 708 SKDNGGCQ-----QDCVNTFGSYECQ-CRSGFVLHDNK----HDCKEAGCDHKVTS---- 753
Query: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA----SHDIL 1365
+SG I SP +P Y + C W I PG+ V L F+ D E+ ++D L
Sbjct: 754 --------TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
Query: 1366 RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
V+DG +L GS PE + +T + + ++F +D + + G F +S AT C
Sbjct: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG----FQASHATEC 860
Score = 100 bits (250), Expect = 2e-20
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2289
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
Query: 2290 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
C P +CL +G+ +C G L D C+
Sbjct: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
Query: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2405
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 2406 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 67.8 bits (164), Expect = 2e-10
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 1855 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 1910
Y ++C W I EG G+++ +F E +D ++ +DG D+ APRLG Y G+
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Query: 1911 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 1942
P + S +++ + F SD +++ GFHL YT+
Sbjct: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 67.4 bits (163), Expect = 2e-10
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 66.6 bits (161), Expect = 4e-10
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 2026 NYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSSETSTVIGRLSGPQ 2081
NYP +DC W I G+GV L F F T+ +DY+E+ G T+ +GR G
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
P ++S + FHSD + K+GFH+ Y + + Q
Sbjct: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
Score = 65.9 bits (159), Expect = 7e-10
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Query: 2179 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2230
CGG + A T +YS + YP DC W++ G G+ + F + E Y
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGF 2278
D++ ++DG D +P++G++ G+ E VYS + +L+KFHSD T GF
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 969
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2281
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 62.8 bits (151), Expect = 6e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 387 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 434
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
Query: 435 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 493
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
Query: 494 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
Query: 551 NYKEIEKESCGDPGTPLYG 569
Y+ I CG YG
Sbjct: 430 VYEAI----CGGDVKKDYG 444
Score = 62.4 bits (150), Expect = 8e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 59.7 bits (143), Expect = 5e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2418
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
Query: 2419 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2476
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
Query: 2477 ISQTGGQLNSVVRWACDRGFRL 2498
+ L S + +CD G+ L
Sbjct: 560 EQRCLNTLGS-YKCSCDPGYEL 580
Score = 58.5 bits (140), Expect = 1e-07
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 889 NNGFKIHYESV 899
GF YE++
Sbjct: 424 GKGFFAVYEAI 434
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1187
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1188 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Query: 1245 F-------ELSHCEDPGIP 1256
+ H + P P
Sbjct: 434 ICGGDVKKDYGHIQSPNYP 452
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
Query: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1764 QAV 1766
+A+
Sbjct: 432 EAI 434
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1361 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1414
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 50.8 bits (120), Expect = 2e-05
Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 12/121 (9%)
Query: 241 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 292
CGG +R + + S F N Y DC W IVAE G + L+F F++EE+ Y
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 293 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
DY+E+ + + P G P + S + + + F +D +GF Y K
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
Query: 349 D 349
D
Sbjct: 980 D 980
Score = 49.3 bits (116), Expect = 7e-05
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 2372 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2427
++YP C W I E+GY + + + F+ E+E +D ++++DG + +P L G
Sbjct: 882 NNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS 941
Query: 2428 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
+ S G V +++ +D KKGF +RY
Sbjct: 942 -GPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 45.4 bits (106), Expect = 0.001
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 1156 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1210
NY +C + I + G G+ + +TF + + D ++++DG D T LG + G+
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 1211 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
S+ + L ++F+SD T +GF L YTS
Sbjct: 943 PPEEVYSAGDSVL-VKFHSDDTITKKGFHLRYTS 975
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 963 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1018
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1019 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1056
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Score = 38.9 bits (89), Expect = 0.091
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
Query: 2467 TPESPPHGYIIS 2478
+G+I S
Sbjct: 437 GDVKKDYGHIQS 448
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 197 bits (502), Expect = 1e-49
Identities = 153/525 (29%), Positives = 225/525 (42%), Gaps = 67/525 (12%)
Query: 2528 CGIPK-----APTNGGILTTDYL--VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2580
C +P+ PTN LT D+ +GT + Y C GY S + +C + W++
Sbjct: 35 CNVPEWLPFARPTN---LTDDFEFPIGTYLNYECRPGY---SGRPFSIICLKNSVWTSAK 88
Query: 2581 KTPRCVVISCGELPTPPNGNK-IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LW 2636
+C SC P P NG + + S ++C G+ L+GS+ C+ SG +W
Sbjct: 89 D--KCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIW 146
Query: 2637 SESETRCLAGHCGIPELIVNGQ---VIGENYGYRDTVVYQCNPG------FRLIGSSVRI 2687
C CG+P I NG + E + Y V Y CN G F L+G
Sbjct: 147 DNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIY 206
Query: 2688 CQQDHN----WSGQLPSCV-PVSCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQG 2740
C + WSG P C+ P C P + I + + F+ N+VV F C G+ M+G
Sbjct: 207 CTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKG 266
Query: 2741 PTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFL 2800
P+ +CQA +W P C V C P +++R + + NF+ G VFY C PGY L
Sbjct: 267 PSHVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQR-DKDNFSPGQEVFYSCEPGYDL 324
Query: 2801 FGSSVLICQPNGQWDKPLPECIMIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSL 2858
GS+ L C P G W P C + C +P VL G+ V + C L
Sbjct: 325 RGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQL 384
Query: 2859 LGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPGTPGHGS-RQESNFRTKSTVRYACD 2914
G S+ C L G W+ S P C +C P P +G ++ S + Y+C
Sbjct: 385 KGSSASYCVLAGMESLWNSSVPVCE---RKSCETPPVPVNGMVHVITDIHVGSRINYSCT 441
Query: 2915 TGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPGTTANGKVFRIDGT-----TFSS 2966
TG+ L G C+ +G+ W+ + P C+ + C NP NG R GT +
Sbjct: 442 TGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNG---RHTGTPLGDIPYGK 498
Query: 2967 SVIYSC-------MEGYILSGPSVRQCT---ANGTWSGTLPNCTI 3001
V Y+C M ++ ++R+ + NG WS P C +
Sbjct: 499 EVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCEL 543
Score = 195 bits (496), Expect = 6e-49
Identities = 147/503 (29%), Positives = 206/503 (40%), Gaps = 50/503 (9%)
Query: 2672 YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSG-NGFNFNDVVTF 2730
Y+C PG+ S+ IC ++ W+ C SC +P P+ G F + +
Sbjct: 63 YECRPGYSGRPFSI-ICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKY 121
Query: 2731 SCNIGYLMQGPTKAQCQANRQ---WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2787
SC GY + G + A C + W + P+C + C P AN S I F YG
Sbjct: 122 SCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTS-ISREYFHYG 180
Query: 2788 TVVFYDCNPG------YFLFGSSVLICQPN----GQWDKPLPECIMID-CGHPGVPPNAV 2836
+VV Y CN G + L G + C G W P P+CI+ + C P V +
Sbjct: 181 SVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 240
Query: 2837 LSGEK--YTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPG 2894
+S + ++ V + C + G S CQ W P CS C P
Sbjct: 241 VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSR----VCQPPPDVL 296
Query: 2895 HGSRQE---SNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGN-PGT 2950
H R + NF V Y+C+ GY L GS C G W+ P C+ C + G
Sbjct: 297 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQ 356
Query: 2951 TANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDP 3007
NG V + V + C EG+ L G S C G W+ ++P C SC P
Sbjct: 357 LPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETP 416
Query: 3008 GIPANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAVT 3063
+P NG+ + D VG ++Y C G+ L G C ++G WS P C+ +
Sbjct: 417 PVPVNGMVHVITDIHVGSRINYSCTTGH--RLIGHSSAECILSGNTAHWSMKPPICQQIF 474
Query: 3064 CPTPPQISNGRLEGT---NFDWGFSISYICSPGYE--LSFPAVLTCV--------GNGTW 3110
CP PP I NGR GT + +G +SY C P + ++F + GNG W
Sbjct: 475 CPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVW 534
Query: 3111 SGEVPQC-LPKFCGDPGIPAQGK 3132
S P+C LP G GK
Sbjct: 535 SSPAPRCELPVGAGSHDALIVGK 557
Score = 179 bits (454), Expect = 4e-44
Identities = 144/499 (28%), Positives = 200/499 (40%), Gaps = 51/499 (10%)
Query: 2722 FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEH 2781
F + + C GY + P C N W+ CK +C +P P N +
Sbjct: 55 FPIGTYLNYECRPGYSGR-PFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKD- 112
Query: 2782 GNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNA--- 2835
+ + + Y C GY L GSS C +G WD P C I CG P N
Sbjct: 113 --IQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFT 170
Query: 2836 VLSGEKYTFGSTVHYSCT----GKR--SLLGQSSRTCQLN----GHWSGSQPHCSGDATG 2885
+S E + +GS V Y C GK+ L+G+ S C G WSG P C
Sbjct: 171 SISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCI--IPN 228
Query: 2886 TCGDPGTPGH--GSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAV 2943
C P S S F V + C G+ + G C A W P C V
Sbjct: 229 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV 288
Query: 2944 QCGNPGTTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3001
C P + + + D FS V YSC GY L G + CT G WS P C +
Sbjct: 289 -CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEV 347
Query: 3002 ISCGD--PGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVM 3056
SC D +P + + + +G V ++C G+ +L GS C + G W+ +
Sbjct: 348 KSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGF--QLKGSSASYCVLAGMESLWNSSV 405
Query: 3057 PTCRAVTCPTPPQISNGRLEG-TNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSG 3112
P C +C TPP NG + T+ G I+Y C+ G+ L + C+ +G WS
Sbjct: 406 PVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSM 465
Query: 3113 EVPQCLPKFCGDPGIPAQGKREGK---SFIYQSEVSFSCN------FPFILVGSST--RI 3161
+ P C FC +P G+ G Y EVS++C+ F L+G ST R
Sbjct: 466 KPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRT 525
Query: 3162 CQ--ADGTWSGSSPHCIEP 3178
+ +G WS +P C P
Sbjct: 526 SEPHGNGVWSSPAPRCELP 544
Score = 168 bits (425), Expect = 1e-40
Identities = 155/545 (28%), Positives = 219/545 (40%), Gaps = 58/545 (10%)
Query: 2465 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2520
C+ PE P + T + + + + C G+ G+ S +C K+S W +
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTSAK 88
Query: 2521 PACQAISCGIPKAPTNG-GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2579
C+ SC P P NG + D +++ Y C GYRL T + S T
Sbjct: 89 DKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWD 147
Query: 2580 NKTPRCVVISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVREC 2630
NKTP C I CG PT NG+ YGS + C+LG F LVG C
Sbjct: 148 NKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYC 207
Query: 2631 LSS----GLWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIGS 2683
S G+WS +C+ + P + NG ++ +N + + V ++C PGF + G
Sbjct: 208 TSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGP 267
Query: 2684 SVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG-RTSGNGFNFN--DVVTFSCNIGYLMQG 2740
S CQ + W +LPSC V C P ++ RT + NF+ V +SC GY ++G
Sbjct: 268 SHVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 326
Query: 2741 PTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFL 2800
T C WS P C+V +C D + N G V + C+ G+ L
Sbjct: 327 STYLHCTPQGDWSPAAPRCEVKSCDD--FLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQL 384
Query: 2801 FGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSG-EKYTFGSTVHYSCTGKR 2856
GSS C G W+ +P C C P VP N ++ GS ++YSCT
Sbjct: 385 KGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGH 444
Query: 2857 SLLGQSSRTCQLNG---HWSGSQPHCSGDATGTCGDPG---TPGHGSRQESNFRTKSTVR 2910
L+G SS C L+G HWS P C C +P H + V
Sbjct: 445 RLIGHSSAECILSGNTAHWSMKPPICQ---QIFCPNPPAILNGRHTGTPLGDIPYGKEVS 501
Query: 2911 YACDT--------GYILHGSEERTC--LANGSWTGRQPECK-AVQCGNPGTTANGKVFRI 2959
Y CD I + RT NG W+ P C+ V G+ GK + +
Sbjct: 502 YTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVGAGSHDALIVGKFYEV 561
Query: 2960 DGTTF 2964
F
Sbjct: 562 FAEEF 566
Score = 160 bits (405), Expect = 2e-38
Identities = 122/398 (30%), Positives = 166/398 (41%), Gaps = 30/398 (7%)
Query: 2927 CLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQC 2986
CL N WT + +CK C NP NG I F S + YSC +GY L G S C
Sbjct: 78 CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC 137
Query: 2987 TANGT---WSGTLPNCTIISCGDPGIPANG--LRYGDDYV-VGQNVSYMCQPG----YTM 3036
+G W P C I CG P ANG +Y G V+Y C G
Sbjct: 138 IISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVF 197
Query: 3037 ELNGSRIRTCTIN----GTWSGVMPTCRAVTCPTPPQISNGRLEGTN---FDWGFSISYI 3089
EL G CT G WSG P C TPP + NG L N F + +
Sbjct: 198 ELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFR 257
Query: 3090 CSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPG---IPAQGKREGKSFIYQSEVSF 3146
C PG+ + P+ + C W E+P C + C P + +R+ +F EV +
Sbjct: 258 CQPGFGMKGPSHVKCQALNKWEPELPSC-SRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 316
Query: 3147 SCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCEN-PGVPRHGSQNNTFGFQVGSV 3205
SC + L GS+ C G WS ++P C SC++ G +G Q+G+
Sbjct: 317 SCEPGYDLRGSTYLHCTPQGDWSPAAPRC---EVKSCDDFLGQLPNGHVLFPLNLQLGAK 373
Query: 3206 VQFHCKKGHLLQGSTTRTCL---PDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHG 3262
V F C +G L+GS+ C+ + W+ P C SC+ P P + V + G
Sbjct: 374 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVG 433
Query: 3263 YTLIYTCQPGFFLAGGTEHRVCRSDNT--WTGKVPICE 3298
+ Y+C G L G + S NT W+ K PIC+
Sbjct: 434 SRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQ 471
Score = 127 bits (319), Expect = 2e-28
Identities = 107/361 (29%), Positives = 142/361 (39%), Gaps = 40/361 (11%)
Query: 2970 YSCMEGYILSG-PSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVS 3027
Y C GY SG P C N W+ C SC +P P NG+ + D +
Sbjct: 63 YECRPGY--SGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIK 120
Query: 3028 YMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGTN---FD 3081
Y C GY L GS TC I+G W P C + C PP I+NG + F
Sbjct: 121 YSCPKGY--RLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFH 178
Query: 3082 WGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQCL-PKFCGDP----G 3126
+G ++Y C+ G +EL + C G WSG PQC+ P C P G
Sbjct: 179 YGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENG 238
Query: 3127 IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENP 3186
I R F V F C F + G S CQA W P C C+ P
Sbjct: 239 ILVSDNRS--LFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC----SRVCQPP 292
Query: 3187 GVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ 3244
H +Q + F G V + C+ G+ L+GST C P WS P C SC
Sbjct: 293 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDD 352
Query: 3245 --PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICEAG 3300
+ P + ++L G + + C GF L G + + ++ W VP+CE
Sbjct: 353 FLGQLPNGHVLFPLNLQL-GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERK 411
Query: 3301 S 3301
S
Sbjct: 412 S 412
Score = 113 bits (283), Expect = 3e-24
Identities = 88/304 (28%), Positives = 125/304 (41%), Gaps = 29/304 (9%)
Query: 3019 DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG- 3077
++ +G ++Y C+PGY+ C N W+ C+ +C PP NG
Sbjct: 54 EFPIGTYLNYECRPGYS---GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVI 110
Query: 3078 TNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCLPKFCGDPGIPAQGKRE 3134
+ + I Y C GY L + TC+ +G W + P C CG P A G
Sbjct: 111 KDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFT 170
Query: 3135 GKS---FIYQSEVSFSCNF------PFILVGSSTRICQAD----GTWSGSSPHCIEPTQT 3181
S F Y S V++ CN F LVG + C + G WSG +P CI P +
Sbjct: 171 SISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNK- 229
Query: 3182 SCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIP 3239
C P V +G +N F + VV+F C+ G ++G + C W P C
Sbjct: 230 -CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC-S 286
Query: 3240 HSCKQPETPAHANVVGMDLP--SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3297
C+ P HA D S G + Y+C+PG+ L G T + C W+ P C
Sbjct: 287 RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGST-YLHCTPQGDWSPAAPRC 345
Query: 3298 EAGS 3301
E S
Sbjct: 346 EVKS 349
Score = 85.9 bits (211), Expect = 7e-16
Identities = 124/506 (24%), Positives = 183/506 (36%), Gaps = 96/506 (18%)
Query: 2118 QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPLPRC 2175
+SC +P NG + D I + C GY LIG+S+ TC+ G + W++ P C
Sbjct: 94 KSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Query: 2176 EAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY---- 2230
+ + CG T NG S EY ++ G + F ++ IY
Sbjct: 154 DRIICGLPPTIANGDFTS--ISREYFHYGSVVTYHCNLGSRGKKV-FELVGEPSIYCTSK 210
Query: 2231 -DFITVWDGPDQNS--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVL 2281
D + +W GP P + + S++S + + + F G +
Sbjct: 211 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHV 270
Query: 2282 SYHAYQL---------RVCQPPPPVPNAEILTED-DEFEIGDIIRYQCLPGFTLVGNAIL 2331
A RVCQPPP V +AE D D F G + Y C PG+ L G+ L
Sbjct: 271 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYL 330
Query: 2332 TCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCA-WSISVEKGY 2390
C + A P C+V + L G +L P NLQ+ A ++G+
Sbjct: 331 HCT--PQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP------LNLQLGAKVDFVCDEGF 382
Query: 2391 NITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHG 2450
+ G + VL + ++S+ +
Sbjct: 383 QL-------------------KGSSASYCVLAGMESLWNSSVPVCERKS----------- 412
Query: 2451 NNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSS 2510
C TP P +G + T + S + ++C G RL+G SSA C S
Sbjct: 413 --------------CETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSG 458
Query: 2511 YGYHAWDAPVPACQAISCGIPKAPTNG---GILTTDYLVGTRVTYFCND------GYRL- 2560
H W P CQ I C P A NG G D G V+Y C+ + L
Sbjct: 459 NTAH-WSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLI 517
Query: 2561 -SSKELTTAVCQSDGTWSNHNKTPRC 2585
S T+ +G WS + PRC
Sbjct: 518 GESTIRRTSEPHGNGVWS--SPAPRC 541
Score = 67.4 bits (163), Expect = 2e-10
Identities = 97/432 (22%), Positives = 157/432 (36%), Gaps = 76/432 (17%)
Query: 1594 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
R+SC +P + +NG + D + S + Y C GY L G S+ TCI+ + W+ P
Sbjct: 93 RKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGN-TVIWDNKTP 151
Query: 1653 SC-HAPCGSRSTGSEG--TVLSPNYPKNYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH 1708
C CG T + G T +S Y SV ++C K F + G+ + TS
Sbjct: 152 VCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKD 211
Query: 1709 DVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKG-FHFV 1762
D V ++ GP Q + + + + + +S + + F KG H
Sbjct: 212 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVK 271
Query: 1763 YQAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIR 1813
QA+ + CS V +P +R + F+ G V + C PGY L GS +
Sbjct: 272 CQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLH 331
Query: 1814 CETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAG 1872
C W+ + P C + C L G + + P + L EG
Sbjct: 332 C----TPQGDWSPAAPRCEVKSCDDFL----GQLPNGHVLFPLNLQLGAKVDFVCDEGFQ 383
Query: 1873 IQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS 1932
++ S+ +SL +++ P S T P +N + +
Sbjct: 384 LKGSSASYCVLAGMESL-----WNSSVPVCERKSCETPPVPVNGMVHVI----------- 427
Query: 1933 AAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC-MPG 1991
+ I +G R +++ C G+ L GHS C + G
Sbjct: 428 -----------------------TDIHVGSR------INYSCTTGHRLIGHSSAECILSG 458
Query: 1992 PVRRWNYPIPIC 2003
W+ PIC
Sbjct: 459 NTAHWSMKPPIC 470
Score = 62.4 bits (150), Expect = 8e-09
Identities = 82/304 (26%), Positives = 126/304 (41%), Gaps = 43/304 (14%)
Query: 171 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
++ + SC NP P G+ + + +I+YSC GY L G TCI S NT WD
Sbjct: 89 DKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWD 147
Query: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPN-------EYHNNADCTWTIVAEPGDTISLI 282
P+C CG ++G +S S YH N V E S+
Sbjct: 148 NKTPVC-DRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIY 206
Query: 283 FTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
T K D + I P + PP + +N + V+D+ + +
Sbjct: 207 CT-----SKDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLF 248
Query: 343 QVKKAIDFKSR-GFKLFPGKDNSN-KFSILN--EGGIKTASNLC---PDPGEPENGKRIG 395
+ + ++F+ + GF + K S+ K LN E + + S +C PD E +R
Sbjct: 249 SLNEVVEFRCQPGFGM---KGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDK 305
Query: 396 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGT 454
+FS G V +SC+ Y L+G+ + C + WS P C+VK+C L Q P+G
Sbjct: 306 DNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGD----WSPAAPRCEVKSCDDFLGQLPNGH 361
Query: 455 FTSP 458
P
Sbjct: 362 VLFP 365
Score = 58.2 bits (139), Expect = 1e-07
Identities = 107/470 (22%), Positives = 157/470 (33%), Gaps = 101/470 (21%)
Query: 705 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINARRFG-DNFQLGSSIS 753
L ++ SGR F+I + C +P P+N + Q S I
Sbjct: 61 LNYECRPGYSGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIK 120
Query: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC-----GAP---CGGHFSAPSGVILSP 805
C +G+ + G+ + TCI+ V+W P C G P G F++ S
Sbjct: 121 YSCPKGY-RLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHY 179
Query: 806 GWPGYYKDSLNCEW--VIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNG 863
G Y +L V E SI T + Q + PN +P NG
Sbjct: 180 GSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPP-NVENG 238
Query: 864 TQVPQFLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 910
L S + ++ L R GF + H + +N + C P
Sbjct: 239 -----ILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPP 293
Query: 911 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 967
+H R D FS G V +SC+ GY L L C WS P C+ D
Sbjct: 294 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDF 353
Query: 968 RG--PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1025
G P+G +L +P +L VD +G Q
Sbjct: 354 LGQLPNGHVL-------FPLNLQLGAKVDFVCDEGFQ----------------------- 383
Query: 1026 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1085
L GS + AG+ +N + + CE P +P
Sbjct: 384 ------LKGSSASYCVLAGMESL-----------------WNSSVPVCERKSCETPPVPV 420
Query: 1086 YGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC 1133
G + + +G + +SC++G+RL G S C L G WS P C
Sbjct: 421 NGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Score = 57.0 bits (136), Expect = 3e-07
Identities = 102/442 (23%), Positives = 157/442 (35%), Gaps = 59/442 (13%)
Query: 1271 STIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSCIAECGGRFKGESSGRILSP---- 1325
S I Y C GY L GSS C+ +G WD P C G ++G S
Sbjct: 117 SQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREY 176
Query: 1326 ---GYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEIS 1382
G Y NL + S+ + D D + +W GP ++ + +
Sbjct: 177 FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKD-----DQVGIWSGPAPQCIIPNKCT 231
Query: 1383 GSLIPEGIHSTLN--IVTIQFDTDFYISKSGFAIQFSSSV---------------ATACR 1425
+ GI + N + ++ +F + GF ++ S V + C+
Sbjct: 232 PPNVENGILVSDNRSLFSLNEVVEFRC-QPGFGMKGPSHVKCQALNKWEPELPSCSRVCQ 290
Query: 1426 DPGVPMNGTR---NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1482
P ++ R + D PG V + C+PGY+L+G + C + W P+ P C
Sbjct: 291 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGD---WSPAAPRCEV 347
Query: 1483 PCGGNLTGS--SGFILSP-NFPHPYPHSRDCDWTITV---NADYVISLAFISF--SIEPN 1534
+ G +G +L P N CD + +A Y + S S P
Sbjct: 348 KSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV 407
Query: 1535 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMH-LAFRSDGSVSYTG--FHLEYKA 1591
+ P + ++ D + RI S T H L S +G H K
Sbjct: 408 CERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKP 467
Query: 1592 KLRES--CFDPGNIMNGTRLGM---DYKLGSTVTYYCD------AGYVLQGYSTLTCIMG 1640
+ + C +P I+NG G D G V+Y CD + L G ST+
Sbjct: 468 PICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSE 527
Query: 1641 DDGRPGWNRALPSCHAPCGSRS 1662
G W+ P C P G+ S
Sbjct: 528 PHGNGVWSSPAPRCELPVGAGS 549
Score = 53.1 bits (126), Expect = 5e-06
Identities = 106/477 (22%), Positives = 159/477 (33%), Gaps = 60/477 (12%)
Query: 366 KFSILNEGGIKTASNLCPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQR 424
K S+ K C +P +P NG + D S +++SC + Y L G+ S TC
Sbjct: 80 KNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC-I 138
Query: 425 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 484
I+ W + PVC CG +G FTS + + + + KV +
Sbjct: 139 ISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFE 198
Query: 485 INFE-EFDLEIGYDTLTIGDGGE----VGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQT 539
+ E D + I G + + T V G V D S + +
Sbjct: 199 LVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 258
Query: 540 DESVGSVG------FKVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFEC 586
G G +N E E SC P + R+ D FS + + C
Sbjct: 259 QPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSC 318
Query: 587 QFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSPDYPEGYGNNLNCI 644
+ G++L G + C WS P C +F P G VL P L
Sbjct: 319 EPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP-----LNLQLGAK 373
Query: 645 WTIISDPGSRIHLSFNDFDL--------ESQFDFLAVKDGDSPESPILG---TFTGAEVP 693
+ D G ++ S + + S K ++P P+ G T V
Sbjct: 374 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVG 433
