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Search of human proteins with 20373181
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3
precursor [Homo sapiens]
(533 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 pre... 1105 0.0
gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 pre... 1086 0.0
gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Ho... 617 e-177
gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1 pre... 314 1e-85
gi|126091152 cubilin [Homo sapiens] 126 4e-29
gi|22547221 tolloid-like 1 [Homo sapiens] 116 6e-26
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 113 5e-25
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 113 5e-25
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 113 5e-25
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 113 5e-25
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 113 5e-25
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 113 5e-25
gi|6912724 tolloid-like 2 [Homo sapiens] 112 6e-25
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 108 2e-23
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 103 5e-22
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 103 5e-22
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 102 7e-22
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 102 7e-22
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 102 7e-22
gi|13899255 membrane frizzled-related protein [Homo sapiens] 102 7e-22
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 93 7e-19
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 80 5e-15
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 76 7e-14
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 75 1e-13
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 75 2e-13
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 71 3e-12
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 71 3e-12
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 71 3e-12
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 70 4e-12
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 70 4e-12
>gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3
precursor [Homo sapiens]
Length = 533
Score = 1105 bits (2858), Expect = 0.0
Identities = 533/533 (100%), Positives = 533/533 (100%)
Query: 1 MIHGRSVLHIVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPS 60
MIHGRSVLHIVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPS
Sbjct: 1 MIHGRSVLHIVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPS 60
Query: 61 KYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQ 120
KYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQ
Sbjct: 61 KYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQ 120
Query: 121 QNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSE 180
QNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSE
Sbjct: 121 QNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSE 180
Query: 181 GIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGS 240
GIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGS
Sbjct: 181 GIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGS 240
Query: 241 SSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCH 300
SSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCH
Sbjct: 241 SSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCH 300
Query: 301 SNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIIS 360
SNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIIS
Sbjct: 301 SNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIIS 360
Query: 361 VIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKL 420
VIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKL
Sbjct: 361 VIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKL 420
Query: 421 RRSSSKCIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKH 480
RRSSSKCIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKH
Sbjct: 421 RRSSSKCIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKH 480
Query: 481 NYSQDAADACDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV 533
NYSQDAADACDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV
Sbjct: 481 NYSQDAADACDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV 533
>gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2
precursor [Homo sapiens]
Length = 532
Score = 1086 bits (2809), Expect = 0.0
Identities = 523/524 (99%), Positives = 524/524 (100%)
Query: 10 IVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 69
+VASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI
Sbjct: 9 VVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 68
Query: 70 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 129
YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS
Sbjct: 69 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 128
Query: 130 GRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIM 189
GRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIM
Sbjct: 129 GRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIM 188
Query: 190 KEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAK 249
KEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAK
Sbjct: 189 KEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAK 248
Query: 250 FCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTL 309
FCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTL
Sbjct: 249 FCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTL 308
Query: 310 VCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQPR 369
VCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQPR
Sbjct: 309 VCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQPR 368
Query: 370 KKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSSSKCIH 429
KKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSSSKCIH
Sbjct: 369 KKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSSSKCIH 428
Query: 430 DHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKHNYSQDAADA 489
DHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKHNYSQDAADA
Sbjct: 429 DHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKHNYSQDAADA 488
Query: 490 CDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV 533
CDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV
Sbjct: 489 CDIDEIEEVPTTSHRLSRHDKAVQRFCLIGSLSKHESEYNTTRV 532
>gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Homo
sapiens]
Length = 525
Score = 617 bits (1592), Expect = e-177
Identities = 294/510 (57%), Positives = 380/510 (74%), Gaps = 14/510 (2%)
Query: 10 IVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 69
++ L++ ++ A K + + + QCG W + + GG F SPNYP YPP++ECI
Sbjct: 14 LITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASPNYPDSYPPNKECI 73
Query: 70 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 129
YI+EAAPRQ IEL FDE Y IEPS+EC+FDH+EVRDGPFGFSP+I R+CG ++PP+I+S+
Sbjct: 74 YILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRST 133
Query: 130 GRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGA-LKPLPACEFEMGGSEGIVESIQI 188
GRF+WIKF +D ELE +GF A+Y+F PDPDF LG L P+P C+FE+ G++GIV S Q+
Sbjct: 134 GRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQV 193
Query: 189 MKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKA 248
+E K +AVDC W I+A P++KIYLRFLDY+M++SNECKRNFVAVYDGSSS+E+LKA
Sbjct: 194 EQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKA 253
Query: 249 KFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNT 308
KFCSTVANDVML+TG+GVIRMWADEGSR SRF+MLFTSF EPPC +TFFCHSNMCINN+
Sbjct: 254 KFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSNMCINNS 313
Query: 309 LVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQP 368
LVCNG+QNC YPWDENHCKEK+K + +Q+T T GT+IG+TS IV++L+IIS++VQ+KQP
Sbjct: 314 LVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGTIIGITSGIVLVLLIISILVQVKQP 373
Query: 369 RKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSS--SK 426
RKK + K+ F++T FQEVF+PPHYEL +LR +AD AD++++ +NY K+RRSS S+
Sbjct: 374 RKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELDNYQKMRRSSTASR 433
Query: 427 CIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIPPMNRRNILVMKHNYSQDA 486
CIHDHHCGSQ SS K SR+NLS+ E+P + PM N K +Y+
Sbjct: 434 CIHDHHCGSQASSVKQSRTNLSS------MELPFRNDFAQPQPMKTFNSTFKKSSYTFKQ 487
Query: 487 ADACDIDEI-----EEVPTTSHRLSRHDKA 511
C + EE+P + R D A
Sbjct: 488 GHECPEQALEDRVMEEIPCEIYVRGREDSA 517
>gi|20452470 neuropilin- and tolloid-like protein 1 isoform 1
precursor [Homo sapiens]
Length = 156
Score = 314 bits (804), Expect = 1e-85
Identities = 146/148 (98%), Positives = 148/148 (100%)
Query: 10 IVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 69
+VASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI
Sbjct: 9 VVASLIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECI 68
Query: 70 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 129
YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS
Sbjct: 69 YIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSS 128
Query: 130 GRFLWIKFFADGELESMGFSARYNFTPD 157
GRFLWIKFFADGELESMGFSARYNFTP+
Sbjct: 129 GRFLWIKFFADGELESMGFSARYNFTPE 156
Score = 33.1 bits (74), Expect = 0.65
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 201 DCKWYIRAPPRSKIYLRFLD-YEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVM 259
+C + I A PR I L F + Y ++ S ECK + + V DG + +FC V+
Sbjct: 66 ECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVI 125
Query: 260 LRTGLGV-IRMWAD 272
+G + I+ +AD
Sbjct: 126 KSSGRFLWIKFFAD 139
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 126 bits (317), Expect = 4e-29
Identities = 77/265 (29%), Positives = 138/265 (52%), Gaps = 28/265 (10%)
Query: 37 KSVQCG--TWTKHAEG-GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS 93
KS+ CG + A+ G TSPN+P YPP +CI+I+ A P I+L F++++ IE +
Sbjct: 2213 KSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVT 2272
Query: 94 WECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 153
C +++E+RDG +PI+ +FCG P SSG ++++F +D +GF A+Y+
Sbjct: 2273 PNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYS 2332
Query: 154 FTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATA--SEAVDCKWYIRAPPR 211
+ C + G G+VESI G T + + C+W+++
Sbjct: 2333 ---------------IAQCGGRVPGQSGVVESI-----GHPTLPYRDNLFCEWHLQGLSG 2372
Query: 212 SKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC-STVANDVMLRTGLGVIRMW 270
+ + F D+ +QNS+ C+++FV ++D +S ++ ++C +T+ + + + V+R
Sbjct: 2373 HYLTISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCGNTIPDSIDTSSNTAVVRFV 2431
Query: 271 ADEGSRNSRFQMLFTSFQEPPCEGN 295
D S F++ F S E C G+
Sbjct: 2432 TDGSVTASGFRLRFESSME-ECGGD 2455
Score = 100 bits (249), Expect = 3e-21
Identities = 68/232 (29%), Positives = 104/232 (44%), Gaps = 18/232 (7%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G FTSPN+P+ YP + ECIY I Q I ++F E D +E+RDG +
Sbjct: 1057 GTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEK 1116
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
SP++G F G PP I S LW+KF +D GFSA + D G
Sbjct: 1117 SPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYW------DGSSTGC----- 1165
Query: 171 ACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECK 230
GG+ I + +C W++++ S L F D+ +++ C
