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Search of human proteins with 11342670
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11342670 azurocidin 1 preproprotein [Homo sapiens]
(251 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11342670 azurocidin 1 preproprotein [Homo sapiens] 511 e-145
gi|4503549 neutrophil elastase preproprotein [Homo sapiens] 199 2e-51
gi|71361688 myeloblastin [Homo sapiens] 192 3e-49
gi|47551347 protease, serine-like 1 [Homo sapiens] 137 7e-33
gi|42544239 complement factor D preproprotein [Homo sapiens] 131 5e-31
gi|4885369 granzyme M precursor [Homo sapiens] 129 3e-30
gi|5453676 granzyme A precursor [Homo sapiens] 126 2e-29
gi|4503149 cathepsin G preproprotein [Homo sapiens] 123 2e-28
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 122 4e-28
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 118 4e-27
gi|15529990 granzyme H [Homo sapiens] 118 6e-27
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 117 9e-27
gi|4504235 granzyme K precursor [Homo sapiens] 115 4e-26
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 115 5e-26
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 114 6e-26
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 114 1e-25
gi|221625528 granzyme B precursor [Homo sapiens] 113 2e-25
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 109 2e-24
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 109 2e-24
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 109 2e-24
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 106 2e-23
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 106 2e-23
gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens] 106 2e-23
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 105 3e-23
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 104 8e-23
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 104 8e-23
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 104 8e-23
gi|11496281 kallikrein 13 precursor [Homo sapiens] 103 2e-22
gi|4504383 HGF activator preproprotein [Homo sapiens] 101 5e-22
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 100 1e-21
>gi|11342670 azurocidin 1 preproprotein [Homo sapiens]
Length = 251
Score = 511 bits (1316), Expect = e-145
Identities = 251/251 (100%), Positives = 251/251 (100%)
Query: 1 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR 60
MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR
Sbjct: 1 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR 60
Query: 61 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ 120
FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ
Sbjct: 61 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ 120
Query: 121 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC 180
LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC
Sbjct: 121 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC 180
Query: 181 RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWID 240
RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWID
Sbjct: 181 RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWID 240
Query: 241 GVLNNPGPGPA 251
GVLNNPGPGPA
Sbjct: 241 GVLNNPGPGPA 251
>gi|4503549 neutrophil elastase preproprotein [Homo sapiens]
Length = 267
Score = 199 bits (505), Expect = 2e-51
Identities = 111/254 (43%), Positives = 150/254 (59%), Gaps = 8/254 (3%)
Query: 3 RLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
RL L L L A G++ +IVGGR+ARP +PF+ S+Q +G HFCG LI FV
Sbjct: 6 RLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFV 65
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122
M+AA C + N VVLGA++L RRE +RQ F++ + ENGYDP LND+++LQL+
Sbjct: 66 MSAAHCVANVNVRAVRVVLGAHNLSRRE-PTRQVFAVQRIFENGYDPVNLLNDIVILQLN 124
Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP 182
A + ++V + LP Q + G +C GWG ++ + +NVTV CR
Sbjct: 125 GSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRR 183
Query: 183 NNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWID 240
+NVCT V R+ G+C GD G+PLVC GL HG+ASF G C G PD F VA F +WID
Sbjct: 184 SNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWID 243
