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Search of human proteins with 11342676
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11342676 thyroid hormone receptor interactor 10 [Homo
sapiens]
(545 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens] 1093 0.0
gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens] 601 e-172
gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens] 601 e-172
gi|38524622 formin binding protein 1 [Homo sapiens] 550 e-156
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 80 4e-15
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens] 73 6e-13
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens] 73 8e-13
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 59 9e-09
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 57 6e-08
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 57 6e-08
gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens] 56 7e-08
gi|189491774 nephrocystin 1 isoform 2 [Homo sapiens] 56 7e-08
gi|46397398 nephrocystin 1 isoform 1 [Homo sapiens] 56 7e-08
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 56 7e-08
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 55 2e-07
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 55 2e-07
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 55 2e-07
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 55 2e-07
gi|20149528 proline-serine-threonine phosphatase interacting pro... 55 2e-07
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 52 1e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 52 1e-06
gi|148746195 trichohyalin [Homo sapiens] 52 1e-06
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 49 2e-05
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 49 2e-05
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 49 2e-05
gi|24308229 protein kinase C and casein kinase substrate in neur... 49 2e-05
gi|189491778 nephrocystin 1 isoform 4 [Homo sapiens] 48 3e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 47 3e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 47 3e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 4e-05
>gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens]
Length = 545
Score = 1093 bits (2828), Expect = 0.0
Identities = 545/545 (100%), Positives = 545/545 (100%)
Query: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK 60
MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK
Sbjct: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK 60
Query: 61 DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG 120
DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG
Sbjct: 61 DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG 120
Query: 121 RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS 180
RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS
Sbjct: 121 RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS 180
Query: 181 HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE 240
HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE
Sbjct: 181 HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE 240
Query: 241 VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL 300
VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL
Sbjct: 241 VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL 300
Query: 301 GTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQK 360
GTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQK
Sbjct: 301 GTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQK 360
Query: 361 EVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVL 420
EVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVL
Sbjct: 361 EVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVL 420
Query: 421 SNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEE 480
SNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEE
Sbjct: 421 SNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEE 480
Query: 481 EPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYL 540
EPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYL
Sbjct: 481 EPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYL 540
Query: 541 RVTLN 545
RVTLN
Sbjct: 541 RVTLN 545
>gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]
Length = 551
Score = 601 bits (1549), Expect = e-172
Identities = 300/548 (54%), Positives = 402/548 (73%), Gaps = 12/548 (2%)
Query: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK 60
M WGTELWDQF+ L++HTQWG+D L+RY KFVKER E+EQ YAKQLR+LVKKY PKR +K
Sbjct: 1 MSWGTELWDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSK 60
Query: 61 DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG 120
D+ E +F+ +F IL E+ND+AGQRE+VAE ++ RV EL +Y+ ++K ERKMH QEG
Sbjct: 61 DE-EPRFTSCVAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEG 119
Query: 121 RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS 180
R+AQQ L+ +KQ++NSK+KFER+CREAEKA Q+ ERLD D NATKADVEKAKQQ +LR+
Sbjct: 120 RKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDNDTNATKADVEKAKQQLNLRT 179
Query: 181 HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE 240
HMA+E+KNEYAAQLQ FN +Q ++ +PQI+ +LQ+MDERR +L Y +++E +
Sbjct: 180 HMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERK 239
Query: 241 VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL 300
V+PII+KCLEGM +AA +VD + DS ++++ KSGF PGD FED+SQ + R SD ++
Sbjct: 240 VIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTI 299
Query: 301 GTPSDGRPELRGP---GRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRE 357
++ G+++ K W FGKK K EDFSHLPPEQ+RK+LQQ+++E +RE
Sbjct: 300 SASKQESGKMDAKTTVGKAKGKLWLFGKKPKGPALEDFSHLPPEQRRKKLQQRIDELNRE 359
Query: 358 LQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAES 417
LQKE DQ++AL KMKDVYEK PQMGDP SL+P++AET++NI+RL++E+ K EAWL+E E
Sbjct: 360 LQKESDQKDALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEG 419
Query: 418 RVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDED 477
+ RGD RH+ + + +S S + D + PP + + EFD++
Sbjct: 420 KT-GGRGD--RRHSSDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGH----HNEFDDE 472
Query: 478 FE-EEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVP 536
FE ++P IGHC AIY F+G +EGT++M EGE L ++EEDKGDGWTR RR+ G EGYVP
Sbjct: 473 FEDDDPLPAIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVP 532
Query: 537 TSYLRVTL 544
TSY+ VTL
Sbjct: 533 TSYIDVTL 540
>gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]
Length = 547
Score = 601 bits (1549), Expect = e-172
Identities = 300/548 (54%), Positives = 402/548 (73%), Gaps = 12/548 (2%)
Query: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK 60
M WGTELWDQF+ L++HTQWG+D L+RY KFVKER E+EQ YAKQLR+LVKKY PKR +K
Sbjct: 1 MSWGTELWDQFDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSK 60
Query: 61 DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG 120
D+ E +F+ +F IL E+ND+AGQRE+VAE ++ RV EL +Y+ ++K ERKMH QEG
Sbjct: 61 DE-EPRFTSCVAFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEG 119
Query: 121 RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS 180
R+AQQ L+ +KQ++NSK+KFER+CREAEKA Q+ ERLD D NATKADVEKAKQQ +LR+
Sbjct: 120 RKAQQYLDMCWKQMDNSKKKFERECREAEKAQQSYERLDNDTNATKADVEKAKQQLNLRT 179
Query: 181 HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE 240
HMA+E+KNEYAAQLQ FN +Q ++ +PQI+ +LQ+MDERR +L Y +++E +
Sbjct: 180 HMADENKNEYAAQLQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFADSERK 239
Query: 241 VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL 300
V+PII+KCLEGM +AA +VD + DS ++++ KSGF PGD FED+SQ + R SD ++
Sbjct: 240 VIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDYSQHIYRTISDGTI 299
Query: 301 GTPSDGRPELRGP---GRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRE 357
++ G+++ K W FGKK K EDFSHLPPEQ+RK+LQQ+++E +RE
Sbjct: 300 SASKQESGKMDAKTTVGKAKGKLWLFGKKPKGPALEDFSHLPPEQRRKKLQQRIDELNRE 359
Query: 358 LQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAES 417
LQKE DQ++AL KMKDVYEK PQMGDP SL+P++AET++NI+RL++E+ K EAWL+E E
Sbjct: 360 LQKESDQKDALNKMKDVYEKNPQMGDPGSLQPKLAETMNNIDRLRMEIHKNEAWLSEVEG 419
Query: 418 RVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDED 477
+ RGD RH+ + + +S S + D + PP + + EFD++
Sbjct: 420 KT-GGRGD--RRHSSDINHLVTQGRESPEGSYTDDANQEVRGPPQQHGH----HNEFDDE 472
Query: 478 FE-EEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVP 536
FE ++P IGHC AIY F+G +EGT++M EGE L ++EEDKGDGWTR RR+ G EGYVP
Sbjct: 473 FEDDDPLPAIGHCKAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVP 532
Query: 537 TSYLRVTL 544
TSY+ VTL
Sbjct: 533 TSYIDVTL 540
>gi|38524622 formin binding protein 1 [Homo sapiens]
Length = 617
Score = 550 bits (1418), Expect = e-156