Sbjct: 1166 ------GGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCT 1219
Query: 231 RNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGV-IRMWADEGSRNSRFQ 281
+++AVYDG SS L + C ++ +G + I++ DEG + F+
Sbjct: 1220 LDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFK 1271
Score = 97.4 bits (241), Expect = 3e-20
Identities = 68/249 (27%), Positives = 109/249 (43%), Gaps = 19/249 (7%)
Query: 51 GIFTSPNYP-SKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFG 109
GI TSP Y + YP D C+Y I + + IEL F + + + PS C D++ + DG
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSD-FDVVPSTSCSHDYLAIYDGANT 3104
Query: 110 FSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPL 169
P++G+FCG + PP +KSS + + F D + G+ + T L P
Sbjct: 3105 SDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQT----------LGPQ 3154
Query: 170 PACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSN-- 227
C + GS S + + ++C W I AP I+L F + ++ ++
Sbjct: 3155 QGCGGYLTGSNNTFASPD--SDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTR 3212
Query: 228 -ECKRNFVAVYDGSSSVEDLKAKFC-STVANDVMLRTGLGVIRMWADEGSRNSRFQMLFT 285
C ++V +YDG S +L FC STV + ++ +D F +T
Sbjct: 3213 QRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYT 3272
Query: 286 SFQEPPCEG 294
+ PC G
Sbjct: 3273 -IMDMPCGG 3280
Score = 97.1 bits (240), Expect = 4e-20
Identities = 63/236 (26%), Positives = 106/236 (44%), Gaps = 30/236 (12%)
Query: 34 ETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPS 93
ETQ+ +CG G I SP YP YPP R+C++I+ +P + F S+E
Sbjct: 584 ETQQP-ECGGILTGPYGSI-KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT-LSLEHH 640
Query: 94 WECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 153
+C D++E+RDGP P++G+FC + P ++++G F I F +D ++ GF Y
Sbjct: 641 DDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 700
Query: 154 FTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSK 213
+P + GG+ E + E + C + ++ P +
Sbjct: 701 TSPS---------------DLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQ 745
Query: 214 IYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC--------STVANDVMLR 261
I + F E+Q ++ +N++ V DG E L K C ++ N V +R
Sbjct: 746 IQINFTHVELQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIR 797
Score = 93.2 bits (230), Expect = 5e-19
Identities = 64/239 (26%), Positives = 103/239 (43%), Gaps = 27/239 (11%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G F+SP +P++YPP++ECI+ I P I+L + + +E C FD +E+ GP
Sbjct: 1400 GSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHD-FDVEYHSRCNFDVLEIYGGPDFH 1458
Query: 111 SPIIGRFCGQ---QNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALK 167
SP I + C Q +NP + S+G L I+F D + GF+A + G +
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTG----GCGGIF 1514
Query: 168 PLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSN 227
P+ E S DC W IR ++ L F D++++ +
Sbjct: 1515 QAPSGEIHSPNYPSPYRS-------------NTDCSWVIRVDRNHRVLLNFTDFDLEPQD 1561
Query: 228 ECKRNFVAVYDGSSSVEDLKAKFC--STVANDVMLRTGLGVIRMWADEGSRNSRFQMLF 284
C + YDG SS A+ C +AN ++ +R + +N F+ F
Sbjct: 1562 SC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 90.5 bits (223), Expect = 3e-18
Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 23/191 (12%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G F SPNYP Y EC + ++++ EL F + + +E C D++ V DGP
Sbjct: 1174 GTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKD-FHLEHHPNCTLDYLAVYDGPSSN 1232
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
S ++ + CG + PP+I+SSG ++IK D + GF A Y T
Sbjct: 1233 SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYRQT--------------- 1277
Query: 171 ACE--FEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNE 228
CE + + GI+ESI SE C W IRA + + FL +++++
Sbjct: 1278 -CENVVIVNQTYGILESIGYPN----PYSENQHCNWTIRATTGNTVNYTFLAFDLEHHIN 1332
Query: 229 CKRNFVAVYDG 239
C +++ +YDG
Sbjct: 1333 CSTDYLELYDG 1343
Score = 85.5 bits (210), Expect = 1e-16
Identities = 58/242 (23%), Positives = 99/242 (40%), Gaps = 20/242 (8%)
Query: 47 HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDG 106
H G SP +P Y D++C + A I L+F IE S EC+ D +EVR+G
Sbjct: 3400 HKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFF-HSLGIENSVECRNDFLEVRNG 3458
Query: 107 PFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGAL 166
SP++G++CG P + S L+++F +D G+ + +P
Sbjct: 3459 SNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPS--------- 3509
Query: 167 KPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNS 226
C + G G S T C+W + AP + + F + +
Sbjct: 3510 ----GCGGTLYGDRGSFTS----PGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDP 3561
Query: 227 NECKRNFVAVYDGSSSVEDLKAKFC--STVANDVMLRTGLGVIRMWADEGSRNSRFQMLF 284
+C +N++ +YDG ++ +C T + + I+ AD R S F++ +
Sbjct: 3562 GDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTW 3621
Query: 285 TS 286
S
Sbjct: 3622 DS 3623
Score = 84.7 bits (208), Expect = 2e-16
Identities = 56/212 (26%), Positives = 100/212 (47%), Gaps = 20/212 (9%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPR-QCIELYFDEKYSIEPSWECKFD 99
CG + +SP +P+ YP ++ C +II+A P I L F + +E S C D
Sbjct: 1620 CGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTH-FELERSTTCARD 1678
Query: 100 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD 159
+E+ DG +P+ GR+CG P I S L ++F +D + + GF +
Sbjct: 1679 FVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTAS---- 1734
Query: 160 FKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFL 219
+ AC GG+ + E I V+C W I + P +++ L F+
Sbjct: 1735 ---------VSAC----GGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFI 1781
Query: 220 DYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC 251
+++++S +C R+FV + +G+++ L ++C
Sbjct: 1782 SFQLEDSQDCSRDFVEIREGNAT-GHLVGRYC 1812
Score = 81.6 bits (200), Expect = 2e-15
Identities = 60/230 (26%), Positives = 100/230 (43%), Gaps = 37/230 (16%)
Query: 32 TSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE 91
T+ T CG AEG IF SP YP YPP+ EC++ I ++P ++L F + +E
Sbjct: 1729 TTVTASVSACGGTFYMAEG-IFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSF-ISFQLE 1786
Query: 92 PSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKS-SGRFLWIKFFADGELESMGFSA 150
S +C D +E+R+G ++GR+CG P S G LW++F +DG GF A
Sbjct: 1787 DSQDCSRDFVEIREGN-ATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQA 1845
Query: 151 RYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATA-------SEAVDCK 203
+ ++ G++ IV + GK + + +
Sbjct: 1846 TF---------------------MKIFGNDNIVGT-----HGKVASPFWPENYPHNSNYQ 1879
Query: 204 WYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCST 253
W + ++ R L+ +++ C + + +YDG S L +C T
Sbjct: 1880 WTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCGT 1929
Score = 80.9 bits (198), Expect = 3e-15
Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 33/227 (14%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC---K 97
CG + HA+ GI TSP YP YP + C + + I ++F++ + I P+ + +
Sbjct: 2092 CGGYL-HADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQI-PNGDSSCNQ 2149
Query: 98 FDHIEVRDGPFGFSPII------GRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSAR 151
D++ +R+GP SP + G FCG + +S ++++F +D E GF +
Sbjct: 2150 GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIK 2209
Query: 152 YNFTPDPDFKDLGALKPLPACEFEM----GGSEGIVESIQIMKEGKATASEAVDCKWYIR 207
Y + K L AC + S G V S DC W +
Sbjct: 2210 Y------EAKSL-------ACGGNVYIHDADSAGYVTS----PNHPHNYPPHADCIWILA 2252
Query: 208 APPRSKIYLRFLD-YEMQNSNECKRNFVAVYDGSSSVEDLKAKFCST 253
APP ++I L+F D ++++ + C N++ + DG S + +KFC T
Sbjct: 2253 APPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGT 2299
Score = 80.5 bits (197), Expect = 4e-15
Identities = 61/210 (29%), Positives = 90/210 (42%), Gaps = 21/210 (10%)
Query: 49 EGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPF 108
+ G+ TSPNYP+ Y C ++EA I L F + + IEP C +D + VR+G
Sbjct: 2696 DSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSD-FDIEPHTTCAWDSVTVRNGGS 2754
Query: 109 GFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKP 168
SPIIG++CG NP I+S L + F +D L+ GF A +N + LG
Sbjct: 2755 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWN------TQTLG---- 2804
Query: 169 LPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEM--QNS 226
C G + S E C W + + F + +
Sbjct: 2805 ---CGGIFHSDNGTIRS----PHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGD 2857
Query: 227 NECKRNFVAVYDGSSSVED-LKAKFCSTVA 255
+C+ +FV V+ G+ V+ L A C VA
Sbjct: 2858 GQCQNSFVKVWAGTEEVDKALLATGCGNVA 2887
Score = 73.9 bits (180), Expect = 3e-13
Identities = 53/201 (26%), Positives = 87/201 (43%), Gaps = 20/201 (9%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ SP +P+ YP +R C + I Q I L F + I S C+ D++E+
Sbjct: 825 GVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTV-FEIGSSAHCETDYVEIGSSSILG 883
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
SP ++CG P I S FL++ F E+ GF A+++ +DL
Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFS------AEDL------- 930
Query: 171 ACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECK 230
AC + S G ++S ++C W+I P I+L F + ++ C
Sbjct: 931 ACGEILTESTGTIQS----PGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCT 986
Query: 231 RNFVAVYDGSSSVEDLKAKFC 251
+++ VYD S E ++C
Sbjct: 987 NDYLEVYDTDS--ETSLGRYC 1005
Score = 73.9 bits (180), Expect = 3e-13
Identities = 58/212 (27%), Positives = 92/212 (43%), Gaps = 34/212 (16%)
Query: 48 AEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGP 107
A G SPNYPS Y + +C ++I + L F + + +EP C I DG
Sbjct: 1516 APSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTD-FDLEPQDSC----IMAYDGL 1570
Query: 108 FGFSPIIGRFCGQQ---NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLG 164
+ R CG++ NP I SSG L+++F + ++ GF A++
Sbjct: 1571 SSTMSRLARTCGREQLANP--IVSSGNSLFLRFQSGPSRQNRGFRAQFR----------- 1617
Query: 165 ALKPLPACEFEMGGSEGIVESIQIMKEGKATAS--EAVDCKWYIRA-PPRSKIYLRFLDY 221
AC G + S + + A+ +C W I+A PP + I L F +
Sbjct: 1618 -----QAC-----GGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHF 1667
Query: 222 EMQNSNECKRNFVAVYDGSSSVEDLKAKFCST 253
E++ S C R+FV + DG L+ ++C T
Sbjct: 1668 ELERSTTCARDFVEILDGGHEDAPLRGRYCGT 1699
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/184 (30%), Positives = 85/184 (46%), Gaps = 19/184 (10%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDE-KYSIEPSWECKFDHIEVRDGPFG 109
G FTSPNYP+ P R C + I A + I L F+ + + PS C +H+ V +G
Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPS--CNNEHVIVFNGIRS 2518
Query: 110 FSPIIGRFCGQQN-PPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKP 168
SP + + C N IKSSG + + FF DG GF+A Y T D G+L
Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASY--TSSEDAVCGGSLPN 2576
Query: 169 LPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPR--SKIYLRFLDYEMQNS 226
P F G +G+ S ++C+W + P + S I + F D+ +++
Sbjct: 2577 TPEGNFTSPGYDGV-----------RNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESH 2625
Query: 227 NECK 230
+C+
Sbjct: 2626 QDCQ 2629
Score = 70.5 bits (171), Expect = 4e-12
Identities = 51/207 (24%), Positives = 87/207 (42%), Gaps = 24/207 (11%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEP----SWECKFDHIEVRDG 106
G SPNYP +Y + C Y+IEA P + L F + +E + C D + + G