Query: 694 SHLT---SNSHILRLEFQADHSMSGRGFN------ITYNTFGHNECPDPGIPINARRFG- 743
S + + H L A+ +SG + I F CP+P +N R G
Sbjct: 434 SRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIF----CPNPPAILNGRHTGT 489
Query: 744 --DNFQLGSSISVICEEG-----FIKTQGTETI-TCILMDGKVMWSGLIPKCGAPCG 792
+ G +S C+ G TI G +WS P+C P G
Sbjct: 490 PLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVG 546
Score = 52.8 bits (125), Expect = 6e-06
Identities = 28/64 (43%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 174 QSSSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 232
+ SC P VP G+++ T VG +I YSC TG+ L GH CI S NTA W
Sbjct: 409 ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSMKP 467
Query: 233 PICR 236
PIC+
Sbjct: 468 PICQ 471
Score = 46.6 bits (109), Expect = 4e-04
Identities = 95/434 (21%), Positives = 144/434 (33%), Gaps = 90/434 (20%)
Query: 905 SCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPLPTCD 960
SC +P PV+G + D S + +SC GYRL C W + P CD
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 961 AL-CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1019
+ CG +G S F+ S+ + GK V F L
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKV------FELVGEPSIYCT 208
Query: 1020 TENG-----SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE---GFNITFS 1071
+++ S P + PP + G+ + L +++ + + GF +
Sbjct: 209 SKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV-VEFRCQPGFGMKGP 267
Query: 1072 EY-------NLEP--------CEDPGIPQYGSRIGF---NFGIGDTLTFSCSSGYRLEGT 1113
+ EP C+ P + R NF G + +SC GY L G+
Sbjct: 268 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 1114 SEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGK 1173
+ + C G WS PRC + S + L N ++ + +Q G
Sbjct: 328 TYLHCTPQGD--WSPAAPRCEVK-------------SCDDFLGQLPNGHVLFPLNLQLGA 372
Query: 1174 GINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEG 1233
++ F +G LK G+S L+ + LW NS
Sbjct: 373 KVD-----FVCDEGFQLK----------------GSSASYCVLAGMES-LW---NSSVPV 407
Query: 1234 TDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKC-M 1292
E CE P +P G GS I Y C G+ L G S +C +
Sbjct: 408 C-----------ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECIL 456
Query: 1293 TGERRAWDYPLPSC 1306
+G W P C
Sbjct: 457 SGNTAHWSMKPPIC 470
Score = 40.8 bits (94), Expect = 0.024
Identities = 104/467 (22%), Positives = 167/467 (35%), Gaps = 76/467 (16%)
Query: 1774 CSSVPEPRFGR-RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1832
C + P+P G + + S + + C GY L GS + C N++ W++ P C
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVI-WDNKTPVCD 154
Query: 1833 -VPCG-------GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEH 1884
+ CG G T G Y NL K V E G + + T
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGK-KVFELVG---EPSIYCTSK 210
Query: 1885 NWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNST---------SNNLYLNFQSDISVSAAG 1935
+ D + + G AP+ + T P++ N S N + F+ G
Sbjct: 211 D-DQVGIWSGP---APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKG 266
Query: 1936 -FHLEYTAIG-----LDSCPEPQTPSSGI-------KIGDRYMVGDVVSFQCDQGYSLQG 1982
H++ A+ L SC P + + D + G V + C+ GY L+G
Sbjct: 267 PSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 326
Query: 1983 HSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIG 2042
+++ C P W+ P C + + DF G + P +P +L ++
Sbjct: 327 STYLHCTPQG--DWSPAAPRCEVK---SCDDFLGQL--PNGHVLFPLNLQLGAKVDFVCD 379
Query: 2043 FGVHLQFVNFSTETIHDYLEVRSGS--------SETSTV-----IGRLSGPQIPSSL-FS 2088
G L+ + S + + + S ET V + ++ + S + +S
Sbjct: 380 EGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYS 439
Query: 2089 TTHETSLYFHSD----YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGN---DFTVGQT 2141
T L HS S N + + Q CP+P NG G D G+
Sbjct: 440 CTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKE 499
Query: 2142 ISFECFPG------YTLIGNSALTCLHGVSRN--WNHPLPRCEALCG 2180
+S+ C P + LIG S + N W+ P PRCE G
Sbjct: 500 VSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVG 546
Score = 40.4 bits (93), Expect = 0.031
Identities = 63/274 (22%), Positives = 101/274 (36%), Gaps = 30/274 (10%)
Query: 1078 CEDPGIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRCVA 1135
C +P P G + + + + +SC GYRL G+S C+ G V W P C
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDR 155
Query: 1136 E-CGASAT--NNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVL 1190
CG T N + +S Y +Y + + C + + + + ++ D +
Sbjct: 156 IICGLPPTIANGDFTSISREY-FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQV 214
Query: 1191 KIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTE-GTDEGFQLVYTSF---- 1245
I+ G + T ++ L S + L+ N E GF + S
Sbjct: 215 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLF-SLNEVVEFRCQPGFGMKGPSHVKCQ 273
Query: 1246 -------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCM 1292
EL C P + D+ +F+ G + Y C PGY L GS+ L C
Sbjct: 274 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCT 333
Query: 1293 TGERRAWDYPLPSCIAECGGRFKGE-SSGRILSP 1325
+ W P C + F G+ +G +L P
Sbjct: 334 --PQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP 365
Score = 37.7 bits (86), Expect = 0.20
Identities = 67/302 (22%), Positives = 102/302 (33%), Gaps = 53/302 (17%)
Query: 728 NECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 784
N+C P + N DN F L + C+ GF +G + C ++ W +
Sbjct: 228 NKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGF-GMKGPSHVKCQALN---KWEPEL 282
Query: 785 PKCGAPCGGHFSAPSGVI-----------LSPGWPGYYKDS----LNCEWVIEAEPGHSI 829
P C C P V+ SPG +Y L + P
Sbjct: 283 PSCSRVC----QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDW 338
Query: 830 KITFERFQTELNYDVLEVHDGPNLLSPL---LGSYNGTQVPQ-FLFSSSNFIYLLFTTDN 885
R + + D L ++L PL LG+ + F S+ Y +
Sbjct: 339 SPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 398
Query: 886 SRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRL---SHE 941
S N+ + SC P +PV+G + D +GS +++SC +G+RL S
Sbjct: 399 SLWNSSVPV------CERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSA 452
Query: 942 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
E +L WS P C I P P T D+ +GK V
Sbjct: 453 ECILSGNTAHWSMKPPICQ------------QIFCPNPPAILNGRHTGTPLGDIPYGKEV 500
Query: 1002 QF 1003
+
Sbjct: 501 SY 502
Score = 37.0 bits (84), Expect = 0.35
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 1423 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
+CR+P P+NG + + + + C GY L G TCI N W PVC
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Score = 35.0 bits (79), Expect = 1.3
Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 20/122 (16%)
Query: 324 RLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCP 383
++ FV D + +G SA Y V ++ S+ N C
Sbjct: 373 KVDFVCDEGFQLKGSSASYCVLAGME------------------SLWNSSVPVCERKSCE 414
Query: 384 DPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVK 442
P P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 415 TPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAEC-ILSGNTAHWSMKPPICQQI 473
Query: 443 TC 444
C
Sbjct: 474 FC 475
Score = 33.9 bits (76), Expect = 2.9
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 2116 QLQSCPD-PRPFRNGFVIGN-DFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPL 2172
+++SC D NG V+ + +G + F C G+ L G+SA C L G+ WN +
Sbjct: 346 EVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 405
Query: 2173 PRCE-ALCGGNITAMNGTIY 2191
P CE C +NG ++
Sbjct: 406 PVCERKSCETPPVPVNGMVH 425
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 196 bits (499), Expect = 3e-49
Identities = 151/507 (29%), Positives = 223/507 (43%), Gaps = 51/507 (10%)
Query: 2527 SCGIPK-----APTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
+CG P AP + + T + GT + Y C GY + S T C SDG W +
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGY-VRSHSTQTLTCNSDGEWVYNT- 106
Query: 2582 TPRCVVISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVREC--LSSGL-WS 2637
C+ C NG +I T S+GS F+C GF L+GS C G+ WS
Sbjct: 107 --FCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWS 164
Query: 2638 ESETRCLAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHN-- 2693
+C C P I NG+ GE Y Y +V Y C+P F L+G + C ++
Sbjct: 165 HPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI 224
Query: 2694 --WSGQLPSCVPVSCGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQAN 2749
W P+C ++C P SG G +N+ D + F C G++++G + C A+
Sbjct: 225 GVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDAD 284
Query: 2750 RQWSHPPPMCKVVNCSD-PGIPANS--KRESKIEHGNFTYGTVVFYDCNPGY--FLFGSS 2804
+W+ PP C+ +C + P IP S + + GTV+ Y C+PGY +
Sbjct: 285 SKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPT 344
Query: 2805 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK--------YTFGSTVHYSCTGKR 2856
+ICQ N +W P C + C P + + K Y +G + +SC
Sbjct: 345 TVICQKNLRW-TPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSC---- 399
Query: 2857 SLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT--KSTVRYACD 2914
+ S CQ +G WS P C GD C P HG ++S+ + K + Y CD
Sbjct: 400 HETSRFSAICQGDGTWSPRTPSC-GD---ICNFPPKIAHGHYKQSSSYSFFKEEIIYECD 455
Query: 2915 TGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF--SSSVIYSC 2972
GYIL G + +C + W+ P+CKA+ C P NG++ +D + +V C
Sbjct: 456 KGYILVGQAKLSC-SYSHWSAPAPQCKAL-CRKP-ELVNGRL-SVDKDQYVEPENVTIQC 511
Query: 2973 MEGYILSGPSVRQCTANGTWSGTLPNC 2999
GY + GP C+ N TW +P C
Sbjct: 512 DSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 161 bits (408), Expect = 9e-39
Identities = 140/518 (27%), Positives = 221/518 (42%), Gaps = 54/518 (10%)
Query: 2763 NCSDPG-IPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSS-VLICQPNGQWDKPLPE 2820
NC P + + + + F GT + Y C PGY S+ L C +G+W
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-F 107
Query: 2821 CIMIDCGHPGVPPNAVLSGEK-YTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQ 2876
CI C HPG N + + +FGS + +SC+ L+G ++ C++ WS
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 2877 PHCSGDATGTCGDPGTPGHG--SRQESNFRTKSTVRYACDTGYILHGSEERTCLAN---- 2930
P C C P +G S +E+ + +V Y+CD + L G +C
Sbjct: 168 PQCE---IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI 224
Query: 2931 GSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTA 2988
G W P C+ + C P + +G++ G ++ ++++ C +G++L G SV C A
Sbjct: 225 GVWRPSPPTCEKITCRKPDVS-HGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDA 283
Query: 2989 NGTWSGTLPNCTIISCGD-PGIP-ANGLRY-----GDDYVVGQNVSYMCQPGYTMELNGS 3041
+ W+ + P C SC + P IP A+ Y D YVVG + Y C PGY +
Sbjct: 284 DSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEP 343
Query: 3042 RIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTN---------FDWGFSISYICSP 3092
C N W+ C A+ CP P+++NG + + +G IS+ C
Sbjct: 344 TTVICQKNLRWTPYQ-GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSC-- 399
Query: 3093 GYELS-FPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG--KREGKSFIYQSEVSFSCN 3149
+E S F A+ C G+GTWS P C C P A G K+ ++ E+ + C+
Sbjct: 400 -HETSRFSAI--CQGDGTWSPRTPSC-GDICNFPPKIAHGHYKQSSSYSFFKEEIIYECD 455
Query: 3150 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3209
+ILVG + C + WS +P C + C P + + + V
Sbjct: 456 KGYILVGQAKLSC-SYSHWSAPAPQC----KALCRKPELVNGRLSVDKDQYVEPENVTIQ 510
Query: 3210 CKKGHLLQGSTTRTCLPDLTWSGIQPEC---IPHSCKQ 3244
C G+ + G + TC + TW P+C P C+Q
Sbjct: 511 CDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQ 548
Score = 159 bits (403), Expect = 4e-38
Identities = 119/439 (27%), Positives = 185/439 (42%), Gaps = 37/439 (8%)
Query: 2528 CGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCV 2586
C P NG + + TD G+++ + C++G+ L + Q G +H P+C
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSH-PLPQCE 171
Query: 2587 VISCGELPTPPNGNKIGTQT--SYGSTAIFTCDLGFMLVGSAVRECL----SSGLWSESE 2640
++ C P NG G + +YG + ++CD F L+G A C + G+W S
Sbjct: 172 IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSP 231
Query: 2641 TRCLAGHCGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQ 2697
C C P+ + +G+++ G Y Y+DT+V++C GF L GSSV C D W+
Sbjct: 232 PTCEKITCRKPD-VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPS 290
Query: 2698 LPSCVPVSC------GHPGSPIYGR-TSGNGFNFNDVVTFSCNIGY--LMQGPTKAQCQA 2748
P+C P SC H Y R T + + V+ + C+ GY PT CQ
Sbjct: 291 PPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQK 350
Query: 2749 NRQWSHPPPMCKVVNCSDP----GIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSS 2804
N +W+ P C+ + C +P G ++ H + YG + + C+
Sbjct: 351 NLRWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRF 405
Query: 2805 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYT-FGSTVHYSCTGKRSLLGQSS 2863
ICQ +G W P C I P + Y+ F + Y C L+GQ+
Sbjct: 406 SAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAK 465
Query: 2864 RTCQLNGHWSGSQPHCSGDATGTCGDPG-TPGHGSRQESNFRTKSTVRYACDTGYILHGS 2922
+C + HWS P C C P G S + + V CD+GY + G
Sbjct: 466 LSCSYS-HWSAPAPQCK----ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGP 520
Query: 2923 EERTCLANGSWTGRQPECK 2941
+ TC N +W P+C+
Sbjct: 521 QSITCSGNRTWYPEVPKCE 539
Score = 156 bits (395), Expect = 3e-37
Identities = 142/521 (27%), Positives = 216/521 (41%), Gaps = 45/521 (8%)
Query: 2586 VVISCGELPT-----PPNGNKIGTQTSYGSTAIFTCDLGFMLVGSA-VRECLSSGLWSES 2639
V+ +CG PT P + T+ G+T +TC G++ S C S G W +
Sbjct: 46 VLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYN 105
Query: 2640 ETRCLAGHCGIPELIVNGQV-IGENYGYRDTVVYQCNPGFRLIGSSVRICQ-QDHN--WS 2695
T C+ C P + NGQV I + + + + C+ GF LIGS+ C+ QD WS
Sbjct: 106 -TFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWS 164
Query: 2696 GQLPSCVPVSCGHPGSPIYGRTSG--NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ-- 2751
LP C V C P GR SG N + + VT+SC+ + + G C +
Sbjct: 165 HPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI 224
Query: 2752 --WSHPPPMCKVVNCSDPGIPANSKRESKIEHGN-FTYGTVVFYDCNPGYFLFGSSVLIC 2808
W PP C+ + C P + S E G + Y + + C G+ L GSSV+ C
Sbjct: 225 GVWRPSPPTCEKITCRKPDV---SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC 281
Query: 2809 QPNGQWDKPLPECIMIDCGH-PGVPPNA------VLSGEKYTFGSTVHYSC-TGKRSLLG 2860
+ +W+ P C C + P +P + + Y G+ + Y C G +
Sbjct: 282 DADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTD 341
Query: 2861 QSSRT-CQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKS--TVRYACDTGY 2917
+ + CQ N W+ Q G C +P Q R + Y + +
Sbjct: 342 EPTTVICQKNLRWTPYQ----GCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISF 397
Query: 2918 ILHGSEERT--CLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF-SSSVIYSCME 2974
H + + C +G+W+ R P C + C P A+G + +F +IY C +
Sbjct: 398 SCHETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDK 456
Query: 2975 GYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPG 3033
GYIL G + C+ + WS P C + C P + L D YV +NV+ C G
Sbjct: 457 GYILVGQAKLSCSYSH-WSAPAPQCKAL-CRKPELVNGRLSVDKDQYVEPENVTIQCDSG 514
Query: 3034 YTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGR 3074
Y + G + TC+ N TW +P C T Q+ G+
Sbjct: 515 YGVV--GPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGK 553
Score = 144 bits (362), Expect = 2e-33
Identities = 130/512 (25%), Positives = 209/512 (40%), Gaps = 53/512 (10%)
Query: 2822 IMIDCGHP-----GVPPNAVLSGEKYTFGSTVHYSCT-GKRSLLGQSSRTCQLNGHWSGS 2875
++ +CG P P + L+ ++ G+T+ Y+C G + TC +G W +
Sbjct: 46 VLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYN 105
Query: 2876 QPHCSGDATGTCGDPGTPGHGSRQ-ESNFRTKSTVRYACDTGYILHGSEERTCLANG--- 2931
C C PG +G + +++ S + ++C G+ L GS C
Sbjct: 106 T-FC---IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV 161
Query: 2932 SWTGRQPECKAVQCGNPGTTANGKVFRIDGT-TFSSSVIYSCMEGYILSGPSVRQCTAN- 2989
W+ P+C+ V+C P NG+ + + SV YSC + L G + CT
Sbjct: 162 GWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVEN 221
Query: 2990 ---GTWSGTLPNCTIISCGDPGIPANGL--RYGDDYVVGQNVSYMCQPGYTMELNGSRIR 3044
G W + P C I+C P + + +G Y + + CQ G+ L GS +
Sbjct: 222 ETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFV--LRGSSVI 279
Query: 3045 TCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG----TNFDW---GFSISYICSPGYELS 3097
C + W+ P C +C P I + E T D G + Y C PGY+ +
Sbjct: 280 HCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPT 339
Query: 3098 F--PAVLTCVGNGTWS---GEVPQCLPKFCGDPGIPAQGKREGKS----FIYQSEVSFSC 3148
P + C N W+ G C P+ + G Q ++ + + Y E+SFSC
Sbjct: 340 TDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSC 399
Query: 3149 NFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFGFQVGSVV 3206
+ + ICQ DGTWS +P C + C P HG Q++++ F ++
Sbjct: 400 HE----TSRFSAICQGDGTWSPRTPSCGD----ICNFPPKIAHGHYKQSSSYSFFKEEII 451
Query: 3207 QFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLI 3266
+ C KG++L G +C WS P+C C++PE V D +
Sbjct: 452 -YECDKGYILVGQAKLSCSYS-HWSAPAPQC-KALCRKPELVNGRLSVDKDQYVEPENVT 508
Query: 3267 YTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3298
C G+ + G + C + TW +VP CE
Sbjct: 509 IQCDSGYGVVG-PQSITCSGNRTWYPEVPKCE 539
Score = 128 bits (321), Expect = 1e-28
Identities = 114/456 (25%), Positives = 180/456 (39%), Gaps = 55/456 (12%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
C P +G + +T S + ++C GF L+G +++ C G W P+P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV-GWSHPLPQCE 171
Query: 2525 AISCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSD--GTWSNHN 2580
+ C P NG + Y G VTY C+ + L + +++ G W
Sbjct: 172 IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW--RP 229
Query: 2581 KTPRCVVISCGELPTPPNGNKI---GTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWS 2637
P C I+C + P +G + G +Y T +F C GF+L GS+V C + W+
Sbjct: 230 SPPTCEKITCRK-PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWN 288
Query: 2638 ESETRCLAGHC-GIPEL------IVNGQVIGENYGYRDTVVYQCNPGFRLIGS--SVRIC 2688
S C C +P++ + Y + Y+C+PG++ + IC
Sbjct: 289 PSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVIC 348
Query: 2689 QQDHNWSGQLPSCVPVSCGHP----GSPIYGRTSGNG----FNFNDVVTFSCNIGYLMQG 2740
Q++ W+ C + C P G R S + + D ++FSC+
Sbjct: 349 QKNLRWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCH----ETS 403
Query: 2741 PTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT-------YGTVVFYD 2793
A CQ + WS P C + C+ P KI HG++ + + Y+
Sbjct: 404 RFSAICQGDGTWSPRTPSCGDI-CNFP---------PKIAHGHYKQSSSYSFFKEEIIYE 453
Query: 2794 CNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK--YTFGSTVHYS 2851
C+ GY L G + L C W P P+C + C P + N LS +K Y V
Sbjct: 454 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPEL-VNGRLSVDKDQYVEPENVTIQ 510
Query: 2852 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTC 2887
C ++G S TC N W P C + C
Sbjct: 511 CDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGC 546
Score = 98.2 bits (243), Expect = 1e-19
Identities = 77/261 (29%), Positives = 113/261 (43%), Gaps = 23/261 (8%)
Query: 3064 CPTPPQISNGR-----LEGTNFDWGFSISYICSPGYELSFPA-VLTCVGNGTWSGEVPQC 3117
C PP +S L T F G ++ Y C PGY S LTC +G W C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FC 108
Query: 3118 LPKFCGDPGIPAQGKREGKSFI-YQSEVSFSCNFPFILVGSSTRICQADGT---WSGSSP 3173
+ K C PG G+ E K+ + + S++ FSC+ F L+GS+T C+ WS P
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 3174 HCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDL---- 3228
C C+ P R+G + F G V + C L G + +C +
Sbjct: 169 QC---EIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIG 225
Query: 3229 TWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGY--TLIYTCQPGFFLAGGTEHRVCRS 3286
W P C +C++P+ +H +V P + Y T+++ CQ GF L G + C +
Sbjct: 226 VWRPSPPTCEKITCRKPDV-SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIH-CDA 283
Query: 3287 DNTWTGKVPICEAGSKILVKD 3307
D+ W P CE S I + D
Sbjct: 284 DSKWNPSPPACEPNSCINLPD 304
Score = 56.2 bits (134), Expect = 6e-07
Identities = 60/241 (24%), Positives = 95/241 (39%), Gaps = 35/241 (14%)
Query: 2111 VYQAYQL-QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRN 2167
VY + + + C P RNG V I D + G I F C G+ LIG++ C +
Sbjct: 103 VYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG 162
Query: 2168 WNHPLPRCEAL-CGGNITAMNG------TIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN 2220
W+HPLP+CE + C NG Y+ G+ Y + F L+ + N
Sbjct: 163 WSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTY-SCDPRFSLLGHASISCTVEN 221
Query: 2221 FTV---LQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSG 2277
T+ + P + IT P + + +Y+ + I+ K F G
Sbjct: 222 ETIGVWRPSPPTCEKITC------RKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRG 275
Query: 2278 FFVLSYHAYQLRVCQPPPPVPNAEI---------------LTEDDEFEIGDIIRYQCLPG 2322
V+ A PP PN+ I T++D + +G ++RY+C PG
Sbjct: 276 SSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPG 335
Query: 2323 F 2323
+
Sbjct: 336 Y 336
Score = 50.4 bits (119), Expect = 3e-05
Identities = 112/479 (23%), Positives = 168/479 (35%), Gaps = 108/479 (22%)
Query: 1241 VYTSFEL-SHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERR-A 1298
VY +F + C PG + G GS I + C+ G+ L GS+ +C +R
Sbjct: 103 VYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG 162
Query: 1299 WDYPLPSC-IAEC-------GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVS 1350
W +PLP C I +C GR GE + Y + + C DP
Sbjct: 163 WSHPLPQCEIVKCKPPPDIRNGRHSGEEN------FYAYGFSVTYSC------DP-RFSL 209
Query: 1351 LQFLAFDTEASHDILRVW-DGPPENDMLL---KEISGSLIPEGIHSTLNIVTIQFDTDFY 1406
L + ++ + VW PP + + ++S + G N DT +
Sbjct: 210 LGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYK----DTIVF 265
Query: 1407 ISKSGFAIQFSSSV-----------ATACRD------PGVPMNG------TRNGDGREPG 1443
+ GF ++ SS + AC P +P D G
Sbjct: 266 KCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVG 325
Query: 1444 DTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHP 1503
+ ++C PGY+ +E T I +N W P C A C ++G I
Sbjct: 326 TVLRYRCHPGYKPTTDEPTTVICQKN-LRWTPYQG-CEALCCPEPKLNNGEITQ------ 377
Query: 1504 YPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQD-SKLPER 1562
+ SR + + D ISFS F I G + SP S D P +
Sbjct: 378 HRKSRPANHCVYFYGDE------ISFSCHETSRFSAICQGDGTWSPRTPSCGDICNFPPK 431
Query: 1563 IESSSNTMHLAFRSDGSVSY----------TGFHLEYKAKL--------------RESCF 1598
I H ++ S S+ G+ L +AKL + C
Sbjct: 432 I------AHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCR 485
Query: 1599 DPGNIMNGTRLGMD---YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
P ++NG RL +D Y VT CD+GY + G ++TC G W +P C
Sbjct: 486 KP-ELVNG-RLSVDKDQYVEPENVTIQCDSGYGVVGPQSITC----SGNRTWYPEVPKC 538
Score = 49.7 bits (117), Expect = 5e-05
Identities = 96/440 (21%), Positives = 155/440 (35%), Gaps = 71/440 (16%)
Query: 1613 YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNR--ALPSCHAPCGSRSTGSEGTVL 1670
+K G+T+ Y C GYV + +ST T DG +N C P R+ E
Sbjct: 71 FKTGTTLKYTCLPGYV-RSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVE---- 125
Query: 1671 SPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSL--- 1727
+ S G +S + + F + G + + D + P Q ++
Sbjct: 126 ---IKTDLSFGSQIEFSCS--EGFFLIGSTTS-RCEVQDRGVGWSHPLPQCEIVKCKPPP 179
Query: 1728 ---SGSHSGESLPLSSGNQITI----RFTSVG----PITAKGFHF-VYQAVPRTSSTQCS 1775
+G HSGE + G +T RF+ +G T + V++ P T
Sbjct: 180 DIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC 239
Query: 1776 SVPEPRFGRRI---GNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1832
P+ G + G + +++F C G++L GS I C+ + ++WN S P C
Sbjct: 240 RKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCD----ADSKWNPSPPAC- 294
Query: 1833 VPCGGILTKRKGTILSPGYPEPYDNNLNCV-----------WKITVPEGAGIQVQVVSFA 1881
P I YP P ++ V +K T E + Q
Sbjct: 295 EPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQ----- 349
Query: 1882 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 1941
W + P+L +G H + +N+ + +IS S
Sbjct: 350 KNLRWTPYQGCEALCCPEPKLN--NGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSA 407
Query: 1942 AIGLDSCPEPQTPSSG-------------IKIGDRY-MVGDVVSFQCDQGYSLQGHSHIT 1987
D P+TPS G K Y + + ++CD+GY L G + ++
Sbjct: 408 ICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLS 467
Query: 1988 CMPGPVRRWNYPIPICLAQC 2007
C W+ P P C A C
Sbjct: 468 C---SYSHWSAPAPQCKALC 484
Score = 47.0 bits (110), Expect = 3e-04
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
C PGE NG+ I +D S GS ++FSC E + L G+ + C+ + + WS P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCE-VQDRGVGWSHPLPQCE 171
Query: 441 VKTC 444
+ C
Sbjct: 172 IVKC 175
Score = 44.7 bits (104), Expect = 0.002
Identities = 46/232 (19%), Positives = 94/232 (40%), Gaps = 35/232 (15%)
Query: 922 FSIGSTVSFSCDSGYRLSHEEP--LLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGY 979
+ +G+ + + C GY+ + +EP ++C+KN W+ P C+ALC + + +G I +
Sbjct: 322 YVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQ--H 378
Query: 980 PEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGS--DL 1037
+ P + +C + +G + F+ H + + I + P G +
Sbjct: 379 RKSRPAN-HCVY----FYGDEISFSCH-----ETSRFSAICQGDGTWSPRTPSCGDICNF 428
Query: 1038 PPTINAG------LYGNFRAQLRFISD---FSISYEGFNITFSEYNLEPCEDPGIPQYGS 1088
PP I G Y F+ ++ + D + + ++S ++ + + +
Sbjct: 429 PPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPE 488
Query: 1089 RIGFNFGIG-------DTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
+ + + +T C SGY + G I C G R W +P+C
Sbjct: 489 LVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITC--SGNRTWYPEVPKC 538
Score = 43.1 bits (100), Expect = 0.005
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 382 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
C P + NG+ G + ++ G +V +SCD + L G SI+C E W P C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 440 KVKTC 444
+ TC
Sbjct: 235 EKITC 239
Score = 42.7 bits (99), Expect = 0.006
Identities = 74/333 (22%), Positives = 114/333 (34%), Gaps = 92/333 (27%)
Query: 1424 CRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1481
CR P V +G G DT+VF+C G+ L+G I C +++ W PSPP C
Sbjct: 239 CRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC-DADSK--WNPSPPACE 295
Query: 1482 APCGGNLTGSSGFILSPNFPH------PYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1535
NL P+ PH P P D YV+ + + P Y
Sbjct: 296 PNSCINL---------PDIPHASWETYPRPTKEDV---------YVVGTV-LRYRCHPGY 336
Query: 1536 DFLYIYDGPDSNSPLIGSFQDSK------------LPE-RIESSSNTMHLAFR-SDGSVS 1581
P ++ P Q + PE ++ + T H R ++ V
Sbjct: 337 K-------PTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVY 389
Query: 1582 YTGFHLEYK-----------------AKLRESCFD----PGNIMNGTRLGMDYKLGST-- 1618
+ G + + + SC D P I +G YK S+
Sbjct: 390 FYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHG-----HYKQSSSYS 444
Query: 1619 -----VTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGS-RSTGSEGTVLSP 1672
+ Y CD GY+L G + L+C W+ P C A C +V
Sbjct: 445 FFKEEIIYECDKGYILVGQAKLSCSYSH-----WSAPAPQCKALCRKPELVNGRLSVDKD 499
Query: 1673 NY--PKNYSVGHNCVYSIAVPKEFVVFGQFVFF 1703
Y P+N ++ + Y + P+ G ++
Sbjct: 500 QYVEPENVTIQCDSGYGVVGPQSITCSGNRTWY 532
Score = 42.0 bits (97), Expect = 0.011
Identities = 57/237 (24%), Positives = 77/237 (32%), Gaps = 64/237 (27%)
Query: 906 CLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 961