Query: 241 GVL----NNPGPGP 250
++ +NP P P
Sbjct: 244 SIIQRSEDNPCPHP 257
>gi|71361688 myeloblastin [Homo sapiens]
Length = 256
Score = 192 bits (487), Expect = 3e-49
Identities = 105/241 (43%), Positives = 150/241 (62%), Gaps = 7/241 (2%)
Query: 8 ALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMT 64
AL + LLA +G++ +IVGG +A+P P++AS+Q N G HFCGG LIH FV+T
Sbjct: 9 ALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68
Query: 65 AASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDRE 124
AA C + + VVLGA+++R +E ++Q FS++ + N YD + LND++L+QL
Sbjct: 69 AAHCLRDIPQRLVNVVLGAHNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSP 127
Query: 125 ANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN 184
ANL++SV + LP Q+ V GT+C GWG + ++ + +NVTV CRP+N
Sbjct: 128 ANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCRPHN 186
Query: 185 VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGV 242
+CT V R+ GIC GD G PL+C+G+ G+ SF + C PDFFTRVAL+ DWI
Sbjct: 187 ICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRST 246
Query: 243 L 243
L
Sbjct: 247 L 247
>gi|47551347 protease, serine-like 1 [Homo sapiens]
Length = 283
Score = 137 bits (346), Expect = 7e-33
Identities = 91/239 (38%), Positives = 131/239 (54%), Gaps = 16/239 (6%)
Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86
I+GG + P P++AS++ G+H CGG L+ AR+V++AA CF ++ VVLGA+ L
Sbjct: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93
Query: 87 RRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA-TVE 144
E ++Q F I +++ + Y P + ND+ LL+L+ A L +V +L LP + A
Sbjct: 94 STAE-PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPT 152
Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----RPNNVCTGVLTRRG-----G 195
AGTRC+VAGWG L V V D C + + T + TR G G
Sbjct: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212
Query: 196 ICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL--NNPGPGP 250
C+ D G PLVC AHG+ SFS CG + PD +T+V+ F WI V+ ++P PGP
Sbjct: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGP 271
>gi|42544239 complement factor D preproprotein [Homo sapiens]
Length = 253
Score = 131 bits (330), Expect = 5e-31
Identities = 86/251 (34%), Positives = 119/251 (47%), Gaps = 14/251 (5%)
Query: 3 RLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
RL VL LL ++ + P I+GGR+A P++AS+Q G H CGG L+ ++V
Sbjct: 6 RLAVLVLLG----AAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWV 61
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122
++AA C + G V+LGA+ L + E R + ++ P +DL+LLQL
Sbjct: 62 LSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLS 121
Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP 182
+A L +V LP + V GT C VAGWG GR + V + V C
Sbjct: 122 EKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNR 181
Query: 183 NNVCTGVLT--------RRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRV 232
G +T R C GD G PLVC G+ GV + CG + P +TRV
Sbjct: 182 RTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRV 241
Query: 233 ALFRDWIDGVL 243
A + WID VL
Sbjct: 242 ASYAAWIDSVL 252
>gi|4885369 granzyme M precursor [Homo sapiens]
Length = 257
Score = 129 bits (323), Expect = 3e-30
Identities = 92/250 (36%), Positives = 123/250 (49%), Gaps = 21/250 (8%)
Query: 6 VLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTA 65
V +LL L + GSS I+GGR+ P P++AS+Q G H CGG L+H ++V+TA
Sbjct: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64
Query: 66 ASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENG-YDPQQNL-NDLMLLQLDR 123
A C +Q +VLG + L TF I + ++ Y P L NDL LLQLD
Sbjct: 65 AHCL-AQRMAQLRLVLGLHTLD----SPGLTFHIKAAIQHPRYKPVPALENDLALLQLDG 119
Query: 124 EANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-- 181
+ + ++ L LP + V AGTRC +AGWG GGRLSR R +++ V C
Sbjct: 120 KVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS 179
Query: 182 --------PNNVCTGVLTRRGGICNGDGGTPLVC--EGLAHGVASFSLGPCGR--GPDFF 229
P+ VC ++ C GD G PLVC + GV SFS C P
Sbjct: 180 RFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVA 239
Query: 230 TRVALFRDWI 239
T VA + WI
Sbjct: 240 TAVAPYVSWI 249
>gi|5453676 granzyme A precursor [Homo sapiens]
Length = 262
Score = 126 bits (317), Expect = 2e-29