Sbjct: 2929 GYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTF-VSFHLEARSAVTGSCVNDGVHIIRG 2987
Query: 107 PFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGAL 166
S CG + P + +G L + F+++ ++ GF Y
Sbjct: 2988 YSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYR------------- 3033
Query: 167 KPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNS 226
+ +C S GI+ S A + C + I I L+F D+++ S
Sbjct: 3034 --IISCGGVFNFSSGIITS---PAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPS 3088
Query: 227 NECKRNFVAVYDGSSSVEDLKAKFCST 253
C +++A+YDG+++ + L KFC +
Sbjct: 3089 TSCSHDYLAIYDGANTSDPLLGKFCGS 3115
Score = 68.6 bits (166), Expect = 1e-11
Identities = 58/219 (26%), Positives = 96/219 (43%), Gaps = 35/219 (15%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 98
++CG EG +F P + R+C+Y+++ + I++ F ++ +
Sbjct: 706 LRCGGNYTDPEGELFL-PELSGPFTHTRQCVYMMKQPQGEQIQINFTH-VELQCQSDSSQ 763
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDP 158
++IEVRDG ++G+ CG IKS +WI+F D +E F A Y
Sbjct: 764 NYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV---- 815
Query: 159 DFKDLGALKPLPACEFEMGGSEGIVES--IQIMKEGKATASEAVDCKWYIRAPPRSKIYL 216
AC E+ G EG++ S + G+ T C+W I P I L
Sbjct: 816 ------------ACGDELTG-EGVIRSPFFPNVYPGERT------CRWTIHQPQSQVILL 856
Query: 217 RFLDYEMQNSNECKRNFVAVYDGSSSV--EDLKAKFCST 253
F +E+ +S C+ ++V + GSSS+ K+C T
Sbjct: 857 NFTVFEIGSSAHCETDYVEI--GSSSILGSPENKKYCGT 893
Score = 67.8 bits (164), Expect = 2e-11
Identities = 74/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)
Query: 15 IILHLSGATKKG--TEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPS--KYPPDRECIY 70
+I G+ G T T+SE CG + G FTSP Y Y + C +
Sbjct: 2545 VIFFTDGSRPYGGFTASYTSSE---DAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEW 2601
Query: 71 IIEAAPRQ---CIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNP--PV 125
+ + P Q I ++F++ Y +E +C+FD +E R G P++ R CG P P+
Sbjct: 2602 TL-SNPNQGNSSISIHFEDFY-LESHQDCQFDVLEFRVGDAD-GPLMWRLCGPSKPTLPL 2658
Query: 126 IKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVES 185
+ + +WI F + +E +GF A+Y+FT D G ++ G G++ S
Sbjct: 2659 VIPYSQ-VWIHFVTNERVEHIGFHAKYSFT------DCGGIQI---------GDSGVITS 2702
Query: 186 IQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVED 245
C + AP I L F D++++ C + V V +G S
Sbjct: 2703 PNYPN----AYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESP 2758
Query: 246 LKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCI 305
+ ++C +N +++G Q++ T + +G F+ N
Sbjct: 2759 IIGQYCGN-SNPRTIQSGSN---------------QLVVTFNSDHSLQGGGFYATWN--- 2799
Query: 306 NNTLVCNGL 314
TL C G+
Sbjct: 2800 TQTLGCGGI 2808
Score = 62.8 bits (151), Expect = 8e-10
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 37 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 96
+ + CG + G I SP +P+ YP C + I P I L F E + +E + C
Sbjct: 928 EDLACGEILTESTGTI-QSPGHPNVYPHGINCTWHILVQPNHLIHLMF-ETFHLEFHYNC 985
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
D++EV D S +GR+CG+ PP + SSG L + F D +L GF Y
Sbjct: 986 TNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 61.6 bits (148), Expect = 2e-09
Identities = 58/239 (24%), Positives = 91/239 (38%), Gaps = 16/239 (6%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G SP +P YP + + + + E IE C +D + + DGP
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEM-DIEEIQNCYYDKLRIYDGPSIH 1919
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
+ +IG +CG Q S+G L F++D + GF + PD G L +
Sbjct: 1920 ARLIGAYCGTQTES-FSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPD----GVLPTIA 1974
Query: 171 --ACEFEMGG--SEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNS 226
AC GG G + S VDC W I+AP S + L L ++++
Sbjct: 1975 PGAC----GGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPD-STVELNILSLDIESH 2029
Query: 227 NECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTG-LGVIRMWADEGSRNSRFQMLF 284
C + + + DG +++ A C + TG IR +D + F F
Sbjct: 2030 RTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/236 (21%), Positives = 94/236 (39%), Gaps = 20/236 (8%)
Query: 62 YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQ 121
Y D C ++I+ + + + F + +E C + ++V DG + +GRFCG
Sbjct: 494 YVHDVNCFWVIKTEMGKVLRITFTF-FRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSS 552
Query: 122 NPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEG 181
P + SS L+ +++ GF+ R+ P C + G G
Sbjct: 553 LPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQ-------------PECGGILTGPYG 599
Query: 182 IVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSS 241
++S DC W + P + F +++ ++C ++++ + DG
Sbjct: 600 SIKSPGY----PGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPL 655
Query: 242 SVEDLKAKFCSTVANDVMLRTG-LGVIRMWADEGSRNSRFQMLF-TSFQEPPCEGN 295
+ L KFC+T + + TG I +D + F + + TS + C GN
Sbjct: 656 YQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSDLRCGGN 711
Score = 60.8 bits (146), Expect = 3e-09
Identities = 48/203 (23%), Positives = 79/203 (38%), Gaps = 25/203 (12%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
GI S YP+ Y ++ C + I A + F + +E C D++E+ DGP
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTF-LAFDLEHHINCSTDYLELYDGPRQ- 1346
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGE-LESMGFSARYNFTPDPDFKDLGALKPL 169
+GR+CG PP ++ L + DG GF ++ +
Sbjct: 1347 ---MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWF---------------V 1388
Query: 170 PACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNEC 229
C E+ G+ G S +C WYIR P S I L D++++ + C
Sbjct: 1389 YGCGGELSGATGSFSSPGFPNRYPPNK----ECIWYIRTDPGSSIQLTIHDFDVEYHSRC 1444
Query: 230 KRNFVAVYDGSSSVEDLKAKFCS 252
+ + +Y G A+ C+
Sbjct: 1445 NFDVLEIYGGPDFHSPRIAQLCT 1467
Score = 60.5 bits (145), Expect = 4e-09
Identities = 32/114 (28%), Positives = 60/114 (52%), Gaps = 3/114 (2%)
Query: 41 CGTWTKHAEGGIFT-SPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 99
CG + + + +F SP +P Y +C ++I+A P +EL IE C +D
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNI-LSLDIESHRTCAYD 2035
Query: 100 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 153
+ +RDG + + CG++ P I+S+G +++I+F +D + GF+A ++
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 2089
Score = 54.3 bits (129), Expect = 3e-07
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 5/102 (4%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG T + + G FTSP YP YP + C +++ A + + + F SI+ +C ++
Sbjct: 3511 CGG-TLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINF-YFISIDDPGDCVQNY 3568
Query: 101 IEVRDGPFGFSPIIGRFCGQQN--PPVIKSSGRFLWIKFFAD 140
+ + DGP SP G +CG P + SS + ++IKF AD
Sbjct: 3569 LTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQ-VFIKFHAD 3609
Score = 52.8 bits (125), Expect = 8e-07
Identities = 59/250 (23%), Positives = 108/250 (43%), Gaps = 34/250 (13%)
Query: 43 TWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE-PSWECKFDHI 101
TWT +SPN P C ++I++ P Q +++ ++++ S +C +++
Sbjct: 3285 TWTPQN----ISSPNSSDPDVPFSICTWVIDSPPHQQVKITV---WALQLTSQDCTQNYL 3337
Query: 102 EVRDGPFGFSPIIGRFCGQQNP--PVIKSSGRFLWIKFFADGELESMGFSARYNFTP-DP 158
+++D P G +FCG+ PV SS + F + + S Y +
Sbjct: 3338 QLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNR 3397
Query: 159 DF-KDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLR 217
D+ K G L+ S G ++ K DC + AP I L
Sbjct: 3398 DYHKAFGNLR-----------SPGWPDNYDNDK----------DCTVTLTAPQNHTISLF 3436
Query: 218 FLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLGVIRMWADEGSR 276
F ++NS EC+ +F+ V +GS+S L K+C T + N V + +R +D +
Sbjct: 3437 FHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTS 3496
Query: 277 NSRFQMLFTS 286
+ +++++TS
Sbjct: 3497 DRGYEIIWTS 3506
Score = 47.4 bits (111), Expect = 3e-05
Identities = 58/261 (22%), Positives = 101/261 (38%), Gaps = 38/261 (14%)
Query: 14 LIILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIE 73
L++ S + +G T TQ ++ CG H++ G SP++P +P + C +
Sbjct: 2779 LVVTFNSDHSLQGGGFYATWNTQ-TLGCGG-IFHSDNGTIRSPHWPQNFPENSRCSWTAI 2836
Query: 74 AAPRQCIELYFDEKYSI-EPSWECKFDHIEVRDGPFGF-SPIIGRFCGQQNP-PVIKSSG 130
+ +E+ FD + I +C+ ++V G ++ CG P PVI S
Sbjct: 2837 THKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSN 2896
Query: 131 RFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMK 190
F + F E + GFSA + + C G G + S K
Sbjct: 2897 TFTAV--FQSQEAPAQGFSASF----------------VSRCGSNFTGPSGYIISPNYPK 2938
Query: 191 EGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQN----SNECKRNFVAVYDGSSSVEDL 246
+ ++C + I A P S + L F+ + ++ + C + V + G S +
Sbjct: 2939 Q----YDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTP 2994
Query: 247 KAKFCS-------TVANDVML 260
A C T+A V+L
Sbjct: 2995 FATVCGDEMPAPLTIAGPVLL 3015
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 116 bits (290), Expect = 6e-26
Identities = 89/314 (28%), Positives = 141/314 (44%), Gaps = 30/314 (9%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + EG I SPNYP Y P +EC++ I + + L F + + IE C +D+
Sbjct: 462 CGGEIRKNEGQI-QSPNYPDDYRPMKECVWKITVSESYHVGLTF-QSFEIERHDNCAYDY 519
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPD--- 157
+EVRDG SP+IGRFCG P I+S+ LW+KF +DG + GF+A + D
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECA 579
Query: 158 -PD--------FKDLGALKPLPACE--FEMG----GSEGIVESIQIMKEGKATA------ 196
PD LG+ + ACE +E+G E + G T
Sbjct: 580 KPDRGGCEQRCLNTLGSYQ--CACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKE 637
Query: 197 -SEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVA 255
+C W + AP + +I ++F +E++ + CK ++V ++ G SS L KFC
Sbjct: 638 YPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEV 697
Query: 256 NDVMLRTGLGV-IRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCNGL 314
+V+ + I +D F+ F S ++ + N H + + +C
Sbjct: 698 PEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCR 757
Query: 315 QNCVYPWDENHCKE 328
V +++ CKE
Sbjct: 758 NGFVLHDNKHDCKE 771
Score = 113 bits (282), Expect = 5e-25
Identities = 67/245 (27%), Positives = 114/245 (46%), Gaps = 18/245 (7%)
Query: 47 HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDG 106
H+ G+ TSPN+P KYP +EC + I A P I+L F E + IE EC +DH+EV DG
Sbjct: 779 HSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSE-FEIEQHQECAYDHLEVFDG 837
Query: 107 PFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGAL 166
SPI+GR CG + P + ++G ++++F +D ++ GF A ++
Sbjct: 838 ETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHS------------- 884
Query: 167 KPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNS 226
C + + + G VDC+W + + S++ L F +E++
Sbjct: 885 ---TECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEE 941
Query: 227 NECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGV-IRMWADEGSRNSRFQMLFT 285
+C ++V ++DG S +FC + + + G V I D+ F + +
Sbjct: 942 ADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYK 1001
Query: 286 SFQEP 290
S + P
Sbjct: 1002 SIRYP 1006
Score = 97.8 bits (242), Expect = 2e-20
Identities = 65/257 (25%), Positives = 113/257 (43%), Gaps = 29/257 (11%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G T+P +P +YPP++ C++ + A + I + F E + +E + CK+D++E+ G
Sbjct: 627 GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKF-EFFELEGNEVCKYDYVEIWSGLSSE 685
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
S + G+FCG + P VI S + I+F +D + GF A + D KD G +