C PG +G+ D S GS + FSC G+ L CE + WSHPLP C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 962 L-C--GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1018
+ C D+R + G FY + T++ D F L H
Sbjct: 173 VKCKPPPDIRNGRHS----GEENFYAYGFSVTYSCD-----------PRFSLLGHASISC 217
Query: 1019 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1078
EN + PPT IT C
Sbjct: 218 TVENETIG------VWRPSPPTCE------------------------KIT--------C 239
Query: 1079 EDPGIPQYGSRIGFN--FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
P + GF + DT+ F C G+ L G+S I C + W+ P C
Sbjct: 240 RKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSK--WNPSPPAC 294
Score = 41.2 bits (95), Expect = 0.018
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 1597 CFDPGNIMNGTRLGMD--YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
C P +I NG G + Y G +VTY CD + L G+++++C + ++ W + P+C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 1655 HAPCGSRSTGSEGTVLS 1671
+ S G ++S
Sbjct: 235 EKITCRKPDVSHGEMVS 251
Score = 40.4 bits (93), Expect = 0.031
Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 3/40 (7%)
Query: 2140 QTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2179
+ I +EC GY L+G + L+C + +W+ P P+C+ALC
Sbjct: 448 EEIIYECDKGYILVGQAKLSCSYS---HWSAPAPQCKALC 484
Score = 40.0 bits (92), Expect = 0.041
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERL--QMDGAPPVC 2348
C+PPP + N E++ + G + Y C P F+L+G+A ++C + +PP C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 2349 Q 2349
+
Sbjct: 235 E 235
Score = 38.5 bits (88), Expect = 0.12
Identities = 62/263 (23%), Positives = 87/263 (33%), Gaps = 65/263 (24%)
Query: 2133 GNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYS 2192
G + TI F+C G+ L G+S + C WN P CE N I
Sbjct: 254 GPIYNYKDTIVFKCQKGFVLRGSSVIHC--DADSKWNPSPPACEP---------NSCINL 302
Query: 2193 PGYP----DEYPNFQDCFWLVRVPPGNGIYINFTVLQT------EPIYDFITV------- 2235
P P + YP P +Y+ TVL+ +P D T
Sbjct: 303 PDIPHASWETYPR----------PTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 2236 ----WDG--------PDQNSPQIGQF-SGNTALESVYSTSNQILIKFHSDFTTSGFFVLS 2282
+ G P N+ +I Q A VY ++I H TS F +
Sbjct: 353 RWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE---TSRFSAIC 409
Query: 2283 YH--AYQLR------VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2334
+ R +C PP + + + I Y+C G+ LVG A L+C
Sbjct: 410 QGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCS 469
Query: 2335 LGERLQMDGAPPVCQVLCPANEL 2357
P C+ LC EL
Sbjct: 470 YS---HWSAPAPQCKALCRKPEL 489
Score = 37.0 bits (84), Expect = 0.35
Identities = 91/453 (20%), Positives = 146/453 (32%), Gaps = 85/453 (18%)
Query: 177 SCGNP-----GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQ-LTCIANSVNTASWDF 230
+CG P P L TRF G ++Y+C+ GY+ Q LTC ++ +
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFC 108
Query: 231 PVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE 290
CR G G I + SF ++ + + ++ +
Sbjct: 109 IYKRCRHP---GELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSH 165
Query: 291 KYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
EI +PP P I N H ++ + Y GFS Y F
Sbjct: 166 PLPQCEIVKCKPP-----------PDIRNGR----HSGEENFYAY-GFSVTYSCDPR--F 207
Query: 351 KSRGFKLFPGKDNSNKFSILNEGGIKTASNLC--PDPGEPENGKRIGSDFSLGSTVQFSC 408
G + + C PD E G ++ T+ F C
Sbjct: 208 SLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKC 267
Query: 409 DEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNA 468
+ +VL+G+ I C + + W+ P C+ +C + P ++ + P + D
Sbjct: 268 QKGFVLRGSSVIHC----DADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKED--- 320
Query: 469 QCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVS 528
V+V+ V + GY T +P TV +
Sbjct: 321 --VYVVGTV----------LRYRCHPGYKPTT-------DEPTTV-------------IC 348
Query: 529 MSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTP-LYGIREGDGFSNRDVLRFECQ 587
+ W Q E++ K+N EI + P +Y + FS + RF
Sbjct: 349 QKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF--- 405
Query: 588 FGFELIGEKSIVCQENNQWSANIP----ICIFP 616
S +CQ + WS P IC FP
Sbjct: 406 ---------SAICQGDGTWSPRTPSCGDICNFP 429
Score = 37.0 bits (84), Expect = 0.35
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 1078 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-V 1134
C PG + G I + G + FSCS G+ L G++ C R V WS PLP+C +
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 1135 AEC 1137
+C
Sbjct: 173 VKC 175
Score = 36.6 bits (83), Expect = 0.45
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 722 YNTFG-HNECPDPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVM 779
YNTF + C PG N + + GS I C EGF G+ T C + D V
Sbjct: 104 YNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLI-GSTTSRCEVQDRGVG 162
Query: 780 WSGLIPKC 787
WS +P+C
Sbjct: 163 WSHPLPQC 170
Score = 36.2 bits (82), Expect = 0.59
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 1948 CPEPQTPSSGIKIG-DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
C +P+ + + + D+Y+ + V+ QCD GY + G ITC R W +P C
Sbjct: 484 CRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGN--RTWYPEVPKC 538
Score = 32.7 bits (73), Expect = 6.5
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
Query: 151 FSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVG------DKIRYSC 204
FS TS F+ G + ++ SCG+ P + +G ++I Y C
Sbjct: 397 FSCHETSRFSAICQGDGTWSP--RTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYEC 454
Query: 205 VTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
GYIL G +L+C + + W P P C+A
Sbjct: 455 DKGYILVGQAKLSC-----SYSHWSAPAPQCKA 482
Score = 32.3 bits (72), Expect = 8.5
Identities = 11/40 (27%), Positives = 20/40 (50%)
Query: 574 DGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
D + + + +C G+ ++G +SI C N W +P C
Sbjct: 499 DQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 [Homo
sapiens]
Length = 809
Score = 192 bits (487), Expect = 6e-48
Identities = 168/681 (24%), Positives = 278/681 (40%), Gaps = 87/681 (12%)
Query: 1417 SSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPS 1476
S + +C P P +G + PG T F CD GY+LQGEE + C+ R W
Sbjct: 169 SPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGE 227
Query: 1477 PPVCIAPCGGNLTGSS-GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1535
P C+A CGG + ++ G I+SP + C W I + L F S++ +
Sbjct: 228 TPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 287
Query: 1536 DFLYIYDGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1594
D L + G SP+I +PER + S + ++++ S+ + L ++A
Sbjct: 288 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEE 347
Query: 1595 ESCFDP----GNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGY---STLTCIMGDDGRPGW 1647
+ CF P GN+ T +Y+ G+ T+ C GY L+ + + C+ D P W
Sbjct: 348 DRCFAPFLAHGNV---TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEPHW 402
Query: 1648 NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL 1707
N P+C A CG + G VLSP++P++YS G +CV+ + V +E + Q
Sbjct: 403 NDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE 462
Query: 1708 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTS----VGPITAKGFHFVY 1763
D++ ++DG + +L+ L G L LSSG +T++F + P +GF +
Sbjct: 463 GDMLTLFDGDGPSARVLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHF 521
Query: 1764 QAVPRTSSTQCSSVPEPRFGRRIGN--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1821
+ VPR + C +P P +G R + + G+ + + C PGY L GS + C
Sbjct: 522 KEVPRNDT--CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC------- 572
Query: 1822 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SF 1880
QW+ S C I+T ++ G+ D P G+ +Q + + +
Sbjct: 573 -QWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF--------PVGSHVQYRCLPGY 623
Query: 1881 ATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 1940
+ E A L YS D +
Sbjct: 624 SLE--------------GAAMLTCYS--------------------RDTGTPKWSDRVPK 649
Query: 1941 TAIGLDSCPEPQTPSSGIK--IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 1998
A+ + C P P +G + Y G+ + F C +G+ L G ITC+PG +W
Sbjct: 650 CALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTS 709
Query: 1999 PIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF------GVHLQFVNF 2052
P+C + + + P + I LP+G GV++ +
Sbjct: 710 QPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKL 769
Query: 2053 STETIHDYLEVRSGSSETSTV 2073
+++ + SGS S +
Sbjct: 770 QGKSLFGF----SGSHSYSPI 786
Score = 180 bits (456), Expect = 3e-44
Identities = 157/595 (26%), Positives = 249/595 (41%), Gaps = 74/595 (12%)
Query: 905 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHW--WSHPLPTCDAL 962
SC P P HG D G T +F CDSGY+L EE L+C W+ P+C A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 234
Query: 963 CGGDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1021
CGG + + G I+SP +L C W ++ G+ + +F L++ +D L++
Sbjct: 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRS 294
Query: 1022 NGSFTQPLARLTGSDLPPTINAGLYGNFRA-QLRFISDFSISYEGFNITFSEYNLEPCED 1080
GS P+ + SD+ GL + ++ + +S+ + ++ F + + C
Sbjct: 295 GGSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 352
Query: 1081 PGIPQYG-SRIGFNFGIGDTLTFSCSSGYRLEGT---SEIICLGGGRRVWSAPLPRCVAE 1136
P + + + G TFSC GY LE + I C+ W+ P C A
Sbjct: 353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 412
Query: 1137 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK 1196
CG + G++LSP++P +Y +C++ + VQ K I + ++ +GD+L ++DG
Sbjct: 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGD 472
Query: 1197 DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNS----DTEGTDEGFQLVYTSFELSH-CE 1251
+ +L G R LSS L L+F + G +GF L + + C
Sbjct: 473 GPSARVLAQLRGPQPRRRLLSS-GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 531
Query: 1252 DPGIPQFGYKISDQGH-FAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IA 1308
+ P++G++ + G G+ + Y C PGY L GS +L C +W P+C I
Sbjct: 532 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIM 589
Query: 1309 ECGGRFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRV 1367
C + + R S G+P RC+ PG SL+ A T S D
Sbjct: 590 TCADPGEIANGHRTASDAGFPVGSHVQYRCL------PG--YSLEGAAMLTCYSRDT--- 638
Query: 1368 WDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDP 1427
P +D + K A+++ C +P
Sbjct: 639 -GTPKWSDRVPK--------------------------------CALKYE-----PCLNP 660
Query: 1428 GVPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
GVP NG T + G+++ F C G+EL GE ITC+ W PP+C
Sbjct: 661 GVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ-WTSQPPLC 714
Score = 175 bits (443), Expect = 8e-43
Identities = 152/555 (27%), Positives = 234/555 (42%), Gaps = 36/555 (6%)
Query: 2114 AYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLP 2173
AY L PRP +G V D G T +F C GY L G L CL+G +WN P
Sbjct: 171 AYLLSCGFPPRP-AHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETP 229
Query: 2174 RCEALCGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDF 2232
C A CGG I A G I SP C W++ G ++++F + + D
Sbjct: 230 SCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDR 289
Query: 2233 ITVWDGPDQNSPQIGQFSGNTALE-SVYSTSNQILIKFHSDFTTSGFFV-LSYHAYQLRV 2290
+ V G SP I + E + S + + ++ S+ + + L + A++
Sbjct: 290 LMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 349
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTL----VGNAILTCRLGERLQMDGAPP 2346
C P + + + T D E+ G + + CLPG+ L NAI C + P
Sbjct: 350 CF-APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAI-ECVDPTEPHWNDTEP 407
Query: 2347 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2406
C+ +C EL + GV+LSP +P SY Q C W + V++ I + VE +E D
Sbjct: 408 ACKAMC-GGELS-EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNV-REGD 464
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
+L ++DG + VL L G + S+G ++ LQ+ A G G ++ +
Sbjct: 465 MLTLFDGDGPSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 523
Query: 2467 TPES-------PPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWD 2517
P + PP + + G L +V+ + C+ G+ L+G C+ +W
Sbjct: 524 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL----SWS 579
Query: 2518 APVPACQAI-SCGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDG 2574
A PACQ I +C P NG +D + VG+ V Y C GY L + T + G
Sbjct: 580 AAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTG 639
Query: 2575 TWSNHNKTPRCVV--ISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVREC 2630
T ++ P+C + C P NG + + Y G + F C GF L+G C
Sbjct: 640 TPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC 699
Query: 2631 LSS--GLWSESETRC 2643
+ W+ C
Sbjct: 700 VPGHPSQWTSQPPLC 714
Score = 174 bits (440), Expect = 2e-42
Identities = 152/596 (25%), Positives = 233/596 (39%), Gaps = 73/596 (12%)
Query: 1947 SCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
SC P P+ G + + D + G +F CD GY LQG + C+ G WN P C+A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 233
Query: 2006 QCGGAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2064
CGG + + + G I+SP G +L C W I G +HL F S + +D L VR
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 2065 SGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDP 2123
SG S S VI +P L S + S+ N + ++A++ C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 2124 RPFRNGFVIGND--FTVGQTISFECFPGYTLIGN---SALTCLHGVSRNWNHPLPRCEAL 2178
+G V D + G +F C PGY L +A+ C+ +WN P C+A+
Sbjct: 354 F-LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 412
Query: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238
CGG ++ G + SP +P Y QDC W V V I + +L D +T++DG
Sbjct: 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLFDG 471
Query: 2239 PDQNSPQIGQFSGNTALESVYSTSNQILIKFH------SDFTTSGFFVLSYHAYQLRVCQ 2292
++ + Q G + S+ + ++F + GF + + C
Sbjct: 472 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCP 531
Query: 2293 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2352
PP + G ++ YQC PG+ L+G+ ILTC+ L APP CQ
Sbjct: 532 ELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQ--- 586
Query: 2353 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2412
+ CA + G+ ++ F V
Sbjct: 587 -----------------------KIMTCADPGEIANGHRTA-------SDAGFPV----- 611
Query: 2413 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---CSTPE 2469
G ++Q Y + G + +S D G K R+ A C P
Sbjct: 612 GSHVQ----------YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 661
Query: 2470 SPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
P +GY + + Q +R+ C GF L+G+ + C W + P C+
Sbjct: 662 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS--QWTSQPPLCK 715
Score = 161 bits (407), Expect = 1e-38
Identities = 145/598 (24%), Positives = 236/598 (39%), Gaps = 78/598 (13%)
Query: 1774 CSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1833
C P P G + G + F C+ GY L G + C + + WN P+C+
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSCMA 233
Query: 1834 PCGGILTKRK-GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1892
CGG + G I+SP NL C W I EG + + + + + D L
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 1893 DGGDNNAPRLGSYSGTTIPHL-LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEP 1951
GG +P + +P L S + +LY+ S+ + L + A D C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 1952 QTPSSGIKIGD-RYMVGDVVSFQCDQGYSLQ---GHSHITCMPGPVRRWNYPIPICLAQC 2007
+ D Y G + +F C GY+L+ + I C+ WN P C A C
Sbjct: 354 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 413
Query: 2008 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2067
GG +S+ +GV+LSP +P +Y DC W +++ + LQ V D L + G
Sbjct: 414 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQ-VEILNVREGDMLTLFDGD 472
Query: 2068 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNK----QGFHIVY-QAYQLQSCPD 2122
++ V+ +L GPQ L S+ + +L F + QGF + + + + +CP+
Sbjct: 473 GPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 532
Query: 2123 PRPFRNGFVIGN--DFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-- 2178
P G+ + D G ++++C PGY L+G+ LTC +S W+ P C+ +
Sbjct: 533 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLS--WSAAPPACQKIMT 590
Query: 2179 CG--GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW 2236
C G I + T G+P G ++ + L P Y
Sbjct: 591 CADPGEIANGHRTASDAGFP------------------VGSHVQYRCL---PGYSL---- 625
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKF----HSDFTTSGFFVLSYHAYQLRVCQ 2292
+ + + +S +T + +K+ + +G+ L H YQ
Sbjct: 626 ----EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQ----- 676
Query: 2293 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
G+ +R+ C GF L+G +TC G Q PP+C+V
Sbjct: 677 ------------------AGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 716
Score = 155 bits (391), Expect = 9e-37
Identities = 115/438 (26%), Positives = 186/438 (42%), Gaps = 18/438 (4%)
Query: 559 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFP 616
SCG P P +G F C G++L GE++++C + W+ P C+
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 234
Query: 617 CLSNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 675
C A +G ++SP+ G NL C W I + G R+HL F L+ D L V+
Sbjct: 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRS 294
Query: 676 GDSPESPILGTFTGAEVPSH-LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 734
G SP SP++ +VP L S++ L +E ++ + ++ + F + C P
Sbjct: 295 GGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPF 354
Query: 735 IPI-NARRFGDNFQLGSSISVICEEGF-IKTQGTETITCILMDGKVMWSGLIPKCGAPCG 792
+ N ++ G+ + C G+ ++ G + + W+ P C A CG
Sbjct: 355 LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCG 414
Query: 793 GHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 852
G S P+GV+LSP WP Y +C W + + I + E D+L + DG
Sbjct: 415 GELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDG 473
Query: 853 LLSPLLGSYNGTQVPQFLFSSSNFIYLLFTT----DNSRSNNGFKIHYESVTVNTYSCLD 908
+ +L G Q + L SS + L F N GF +H++ V N +C +
Sbjct: 474 PSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRND-TCPE 532
Query: 909 PGIPVHGRRYGH--DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL--CG 964
P G R D G+ +++ C+ GY L + L C+ + WS P C + C
Sbjct: 533 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCA 592
Query: 965 --GDVRGPSGTILSPGYP 980
G++ T G+P
Sbjct: 593 DPGEIANGHRTASDAGFP 610
Score = 148 bits (373), Expect = 1e-34
Identities = 122/456 (26%), Positives = 189/456 (41%), Gaps = 25/456 (5%)
Query: 1247 LSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1306
L C P P G +S G T + C+ GY L G L C+ G R +W+ PSC
Sbjct: 173 LLSCGFPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Query: 1307 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR 1366
+A CGG + GRI+SP NL C W+IE G + L F + +D L
Sbjct: 232 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 291
Query: 1367 VWDGPPENDMLLKEISGSLIPE-GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACR 1425
V G ++ + +PE G+ S + ++ ++ + +++F + C
Sbjct: 292 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 351
Query: 1426 DPGVPM-NGTRNGDGREPGDTVVFQCDPGYELQ---GEERITCIQVENRYFWQPSPPVCI 1481
P + N T PG F C PGY L+ I C+ + W + P C
Sbjct: 352 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACK 410
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
A CGG L+ +G +LSP++P Y +DC W + V + I L ++ D L ++
Sbjct: 411 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLF 469
Query: 1542 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSY----TGFHLEYKAKLR-ES 1596
DG ++ ++ + + R+ SS + L F++ GF L +K R ++
Sbjct: 470 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 529
Query: 1597 C--FDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
C P T D G+ +TY C+ GY L G LTC W+ A P+C
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPAC 585
Query: 1655 H-----APCGSRSTGSEGTVLSPNYPKNYSVGHNCV 1685
A G + G T +P V + C+
Sbjct: 586 QKIMTCADPGEIANGHR-TASDAGFPVGSHVQYRCL 620
Score = 145 bits (367), Expect = 5e-34
Identities = 164/663 (24%), Positives = 249/663 (37%), Gaps = 86/663 (12%)
Query: 1596 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH 1655
SC P +G D G T T++CD+GY LQG TL C+ G RP WN PSC
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCM 232
Query: 1656 APCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL---HDVV 1711
A CG + G ++SP +VG N + F + SL +D +
Sbjct: 233 ASCGGTIHNATLGRIVSPE--PGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 1712 EVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSS 1771
V G + S ++ E +S + + S P ++A
Sbjct: 291 MVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAF---EE 347
Query: 1772 TQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGS---IAIRCETVPNSLAQWND 1826
+C + P G E+ G+ F C PGY L AI C V + WND
Sbjct: 348 DRCFA-PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC--VDPTEPHWND 404
Query: 1827 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1886
+ P C CGG L++ G +LSP +P+ Y +CVW + V E I +QV
Sbjct: 405 TEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQV-EILNVREG 463
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVS----AAGFHLEYTA 1942
D L +DG +A L G L S+ +L L FQ+ GF L +
Sbjct: 464 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 523
Query: 1943 IGL-DSCPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 1999
+ D+CPE P G + + G V+++QC+ GY L G +TC W+
Sbjct: 524 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAA 581
Query: 2000 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2059
P C I++ PG + P+G H+Q+ ++
Sbjct: 582 PPACQK------------IMTCADPGEIANGHRTASDAGFPVGS--HVQYRCLPGYSLEG 627
Query: 2060 YLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2119
+ S +T T K + A + +
Sbjct: 628 AAMLTCYSRDTGTP-------------------------------KWSDRVPKCALKYEP 656
Query: 2120 CPDPRPFRNGF--VIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC-- 2175
C +P NG+ + + + G+++ F C+ G+ LIG +TC+ G W P C
Sbjct: 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 716
Query: 2176 ---EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWL---VRVPPGNGIYINFTVLQTEPI 2229
E L + T P E N L + + G+G+YI +T LQ + +
Sbjct: 717 AYEELLDNRKLEVTQTT--DPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSL 774
Query: 2230 YDF 2232
+ F
Sbjct: 775 FGF 777
Score = 122 bits (307), Expect = 5e-27
Identities = 105/424 (24%), Positives = 179/424 (42%), Gaps = 32/424 (7%)
Query: 382 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 441
C P P +G +D G T F CD Y LQG +++ C + +W+ P C +
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSC-M 232
Query: 442 KTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
+CG + + G SP N C WVI A + + ++FE L+ D L
Sbjct: 233 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLM 291
Query: 501 IGDGGEVGDPRTVLQVLTGSFVPDL----IVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 556
+ GG P V+ S + D+ ++S + +++ L ++ + + ++ E
Sbjct: 292 VRSGGSPLSP-----VIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 346
Query: 557 KESCGDPGTPLYGIREGD-GFSNRDVLRFECQFGFELI---GEKSIVCQENNQ--WSANI 610
++ C P + D + + F C G+ L +I C + + W+
Sbjct: 347 EDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTE 406
Query: 611 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDF 670
P C C + P G VLSPD+P+ Y +C+W + RI L ++ + D
Sbjct: 407 PACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDM 465
Query: 671 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQA----DHSMSGRGFNITYNTFG 726
L + DGD P + +L G + L S+ L L+FQA + G+GF + +
Sbjct: 466 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 525
Query: 727 HNE-CPDPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 783
N+ CP+ P R + L G+ ++ CE G+ + G++ +TC + WS
Sbjct: 526 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAA 581
Query: 784 IPKC 787
P C
Sbjct: 582 PPAC 585
Score = 122 bits (306), Expect = 6e-27
Identities = 127/455 (27%), Positives = 190/455 (41%), Gaps = 62/455 (13%)
Query: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
SCG P P G + T G + C +GY L G L C+ + SW+ P C
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCM 232
Query: 237 AEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYL 295
A +CGGT+ ++ G I SP N C W I A G + L F ++E D L
Sbjct: 233 A--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 296 EI-EGSEP--PTIWLSGMNIPPP--IISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
+ G P P I+ S M+ P +IS+ L + ++++ S ++ +
Sbjct: 291 MVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE---- 346
Query: 351 KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDE 410
+ R F F L G + T DP ++ G+ FSC
Sbjct: 347 EDRCFAPF-----------LAHGNVTTT-----DP-----------EYRPGALATFSCLP 379
Query: 411 DYVLQ---GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSN 467
Y L+ +I C E W+D P CK CG L P+G SP++P Y
Sbjct: 380 GYALEPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPG 436
Query: 468 AQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIV 527
CVW + V K I + E ++ G D LT+ DG G VL L G ++
Sbjct: 437 QDCVWGV-HVQEEKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLL 492
Query: 528 SMSSQMWLHLQT-----DESVGSVGFKVNYKEIEK-ESCGDPGTPLYGIR---EGDGFSN 578
S + L Q + +G GF +++KE+ + ++C + P +G R GD
Sbjct: 493 SSGPDLTLQFQAPPGPPNPGLGQ-GFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIR 550
Query: 579 RDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
VL ++C+ G+EL+G + CQ + WSA P C
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Score = 94.7 bits (234), Expect = 1e-18
Identities = 60/170 (35%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 3019 DYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAV-TCPTPPQISNGRLEG 3077
D + G ++Y C+PGY EL GS I TC + +WS P C+ + TC P +I+NG
Sbjct: 547 DLIRGTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA 604
Query: 3078 TN--FDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPKF--CGDPGIPA 3129
++ F G + Y C PGY L A+LTC G WS VP+C K+ C +PG+P
Sbjct: 605 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 664
Query: 3130 QGKREGKSFIYQS--EVSFSCNFPFILVGSSTRICQA--DGTWSGSSPHC 3175
G + YQ+ + F C F L+G T C W+ P C
Sbjct: 665 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 92.0 bits (227), Expect = 9e-18
Identities = 106/445 (23%), Positives = 163/445 (36%), Gaps = 75/445 (16%)
Query: 54 TVSCVKGFIYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFAL 112
T SC+ +CGGT+ G I SP C WVI A E R+ + F+ +L
Sbjct: 228 TPSCMA----SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSL 283
Query: 113 EEEYDYLSLYDGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 170
+E+ D L + G P + + + ++ +S++ + L S+ + + +
Sbjct: 284 DEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY-VELLSETPANPLLLSLRF 342
Query: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILD--GHPQ-LTCIANSVNTA 226
E + C P + V + G +SC+ GY L+ G P + C+
Sbjct: 343 EAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECV--DPTEP 400
Query: 227 SWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF 286
W+ P C+A CGG + +G++ SP +P Y DC W + + I L
Sbjct: 401 HWNDTEPACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEIL 458
Query: 287 QMEEKYDYLEIEGSEPPTIWLSGMNIPPP---IISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
+ E +G P L+ + P P ++S+ L L F G +