Identities = 287/616 (46%), Positives = 408/616 (66%), Gaps = 76/616 (12%)
Query: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK 60
M WGTELWDQF+ LE+HTQWG+D+L++Y+KFVKERTE+E +YAKQLR+L KKY PK+ +K
Sbjct: 1 MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSK 60
Query: 61 DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG 120
++ E K++ ++F+ L E+ND+AGQ E+++EN++ ++ ++L +Y QE+KQERK +F +G
Sbjct: 61 EEEEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDG 120
Query: 121 RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS 180
R+AQQ +E +KQLE+SKR+FERDC+EA++A Q E++D DIN TKADVEKA+QQA +R
Sbjct: 121 RKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRH 180
Query: 181 HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE 240
MAE+SK +Y++ LQ+FN +Q +Y + +P IF K+Q+M+ERR R+G +E + +
Sbjct: 181 QMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQ 240
Query: 241 VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL 300
V+PII KCL+G+ AA ++D KNDS ++IE +KSGF PGD+EFED++QPM R SD+SL
Sbjct: 241 VIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSL 300
Query: 301 -GTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLP-------------------P 340
+ +G+P+L+ G+S+ K WPF KKNK + H P P
Sbjct: 301 SNSRGEGKPDLKFGGKSKGKLWPFIKKNKLMSLLTSPHQPPPPPPASASPSAVPNGPQSP 360
Query: 341 EQQRKRLQQQL------------------------------------EERSREL------ 358
+QQ++ L + E+R ++L
Sbjct: 361 KQQKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGATPEDFSNLPPEQRRKKLQQKVDE 420
Query: 359 -----QKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLA 413
QKE+DQR+A+ KMKDVY K PQMGDPASL+ ++AE NIE+L++E QK+EAWLA
Sbjct: 421 LNKEIQKEMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVSQNIEKLRVETQKFEAWLA 480
Query: 414 EAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKE---SSEEPPSEESQDTPI 470
E E R L R + R + D + PP + N+ +QD + S E S+ES+ +
Sbjct: 481 EVEGR-LPARSEQARRQSGLYD--SQNPP--TVNNCAQDRESPDGSYTEEQSQESEMKVL 535
Query: 471 YTEFDEDF-EEEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKE 529
T+FD++F +EEP IG C A+Y FEG +EGTIS+ EGE L ++EEDKGDGWTR+RR E
Sbjct: 536 ATDFDDEFDDEEPLPAIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNE 595
Query: 530 GGEGYVPTSYLRVTLN 545
EGYVPTSY+ V L+
Sbjct: 596 DEEGYVPTSYVEVCLD 611
>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
Length = 740
Score = 80.5 bits (197), Expect = 4e-15
Identities = 118/564 (20%), Positives = 223/564 (39%), Gaps = 88/564 (15%)
Query: 9 DQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLP------KRPAKDD 62
+Q L+ Q DLL+ F +++ +E+ YA+ ++ L +YL K ++D
Sbjct: 20 EQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGMQKLASQYLKRDWPGVKADDRND 79
Query: 63 PESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRR 122
S + +SF++ +V A R + EN + +Q+ K + +
Sbjct: 80 YRSMYPVWKSFLEGTMQV---AQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTK 136
Query: 123 AQQQLENGFKQLENSKRKFERDCREAEKAAQTAE--------RLDQDINATKADVEKAKQ 174
Q +L+ K L K+K+ + A + A+ I+ KA V+ +
Sbjct: 137 IQTELQETVKDLAKGKKKYFETEQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKAR 196
Query: 175 QAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLL 234
++ S A ++N+Y L N Q +Y + + I ++ +D L
Sbjct: 197 RSECNSK-ATHARNDYLLTLAAANAHQDRYYQTDLVNI---MKALDGNVYDHLKDYLIAF 252
Query: 235 SEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSG-FARPGDVEFEDFSQPMNR 293
S ELE + + + N+ D ++ + L ++ F +P +F+ +R
Sbjct: 253 SRTELETCQAVQNTFQFL--LENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSR 310
Query: 294 APSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLE- 352
+S GT + L R R +++K +V ++R+ LE
Sbjct: 311 Q-LESETGTTEEH--SLNKEARKWATR--VAREHKNIV-----------HQQRVLNDLEC 354
Query: 353 ------ERSR-ELQKEVDQ-REALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLE 404
E+SR EL++++D+ RE ++K + + K + ++ LK
Sbjct: 355 HGAAVSEQSRAELEQKIDEARENIRKAEIIKLKAE----------------ARLDLLKQI 398
Query: 405 VQKYEAWLAEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEE 464
+ WL A ++V+ + R ARPP +SN +E EE
Sbjct: 399 GVSVDTWLKSAMNQVMEELENE--RWARPPAV--------TSNGTLHSLNADTEREEGEE 448
Query: 465 SQDTPIYTEFDEDFEEEPTSPIGH-------CVAIYHFEGSSEGTISMAEGEDLSLMEED 517
+D + F++ +SP G C +Y ++ S +++ E E L ++E+
Sbjct: 449 FEDNM------DVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDG 502
Query: 518 KGDGWTRVRRKEGGEGYVPTSYLR 541
+ W + R K G GYVP YL+
Sbjct: 503 DMEDWVKARNKVGQVGYVPEKYLQ 526
>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
Length = 690
Score = 73.2 bits (178), Expect = 6e-13
Identities = 117/562 (20%), Positives = 214/562 (38%), Gaps = 87/562 (15%)
Query: 9 DQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKD-DPESKF 67
+Q +L+ Q DLL+ + K+R +E+ Y + L+ L +L + + + +S+
Sbjct: 20 EQLSILQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKREGHRSGEMDSRG 79
Query: 68 SQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQL 127
+ L + GQ L A + + + ++E Q + + +RAQ ++
Sbjct: 80 RTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTGRSAKE--QVLRKGTENLQRAQAEV 137
Query: 128 ENGFKQLENSKRKFERDCR----EAEKAAQTAERL---DQDINATKADVEKAKQ----QA 176
++L S++ + + R EKAA RL D I ++ ++K Q+
Sbjct: 138 LQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQS 197
Query: 177 HLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKL-QDMDERRATRLGAGYGLLS 235
S + ++NEY L N H+Y ++P + L ++ E L + LS
Sbjct: 198 AQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTS----LS 253
Query: 236 EAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAP 295
ELE + V++E G V +E + + P
Sbjct: 254 HTELEA-----------------------AEVILEHAHRGEQTTSQVSWEQDLKLFLQEP 290
Query: 296 SDSSLGTPSDGRPELRGPGRSRTKRWPF-GKKNKTVVTEDFSHLPPEQQRK--------R 346
S P +P G + W G K+ + ++ L R R
Sbjct: 291 GVFSPTPPQQFQPA--GTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHR 348
Query: 347 LQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQ 406
+ Q+LE+R +++ +REA S+E ++ E +I R ++
Sbjct: 349 VLQRLEQR----RQQASEREA-----------------PSIEQRLQEVRESIRRAQVSQV 387
Query: 407 KYEAWLAEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQ 466
K A LA +L G + R +P A + + + P +E+++
Sbjct: 388 KGAARLA-----LLQGAGLDVERWLKPAMTQAQDEVEQERRLSEARLSQRDLSPTAEDAE 442
Query: 467 --DTPIYTEFDEDFEEEPTSPIGH----CVA--IYHFEGSSEGTISMAEGEDLSLMEEDK 518
D E E FEE + C A ++ ++ E +++ EGE L ++EE
Sbjct: 443 LSDFEECEETGELFEEPAPQALATRALPCPAHVVFRYQAGREDELTITEGEWLEVIEEGD 502
Query: 519 GDGWTRVRRKEGGEGYVPTSYL 540
D W + R + G G+VP YL
Sbjct: 503 ADEWVKARNQHGEVGFVPERYL 524
>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
Length = 822
Score = 72.8 bits (177), Expect = 8e-13
Identities = 61/288 (21%), Positives = 133/288 (46%), Gaps = 11/288 (3%)
Query: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK 60
M +G++L + E + + W L LL+ KF+ R + ++ YA L++L + + +
Sbjct: 1 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ 60
Query: 61 DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG 120
+ S S+ S++ ++Q+ + + AE+L+ LT ++ +Q +K +
Sbjct: 61 MNYVSNVSK--SWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVH 118
Query: 121 RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQ---AH 177
++ + ++ K + K + R+ K +A+ ++ A + EKAK++ A
Sbjct: 119 QQIEAEM---IKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKAT 175
Query: 178 LRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEA 237
++ HM N+Y L+ Q +Y +P + D LQ M E L + S+
Sbjct: 176 MKLHMLH---NQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQI 232
Query: 238 ELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFE 285
V I + ++++ +DP + + I++H++ A+ ++EF+
Sbjct: 233 TSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFD 280
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 59.3 bits (142), Expect = 9e-09
Identities = 68/321 (21%), Positives = 131/321 (40%), Gaps = 53/321 (16%)
Query: 6 ELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPK-RPAKDDPE 64
+L +Q + LE+ T+ + LL F +++ E+E Y++ L L ++++ K R KD +
Sbjct: 27 QLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQ 86
Query: 65 SKFSQQQS---------FVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEM-KQERK 114
K Q Q+ +E D A ++ N+ +R +++++ S M K+ ++
Sbjct: 87 YKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRF-MQISEDSTRMFKKSKE 145
Query: 115 MHFQEGRRAQQQLENGFKQLEN------SKRKFERDCREAEKAAQTA------------- 155
+ FQ + L + ++ E +EAEK +
Sbjct: 146 IAFQLHEDLMKVLNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQIGRSGDPVFHIRL 205
Query: 156 -ERLDQDINATKADVEKAKQQAHLRSHMAE--ESKNEYAAQLQRFNRDQAHFYFSQMPQI 212
ER + + K + K K+QA + + +++NEY L+ N +Y + +
Sbjct: 206 EERHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNASVFKYYIHDLSDL 265
Query: 213 FDKLQ-----DMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVD---PKND 264
D ++ T L A Y L + EG+ + NAVD P++D
Sbjct: 266 IDCCDLGYHASLNRALRTYLSAEYNLETSRH-----------EGLDIIENAVDNLEPRSD 314
Query: 265 SHVLIELHKSGFARPGDVEFE 285
+E++ + F P EF+
Sbjct: 315 KQRFMEMYPAAFCPPMKFEFQ 335
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 56.6 bits (135), Expect = 6e-08
Identities = 69/326 (21%), Positives = 129/326 (39%), Gaps = 61/326 (18%)
Query: 5 TELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPE 64
T+L +QF+ LE+ ++ L LL +F + + E+E Y++ L L +++ K + E
Sbjct: 26 TQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSK--IRSSRE 83
Query: 65 SKFSQQQSFV-----------QILQEVNDFAGQRELVAENLSVRVCL------------- 100
+F + Q + Q +E D A ++ N+ VR+
Sbjct: 84 HQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSK 143
Query: 101 --------ELTKYSQEMKQERK---MHFQEGRRAQQQLENGFKQLENSKRKFERDCREAE 149
EL K + E+ K M+ E A+ +L+ KQ E ++F + +
Sbjct: 144 EIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEE---KQFNKSGDLSM 200
Query: 150 KAAQTAERLDQDINATKADVEKAKQQAHLRSHMAE--ESKNEYAAQLQRFNRDQAHFYFS 207
+ +R + + K + K K+QA + + +++N+Y L N + +Y
Sbjct: 201 NLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIH 260
Query: 208 QMPQIFDKLQ-----DMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAV--- 259
+ + D + T L A Y L + EG+ V NAV
Sbjct: 261 DVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRH-----------EGLDVIENAVDNL 309
Query: 260 DPKNDSHVLIELHKSGFARPGDVEFE 285
D ++D H ++++ F P EF+
Sbjct: 310 DSRSDKHTVMDMCNQVFCPPLKFEFQ 335
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 56.6 bits (135), Expect = 6e-08
Identities = 69/326 (21%), Positives = 129/326 (39%), Gaps = 61/326 (18%)
Query: 5 TELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPE 64
T+L +QF+ LE+ ++ L LL +F + + E+E Y++ L L +++ K + E
Sbjct: 26 TQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSK--IRSSRE 83
Query: 65 SKFSQQQSFV-----------QILQEVNDFAGQRELVAENLSVRVCL------------- 100
+F + Q + Q +E D A ++ N+ VR+
Sbjct: 84 HQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSK 143
Query: 101 --------ELTKYSQEMKQERK---MHFQEGRRAQQQLENGFKQLENSKRKFERDCREAE 149
EL K + E+ K M+ E A+ +L+ KQ E ++F + +
Sbjct: 144 EIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEE---KQFNKSGDLSM 200
Query: 150 KAAQTAERLDQDINATKADVEKAKQQAHLRSHMAE--ESKNEYAAQLQRFNRDQAHFYFS 207
+ +R + + K + K K+QA + + +++N+Y L N + +Y
Sbjct: 201 NLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIH 260
Query: 208 QMPQIFDKLQ-----DMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAV--- 259
+ + D + T L A Y L + EG+ V NAV
Sbjct: 261 DVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRH-----------EGLDVIENAVDNL 309
Query: 260 DPKNDSHVLIELHKSGFARPGDVEFE 285
D ++D H ++++ F P EF+
Sbjct: 310 DSRSDKHTVMDMCNQVFCPPLKFEFQ 335
>gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens]
Length = 677
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 14/207 (6%)
Query: 340 PEQQRKRLQQQLEERSRELQKEVDQREALK--KMKDVYEKTPQMGDPASLEPQIAETLSN 397
P Q +R Q+L+++ L E +EAL+ K + +Y++ Q+ + LS
Sbjct: 9 PLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSK 68
Query: 398 IERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHA----RPPDPPASAPPDSSSNSASQDT 453
+ V Y E E +L L A R AP + S S+D+
Sbjct: 69 ADE-SAPVANYNQ-RKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDS 126
Query: 454 KESSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSL 513
++S E E ++ E E+ E S +A+ F G ++ +GE L +
Sbjct: 127 EDSGGEEEDAEEEE-----EEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLV 181
Query: 514 MEEDKGDGWTRVRRKEGGEGYVPTSYL 540
+E+ K DGW + +G EG VP +YL
Sbjct: 182 IEK-KPDGWWIAKDAKGNEGLVPRTYL 207
>gi|189491774 nephrocystin 1 isoform 2 [Homo sapiens]
Length = 732
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 14/207 (6%)
Query: 340 PEQQRKRLQQQLEERSRELQKEVDQREALK--KMKDVYEKTPQMGDPASLEPQIAETLSN 397
P Q +R Q+L+++ L E +EAL+ K + +Y++ Q+ + LS
Sbjct: 9 PLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSK 68
Query: 398 IERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHA----RPPDPPASAPPDSSSNSASQDT 453
+ V Y E E +L L A R AP + S S+D+
Sbjct: 69 ADE-SAPVANYNQ-RKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDS 126
Query: 454 KESSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSL 513
++S E E ++ E E+ E S +A+ F G ++ +GE L +
Sbjct: 127 EDSGGEEEDAEEEE-----EEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLV 181
Query: 514 MEEDKGDGWTRVRRKEGGEGYVPTSYL 540
+E+ K DGW + +G EG VP +YL
Sbjct: 182 IEK-KPDGWWIAKDAKGNEGLVPRTYL 207
>gi|46397398 nephrocystin 1 isoform 1 [Homo sapiens]
Length = 733
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 14/207 (6%)
Query: 340 PEQQRKRLQQQLEERSRELQKEVDQREALK--KMKDVYEKTPQMGDPASLEPQIAETLSN 397
P Q +R Q+L+++ L E +EAL+ K + +Y++ Q+ + LS
Sbjct: 9 PLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSK 68
Query: 398 IERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHA----RPPDPPASAPPDSSSNSASQDT 453
+ V Y E E +L L A R AP + S S+D+
Sbjct: 69 ADE-SAPVANYNQ-RKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDS 126
Query: 454 KESSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSL 513
++S E E ++ E E+ E S +A+ F G ++ +GE L +
Sbjct: 127 EDSGGEEEDAEEEE-----EEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLV 181
Query: 514 MEEDKGDGWTRVRRKEGGEGYVPTSYL 540
+E+ K DGW + +G EG VP +YL
Sbjct: 182 IEK-KPDGWWIAKDAKGNEGLVPRTYL 207
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 56.2 bits (134), Expect = 7e-08
Identities = 68/316 (21%), Positives = 124/316 (39%), Gaps = 44/316 (13%)
Query: 1 MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPK--RP 58
M W +L +Q LE + +LL +F++ R EVE Y++ L L +++ + R
Sbjct: 24 MRW--QLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRL 81
Query: 59 AKDDPESKFSQQQSFVQIL-----------QEVNDFAGQRELVAENLSVRVCL------E 101
F ++ S + L Q+ + A E++A L+ R+
Sbjct: 82 GSSREHQSFRKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGR 141
Query: 102 LTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQD 161
L K S++++Q+ + E Q + ++ E REAE+ Q +R +
Sbjct: 142 LVKKSRDLEQQLQDELLEVVSELQTAKKTYQAYHMESVNAEAKLREAER--QEEKRAGRS 199
Query: 162 INATKADVEKA----------------KQQAHLRSHMAE--ESKNEYAAQLQRFNRDQAH 203
+ T A +A K+QA H + +++NEY L N ++
Sbjct: 200 VPTTTAGATEAGPLRKSSLKKGGRLVEKRQAKFMEHKLKCTKARNEYLLSLASVNAAVSN 259
Query: 204 FYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKN 263
+Y + + D + D LG + AE + L ++ A A+DP
Sbjct: 260 YY---LHDVLDLMDCCDTGFHLALGQVLRSYTAAESRTQASQVQGLGSLEEAVEALDPPG 316
Query: 264 DSHVLIELHKSGFARP 279
D ++E+H + F P
Sbjct: 317 DKAKVLEVHATVFCPP 332
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 55.1 bits (131), Expect = 2e-07
Identities = 55/274 (20%), Positives = 118/274 (43%), Gaps = 19/274 (6%)
Query: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
FE+L + G + +F++ER ++E+ YAK L L + L + + S
Sbjct: 156 FELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLAS-------QEEGSLG 208
Query: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
+++ Q+ + + D A + L V L + + K++ K ++QL +
Sbjct: 209 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASR 268
Query: 131 FKQLENSKRKFERDCREAEKAAQTAE-RLDQDINATKADVEKAKQQAHLRSHMAEESKNE 189
+ +E +++ R+ E Q E +L N T+ D++KA+++ + ++ ++
Sbjct: 269 YASVEKARKALTERQRDLEMKTQQLEIKLS---NKTEEDIKKARRK-------STQAGDD 318
Query: 190 YAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCL 249
+ +N+ Q+ +F +M +L+ ++ R + ++ E +
Sbjct: 319 LMRCVDLYNQAQSK-WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 377
Query: 250 EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVE 283
E + VDP D + + HK+G RP D+E
Sbjct: 378 EPVDQLLRKVDPAKDRELWVREHKTGNIRPVDME 411
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 55.1 bits (131), Expect = 2e-07
Identities = 55/274 (20%), Positives = 118/274 (43%), Gaps = 19/274 (6%)
Query: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
FE+L + G + +F++ER ++E+ YAK L L + L + + S
Sbjct: 220 FELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLAS-------QEEGSLG 272
Query: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
+++ Q+ + + D A + L V L + + K++ K ++QL +
Sbjct: 273 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASR 332
Query: 131 FKQLENSKRKFERDCREAEKAAQTAE-RLDQDINATKADVEKAKQQAHLRSHMAEESKNE 189
+ +E +++ R+ E Q E +L N T+ D++KA+++ + ++ ++
Sbjct: 333 YASVEKARKALTERQRDLEMKTQQLEIKLS---NKTEEDIKKARRK-------STQAGDD 382
Query: 190 YAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCL 249
+ +N+ Q+ +F +M +L+ ++ R + ++ E +
Sbjct: 383 LMRCVDLYNQAQSK-WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 441