Sbjct: 686 SKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQ--H 743
Query: 171 ACEFEMGGSEGIVESIQIMKEGKATASEA-------------------------VDCKWY 205
C MG + ++ + K EA +C W
Sbjct: 744 ECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWE 803
Query: 206 IRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLG 265
I A P +I L F ++E++ EC + + V+DG + + + C D ++ TG
Sbjct: 804 ISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNK 863
Query: 266 V-IRMWADEGSRNSRFQ 281
+ +R +D + FQ
Sbjct: 864 MFVRFVSDASVQRKGFQ 880
Score = 93.6 bits (231), Expect = 4e-19
Identities = 59/211 (27%), Positives = 98/211 (46%), Gaps = 22/211 (10%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + + G + +SP +P+ YP CI+ + P + I L F + S C +D+
Sbjct: 349 CGETLQESNGNL-SSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTM-DLYKSSLCWYDY 406
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF 160
IEVRDG + SP++GRFCG + P V+ S+ +WI+F + GF+A Y
Sbjct: 407 IEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYE------- 459
Query: 161 KDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLD 220
C E+ +EG ++S + + +C W I + L F
Sbjct: 460 ---------AICGGEIRKNEGQIQSPNYPDDYRPMK----ECVWKITVSESYHVGLTFQS 506
Query: 221 YEMQNSNECKRNFVAVYDGSSSVEDLKAKFC 251
+E++ + C +++ V DG+S L +FC
Sbjct: 507 FEIERHDNCAYDYLEVRDGTSENSPLIGRFC 537
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 60 SKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCG 119
+ YP +C +++ + +EL F + + +E +C +D++E+ DG + +GRFCG
Sbjct: 909 NNYPGQVDCEWLLVSERGSRLELSF-QTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCG 967
Query: 120 QQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD 159
P I S G + I F D + GF RY PD
Sbjct: 968 SGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYPD 1007
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Query: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Query: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
T D C G +ES ++ +DC + I A P+
Sbjct: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
Query: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
Query: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
+ D F + + P E F C+ + + + + N
Sbjct: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Query: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Query: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
T D C G +ES ++ +DC + I A P+
Sbjct: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
Query: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
Query: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
+ D F + + P E F C+ + + + + N
Sbjct: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Query: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Query: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
T D C G +ES ++ +DC + I A P+
Sbjct: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
Query: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
Query: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
+ D F + + P E F C+ + + + + N
Sbjct: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Query: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Query: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
T D C G +ES ++ +DC + I A P+
Sbjct: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
Query: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
Query: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
+ D F + + P E F C+ + + + + N
Sbjct: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Query: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Query: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
T D C G +ES ++ +DC + I A P+
Sbjct: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
Query: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
Query: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
+ D F + + P E F C+ + + + + N
Sbjct: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Query: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Query: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
T D C G +ES ++ +DC + I A P+
Sbjct: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
Query: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
Query: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
+ D F + + P E F C+ + + + + N
Sbjct: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 112 bits (281), Expect = 6e-25
Identities = 75/241 (31%), Positives = 112/241 (46%), Gaps = 38/241 (15%)
Query: 49 EGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPF 108
+ G SPNYP Y P +EC++ I + + L F + + IE C +D++EVRDGP
Sbjct: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTF-QAFEIERHDSCAYDYLEVRDGPT 529
Query: 109 GFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSAR----------------- 151
S +IG FCG + P +KSS LW+KF +DG + GF+A
Sbjct: 530 EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCE 589
Query: 152 ---------YNFTPDPDFKDLGALKPLPACEFEMGG----SEGIVESIQIMKEGKATASE 198
Y DP + +L A K + CE GG G + S KE
Sbjct: 590 HRCVNTLGSYKCACDPGY-ELAADKKM--CEVACGGFITKLNGTITSPGWPKEYPTNK-- 644
Query: 199 AVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDV 258
+C W + AP + +I L+F +E++ ++ CK +FV V G S L +FC + +V
Sbjct: 645 --NCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEV 702
Query: 259 M 259
+
Sbjct: 703 I 703
Score = 106 bits (265), Expect = 5e-23
Identities = 64/237 (27%), Positives = 105/237 (44%), Gaps = 18/237 (7%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G SPN+P KYP REC + I + ++L F+E + IE EC +DH+E+ DGP
Sbjct: 785 GTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQECAYDHLEMYDGPDSL 843
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
+PI+GRFCG + P +SG ++++F++D ++ GF A ++
Sbjct: 844 APILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS----------------T 887
Query: 171 ACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECK 230
C + E + G C W I A + L F +E++ +C
Sbjct: 888 ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCG 947
Query: 231 RNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLG-VIRMWADEGSRNSRFQMLFTS 286
+++ YDG S +FC + + + G +IR D+ F +TS
Sbjct: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 99.4 bits (246), Expect = 7e-21
Identities = 71/278 (25%), Positives = 125/278 (44%), Gaps = 38/278 (13%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 98
V CG + G I TSP +P +YP ++ C++ + A + I L F E + +E + CK+
Sbjct: 618 VACGGFITKLNGTI-TSPGWPKEYPTNKNCVWQVVAPAQYRISLQF-EVFELEGNDVCKY 675
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDP 158
D +EVR G + + GRFCG + P VI S + ++F +D + GF A + D
Sbjct: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDE 735
Query: 159 DFKDLGALKPLPACEFEMGGSEG-----------IVESIQIMKEG----KATASEAV--- 200
KD G C+ E + G + E+ KE K ++ E
Sbjct: 736 CAKDNG------GCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLAS 789
Query: 201 -----------DCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAK 249
+C W I + ++ L F ++E++ EC + + +YDG S+ + +
Sbjct: 790 PNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGR 849
Query: 250 FCSTVANDVMLRTGLGV-IRMWADEGSRNSRFQMLFTS 286
FC + D + +G + +R ++D + FQ + ++
Sbjct: 850 FCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 87.0 bits (214), Expect = 4e-17
Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 22/215 (10%)
Query: 37 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 96
K CG + G F++P +P+ YP C++ I P + I L F + S C
Sbjct: 347 KCPACGETLQDTTGN-FSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSM-DLFKSRLC 404
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
+D++EVRDG + +P++GRFCG + P + S+ LW++F + + GF A Y T
Sbjct: 405 WYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT- 463
Query: 157 DPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYL 216
C +M G ++S + + + +C W I + L
Sbjct: 464 ---------------CGGDMNKDAGQIQSPNYPDDYRPSK----ECVWRITVSEGFHVGL 504
Query: 217 RFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC 251
F +E++ + C +++ V DG + L FC
Sbjct: 505 TFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFC 539
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 60 SKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCG 119
+ YP + C ++I A +EL F + +E +C +D++E DG +P +GRFCG
Sbjct: 911 NNYPSEARCDWVIVAEDGYGVELTF-RTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCG 969
Query: 120 QQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD 159
I S+G L I+F D + GF ARY T D
Sbjct: 970 SGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQD 1009
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 108 bits (269), Expect = 2e-23
Identities = 61/237 (25%), Positives = 111/237 (46%), Gaps = 18/237 (7%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G TSPN+P KYP +EC + I + P ++L F E IE EC +DH+EV DG
Sbjct: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEM-DIESQPECAYDHLEVFDGRDAK 814
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
+P++GRFCG + P + ++G ++++F++D ++ GF A +
Sbjct: 815 APVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH----------------AT 858
Query: 171 ACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECK 230
C ++ + + G VDC+W I A + L F +E++ +C
Sbjct: 859 ECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCG 918
Query: 231 RNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGV-IRMWADEGSRNSRFQMLFTS 286
+++ ++DG S ++C + + + G V ++ +D+ F + +TS
Sbjct: 919 YDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 107 bits (268), Expect = 2e-23
Identities = 95/337 (28%), Positives = 147/337 (43%), Gaps = 45/337 (13%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG K G I SPNYP Y P + CI+ I+ + + L F + + IE C +D+
Sbjct: 435 CGGDVKKDYGHI-QSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDY 492
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD- 159
+EVRDG S +IGR+CG + P IKS+ LW+KF +DG + GF+ NF + D
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDE 550
Query: 160 -------------FKDLGALK-----------PLPACEFEMGG----SEGIVESIQIMKE 191
LG+ K CE GG G + S KE
Sbjct: 551 CSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKE 610
Query: 192 GKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC 251
+C W + AP + +I L+F +E + ++ CK +FV V G ++ L KFC
Sbjct: 611 YPPNK----NCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFC 666
Query: 252 STVANDVMLRTGLGV-IRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCIN--NT 308
+ +V+ + + +D F+ F S + C + C + C+N +
Sbjct: 667 GSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDECSKDNGGCQQD-CVNTFGS 724
Query: 309 LVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTV 345
C V +++ CKE ++T+TSGT+
Sbjct: 725 YECQCRSGFVLHDNKHDCKE---AGCDHKVTSTSGTI 758
Score = 106 bits (264), Expect = 6e-23
Identities = 71/267 (26%), Positives = 120/267 (44%), Gaps = 30/267 (11%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + G I TSP +P +YPP++ CI+ + A + I L FD + E + CK+D
Sbjct: 591 CGGFLTKLNGSI-TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF-FETEGNDVCKYDF 648
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF 160
+EVR G S + G+FCG + P VI S + ++F +D + GF A + D
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