Sbjct: 459 NVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFV 518
Query: 344 VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASN----------------------- 380
+ FK P D + E G +TAS+
Sbjct: 519 LH---------FKEVPRNDTCPELP-PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 568
Query: 381 ---------------------LCPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGA 417
C DPGE NG R SD F +GS VQ+ C Y L+GA
Sbjct: 569 ILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGA 628
Query: 418 KSITCQRIAEVFAAWSDHRPVCKVK 442
+TC WSD P C +K
Sbjct: 629 AMLTCYSRDTGTPKWSDRVPKCALK 653
Score = 88.2 bits (217), Expect = 1e-16
Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 16/189 (8%)
Query: 2886 TCGDPGTPGHGSRQESN--FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC-KA 2942
TC + P G R S+ + + Y C+ GY L GS+ TC + SW+ P C K
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 2943 VQCGNPGTTANGKVFRID-GTTFSSSVIYSCMEGYILSGPSVRQCTANGT----WSGTLP 2997
+ C +PG ANG D G S V Y C+ GY L G ++ C + T WS +P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 2998 NCTI--ISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN--GT 3051
C + C +PG+P NG + Y Y G+++ + C G+ EL G TC
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGF--ELIGEVTITCVPGHPSQ 706
Query: 3052 WSGVMPTCR 3060
W+ P C+
Sbjct: 707 WTSQPPLCK 715
Score = 84.0 bits (206), Expect = 2e-15
Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
N + P +P HG+ GTV+ Y C PGY L GS +L CQ + W P C
Sbjct: 527 NDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 586
Query: 2823 MI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG----HWSGS 2875
I C PG N S + GS V Y C SL G + TC WS
Sbjct: 587 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR 646
Query: 2876 QPHCSGDATGTCGDPGTP--GHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN--G 2931
P C+ C +PG P G+ + + +++ ++R+ C G+ L G TC+
Sbjct: 647 VPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPS 705
Query: 2932 SWTGRQPECK 2941
WT + P CK
Sbjct: 706 QWTSQPPLCK 715
Score = 83.2 bits (204), Expect = 4e-15
Identities = 62/187 (33%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 3063 TCPTPPQISNGRLEGTNFDW--GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP- 3119
TCP P G ++ D G ++Y C PGYEL +LTC + +WS P C
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 3120 KFCGDPGIPAQGKREGK--SFIYQSEVSFSCNFPFILVGSSTRICQADGT----WSGSSP 3173
C DPG A G R F S V + C + L G++ C + T WS P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 3174 HCIEPTQTSCENPGVPRHGSQN-NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLP--DLTW 3230
C + C NPGVP +G Q +Q G ++F C +G L G T TC+P W
Sbjct: 649 KCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQW 707
Query: 3231 SGIQPEC 3237
+ P C
Sbjct: 708 TSQPPLC 714
Score = 82.4 bits (202), Expect = 7e-15
Identities = 53/167 (31%), Positives = 74/167 (44%), Gaps = 14/167 (8%)
Query: 2667 RDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV-SCGHPGSPIYGR--TSGNGF 2722
R TV+ YQC PG+ L+GS + CQ D +WS P+C + +C PG G S GF
Sbjct: 550 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 609
Query: 2723 NFNDVVTFSCNIGYLMQGPTKAQCQA----NRQWSHPPPMC--KVVNCSDPGIPANSKRE 2776
V + C GY ++G C + +WS P C K C +PG+P N +
Sbjct: 610 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQT 669
Query: 2777 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPEC 2821
H + G + + C G+ L G + C P QW P C
Sbjct: 670 LYKHH--YQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 67.8 bits (164), Expect = 2e-10
Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 15/188 (7%)
Query: 2589 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA- 2645
+C ELP P G + + G+ + C+ G+ L+GS + C WS + C
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 2646 GHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDHN----WSGQLP 2699
C P I NG + G+ V Y+C PG+ L G+++ C WS ++P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 2700 SCVPV--SCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR--QWS 2753
C C +PG P G + + + + + F C G+ + G C QW+
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 708
Query: 2754 HPPPMCKV 2761
PP+CKV
Sbjct: 709 SQPPLCKV 716
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 3178 PTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPE 3236
P +C P G + + G + G+V+ + C+ G+ L GS TC DL+WS P
Sbjct: 525 PRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 584
Query: 3237 CIP-HSCKQPETPAH----ANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT-- 3289
C +C P A+ A+ G + SH + Y C PG+ L G C S +T
Sbjct: 585 CQKIMTCADPGEIANGHRTASDAGFPVGSH---VQYRCLPGYSLEGAA-MLTCYSRDTGT 640
Query: 3290 --WTGKVPIC 3297
W+ +VP C
Sbjct: 641 PKWSDRVPKC 650
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/77 (40%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 2886 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG---SWTGRQPECKA 2942
+CG P P HG ++ T + CD+GY L G E CL NG SW G P C A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA 233
Query: 2943 VQCGNPGTTANGKVFRI 2959
CG GT N + RI
Sbjct: 234 -SCG--GTIHNATLGRI 247
Score = 44.3 bits (103), Expect = 0.002
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 173 LQSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
L+ C NPGVP G LY + G+ +R+ C G+ L G +TC+ + + W
Sbjct: 652 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG--HPSQWTS 709
Query: 231 PVPICR 236
P+C+
Sbjct: 710 QPPLCK 715
Score = 43.9 bits (102), Expect = 0.003
Identities = 39/148 (26%), Positives = 56/148 (37%), Gaps = 14/148 (9%)
Query: 1595 ESCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
E C +PG NG T Y+ G ++ ++C G+ L G T+TC+ G + W P
Sbjct: 655 EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPP 712
Query: 1653 SCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE 1712
C + V P G N +I +P V+ L V
Sbjct: 713 LCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIV---------LGSGVY 763
Query: 1713 VYDGPTQQSSLLSSLSGSHSGESLPLSS 1740
+Y Q SL SGSHS + + S
Sbjct: 764 IYYTKLQGKSLF-GFSGSHSYSPITVES 790
Score = 43.1 bits (100), Expect = 0.005
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 9/99 (9%)
Query: 3032 PGYTMELNGSRIRTCTINGTWSGVMPTCRA----VTCPTPPQISNGRLEGTNFDWGFSIS 3087
PG + G T T T + V T + ++C PP+ ++G + T+ G + +
Sbjct: 140 PGPPLGPEGGEEETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTAT 199
Query: 3088 YICSPGYELSFPAVLTCVGNGT---WSGEVPQCLPKFCG 3123
+ C GY+L L C+ NGT W+GE P C+ CG
Sbjct: 200 FHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMAS-CG 236
Score = 41.6 bits (96), Expect = 0.014
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 4/105 (3%)
Query: 2563 KELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFML 2622
+E TT + + T T ++SCG P P +G+ T G TA F CD G+ L
Sbjct: 151 EETTTTIITT--TTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQL 208
Query: 2623 VGSAVRECLSS--GLWSESETRCLAGHCGIPELIVNGQVIGENYG 2665
G CL+ W+ C+A G G+++ G
Sbjct: 209 QGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPG 253
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 555 IEKESCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVCQEN--NQWSANI 610
++ E C +PG P G + + + LRF C GFELIGE +I C +QW++
Sbjct: 652 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQP 711
Query: 611 PIC 613
P+C
Sbjct: 712 PLC 714
Score = 40.4 bits (93), Expect = 0.031
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 3182 SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL--TWSGIQPECI 3238
SC P P HG + T G FHC G+ LQG T CL +W+G P C+
Sbjct: 175 SCGFPPRPAHGDVSVT-DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Score = 38.5 bits (88), Expect = 0.12
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 3001 IISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMP 3057
++SCG P PA+G D G ++ C GY +L G C +NGT W+G P
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGY--QLQGEETLIC-LNGTRPSWNGETP 229
Query: 3058 TCRAVTCPTPPQISNGRL 3075
+C A T + GR+
Sbjct: 230 SCMASCGGTIHNATLGRI 247
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 2648 CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSCVPVS 2705
CG P +G V + T + C+ G++L G IC +W+G+ PSC+ S
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-AS 234
Query: 2706 CG 2707
CG
Sbjct: 235 CG 236
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 382 CPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
C +PG PENG + + G +++F C E + L G +ITC + + W+ P+C
Sbjct: 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLC 714
Query: 440 KV 441
KV
Sbjct: 715 KV 716
Score = 35.8 bits (81), Expect = 0.77
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 2704 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMC 2759
+SCG P P +G S + TF C+ GY +QG C W+ P C
Sbjct: 174 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Score = 34.7 bits (78), Expect = 1.7
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 4/67 (5%)
Query: 2823 MIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG---HWSGSQPHC 2879
++ CG P P + +S G T + C L G+ + C LNG W+G P C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLIC-LNGTRPSWNGETPSC 231
Query: 2880 SGDATGT 2886
GT
Sbjct: 232 MASCGGT 238
Score = 34.3 bits (77), Expect = 2.2
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 3241 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDN--TWTGKVPICE 3298
SC P PAH +V DL G T + C G+ L G E +C + +W G+ P C
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGG-TATFHCDSGYQLQ-GEETLICLNGTRPSWNGETPSCM 232
Query: 3299 A 3299
A
Sbjct: 233 A 233
Score = 34.3 bits (77), Expect = 2.2
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 3442 LNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT--QYTGCSVH 3499
L +++ ++ S Q G N +A+AIL+P +I G G Y+Y + K+ ++G +
Sbjct: 727 LEVTQTTDPSRQLEGGN---LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSY 783
Query: 3500 ENNNGQAAFENPMYD 3514
++ F NP+Y+
Sbjct: 784 SPITVESDFSNPLYE 798
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 186 bits (473), Expect = 3e-46
Identities = 226/867 (26%), Positives = 349/867 (40%), Gaps = 111/867 (12%)
Query: 2490 WACDRGFRLVGKSSAVCRKSSYGYHAWDA--PVPACQAISCGIPKAPTNGGILTTD---Y 2544
+ C G+R +G VCRK W A P+ CQ CG P G T +
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-----WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 2545 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGT 2604
G + Y CN+GY+L E+ C +DG W+ N P C V+ C + P NG + +
Sbjct: 105 EYGVKAVYTCNEGYQLLG-EINYRECDTDG-WT--NDIPICEVVKCLPVTAPENGKIVSS 160
Query: 2605 ------QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQ 2658
+ +G F C+ G+ + G C G WS+ + +C+ C P+ ++NG
Sbjct: 161 AMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPD-VINGS 219
Query: 2659 VIGENYGYRDT--VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSP---- 2712
I + Y++ Y+CN G+ +C + W LPSC SC +P P
Sbjct: 220 PISQKIIYKENERFQYKCNMGYEYSERGDAVCTES-GWR-PLPSCEEKSCDNPYIPNGDY 277
Query: 2713 ----IYGRTSGNGFNFNDVVTFSCNIGY--LMQGPTKAQCQANRQWSHPPPMCKVVNCSD 2766
I RT D +T+ C G+ +G T A+C + W P P C + C
Sbjct: 278 SPLRIKHRT-------GDEITYQCRNGFYPATRGNT-AKC-TSTGWI-PAPRCTLKPCDY 327
Query: 2767 PGIPANSKRESKIEHGNF--TYGTVVFYDCNPGYFLFGSSV---LICQPNGQWDKPLPEC 2821
P I + F G Y C+ + S + C +G W +P C
Sbjct: 328 PDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-C 385
Query: 2822 IMIDCGHP----GVPPNAVLSGEKYTFGSTVHYSC-TGKRSLLGQSSRTCQLNGHWSGSQ 2876
+ C P G N G K+ G ++ +C G Q++ TC NG WS +
Sbjct: 386 LR-KCYFPYLENGYNQN---HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT- 439
Query: 2877 PHCSGDATGTCGDPGTP---GHGSRQESNFRTKSTVRYACDTGYILHGSEER---TCLAN 2930
P C TC G S + + K +Y C GY+ E TC +
Sbjct: 440 PRCI--RVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKD 497
Query: 2931 GSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF--SSSVIYSCMEGYILSGPSVR---Q 2985
G W+ QP C C P N + + D T F + ++ Y C +GY + S
Sbjct: 498 G-WSA-QPTC-IKSCDIP-VFMNART-KNDFTWFKLNDTLDYECHDGYESNTGSTTGSIV 552
Query: 2986 CTANGTWSGTLPNCTIISCGDPGIPANGL--RYGDDYVVGQNVSYMCQPGYTMELNGSRI 3043
C NG WS LP C C P I + + R D Y VG+ + + C+PG+T + G
Sbjct: 553 CGYNG-WS-DLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFT--IVGPNS 608
Query: 3044 RTCTINGTWSGVMPTCR--AVTCPTPPQISNGRL-EGTNFDWGFS--ISYICSPGYELSF 3098
C G S +P C+ +C PP++ NG + E T ++G S + Y C+P + +
Sbjct: 609 VQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKG 667
Query: 3099 PAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPAQGKREGKS--FIYQSEVSFSCNFPFIL 3154
P + CV +G W+ +P C+ CGD G + S + Y V F+C+ F +
Sbjct: 668 PNKIQCV-DGEWT-TLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTM 725
Query: 3155 VGSSTRICQADGTWSGSSPHCIEPTQ-TSCENPG-VPRHGSQNNTFGFQVGSVVQFHC-- 3210
+G + C G W+ P C+ + C++ + N F S +++ C
Sbjct: 726 IGHRSITC-IHGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRG 783
Query: 3211 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ 3270
K+G + P++ S Q + P P+ P N+ G + CQ
Sbjct: 784 KEGWIHTVCINGRWDPEVNCSMAQIQLCP---PPPQIPNSHNMTTTLNYRDGEKVSVLCQ 840
Query: 3271 PGFFLAGGTEHRVCRSDNTWTGKVPIC 3297
+ + G E + D W +P+C
Sbjct: 841 ENYLIQEGEE--ITCKDGRWQ-SIPLC 864
Score = 171 bits (434), Expect = 9e-42
Identities = 256/1086 (23%), Positives = 423/1086 (38%), Gaps = 167/1086 (15%)
Query: 2291 CQPPPPVPNAEILTE----DDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2346
C P N +I++ D E+ G +R+ C G+ + G+ + C + P
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS-DDGFWSKEKPK 204
Query: 2347 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ------ 2400
++ C SP + P Q + + Y M E+ +
Sbjct: 205 CVEISCK-------------SPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVC 251
Query: 2401 TEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQ-----WSADHGNNKKG 2455
TE + L + + +P + + GDYS G E+ Q + A GN K
Sbjct: 252 TESGWRPLPSCEEKSCDNPYIPN--GDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKC 309
Query: 2456 FRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVR-------------WACDRGFRLVGKS 2502
+I T + P Y + GG + +R + CD F
Sbjct: 310 TSTGWIPAPRCTLK--PCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPS-- 365
Query: 2503 SAVCRKSSYGYH------AWDAPVPACQAISCGIPKAPT----NGGILTTDYLVGTRVTY 2552
SY H W VP + C P N G ++ G +
Sbjct: 366 ------GSYWDHIHCTQDGWSPAVPCLR--KCYFPYLENGYNQNHG---RKFVQGKSIDV 414
Query: 2553 FCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCV-VISCGELPTP-PNGNKIGTQTSYG- 2609
C+ GY L K TT C +G WS TPRC+ V +C + NG +Q +Y
Sbjct: 415 ACHPGYALP-KAQTTVTCMENG-WS---PTPRCIRVKTCSKSSIDIENGFISESQYTYAL 469
Query: 2610 -STAIFTCDLGFMLVGSAVRECLSSGL--WSESETRCLAGHCGIPELIVNGQVIGENYGY 2666
A + C LG++ ++ G WS T C+ C IP + +N + + +
Sbjct: 470 KEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPT-CIKS-CDIP-VFMNARTKNDFTWF 526
Query: 2667 R--DTVVYQCNPGFRL-IGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY--GRTSGNG 2721
+ DT+ Y+C+ G+ GS+ +N LP C C P ++ +
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQ 586
Query: 2722 FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK--VVNCSDPG--IPANSKRES 2777
+ +V+ FSC G+ + GP QC + S P+CK V +C P + N K ++
Sbjct: 587 YKVGEVLKFSCKPGFTIVGPNSVQCY-HFGLSPDLPICKEQVQSCGPPPELLNGNVKEKT 645
Query: 2778 KIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN--- 2834
K E+G + VV Y CNP + + G + + C +G+W LP CI+ + +P
Sbjct: 646 KEEYG---HSEVVEYYCNPRFLMKGPNKIQCV-DGEWTT-LPVCIVEESTCGDIPELEHG 700
Query: 2835 -AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG-DATGTCGDPGT 2892
A LS Y +G +V ++C+ +++G S TC ++G W+ P C D C
Sbjct: 701 WAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT-QLPQCVAIDKLKKCKSSNL 758
Query: 2893 P--GHGSRQESNFRTKSTVRYAC--DTGYILHGSEERTCLANGSWTGRQPECKAVQ---C 2945
+ + F S +RY C G+I T NG W + C Q C
Sbjct: 759 IILEEHLKNKKEFDHNSNIRYRCRGKEGWI------HTVCINGRWDP-EVNCSMAQIQLC 811
Query: 2946 GNPGTTANGKVFRIDGTTFS----SSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3001
P N TT + V C E Y++ C +G W ++P C
Sbjct: 812 PPPPQIPNSHNMT---TTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRWQ-SIPLCVE 866
Query: 3002 -ISCGDP-----GIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGV 3055
I C P G + + Y G +SY C+ G+ ++ TC + G WS
Sbjct: 867 KIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGF--RISEENETTCYM-GKWSSP 923
Query: 3056 MPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGE 3113
P C + C +PP+IS+G + ++ +G ++Y C G+ + PA+ C+G WS
Sbjct: 924 -PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWS-H 980
Query: 3114 VPQCLPKFC-----GDPGIPAQGKREGKSFIYQS--EVSFSCNFPFILVGSSTRICQADG 3166
P C+ C + IP K++ +Y++ +V+++C + + G+S C +
Sbjct: 981 PPSCIKTDCLSLPSFENAIPMGEKKD----VYKAGEQVTYTCATYYKMDGASNVTC-INS 1035
Query: 3167 TWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTC 3224
W+G P C TSC NP ++ + G V++ C+ + + G C
Sbjct: 1036 RWTG-RPTC---RDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC 1091
Query: 3225 LPDLTWSGIQPECIPHS--CKQPETPAHANVVGMDLPSH--GYTLIYTCQPGFFLAGGTE 3280
L + W+ P+C + C P + ++ L + ++ Y CQ + G +
Sbjct: 1092 L-NGNWTE-PPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQ-NLYQLEGNK 1148
Query: 3281 HRVCRS 3286
CR+
Sbjct: 1149 RITCRN 1154
Score = 169 bits (429), Expect = 3e-41
Identities = 216/873 (24%), Positives = 335/873 (38%), Gaps = 102/873 (11%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSVVR--WACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPA 2522
C P P G G V+ + C+ G++L+G+ + W +P
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTNDIPI 140
Query: 2523 CQAISCGIPKAPTNGGILTT------DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2576
C+ + C AP NG I+++ +Y G V + CN GY++ E C DG W
Sbjct: 141 CEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDE--EMHCSDDGFW 198
Query: 2577 SNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIF--TCDLGFMLVGSAVRECLSSG 2634
S + P+CV ISC + P NG+ I + Y F C++G+ C SG
Sbjct: 199 S--KEKPKCVEISC-KSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG 255
Query: 2635 LWSESETRCLAGHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDH 2692
W + C C P I NG +R D + YQC GF
Sbjct: 256 -WRPLPS-CEEKSCDNP-YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 2693 NWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIG--YLMQGPTKAQCQANR 2750
W P C C +P G N F +G Y + +
Sbjct: 313 GWI-PAPRCTLKPCDYPDIKHGGLYHENMRR----PYFPVAVGKYYSYYCDEHFETPSGS 367
Query: 2751 QWSHPPPMCKVVNCS----DPGIPANSK-------RESKIEHG-NFTYGTVVFYDCNPGY 2798
W H ++C+ P +P K HG F G + C+PGY
Sbjct: 368 YWDH-------IHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGY 420
Query: 2799 FL-FGSSVLICQPNGQWDKPLPECIMI-DCGHPGVP-PNAVLSGEKYTFG--STVHYSC- 2852
L + + C NG W P P CI + C + N +S +YT+ Y C
Sbjct: 421 ALPKAQTTVTCMENG-W-SPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCK 478
Query: 2853 TGKRSLLGQSSR--TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTV 2909
G + G++S TC +G WS +QP C +C P ++ + F+ T+
Sbjct: 479 LGYVTADGETSGSITCGKDG-WS-AQPTC----IKSCDIPVFMNARTKNDFTWFKLNDTL 532
Query: 2910 RYACDTGYILH-GSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFR-IDGTTFSSS 2967
Y C GY + GS + + + P C +C P + R D
Sbjct: 533 DYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEV 592
Query: 2968 VIYSCMEGYILSGPSVRQCTANGTWSGTLPNC--TIISCGDPGIPANG---LRYGDDYVV 3022
+ +SC G+ + GP+ QC G S LP C + SCG P NG + ++Y
Sbjct: 593 LKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGH 651
Query: 3023 GQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTC--RAVTCPTPPQISNG--RLEGT 3078
+ V Y C P + M+ G C ++G W+ +P C TC P++ +G +L
Sbjct: 652 SEVVEYYCNPRFLMK--GPNKIQC-VDGEWT-TLPVCIVEESTCGDIPELEHGWAQLSSP 707
Query: 3079 NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLP----KFCGDPG--IPAQGK 3132
+ +G S+ + CS + + +TC+ +G W+ ++PQC+ K C I +
Sbjct: 708 PYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLIILEEHL 765
Query: 3133 REGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG 3192
+ K F + S + + C G +C +G W + Q P +P
Sbjct: 766 KNKKEFDHNSNIRYRCRGK---EGWIHTVC-INGRWDPEVNCSMAQIQLCPPPPQIPNSH 821
Query: 3193 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH-SCKQPETPAHA 3251
+ T ++ G V C++ +L+Q TC D W I P C+ C QP H
Sbjct: 822 NMTTTLNYRDGEKVSVLCQENYLIQEGEEITC-KDGRWQSI-PLCVEKIPCSQPPQIEHG 879
Query: 3252 NV----VGMDLPSHGYTLIYTCQPGFFLAGGTE 3280
+ + +HG L YTC+ GF ++ E
Sbjct: 880 TINSSRSSQESYAHGTKLSYTCEGGFRISEENE 912
Score = 157 bits (398), Expect = 1e-37
Identities = 180/681 (26%), Positives = 264/681 (38%), Gaps = 144/681 (21%)
Query: 2483 QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAP-VPAC--QAISCGIPKAPTNGGI 2539
++ V++++C GF +VG +S C YH +P +P C Q SCG P NG +
Sbjct: 588 KVGEVLKFSCKPGFTIVGPNSVQC------YHFGLSPDLPICKEQVQSCGPPPELLNGNV 641
Query: 2540 ---LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVV--ISCGELP 2594
+Y V Y+CN + + V DG W+ P C+V +CG++P
Sbjct: 642 KEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV---DGEWTT---LPVCIVEESTCGDIP 695
Query: 2595 TPPNG--NKIGTQTSYGSTAIFTCDLGFMLVG--------------------SAVRECLS 2632
+G YG + F C F ++G +++C S
Sbjct: 696 ELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKS 755
Query: 2633 SGLWSESE--------------------------TRCLAGH--------------CGIPE 2652
S L E T C+ G C P
Sbjct: 756 SNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPP 815
Query: 2653 LIVNGQVIGENYGYRD--TVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVP-VSCGHP 2709
I N + YRD V C + LI I +D W +P CV + C P
Sbjct: 816 QIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQS-IPLCVEKIPCSQP 873
Query: 2710 GSPIYG-----RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNC 2764
+G R+S + ++++C G+ + + C + WS PP C+ + C
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGK-WSSPP-QCEGLPC 931
Query: 2765 SDPGIPANSKRESKIEHG-------NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKP 2817
P +I HG ++ YG V Y C G+ + G ++ C +W P
Sbjct: 932 KSP---------PEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWSHP 981
Query: 2818 LPECIMIDCGHPGVPPNAVLSGEK---YTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 2874
P CI DC NA+ GEK Y G V Y+C + G S+ TC +N W+G
Sbjct: 982 -PSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC-INSRWTG 1039
Query: 2875 SQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHGSEERTCLANG 2931
+P C + C +P T + SRQ S + + VRY C + Y + G EE CL NG
Sbjct: 1040 -RPTCRDTS---CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NG 1094
Query: 2932 SWTGRQPECK--AVQCGNPGTTANGKV--FRIDGTTFSSSVIYSCMEGYILSGPSVRQCT 2987
+WT P+CK +CG P NG + F + +SSV Y C Y L G C
Sbjct: 1095 NWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC- 1152
Query: 2988 ANGTWSGTLPNCTIISCGDPGIPAN---GLRYGDDYVV----GQNVSYMCQPGYTMELNG 3040
NG WS P C I N LR+ + G++V ++C+ GY +
Sbjct: 1153 RNGQWSEP-PKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRS 1211
Query: 3041 SRIRTCTINGTWSGVM--PTC 3059
+RT W G + PTC
Sbjct: 1212 HTLRTT----CWDGKLEYPTC 1228
Score = 149 bits (375), Expect = 6e-35
Identities = 156/580 (26%), Positives = 239/580 (41%), Gaps = 70/580 (12%)
Query: 2758 MCKVVNCSDPGIPANSKRESKIEHGNF---TY--GTVVFYDCNPGYFLFGSSVLICQPNG 2812
+C +C++ +P +R ++I G++ TY GT Y C PGY G+ +++C+ G
Sbjct: 15 ICVAEDCNE--LPP--RRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KG 69
Query: 2813 QWD--KPLPECIMIDCGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSS-RTC 2866
+W PL +C CGHPG P + G + +G Y+C LLG+ + R C
Sbjct: 70 EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYREC 129
Query: 2867 QLNGHWSGSQPHCSGDATGTCGDPGTPGHGS------RQESNFRTKSTVRYACDTGYILH 2920
+G W+ P C C P +G + + VR+ C++GY +
Sbjct: 130 DTDG-WTNDIPICE---VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 2921 GSEERTCLANGSWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCMEGY 2976
G EE C +G W+ +P+C + C +P G+ + K+ + F Y C GY
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ----YKCNMGY 241
Query: 2977 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG----LRYGDDYVVGQNVSYMCQP 3032
S CT +G W LP+C SC +P IP NG LR + G ++Y C+
Sbjct: 242 EYSERGDAVCTESG-WR-PLPSCEEKSCDNPYIP-NGDYSPLRI--KHRTGDEITYQCRN 296
Query: 3033 GYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNF-------DWGFS 3085
G+ G+ + CT G W P C C P I +G L N G
Sbjct: 297 GFYPATRGNTAK-CTSTG-WIPA-PRCTLKPCDY-PDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 3086 ISYICSPGYEL---SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQ 3141
SY C +E S+ + C +G WS VP CL K C P + + G+ F+
Sbjct: 353 YSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLRK-CYFPYLENGYNQNHGRKFVQG 409
Query: 3142 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQ 3201
+ +C+ + L + T + + WS +P CI S + + + + +
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENGWS-PTPRCIRVKTCSKSSIDIENGFISESQYTYA 468
Query: 3202 VGSVVQFHCKKGHLLQGSTTR---TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDL 3258
+ ++ CK G++ T TC D WS QP CI SC P
Sbjct: 469 LKEKAKYQCKLGYVTADGETSGSITCGKD-GWSA-QPTCI-KSCDIPVFMNARTKNDFTW 525
Query: 3259 PSHGYTLIYTCQPGF-FLAGGTEHRVCRSDNTWTGKVPIC 3297
TL Y C G+ G T + N W+ +PIC
Sbjct: 526 FKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWS-DLPIC 564
Score = 146 bits (369), Expect = 3e-34
Identities = 202/774 (26%), Positives = 296/774 (38%), Gaps = 94/774 (12%)
Query: 2585 CVVISCGELPTPPN-----GNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2639
CV C ELP N G+ G+ AI+ C G+ +G+ + C G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 2640 ET--RCLAGHCGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGS-SVRICQQDHN 2693
+C CG P G G + Y VY CN G++L+G + R C D
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTD-G 133
Query: 2694 WSGQLPSCVPVSCGHPGSPIYGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKAQCQ 2747
W+ +P C V C +P G+ + ++F V F CN GY ++G + C
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 2748 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKI---EHGNFTYGTVVFYDCNPGYFLFGSS 2804
+ WS P C ++C P + S KI E+ F Y CN GY
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ------YKCNMGYEYSERG 247
Query: 2805 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSC-TGKRSLLGQ 2861
+C +G W +PLP C C +P + PN S K+ G + Y C G
Sbjct: 248 DAVCTESG-W-RPLPSCEEKSCDNPYI-PNGDYSPLRIKHRTGDEITYQCRNGFYPATRG 304
Query: 2862 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFR-------TKSTVRYACD 2914
++ C G W + P C+ C P HG N R Y CD
Sbjct: 305 NTAKCTSTG-WIPA-PRCT---LKPCDYPDIK-HGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 2915 TGYILHGS---EERTCLANGSWTGRQP---ECKAVQCGNPGTTANGKVFRIDGTTFSSSV 2968
+ + C +G W+ P +C N +G+ F + G S+
Sbjct: 359 EHFETPSGSYWDHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRKF-VQG----KSI 412
Query: 2969 IYSCMEGYIL-SGPSVRQCTANGTWSGTLPNC-TIISCGDPGIPANGLRYGDD---YVVG 3023
+C GY L + C NG WS T P C + +C I + Y +
Sbjct: 413 DVACHPGYALPKAQTTVTCMENG-WSPT-PRCIRVKTCSKSSIDIENGFISESQYTYALK 470
Query: 3024 QNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG--TNF 3080