Query: 250 EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVE 283
E + VDP D + + HK+G RP D+E
Sbjct: 442 EPVDQLLRKVDPAKDRELWVREHKTGNIRPVDME 475
Score = 33.9 bits (76), Expect = 0.39
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 489 CVAIYHFEGSSEGT-ISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYLRV 542
C +Y F G G + A GE ++L++ G GW +++G G+ P SY+++
Sbjct: 6 CRTLYPFSGERHGQGLRFAAGELITLLQVPDG-GWWEGEKEDGLRGWFPASYVQL 59
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 55.1 bits (131), Expect = 2e-07
Identities = 55/274 (20%), Positives = 118/274 (43%), Gaps = 19/274 (6%)
Query: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
FE+L + G + +F++ER ++E+ YAK L L + L + + S
Sbjct: 160 FELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLAS-------QEEGSLG 212
Query: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
+++ Q+ + + D A + L V L + + K++ K ++QL +
Sbjct: 213 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASR 272
Query: 131 FKQLENSKRKFERDCREAEKAAQTAE-RLDQDINATKADVEKAKQQAHLRSHMAEESKNE 189
+ +E +++ R+ E Q E +L N T+ D++KA+++ + ++ ++
Sbjct: 273 YASVEKARKALTERQRDLEMKTQQLEIKLS---NKTEEDIKKARRK-------STQAGDD 322
Query: 190 YAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCL 249
+ +N+ Q+ +F +M +L+ ++ R + ++ E +
Sbjct: 323 LMRCVDLYNQAQSK-WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 381
Query: 250 EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVE 283
E + VDP D + + HK+G RP D+E
Sbjct: 382 EPVDQLLRKVDPAKDRELWVREHKTGNIRPVDME 415
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 55.1 bits (131), Expect = 2e-07
Identities = 55/274 (20%), Positives = 118/274 (43%), Gaps = 19/274 (6%)
Query: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
FE+L + G + +F++ER ++E+ YAK L L + L + + S
Sbjct: 80 FELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLAS-------QEEGSLG 132
Query: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
+++ Q+ + + D A + L V L + + K++ K ++QL +
Sbjct: 133 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASR 192
Query: 131 FKQLENSKRKFERDCREAEKAAQTAE-RLDQDINATKADVEKAKQQAHLRSHMAEESKNE 189
+ +E +++ R+ E Q E +L N T+ D++KA+++ + ++ ++
Sbjct: 193 YASVEKARKALTERQRDLEMKTQQLEIKLS---NKTEEDIKKARRK-------STQAGDD 242
Query: 190 YAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCL 249
+ +N+ Q+ +F +M +L+ ++ R + ++ E +
Sbjct: 243 LMRCVDLYNQAQSK-WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 301
Query: 250 EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVE 283
E + VDP D + + HK+G RP D+E
Sbjct: 302 EPVDQLLRKVDPAKDRELWVREHKTGNIRPVDME 335
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/194 (22%), Positives = 90/194 (46%), Gaps = 10/194 (5%)
Query: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
+EVL + G + + +++R + E+ Y K+L + +K A E S +
Sbjct: 22 YEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARK------AGGQTEIN-SLR 74
Query: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
SF + Q++ + +A L + L ++ + K++RK + R Q+ +
Sbjct: 75 ASFDSLKQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSL 133
Query: 131 FKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEY 190
+K+ SK+ +E+ CR+A+ A Q ER+ N + VEK++ +A A E++ Y
Sbjct: 134 YKKAMESKKTYEQKCRDADDAEQAFERI--SANGHQKQVEKSQNKARQCKDSATEAERVY 191
Query: 191 AAQLQRFNRDQAHF 204
+ + + +A +
Sbjct: 192 RQSIAQLEKVRAEW 205
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 442 PDSSSNSASQDTKESSEEPPSEESQDTPIYTEFD-EDFEEEPTSPIGHCVAIYHFEGSSE 500
P ++S +AS + E+ P ++ +YT ++ + P SP A+Y + +
Sbjct: 319 PKTTSLAASAASTETLTPTPE---RNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNP 375
Query: 501 GTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYL 540
+ ++ G+ L ++ E + DGW V R G G+VP SYL
Sbjct: 376 DELDLSAGDILEVILEGE-DGWWTVER-NGQRGFVPGSYL 413
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 52.4 bits (124), Expect = 1e-06
Identities = 65/292 (22%), Positives = 120/292 (41%), Gaps = 38/292 (13%)
Query: 3 WGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDD 62
WG E F+VL + + G FV+ER +E+AY++ + L K
Sbjct: 11 WG-EKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKS---------- 59
Query: 63 PESKFSQQQSFV---QILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQE 119
S +SQ +F + + + L + E+ KY +E + K +E
Sbjct: 60 -ASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEE 118
Query: 120 ---GRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQA 176
A Q +++ + L+ SK + C E E+ + AT+ ++EKA +
Sbjct: 119 VAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKE--------GATQREIEKAAVK- 169
Query: 177 HLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSE 236
++++ + Y ++++ +A F +M + K QD++E + G LS
Sbjct: 170 ------SKKATDTYKLYVEKYALAKADFE-QKMTETAQKFQDIEETHLIHIKEIIGSLSN 222
Query: 237 AELEVVPIIAKCLEGMKVAANAVDPKNDSHV--LIELHKSGFARPGDVEFED 286
A E+ I + E + N + +S + E +G RPG +EFE+
Sbjct: 223 AIKEIHLQIGQVHE--EFINNMANTTVESLIQKFAESKGTGKERPGLIEFEE 272
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 52.4 bits (124), Expect = 1e-06
Identities = 93/487 (19%), Positives = 211/487 (43%), Gaps = 39/487 (8%)
Query: 14 LERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSF 73
L++ Q DL R + K+ E+E+ R ++K K A + + K ++Q+
Sbjct: 753 LQQQRQLNTDLELRATELSKQ-LEMEKEIVSSTRLDLQK---KSEALESIKQKLTKQEEE 808
Query: 74 VQIL-QEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFK 132
QIL Q+ + + ++ E L+ R+ +T+ Q++K E++ E + +L
Sbjct: 809 KQILKQDFETLSQETKIQHEELNNRIQTTVTEL-QKVKMEKEALMTELSTVKDKLSKVSD 867
Query: 133 QLENSKRKFERDCREAEKAAQTAERLDQDI-NATKADVEKA-KQQAHLRSHMAEESKNEY 190
L+NSK +FE++ ++ + A E+ +++ + + +E K+Q L+ + +E + +
Sbjct: 868 SLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASH 927
Query: 191 AAQLQ-----------RFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAEL 239
+L+ + Q Q+ ++L+ E++ ++ A G L A L
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987
Query: 240 EVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSS 299
+ + K + + AA + + + I + ++ + + + F+ S+
Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEK---ISVLQNNYEKSQET-FKQLQSDFYGRESE-L 1042
Query: 300 LGTPSDGRPELRGPGRSR----TKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERS 355
L T D + ++ + R G +NK + + EQ + +QQL+ER
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERC 1102
Query: 356 RELQKEVDQREALKKMKDVYEKTPQMGDPASL----EPQIAETLSNIERLKLEVQKYEAW 411
+ LQ ++ + ++LK+ + V EK+ ++ + + E +I + ++ KLE K
Sbjct: 1103 KALQ-DIQKEKSLKEKELVNEKS-KLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 412 LAEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEE--SQDTP 469
L +A+ ++ + L + A+ + + +D + EE +E ++
Sbjct: 1161 LKDAKQLLIQQK---LELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAK 1217
Query: 470 IYTEFDE 476
+++E E
Sbjct: 1218 LHSEIKE 1224
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.0 bits (123), Expect = 1e-06
Identities = 85/423 (20%), Positives = 175/423 (41%), Gaps = 48/423 (11%)
Query: 39 EQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQIL--QEVNDFAGQRELVAENLSV 96
E+ ++L+ ++ L +R +++ E + Q++ Q L +E + Q+ L +E
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVE-RLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 97 RVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAE 156
R +L + QE +++R +E R +Q+L+ ++ E +R+ E E E+A + +
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLK---REHEEERREQELAEEEQEQARERIK 698
Query: 157 --------RLDQDINATKADV--EKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYF 206
+L+ + +A ++ V KQ+ R EE + ++LQ ++AH
Sbjct: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
Query: 207 SQMPQIFD-----KLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDP 261
+ Q D + ++ ER RL A L + E ++ + E + +
Sbjct: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL-----RAEERQQREQRFLPE 813
Query: 262 KNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKR- 320
+ + + + R +++F + + + R L DG E + RS+ +R
Sbjct: 814 EEEKE---QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
Query: 321 -----WPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVY 375
W ++ K ++ ++Q ++ QQ L+E ELQ+E ++ ++ + Y
Sbjct: 871 DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 930
Query: 376 EKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAW------LAEAESRVLSNRGDSLSR 429
+ Q+ Q E L ER K Q+ E L + E ++L + R
Sbjct: 931 REEEQL-------QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 430 HAR 432
R
Sbjct: 984 QER 986
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/232 (18%), Positives = 101/232 (43%), Gaps = 18/232 (7%)
Query: 9 DQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFS 68
++ ++L+ + L +R KF++E EQ +Q R +K+ + +PE KF