Query: 161 KDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEA--------------------- 199
KD G + C G E S ++ + K EA
Sbjct: 709 KDNGGCQ--QDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDK 766
Query: 200 ----VDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVA 255
+C W I + P ++ L F++ ++++ EC + + V+DG + + +FC +
Sbjct: 767 YPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKK 826
Query: 256 NDVMLRTGLGV-IRMWADEGSRNSRFQ 281
+ +L TG + +R ++D + FQ
Sbjct: 827 PEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 82.8 bits (203), Expect = 7e-16
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 37 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 96
K CG + + G F+SP YP+ Y C++ I P + I L F + S C
Sbjct: 318 KCPACGETLQDSTGN-FSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLC 375
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
+D++EVRDG + +P+ GRFCG + P I S+ LW++F + GF A Y
Sbjct: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE--- 432
Query: 157 DPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYL 216
C ++ G ++S + + + C W I+ + L
Sbjct: 433 -------------AICGGDVKKDYGHIQSPNYPDDYRPSKV----CIWRIQVSEGFHVGL 475
Query: 217 RFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSR 276
F +E++ + C +++ V DG S L ++C D + T + + +GS
Sbjct: 476 TFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSI 535
Query: 277 N 277
N
Sbjct: 536 N 536
Score = 63.9 bits (154), Expect = 3e-10
Identities = 40/140 (28%), Positives = 67/140 (47%), Gaps = 12/140 (8%)
Query: 24 KKGTEKQTTSETQKSVQCGTWTK----HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQC 79
+KG + +E V+ TK HA+ G + YP +C ++I A
Sbjct: 849 RKGFQASHATECGGQVRADVKTKDLYSHAQFG-------DNNYPGGVDCEWVIVAEEGYG 901
Query: 80 IELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFA 139
+EL F + + +E +C +D++E+ DG +P +GR+CG P + S+G + +KF +
Sbjct: 902 VELVF-QTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS 960
Query: 140 DGELESMGFSARYNFTPDPD 159
D + GF RY T D
Sbjct: 961 DDTITKKGFHLRYTSTKFQD 980
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 103 bits (256), Expect = 5e-22
Identities = 77/248 (31%), Positives = 113/248 (45%), Gaps = 37/248 (14%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG K G I SPNYP Y P + CI+ I+ + + L F + + IE C +D+
Sbjct: 435 CGGDVKKDYGHI-QSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDY 492
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD- 159
+EVRDG S +IGR+CG + P IKS+ LW+KF +DG + GF+ NF + D
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDE 550
Query: 160 -------------FKDLGALK-----------PLPACEFEMGG----SEGIVESIQIMKE 191
LG+ K CE GG G + S KE
Sbjct: 551 CSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKE 610
Query: 192 GKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC 251
+C W + AP + +I L+F +E + ++ CK +FV V G ++ L KFC
Sbjct: 611 YPPNK----NCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFC 666
Query: 252 STVANDVM 259
+ +V+
Sbjct: 667 GSEKPEVI 674
Score = 82.8 bits (203), Expect = 7e-16
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 37 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 96
K CG + + G F+SP YP+ Y C++ I P + I L F + S C
Sbjct: 318 KCPACGETLQDSTGN-FSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLC 375
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
+D++EVRDG + +P+ GRFCG + P I S+ LW++F + GF A Y
Sbjct: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE--- 432
Query: 157 DPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYL 216
C ++ G ++S + + + C W I+ + L
Sbjct: 433 -------------AICGGDVKKDYGHIQSPNYPDDYRPSKV----CIWRIQVSEGFHVGL 475
Query: 217 RFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSR 276
F +E++ + C +++ V DG S L ++C D + T + + +GS
Sbjct: 476 TFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSI 535
Query: 277 N 277
N
Sbjct: 536 N 536
Score = 75.9 bits (185), Expect = 9e-14
Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 2/112 (1%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + G I TSP +P +YPP++ CI+ + A + I L FD + E + CK+D
Sbjct: 591 CGGFLTKLNGSI-TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF-FETEGNDVCKYDF 648
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+EVR G S + G+FCG + P VI S + ++F +D + GF A +
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 103 bits (256), Expect = 5e-22
Identities = 77/248 (31%), Positives = 113/248 (45%), Gaps = 37/248 (14%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG K G I SPNYP Y P + CI+ I+ + + L F + + IE C +D+
Sbjct: 435 CGGDVKKDYGHI-QSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF-QSFEIERHDSCAYDY 492
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD- 159
+EVRDG S +IGR+CG + P IKS+ LW+KF +DG + GF+ NF + D
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV--NFFKEVDE 550
Query: 160 -------------FKDLGALK-----------PLPACEFEMGG----SEGIVESIQIMKE 191
LG+ K CE GG G + S KE
Sbjct: 551 CSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKE 610
Query: 192 GKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFC 251
+C W + AP + +I L+F +E + ++ CK +FV V G ++ L KFC
Sbjct: 611 YPPNK----NCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFC 666
Query: 252 STVANDVM 259
+ +V+
Sbjct: 667 GSEKPEVI 674
Score = 82.8 bits (203), Expect = 7e-16
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 37 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 96
K CG + + G F+SP YP+ Y C++ I P + I L F + S C
Sbjct: 318 KCPACGETLQDSTGN-FSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTS-LDLYRSRLC 375
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
+D++EVRDG + +P+ GRFCG + P I S+ LW++F + GF A Y
Sbjct: 376 WYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE--- 432
Query: 157 DPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYL 216
C ++ G ++S + + + C W I+ + L
Sbjct: 433 -------------AICGGDVKKDYGHIQSPNYPDDYRPSKV----CIWRIQVSEGFHVGL 475
Query: 217 RFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSR 276
F +E++ + C +++ V DG S L ++C D + T + + +GS
Sbjct: 476 TFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSI 535
Query: 277 N 277
N
Sbjct: 536 N 536
Score = 75.9 bits (185), Expect = 9e-14
Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 2/112 (1%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + G I TSP +P +YPP++ CI+ + A + I L FD + E + CK+D
Sbjct: 591 CGGFLTKLNGSI-TSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDF-FETEGNDVCKYDF 648
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+EVR G S + G+FCG + P VI S + ++F +D + GF A +
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 102 bits (255), Expect = 7e-22
Identities = 67/237 (28%), Positives = 112/237 (47%), Gaps = 24/237 (10%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKF 98
+CG K G TSP YP Y P +C ++I+A P Q I + F+ + +E +CK+
Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDP 158
D++EV DG G+FCG+ PP + SSG FL+IKF +D E GFS RY
Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEI---- 140
Query: 159 DFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRF 218
K P C G+++S ++ +++C + + AP S+I L F
Sbjct: 141 -------FKRGPECSQNYTTPSGVIKSPGFPEK----YPNSLECTYIVFAPKMSEIILEF 189
Query: 219 LDYEMQNSNE------CKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRM 269
++++ + C+ + + ++DG V ++C +R+ G++ M
Sbjct: 190 ESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQ-KTPGRIRSSSGILSM 245
Score = 80.9 bits (198), Expect = 3e-15
Identities = 53/160 (33%), Positives = 72/160 (45%), Gaps = 20/160 (12%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE------CKFDHIEVR 104
G+ SP +P KYP EC YI+ A I L F E + +EP C++D +E+
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLEIW 214
Query: 105 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLG 164
DG P IGR+CGQ+ P I+SS L + F+ D + GFSA Y+ +D
Sbjct: 215 DGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDF- 273
Query: 165 ALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKW 204
C +G G + S QI TAS W
Sbjct: 274 ------KCMEALGMESGEIHSDQI------TASSQYSTNW 301
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 102 bits (255), Expect = 7e-22
Identities = 67/237 (28%), Positives = 112/237 (47%), Gaps = 24/237 (10%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKF 98
+CG K G TSP YP Y P +C ++I+A P Q I + F+ + +E +CK+
Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDP 158
D++EV DG G+FCG+ PP + SSG FL+IKF +D E GFS RY
Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEI---- 140
Query: 159 DFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRF 218
K P C G+++S ++ +++C + + AP S+I L F
Sbjct: 141 -------FKRGPECSQNYTTPSGVIKSPGFPEK----YPNSLECTYIVFAPKMSEIILEF 189
Query: 219 LDYEMQNSNE------CKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRM 269
++++ + C+ + + ++DG V ++C +R+ G++ M
Sbjct: 190 ESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQ-KTPGRIRSSSGILSM 245
Score = 80.9 bits (198), Expect = 3e-15
Identities = 53/160 (33%), Positives = 72/160 (45%), Gaps = 20/160 (12%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE------CKFDHIEVR 104
G+ SP +P KYP EC YI+ A I L F E + +EP C++D +E+
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLEIW 214
Query: 105 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLG 164
DG P IGR+CGQ+ P I+SS L + F+ D + GFSA Y+ +D
Sbjct: 215 DGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDF- 273
Query: 165 ALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKW 204
C +G G + S QI TAS W
Sbjct: 274 ------KCMEALGMESGEIHSDQI------TASSQYSTNW 301
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 102 bits (255), Expect = 7e-22
Identities = 67/237 (28%), Positives = 112/237 (47%), Gaps = 24/237 (10%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKF 98
+CG K G TSP YP Y P +C ++I+A P Q I + F+ + +E +CK+
Sbjct: 26 KCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR-DCKY 84
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDP 158
D++EV DG G+FCG+ PP + SSG FL+IKF +D E GFS RY
Sbjct: 85 DYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEI---- 140
Query: 159 DFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRF 218
K P C G+++S ++ +++C + + AP S+I L F
Sbjct: 141 -------FKRGPECSQNYTTPSGVIKSPGFPEK----YPNSLECTYIVFAPKMSEIILEF 189
Query: 219 LDYEMQNSNE------CKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRM 269
++++ + C+ + + ++DG V ++C +R+ G++ M
Sbjct: 190 ESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQ-KTPGRIRSSSGILSM 245
Score = 80.9 bits (198), Expect = 3e-15
Identities = 53/160 (33%), Positives = 72/160 (45%), Gaps = 20/160 (12%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE------CKFDHIEVR 104
G+ SP +P KYP EC YI+ A I L F E + +EP C++D +E+
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLEIW 214
Query: 105 DGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLG 164
DG P IGR+CGQ+ P I+SS L + F+ D + GFSA Y+ +D
Sbjct: 215 DGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDF- 273
Query: 165 ALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKW 204
C +G G + S QI TAS W
Sbjct: 274 ------KCMEALGMESGEIHSDQI------TASSQYSTNW 301
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 102 bits (255), Expect = 7e-22