+ Y C+ GY T + S TC +G WS PTC + P N R + T F
Sbjct: 471 EKAKYQCKLGYVTADGETSGSITCGKDG-WS-AQPTC--IKSCDIPVFMNARTKNDFTWF 526
Query: 3081 DWGFSISYICSPGYEL---SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKS 3137
++ Y C GYE S + C NG WS ++P C + C P I + K
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELPKIDVHLVPDRKK 584
Query: 3138 FIYQ--SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN 3195
Y+ + FSC F +VG ++ C G S P C E Q SC P +G+
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQ-SCGPPPELLNGNVK 642
Query: 3196 NTFGFQVG--SVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETP-AHAN 3252
+ G VV+++C L++G C+ D W+ + P CI + P
Sbjct: 643 EKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTTL-PVCIVEESTCGDIPELEHG 700
Query: 3253 VVGMDLPSHGY--TLIYTCQPGFFLAGGTEHR-VCRSDNTWTGKVPICEAGSKI 3303
+ P + Y ++ + C F + G HR + WT ++P C A K+
Sbjct: 701 WAQLSSPPYYYGDSVEFNCSESFTMIG---HRSITCIHGVWT-QLPQCVAIDKL 750
Score = 100 bits (248), Expect = 3e-20
Identities = 140/622 (22%), Positives = 231/622 (37%), Gaps = 105/622 (16%)
Query: 2287 QLRVCQPPPPVPNAEILTED-DEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAP 2345
Q++ C PPP + N + + +E+ +++ Y C P F + G + C GE +
Sbjct: 626 QVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTL---- 681
Query: 2346 PVCQV---LCPANELRLDSTGVILSPG--YPDS-----------------------YPNL 2377
PVC V C + SP Y DS + L
Sbjct: 682 PVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQL 741
Query: 2378 QMCAWSISVE--KGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNIT 2435
C ++ K N+ + E + +KEFD S + G +
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFD---------HNSNIRYRCRGKEGWIHTVC 792
Query: 2436 SNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQT----GGQLNSVVRWA 2491
NG +W + + ++ C P P+ + ++ T G+ SV+
Sbjct: 793 ING-----RWDPEVNCSMAQIQL------CPPPPQIPNSHNMTTTLNYRDGEKVSVL--- 838
Query: 2492 CDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC-QAISCGIPKAPTNGGILTT-----DYL 2545
C + + C+ W + +P C + I C P +G I ++ Y
Sbjct: 839 CQENYLIQEGEEITCKDG-----RWQS-IPLCVEKIPCSQPPQIEHGTINSSRSSQESYA 892
Query: 2546 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNG--NKIG 2603
GT+++Y C G+R+S + TT G WS+ P+C + C P +G +
Sbjct: 893 HGTKLSYTCEGGFRISEENETTCYM---GKWSS---PPQCEGLPCKSPPEISHGVVAHMS 946
Query: 2604 TQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN 2663
YG + C GF + G A+ +CL WS + C+ C N +GE
Sbjct: 947 DSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWSHPPS-CIKTDCLSLPSFENAIPMGEK 1004
Query: 2664 ---YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP----GSPIYGR 2716
Y + V Y C +++ G+S C + W+G+ P+C SC +P + I R
Sbjct: 1005 KDVYKAGEQVTYTCATYYKMDGASNVTC-INSRWTGR-PTCRDTSCVNPPTVQNAYIVSR 1062
Query: 2717 TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRE 2776
+ + V + C Y M G + C N W+ PP P P ++
Sbjct: 1063 QMSK-YPSGERVRYQCRSPYEMFGDEEVMC-LNGNWTEPPQCKDSTGKCGPPPPIDNGDI 1120
Query: 2777 SKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAV 2836
+ + + V Y C Y L G+ + C+ NGQW +P P+C+ HP V +
Sbjct: 1121 TSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWSEP-PKCL-----HPCVISREI 1173
Query: 2837 LSGEKYTFGSTVH---YSCTGK 2855
+ T YS TG+
Sbjct: 1174 MENYNIALRWTAKQKLYSRTGE 1195
Score = 59.3 bits (142), Expect = 7e-08
Identities = 99/454 (21%), Positives = 166/454 (36%), Gaps = 71/454 (15%)
Query: 2287 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2346
Q+++C PPP +PN+ +T + G+ + C + + +TC+ G + P
Sbjct: 807 QIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSI----P 862
Query: 2347 VCQVLCPANELRLDSTGVILS-----PGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQT 2401
+C P ++ G I S Y C + + T ++ + +
Sbjct: 863 LCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSS 922
Query: 2402 EKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVF------------LQWSADH 2449
+ + L P I V+ +S Y +T E F +WS
Sbjct: 923 PPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPP 982
Query: 2450 GNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKS 2509
K + +F + P + + G Q V + C +++ G S+ C S
Sbjct: 983 SCIKTDC-LSLPSFENAIPMGEKKD--VYKAGEQ----VTYTCATYYKMDGASNVTCINS 1035
Query: 2510 SYGYHAWDAPVPACQAISCGIPKAPTNGGILT---TDYLVGTRVTYFCNDGYRLSSKELT 2566
+ P C+ SC P N I++ + Y G RV Y C Y + E
Sbjct: 1036 RW------TGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDE-- 1087
Query: 2567 TAVCQSDGTWSNHNKTPRC--VVISCGELPTPPNGNKIGTQTSY-------GSTAIFTCD 2617
V +G W+ + P+C CG P PP N G TS+ S+ + C
Sbjct: 1088 -EVMCLNGNWT---EPPQCKDSTGKCG--PPPPIDN--GDITSFPLSVYAPASSVEYQCQ 1139
Query: 2618 LGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYR--------DT 2669
+ L G+ C +G WSE +CL C I I+ I + + ++
Sbjct: 1140 NLYQLEGNKRITC-RNGQWSE-PPKCL-HPCVISREIMENYNIALRWTAKQKLYSRTGES 1196
Query: 2670 VVYQCNPGFRLIGSSVRICQQDHNWSGQL--PSC 2701
V + C G+RL S + + W G+L P+C
Sbjct: 1197 VEFVCKRGYRLSSRSHTL--RTTCWDGKLEYPTC 1228
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 3203 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP--ECIPHSCKQP-ETPAHA-NVVGMDL 3258
G+ + C+ G+ G+ C W + P +C C P +TP + G ++
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVCRKG-EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNV 103
Query: 3259 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3308
+G +YTC G+ L G +R C +D WT +PICE + V P
Sbjct: 104 FEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAP 152
Score = 45.8 bits (107), Expect = 7e-04
Identities = 156/833 (18%), Positives = 275/833 (33%), Gaps = 157/833 (18%)
Query: 1432 NGTRNGDGRE--PGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPP-VCIAPCG-G 1486
NG GR+ G ++ C PGY L + + +TC+ EN W P+P + + C
Sbjct: 396 NGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCM--ENG--WSPTPRCIRVKTCSKS 451
Query: 1487 NLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS 1546
++ +GFI + + + A Y L +++ DG S
Sbjct: 452 SIDIENGFISESQYTY----------ALKEKAKYQCKLGYVTA------------DGETS 489
Query: 1547 NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNG 1606
S G S P I+S + + R+ ++
Sbjct: 490 GSITCGKDGWSAQPTCIKSCDIPVFMNARTKNDFTW------------------------ 525
Query: 1607 TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSE 1666
+KL T+ Y C GY ST I+ G GW+ LP C+
Sbjct: 526 ------FKLNDTLDYECHDGYESNTGSTTGSIVC--GYNGWSD-LPICYER--ECELPKI 574
Query: 1667 GTVLSPNYPKN-YSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLS 1725
L P+ K+ Y VG +S V + L + + Q
Sbjct: 575 DVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPP 634
Query: 1726 SLSGSHSGESLPLSSGNQITI------RFTSVGPITAKGFHFVYQAVPR--TSSTQCSSV 1777
L + E G+ + RF GP + + +P + C +
Sbjct: 635 ELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDI 694
Query: 1778 PEPRFG--RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPC 1835
PE G + + G SV F+C+ + + G +I C W LP C+
Sbjct: 695 PELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-----GVWTQ-LPQCVAID 748
Query: 1836 GGILTKRKGTILSPGY---PEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1892
K I+ + + +D+N N ++ EG + + WD
Sbjct: 749 KLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEG-----WIHTVCINGRWDP---- 799
Query: 1893 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAA----------------GF 1936
+ N P + NS + LN++ VS
Sbjct: 800 ---EVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDG 856
Query: 1937 HLEYTAIGLDSCPEPQTP-------SSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCM 1989
+ + ++ P Q P +S + Y G +S+ C+ G+ + + TC
Sbjct: 857 RWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 1990 PGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQF 2049
G +W+ P C GV+ Y + T GFG+
Sbjct: 917 MG---KWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEV----TYKCFEGFGIDGPA 969
Query: 2050 VN--FSTETIHDYLEVRSG-----SSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2102
+ + H +++ S E + +G + + T+ + Y+ D +
Sbjct: 970 IAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKK--DVYKAGEQVTYTCATYYKMDGA 1027
Query: 2103 QNKQGFHIVYQAYQL---QSCPDPRPFRNGFVIGND---FTVGQTISFECFPGYTLIGNS 2156
N + + SC +P +N +++ + G+ + ++C Y + G+
Sbjct: 1028 SNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDE 1087
Query: 2157 ALTCLHGVSRNWNHPLPRCE---ALCG-------GNITAMNGTIYSPGYPDEY 2199
+ CL+G NW P P+C+ CG G+IT+ ++Y+P EY
Sbjct: 1088 EVMCLNG---NWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEY 1136
Score = 42.4 bits (98), Expect = 0.008
Identities = 44/156 (28%), Positives = 58/156 (37%), Gaps = 14/156 (8%)
Query: 174 QSSSCGNPGVPPKGVLY---GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
Q CG+PG P G G F+ G K Y+C GY L G +T W
Sbjct: 81 QKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTN 136
Query: 231 PVPICRAEDACGGTMRGSSGIISSPSFPN-EYHNNAD----CTWTIVAEPGDTISLIFTD 285
+PIC T + I+SS P+ EYH C E + +
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 286 FQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKN 321
F +EK +EI P I +G I II +N
Sbjct: 197 FWSKEKPKCVEISCKSPDVI--NGSPISQKIIYKEN 230
Score = 41.6 bits (96), Expect = 0.014
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 2291 CQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE 2337
C PP N EILT D + G Y+C PG+ +GN I+ CR GE
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGE 70
Score = 39.7 bits (91), Expect = 0.054
Identities = 51/253 (20%), Positives = 98/253 (38%), Gaps = 37/253 (14%)
Query: 1948 CPEPQTPSSGI--KIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
C P S G+ + D Y G+ V+++C +G+ + G + C+ +W++P P C+
Sbjct: 931 CKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLG---EKWSHP-PSCIK 986
Query: 2006 QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINL--PIGFGVHLQFVNF---STETIHDY 2060
++ F I Y + T+T + ++ +N T D
Sbjct: 987 TDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDT 1046
Query: 2061 LEVRSGSSETSTVIGRL-----SGPQI------PSSLFSTTHETSLYFHSDYSQNKQGFH 2109
V + + + ++ R SG ++ P +F E + + ++++ Q
Sbjct: 1047 SCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD--EEVMCLNGNWTEPPQCKD 1104
Query: 2110 IVYQAYQLQSCPDPRPFRNGFVIGNDFTV---GQTISFECFPGYTLIGNSALTCLHGVSR 2166
C P P NG + +V ++ ++C Y L GN +TC +G
Sbjct: 1105 ------STGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNG--- 1155
Query: 2167 NWNHPLPRCEALC 2179
W+ P P+C C
Sbjct: 1156 QWSEP-PKCLHPC 1167
Score = 39.3 bits (90), Expect = 0.070
Identities = 54/246 (21%), Positives = 95/246 (38%), Gaps = 46/246 (18%)
Query: 2133 GNDFTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRC---EALCGGNITAMNG 2188
G F G++I C PGY L + +TC+ W+ P PRC + +I NG
Sbjct: 403 GRKFVQGKSIDVACHPGYALPKAQTTVTCMEN---GWS-PTPRCIRVKTCSKSSIDIENG 458
Query: 2189 TIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQ 2248
I Y + ++ + + E DG I
Sbjct: 459 FISESQYT----------YALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKS 508
Query: 2249 ------FSGNTALESVYSTSNQIL-IKFHSDF-----TTSGFFVLSYHAYQ-LRVC-QPP 2294
+ T + + N L + H + +T+G V Y+ + L +C +
Sbjct: 509 CDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERE 568
Query: 2295 PPVPNAEI-LTED---DEFEIGDIIRYQCLPGFTLVG-NAILTCRLG---------ERLQ 2340
+P ++ L D D++++G+++++ C PGFT+VG N++ G E++Q
Sbjct: 569 CELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQ 628
Query: 2341 MDGAPP 2346
G PP
Sbjct: 629 SCGPPP 634
Score = 38.5 bits (88), Expect = 0.12
Identities = 57/273 (20%), Positives = 97/273 (35%), Gaps = 28/273 (10%)
Query: 1727 LSGSHSGESLPLSSGNQITIR----FTSVGPITA---KGFHFVYQAVPRTSSTQCSSVPE 1779
L+GS S ++ P G Q + + S+G + KG + + C +
Sbjct: 33 LTGSWSDQTYP--EGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGD 90
Query: 1780 PRFGRRI---GNEFAVGSSVLFDCNPGYILHGSIAIR-CETVPNSLAQWNDSLPTC-IVP 1834
FG GN F G ++ CN GY L G I R C+T W + +P C +V
Sbjct: 91 TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT-----DGWTNDIPICEVVK 145
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1894
C + G I+S + + + G I+ ++ + S +
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Query: 1895 GDNNAPRLGSYSGTTIPHLLNSTSNNLY---LNFQSDISVSAAGFHLEYTAIGLDSCPEP 1951
+ + +G+ I + N + N + S E L SC E
Sbjct: 206 VEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEK 265
Query: 1952 QTPSSGIKIGD------RYMVGDVVSFQCDQGY 1978
+ I GD ++ GD +++QC G+
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGF 298
Score = 38.1 bits (87), Expect = 0.16
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)
Query: 553 KEIEKESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 609
++ +K CG PG +G + G+ F + C G++L+GE + + + W+ +
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTND 137
Query: 610 IPIC-IFPCLSNFTAP-----MGTVLSPDYPEGYG 638
IPIC + CL TAP + + + PD +G
Sbjct: 138 IPICEVVKCLP-VTAPENGKIVSSAMEPDREYHFG 171
Score = 38.1 bits (87), Expect = 0.16
Identities = 64/286 (22%), Positives = 105/286 (36%), Gaps = 54/286 (18%)
Query: 901 VNTYSCLDPGIPVHG-----RRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHP 955
V C P HG R ++ G+ +S++C+ G+R+S E C W S
Sbjct: 865 VEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSP- 923
Query: 956 LPTCDAL-CGGDVRGPSGTI--LSPGYPEFYPNSLNCTWTVDVTHGKGVQFN-FHTFHLE 1011
P C+ L C G + +S Y +G+ V + F F ++
Sbjct: 924 -PQCEGLPCKSPPEISHGVVAHMSDSY----------------QYGEEVTYKCFEGFGID 966
Query: 1012 DHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGN----FRAQLRFISDFSISYE--- 1064
+ E S + LP NA G ++A + + Y+
Sbjct: 967 GPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDG 1026
Query: 1065 GFNITF--SEYNLEP------CEDPGIPQYG---SRIGFNFGIGDTLTFSCSSGYRLEGT 1113
N+T S + P C +P Q SR + G+ + + C S Y + G
Sbjct: 1027 ASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD 1086
Query: 1114 SEIICLGGGRRVWSAPLPRC---VAECGASATNNEGILLSPNYPLN 1156
E++CL G W+ P P+C +CG + G + S +PL+
Sbjct: 1087 EEVMCLNGN---WTEP-PQCKDSTGKCGPPPPIDNGDITS--FPLS 1126
Score = 37.7 bits (86), Expect = 0.20
Identities = 82/379 (21%), Positives = 133/379 (35%), Gaps = 100/379 (26%)
Query: 980 PEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLA-RLTGSDLP 1038
P PNS N T T++ G+ V +L + + + + PL P
Sbjct: 814 PPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQP 873
Query: 1039 PTINAGLYGNFRA-QLRFISDFSISYE---GFNITFSEYNLE----------------PC 1078
P I G + R+ Q + +SY GF I SE N PC
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRI--SEENETTCYMGKWSSPPQCEGLPC 931
Query: 1079 EDPGIPQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE 1136
+ P +G + + ++ G+ +T+ C G+ ++G + CLG WS P P C+
Sbjct: 932 KSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLG---EKWSHP-PSCIKT 987
Query: 1137 CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGK 1196
S + E + P+ + + +Y +AG+ + + T++ DG
Sbjct: 988 DCLSLPSFENAI-----PMGEKKD---VY----KAGEQVTYTCATYYK--------MDGA 1027
Query: 1197 DKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP 1256
T + +TG T TS C +P
Sbjct: 1028 SNVTCINSRWTGRP----TCRDTS-----------------------------CVNPPTV 1054
Query: 1257 QFGYKISDQ--GHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRF 1314
Q Y +S Q + +G + Y C Y + G + C+ G W P P C
Sbjct: 1055 QNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGN---WTEP-PQC-------- 1102
Query: 1315 KGESSGRILSPGYPFPYDN 1333
+S+G+ G P P DN
Sbjct: 1103 -KDSTGKC---GPPPPIDN 1117
Score = 37.4 bits (85), Expect = 0.27
Identities = 13/39 (33%), Positives = 22/39 (56%)
Query: 921 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
++ G V F C+SGY++ +E + C + +WS P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Score = 37.4 bits (85), Expect = 0.27
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 1094 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
+ G + F C+SGY++EG E+ C G WS P+CV
Sbjct: 168 YHFGQAVRFVCNSGYKIEGDEEMHCSDDG--FWSKEKPKCV 206
Score = 36.6 bits (83), Expect = 0.45
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 5/43 (11%)
Query: 1442 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
P +V +QC Y+L+G +RITC + W PP C+ PC
Sbjct: 1130 PASSVEYQCQNLYQLEGNKRITCRNGQ----WS-EPPKCLHPC 1167
Score = 35.8 bits (81), Expect = 0.77
Identities = 52/234 (22%), Positives = 92/234 (39%), Gaps = 30/234 (12%)
Query: 1263 SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE-CGGRFKGESSGR 1321
SDQ + G+ IY C PGY G+ ++ C GE A + PL C CG
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALN-PLRKCQKRPCGHPGDTPFGTF 96
Query: 1322 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD-------GPPEN 1374
L+ G F Y ++ ++ + + + DT+ + + + + PEN
Sbjct: 97 TLTGGNVFEY--GVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPEN 154
Query: 1375 DMLLKEISGSLIPEGIHSTLNIV--------TIQFDTDFYISKSGF-AIQFSSSVATACR 1425
K +S ++ P+ + V I+ D + + S GF + + V +C+
Sbjct: 155 G---KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK 211
Query: 1426 DPGVPMNGTRNGDG--REPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1477
P V +NG+ + + ++C+ GYE C + W+P P
Sbjct: 212 SPDV-INGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG----WRPLP 260
Score = 35.4 bits (80), Expect = 1.0
Identities = 83/422 (19%), Positives = 147/422 (34%), Gaps = 69/422 (16%)
Query: 1097 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLN 1156
GD++ F+CS + + G I C+ G VW+ LP+CVA + +++ + N
Sbjct: 712 GDSVEFNCSESFTMIGHRSITCIHG---VWT-QLPQCVAIDKLKKCKSSNLIILEEHLKN 767
Query: 1157 ---YENNHECIYSIQVQAG------------KGINISARTFHLAQGDVLKIYDGKDKTTH 1201
+++N Y + + G +N S L +I + + TT
Sbjct: 768 KKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPP-QIPNSHNMTTT 826
Query: 1202 LLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFG-- 1259
L +++ N L ++ + D +Q + E C P + G
Sbjct: 827 L----NYRDGEKVSVLCQENYL-IQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTI 881
Query: 1260 --YKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGE 1317
+ S + + G+ + Y C G+ + + C G+ W P P C
Sbjct: 882 NSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGK---WSSP-PQCEGLPCKSPPEI 937
Query: 1318 SSGRI--LSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP--- 1372
S G + +S Y + + +C +D I + W PP
Sbjct: 938 SHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKC------------LGEKWSHPPSCI 985
Query: 1373 ENDMLLKEISGSLIPEG----IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA------- 1421
+ D L + IP G ++ VT T + + + +S
Sbjct: 986 KTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRD 1045
Query: 1422 TACRDPGVPMNG---TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPP 1478
T+C +P N +R G+ V +QC YE+ G+E + C+ W PP
Sbjct: 1046 TSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGN----W-TEPP 1100
Query: 1479 VC 1480
C
Sbjct: 1101 QC 1102
Score = 35.0 bits (79), Expect = 1.3
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 9/64 (14%)
Query: 1424 CRDPGVPMNGTRNGDGREP------GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1477
C P NG EP G V F C+ GY+++G+E + C + FW
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC---SDDGFWSKEK 202
Query: 1478 PVCI 1481
P C+
Sbjct: 203 PKCV 206
Score = 34.7 bits (78), Expect = 1.7
Identities = 55/256 (21%), Positives = 98/256 (38%), Gaps = 58/256 (22%)
Query: 389 ENG--KRIGSDFSLGSTVQFSCDEDYVLQGAKS-ITCQRIAEVFAAWSDHRPVCKVKTCG 445
ENG + G F G ++ +C Y L A++ +TC WS +VKTC
Sbjct: 395 ENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCME-----NGWSPTPRCIRVKTCS 449
Query: 446 -SNLQGPSGTFTSPNFPFQYDSNA--QCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 502
S++ +G + + + A QC ++ + D E ++T G
Sbjct: 450 KSSIDIENGFISESQYTYALKEKAKYQC-------------KLGYVTADGETS-GSITCG 495
Query: 503 DGGEVGDPRTVLQVLTGSFVPDLIVSMSSQM-----WLHLQ--------------TDESV 543
G P + D+ V M+++ W L T +
Sbjct: 496 KDGWSAQPTCIKSC-------DIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTT 548
Query: 544 GSVGFKVN-YKEIE---KESCGDPGTPLYGI--REGDGFSNRDVLRFECQFGFELIGEKS 597
GS+ N + ++ + C P ++ + R+ D + +VL+F C+ GF ++G S
Sbjct: 549 GSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNS 608
Query: 598 IVCQENNQWSANIPIC 613
+ C S ++PIC
Sbjct: 609 VQCYHFG-LSPDLPIC 623
Score = 34.3 bits (77), Expect = 2.2
Identities = 58/272 (21%), Positives = 94/272 (34%), Gaps = 50/272 (18%)
Query: 1766 VPRTSSTQCSSVPEPRFGRRIGN------EFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1819
+P +C V P G+ + + E+ G +V F CN GY + G + C +
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC----S 193
Query: 1820 SLAQWNDSLPTCI-VPCGGILTKRKGTILSPGYPEP----YDNNLNCVWKITVPEGAGIQ 1874
W+ P C+ + C K + G P Y N +K + G
Sbjct: 194 DDGFWSKEKPKCVEISC-------KSPDVINGSPISQKIIYKENERFQYKCNM--GYEYS 244
Query: 1875 VQVVSFATEHNWDSLDFYDGGDNNAPRL--GSYSGTTIPHLLNSTSNNLYLNFQSDISVS 1932
+ + TE W L + + P + G YS I H T + + ++ +
Sbjct: 245 ERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKH---RTGDEITYQCRNGFYPA 301
Query: 1933 AAGFHLEYTAIG--------LDSCPEPQTPSSGIKIGDR------YMVGDVVSFQCDQGY 1978
G + T+ G L C P G+ + VG S+ CD+ +
Sbjct: 302 TRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHF 361
Query: 1979 SLQGHS---HITCMPGPVRRWNYPIPICLAQC 2007
S HI C W+ +P CL +C
Sbjct: 362 ETPSGSYWDHIHCTQD---GWSPAVP-CLRKC 389
Score = 33.5 bits (75), Expect = 3.8
Identities = 99/480 (20%), Positives = 170/480 (35%), Gaps = 101/480 (21%)
Query: 730 CPDPGIPINARRFGD--NFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
CP P N+ N++ G +SV+C+E ++ +G E ITC DG+ W IP C
Sbjct: 811 CPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE-ITC--KDGR--WQS-IPLC 864
Query: 788 --GAPCGGHFSAPSGVILSP-----GWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTEL 840
PC G I S + K S CE + ++ +
Sbjct: 865 VEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPP 924
Query: 841 NYDVLEVHDGPNL----LSPLLGSYN-GTQVPQFLFSSSNFIYLLFTTDNSRSNN--GFK 893
+ L P + ++ + SY G +V F F D G K
Sbjct: 925 QCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEG-------FGIDGPAIAKCLGEK 977
Query: 894 IHYESVTVNTYSCL-----DPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 948
+ + T CL + IP+ ++ + G V+++C + Y++ + C
Sbjct: 978 WSHPPSCIKT-DCLSLPSFENAIPMGEKK--DVYKAGEQVTYTCATYYKMDGASNVTCIN 1034
Query: 949 NHWWSHPLPTC-DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHT 1007
+ W P TC D C + I+S + YP+ G+ V++ +
Sbjct: 1035 SRWTGRP--TCRDTSCVNPPTVQNAYIVSRQMSK-YPS------------GERVRYQCRS 1079
Query: 1008 FHLEDHHDYLLITENGSFTQP--LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYE 1064
+ E D ++ NG++T+P TG PP I+ G I+ F +S
Sbjct: 1080 PY-EMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNG----------DITSFPLSV- 1127
Query: 1065 GFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR 1124
+ ++ + C + Y+LEG I C G
Sbjct: 1128 -----------------------------YAPASSVEYQCQNLYQLEGNKRITCRNG--- 1155
Query: 1125 VWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL 1184
WS P P+C+ C S E ++ + + S++ +G +S+R+ L
Sbjct: 1156 QWSEP-PKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTL 1214
Score = 33.5 bits (75), Expect = 3.8
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 14/65 (21%)
Query: 582 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 641
+ ++CQ ++L G K I C+ N QWS P C+ PC V+S + E Y N+
Sbjct: 1134 VEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPC----------VISREIMENY--NI 1179
Query: 642 NCIWT 646
WT
Sbjct: 1180 ALRWT 1184
Score = 32.7 bits (73), Expect = 6.5
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%)
Query: 382 CPDPGEPENG--KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
C D E E+G + + G +V+F+C E + + G +SITC + W+ P C
Sbjct: 691 CGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-----IHGVWT-QLPQC 744
Query: 440 ----KVKTCGSN 447
K+K C S+
Sbjct: 745 VAIDKLKKCKSS 756
Score = 32.3 bits (72), Expect = 8.5
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Query: 1612 DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
+Y G V + C++GY ++G + C DDG W++ P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHC--SDDG--FWSKEKPKC 205
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 146 bits (369), Expect = 3e-34
Identities = 107/304 (35%), Positives = 146/304 (48%), Gaps = 29/304 (9%)
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2121 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
RP R G T+G + C PGY L + RCEA CG
Sbjct: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
Query: 2181 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2236
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQLRVCQPPP 2295
G +S G+F G+ E + S N + ++F SD T S F + + + QPP
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPR 712
Query: 2296 PVPN 2299
P+
Sbjct: 713 GRPH 716
Score = 144 bits (364), Expect = 1e-33
Identities = 102/301 (33%), Positives = 142/301 (47%), Gaps = 30/301 (9%)
Query: 1308 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1363
A CGG K + G I SP YP Y + C+W I+V G V L F +F+ E ++D
Sbjct: 433 AICGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1364 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1423
L V DG E+ L+ G P+ I ST + + ++F +D I+K+GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAP 1483
R P G + CDPGYEL ++R C A
Sbjct: 552 SR----PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRR-----------------CEAA 590
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CGG LT +G I SP +P YP +++C W + Y ISL F F E N YDF+
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1599
+ G ++S L G F S+ PE I S N M + F+SD +VS GF + ++ R +
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQP 710
Query: 1600 P 1600
P
Sbjct: 711 P 711
Score = 136 bits (343), Expect = 3e-31
Identities = 92/300 (30%), Positives = 146/300 (48%), Gaps = 32/300 (10%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 1950
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
Query: 1951 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
P ++ + + S++C D GY L P +R C A CG
Sbjct: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
Query: 2009 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2064
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2065 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPR 2124
SG + S + G+ G + P + S + + F SD + +K+GF + + + + PR
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPR 712
Score = 136 bits (343), Expect = 3e-31
Identities = 93/291 (31%), Positives = 140/291 (48%), Gaps = 32/291 (10%)
Query: 617 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLA 672
C + G + SP+YP+ Y + CIW I G + L+F F++E +D+L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 673 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH-NECP 731
V+DG S S ++G + G E P + S S L L+F +D S++ GF + N F +EC
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDECS 552
Query: 732 DPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPC 791
P R G CE+ + T G+ +C D + +C A C
Sbjct: 553 RPN------RGG------------CEQRCLNTLGSYKCSC---DPGYELAPDKRRCEAAC 591
Query: 792 GGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEV 847
GG + +G I SPGWP Y + NC W + A + I + F+ F+TE N YD +EV
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 848 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYES 898