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEE----EQQLRRQERD--RKFREQELRSQEPERKFL 1518
Query: 69 QQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLE 128
+++ Q+++ QR+ + E +R + Q+ +Q+R F+E + +Q+ E
Sbjct: 1519 EEE------QQLHRQQRQRKFLQEEQQLR----RQERGQQRRQDRDRKFREEEQLRQERE 1568
Query: 129 NGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKN 188
+ RKF + ++ + Q + ++ + + + ++ +Q R +E
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
Query: 189 EYAAQLQRFNRDQAHFYFSQMPQI--FDKLQDMDERRATRLGAGYGLLSEAE 238
+ + Q +++ + + PQ+ ++ Q + R + LL E E
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Score = 39.7 bits (91), Expect = 0.007
Identities = 84/424 (19%), Positives = 156/424 (36%), Gaps = 54/424 (12%)
Query: 35 RTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ---QSFVQILQEVNDFAGQRELVA 91
R E + +QLR ++ L + ++ E K Q+ Q + +E D+ + E
Sbjct: 408 RREQQLRREQQLRR--EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 92 ENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQ--LENGFKQLENSKRKFERDCREAE 149
+ R +L + +E ++ER + +E R +QQ E ++ + +R+ +E E
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 150 KAAQTAERLDQDI---------NATKADVEKAKQQAHLRSHMAEES--------KNEYAA 192
+ Q R +Q + K + EK +Q + E K E
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 193 QLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGM 252
+ QR R+Q ++ + + + +ERR RL E E E + K E
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR-----EEPEEERRQQLLKSEEQE 640
Query: 253 KVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDS--SLGTPSDGRPEL 310
+ + + L + + E E Q + R + + + +
Sbjct: 641 ERRQQQLRREQQERREQRLKR-------EEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 311 RGPGRSRTKRWPFGKKNKTVVTEDFSHLPP----------EQQRKR------LQQQLEER 354
R +SR +W + +++ + + P EQ+ KR LQ Q EER
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
Query: 355 SRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAE 414
+ Q+E +QR EK+ + S P + E R + Q+ + +L E
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 415 AESR 418
E +
Sbjct: 814 EEEK 817
Score = 39.7 bits (91), Expect = 0.007
Identities = 102/497 (20%), Positives = 193/497 (38%), Gaps = 47/497 (9%)
Query: 16 RHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQ 75
RH + G L+ + R E E+ + K+ + L + ++ + D + KF +++ +
Sbjct: 1368 RHQEQGRKFLEEEQRL--RRQERERKFLKEEQQL-RCQEREQQLRQDRDRKFREEEQQLS 1424
Query: 76 ILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQE-----GRRAQQQL--- 127
+ F + + V R LE Q+++QER F+E R +QQL
Sbjct: 1425 RQERDRKFREEEQQVRRQERERKFLE---EEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 128 --ENGFKQLENSKRKFERD--CREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMA 183
+ F + E R+ ERD RE E +Q ER + + ++ +Q R +
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE------EEQQLHRQQRQRKFLQ 1535
Query: 184 EES--KNEYAAQLQRFNRDQAHFYFSQMPQIFD--KLQDMDERRATRLGAGYGLLSEAEL 239
EE + + Q +R +RD+ Q+ Q + +L + R RL E E
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 240 EVVPIIAKC--LEGMKVAANAVDPK--NDSHVLIELHKSGFAR-PGDVEFEDFSQPMNRA 294
+ + + EG + D K D +L E + R D +F + + R
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Query: 295 PSDSSLGTPSDGR----PELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQ 350
+ L D + +L G + R ++++ E+ E++RK LQ++
Sbjct: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ--ERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 351 LEERSRELQKEVDQREALKKMKDV-----YEKTPQMGDPASLEPQIAETLSNIERLKLEV 405
+ R +EL+++ + E L++ + E+ ++ + L P+ E + +
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
Query: 406 QKYEAWLAEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSE-E 464
++ E E E + L R R R + + +D K EE + E
Sbjct: 1774 REEEQLRQEREEQQL--RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 465 SQDTPIYTEFDEDFEEE 481
Q+ + E D + E
Sbjct: 1832 EQEQRLRQERDRQYRAE 1848
Score = 38.5 bits (88), Expect = 0.016
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Query: 86 QRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDC 145
QREL E +R LE QE+++ER+ Q+ +R +++ + KQ E + + E
Sbjct: 268 QRELQEEEEQLRK-LE----RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 146 REAEKAAQTAERLDQDI---------NATKADVEKAKQQAHLRSHMAEESKNEYAAQLQR 196
+ E+ Q ER +Q + + + E+ +++ LR EE + + + Q+
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 197 FNRDQ 201
R+Q
Sbjct: 383 LRREQ 387
Score = 33.5 bits (75), Expect = 0.51
Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 10/145 (6%)
Query: 92 ENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKA 151
E L R LEL + +E KQ+++ Q+ R Q++ E +++ E RK E +E E
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQD-RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ 266
Query: 152 AQTA--------ERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAH 203
Q +L++ + E+ +QQ R + E + Q R+Q
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 204 FYFSQMPQIFDKL-QDMDERRATRL 227
Q + +L ++ +ERR +L
Sbjct: 327 RREQQEERREQQLRREQEERREQQL 351
Score = 32.3 bits (72), Expect = 1.1
Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 8/94 (8%)
Query: 110 KQERKMHFQEGRRAQQQLENGFKQLENSKRKFERD--CREAEKAAQTAERLDQDINATKA 167
+QER+ +++ ++ QQ+ E + +R+ ER+ RE E+ Q E+L +
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL------LRE 1006
Query: 168 DVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQ 201
+ EK ++Q R + ++ + QL R R++
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Score = 31.2 bits (69), Expect = 2.5
Identities = 30/169 (17%), Positives = 67/169 (39%), Gaps = 5/169 (2%)
Query: 33 KERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAE 92
+ER E EQ + R + + ++ E + QQ+ +E + +++L E
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER-----REQQEERREQQLRRE 342
Query: 93 NLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAA 152
R + +E ++++ QE R +QQL + + + E+ R ++
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 153 QTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQ 201
+ + + + + + +Q + E K+E + QR R+Q
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 110 KQERKMHFQEGRRAQQQLENGFKQLENSKRK--FERDCREAEKAAQTAERLDQDINATKA 167
+QER+ ++E QQ+ E ++ +R+ +ER R+ ++ Q E+L +
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL------LRE 1036
Query: 168 DVEKAKQQAHLRSHMAEESKNEYAAQL 194
+ EK + Q R + EE + QL
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQL 1063
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 48.5 bits (114), Expect = 2e-05
Identities = 65/279 (23%), Positives = 102/279 (36%), Gaps = 31/279 (11%)
Query: 281 DVEFEDFSQPMNRAPSDSSLGTPSDGRP------ELRGPGRSRTKRWPFGKKNKTVVTED 334
+ E +DF + S ++ P + RP E R G T R P G+ + + ED
Sbjct: 549 ETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVR-PRGRSMQALAEED 607
Query: 335 FSHLPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAET 394
HLPP+ +L Q + RS Q + + + DP + Q+
Sbjct: 608 LQHLPPQPLPPQLSQG-DGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSV 666
Query: 395 LSNIE--------RLKLEVQKYEAWLAEAESRV-LSNR----GDSLSRHARPPDPPASAP 441
E L L Q ++ L++ R L NR G S P P A
Sbjct: 667 APPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQ 726
Query: 442 PDSSSNSASQDTKE-SSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHF----- 495
P ++ ++ +E EE EE ++ E +E+ EEE VA+
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRS 786
Query: 496 ----EGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEG 530
EGS T EG +L+ +D+ + R +G
Sbjct: 787 GSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADG 825
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 48.5 bits (114), Expect = 2e-05
Identities = 106/489 (21%), Positives = 183/489 (37%), Gaps = 37/489 (7%)
Query: 12 EVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQ 71
E++ + ++ + +R TE+E+ + L+K + D +Q++
Sbjct: 257 EIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKE 316
Query: 72 SFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGF 131
+ + + +R L A+ + V K E+ + MH Q + +Q E
Sbjct: 317 DMEERITTLE----KRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQE--- 369
Query: 132 KQLENSKRKFERDCREAEKAAQTAERLDQDINA-TKADVEKAKQQAHLRSHMA--EESKN 188
+LE +++K ++ R+AE + L Q + A +KA+ + LR A EE
Sbjct: 370 -RLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQ 428
Query: 189 EYAAQLQRFNRDQAHFYFSQMPQIFDKL-QDMDERRATRLGAGYGLLSEAE--LEVVPII 245
E QR ++ H ++ DKL + +ER L L + L V
Sbjct: 429 ELQRARQREKMNEEHN--KRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESA 486
Query: 246 AKCLEGMK-------VAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDS 298
K LE + + A+ + D H+ + RP DF PM +DS
Sbjct: 487 KKQLEETQHDKDQLVLNIEALRAELD-HMRLRGASLHHGRPHLGSVPDFRFPMADGHTDS 545