Identities = 88/336 (26%), Positives = 145/336 (43%), Gaps = 37/336 (11%)
Query: 20 SGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQC 79
+ T KG ++ S + +S CG G F+SPNYP YPP+ C++ I+ A
Sbjct: 124 AAGTPKGQQESGVSPSPQST-CGGLLSGPRG-FFSSPNYPDPYPPNTHCVWHIQVATDHA 181
Query: 80 IELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFA 139
I+L E SIE C FD +E+ P G P++ R CG+ PP + ++ L + F +
Sbjct: 182 IQLKI-EALSIESVASCLFDRLELSPEPEG--PLL-RVCGRVPPPTLNTNASHLLVVFVS 237
Query: 140 DGELESMGFSARY-------NFTPDPDFK--DLGALKPLPACEFEMGGSEGIVESIQIMK 190
D +E GF A Y +F+ L L P C+ ++G E+ K
Sbjct: 238 DSSVEGFGFHAWYQAMAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAK 297
Query: 191 ----EGKATASEA--------------VDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRN 232
G T + + C W+I P I L+F ++ ++ +ECK +
Sbjct: 298 FSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFD 357
Query: 233 FVAVYDGSSS-VEDLKAKFCSTVANDVMLRTGLGVIRMW-ADEGSRNSRFQMLFTSFQ-- 288
+V VY+ SSS L +FC ++ + + ++ D G + F + +F
Sbjct: 358 YVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNAT 417
Query: 289 EPPCEGNTFFCHSNMCINNTLVCNGLQNCVYPWDEN 324
E PC + C + C +C+ ++C D+N
Sbjct: 418 ENPCGPSELSCQAGGCKGVQWMCDMWRDCTDGSDDN 453
Score = 31.2 bits (69), Expect = 2.5
Identities = 13/38 (34%), Positives = 18/38 (47%)
Query: 292 CEGNTFFCHSNMCINNTLVCNGLQNCVYPWDENHCKEK 329
C + F C +C+ VC+G NC DE +C K
Sbjct: 260 CAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAK 297
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 92.8 bits (229), Expect = 7e-19
Identities = 64/211 (30%), Positives = 103/211 (48%), Gaps = 28/211 (13%)
Query: 33 SETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEP 92
++ + V+CG A G F+SPN+P YP + EC ++I A + L F + +E
Sbjct: 22 AQAMEGVKCGG-VLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTF-HAFDLEY 79
Query: 93 SWECKFDHIEVRDGPFGFSP----IIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGF 148
C FD +E+ +G SP ++GRFCG+ PP SS + + F +D + S GF
Sbjct: 80 HDTCSFDFLEIYNGA---SPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGF 136
Query: 149 SARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRA 208
SA Y KD+ C + G G++ S E +++C W IRA
Sbjct: 137 SAGYQ-------KDV--------CGGVLTGLSGVLTS----PEYPNNYPNSMECHWVIRA 177
Query: 209 PPRSKIYLRFLDYEMQNSNECKRNFVAVYDG 239
+ + L F+D++++ + EC ++VAV G
Sbjct: 178 AGPAHVKLVFVDFQVEGNEECTYDYVAVLGG 208
Score = 86.3 bits (212), Expect = 6e-17
Identities = 64/221 (28%), Positives = 99/221 (44%), Gaps = 30/221 (13%)
Query: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWE 95
QK V G T G+ TSP YP+ YP EC ++I AA ++L F + + +E + E
Sbjct: 141 QKDVCGGVLT--GLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVD-FQVEGNEE 197
Query: 96 CKFDHIEVRDGPFGFSPIIGR-FCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
C +D++ V GP P G +CG PP + S G L + F +D + GF A Y F
Sbjct: 198 CTYDYVAVLGGP---GPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY-F 253
Query: 155 TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKI 214
+ + C+ G S Q ++ + C W IR PP ++
Sbjct: 254 SGE--------------CQEVYMAMRGNFSSPQY----PSSYPNNIRCHWTIRLPPGYQV 295
Query: 215 YLRFLDYEMQNSNE----CKRNFVAVYDGSSSVEDLKAKFC 251
+ FLD +++ N C + +A +DG+S L +C
Sbjct: 296 KVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWC 336
Score = 65.1 bits (157), Expect = 2e-10
Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSW---ECKFDHIEVRDGP 107
G F+SP YPS YP + C + I P ++++F + EP+ C FDH+ DG
Sbjct: 266 GNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGA 325
Query: 108 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+P++G +CG PP + SS L + D GFS Y
Sbjct: 326 SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
Score = 34.3 bits (77), Expect = 0.29
Identities = 15/55 (27%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 201 DCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVE-DLKAKFCSTV 254
+C W I S + L F ++++ + C +F+ +Y+G+S + +L +FC V
Sbjct: 55 ECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKV 109
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 80.1 bits (196), Expect = 5e-15
Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 13/223 (5%)
Query: 30 QTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYS 89
QT + T+ CG K E G S +P+ YPP++ECI+ I Q + L F +
Sbjct: 26 QTPNYTRPVFLCGGDVK-GESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSF-RVFD 83
Query: 90 IEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFS 149
+E C++D +EV G +GRFCG P + + G + ++ D GF
Sbjct: 84 LELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFL 143
Query: 150 ARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAP 209
Y+ G +F G E ++ ++ + C W+I AP
Sbjct: 144 LWYS----------GRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAP 193
Query: 210 PRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLK-AKFC 251
P I L F ++++ C+ + V+V++G+ S + + KFC
Sbjct: 194 PDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFC 236
Score = 77.8 bits (190), Expect = 2e-14
Identities = 53/143 (37%), Positives = 73/143 (51%), Gaps = 13/143 (9%)
Query: 16 ILHLSGATKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYP-SKYPPDRECIYIIEA 74
+L SG GTE Q CG + A+G + T+PN+P S YPP C + I A
Sbjct: 143 LLWYSGRATSGTEHQF---------CGGRLEKAQGTL-TTPNWPESDYPPGISCSWHIIA 192
Query: 75 APRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF-SPIIGRFCGQQNPPVIKSSGRFL 133
P Q I L F EK+ +EP C++D + V +G S +G+FCG P I S G L
Sbjct: 193 PPDQVIALTF-EKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNEL 251
Query: 134 WIKFFADGELESMGFSARYNFTP 156
++F +D + + GFSA Y P
Sbjct: 252 LVQFVSDLSVTADGFSASYKTLP 274
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 76.3 bits (186), Expect = 7e-14
Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 5/117 (4%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ SPNYP YPP +EC + + +P I L F+ +++EP +D + + DG
Sbjct: 1454 GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNI-FNLEPG----YDFLHIYDGRDSL 1508
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALK 167
SP+IG F G Q P I+SS L++ F +D + + GF Y P D G++K
Sbjct: 1509 SPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIK 1565
Score = 70.1 bits (170), Expect = 5e-12
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 21/165 (12%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ SPNYP Y C+++I A P I L F++ +EP +FD + ++DG
Sbjct: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFND-IDVEP----QFDFLVIKDGATAE 641
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA-----RYNFTPDP------- 158
+P++G F G Q P I SSG ++F D GF+ R+N PDP
Sbjct: 642 APVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGK 701
Query: 159 ---DFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAV 200
D LG+ C+ G++G ++KEG + AV
Sbjct: 702 RFGDSLQLGSSISF-LCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
Score = 65.9 bits (159), Expect = 9e-11
Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 62/291 (21%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKFDHIEVRDG--P 107
GI TSPN+P +Y + C++II A P + I+L F+E + +E +D + V DG
Sbjct: 414 GIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEE-FDLERG----YDTLTVGDGGQD 468
Query: 108 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY--------------- 152
++ G P +I S+ +W+ F DG S+GF A Y
Sbjct: 469 GDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPA 528
Query: 153 ---------------NFTPDPDFKDLG-------------ALKP--LPACEFEMGGSEGI 182
F P F+ +G A KP + +C F G+
Sbjct: 529 YGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGV 588
Query: 183 VESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSS 242
V S ++ + C W I A P S+I+L F D ++ E + +F+ + DG+++
Sbjct: 589 VLSPNYPED----YGNHLHCVWLILARPESRIHLAFNDIDV----EPQFDFLVIKDGATA 640
Query: 243 VEDLKAKFCSTVANDVMLRTG-LGVIRMWADEGSRNSRFQMLFTSFQEPPC 292
+ F + +G + + D + F + FT+F+ C
Sbjct: 641 EAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNEC 691
Score = 61.6 bits (148), Expect = 2e-09
Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 24 KKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELY 83
K+G+ ++ + CG G I SP +P Y C ++IEA P I++
Sbjct: 735 KEGSVVWNSAVLRCEAPCGGHLTSPSGTIL-SPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
Query: 84 FDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGEL 143
FD + E +D +EVRDG +P+IG + G Q P + S+ +L++ F D
Sbjct: 794 FDRFKT-----EVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSH 848
Query: 144 ESMGFSARY 152
+GF RY
Sbjct: 849 SDIGFQLRY 857
Score = 57.4 bits (137), Expect = 3e-08
Identities = 60/246 (24%), Positives = 98/246 (39%), Gaps = 57/246 (23%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 99
+CG +G + SPN+P Y + ECIY I+ P + I+L + + E S + D
Sbjct: 1097 ECGNSVTGTQGTLL-SPNFPVNYNNNHECIYSIQTQPGKGIQL---KARAFELS---EGD 1149
Query: 100 HIEVRDGPFGFSPIIGRFCGQQNPPV-IKSSGRFLWIKFFADGELESMGFSARY------ 152
++V DG + ++G F + V + S+ LW+ F D E S GF +
Sbjct: 1150 VLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELI 1209
Query: 153 -------------------------NFTPDPDFKDLGAL-------------KPLPACEF 174
+F+ DP + G+ +PLP C
Sbjct: 1210 KCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
Query: 175 EMGGSEGIVESIQIMKEG-KATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNF 233
E GG+ S Q++ G A ++C W I A I L FL ++ + ++ R
Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLR-- 1327
Query: 234 VAVYDG 239
++DG
Sbjct: 1328 --IWDG 1331
Score = 56.2 bits (134), Expect = 7e-08
Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 99
QCG + EG + SP +P YP + +C + I + F +S EP+ D
Sbjct: 1967 QCGGTVEEMEG-VILSPGFPGNYPSNMDCSWKIALPVGFGAHIQF-LNFSTEPN----HD 2020
Query: 100 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+IE+R+GP+ S ++GRF G + P + S+ + F +D GF Y
Sbjct: 2021 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/234 (23%), Positives = 83/234 (35%), Gaps = 60/234 (25%)
Query: 43 TWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIE 102
T+ H G SP +P YP C + I A + I+L F + +++E FD +
Sbjct: 27 TFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVF-QSFALEED----FDVLS 81
Query: 103 VRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKD 162
V DGP + R G Q P I S+ L ++ +D + + GF A Y P +
Sbjct: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGN 141
Query: 163 LGALK---------------------------------------------PLPACEFE-- 175
G L PLP+C +
Sbjct: 142 PGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDA 201
Query: 176 ----MGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQN 225
+ G GI+ S E A DC W I A I L F+D+++++
Sbjct: 202 CGGTLRGQSGIISSPHFPSEYHNNA----DCTWTILAELGDTIALVFIDFQLED 251
Score = 54.3 bits (129), Expect = 3e-07
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ S +YP YP + C +++ P I L + S E ++D E+ DGP G
Sbjct: 2366 GVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLS-----EKQYDEFEIFDGPSGQ 2420
Query: 111 SPIIGRFCGQQNPP-VIKSSGRFLWIKFFADGELESMGFSARYN 153
SP++ G + P ++ SS +++++ +D GF RY+
Sbjct: 2421 SPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/267 (20%), Positives = 96/267 (35%), Gaps = 53/267 (19%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 98
V CG G I SP +P Y C++ I I++ + E +W
Sbjct: 1794 VPCGGNLTERRGTIL-SPGFPEPYLNSLNCVWKIVVPEGAGIQIQV-VSFVTEQNW---- 1847