G S L G + G++ P+ + S N + + F +DN+ S GFK H+ S
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 136 bits (342), Expect = 4e-31
Identities = 98/300 (32%), Positives = 143/300 (47%), Gaps = 40/300 (13%)
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1598 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
P R G + + +T+ Y CD GY L P R C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
Query: 1655 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1710
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1711 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVP 1767
VEV G T S L GS E + S N + + F S ++ KGF HF + P
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRP 706
Score = 124 bits (311), Expect = 2e-27
Identities = 84/283 (29%), Positives = 138/283 (48%), Gaps = 29/283 (10%)
Query: 444 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 499
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
Query: 500 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 559
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 619
C P G E + + C G+EL +K C C
Sbjct: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
Query: 620 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 675
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
Query: 676 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 718
G + +S + G F G+E P +TS + +R+EF++D+++S +GF
Sbjct: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 115 bits (288), Expect = 8e-25
Identities = 89/295 (30%), Positives = 128/295 (43%), Gaps = 38/295 (12%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
N G + L + + SC GY L + R E
Sbjct: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 295
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 296 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKK 346
E+ L G P I S N +R+ F +D+ +GF A + +K
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEK 704
Score = 113 bits (283), Expect = 3e-24
Identities = 84/291 (28%), Positives = 132/291 (45%), Gaps = 32/291 (10%)
Query: 789 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 844
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 904
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF +++
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EVD 549
Query: 905 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 964
C P G + + SCD GY L+ ++ C+A CG
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 965 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLIT 1020
G + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 1021 ENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITF 1070
+ L + GS+ P I + Y N R + F SD ++S +GF F
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHF 700
Score = 113 bits (282), Expect = 4e-24
Identities = 84/294 (28%), Positives = 128/294 (43%), Gaps = 35/294 (11%)
Query: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1710
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1771 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
S E R +G S C+PGY E P+
Sbjct: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
Query: 1831 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1886
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY 1940
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 105 bits (262), Expect = 8e-22
Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 34/295 (11%)
Query: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
++ C P R G + SC GY L RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
+ G + L G F G S + ++S N + +EF SD + +GF+ + S
Sbjct: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 100 bits (250), Expect = 2e-20
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2289
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
Query: 2290 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
C P +CL +G+ +C G L D C+
Sbjct: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
Query: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2405
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 2406 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 85.1 bits (209), Expect = 1e-15
Identities = 91/327 (27%), Positives = 131/327 (40%), Gaps = 70/327 (21%)
Query: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 293
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 294 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
YLE+ SE T+ G P I S + L L FV+D + GF+ + K +D
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Query: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
SR N GG C + +LGS + SCD
Sbjct: 550 ECSRP----------------NRGG---CEQRCLN--------------TLGS-YKCSCD 575
Query: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Y L K C+ CG L +G+ TSP +P +Y N
Sbjct: 576 PGYELAPDKR-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKN 616
Query: 470 CVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDL 525
C+W + A T I + F+ F+ E G D D EV T L G F P++
Sbjct: 617 CIWQLVA-PTQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEV 673
Query: 526 IVSMSSQMWLHLQTDESVGSVGFKVNY 552
I S + M + ++D +V GFK ++
Sbjct: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 73.9 bits (180), Expect = 3e-12
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 13/120 (10%)
Query: 626 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 681
G SP+YP GY +++C+W I PG +I L+F DL +D++ V+DG ++
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 682 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT---------FGHNECPD 732
P+ G F G+++P + S L +EF++ + G+GF Y +GH + P+
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPN 450
Score = 70.5 bits (171), Expect = 3e-11
Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 120
CGG L LNG+I SPG+P YP NC W ++A + RI + F F E +YD++
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
+ G + + G P +TS + + SD VS GFK ++ + +
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPAL-- 708
Query: 181 PGVPPKGVLYGTRFDVGDKIR 201
PP+G + +F V + R
Sbjct: 709 --QPPRGRPHQLKFRVQKRNR 727
Score = 67.4 bits (163), Expect = 2e-10
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2281
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 62.8 bits (151), Expect = 6e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 387 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 434
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
Query: 435 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 493
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
Query: 494 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
Query: 551 NYKEIEKESCGDPGTPLYG 569
Y+ I CG YG
Sbjct: 430 VYEAI----CGGDVKKDYG 444
Score = 62.4 bits (150), Expect = 8e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 59.7 bits (143), Expect = 5e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2418
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
Query: 2419 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2476
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
Query: 2477 ISQTGGQLNSVVRWACDRGFRL 2498
+ L S + +CD G+ L
Sbjct: 560 EQRCLNTLGS-YKCSCDPGYEL 580
Score = 58.5 bits (140), Expect = 1e-07
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 889 NNGFKIHYESV 899
GF YE++
Sbjct: 424 GKGFFAVYEAI 434
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1187
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1188 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Query: 1245 F-------ELSHCEDPGIP 1256
+ H + P P
Sbjct: 434 ICGGDVKKDYGHIQSPNYP 452
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
Query: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1764 QAV 1766
+A+
Sbjct: 432 EAI 434
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1361 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1414
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 963 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1018
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1019 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1056
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Score = 38.9 bits (89), Expect = 0.091
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
Query: 2467 TPESPPHGYIIS 2478
+G+I S
Sbjct: 437 GDVKKDYGHIQS 448
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 145 bits (367), Expect = 5e-34
Identities = 102/280 (36%), Positives = 137/280 (48%), Gaps = 28/280 (10%)
Query: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
A CGG + G I SP +P +Y S C W I + GF V L F +F E +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2120
LEVR G SE+ST+IGR G + P + ST+ L F SD S NK GF + + ++ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2121 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2180
RP R G T+G + C PGY L + RCEA CG
Sbjct: 552 S--RPNRGGCEQRCLNTLG-SYKCSCDPGYELAPDKR----------------RCEAACG 592
Query: 2181 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2236
G +T +NG+I SPG+P EYP ++C W + P I + F +TE YDF+ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2237 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2276
G +S G+F G+ E + S N + ++F SD T S
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVS 692
Score = 144 bits (362), Expect = 2e-33
Identities = 105/310 (33%), Positives = 146/310 (47%), Gaps = 31/310 (10%)
Query: 1308 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1363
A CGG K + G I SP YP Y + C+W I+V G V L F +F+ E ++D
Sbjct: 433 AICGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1364 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1423
L V DG E+ L+ G P+ I ST + + ++F +D I+K+GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAP 1483
R P G + CDPGYEL ++R C A
Sbjct: 552 SR----PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRR-----------------CEAA 590
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CGG LT +G I SP +P YP +++C W + Y ISL F F E N YDF+
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1599
+ G ++S L G F S+ PE I S N M + F+SD +VS GF + + L E D
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVL-EGAGD 709
Query: 1600 PGNIMNGTRL 1609
+ ++G L
Sbjct: 710 RHSHLSGLEL 719
Score = 138 bits (347), Expect = 1e-31
Identities = 94/292 (32%), Positives = 141/292 (48%), Gaps = 32/292 (10%)
Query: 617 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLA 672
C + G + SP+YP+ Y + CIW I G + L+F F++E +D+L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 673 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH-NECP 731
V+DG S S ++G + G E P + S S L L+F +D S++ GF + N F +EC
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDECS 552
Query: 732 DPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPC 791
P R G CE+ + T G+ +C D + +C A C
Sbjct: 553 RPN------RGG------------CEQRCLNTLGSYKCSC---DPGYELAPDKRRCEAAC 591
Query: 792 GGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEV 847
GG + +G I SPGWP Y + NC W + A + I + F+ F+TE N YD +EV
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 848 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV 899
G S L G + G++ P+ + S N + + F +DN+ S GFK H+ SV
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSV 703
Score = 135 bits (341), Expect = 5e-31
Identities = 90/284 (31%), Positives = 140/284 (49%), Gaps = 32/284 (11%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
CGG + K G I SP YP+ Y + C+W+I V EG + + SF E + +D L+
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPE 1950
DG ++ +G Y G P + STS+ L+L F SD S++ AGF + + +D C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSR 553
Query: 1951 PQTPSSGIKIGDRYMVGDVVSFQC--DQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
P ++ + + S++C D GY L P +R C A CG
Sbjct: 554 PNRGGC-----EQRCLNTLGSYKCSCDPGYEL----------APDKRR------CEAACG 592
Query: 2009 GAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIHDYLEVR 2064
G ++ +G I SPG+P YP + +C W + P + + LQF F TE +D++EVR
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2065 SGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 2108
SG + S + G+ G + P + S + + F SD + +K+GF
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 135 bits (340), Expect = 7e-31
Identities = 97/294 (32%), Positives = 141/294 (47%), Gaps = 40/294 (13%)
Query: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
A CGG++ G I SPN+P Y S+ C W I V+ + + L F SF IE + YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
L + DG +S LIG + + P+ I+S+S+ + L F SDGS++ GF + + ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1598 FDPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
P R G + + +T+ Y CD GY L P R C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYELA--------------PDKRR----C 587
Query: 1655 HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV---- 1710
A CG T G++ SP +PK Y NC++ + P ++ + QF FF+T +DV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1711 -VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HF 1761
VEV G T S L GS E + S N + + F S ++ KGF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 124 bits (311), Expect = 2e-27
Identities = 84/283 (29%), Positives = 138/283 (48%), Gaps = 29/283 (10%)
Query: 444 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTL 499
CG +++ G SPN+P Y + C+W I V+ + + F+ F++E YD L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDYL 493
Query: 500 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 559
+ DG + T++ G PD I S SS++WL +D S+ GF VN+ + E +
Sbjct: 494 EVRDGHS--ESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLS 619
C P G E + + C G+EL +K C C
Sbjct: 551 CSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR--------------CEAACGG 593
Query: 620 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAVKD 675
T G++ SP +P+ Y N NCIW +++ RI L F+ F+ E ++DF+ V+
Sbjct: 594 FLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRS 653
Query: 676 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 718
G + +S + G F G+E P +TS + +R+EF++D+++S +GF
Sbjct: 654 GLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 115 bits (288), Expect = 8e-25
Identities = 87/314 (27%), Positives = 139/314 (44%), Gaps = 36/314 (11%)
Query: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHD-----V 1710
A CG G + SPNYP +Y C++ I V + F V F F+ HD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1711 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1770
+EV DG ++ S+L+ G + + S+ +++ ++F S G I GF +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1771 STQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
S E R +G S C+PGY E P+
Sbjct: 552 SRPNRGGCEQRCLNTLG-------SYKCSCDPGY----------ELAPDKRR-------- 586
Query: 1831 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----W 1886
C CGG LTK G+I SPG+P+ Y N NC+W++ P I +Q F TE N +
Sbjct: 587 CEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946
D ++ G ++ G + G+ P ++ S NN+ + F+SD +VS GF + ++ L+
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSV-LE 705
Query: 1947 SCPEPQTPSSGIKI 1960
+ + SG+++
Sbjct: 706 GAGDRHSHLSGLEL 719
Score = 115 bits (287), Expect = 1e-24
Identities = 88/291 (30%), Positives = 126/291 (43%), Gaps = 38/291 (13%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CGG +K G I+SP +P Y C W I E + + FQSF +E YDYL
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
+ DGH + R G+ P + ST S L+ SD +++ GF V +++E+ S
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
N G + L + + SC GY L + R E
Sbjct: 555 NRGGCEQRCL-----NTLGSYKCSCDPGYELAPDKR--------------------RCEA 589
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYL 295
ACGG + +G I+SP +P EY N +C W +VA ISL F F+ E KYD++
Sbjct: 590 ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 296 EIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
E+ L G P I S N +R+ F +D+ +GF A +
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 113 bits (283), Expect = 3e-24
Identities = 84/291 (28%), Positives = 132/291 (45%), Gaps = 32/291 (10%)
Query: 789 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 844
A CGG G I SP +P Y+ S C W I+ G + +TF+ F+ E + YD
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 904
LEV DG + S L+G Y G + P + S+S+ ++L F +D S + GF +++
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EVD 549
Query: 905 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 964
C P G + + SCD GY L+ ++ C+A CG
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 965 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLIT 1020
G + +G+I SPG+P+ YP + NC W + + F F E + +D++ +
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 1021 ENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITF 1070
+ L + GS+ P I + Y N R + F SD ++S +GF F
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITS-QYNNMRVE--FKSDNTVSKKGFKAHF 700
Score = 105 bits (262), Expect = 8e-22
Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 34/295 (11%)
Query: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
+A+CGGDV+ G I SP YP+ Y S C W + V+ G V F +F +E H +D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
YL + + S + L R G + P I + + R L+F+SD SI+ GF + F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
++ C P R G + SC GY L RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
A CG T G + SP +P Y N CI+ + I++ F DV K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
+ G + L G F G S + ++S N + +EF SD + +GF+ + S
Sbjct: 649 VEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 100 bits (250), Expect = 2e-20
Identities = 79/297 (26%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
EA+CGG++ G I SP YPD+Y + C W ++V G + + F + E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2289
++ V DG ++S IG++ G + + STS+++ +KF SD +GF V + ++
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK--EVD 549
Query: 2290 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
C P +CL +G+ +C G L D C+
Sbjct: 550 ECSRPN----------------RGGCEQRCL---NTLGSYKCSCDPGYELAPDKRR--CE 588
Query: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EF 2405
C +L+ G I SPG+P YP + C W + Y I++ +FF+TE ++
Sbjct: 589 AACGGFLTKLN--GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 646
Query: 2406 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
D ++V G S + G ITS + + +++ +D+ +KKGF+ + +
Sbjct: 647 DFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 88.2 bits (217), Expect = 1e-16
Identities = 96/345 (27%), Positives = 139/345 (40%), Gaps = 71/345 (20%)
Query: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 293
E CGG ++ G I SP++P++Y + C W I G + L F F++E YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 294 YLEIEG--SEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
YLE+ SE T+ G P I S + L L FV+D + GF+ + K +D
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Query: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
SR N GG C + +LGS + SCD
Sbjct: 550 ECSRP----------------NRGG---CEQRCLN--------------TLGS-YKCSCD 575
Query: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Y L K C+ CG L +G+ TSP +P +Y N
Sbjct: 576 PGYELAPDKR-RCE------------------AACGGFLTKLNGSITSPGWPKEYPPNKN 616
Query: 470 CVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFV----PDL 525
C+W + A T I + F+ F+ E G D D EV T L G F P++
Sbjct: 617 CIWQLVA-PTQYRISLQFDFFETE-GNDVCKY-DFVEVRSGLTADSKLHGKFCGSEKPEV 673
Query: 526 IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGI 570
I S + M + ++D +V GFK ++ + E GD + L G+
Sbjct: 674 ITSQYNNMRVEFKSDNTVSKKGFKAHFFSV-LEGAGDRHSHLSGL 717
Score = 73.9 bits (180), Expect = 3e-12
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 13/120 (10%)
Query: 626 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 681
G SP+YP GY +++C+W I PG +I L+F DL +D++ V+DG ++
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 682 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT---------FGHNECPD 732
P+ G F G+++P + S L +EF++ + G+GF Y +GH + P+
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPN 450
Score = 67.4 bits (163), Expect = 2e-10
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
ACG T++ S+G SSP +PN Y + C W I PG+ I L FT + YDY+
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
E+ P G +P PI+S + L + F + SN +GF A Y+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
L +C A CG + G SP YP+ Y C W + V PG I +NFT L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFFVL 2281
YD++ V DG + +P G+F G+ E + ST +++ ++F S++ GFF +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 62.8 bits (151), Expect = 6e-09
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 387 EPENGKRIGSDFSLGSTVQFSCDE------------DYVLQGAKSITCQRIAEVFAAWSD 434
EP+ + +G + S + ++ + Y + G K QR +
Sbjct: 253 EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQ 312
Query: 435 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE- 493
R + K CG LQ +G F+SP +P Y ++ CVW I+ K+I +NF DL
Sbjct: 313 ARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII-LNFTSLDLYR 371
Query: 494 ---IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
YD + + DG P + GS +P+ IVS S++W+ ++ + GF
Sbjct: 372 SRLCWYDYVEVRDGFWRKAP--LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFA 429
Query: 551 NYKEIEKESCGDPGTPLYG 569
Y+ I CG YG
Sbjct: 430 VYEAI----CGGDVKKDYG 444
Score = 62.4 bits (150), Expect = 8e-09
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
CG L S+G SP +P+ Y C W I+V I L F S + + YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKA 1591
+ DG +PL G F SKLPE I S+ + + + FRS + GF Y+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1890
CG L G SP YP Y +++CVW+I+V G I + S + +D ++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1891 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
DG AP G + G+ +P + ST + L++ F+S + GF Y AI
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
CG + D +G SP +P Y + + C W I++ G + L F + S +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
VR G + + GR G ++P + ST + F S + +GF VY+A
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 59.7 bits (143), Expect = 5e-08
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQS 2418
G I SP YPD Y ++C W I V +G+++ + + F+ E+ +D L+V DG + +S
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG-HSES 502
Query: 2419 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI--AFYCSTPESPPHGYI 2476
LI Y +I S ++L++ +D NK GF + + CS P G
Sbjct: 503 STLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN---RGGC 559
Query: 2477 ISQTGGQLNSVVRWACDRGFRL 2498
+ L S + +CD G+ L
Sbjct: 560 EQRCLNTLGS-YKCSCDPGYEL 580
Score = 58.5 bits (140), Expect = 1e-07
Identities = 37/131 (28%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
L G + + + KC A CG +G SP +P Y ++C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
F + +++ L YD +EV DG +PL G + G+++P+ + S+ + +++ F + ++
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 889 NNGFKIHYESV 899
GF YE++
Sbjct: 424 GKGFFAVYEAI 434
Score = 57.0 bits (136), Expect = 3e-07
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1187
L +C A CG + ++ G SP YP Y + C++ I V G+ I ++ + L +
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1188 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
D +++ DG + L G F G+ + + ST ++LW+EF S + +GF VY +
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPE-PIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Query: 1245 F-------ELSHCEDPGIP 1256
+ H + P P
Sbjct: 434 ICGGDVKKDYGHIQSPNYP 452
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Query: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
R L C A CG S G SP YP YS +CV+ I+V P E ++ F +++
Sbjct: 314 RKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRS 372
Query: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
L +D VEV DG +++ L GS E + +S+ +++ + F S KGF VY
Sbjct: 373 RLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1764 QAV 1766
+A+
Sbjct: 432 EAI 434
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
Y P+C G +S+G SP YP Y ++ C+W I V PG + L F + D
Sbjct: 317 YKCPAC-----GETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1361 S----HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQF-DTDFYISKSGFAI 1414
S +D + V DG L GS +PE I ST + + ++F + ++ K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 963 CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLL 1018
CG ++ +G SP YP Y ++C W + VT G+ + NF + L +DY+
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1019 ITENGSFTQPL-ARLTGSDLPPTI---NAGLYGNFRAQLRFI 1056
+ + PL R GS LP I ++ L+ FR+ ++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Score = 38.9 bits (89), Expect = 0.091
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 7/132 (5%)
Query: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
CPA E DSTG SP YP+ Y C W ISV G I + + +D
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
++V DG ++P+ G I S +++++ + KGF Y A C
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI-CG 436
Query: 2467 TPESPPHGYIIS 2478
+G+I S
Sbjct: 437 GDVKKDYGHIQS 448
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 134 bits (337), Expect = 2e-30
Identities = 128/460 (27%), Positives = 198/460 (43%), Gaps = 62/460 (13%)
Query: 2758 MCKVVNCSDPGIPANSKRESKIEHGNF---TY--GTVVFYDCNPGYFLFGSSVLICQPNG 2812
+C +C++ +P +R ++I G++ TY GT Y C PGY G+ +++C+ G
Sbjct: 15 ICVAEDCNE--LPP--RRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KG 69
Query: 2813 QWD--KPLPECIMIDCGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSS-RTC 2866
+W PL +C CGHPG P + G + +G Y+C LLG+ + R C
Sbjct: 70 EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYREC 129
Query: 2867 QLNGHWSGSQPHCSGDATGTCGDPGTPGHGS------RQESNFRTKSTVRYACDTGYILH 2920
+G W+ P C C P +G + + VR+ C++GY +
Sbjct: 130 DTDG-WTNDIPICE---VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 2921 GSEERTCLANGSWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCMEGY 2976
G EE C +G W+ +P+C + C +P G+ + K+ + F Y C GY
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ----YKCNMGY 241
Query: 2977 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG----LRYGDDYVVGQNVSYMCQP 3032
S CT +G W LP+C SC +P IP NG LR + G ++Y C+
Sbjct: 242 EYSERGDAVCTESG-WR-PLPSCEEKSCDNPYIP-NGDYSPLRI--KHRTGDEITYQCRN 296
Query: 3033 GYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNF-------DWGFS 3085
G+ G+ + CT G W P C C P I +G L N G
Sbjct: 297 GFYPATRGNTAK-CTSTG-WIPA-PRCTLKPCDY-PDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 3086 ISYICSPGYEL---SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQ 3141
SY C +E S+ + C +G WS VP CL K C P + + G+ F+
Sbjct: 353 YSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLRK-CYFPYLENGYNQNHGRKFVQG 409
Query: 3142 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3181
+ +C+ + L + T + + WS +P CI + T
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENGWS-PTPRCIRVSFT 448