Query: 299 SLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSREL 358
+ RP+ GR R K +T+ +D+ + Q E + ++
Sbjct: 546 YSTSAVLRRPQ---KGRLAALR-DEPSKVQTLNEQDWERAQQASVLANVAQAFESDA-DV 600
Query: 359 QKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIER----LKLEVQKYEAWLAE 414
D R+ L D+ + Q D +L + E L I + ++ E + E E
Sbjct: 601 SDGEDDRDTLLSSVDLLSPSGQ-ADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEE 659
Query: 415 AESRVLSNRGDSLSRH---ARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIY 471
ESRV S D+L R + P PAS+ SS + + T P+ E +
Sbjct: 660 IESRVGSGSLDNLGRFRSMSSIPPYPASSLASSSPPGSGRSTPRRIPHSPAREVDRLGVM 719
Query: 472 TEFDEDFEE 480
T EE
Sbjct: 720 TLLPPSREE 728
Score = 33.1 bits (74), Expect = 0.67
Identities = 27/154 (17%), Positives = 64/154 (41%)
Query: 10 QFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQ 69
Q E R Q L+L ++ ++ + E +L V + E + Q
Sbjct: 359 QTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQ 418
Query: 70 QQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLEN 129
++ ++ + A QRE + E + R+ + K E + ++H +E A + +
Sbjct: 419 MEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNS 478
Query: 130 GFKQLENSKRKFERDCREAEKAAQTAERLDQDIN 163
+++E++K++ E + ++ E L +++
Sbjct: 479 LLREVESAKKQLEETQHDKDQLVLNIEALRAELD 512
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 48.5 bits (114), Expect = 2e-05
Identities = 106/489 (21%), Positives = 183/489 (37%), Gaps = 37/489 (7%)
Query: 12 EVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQ 71
E++ + ++ + +R TE+E+ + L+K + D +Q++
Sbjct: 257 EIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKE 316
Query: 72 SFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGF 131
+ + + +R L A+ + V K E+ + MH Q + +Q E
Sbjct: 317 DMEERITTLE----KRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQE--- 369
Query: 132 KQLENSKRKFERDCREAEKAAQTAERLDQDINA-TKADVEKAKQQAHLRSHMA--EESKN 188
+LE +++K ++ R+AE + L Q + A +KA+ + LR A EE
Sbjct: 370 -RLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQ 428
Query: 189 EYAAQLQRFNRDQAHFYFSQMPQIFDKL-QDMDERRATRLGAGYGLLSEAE--LEVVPII 245
E QR ++ H ++ DKL + +ER L L + L V
Sbjct: 429 ELQRARQREKMNEEHN--KRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESA 486
Query: 246 AKCLEGMK-------VAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDS 298
K LE + + A+ + D H+ + RP DF PM +DS
Sbjct: 487 KKQLEETQHDKDQLVLNIEALRAELD-HMRLRGASLHHGRPHLGSVPDFRFPMADGHTDS 545
Query: 299 SLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSREL 358
+ RP+ GR R K +T+ +D+ + Q E + ++
Sbjct: 546 YSTSAVLRRPQ---KGRLAALR-DEPSKVQTLNEQDWERAQQASVLANVAQAFESDA-DV 600
Query: 359 QKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIER----LKLEVQKYEAWLAE 414
D R+ L D+ + Q D +L + E L I + ++ E + E E
Sbjct: 601 SDGEDDRDTLLSSVDLLSPSGQ-ADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEE 659
Query: 415 AESRVLSNRGDSLSRH---ARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIY 471
ESRV S D+L R + P PAS+ SS + + T P+ E +
Sbjct: 660 IESRVGSGSLDNLGRFRSMSSIPPYPASSLASSSPPGSGRSTPRRIPHSPAREVDRLGVM 719
Query: 472 TEFDEDFEE 480
T EE
Sbjct: 720 TLLPPSREE 728
Score = 33.1 bits (74), Expect = 0.67
Identities = 27/154 (17%), Positives = 64/154 (41%)
Query: 10 QFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQ 69
Q E R Q L+L ++ ++ + E +L V + E + Q
Sbjct: 359 QTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQ 418
Query: 70 QQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLEN 129
++ ++ + A QRE + E + R+ + K E + ++H +E A + +
Sbjct: 419 MEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNS 478
Query: 130 GFKQLENSKRKFERDCREAEKAAQTAERLDQDIN 163
+++E++K++ E + ++ E L +++
Sbjct: 479 LLREVESAKKQLEETQHDKDQLVLNIEALRAELD 512
>gi|24308229 protein kinase C and casein kinase substrate in neurons
1 [Homo sapiens]
Length = 444
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/215 (21%), Positives = 94/215 (43%), Gaps = 20/215 (9%)
Query: 21 GLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEV 80
G L + + V+ER ++E+AY +QL K++ R + S ++++ I+ E
Sbjct: 35 GHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRW---RQLIEKGPQYGSLERAWGAIMTEA 91
Query: 81 NDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGF--------- 131
+ + + V NL + +L K K G + ++ E+GF
Sbjct: 92 DKVSELHQEVKNNL---LNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAK 148
Query: 132 --KQLENSKRKFERDCREAEKAAQTAERLDQ-DINATKADVEKAKQQAHLRSHMAEESKN 188
K+LE +K+ + C+E EK A T E + + + T +K + + ++++
Sbjct: 149 KMKELEAAKKAYHLACKE-EKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQE 207
Query: 189 EYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERR 223
+Y L+ + Y M Q+F++ Q +E+R
Sbjct: 208 KYEKVLEDVGKTTPQ-YMENMEQVFEQCQQFEEKR 241
Score = 38.1 bits (87), Expect = 0.021
Identities = 63/286 (22%), Positives = 104/286 (36%), Gaps = 79/286 (27%)
Query: 325 KKNKTVVTEDFSH-----LPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTP 379
K+ K +T + + + PEQQ+K LQ ++++ +++QK ++ E K ++DV + TP
Sbjct: 165 KEEKLAMTREMNSKTEQSVTPEQQKK-LQDKVDKCKQDVQKTQEKYE--KVLEDVGKTTP 221
Query: 380 QMGDPASLEPQIAETLSNIERLKL----EVQ---KYEAWLAEAESRV-------LSNRGD 425
Q + Q+ E E +L EV K LAE S + + RG
Sbjct: 222 QYMENME---QVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGA 278
Query: 426 SLSRHAR------PPDPPASAPPDSSSNSASQDTKESSEEPP------------------ 461
R P P + P N T E+ P
Sbjct: 279 DAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTTKKEKQPKKAEGVALTNATGAVEST 338
Query: 462 ---------SEESQDTPIYTEFDEDFEEEPTSPIG------------------HCVAIYH 494
S + P TE+ +D E +P G A+Y
Sbjct: 339 SQAGDRGSVSSYDRGQPYATEWSDD---ESGNPFGGSETNGGANPFEDDSKGVRVRALYD 395
Query: 495 FEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYL 540
++G + +S G++L+ + E+ GW R R G G P +Y+
Sbjct: 396 YDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYV 441
>gi|189491778 nephrocystin 1 isoform 4 [Homo sapiens]
Length = 614
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
Query: 440 APPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEGSS 499
AP + S S+D+++S E E ++ E E+ E S +A+ F
Sbjct: 51 APTEEEEESESEDSEDSGGEEEDAEEEE-----EEKEENESHKWSTGEEYIAVGDFTAQQ 105
Query: 500 EGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYL 540
G ++ +GE L ++E+ K DGW + +G EG VP +YL
Sbjct: 106 VGDLTFKKGEILLVIEK-KPDGWWIAKDAKGNEGLVPRTYL 145
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 47.4 bits (111), Expect = 3e-05
Identities = 108/484 (22%), Positives = 202/484 (41%), Gaps = 72/484 (14%)
Query: 36 TEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENL- 94
TE E A K+ K L K AK + ++ V ++QE ND Q + +ENL
Sbjct: 846 TEKEMATMKEEFQKTKDELAKSEAK-----RKELEEKLVTLVQEKNDLQLQVQAESENLL 900
Query: 95 -SVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQ 153
+ C +L K +++ + K + RA+ + E +L KRK E +C E +K
Sbjct: 901 DAEERCDQLIKAKFQLEAKIK---EVTERAEDEEEIN-AELTAKKRKLEDECSELKKDI- 955
Query: 154 TAERLDQDINATKADVEKAKQQAHLR-SHMAEE--SKNEYAAQLQRFNR--DQAHFY-FS 207
D+ T A VEK K + ++ EE +E A+L R + +AH
Sbjct: 956 ------DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD 1009
Query: 208 QMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPII-----AKCLEG-MKVAANAV-D 260
+ DK+ +++ ++ L S E E + + LEG +K+A ++ D
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069
Query: 261 PKNDSHVLIE-LHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTK 319
+ND L E L K F ++ Q ++ + +LG L+ + +
Sbjct: 1070 LENDKQQLDERLKKKDF---------EYCQLQSKVEDEQTLG--------LQFQKKIKEL 1112
Query: 320 RWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQK---------EVDQR---EA 367
+ + + + E + E+QR ++LEE S L++ E++++ E
Sbjct: 1113 QARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF 1172
Query: 368 LKKMKDVYEKTPQ--------MGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRV 419
LK +D+ E T Q A ++ E + N++R+K +++K ++ + E
Sbjct: 1173 LKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEF-KLEIDD 1231
Query: 420 LSNRGDSLSRHARPPDPPASAPPD--SSSNSASQDTKESSEEPPSEESQDTPIYTEFDED 477
LS+ +S+S+ + D S + +++ + S E +++S+ E
Sbjct: 1232 LSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQ 1291
Query: 478 FEEE 481
EE+
Sbjct: 1292 LEEK 1295
Score = 32.7 bits (73), Expect = 0.87
Identities = 71/368 (19%), Positives = 144/368 (39%), Gaps = 56/368 (15%)
Query: 21 GLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEV 80
GLD + K +E+ +++A+ + L L A++D + ++ +S ++ Q+V
Sbjct: 985 GLD--ETIAKLTREKKALQEAHQQALDDL--------QAEEDKVNSLNKTKSKLE--QQV 1032
Query: 81 NDFAGQRELVAENLSVRVCLELTKYSQE----MKQERKMHFQEGRRAQQQLENGFKQLEN 136
D E + +RV LE K E + QE + + + QQL+ K+ +
Sbjct: 1033 EDLESSLE---QEKKLRVDLERNKRKLEGDLKLAQESILDLENDK---QQLDERLKKKDF 1086
Query: 137 SKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQR 196