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY-----N 153
D +EV DG ++G F G P ++ S+ L++ F++D + + GF Y +
Sbjct: 1848 DSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907
Query: 154 FTPDPDFKDLG---------------------ALK-----------------PLPACEFE 175
P+P G AL+ P P C +
Sbjct: 1908 SCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQ 1967
Query: 176 MGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVA 235
GG+ +E + + +DC W I P +++FL++ S E +++
Sbjct: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNF----STEPNHDYIE 2023
Query: 236 VYDGSSSVEDLKAKFCSTVANDVMLRT 262
+ +G + +F + +L T
Sbjct: 2024 IRNGPYETSRMMGRFSGSELPSSLLST 2050
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/131 (32%), Positives = 62/131 (47%), Gaps = 11/131 (8%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG T + GI +SP++PS+Y + +C + I A I L F I+ E +D
Sbjct: 202 CGG-TLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVF-----IDFQLEDGYDF 255
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF 160
+EV G G S F G P + SS +L + F +DG GFSA+Y +
Sbjct: 256 LEV-TGTEGSSL---WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIEL 311
Query: 161 KDLGALKPLPA 171
K G +K +P+
Sbjct: 312 KSRG-VKLMPS 321
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 10/123 (8%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKF 98
V CG + G ++ SP +PS Y ++C+++I + L EPS
Sbjct: 2180 VPCGGNITSSNGTVY-SPGFPSPYSSSQDCVWLITVPIGHGVRLNL-SLLQTEPSG---- 2233
Query: 99 DHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFAD---GELESMGFSARYNFT 155
D I + DGP +P +G F ++SS + +KF D G + ++ FSA Y T
Sbjct: 2234 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSA-YPLT 2292
Query: 156 PDP 158
P
Sbjct: 2293 KCP 2295
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 5/125 (4%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 99
+CG + G SP YP+ Y + CI+ IEA I L+F + E D
Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF-----LVFDTEEVHD 1324
Query: 100 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPD 159
+ + DGP ++ G P + S+ + ++F D GF+ +++ +
Sbjct: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATS 1384
Query: 160 FKDLG 164
D G
Sbjct: 1385 CNDPG 1389
Score = 38.1 bits (87), Expect = 0.020
Identities = 59/303 (19%), Positives = 111/303 (36%), Gaps = 64/303 (21%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + + + G I SP +P YP + C +IIE + + + F + E D+
Sbjct: 924 CGGFIQGSSGTIL-SPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH-----LESGHDY 977
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSS--GRF-LWIKFFADGELESMGFSARYN---- 153
+ + + F+ + + G + P I + G F ++F +D + GF+ ++
Sbjct: 978 LLITENG-SFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDL 1036
Query: 154 --------------------------FTPDPDFKDLGALK-------------PLPACEF 174
F+ P ++ G + PLP C
Sbjct: 1037 EPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVA 1096
Query: 175 EMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFV 234
E G S + + + +C + I+ P I L+ +E+ + K
Sbjct: 1097 ECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLK---- 1152
Query: 235 AVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMW----ADEGSRNSRFQMLFTSFQEP 290
VYDG+++ L F + V L + +W D + + F++ F+SF+
Sbjct: 1153 -VYDGNNNSARLLGVFSHSEMMGVTLNSTSS--SLWLDFITDAENTSKGFELHFSSFELI 1209
Query: 291 PCE 293
CE
Sbjct: 1210 KCE 1212
Score = 34.7 bits (78), Expect = 0.22
Identities = 26/140 (18%), Positives = 51/140 (36%), Gaps = 4/140 (2%)
Query: 168 PLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSN 227
PLP CE GG+ + S + DC W I P + L + + S
Sbjct: 2174 PLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG 2233
Query: 228 ECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSF 287
+ F+ ++DG F ++A + + V+ + + + F + F+++
Sbjct: 2234 D----FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAY 2289
Query: 288 QEPPCEGNTFFCHSNMCINN 307
C T ++ + N
Sbjct: 2290 PLTKCPPPTILPNAEVVTEN 2309
Score = 33.9 bits (76), Expect = 0.38
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ SPNYP Y + C+Y + P+ + F + + D +EV DG
Sbjct: 1628 GVVLSPNYPQNYTSGQICLYFV-TVPKDYV--VFGQFAFFHTALN---DVVEVHDGHSQH 1681
Query: 111 SPIIGRFCGQQNPPVIK-SSGRFLWIKFFADGELESMGFSARYNFTP 156
S ++ G + ++ + IKF A G + GF Y P
Sbjct: 1682 SRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVP 1728
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 75.1 bits (183), Expect = 1e-13
Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
Query: 48 AEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGP 107
A G+ P +P Y C +IIEA P I++ FD + E +D +EVRDGP
Sbjct: 765 ASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQT-----EVNYDTLEVRDGP 819
Query: 108 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY-NFTPDPDFKDLGAL 166
SP+IG + G Q P + S+G F+++ F D S+GF Y + T + D L
Sbjct: 820 ASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESD----SCL 875
Query: 167 KP-LPACEFEMGGSEGIVESIQIMKEGKATASE 198
P +P GG GI ++ + T S+
Sbjct: 876 DPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSD 908
Score = 73.9 bits (180), Expect = 3e-13
Identities = 64/276 (23%), Positives = 109/276 (39%), Gaps = 54/276 (19%)
Query: 48 AEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGP 107
A GI SPNYP +Y + C+++I + P I L F++ + +EP +FD + V+D
Sbjct: 591 ASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFND-FDVEP----QFDFLAVKDDG 645
Query: 108 FGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY-----NFTPDPDFK- 161
++G F G + P + SSG + ++F +D GF+ Y N DP
Sbjct: 646 ISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPI 705
Query: 162 -------------------DLGALK--------------------PLPACEFEMGGSEGI 182
D G +K +P CE GG
Sbjct: 706 NGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTA 765
Query: 183 VESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSS 242
+ + +++ C+W I A P I + F ++ E + + V DG +S
Sbjct: 766 SSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQ----TEVNYDTLEVRDGPAS 821
Query: 243 VEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNS 278
L ++ T A ++ TG + ++ + SR+S
Sbjct: 822 SSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSS 857
Score = 71.2 bits (173), Expect = 2e-12
Identities = 37/106 (34%), Positives = 59/106 (55%), Gaps = 5/106 (4%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ SPNYP YPP +EC + ++ P I L F + +++EPS +D + + +G
Sbjct: 1461 GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIF-KSFNMEPS----YDFLHIYEGEDSN 1515
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
SP+IG + G Q P I+SSG L++ F +D + GF+ + P
Sbjct: 1516 SPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKP 1561
Score = 66.2 bits (160), Expect = 7e-11
Identities = 64/297 (21%), Positives = 102/297 (34%), Gaps = 72/297 (24%)
Query: 50 GGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFG 109
GG+ SP +P YP + +C + I + F + S E D +E+++GP+
Sbjct: 1983 GGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQF-----LNFSTEANHDFLEIQNGPYH 2037
Query: 110 FSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF-----TPDPDFKDLG 164
SP+IG+F G P + S+ I F++D GF Y PDP G
Sbjct: 2038 TSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNG 2097
Query: 165 AL--------------------------------------KPLPACEFEMG--------- 177
+ P P C+ G
Sbjct: 2098 YMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNGT 2157
Query: 178 -GSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAV 236
S G + I+K DC W I PP +Y+ F + + N+ ++AV
Sbjct: 2158 IYSPGFPDEYPILK----------DCIWLITVPPGHGVYINFTLLQTEAVND----YIAV 2203
Query: 237 YDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCE 293
+DG F A + + V+ + + S F + F +FQ C+
Sbjct: 2204 WDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQ 2260
Score = 59.7 bits (143), Expect = 6e-09
Identities = 69/272 (25%), Positives = 99/272 (36%), Gaps = 62/272 (22%)
Query: 19 LSGATKK----GTEKQTTSETQKSV-QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIE 73
L GATK G + ++ + V +CG K EG + SPN+PS Y + ECIY IE
Sbjct: 1078 LEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLL-SPNFPSNYDNNHECIYKIE 1136
Query: 74 AAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFC-GQQNPPVIKSSGRF 132
+ I L E D ++V DG S +G F + ++ S+
Sbjct: 1137 TEAGKGIHLRTRSFQLFEG------DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNH 1190
Query: 133 LWIKFFADGELESMGFSARYNF-----TPDPDFKDLGAL--------------------- 166
LW++F +G GF Y DP + G
Sbjct: 1191 LWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYA 1250
Query: 167 ------------------KPLPACEFEMGGSEGIVESIQIMKEG-KATASEAVDCKWYIR 207
KPLP+C E GG S +I+ G A + C W I
Sbjct: 1251 MHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIE 1310
Query: 208 APPRSKIYLRFLDYEMQNSNECKRNFVAVYDG 239
A P I L F+ ++ E + + V+DG
Sbjct: 1311 ADPGKTISLHFIVFD----TEMAHDILKVWDG 1338
Score = 57.8 bits (138), Expect = 2e-08
Identities = 58/308 (18%), Positives = 114/308 (37%), Gaps = 58/308 (18%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G SP YP Y + CI+ I I++ ++ E +W D +E+ DG
Sbjct: 1812 GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVIS-FATEQNW----DSLEIHDGGDVT 1866
Query: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY------------------ 152
+P +G F G P ++ S+ L++ F +D + + GF Y
Sbjct: 1867 APRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSI 1926
Query: 153 ------------NFTPDPDFKDLGALK-------------PLPACEFEMGGSEGIVESIQ 187
+F +P + G P P C GG+ + +
Sbjct: 1927 KIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVI 1986
Query: 188 IMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLK 247
+ + +DC W I P +++FL++ S E +F+ + +G +
Sbjct: 1987 LSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNF----STEANHDFLEIQNGPYHTSPMI 2042
Query: 248 AKFCSTVANDVML-RTGLGVIRMWADEGSRNSRFQMLFTSFQ-----EPPCEGNTFFCHS 301
+F T +L T +I ++D F++ + +++ +PP N + +S
Sbjct: 2043 GQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMINS 2102
Query: 302 NMCINNTL 309
+ + ++
Sbjct: 2103 DYSVGQSV 2110
Score = 56.6 bits (135), Expect = 5e-08
Identities = 66/287 (22%), Positives = 107/287 (37%), Gaps = 67/287 (23%)
Query: 40 QCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFD 99
+CG A G SP YP+ Y + C +IIEA P + I L+F I E D
Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHF-----IVFDTEMAHD 1331
Query: 100 HIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN------ 153
++V DGP ++ + G P I S+ L ++F +D + GFS +++
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 154 ------------------------FTPDPDFKDLGALK-------------PLP-----A 171
F DP ++ G K P P A
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 172 CEFEMGGSEGIVES---IQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNE 228
C + G G++ S Q GK +C W ++ P I L F + M+ S +
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGK-------ECDWRVKVNPDFVIALIFKSFNMEPSYD 1504
Query: 229 CKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGS 275
F+ +Y+G S L + + A + + +G + + + S
Sbjct: 1505 ----FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDAS 1547
Score = 55.1 bits (131), Expect = 2e-07
Identities = 69/301 (22%), Positives = 116/301 (38%), Gaps = 63/301 (20%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSWECKFD 99
CG+ G+ TSPNYP +Y + C+++I P + I+L F+E + +E +D