Score = 114 bits (284), Expect = 2e-24
Identities = 118/463 (25%), Positives = 168/463 (36%), Gaps = 81/463 (17%)
Query: 2523 CQAISCGIPKAPTNGGILTTD-----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWS 2577
C A C N ILT Y GT+ Y C GYR S VC+ G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYR--SLGNVIMVCRK-GEWV 72
Query: 2578 NHNKTPRCVVISCGELPTPPNGNKI---GTQTSYGSTAIFTCDLGFMLVGSA-VRECLSS 2633
N +C CG P G G YG A++TC+ G+ L+G REC +
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTD 132
Query: 2634 GLWSESETRCLAGHCGIPELIVNGQVIG------ENYGYRDTVVYQCNPGFRLIGSSVRI 2687
G W+ C C NG+++ Y + V + CN G+++ G
Sbjct: 133 G-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMH 191
Query: 2688 CQQDHNWSGQLPSCVPVSCGHP----GSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK 2743
C D WS + P CV +SC P GSPI + + N+ + CN+GY
Sbjct: 192 CSDDGFWSKEKPKCVEISCKSPDVINGSPISQKII---YKENERFQYKCNMGYEYSERGD 248
Query: 2744 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYF-LFG 2802
A C W P P C+ +C +P IP +I+H G + Y C G++
Sbjct: 249 AVC-TESGW-RPLPSCEEKSCDNPYIPNGDYSPLRIKHRT---GDEITYQCRNGFYPATR 303
Query: 2803 SSVLICQPNGQWDKPLPECIMIDCGHPGV------------PPNAVLSGEKYTFGSTVHY 2850
+ C G W P P C + C +P + P V G+ Y++ H+
Sbjct: 304 GNTAKCTSTG-W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHF 361
Query: 2851 SCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTP------------GHGSR 2898
+W HC+ D P P G+
Sbjct: 362 ETPS--------------GSYW--DHIHCTQDG----WSPAVPCLRKCYFPYLENGYNQN 401
Query: 2899 QESNFRTKSTVRYACDTGYILHGSEER-TCLANGSWTGRQPEC 2940
F ++ AC GY L ++ TC+ NG W+ P C
Sbjct: 402 HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WS-PTPRC 442
Score = 113 bits (283), Expect = 3e-24
Identities = 114/423 (26%), Positives = 170/423 (40%), Gaps = 63/423 (14%)
Query: 2490 WACDRGFRLVGKSSAVCRKSSYGYHAWDA--PVPACQAISCGIPKAPTNGGILTTD---Y 2544
+ C G+R +G VCRK W A P+ CQ CG P G T +
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-----WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 2545 LVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGT 2604
G + Y CN+GY+L E+ C +DG W+ N P C V+ C + P NG + +
Sbjct: 105 EYGVKAVYTCNEGYQLLG-EINYRECDTDG-WT--NDIPICEVVKCLPVTAPENGKIVSS 160
Query: 2605 ------QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQ 2658
+ +G F C+ G+ + G C G WS+ + +C+ C P+ ++NG
Sbjct: 161 AMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPD-VINGS 219
Query: 2659 VIGENYGYRDT--VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSP---- 2712
I + Y++ Y+CN G+ +C + W LPSC SC +P P
Sbjct: 220 PISQKIIYKENERFQYKCNMGYEYSERGDAVCTES-GWR-PLPSCEEKSCDNPYIPNGDY 277
Query: 2713 ----IYGRTSGNGFNFNDVVTFSCNIGY--LMQGPTKAQCQANRQWSHPPPMCKVVNCSD 2766
I RT D +T+ C G+ +G T A+C + W P P C + C
Sbjct: 278 SPLRIKHRT-------GDEITYQCRNGFYPATRGNT-AKC-TSTGWI-PAPRCTLKPCDY 327
Query: 2767 PGIPANSKRESKIEHGNF--TYGTVVFYDCNPGYFLFGSSV---LICQPNGQWDKPLPEC 2821
P I + F G Y C+ + S + C +G W +P C
Sbjct: 328 PDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-C 385
Query: 2822 IMIDCGHP----GVPPNAVLSGEKYTFGSTVHYSC-TGKRSLLGQSSRTCQLNGHWSGSQ 2876
+ C P G N G K+ G ++ +C G Q++ TC NG WS +
Sbjct: 386 LR-KCYFPYLENGYNQN---HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT- 439
Query: 2877 PHC 2879
P C
Sbjct: 440 PRC 442
Score = 102 bits (254), Expect = 7e-21
Identities = 120/456 (26%), Positives = 171/456 (37%), Gaps = 62/456 (13%)
Query: 2585 CVVISCGELPTPPN-----GNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2639
CV C ELP N G+ G+ AI+ C G+ +G+ + C G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 2640 ET--RCLAGHCGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGS-SVRICQQDHN 2693
+C CG P G G + Y VY CN G++L+G + R C D
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTD-G 133
Query: 2694 WSGQLPSCVPVSCGHPGSPIYGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKAQCQ 2747
W+ +P C V C +P G+ + ++F V F CN GY ++G + C
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 2748 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKI---EHGNFTYGTVVFYDCNPGYFLFGSS 2804
+ WS P C ++C P + S KI E+ F Y CN GY
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ------YKCNMGYEYSERG 247
Query: 2805 VLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLS--GEKYTFGSTVHYSC-TGKRSLLGQ 2861
+C +G W +PLP C C +P + PN S K+ G + Y C G
Sbjct: 248 DAVCTESG-W-RPLPSCEEKSCDNPYI-PNGDYSPLRIKHRTGDEITYQCRNGFYPATRG 304
Query: 2862 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFR-------TKSTVRYACD 2914
++ C G W + P C+ C P HG N R Y CD
Sbjct: 305 NTAKCTSTG-WIPA-PRCT---LKPCDYPDIK-HGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 2915 TGYILHGS---EERTCLANGSWTGRQP---ECKAVQCGNPGTTANGKVFRIDGTTFSSSV 2968
+ + C +G W+ P +C N +G+ F + G S+
Sbjct: 359 EHFETPSGSYWDHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRKF-VQG----KSI 412
Query: 2969 IYSCMEGYIL-SGPSVRQCTANGTWSGTLPNCTIIS 3003
+C GY L + C NG WS T P C +S
Sbjct: 413 DVACHPGYALPKAQTTVTCMENG-WSPT-PRCIRVS 446
Score = 100 bits (248), Expect = 3e-20
Identities = 108/417 (25%), Positives = 155/417 (37%), Gaps = 82/417 (19%)
Query: 2896 GSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP--ECKAVQCGNPGTTAN 2953
GS + + + Y C GY G+ C G W P +C+ CG+PG T
Sbjct: 35 GSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVALNPLRKCQKRPCGHPGDTPF 93
Query: 2954 GKVFRIDGTTFSSSV--IYSCMEGYILSGP-SVRQCTANGTWSGTLPNCTIISCGDPGIP 3010
G G F V +Y+C EGY L G + R+C +G W+ +P C ++ C P
Sbjct: 94 GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAP 152
Query: 3011 ANG------LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTC 3064
NG + +Y GQ V ++C GY +E G C+ +G WS P C ++C
Sbjct: 153 ENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE--GDEEMHCSDDGFWSKEKPKCVEISC 210
Query: 3065 PTPPQISNGRL-EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3123
+P I+ + + + Y C+ GYE S C +G W +P C K C
Sbjct: 211 KSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCD 268
Query: 3124 DPGI------PAQGK-REGKSFIYQSEVSF-------------------------SCNFP 3151
+P I P + K R G YQ F C++P
Sbjct: 269 NPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYP 328
Query: 3152 FILVGS-------------------STRICQADGTWSGS---SPHCIE-------PTQTS 3182
I G S + T SGS HC + P
Sbjct: 329 DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRK 388
Query: 3183 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL-QGSTTRTCLPDLTWSGIQPECI 3238
C P + +QN+ F G + C G+ L + TT TC+ + WS P CI
Sbjct: 389 CYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMEN-GWSP-TPRCI 443
Score = 94.7 bits (234), Expect = 1e-18
Identities = 89/352 (25%), Positives = 131/352 (37%), Gaps = 35/352 (9%)
Query: 2966 SSVIYSCMEGYILSGPSVRQCTANGTWSGTLP--NCTIISCGDPGIPANG---LRYGDDY 3020
+ IY C GY G + C G W P C CG PG G L G+ +
Sbjct: 46 TQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 3021 VVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT-- 3078
G Y C GY + L R C +G W+ +P C V C NG++ +
Sbjct: 105 EYGVKAVYTCNEGYQL-LGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAM 162
Query: 3079 ----NFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKRE 3134
+ +G ++ ++C+ GY++ + C +G WS E P+C+ C P + G
Sbjct: 163 EPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDV-INGSPI 221
Query: 3135 GKSFIYQSEVSFS--CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG 3192
+ IY+ F CN + +C G W P C E SC+NP +P
Sbjct: 222 SQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEK---SCDNPYIPNGD 276
Query: 3193 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSG--IQPECIPHSCKQPETP-- 3248
+ G + + C+ G TR T +G P C C P+
Sbjct: 277 YSPLRIKHRTGDEITYQCRNGFY---PATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHG 333
Query: 3249 --AHANVVGMDLP-SHGYTLIYTCQPGFFLAGGT--EHRVCRSDNTWTGKVP 3295
H N+ P + G Y C F G+ +H C D W+ VP
Sbjct: 334 GLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP 384
Score = 80.5 bits (197), Expect = 3e-14
Identities = 96/387 (24%), Positives = 138/387 (35%), Gaps = 53/387 (13%)
Query: 2465 CSTPESPPHGYIISQTGGQLNSVVR--WACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPA 2522
C P P G G V+ + C+ G++L+G+ + W +P
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTNDIPI 140
Query: 2523 CQAISCGIPKAPTNGGILTT------DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2576
C+ + C AP NG I+++ +Y G V + CN GY++ E C DG W
Sbjct: 141 CEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDE--EMHCSDDGFW 198
Query: 2577 SNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIF--TCDLGFMLVGSAVRECLSSG 2634
S + P+CV ISC + P NG+ I + Y F C++G+ C SG
Sbjct: 199 S--KEKPKCVEISC-KSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG 255
Query: 2635 LWSESETRCLAGHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQQDH 2692
W + C C P I NG +R D + YQC GF
Sbjct: 256 -WRPLPS-CEEKSCDNP-YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 2693 NWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIG--YLMQGPTKAQCQANR 2750
W P C C +P G N F +G Y + +
Sbjct: 313 GWI-PAPRCTLKPCDYPDIKHGGLYHENMRR----PYFPVAVGKYYSYYCDEHFETPSGS 367
Query: 2751 QWSHPPPMCKVVNCS----DPGIPANSK-------RESKIEHG-NFTYGTVVFYDCNPGY 2798
W H ++C+ P +P K HG F G + C+PGY
Sbjct: 368 YWDH-------IHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGY 420
Query: 2799 FL-FGSSVLICQPNGQWDKPLPECIMI 2824
L + + C NG W P P CI +
Sbjct: 421 ALPKAQTTVTCMENG-W-SPTPRCIRV 445
Score = 70.5 bits (171), Expect = 3e-11
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 24/259 (9%)
Query: 3059 CRAVTCPTPP-----QISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGE 3113
C A C P +I G + G Y C PGY ++ C G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 3114 VP--QCLPKFCGDPGIPAQGK---REGKSFIYQSEVSFSCNFPFILVGS-STRICQADGT 3167
P +C + CG PG G G F Y + ++CN + L+G + R C DG
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 3168 WSGSSPHCIEPTQTSCENPGVPRHG-----SQNNTFGFQVGSVVQFHCKKGHLLQGSTTR 3222
W+ P C C P +G + + G V+F C G+ ++G
Sbjct: 134 WTNDIPIC---EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 3223 TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR 3282
C D WS +P+C+ SCK P+ + + + Y C G+ + +
Sbjct: 191 HCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGD-A 249
Query: 3283 VCRSDNTWTGKVPICEAGS 3301
VC +++ W +P CE S
Sbjct: 250 VC-TESGWR-PLPSCEEKS 266
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 3203 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP--ECIPHSCKQP-ETPAHA-NVVGMDL 3258
G+ + C+ G+ G+ C W + P +C C P +TP + G ++
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVCRKG-EWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNV 103
Query: 3259 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3308
+G +YTC G+ L G +R C +D WT +PICE + V P
Sbjct: 104 FEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAP 152
Score = 42.4 bits (98), Expect = 0.008
Identities = 44/156 (28%), Positives = 58/156 (37%), Gaps = 14/156 (8%)
Query: 174 QSSSCGNPGVPPKGVLY---GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
Q CG+PG P G G F+ G K Y+C GY L G +T W
Sbjct: 81 QKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINY----RECDTDGWTN 136
Query: 231 PVPICRAEDACGGTMRGSSGIISSPSFPN-EYHNNAD----CTWTIVAEPGDTISLIFTD 285
+PIC T + I+SS P+ EYH C E + +
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 286 FQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKN 321
F +EK +EI P I +G I II +N
Sbjct: 197 FWSKEKPKCVEISCKSPDVI--NGSPISQKIIYKEN 230
Score = 41.6 bits (96), Expect = 0.014
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 2291 CQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGE 2337
C PP N EILT D + G Y+C PG+ +GN I+ CR GE
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGE 70
Score = 38.5 bits (88), Expect = 0.12
Identities = 57/273 (20%), Positives = 97/273 (35%), Gaps = 28/273 (10%)
Query: 1727 LSGSHSGESLPLSSGNQITIR----FTSVGPITA---KGFHFVYQAVPRTSSTQCSSVPE 1779
L+GS S ++ P G Q + + S+G + KG + + C +
Sbjct: 33 LTGSWSDQTYP--EGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGD 90
Query: 1780 PRFGRRI---GNEFAVGSSVLFDCNPGYILHGSIAIR-CETVPNSLAQWNDSLPTC-IVP 1834
FG GN F G ++ CN GY L G I R C+T W + +P C +V
Sbjct: 91 TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT-----DGWTNDIPICEVVK 145
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1894
C + G I+S + + + G I+ ++ + S +
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Query: 1895 GDNNAPRLGSYSGTTIPHLLNSTSNNLY---LNFQSDISVSAAGFHLEYTAIGLDSCPEP 1951
+ + +G+ I + N + N + S E L SC E
Sbjct: 206 VEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEK 265
Query: 1952 QTPSSGIKIGD------RYMVGDVVSFQCDQGY 1978
+ I GD ++ GD +++QC G+
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGF 298
Score = 38.1 bits (87), Expect = 0.16
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)
Query: 553 KEIEKESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSAN 609
++ +K CG PG +G + G+ F + C G++L+GE + + + W+ +
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTND 137
Query: 610 IPIC-IFPCLSNFTAP-----MGTVLSPDYPEGYG 638
IPIC + CL TAP + + + PD +G
Sbjct: 138 IPICEVVKCLP-VTAPENGKIVSSAMEPDREYHFG 171
Score = 37.4 bits (85), Expect = 0.27
Identities = 13/39 (33%), Positives = 22/39 (56%)
Query: 921 DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
++ G V F C+SGY++ +E + C + +WS P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Score = 37.4 bits (85), Expect = 0.27
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 1094 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
+ G + F C+SGY++EG E+ C G WS P+CV
Sbjct: 168 YHFGQAVRFVCNSGYKIEGDEEMHCSDDG--FWSKEKPKCV 206
Score = 35.8 bits (81), Expect = 0.77
Identities = 52/234 (22%), Positives = 92/234 (39%), Gaps = 30/234 (12%)
Query: 1263 SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE-CGGRFKGESSGR 1321
SDQ + G+ IY C PGY G+ ++ C GE A + PL C CG
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALN-PLRKCQKRPCGHPGDTPFGTF 96
Query: 1322 ILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD-------GPPEN 1374
L+ G F Y ++ ++ + + + DT+ + + + + PEN
Sbjct: 97 TLTGGNVFEY--GVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPEN 154
Query: 1375 DMLLKEISGSLIPEGIHSTLNIV--------TIQFDTDFYISKSGF-AIQFSSSVATACR 1425
K +S ++ P+ + V I+ D + + S GF + + V +C+
Sbjct: 155 G---KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK 211
Query: 1426 DPGVPMNGTRNGDG--REPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1477
P V +NG+ + + ++C+ GYE C + W+P P
Sbjct: 212 SPDV-INGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG----WRPLP 260
Score = 35.0 bits (79), Expect = 1.3
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 9/64 (14%)
Query: 1424 CRDPGVPMNGTRNGDGREP------GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1477
C P NG EP G V F C+ GY+++G+E + C + FW
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC---SDDGFWSKEK 202
Query: 1478 PVCI 1481
P C+
Sbjct: 203 PKCV 206
Score = 34.3 bits (77), Expect = 2.2
Identities = 58/272 (21%), Positives = 94/272 (34%), Gaps = 50/272 (18%)
Query: 1766 VPRTSSTQCSSVPEPRFGRRIGN------EFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1819
+P +C V P G+ + + E+ G +V F CN GY + G + C +
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC----S 193
Query: 1820 SLAQWNDSLPTCI-VPCGGILTKRKGTILSPGYPEP----YDNNLNCVWKITVPEGAGIQ 1874
W+ P C+ + C K + G P Y N +K + G
Sbjct: 194 DDGFWSKEKPKCVEISC-------KSPDVINGSPISQKIIYKENERFQYKCNM--GYEYS 244
Query: 1875 VQVVSFATEHNWDSLDFYDGGDNNAPRL--GSYSGTTIPHLLNSTSNNLYLNFQSDISVS 1932
+ + TE W L + + P + G YS I H T + + ++ +
Sbjct: 245 ERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKH---RTGDEITYQCRNGFYPA 301
Query: 1933 AAGFHLEYTAIG--------LDSCPEPQTPSSGIKIGDR------YMVGDVVSFQCDQGY 1978
G + T+ G L C P G+ + VG S+ CD+ +
Sbjct: 302 TRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHF 361
Query: 1979 SLQGHS---HITCMPGPVRRWNYPIPICLAQC 2007
S HI C W+ +P CL +C
Sbjct: 362 ETPSGSYWDHIHCTQD---GWSPAVP-CLRKC 389
Score = 32.3 bits (72), Expect = 8.5
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Query: 1612 DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
+Y G V + C++GY ++G + C DDG W++ P C
Sbjct: 167 EYHFGQAVRFVCNSGYKIEGDEEMHC--SDDG--FWSKEKPKC 205
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 129 bits (324), Expect = 5e-29
Identities = 126/470 (26%), Positives = 194/470 (41%), Gaps = 72/470 (15%)
Query: 2178 LCGGNITAMN--------GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2229
LCG T + G + SPG+P EY N Q+ W + PPG + + FT E
Sbjct: 10 LCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELS 69
Query: 2230 ----YDFITVWDGPDQNSPQIGQFSGNT----ALESVYSTSNQILIKFHSDFTTSGFFV- 2280
YDF+ + G + GQ S +T ++ YS + + I F SD++ F
Sbjct: 70 HLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTG 129
Query: 2281 --LSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGER 2338
Y A + CQ P E T D + C +G +CR G
Sbjct: 130 FEAFYAAEDIDECQVAP----GEAPTCD----------HHC---HNHLGGFYCSCRAGYV 172
Query: 2339 LQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVE 2397
L + C LC + ++ +G + SP YP YP L C +SIS+E+G+++ + FVE
Sbjct: 173 LHRNKR--TCSALC-SGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVE 229
Query: 2398 FFQTEKEFDVLQVYDGPNIQSPVLISLSGDY---SSAFNITSNGHEVFLQWSADHGNNKK 2454
F E + L YD IQ+ G + + I + + V + + D +
Sbjct: 230 SFDVETHPETLCPYDFLKIQTD--REEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHT 287
Query: 2455 GFRIRY--IAFYCSTPESPPHGYIIS-QTGGQLNSVVRWACDRGFRL------VGKSSAV 2505
G++I Y A C P +PP+G++ Q L C+ G+ L + +AV
Sbjct: 288 GWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAV 347
Query: 2506 CRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVT-------YFCNDGY 2558
C+K +WD P+PAC + CG P +G + +Y+ G VT Y C + +
Sbjct: 348 CQKDG----SWDRPMPACSIVDCGPPDDLPSGRV---EYITGPGVTTYKAVIQYSCEETF 400
Query: 2559 RLSSKELTTAVCQSDGTWSN---HNKTPRCVVISCGELPTPPNGNKIGTQ 2605
VC++DG W++ P C + CG G G Q
Sbjct: 401 YTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGRIYGGQ 449
Score = 106 bits (265), Expect = 4e-22
Identities = 100/366 (27%), Positives = 157/366 (42%), Gaps = 52/366 (14%)
Query: 1320 GRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASH----DILRVWDGPPEND 1375
GR+ SPG+P Y N+ W + PG + L F FD E SH D +++ G
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1376 MLLKEISGSLI----PEGIHSTLNIVTIQFDTDFYISK--SGFAIQFSSSVATACR-DPG 1428
L + S + +S + + I F +D+ K +GF +++ C+ PG
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 1429 VPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNL 1488
+ G C GY L +R C A C G +
Sbjct: 148 EAPTCDHHCHNHLGG--FYCSCRAGYVLHRNKR-----------------TCSALCSGQV 188
Query: 1489 -TGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFI-SFSIEPN------YDFLYI 1540
T SG + SP +P PYP C ++I++ + + L F+ SF +E + YDFL I
Sbjct: 189 FTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI 248
Query: 1541 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDP 1600
+ + P G LP RIE+ SNT+ + F +D S +TG+ + Y + C P
Sbjct: 249 QTDREEHGPFCG----KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY-TSTAQPCPYP 303
Query: 1601 GNIMNG--TRLGMDYKLGSTVTYYCDAGY-VLQGY---STLTCIMGDDGRPGWNRALPSC 1654
NG + + Y L + + +C+ GY +LQG+ + T + DG W+R +P+C
Sbjct: 304 MAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDG--SWDRPMPAC 361
Query: 1655 H-APCG 1659
CG
Sbjct: 362 SIVDCG 367
Score = 103 bits (257), Expect = 3e-21
Identities = 103/377 (27%), Positives = 155/377 (41%), Gaps = 55/377 (14%)
Query: 626 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 681
G + SP +P Y N+ WT+ + PG R+ L F FDLE ++DF+ + G +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
Query: 682 PILGTFTGAE------VPSHLT--SNSHILRLEFQADHSMSG--RGFNITYNTFGHNECP 731
+L T G E P T S L + F++D+S GF Y +EC
Sbjct: 84 KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
Query: 732 -DPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAP 790
PG N G S C G++ + T C A
Sbjct: 144 VAPGEAPTCDHHCHNHLGGFYCS--CRAGYVLHRNKRT------------------CSAL 183
Query: 791 CGGH-FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITF-ERFQTELNYDVLEVH 848
C G F+ SG + SP +P Y +C + I E G S+ + F E F E + + L +
Sbjct: 184 CSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPY 243
Query: 849 DGPNLLSPL--LGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 906
D + + G + G +P + + SN + + F TD S + G+KIHY T C
Sbjct: 244 DFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHY---TSTAQPC 300
Query: 907 LDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEE-PL-----LCEKNHWWSHPLPT 958
P P +G + + + S C++GY L PL +C+K+ W P+P
Sbjct: 301 PYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPA 360
Query: 959 CDAL-CGGDVRGPSGTI 974
C + CG PSG +
Sbjct: 361 CSIVDCGPPDDLPSGRV 377
Score = 100 bits (250), Expect = 2e-20
Identities = 93/381 (24%), Positives = 153/381 (40%), Gaps = 51/381 (13%)
Query: 2016 GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH----DYLEVRSGSSETS 2071
G + SPGFPG Y + + WT+ P G+ + L F +F E H D++++ SG+ +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 2072 TVIGRLS--GPQIP--SSLFSTTHETSLYFHSDYSQNK--QGFHIVYQAYQLQSC---PD 2122
T+ G+ S + P + +S + F SDYS K GF Y A + C P
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 2123 PRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGN 2182
P T C + +G +C G + N C ALC G
Sbjct: 148 EAP---------------TCDHHC---HNHLGGFYCSCRAGYVLHRNK--RTCSALCSGQ 187
Query: 2183 I-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV---LQTEP----IYDFIT 2234
+ T +G + SP YP YP C + + + G + ++F ++T P YDF+
Sbjct: 188 VFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLK 247
Query: 2235 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPP 2294
+ +++ P F G T + + SN + I F +D + ++ + C P
Sbjct: 248 IQTDREEHGP----FCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYP 303
Query: 2295 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA----PPVCQV 2350
PN + ++ + D C G+ L+ + Q DG+ P C +
Sbjct: 304 MAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSI 363
Query: 2351 L-C-PANELRLDSTGVILSPG 2369
+ C P ++L I PG
Sbjct: 364 VDCGPPDDLPSGRVEYITGPG 384
Score = 100 bits (248), Expect = 3e-20
Identities = 100/383 (26%), Positives = 166/383 (43%), Gaps = 57/383 (14%)
Query: 787 CGA---PCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN- 841
CG+ P G + P G + SPG+PG Y + W + A PG+ +++ F F EL+
Sbjct: 11 CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
Query: 842 ---YDVLEVHDGPNLLSPLLG--SYNGTQVP--QFLFSSSNFIYLLFTTD--NSRSNNGF 892
YD +++ G +L+ L G S + + P +S + + + F +D N + GF
Sbjct: 71 LCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGF 130
Query: 893 KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 952
+ Y + ++ + PG + H+ G SC +GY L +
Sbjct: 131 EAFYAAEDIDECQ-VAPGEAPTCDHHCHNHLGG--FYCSCRAGYVLHRNK---------- 177
Query: 953 SHPLPTCDALCGGDV-RGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF-HTFHL 1010
TC ALC G V SG + SP YP YP +CT+++ + G V +F +F +
Sbjct: 178 ----RTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDV 233
Query: 1011 EDH------HDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1064
E H +D+L I + P G LP I + + F++D S +
Sbjct: 234 ETHPETLCPYDFLKIQTDREEHGPFC---GKTLPHRIET---KSNTVTITFVTDESGDHT 287
Query: 1065 GFNITFSEYNLEPCEDPGIPQYG--SRIGFNFGIGDTLTFSCSSGYR-LEG-----TSEI 1116
G+ I ++ +PC P P G S + + + D+ + C +GY L+G +
Sbjct: 288 GWKIHYTS-TAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTA 346
Query: 1117 ICLGGGRRVWSAPLPRC-VAECG 1138
+C G W P+P C + +CG
Sbjct: 347 VCQKDGS--WDRPMPACSIVDCG 367
Score = 98.2 bits (243), Expect = 1e-19
Identities = 95/368 (25%), Positives = 150/368 (40%), Gaps = 54/368 (14%)
Query: 1667 GTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSS--LL 1724
G + SP +P Y+ +++ P + + F F L + E YD S +L
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCE-YDFVKLSSGAKVL 86
Query: 1725 SSLSGSHSGES---------LPLSSGNQITIR--FTSVGPITAKGFHFVYQAVPRTSSTQ 1773
++L G S ++ L S IT R +++ P T GF Y A +
Sbjct: 87 ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFT--GFEAFYAA---EDIDE 141
Query: 1774 CSSVP--EPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
C P P N C GY+LH + TC
Sbjct: 142 CQVAPGEAPTCDHHCHNHLG---GFYCSCRAGYVLHRNKR------------------TC 180
Query: 1832 IVPCGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV-SFATEHNWDSL 1889
C G + T+R G + SP YP PY +C + I++ EG + + V SF E + ++L
Sbjct: 181 SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETL 240
Query: 1890 DFYD--GGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDS 1947
YD + G + G T+PH + + SN + + F +D S G+ + YT+
Sbjct: 241 CPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTA-QP 299
Query: 1948 CPEPQTPSSG--IKIGDRYMVGDVVSFQCDQGYS-LQGHSHITCMPGPVRR---WNYPIP 2001
CP P P +G + +Y++ D S C+ GY LQGH + ++ W+ P+P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2002 IC-LAQCG 2008
C + CG
Sbjct: 360 ACSIVDCG 367
Score = 92.0 bits (227), Expect = 9e-18
Identities = 96/362 (26%), Positives = 150/362 (41%), Gaps = 47/362 (12%)
Query: 1844 GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNA 1899
G + SPG+P Y N+ W +T P G +++ F E + +D + G A
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1900 PRLGSYSGTTI----PHLLNSTSNNLYLNFQSDISVSA--AGFHLEYTAIGLDSCPEPQT 1953
G S T S ++L + F+SD S GF Y A +D C Q
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC---QV 144
Query: 1954 PSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM-S 2012
D + + F C +C G V N C A C G + +
Sbjct: 145 APGEAPTCDHHCHNHLGGFYC------------SCRAGYVLHRNKRT--CSALCSGQVFT 190
Query: 2013 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFV-NFSTET------IHDYLEVRS 2065
SG + SP +P YP CT++I+L GF V L FV +F ET +D+L++++
Sbjct: 191 QRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQT 250
Query: 2066 GSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2125
E G G +P + + ++ ++ F +D S + G+ I Y + Q CP P
Sbjct: 251 DREEH----GPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTS-TAQPCPYPMA 305
Query: 2126 FRNGFV--IGNDFTVGQTISFECFPGYTLI-GNSALTCLHGVSR---NWNHPLPRCEAL- 2178
NG V + + + + S C GY L+ G+ L V + +W+ P+P C +
Sbjct: 306 PPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVD 365
Query: 2179 CG 2180
CG
Sbjct: 366 CG 367
Score = 86.3 bits (212), Expect = 5e-16
Identities = 96/365 (26%), Positives = 148/365 (40%), Gaps = 50/365 (13%)
Query: 1146 GILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF-----HLAQGDVLKIYDGKDKTT 1200
G L SP +P Y N+ E +++ G + + F HL + D +K+ G
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1201 HLLGAFTGASMRGL---TLSSTSNQLWLEFNSD--TEGTDEGFQLVYTSFELSHCE-DPG 1254
L G + + R T S + L + F SD E GF+ Y + ++ C+ PG
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 1255 -IPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1313
P + + H G C GY LH + +C A C G+
Sbjct: 148 EAPTCDHHCHN--HLGG--FYCSCRAGYVLHRNKR----------------TCSALCSGQ 187