Identities = 79/218 (36%), Positives = 104/218 (47%), Gaps = 18/218 (8%)
Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86
I+GG + P P++ + + C GALI +V+TAA C ++ S V+LGA+ +
Sbjct: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR---SQVILGAHSI 85
Query: 87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 146
R E + YDP DL LLQL +A + VTIL LP + V+ G
Sbjct: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 145
Query: 147 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN------------VCTGVLTRRG 194
T CQVAGWG + S R VN+T+ C N VC G L
Sbjct: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205
Query: 195 GICNGDGGTPLVCEGLAHGVASFSL-GPCG--RGPDFF 229
CNGD G+PL+CEG+ GV SF L CG RGP +
Sbjct: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243
>gi|4503149 cathepsin G preproprotein [Homo sapiens]
Length = 255
Score = 123 bits (308), Expect = 2e-28
Identities = 85/247 (34%), Positives = 122/247 (49%), Gaps = 25/247 (10%)
Query: 6 VLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQ---GRHFCGGALIHARFV 62
+L LLA LL + +I+GGR++RP P++A +Q Q G+ CGG L+ FV
Sbjct: 4 LLLLLAFLLPTGAEAG----EIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFV 59
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122
+TAA C+ S V LGA++++RRE + + ++ Y+ + ND+MLLQL
Sbjct: 60 LTAAHCWGSN----INVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLS 115
Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWG--SQRSGGRLSRFPRFVNVTVTPEDQC 180
R +V + LP + GT C VAGWG S R G + R V + V + QC
Sbjct: 116 RRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRG---TDTLREVQLRVQRDRQC 172
Query: 181 --------RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRV 232
+C G R GD G PL+C +AHG+ S+ G P+ FTRV
Sbjct: 173 LRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKS-SGVPPEVFTRV 231
Query: 233 ALFRDWI 239
+ F WI
Sbjct: 232 SSFLPWI 238
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 122 bits (305), Expect = 4e-28
Identities = 84/242 (34%), Positives = 129/242 (53%), Gaps = 25/242 (10%)
Query: 23 PLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLG 82
P IVGG + ++P+ AS+Q +GRH CGGALI R+V+TAA CFQ + +++ VL
Sbjct: 573 PSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDS--MASTVLW 630
Query: 83 AYDLRRRERQSR----QTFSISSMSENGYDPQQNLN-DLMLLQLDREANLTSSVTILPLP 137
L + + SR +F +S + + Y + + + D+ LLQLD +++V + LP
Sbjct: 631 TVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLP 690
Query: 138 LQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGV 189
++ E G C + GWG+ R GG +S + V+V + P+D C P +C G
Sbjct: 691 ARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGY 750
Query: 190 LTRRGGICNGDGGTPLVCEGLA-----HGVASFSLGPCGRGPDFF---TRVALFRDWIDG 241
+ C GD G PLVC+ L+ G+ S+ LG CGR P++F TR+ WI
Sbjct: 751 RKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLG-CGR-PNYFGVYTRITGVISWIQQ 808
Query: 242 VL 243
V+
Sbjct: 809 VV 810
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 118 bits (296), Expect = 4e-27
Identities = 77/243 (31%), Positives = 119/243 (48%), Gaps = 20/243 (8%)
Query: 9 LLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASC 68
L+ G+ S +GS I+ G P P+ A++ + FC G L+H ++V++AA C
Sbjct: 15 LILGVAGSLVSGSCS--QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72
Query: 69 FQSQNPGVSTVVLGAYDLRRRERQSRQTFSIS-SMSENGYDPQQNLNDLMLLQLDREANL 127
FQ+ T+ LG + L + Q S S+ Y+ NDLML++LD ++
Sbjct: 73 FQNSY----TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDE--SV 126
Query: 128 TSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC------- 180
+ S TI + + + AG C V+GWG + GR+ + VNV+V E+ C
Sbjct: 127 SESDTIRSISIASQCPTAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPL 185
Query: 181 -RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRD 237
P+ C G + CNGD G PL+C G G+ SF PCG+ P +T + F +
Sbjct: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245
Query: 238 WID 240
WI+
Sbjct: 246 WIE 248
>gi|15529990 granzyme H [Homo sapiens]
Length = 246
Score = 118 bits (295), Expect = 6e-27
Identities = 82/243 (33%), Positives = 122/243 (50%), Gaps = 21/243 (8%)
Query: 9 LLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTA 65