+ + + + ++ +++ A ++E+ + E+ +++YA +L+
Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146
Query: 197 FNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIA----KCLEGM 252
+ QI +++++R L EA L+ ++A K + +
Sbjct: 1147 LSERLEEAGGVTSTQI-----ELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSV 1201
Query: 253 KVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPM-----NRAPSDSSLGTPSDGR 307
+D +E KS F +E +D S M ++A + T D
Sbjct: 1202 AELGEQIDNLQRVKQKLEKEKSEFK----LEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
Query: 308 PELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQKEVDQREA 367
E RG KN+ + S L Q+ RLQ + E SR+L+++
Sbjct: 1258 SEARG-------------KNEEI-QRSLSELTT--QKSRLQTEAGELSRQLEEKESIVSQ 1301
Query: 368 LKKMKDVY 375
L + K +
Sbjct: 1302 LSRSKQAF 1309
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/156 (21%), Positives = 64/156 (41%), Gaps = 11/156 (7%)
Query: 25 LDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEV--ND 82
L+ V + + +QA+ +Q L ++ + AK+ + +L+E +
Sbjct: 1292 LEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEE 1351
Query: 83 FAGQREL--VAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRK 140
G+ EL + V TKY + Q + + ++ Q+L++ +Q+E K
Sbjct: 1352 QEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAK 1411
Query: 141 FERDCREAEKAAQTAERLDQDINATKADVEKAKQQA 176
C EK T +RL ++ DVE+A A
Sbjct: 1412 ----CASLEK---TKQRLQGEVEDLMVDVERANSLA 1440
Score = 30.8 bits (68), Expect = 3.3
Identities = 40/203 (19%), Positives = 84/203 (41%), Gaps = 18/203 (8%)
Query: 10 QFEVLERHTQWGLDLLDRYV---KFVKERTEVEQA-YAKQLRSLVKKYLPKRPAKDDP-E 64
QF+ + Q ++ L+ + + + +TE +++ YA++L L ++ E
Sbjct: 1104 QFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIE 1163
Query: 65 SKFSQQQSFVQILQEVNDFAGQRELVAENL------SVRVCLELTKYSQEMKQERKMHFQ 118
++ F+++ +++ + Q E + L SV E Q +KQ+ +
Sbjct: 1164 LNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1223
Query: 119 EGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHL 178
E + L + + + SK E+ CR E A +++I + + E Q++ L
Sbjct: 1224 EFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS--ELTTQKSRL 1281
Query: 179 RSHMAE-----ESKNEYAAQLQR 196
++ E E K +QL R
Sbjct: 1282 QTEAGELSRQLEEKESIVSQLSR 1304
Score = 29.6 bits (65), Expect = 7.4
Identities = 32/163 (19%), Positives = 66/163 (40%), Gaps = 29/163 (17%)
Query: 57 RPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMH 116
R A++ + + + L++ D + E + +NL V + + ++
Sbjct: 1750 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV----KDLQHRLDEAEQLA 1805
Query: 117 FQEGRRAQQQLENGFKQLE--------------NSKRKFERDCRE----AEKAAQTAERL 158
+ G++ Q+LE ++LE RK+ER +E +E+ + RL
Sbjct: 1806 LKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRL 1865
Query: 159 DQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQ 201
++ + V+ K+QA EE+ + A L +F + Q
Sbjct: 1866 QDLVDKLQVKVKSYKRQA-------EEADEQANAHLTKFRKAQ 1901
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 47.4 bits (111), Expect = 3e-05
Identities = 92/426 (21%), Positives = 185/426 (43%), Gaps = 62/426 (14%)
Query: 36 TEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENLS 95
TE E A K+ K L K AK + ++ V +L+E ND Q + A++L+
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAK-----RKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 96 --VRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQ 153
C +L K +++ + K + RA+++ E +L KRK E +C E +K
Sbjct: 903 DAEERCEQLIKNKIQLEAKIK---EVTERAEEEEEIN-AELTAKKRKLEDECSELKKDID 958
Query: 154 TAE----RLDQDINATKADVEK-AKQQAHLRSHMAEESKNEYAAQ---LQRFNRDQAHFY 205
E +++++ +AT+ V+ ++ A L +A+ SK + A Q Q + QA
Sbjct: 959 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE-- 1016
Query: 206 FSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANA-VDPKND 264
I K + E++ L + +++ K +K+A + +D +ND
Sbjct: 1017 -EDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEND 1075
Query: 265 SHVLIE-LHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKRWPF 323
L E L K F + S +++ + ++ E++ + + +
Sbjct: 1076 KQQLDEKLEKKEF---------EISNLISKIEDEQAV--------EIQLQKKIKELQARI 1118
Query: 324 GKKNKTVVTEDFSHLPPEQQRKRLQQQLEERSRELQK----EVDQREALKKMKDVYEKTP 379
+ + + E S E+QR L ++LEE S L++ Q E KK + ++K
Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178
Query: 380 QMGDPASLE----------------PQIAETLSNIERLKLEVQKYEAWLAEAESRVLSNR 423
+ + A+L+ ++ E + N++R+K +++K ++ L + E+ LS+
Sbjct: 1179 RDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSEL-KMETDDLSSN 1237
Query: 424 GDSLSR 429
+++S+
Sbjct: 1238 AEAISK 1243
Score = 41.6 bits (96), Expect = 0.002
Identities = 85/428 (19%), Positives = 175/428 (40%), Gaps = 57/428 (13%)
Query: 27 RYVKFVKERTEVEQA---YAKQLRSLVKKYLPKRPAKDDP-------ESKFSQQQSFVQI 76
R +F K R ++E+A + + +L KK+ + + K +++S ++
Sbjct: 1170 REAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKS--EL 1227
Query: 77 LQEVNDFAGQRELVAE---NLSVRVCLELTKYSQEMK-----QERKMHFQEGRRAQQQLE 128
E +D + E +++ NL ++C L E+K Q+R ++ +RA+ Q E
Sbjct: 1228 KMETDDLSSNAEAISKAKGNLE-KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTE 1286
Query: 129 NG--FKQLENSKRKFERDCREAEKAAQTAE----RLDQDINATKADVEKAKQQAH----L 178
G +QL+ + R + + Q E +L+++ A A + H L
Sbjct: 1287 AGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLL 1346
Query: 179 RSHMAEES--KNEYAAQLQRFNRDQAHF---YFSQMPQIFDKLQDMDERRATRLGAGYGL 233
R EE K E L + N + A + Y + Q ++L++ ++ A RL
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL------ 1400
Query: 234 LSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPG-DVEFEDFSQPMN 292
EAE V + AKC K + D +++++ +S A D + +F + ++
Sbjct: 1401 -QEAEEHVEAVNAKCASLEKTKQRLQNEVED--LMLDVERSNAACAALDKKQRNFDKVLS 1457
Query: 293 RAPSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPP-EQQRKRLQQQL 351
+ + EL + K K V E L ++ K LQQ++
Sbjct: 1458 EWKQKYE-----ETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512
Query: 352 EERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAW 411
+ + ++ + Q L+K+K E+ + ++ + E +++E + ++ + +
Sbjct: 1513 SDLTEQIAEGGKQIHELEKIKKQVEQ-----EKCEIQAALEEAEASLEHEEGKILRIQLE 1567
Query: 412 LAEAESRV 419
L + +S V
Sbjct: 1568 LNQVKSEV 1575
Score = 35.4 bits (80), Expect = 0.13
Identities = 46/218 (21%), Positives = 90/218 (41%), Gaps = 26/218 (11%)
Query: 6 ELWDQFEVLERHTQWG----LDLLDRYVKFVKERTEVEQAYAK------QLRSLVKKYLP 55
ELW E ER + LD +R + T + K QL+S V++ +
Sbjct: 1690 ELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1749
Query: 56 K-RPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERK 114
+ R A++ + + + L++ D + E + +NL V + + +
Sbjct: 1750 ESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV----KDLQHRLDEAEQ 1805
Query: 115 MHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKA-- 172
+ + G++ Q+LE ++LE ++ EA K + ER +++ + K
Sbjct: 1806 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVL 1865
Query: 173 -------KQQAHLRSH--MAEESKNEYAAQLQRFNRDQ 201
K QA ++S+ AEE++ + A L +F + Q
Sbjct: 1866 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQ 1903
Score = 31.2 bits (69), Expect = 2.5
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 12/110 (10%)
Query: 325 KKNKTVVTEDFSHLPPEQQRKRLQ------QQLEERSRELQKEVDQR-----EALKKMKD 373
KKN +D H E ++ L+ Q+LE R REL+ EV+ EA+K ++
Sbjct: 1786 KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRK 1845
Query: 374 VYEKTPQMGDPASLEPQIAETLSN-IERLKLEVQKYEAWLAEAESRVLSN 422
+ ++ + + L + +++L+ +V+ Y+ EAE + +N
Sbjct: 1846 HERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNAN 1895
Score = 30.4 bits (67), Expect = 4.3
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 3/115 (2%)
Query: 354 RSRELQKEV-DQREALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWL 412
+S E +KE+ +E +K KD K+ LE ++ L L+L+VQ L
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSE--AKRKELEEKMVTLLKEKNDLQLQVQSEADSL 901
Query: 413 AEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQD 467
A+AE R + + A+ + A + N+ K E+ SE +D
Sbjct: 902 ADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKD 956
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.0 bits (110), Expect = 4e-05
Identities = 78/394 (19%), Positives = 152/394 (38%), Gaps = 76/394 (19%)
Query: 96 VRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTA 155
V+ L++T+ +EM Q ++ Q+ + QQ+ EN K+LE + + ++ Q
Sbjct: 841 VKPLLQVTRQEEEM-QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 156 ERLDQDINATKADVEKAKQQAHLRSHMAE---ESKNEYAAQLQRFNRDQAHFYFSQMPQI 212
L + + + KQ+ H E E + + QLQ + A Q+
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ-------QM 952
Query: 213 FDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELH 272
D + ++E A R + +LE KV A A K + +L+