Query: 1314 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFL-AFDTE------ASHDILR 1366
+ SG + SP YP PY C + I ++ G V L F+ +FD E +D L+
Sbjct: 188 VFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLK 247
Query: 1367 VWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRD 1426
+ E+ G +P I + N VTI F TD +G+ I ++S+ A C
Sbjct: 248 IQTDREEHG----PFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTST-AQPCPY 302
Query: 1427 PGVPMNGTRNGDGRE--PGDTVVFQCDPGYE-LQGE---ERITCIQVENRYFWQPSPPVC 1480
P P NG + + D+ C+ GYE LQG + T + ++ + +P P
Sbjct: 303 PMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACS 362
Query: 1481 IAPCG 1485
I CG
Sbjct: 363 IVDCG 367
Score = 79.0 bits (193), Expect = 8e-14
Identities = 101/372 (27%), Positives = 152/372 (40%), Gaps = 60/372 (16%)
Query: 1493 GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNS 1548
G + SP FP Y + ++ WT+T Y + L F F +E + YDF+ + G +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 1549 PLIGSFQDSKLPERIE------SSSNTMHLAFRSDGSVS--YTGFHLEYKAKLRESCFDP 1600
L G Q+S ER S +++ + FRSD S +TGF Y A+ + C
Sbjct: 88 TLCG--QESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC--- 142
Query: 1601 GNIMNGTRLGMDYKLGSTVT-YYCD--AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1657
+ G D+ + + +YC AGYVL +R +C A
Sbjct: 143 -QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVL------------------HRNKRTCSAL 183
Query: 1658 C-GSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV-FFQTSLH-DVVEVY 1714
C G T G + SP YP+ Y +C YSI++ + F V FV F H + + Y
Sbjct: 184 CSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPY 243
Query: 1715 DGPTQQSSLLSSLSGSHSGESLP---LSSGNQITIRFTS--VGPITAKGFHFVYQAVPRT 1769
D Q+ G G++LP + N +TI F + G T H+ A P
Sbjct: 244 DFLKIQTD--REEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQP-- 299
Query: 1770 SSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGY-ILHGSIAIRCET-VPNSLAQWN 1825
C P G + ++ + S C GY +L G + ++ T V W+
Sbjct: 300 ----CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWD 355
Query: 1826 DSLPTC-IVPCG 1836
+P C IV CG
Sbjct: 356 RPMPACSIVDCG 367
Score = 78.6 bits (192), Expect = 1e-13
Identities = 99/450 (22%), Positives = 157/450 (34%), Gaps = 92/450 (20%)
Query: 250 GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYLEIEGSEPPTI 305
G ++SP FP EY N+ + WT+ A PG + L FT F +E +YD++++
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 306 WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSR----------GF 355
L G + R G Y + ++D R GF
Sbjct: 88 TLCGQE-----------------STDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGF 130
Query: 356 KLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQ 415
+ F ++ ++ + G T + C + +G + SC YVL
Sbjct: 131 EAFYAAEDIDECQVA-PGEAPTCDHHCHN--------HLGGFYC-------SCRAGYVLH 174
Query: 416 GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT 475
K C G SG +SP +P Y + C + I+
Sbjct: 175 RNKR------------------TCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSIS 216
Query: 476 AVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWL 535
VI E FD+E +TL D ++ R G +P I + S+ + +
Sbjct: 217 LEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTI 276
Query: 536 HLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYG--IREGDGFSNRDVLRFECQFGFEL- 592
TDES G+K++Y + C P P G + +D C+ G+EL
Sbjct: 277 TFVTDESGDHTGWKIHYTS-TAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELL 335
Query: 593 -----IGEKSIVCQENNQWSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWT 646
+ + VCQ++ W +P C I C P G V
Sbjct: 336 QGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRV-----------------E 378
Query: 647 IISDPGSRIHLSFNDFDLESQFDFLAVKDG 676
I+ PG + + + E F + V DG
Sbjct: 379 YITGPGVTTYKAVIQYSCEETFYTMKVNDG 408
Score = 77.8 bits (190), Expect = 2e-13
Identities = 97/368 (26%), Positives = 144/368 (39%), Gaps = 56/368 (15%)
Query: 972 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHH----DYLLITENGSFTQ 1027
G + SPG+P Y N WT+ G ++ F F LE H D++ ++ S +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS---SGAK 84
Query: 1028 PLARLTGSDLPPTINAGLYGNFRA-----QLRFISDFSIS--YEGFNITFSEYNLEPCE- 1079
LA L G + T A F + + F SD+S + GF ++ +++ C+
Sbjct: 85 VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQV 144
Query: 1080 DPG-IPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC- 1137
PG P + G SC +GY L C A C
Sbjct: 145 APGEAPTCDHHCHNHLG---GFYCSCRAGYVLHRNKRT----------------CSALCS 185
Query: 1138 GASATNNEGILLSPNYPLNYENNHECIYSIQVQAG--------KGINISARTFHLAQGDV 1189
G T G L SP YP Y C YSI ++ G + ++ L D
Sbjct: 186 GQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDF 245
Query: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
LKI D+ H G F G ++ + + SN + + F +D G G+++ YTS
Sbjct: 246 LKIQ--TDREEH--GPFCGKTLPH-RIETKSNTVTITFVTDESGDHTGWKIHYTS-TAQP 299
Query: 1250 CEDPGIPQFGYKISDQG-HFAGSTIIYGCNPGY-TLHGSSLLKCMTG---ERRAWDYPLP 1304
C P P G+ Q + + C GY L G LK T + +WD P+P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 1305 SC-IAECG 1311
+C I +CG
Sbjct: 360 ACSIVDCG 367
Score = 73.6 bits (179), Expect = 3e-12
Identities = 98/404 (24%), Positives = 146/404 (36%), Gaps = 80/404 (19%)
Query: 74 GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLSLYDGHPH-P 128
G + SPGFP Y N W + A R+++ F F LE EYD++ L G
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 129 TNFRTRLTGFHLPP---PVTSTKSVFSLRLTSDFAVSAH--GFKVYYEELQSSSCG-NPG 182
T T P S S + SD++ GF+ +Y C PG
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
Query: 183 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 242
P + G SC GY+L + + TC A +C G
Sbjct: 148 EAPTCDHHCHNHLGG--FYCSCRAGYVLHRNKR-TCSA-------------LCS-----G 186
Query: 243 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTD-FQMEE------KYDYL 295
SG +SSP +P Y + CT++I E G ++ L F + F +E YD+L
Sbjct: 187 QVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFL 246
Query: 296 EIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGF 355
+I+ G +P I + N + + FVTD + + G+ Y
Sbjct: 247 KIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHY------------- 293
Query: 356 KLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENG--KRIGSDFSLGSTVQFSCDEDY- 412
+ + CP P P NG + + + L + C+ Y
Sbjct: 294 --------------------TSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYE 333
Query: 413 VLQG---AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSG 453
+LQG KS T + + +W P C + CG PSG
Sbjct: 334 LLQGHLPLKSFTA--VCQKDGSWDRPMPACSIVDCGPPDDLPSG 375
Score = 63.2 bits (152), Expect = 5e-09
Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 19/204 (9%)
Query: 56 SCVKGFIY-----TCGGTLKGL-----NGTIESPGFPYGYPNGANCTWVIIAEERNRIQI 105
SC G++ TC G +G + SP +P YP ++CT+ I EE + +
Sbjct: 166 SCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVIL 225
Query: 106 VF-QSFALEEEYDYLSLYDGHPHPTNFRTR--LTGFHLPPPVTSTKSVFSLRLTSDFAVS 162
F +SF +E + L YD T+ G LP + + + ++ +D +
Sbjct: 226 DFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGD 285
Query: 163 AHGFKVYYEELQSSSCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGY-ILDGH-PQLTC 218
G+K++Y + C P PP G + ++ + D C TGY +L GH P +
Sbjct: 286 HTGWKIHYTS-TAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSF 344
Query: 219 IANSVNTASWDFPVPICRAEDACG 242
A SWD P+P C D CG
Sbjct: 345 TAVCQKDGSWDRPMPACSIVD-CG 367
Score = 60.5 bits (145), Expect = 3e-08
Identities = 59/203 (29%), Positives = 80/203 (39%), Gaps = 38/203 (18%)
Query: 2880 SGDATG----------TCGDPGTP--GHGSRQESNFRTKSTVRYACDTGY-ILHG----- 2921
SGD TG C P P GH S ++ + K + C+TGY +L G
Sbjct: 283 SGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLK 342
Query: 2922 SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG---TTFSSSVIYSCMEGY-- 2976
S C +GSW P C V CG P +G+V I G TT+ + + YSC E +
Sbjct: 343 SFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYT 402
Query: 2977 --ILSGPSVRQCTANGTWSG-----TLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYM 3029
+ G V C A+G W+ +LP C + CG G YG GQ
Sbjct: 403 MKVNDGKYV--CEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGRIYG-----GQKAKPG 454
Query: 3030 CQPGYTMELNGSRIRTCTINGTW 3052
P + L G+ + W
Sbjct: 455 DFPWQVLILGGTTAAGALLYDNW 477
Score = 53.9 bits (128), Expect = 3e-06
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 16/137 (11%)
Query: 2706 CGHPGSPIYGRTSGNGFNF--NDVVTFSCNIGY-LMQG--PTK---AQCQANRQWSHPPP 2757
C +P +P G S + D + C GY L+QG P K A CQ + W P P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2758 MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF--GSSVLICQPNGQW- 2814
C +V+C P + + E G TY V+ Y C ++ +C+ +G W
Sbjct: 360 ACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWT 419
Query: 2815 ----DKPLPECIMIDCG 2827
+K LP C + CG
Sbjct: 420 SSKGEKSLPVCEPV-CG 435
Score = 53.5 bits (127), Expect = 4e-06
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 2792 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA----VLSGEKYTFGST 2847
Y+ G+ S +CQ +G WD+P+P C ++DCG P P+ + T+ +
Sbjct: 332 YELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAV 391
Query: 2848 VHYSC--TGKRSLLGQSSRTCQLNGHWSGSQ 2876
+ YSC T + C+ +G W+ S+
Sbjct: 392 IQYSCEETFYTMKVNDGKYVCEADGFWTSSK 422
Score = 51.6 bits (122), Expect = 1e-05
Identities = 96/431 (22%), Positives = 148/431 (34%), Gaps = 85/431 (19%)
Query: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQS 2418
G + SPG+P Y N Q W+++ GY + ++ F E E+D +++ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 2419 PVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNKK--GFRIRYIAFYCS------- 2466
+ S D A S G + + + +D+ N K GF AFY +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFE----AFYAAEDIDECQ 143
Query: 2467 -TPESPP--HGYIISQTGGQLNSVVRWACDRGFRLVGKS---SAVCRKSSYGYHAWDA-- 2518
P P + + GG S C G+ L SA+C + + +
Sbjct: 144 VAPGEAPTCDHHCHNHLGGFYCS-----CRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 2519 ---PVPACQAISCGIPKAPTNGGILTTDYLVGTRVTY----------------------F 2553
P P + SC + G + D++ V F
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPF 258
Query: 2554 CNDG--YRLSSKELT---TAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSY 2608
C +R+ +K T T V G + C PPNG+ Q Y
Sbjct: 259 CGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKY 318
Query: 2609 ---GSTAIFTCDLGFMLVG------SAVRECLSSGLWSESETRCLAGHCGIPELIVNGQV 2659
S +IF C+ G+ L+ S C G W C CG P+ + +G+V
Sbjct: 319 ILKDSFSIF-CETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRV 377
Query: 2660 ---IGENY-GYRDTVVYQCNPGF--RLIGSSVRICQQDHNWSG-----QLPSCVPVSCGH 2708
G Y+ + Y C F + +C+ D W+ LP C PV CG
Sbjct: 378 EYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPV-CGL 436
Query: 2709 PGSPIYGRTSG 2719
GR G
Sbjct: 437 SARTTGGRIYG 447
Score = 50.8 bits (120), Expect = 2e-05
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 23/158 (14%)
Query: 3058 TCRAVTCPTPPQISNGRLEGTNFDWGF--SISYICSPGYEL--------SFPAVLTCVGN 3107
T A CP P NG + + S S C GYEL SF AV C +
Sbjct: 294 TSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAV--CQKD 351
Query: 3108 GTWSGEVPQCLPKFCGDPGIPAQGKREGKS----FIYQSEVSFSCNFPF--ILVGSSTRI 3161
G+W +P C CG P G+ E + Y++ + +SC F + V +
Sbjct: 352 GSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYV 411
Query: 3162 CQADGTWSGSS-----PHCIEPTQTSCENPGVPRHGSQ 3194
C+ADG W+ S P C S G +G Q
Sbjct: 412 CEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQ 449
Score = 48.5 bits (114), Expect = 1e-04
Identities = 38/157 (24%), Positives = 65/157 (41%), Gaps = 27/157 (17%)
Query: 2942 AVQCGNPGTTANGKVFRI-------DGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSG 2994
A C P NG V + D + Y ++G++ C +G+W
Sbjct: 297 AQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDR 356
Query: 2995 TLPNCTIISCGDP-GIPANGLRYGDDYVVGQNVS-------YMCQPG-YTMELNGSRIRT 3045
+P C+I+ CG P +P+ + +Y+ G V+ Y C+ YTM++N +
Sbjct: 357 PMPACSIVDCGPPDDLPSGRV----EYITGPGVTTYKAVIQYSCEETFYTMKVNDGKY-V 411
Query: 3046 CTINGTWSG-----VMPTCRAVTCPTPPQISNGRLEG 3077
C +G W+ +P C V C + + GR+ G
Sbjct: 412 CEADGFWTSSKGEKSLPVCEPV-CGLSARTTGGRIYG 447
Score = 43.5 bits (101), Expect = 0.004
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 19/134 (14%)
Query: 2648 CGIPELIVNGQV--IGENYGYRDTVVYQCNPGFRLIG------SSVRICQQDHNWSGQLP 2699
C P NG V + Y +D+ C G+ L+ S +CQ+D +W +P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2700 SCVPVSCGHPGSPIYGRT---SGNGF-NFNDVVTFSCNIGY--LMQGPTKAQCQANRQWS 2753
+C V CG P GR +G G + V+ +SC + + K C+A+ W+
Sbjct: 360 ACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWT 419
Query: 2754 HPP-----PMCKVV 2762
P+C+ V
Sbjct: 420 SSKGEKSLPVCEPV 433
Score = 43.1 bits (100), Expect = 0.005
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 23/151 (15%)
Query: 2826 CGHPGVPPNAVLSG--EKYTFGSTVHYSC-TGKRSLLGQS-----SRTCQLNGHWSGSQP 2877
C +P PPN +S KY + C TG L G + CQ +G W P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 2878 HCSGDATGTCGDPGTPGHGSRQ----ESNFRTKSTVRYAC-DTGYILHGSEER-TCLANG 2931
CS CG P G + K+ ++Y+C +T Y + ++ + C A+G
Sbjct: 360 ACS---IVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADG 416
Query: 2932 SWTGRQ-----PECKAVQCGNPGTTANGKVF 2957
WT + P C+ V CG T G+++
Sbjct: 417 FWTSSKGEKSLPVCEPV-CGLSARTTGGRIY 446
Score = 40.0 bits (92), Expect = 0.041
Identities = 26/108 (24%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 3200 FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANV---VGM 3256
F + + +GHL S T C D +W P C C P+ V G
Sbjct: 324 FSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGP 383
Query: 3257 DLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNTWTG-----KVPICE 3298
+ ++ + Y+C+ F+ + + VC +D WT +P+CE
Sbjct: 384 GVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCE 431
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 125 bits (313), Expect = 1e-27
Identities = 93/302 (30%), Positives = 133/302 (44%), Gaps = 40/302 (13%)
Query: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSL-DFYD 1893
CGG+L+ +G SP YP+PY N +CVW I V IQ+++ + + E L D +
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 1894 GGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI--GLDSCPEP 1951
L G P LN+ +++L + F SD SV GFH Y A+ G SC
Sbjct: 204 LSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSCAHD 263
Query: 1952 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS----HITCMPGPVRRWNYPIPICLAQ- 2006
+ F+CDQ L S C G C A+
Sbjct: 264 E-------------------FRCDQLICLLPDSVCDGFANCADGSDET------NCSAKF 298
Query: 2007 --CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
CGG ++ G +P + YP L CTW I++P G + LQF NFS E DY
Sbjct: 299 SGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDY 358
Query: 2061 LEV-RSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2119
+EV + SS +++GR G + P L S+ HE ++ F +D+ + GF Y A+
Sbjct: 359 VEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATE 418
Query: 2120 CP 2121
P
Sbjct: 419 NP 420
Score = 117 bits (293), Expect = 2e-25
Identities = 95/306 (31%), Positives = 131/306 (42%), Gaps = 45/306 (14%)
Query: 443 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 498
TCG L GP G F+SPN+P Y N CVW I V T+ IQ+ E +E +D
Sbjct: 143 TCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHI-QVATDHAIQLKIEALSIESVASCLFDR 201
Query: 499 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE-- 556
L + +P L + G P + + +S + + +D SV GF Y+ +
Sbjct: 202 LELSP-----EPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 256
Query: 557 KESCG------DPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANI 610
+ SC D L DGF+N C G + N
Sbjct: 257 RGSCAHDEFRCDQLICLLPDSVCDGFAN-------CADGSD---------------ETNC 294
Query: 611 PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ--- 667
C N T GT +P Y + Y + L C W I G I L F++F LE+Q
Sbjct: 295 SAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDEC 354
Query: 668 -FDFLAVKDGDSPES-PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTF 725
FD++ V + S + +LG F GAE P HL S+ H L + F+ DH +S GF+ TY F
Sbjct: 355 KFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAF 414
Query: 726 GHNECP 731
E P
Sbjct: 415 NATENP 420
Score = 108 bits (271), Expect = 7e-23
Identities = 98/349 (28%), Positives = 147/349 (42%), Gaps = 45/349 (12%)
Query: 749 GSSISVICEEGFIKTQGTETITCILMDGKVMW---SGLIPKCGAPCGGHFSAPSGVILSP 805
G+S S + G T T TIT G SG+ P + CGG S P G SP
Sbjct: 99 GASHSPLPAGGLTTTTTTPTITTSQAAGTPKGQQESGVSPSPQSTCGGLLSGPRGFFSSP 158
Query: 806 GWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSY 861
+P Y + +C W I+ H+I++ E E +D LE+ P PLL
Sbjct: 159 NYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLELSPEPE--GPLL-RV 215
Query: 862 NGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD 921
G P L ++++ + ++F +D+S GF Y+++ SC HD
Sbjct: 216 CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSC------------AHD 263
Query: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDAL---CGGDVRGPSGTILSPG 978
F CD L + N C A CGG++ G GT +P
Sbjct: 264 -------EFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPS 316
Query: 979 YPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITE---NGSFTQPLAR 1031
Y + YP+ L CTW + V G ++ FH F LE DY+ + E +G+F+ L R
Sbjct: 317 YLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSL-LGR 375
Query: 1032 LTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNL--EPC 1078
G++ PP + + + + F +D IS GF+ T+ +N PC
Sbjct: 376 FCGAEPPPHL---VSSHHELAVLFRTDHGISSGGFSATYLAFNATENPC 421
Score = 99.0 bits (245), Expect = 7e-20
Identities = 82/293 (27%), Positives = 121/293 (41%), Gaps = 38/293 (12%)
Query: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 119
TCGG L G G SP +P YP +C W I + IQ+ ++ ++E +D L
Sbjct: 143 TCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRL 202
Query: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
L P P R+ G PP + + S + SD +V GF +Y+ +
Sbjct: 203 EL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAM------ 253
Query: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE- 238
P +G F I + + DG ++ N C A+
Sbjct: 254 ---APGRGSCAHDEFRCDQLI--CLLPDSVCDGFANCADGSDETN----------CSAKF 298
Query: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 294
CGG + G G S+PS+ +Y + CTW I G +I L F +F +E K+DY
Sbjct: 299 SGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDY 358
Query: 295 LEI-EGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
+E+ E S L G PP ++S+ + L + F TD GFSA Y
Sbjct: 359 VEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 99.0 bits (245), Expect = 7e-20
Identities = 84/305 (27%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 617 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLA 672
C + P G SP+YP+ Y N +C+W I I L +ES FD L
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 673 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTF--GHNEC 730
+ PE P+L P+ T+ SH+L + F +D S+ G GF+ Y G C
Sbjct: 204 L--SPEPEGPLLRVCGRVPPPTLNTNASHLL-VVFVSDSSVEGFGFHAWYQAMAPGRGSC 260
Query: 731 PDPGIPINARRFGDNFQLGSSISVICE---EGFIK-TQGTETITCILMDGKVMWSGLIPK 786
D F+ I ++ + +GF G++ C +SG
Sbjct: 261 AH-----------DEFRCDQLICLLPDSVCDGFANCADGSDETNC-----SAKFSG---- 300
Query: 787 CGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF----QTELNY 842
CGG+ + G +P + Y L C W I GHSI++ F F Q E +
Sbjct: 301 ----CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKF 356
Query: 843 DVLEVHD-GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTV 901
D +EV++ + LLG + G + P L SS + + +LF TD+ S+ GF Y +
Sbjct: 357 DYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNA 416
Query: 902 NTYSC 906
C
Sbjct: 417 TENPC 421
Score = 93.6 bits (231), Expect = 3e-18
Identities = 90/310 (29%), Positives = 134/310 (43%), Gaps = 41/310 (13%)
Query: 1475 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN 1534
PSP + CGG L+G GF SPN+P PYP + C W I V D+ I L + SIE
Sbjct: 138 PSPQ---STCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESV 194
Query: 1535 YDFLY--IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAK 1592
L+ + P+ PL+ P + ++++ + + F SD SV GFH Y+A
Sbjct: 195 ASCLFDRLELSPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQA- 252
Query: 1593 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
PG G+ +++ + D+ V G++ C G D
Sbjct: 253 -----MAPG---RGSCAHDEFRCDQLICLLPDS--VCDGFA--NCADGSDE--------T 292
Query: 1653 SCHAP---CGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLH- 1708
+C A CG TG +GT +P+Y + Y C + I+VP + QF F
Sbjct: 293 NCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQD 352
Query: 1709 ----DVVEVYDGPTQQSSLLSSLSGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHF 1761
D VEVY+ SS SL G G P +SS +++ + F + I++ GF
Sbjct: 353 ECKFDYVEVYE---TSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSA 409
Query: 1762 VYQAVPRTSS 1771
Y A T +
Sbjct: 410 TYLAFNATEN 419
Score = 89.4 bits (220), Expect = 6e-17
Identities = 90/334 (26%), Positives = 138/334 (41%), Gaps = 43/334 (12%)
Query: 2173 PRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD- 2231
P ++ CGG ++ G SP YPD YP C W ++V + I + L E +
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASC 197
Query: 2232 -FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRV 2290
F + P+ P + + G ++ + ++ +L+ F SD + GF +HA+
Sbjct: 198 LFDRLELSPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGF---GFHAWY--- 250
Query: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV-CQ 2349
Q P + DEF +I LP G A C DG+ C
Sbjct: 251 -QAMAPGRGS---CAHDEFRCDQLICL--LPDSVCDGFA--NCA-------DGSDETNCS 295
Query: 2350 VL---CPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF----QTE 2402
C N L G +P Y YP+ +C W ISV G++I + F Q E
Sbjct: 296 AKFSGCGGNLTGLQ--GTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDE 353
Query: 2403 KEFDVLQVYDGPNIQSPVLISLSGDYSSAF---NITSNGHEVFLQWSADHGNNKKGFRIR 2459
+FD ++VY+ S SL G + A ++ S+ HE+ + + DHG + GF
Sbjct: 354 CKFDYVEVYE---TSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSAT 410
Query: 2460 YIAFYCSTPESPPHGYIISQTGGQLNSVVRWACD 2493
Y+AF + P + Q GG V+W CD
Sbjct: 411 YLAFNATENPCGP-SELSCQAGGCKG--VQWMCD 441
Score = 82.0 bits (201), Expect = 9e-15
Identities = 78/324 (24%), Positives = 121/324 (37%), Gaps = 62/324 (19%)
Query: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 293
+ CGG + G G SSP++P+ Y N C W I I L +E +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 294 YLEIEGS-EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKS 352
LE+ E P + + G PP + +N + L + FV+DS+ GF A YQ
Sbjct: 201 RLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQA-------- 252
Query: 353 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDY 412
+ PG+ + + +F CD+
Sbjct: 253 ----MAPGRGSC-------------------------------------AHDEFRCDQLI 271
Query: 413 VLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVW 472
L C A + K CG NL G GTF++P++ QY C W
Sbjct: 272 CL--LPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTW 329
Query: 473 VITAVNTNKVIQINFEEFDL----EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVS 528
I +V I++ F F L E +D + + + G ++L G+ P +VS
Sbjct: 330 HI-SVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSG-AFSLLGRFCGAEPPPHLVS 387
Query: 529 MSSQMWLHLQTDESVGSVGFKVNY 552
++ + +TD + S GF Y
Sbjct: 388 SHHELAVLFRTDHGISSGGFSATY 411
Score = 77.8 bits (190), Expect = 2e-13
Identities = 74/300 (24%), Positives = 115/300 (38%), Gaps = 34/300 (11%)
Query: 957 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1016
P+ + CGG + GP G SP YP+ YP + +C W + V +Q +E
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASC 197
Query: 1017 LL--ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
L + + PL R+ G PPT+N + F+SD S+ GF+ +
Sbjct: 198 LFDRLELSPEPEGPLLRVCGRVPPPTLNTNA---SHLLVVFVSDSSVEGFGFHAWYQAM- 253
Query: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
P GS F + S +C G + C
Sbjct: 254 --------APGRGSCAHDEFRCDQLICLLPDS----------VCDGFANCADGSDETNCS 295
Query: 1135 AE---CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQ 1186
A+ CG + T +G +P+Y Y + C + I V AG I + F L +
Sbjct: 296 AKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECK 355
Query: 1187 GDVLKIYD-GKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSF 1245
D +++Y+ LLG F GA L S+ ++L + F +D + GF Y +F
Sbjct: 356 FDYVEVYETSSSGAFSLLGRFCGAEPPP-HLVSSHHELAVLFRTDHGISSGGFSATYLAF 414
Score = 61.6 bits (148), Expect = 1e-08
Identities = 74/306 (24%), Positives = 114/306 (37%), Gaps = 40/306 (13%)
Query: 1131 PRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVL 1190
P + CG + G SPNYP Y N C++ IQV I + + +
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSI-ESVAS 196
Query: 1191 KIYDGKDKTTHLLGAFTGASMR--GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELS 1248
++D + + G R TL++ ++ L + F SD+ GF Y +
Sbjct: 197 CLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMA-- 254
Query: 1249 HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLL----KCMTGERRAWDYPLP 1304
P G D+ + C+ L S+ C G
Sbjct: 255 -------PGRGSCAHDE---------FRCDQLICLLPDSVCDGFANCADGSDET------ 292
Query: 1305 SCIAE---CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA- 1360
+C A+ CGG G G +P Y Y + L C W I V G+ + LQF F EA
Sbjct: 293 NCSAKFSGCGGNLTG-LQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQ 351
Query: 1361 ---SHDILRVWDGPPENDM-LLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1416
D + V++ LL G+ P + S+ + + + F TD IS GF+ +
Sbjct: 352 DECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Query: 1417 SSSVAT 1422
+ AT
Sbjct: 412 LAFNAT 417
Score = 61.2 bits (147), Expect = 2e-08
Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 7/125 (5%)
Query: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
CGG L GL GT +P + YP+ CTW I + I++ F +F+LE + +DY+
Sbjct: 301 CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVE 360
Query: 121 LYD-GHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
+Y+ + R G PP + S+ ++ +D +S+ GF Y L ++
Sbjct: 361 VYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY--LAFNATE 418
Query: 180 NPGVP 184
NP P
Sbjct: 419 NPCGP 423
Score = 36.2 bits (82), Expect = 0.59
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 2340 QMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF 2399
Q G P Q C L G SP YPD YP C W I V + I + +E
Sbjct: 132 QESGVSPSPQSTCGG--LLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEAL 189
Query: 2400 QTEKE----FDVLQVYDGPNIQSPVL 2421
E FD L++ P + P+L
Sbjct: 190 SIESVASCLFDRLEL--SPEPEGPLL 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 164,426,159
Number of Sequences: 37866
Number of extensions: 8626334
Number of successful extensions: 32413
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 15952
Number of HSP's gapped (non-prelim): 6347
length of query: 3538
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3416
effective length of database: 13,627,866
effective search space: 46552790256
effective search space used: 46552790256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.