LL L + AG+ +I+GG +A+P P++A +Q + R CGG L+ FV+TA
Sbjct: 6 LLLAFLLTPGAGTE---EIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTA 62
Query: 66 ASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREA 125
A C S V LGA++++ +ER + + Y+P+ ND+MLLQL+R+A
Sbjct: 63 AHCQGSS----INVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKA 118
Query: 126 NLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC----- 180
T++V L LP A V+ G C VAGWG S L+ + V +TV + QC
Sbjct: 119 KWTTAVRPLRLPSSKAQVKPGQLCSVAGWG-YVSMSTLATTLQEVLLTVQKDCQCERLFH 177
Query: 181 ----RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFR 236
R +C G + GD G PLVC+ +A G+ S+ G P + +V+ F
Sbjct: 178 GNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYG-NKKGTPPGVYIKVSHFL 236
Query: 237 DWI 239
WI
Sbjct: 237 PWI 239
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 117 bits (293), Expect = 9e-27
Identities = 81/259 (31%), Positives = 131/259 (50%), Gaps = 30/259 (11%)
Query: 4 LTVLALLAGLLASSRAGSSPLLDIVGG----RKARPRQFPFLASIQNQGRHFCGGALIHA 59
LT L +LA + S+ + I+GG R ++P Q LA + R CGGAL+
Sbjct: 21 LTALQVLAIAMTQSQEDENK---IIGGHTCTRSSQPWQAALLAGPRR--RFLCGGALLSG 75
Query: 60 RFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLL 119
++V+TAA C + + V LG ++LRR E + + ++ Y+ + + NDLMLL
Sbjct: 76 QWVITAAHCGRP----ILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLL 131
Query: 120 QLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFP---RFVNVTVTP 176
QL + A + +V P+ + A GT C+V+GWG+ S ++R+P + VN+ ++P
Sbjct: 132 QLQQPARIGRAVR--PIEVTQACASPGTSCRVSGWGTISSP--IARYPASLQCVNINISP 187
Query: 177 EDQCR--------PNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--P 226
++ C+ P VC GV C GD G PLVC G G+ S+ + C P
Sbjct: 188 DEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYP 247
Query: 227 DFFTRVALFRDWIDGVLNN 245
+T + +R WI+ + +
Sbjct: 248 GVYTNLCKYRSWIEETMRD 266
>gi|4504235 granzyme K precursor [Homo sapiens]
Length = 264
Score = 115 bits (288), Expect = 4e-26
Identities = 77/209 (36%), Positives = 106/209 (50%), Gaps = 21/209 (10%)
Query: 25 LDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS-TVVLGA 83
++I+GG++ P PF+ASIQ G H CGG LI ++V+TAA C G S TVVLGA
Sbjct: 25 MEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGA 84
Query: 84 YDLRRRERQSRQTFSISS---MSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQN 140
+ L + E S+QT I S DPQ ND+ML++L A L V +L +
Sbjct: 85 HSLSKNE-ASKQTLEIKKFIPFSRVTSDPQS--NDIMLVKLQTAAKLNKHVKMLHI-RSK 140
Query: 141 ATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCRPNN------------VCT 187
++ +GT+C+V GWG+ R S R V VTV C + VC
Sbjct: 141 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 200
Query: 188 GVLTRRGGICNGDGGTPLVCEGLAHGVAS 216
G + C GD G PL+C+G+ H + S
Sbjct: 201 GDAKGQKDSCKGDSGGPLICKGVFHAIVS 229
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 115 bits (287), Expect = 5e-26
Identities = 76/252 (30%), Positives = 128/252 (50%), Gaps = 25/252 (9%)
Query: 13 LLASSRAGSSPLLD--IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQ 70
LL + AG S + ++GG + +P P+ A++ + CGG L+ +V+TAA C +
Sbjct: 17 LLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKK 76
Query: 71 SQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE---NGYDPQQNLNDLMLLQLDREANL 127
+ TV LG + L+ ++ ++ + S+ N D + + +DLMLLQL +A+L
Sbjct: 77 PKY----TVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
Query: 128 TSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQCR--- 181
S V P+ L + + G +C V+GWG+ S FP +N V + P+ +C
Sbjct: 133 GSKVK--PISLADHCTQPGQKCTVSGWGTVTSPRE--NFPDTLNCAEVKIFPQKKCEDAY 188
Query: 182 PNNVCTGVL----TRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALF 235
P + G++ ++ C GD G PLVC+G G+ S+ PCGR P +T + +
Sbjct: 189 PGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRY 248
Query: 236 RDWIDGVLNNPG 247
DWI ++ + G
Sbjct: 249 LDWIKKIIGSKG 260
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 114 bits (286), Expect = 6e-26
Identities = 82/253 (32%), Positives = 127/253 (50%), Gaps = 33/253 (13%)
Query: 20 GSSPLL--DIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVS 77
G++PL+ IVGG + P+ + ++GR CGG L+H ++V+TAA C +++ S
Sbjct: 16 GAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----S 71