Sbjct: 953 LDLEEQLEEEEAAR--------QKLQLE------------KVTAEAKIKKLEDEILV--- 989
Query: 273 KSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVT 332
++ ++ R + + + E ++ TK K++++++
Sbjct: 990 ---------MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK---LKNKHESMIS 1037
Query: 333 EDFSHLPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIA 392
E LE R L+KE R+ L+K+K E GD + QIA
Sbjct: 1038 E-----------------LEVR---LKKEEKSRQELEKLKRKLE-----GDASDFHEQIA 1072
Query: 393 ETLSNIERLKLEVQKYEAWLAEAESRV---LSNRGDSLSRHARPPDPPASAPPDSSSNSA 449
+ + I LK+++ K E L A +R+ ++ + ++L + + D S A
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132
Query: 450 SQDTKESSEEPPSEESQDTPIYTEFDEDFEEEPT 483
+++ E + EE + + TE ++ + T
Sbjct: 1133 ARNKAEKQKRDLGEELE--ALKTELEDTLDSTAT 1164
Score = 42.0 bits (97), Expect = 0.001
Identities = 92/449 (20%), Positives = 166/449 (36%), Gaps = 108/449 (24%)
Query: 25 LDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFA 84
L + V+ E ++ + K++ +L ++Y K A D E ++ Q + L V D
Sbjct: 1380 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL--VVDLD 1437
Query: 85 GQRELVA----------------ENLSVRVCLELTKYSQEMKQERKMHF------QEGRR 122
QR+LV+ +N+S + E + E +++ +E
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497
Query: 123 AQQQLENGFK---------------------QLENSKRKFERDCREAEKAAQTAERLDQD 161
A+++LE K +LE SKR E + E+ E L+ +
Sbjct: 1498 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE---TQMEEMKTQLEELEDE 1554
Query: 162 INAT-------KADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFD 214
+ AT + +++ K Q +E E QLQR Q H Y +++
Sbjct: 1555 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR----QLHEYETELE---- 1606
Query: 215 KLQDMDERRATRLGAGYGLLSEAELEVVPIIA-KCLEGMKVAANAVDPKNDSHVLIELHK 273
DER+ L A E +L+ + + A ++G + A +
Sbjct: 1607 -----DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-------------- 1647
Query: 274 SGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTE 333
R + +DF + + A + R E+ + K+ + + + E
Sbjct: 1648 ----RKLQAQMKDFQRELEDARA---------SRDEIFATAKENEKKAKSLEADLMQLQE 1694
Query: 334 DFSHLPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAE 393
D + E+ RK+ + EE + EL + R AL+ EK A LE ++ E
Sbjct: 1695 DLA--AAERARKQADLEKEELAEELASSLSGRNALQD-----EKRRLEARIAQLEEELEE 1747
Query: 394 TLSNIERLKLEVQKYEAWLAEAESRVLSN 422
N+E + V+K A ++ LSN
Sbjct: 1748 EQGNMEAMSDRVRK-----ATQQAEQLSN 1771
Score = 38.9 bits (89), Expect = 0.012
Identities = 100/483 (20%), Positives = 188/483 (38%), Gaps = 64/483 (13%)
Query: 62 DPESKFSQQQSFVQILQE-----VNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMH 116
D S SQ Q ++LQE +N R+L E S++ L+ E KQ + H
Sbjct: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD---EEMEAKQNLERH 1365
Query: 117 FQ-------EGRRAQQQLENGFKQLENSKRKFERDCREA-----EKAA------QTAERL 158
+ ++ Q + + LE K++F+++ EKAA +T RL
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 159 DQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQD 218
Q+++ D++ +Q L S++ E K QL ++ + Y + + + ++
Sbjct: 1426 QQELDDLVVDLDNQRQ---LVSNL--EKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
Query: 219 MDERRATRLGA-GYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFA 277
+ + + A L ++ ELE + K E + ++ D + H EL KS
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKA-EMEDLVSSKDDVGKNVH---ELEKS--K 1534
Query: 278 RPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSH 337
R + + E+ + + + R E+ G+ + + D +
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK-------GQFERDLQARDEQN 1587
Query: 338 LPPEQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQIAETLSN 397
E++R++LQ+QL E EL+ E QR K E GD LE Q +
Sbjct: 1588 ---EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE-----GDLKDLELQADSAIKG 1639
Query: 398 IERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHARPPDPPASAPPDSSSNSASQDTKESS 457
E +++K +A + + + + +R +R + + + S D +
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELED------ARASRDEIFATAKENEKKAKSLEADLMQLQ 1693
Query: 458 EEPPSEESQDTPIYTEFDEDFEEEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEED 517
E+ + E E E+ EE S + A+ + E I+ E E +EE+
Sbjct: 1694 EDLAAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEE----LEEE 1748
Query: 518 KGD 520
+G+
Sbjct: 1749 QGN 1751
Score = 36.6 bits (83), Expect = 0.061
Identities = 92/413 (22%), Positives = 173/413 (41%), Gaps = 59/413 (14%)
Query: 14 LERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSF 73
LE G L K ++ ++E+ ++ + K L K A E+K + +
Sbjct: 931 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA----EAKIKKLEDE 986
Query: 74 VQILQEVND-FAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFK 132
+ ++ + N+ + +R+L+ E +S +LT E +++ K + + + E+
Sbjct: 987 ILVMDDQNNKLSKERKLLEERIS-----DLTTNLAEEEEKAK----NLTKLKNKHESMIS 1037
Query: 133 QLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAA 192
+LE +K E+ +E EK + E D + AD++ Q A L+ +A++ + E A
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAELKMQLAKK-EEELQA 1094
Query: 193 QLQRFNRD--QAHFYFSQMPQ----IFDKLQDMDERRATR---------LGAGYGLLSEA 237
L R + + Q + ++ + I D +D+D RA R LG L +
Sbjct: 1095 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL-KT 1153
Query: 238 ELEVV--------PIIAKCLEGMKVAANAVDPKNDSH-VLIELHKSGFARPGDVEFEDFS 288
ELE + AK + + V A+D + SH ++ + A+ + E
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1213
Query: 289 Q-PMNRAPSDSSLGT----PSDGRPELRGPGRSRTKRWPFGKKNKTVVTEDFSHLPPEQQ 343
Q +A D + T +D ELR G+++ + KK + V E S
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC---SD 1270
Query: 344 RKRLQQQLEERSRELQKEVD---------QREALKKMKDVYEKTPQMGDPASL 387
+R + +L ++ +LQ EV+ + +A+K KDV + Q+ D L
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1323
Score = 36.2 bits (82), Expect = 0.079
Identities = 61/338 (18%), Positives = 132/338 (39%), Gaps = 48/338 (14%)
Query: 101 ELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQ 160
E+T + + +E + H + + +Q+ ++L +F+R +K QT E+ +
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 161 DINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMD 220
D+ + +AKQ+ + E E ++ R +A +L D
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA------------ELNDKV 1282
Query: 221 ERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPG 280
+ + + G+L+EAE K ++ K A+ D+ L++
Sbjct: 1283 HKLQNEVESVTGMLNEAE-------GKAIKLAKDVASLSSQLQDTQELLQ---------- 1325
Query: 281 DVEFEDFSQPMNRA-------PSDSSLGTPSDGRPELRGPGRSRTKRWPFGKKNKTVVTE 333
E+ Q +N + +SL D E + + +
Sbjct: 1326 ----EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ 1381
Query: 334 DFSHLPP--EQQRKRLQQQLEERSRELQKEVDQREALKKMKDVYEKTPQMGDPASLEPQI 391
DF+ E+ +KR Q+++E +++ +++ + L+K K+ ++ ++ D
Sbjct: 1382 DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ--ELDDLVVDLDNQ 1439
Query: 392 AETLSNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSR 429
+ +SN+E+ + +K++ LAE E + S D R
Sbjct: 1440 RQLVSNLEK---KQRKFDQLLAE-EKNISSKYADERDR 1473
Score = 32.7 bits (73), Expect = 0.87
Identities = 23/122 (18%), Positives = 61/122 (50%), Gaps = 7/122 (5%)
Query: 64 ESKFSQQQSFVQILQEVNDF-AGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRR 122
E+K +Q + Q+ QE + A + L ++ ++ L + ++M ++ K ++G
Sbjct: 1820 EAKIAQLEE--QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA 1877
Query: 123 AQQQLENGFKQLENSKRKFERDCR----EAEKAAQTAERLDQDINATKADVEKAKQQAHL 178
+QL+ ++ E ++ + R E ++A ++ E + +++NA K+ + + + + +
Sbjct: 1878 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFV 1937
Query: 179 RS 180
S
Sbjct: 1938 PS 1939
Score = 32.0 bits (71), Expect = 1.5
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 8/139 (5%)
Query: 32 VKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVA 91
V + E QA +L+ ++ + E K SQ +LQE + EL A
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE--QLQAETELYA 904
Query: 92 ENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKA 151
E +RV L K QE+ E +H E R ++ E+ +QL+ ++K + + E+
Sbjct: 905 EAEEMRVRLAAKK--QEL--EEILHEMEARLEEE--EDRGQQLQAERKKMAQQMLDLEEQ 958
Query: 152 AQTAERLDQDINATKADVE 170
+ E Q + K E
Sbjct: 959 LEEEEAARQKLQLEKVTAE 977
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,093,967
Number of Sequences: 37866
Number of extensions: 1105842
Number of successful extensions: 12229
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 179
Number of HSP's successfully gapped in prelim test: 719
Number of HSP's that attempted gapping in prelim test: 9311
Number of HSP's gapped (non-prelim): 3213
length of query: 545
length of database: 18,247,518
effective HSP length: 107
effective length of query: 438
effective length of database: 14,195,856
effective search space: 6217784928
effective search space used: 6217784928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.