Sbjct: 412 CGS-NLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEE-FELERG----YD 465
Query: 100 HIEVRD-GPFGFS-PIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP- 156
+ V D G G + ++ G P +I S +W+ +D + S GF A Y
Sbjct: 466 TLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEK 525
Query: 157 ----DPDFKDLG--------------------------------------ALKP--LPAC 172
DP G KP + +C
Sbjct: 526 GGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSC 585
Query: 173 EFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRN 232
F S GI+ S +E ++C W I + P S+I+L F D+++ E + +
Sbjct: 586 FFNFTASSGIILSPNYPEE----YGNNMNCVWLIISEPGSRIHLIFNDFDV----EPQFD 637
Query: 233 FVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGV-IRMWADEGSRNSRFQMLFTSFQEPP 291
F+AV D S + F + +G V + +D + F + +T+F +
Sbjct: 638 FLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNE 697
Query: 292 C 292
C
Sbjct: 698 C 698
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/120 (31%), Positives = 51/120 (42%), Gaps = 6/120 (5%)
Query: 37 KSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWEC 96
K CG + G I SP +P YP C +II R I+L F +++E
Sbjct: 28 KGQNCGGLVQGPNGTI-ESPGFPHGYPNYANCTWIIITGERNRIQLSF-HTFALEED--- 82
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
FD + V DG + R G Q P I S+G L + F D + + GF A Y P
Sbjct: 83 -FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLP 141
Score = 46.2 bits (108), Expect = 7e-05
Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 12/106 (11%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G+ SP YP Y + C + I+ P I ++ D S E +FD +EV DG G
Sbjct: 2331 GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQS-----EKQFDALEVFDGSSGQ 2385
Query: 111 SPII----GRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
SP++ G Q N S L++++ D GF RY
Sbjct: 2386 SPLLVVLSGNHTEQSN---FTSRSNQLYLRWSTDHATSKKGFKIRY 2428
Score = 44.7 bits (104), Expect = 2e-04
Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + ++ G SP +P +YP ++CI++I P + + F + E D+
Sbjct: 2147 CG-YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQT-----EAVNDY 2200
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFAD 140
I V DGP SP +G F G SS + +KF +D
Sbjct: 2201 IAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
Score = 42.7 bits (99), Expect = 8e-04
Identities = 66/304 (21%), Positives = 109/304 (35%), Gaps = 66/304 (21%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + + G + SP +P YP C + IE + + +++ F + +E S D+
Sbjct: 931 CGGYIQGKSGTVL-SPGFPDFYPNSLNCTWTIEVSHGKGVQMIF-HTFHLESS----HDY 984
Query: 101 IEV-RDGPFGFSPIIGRFCGQQNPPVIKSS--GRF-LWIKFFADGELESMGFS---ARYN 153
+ + DG FS + R G P IK+ G F ++F +D + GF+ + Y+
Sbjct: 985 LLITEDG--SFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042
Query: 154 FTPDPD---------------------------FKDLGALK-------------PLPACE 173
P D ++ GA K PLP C
Sbjct: 1043 LEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
Query: 174 FEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNF 233
E G S E + + +C + I I+LR +++ + K
Sbjct: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK--- 1159
Query: 234 VAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNS----RFQMLFTSFQE 289
VYDG S F ++L + +W + + S FQ+ +TSF
Sbjct: 1160 --VYDGKDSSSRPLGTFTKNELLGLILNSTSN--HLWLEFNTNGSDTDQGFQLTYTSFDL 1215
Query: 290 PPCE 293
CE
Sbjct: 1216 VKCE 1219
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/131 (25%), Positives = 59/131 (45%), Gaps = 11/131 (8%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + I +SP++PS+Y + +C + I A P I L F + + +E ++ F
Sbjct: 208 CGGTLRGTSSSI-SSPHFPSEYENNADCTWTILAEPGDTIALVFTD-FQLEEGYD--FLE 263
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF 160
I + P + G P + SS +L + F +D GF+A++ +
Sbjct: 264 ISGTEAPSIW------LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
Query: 161 KDLGALKPLPA 171
K G +K LP+
Sbjct: 318 KSRG-VKMLPS 327
Score = 29.3 bits (64), Expect = 9.4
Identities = 24/111 (21%), Positives = 43/111 (38%), Gaps = 15/111 (13%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIEL----YFDEKYSIEPSWECKFDHIEVRDG 106
G+ SPNYP Y + C+Y I P++ + YF + D E+ DG
Sbjct: 1635 GVVLSPNYPHNYTAGQICLYSI-TVPKEFVVFGQFAYFQTALN---------DLAELFDG 1684
Query: 107 PFGFSPIIGRFCGQQNPPVIK-SSGRFLWIKFFADGELESMGFSARYNFTP 156
+ ++ G + + ++ + ++F A + GF Y P
Sbjct: 1685 THAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVP 1735
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/207 (26%), Positives = 89/207 (42%), Gaps = 19/207 (9%)
Query: 49 EGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPF 108
E G S +P YPP+ +C + I + + L F +E C++D ++V +G
Sbjct: 40 ESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNF-RFIDLESDNLCRYDFVDVYNGHA 98
Query: 109 GFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKD--LGAL 166
IGRFCG P + SSG + ++ +D GF A ++ + D G L
Sbjct: 99 N-GQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGL 157
Query: 167 KPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNS 226
P+ F+ V C W+I AP I L+F ++++
Sbjct: 158 LDRPSGSFKTPNWPD------------RDYPAGVTCVWHIVAPKNQLIELKFEKFDVERD 205
Query: 227 NECKRNFVAVYDGSSSVEDLK--AKFC 251
N C+ ++VAV++G V D + K+C
Sbjct: 206 NYCRYDYVAVFNG-GEVNDARRIGKYC 231
Score = 64.3 bits (155), Expect = 3e-10
Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 51 GIFTSPNYPSK-YPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEV-RDGPF 108
G F +PN+P + YP C++ I A Q IEL F EK+ +E C++D++ V G
Sbjct: 163 GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKF-EKFDVERDNYCRYDYVAVFNGGEV 221
Query: 109 GFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTP 156
+ IG++CG P I S L I+F +D L + GF Y F P
Sbjct: 222 NDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRP 269
>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
sapiens]
Length = 380
Score = 70.9 bits (172), Expect = 3e-12
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE--PSWEC 96
V+C G+ TSP++P+ YP EC+Y IE + L F++ + IE P C
Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+D+I+++ GP ++G FCG++ P I + + I F +D E+ G+ Y
Sbjct: 243 PYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G SP YP YP D E + I I+LYF +++E S+ C++D+++V
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSYLCEYDYVKVETE---- 83
Query: 111 SPIIGRFCG------QQNP--PVIKSSGRFLWIKFFAD--GELESMGFSARY 152
++ FCG +Q P V+ S G F+ I F +D E GF A Y
Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHY 135
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 70.9 bits (172), Expect = 3e-12
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE--PSWEC 96
V+C G+ TSP++P+ YP EC+Y IE + L F++ + IE P C
Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+D+I+++ GP ++G FCG++ P I + + I F +D E+ G+ Y
Sbjct: 243 PYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G SP YP YP D E + I I+LYF +++E S+ C++D+++V
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSYLCEYDYVKVETE---- 83
Query: 111 SPIIGRFCG------QQNP--PVIKSSGRFLWIKFFAD--GELESMGFSARY 152
++ FCG +Q P V+ S G F+ I F +D E GF A Y
Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHY 135
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 70.9 bits (172), Expect = 3e-12
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 39 VQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIE--PSWEC 96
V+C G+ TSP++P+ YP EC+Y IE + L F++ + IE P C
Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242
Query: 97 KFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
+D+I+++ GP ++G FCG++ P I + + I F +D E+ G+ Y
Sbjct: 243 PYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
G SP YP YP D E + I I+LYF +++E S+ C++D+++V
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYF-MHFNLESSYLCEYDYVKVETE---- 83
Query: 111 SPIIGRFCG------QQNP--PVIKSSGRFLWIKFFAD--GELESMGFSARY 152
++ FCG +Q P V+ S G F+ I F +D E GF A Y
Sbjct: 84 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHY 135
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 70.5 bits (171), Expect = 4e-12
Identities = 40/123 (32%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + G F+SP YP YP + +C++ IE + + F + ++ C +D+
Sbjct: 1257 CGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDY 1312
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF 160
IEV DGP+ SP+I R C SS F+ I+F +D + GF A Y +P D
Sbjct: 1313 IEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDS 1371
Query: 161 KDL 163
+L
Sbjct: 1372 TNL 1374
Score = 69.3 bits (168), Expect = 8e-12
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 3/126 (2%)
Query: 31 TTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSI 90
TT+ + S CG + +A G F+SP+YP+ YP + +C++ IE I L F +
Sbjct: 1005 TTTTARPSSNCGGFLFYASG-TFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKL 1062
Query: 91 EPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA 150
E C FD++E+ DG S ++G+ C + SS + I F +D ++ GF A
Sbjct: 1063 EAHHNCSFDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLA 1121
Query: 151 RYNFTP 156
YN P
Sbjct: 1122 WYNSFP 1127
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/86 (23%), Positives = 36/86 (41%)
Query: 202 CKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLR 261
C W I +I L F + +++ + C ++V ++DGS + L K C+
Sbjct: 1041 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSS 1100
Query: 262 TGLGVIRMWADEGSRNSRFQMLFTSF 287
I +D +N+ F + SF
Sbjct: 1101 YNRMTIHFRSDISFQNTGFLAWYNSF 1126
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 70.5 bits (171), Expect = 4e-12
Identities = 40/123 (32%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Query: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
CG + G F+SP YP YP + +C++ IE + + F + ++ C +D+
Sbjct: 1383 CGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRD---VQLEGGCNYDY 1438
Query: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF 160
IEV DGP+ SP+I R C SS F+ I+F +D + GF A Y +P D
Sbjct: 1439 IEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDS 1497
Query: 161 KDL 163
+L
Sbjct: 1498 TNL 1500
Score = 69.3 bits (168), Expect = 8e-12
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 3/126 (2%)
Query: 31 TTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSI 90
TT+ + S CG + +A G F+SP+YP+ YP + +C++ IE I L F +
Sbjct: 1131 TTTTARPSSNCGGFLFYASG-TFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGF-SNLKL 1188
Query: 91 EPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSA 150
E C FD++E+ DG S ++G+ C + SS + I F +D ++ GF A
Sbjct: 1189 EAHHNCSFDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLA 1247
Query: 151 RYNFTP 156
YN P
Sbjct: 1248 WYNSFP 1253
Score = 34.3 bits (77), Expect = 0.29
Identities = 20/86 (23%), Positives = 36/86 (41%)
Query: 202 CKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLR 261
C W I +I L F + +++ + C ++V ++DGS + L K C+
Sbjct: 1167 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSS 1226
Query: 262 TGLGVIRMWADEGSRNSRFQMLFTSF 287
I +D +N+ F + SF
Sbjct: 1227 YNRMTIHFRSDISFQNTGFLAWYNSF 1252
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,934,225
Number of Sequences: 37866
Number of extensions: 1001681
Number of successful extensions: 3019
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 2226
Number of HSP's gapped (non-prelim): 573
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.