Query: 78 TVVLGAYDLRRRERQSRQTFSIS----------SMSENGY--DPQQNLNDLMLLQLDREA 125
++LG + L E + Q F +S S+ +N + + +DLMLL+L A
Sbjct: 72 VILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPA 130
Query: 126 NLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLS-RFPRFVNVTVTPEDQC---R 181
LT +V ++ LP Q + GT C +GWGS L+ + + V++ V D C
Sbjct: 131 ELTDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH 188
Query: 182 PNNV-----CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVAL 234
P V C G T C+GD G PLVC G+ G+ S+ PC P +T+V
Sbjct: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVH 248
Query: 235 FRDWI-DGVLNNP 246
+R WI D ++ NP
Sbjct: 249 YRKWIKDTIVANP 261
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 114 bits (284), Expect = 1e-25
Identities = 71/236 (30%), Positives = 121/236 (51%), Gaps = 23/236 (9%)
Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86
++GG + +P P+ A++ + CGG L+ +V+TAA C + + TV LG + L
Sbjct: 78 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKY----TVRLGDHSL 133
Query: 87 RRRERQSRQTFSISSMSE---NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 143
+ ++ ++ + S+ N D + + +DLMLLQL +A+L S V P+ L +
Sbjct: 134 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVK--PISLADHCT 191
Query: 144 EAGTRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQCR---PNNVCTGVL----TRR 193
+ G +C V+GWG+ S FP +N V + P+ +C P + G++ ++
Sbjct: 192 QPGQKCTVSGWGTVTSPRE--NFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG 249
Query: 194 GGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLNNPG 247
C GD G PLVC+G G+ S+ PCGR P +T + + DWI ++ + G
Sbjct: 250 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 305
>gi|221625528 granzyme B precursor [Homo sapiens]
Length = 247
Score = 113 bits (282), Expect = 2e-25
Identities = 82/246 (33%), Positives = 121/246 (49%), Gaps = 21/246 (8%)
Query: 6 VLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFV 62
+L LLA LL RA + +I+GG +A+P P++A + + CGG LI FV
Sbjct: 4 ILLLLAFLLLP-RADAG---EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFV 59
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122
+TAA C+ S V LGA++++ +E + + Y+P+ ND+MLLQL+
Sbjct: 60 LTAAHCWGSS----INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLE 115
Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP 182
R+A T +V L LP A V+ G C VAGWG G+ S + V +TV + +C
Sbjct: 116 RKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES 175
Query: 183 N---------NVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVA 233
+ +C G + GD G PLVC +A G+ S+ G P T+V+
Sbjct: 176 DLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN-GMPPRACTKVS 234
Query: 234 LFRDWI 239
F WI
Sbjct: 235 SFVHWI 240
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 109 bits (273), Expect = 2e-24
Identities = 78/258 (30%), Positives = 122/258 (47%), Gaps = 28/258 (10%)
Query: 3 RLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
+L +LAL GL+ I+ G + +P P+ A++ + R CG LI R++
Sbjct: 5 QLILLALATGLVGGETR-------IIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWL 57
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYD----PQQNLNDLML 118
+TAA C + + V LG ++L++ E + + S G++ + + ND+ML
Sbjct: 58 LTAAHCLKPR----YIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIML 113
Query: 119 LQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPE 177
+++ ++T +V PL L + V AGT C ++GWGS S RL R N+T+
Sbjct: 114 VKMASPVSITWAVR--PLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 171
Query: 178 DQCR---PNN-----VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPD 227
+C P N VC V C GD G PLVC G+ S+ PC R P
Sbjct: 172 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 231
Query: 228 FFTRVALFRDWIDGVLNN 245
+T+V + DWI + N
Sbjct: 232 VYTKVCKYVDWIQETMKN 249
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 109 bits (273), Expect = 2e-24
Identities = 78/258 (30%), Positives = 122/258 (47%), Gaps = 28/258 (10%)
Query: 3 RLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
+L +LAL GL+ I+ G + +P P+ A++ + R CG LI R++
Sbjct: 37 QLILLALATGLVGGETR-------IIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWL 89
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYD----PQQNLNDLML 118
+TAA C + + V LG ++L++ E + + S G++ + + ND+ML
Sbjct: 90 LTAAHCLKPR----YIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIML 145
Query: 119 LQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPE 177
+++ ++T +V PL L + V AGT C ++GWGS S RL R N+T+
Sbjct: 146 VKMASPVSITWAVR--PLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
Query: 178 DQCR---PNN-----VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPD 227
+C P N VC V C GD G PLVC G+ S+ PC R P
Sbjct: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
Query: 228 FFTRVALFRDWIDGVLNN 245
+T+V + DWI + N
Sbjct: 264 VYTKVCKYVDWIQETMKN 281
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 109 bits (273), Expect = 2e-24
Identities = 78/258 (30%), Positives = 122/258 (47%), Gaps = 28/258 (10%)
Query: 3 RLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
+L +LAL GL+ I+ G + +P P+ A++ + R CG LI R++
Sbjct: 5 QLILLALATGLVGGETR-------IIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWL 57
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYD----PQQNLNDLML 118
+TAA C + + V LG ++L++ E + + S G++ + + ND+ML
Sbjct: 58 LTAAHCLKPR----YIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIML 113
Query: 119 LQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPE 177
+++ ++T +V PL L + V AGT C ++GWGS S RL R N+T+
Sbjct: 114 VKMASPVSITWAVR--PLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 171
Query: 178 DQCR---PNN-----VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPD 227
+C P N VC V C GD G PLVC G+ S+ PC R P
Sbjct: 172 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 231
Query: 228 FFTRVALFRDWIDGVLNN 245
+T+V + DWI + N
Sbjct: 232 VYTKVCKYVDWIQETMKN 249
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 106 bits (265), Expect = 2e-23
Identities = 78/254 (30%), Positives = 123/254 (48%), Gaps = 24/254 (9%)
Query: 4 LTVLALLAGLLASSRAGSSPLLD-IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
L L +L LA AG D I+ G P+ ++ + + CGG L++ R+V
Sbjct: 6 LLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWV 65
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122
+TAA C ++ TV LG+ L +R++++ + S GY Q ++NDLML++L+
Sbjct: 66 LTAAHCKMNEY----TVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLN 119
Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFV-----------N 171
+A L+S V + LP + GT C V+GWG+ S FP + +
Sbjct: 120 SQARLSSMVKKVRLP--SRCEPPGTTCTVSGWGTTTSPD--VTFPSDLMCVDVKLISPQD 175
Query: 172 VTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFF 229
T +D + +C G+ + CNGD G PLVC G G+ S+ PCG+ P +
Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235
Query: 230 TRVALFRDWIDGVL 243
T+V F WI+ +
Sbjct: 236 TQVCKFTKWINDTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 106 bits (265), Expect = 2e-23
Identities = 78/254 (30%), Positives = 123/254 (48%), Gaps = 24/254 (9%)
Query: 4 LTVLALLAGLLASSRAGSSPLLD-IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFV 62
L L +L LA AG D I+ G P+ ++ + + CGG L++ R+V
Sbjct: 6 LLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWV 65
Query: 63 MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLD 122
+TAA C ++ TV LG+ L +R++++ + S GY Q ++NDLML++L+
Sbjct: 66 LTAAHCKMNEY----TVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLN 119
Query: 123 REANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFV-----------N 171
+A L+S V + LP + GT C V+GWG+ S FP + +
Sbjct: 120 SQARLSSMVKKVRLP--SRCEPPGTTCTVSGWGTTTSPD--VTFPSDLMCVDVKLISPQD 175
Query: 172 VTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFF 229
T +D + +C G+ + CNGD G PLVC G G+ S+ PCG+ P +
Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235
Query: 230 TRVALFRDWIDGVL 243
T+V F WI+ +
Sbjct: 236 TQVCKFTKWINDTM 249
>gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens]
Length = 247
Score = 106 bits (265), Expect = 2e-23
Identities = 80/252 (31%), Positives = 118/252 (46%), Gaps = 22/252 (8%)
Query: 4 LTVLALLAGLLAS-SRAGSSPLLDIVGGRKARPRQFPFLASIQ----NQGRHFCGGALIH 58
L L LL LL S + AG +I+GG + +P P++A ++ N FCGG LI
Sbjct: 3 LLPLPLLLFLLCSRAEAG-----EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIR 57
Query: 59 ARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLML 118
FV+TAA C TV LGA+++ E ++ I Y+ +D+ML
Sbjct: 58 RNFVLTAAHCAGRS----ITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIML 113
Query: 119 LQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED 178
L+L +A+LT +V LP P Q V G C+VAGWG S + V + +
Sbjct: 114 LKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQ 173
Query: 179 QC-------RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTR 231
C +C G + GD G PL+C G+A G+ S+ + P FTR
Sbjct: 174 ACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKPPAVFTR 232
Query: 232 VALFRDWIDGVL 243
++ +R WI+ +L
Sbjct: 233 ISHYRPWINQIL 244
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 105 bits (263), Expect = 3e-23
Identities = 79/263 (30%), Positives = 123/263 (46%), Gaps = 31/263 (11%)
Query: 9 LLAGLLASSRAGSSPLLD--IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAA 66
+L+ L+ G+ PL+ IVGG + P+ ++ + G CGG L+H ++V+TAA
Sbjct: 5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
Query: 67 SCFQSQNPGVSTVVLGAYDLRRRERQSRQT----------FSISSMSENGYDPQQNLN-D 115
C + S V LG ++L E ++ +++S + P ++ + D
Sbjct: 65 HCLKKN----SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 116 LMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLS-RFPRFVNVTV 174
LMLL+L A +T V +L LP Q + GT C +GWGS L R + V++ +
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHL 178
Query: 175 TPEDQCRPNN--------VCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--R 224
D C +C G+ T C GD G PLVC G+ G+ S+ PC
Sbjct: 179 LSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPE 238
Query: 225 GPDFFTRVALFRDWI-DGVLNNP 246
P +T+V +R WI D + NP
Sbjct: 239 KPAVYTKVVHYRKWIKDTIAANP 261
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 104 bits (259), Expect = 8e-23
Identities = 77/228 (33%), Positives = 111/228 (48%), Gaps = 17/228 (7%)
Query: 27 IVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCF-QSQNPGVSTVVLGAY 84
IVGG A P +P+ S++ + G+HFCGG LI +V+TAA C +S P V+LGA+
Sbjct: 1820 IVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAH 1879
Query: 85 DLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVE 144
E ++ +S +P Q D+ LL+L R A +T V LP + V
Sbjct: 1880 QEVNLESHVQEI----EVSRLFLEPTQ--ADIALLKLSRPAVITDKVMPACLPSPDYMVT 1933
Query: 145 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP-NNVCTGVLTRRGGICNGDGGT 203
A T C + GWG + G + + + V + C +C L R C GD G
Sbjct: 1934 ARTECYITGWG-ETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLARGTDSCQGDSGG 1992
Query: 204 PLVC----EGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 245
PLVC + + GV S+ LG C R P + RV+ F WI+G++ N
Sbjct: 1993 PLVCFEKDKYILQGVTSWGLG-CARPNKPGVYARVSRFVTWIEGMMRN 2039
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 104 bits (259), Expect = 8e-23
Identities = 76/249 (30%), Positives = 111/249 (44%), Gaps = 29/249 (11%)
Query: 4 LTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVM 63
+ VL+L+A A + +V G P+ A++ G CGG LIH +V+
Sbjct: 5 MVVLSLIAAAWAEEQN------KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVL 58
Query: 64 TAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDR 123
TAA C + P + V LG ++LR+RE Q+ + ++ YD + D+MLL+L R
Sbjct: 59 TAAHC---KKPNLQ-VFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLAR 114
Query: 124 EANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQC 180
A L S I PLPL+ T C + GWG G FP + + + ++C
Sbjct: 115 PAKL--SELIQPLPLERDCSANTTSCHILGWGKTADGD----FPDTIQCAYIHLVSREEC 168
Query: 181 R--------PNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFT 230
N +C G C GD G PLVC G+ S+ PCG P +T
Sbjct: 169 EHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYT 228
Query: 231 RVALFRDWI 239
V + +WI
Sbjct: 229 NVCRYTNWI 237
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 104 bits (259), Expect = 8e-23
Identities = 76/249 (30%), Positives = 111/249 (44%), Gaps = 29/249 (11%)
Query: 4 LTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVM 63
+ VL+L+A A + +V G P+ A++ G CGG LIH +V+
Sbjct: 5 MVVLSLIAAAWAEEQN------KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVL 58
Query: 64 TAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDR 123
TAA C + P + V LG ++LR+RE Q+ + ++ YD + D+MLL+L R
Sbjct: 59 TAAHC---KKPNLQ-VFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLAR 114
Query: 124 EANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVN---VTVTPEDQC 180
A L S I PLPL+ T C + GWG G FP + + + ++C
Sbjct: 115 PAKL--SELIQPLPLERDCSANTTSCHILGWGKTADGD----FPDTIQCAYIHLVSREEC 168
Query: 181 R--------PNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFT 230
N +C G C GD G PLVC G+ S+ PCG P +T
Sbjct: 169 EHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYT 228
Query: 231 RVALFRDWI 239
V + +WI
Sbjct: 229 NVCRYTNWI 237
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 103 bits (256), Expect = 2e-22
Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 24/228 (10%)
Query: 29 GGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR 88
GG P P+ A++ QGR CGG L+H ++V+TAA C + G+ V LG + L R
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKE---GLK-VYLGKHALGR 93
Query: 89 RERQSRQTFSISSMSENGY-DPQQNLN---DLMLLQLDREANLTSSVTILPLPLQNATVE 144
E + + S+ Y +LN D+MLL+L LT + LPL N +
Sbjct: 94 VEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLS-HNNRLT 152
Query: 145 AGTRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQCR--------PNNVCTGVLTRRGG 195
GT C+V+GWG+ S + + N+ + +++CR N +C G T+ GG
Sbjct: 153 PGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAG--TKEGG 210
Query: 196 --ICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWI 239
C GD G PLVC +G+ S+ PCG+ P +TRV+ + WI
Sbjct: 211 KDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWI 258
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 101 bits (252), Expect = 5e-22
Identities = 80/245 (32%), Positives = 116/245 (47%), Gaps = 29/245 (11%)
Query: 27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86
I+GG + P P+LA+I G FC G+L+H +V++AA CF P S V+
Sbjct: 408 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 466
Query: 87 RRRERQSRQTFSISSMSE----NGYDPQQNLNDLMLLQL----DREANLTSSVTILPLPL 138
R QTF I + ++P +DL+L++L DR A + V + LP
Sbjct: 467 FNRTTDVTQTFGIEKYIPYTLYSVFNPSD--HDLVLIRLKKKGDRCATRSQFVQPICLPE 524
Query: 139 QNATVEAGTRCQVAGWGS-QRSGGRLSRFPRFVNVTVTPEDQC----------RPNNVCT 187
+T AG +CQ+AGWG + S R V + + +C PN +C
Sbjct: 525 PGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCA 584
Query: 188 GVLTRRGGICNGDGGTPLVCE--GLA--HGVASFSLGPCGR--GPDFFTRVALFRDWIDG 241
G + C GD G PL CE G+A +G+ S+ G CGR P +TRVA + DWI+
Sbjct: 585 GYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWIND 643
Query: 242 VLNNP 246
+ P
Sbjct: 644 RIRPP 648
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 100 bits (249), Expect = 1e-21
Identities = 73/255 (28%), Positives = 119/255 (46%), Gaps = 24/255 (9%)
Query: 1 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR 60
M L +L +A LA+ IVGG P+ S+ N G HFCGG+LI+ +
Sbjct: 1 MNPLLILTFVAAALAAPFDDDDK---IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQ 56
Query: 61 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ 120
+V++A C++S+ V LG +++ E + + + YD + ND+ML++
Sbjct: 57 WVVSAGHCYKSR----IQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIK 112
Query: 121 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPE 177
L A + + V+ + LP A GT+C ++GWG+ S G + +P + ++ V +
Sbjct: 113 LSSRAVINARVSTISLP--TAPPATGTKCLISGWGNTASSG--ADYPDELQCLDAPVLSQ 168
Query: 178 DQCR--------PNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDF 228
+C N C G L C GD G P+VC G GV S+ G + P
Sbjct: 169 AKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGV 228
Query: 229 FTRVALFRDWIDGVL 243
+T+V + WI +
Sbjct: 229 YTKVYNYVKWIKNTI 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,385,905
Number of Sequences: 37866
Number of extensions: 473344
Number of successful extensions: 1388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 879
Number of HSP's gapped (non-prelim): 186
length of query: 251
length of database: 18,247,518
effective HSP length: 100
effective length of query: 151
effective length of database: 14,460,918
effective search space: 2183598618
effective search space used: 2183598618
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.