Guide to the Human Genome
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Name: KLK3 Sequence: fasta or formatted (261aa) NCBI GI: 4502173
Description:

prostate specific antigen isoform 1 preproprotein

Referenced in:

Proteins Measured in Common Diagnostic Tests
Prostate
Serine Proteases

Other entries for this name:
alt prot [238aa] prostate specific antigen isoform 3 preproprotein
alt prot [218aa] prostate specific antigen isoform 4 preproprotein
alt prot [220aa] prostate specific antigen isoform 5 preproprotein
alt prot [69aa] prostate specific antigen isoform 6 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4         14           2
 C cysteine            3.8         10           1
 D aspartate           4.2         11           2
 E glutamate           4.2         11           2
 F phenylalanine       2.7          7           1
 G glycine             8.0         21           2
 H histidine           4.2         11           1
 I isoleucine          3.8         10           1
 K lysine              4.6         12           2
 L leucine            11.1         29           2
 M methionine          1.9          5           1
 N asparagine          1.9          5           1
 P proline             7.3         19           1
 Q glutamine           3.8         10           1
 R arginine            4.2         11           1
 S serine              8.0         21           2
 T threonine           5.7         15           2
 V valine             10.0         26           2
 W tryptophan          3.4          9           1
 Y tyrosine            1.5          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   prostate specific antigen isoform 1 preproprotein [Ho... 
KLK3                  0.805   prostate specific antigen isoform 5 preproprotein [H...
KLK3                  0.791   prostate specific antigen isoform 3 preproprotein [H...
KLK3                  0.791   prostate specific antigen isoform 4 preproprotein [H...
KLK2                  0.778   kallikrein 2, prostatic isoform 1 
KLK2                  0.583   kallikrein 2, prostatic isoform 2 
KLK1                  0.583   kallikrein 1 preproprotein 
KLK13                 0.381   kallikrein 13 precursor 
KLK11                 0.366   kallikrein 11 isoform 1 preproprotein 
KLK11                 0.366   kallikrein 11 isoform 2 precursor 
KLK11                 0.366   kallikrein 11 isoform 1 preproprotein 
KLK14                 0.340   kallikrein 14 preproprotein 
KLK5                  0.340   kallikrein-related peptidase 5 preproprotein 
KLK5                  0.340   kallikrein-related peptidase 5 preproprotein 
KLK5                  0.340   kallikrein-related peptidase 5 preproprotein 
KLK9                  0.340   kallikrein-related peptidase 9 
KLK8                  0.338   kallikrein 8 isoform 1 preproprotein 
PRSS1                 0.334   protease, serine, 1 preproprotein 
KLK8                  0.330   kallikrein 8 isoform 2 
KLK15                 0.330   kallikrein-related peptidase 15 isoform 4 preproprot...
PRSS3                 0.324   mesotrypsin isoform 2 preproprotein 
PRSS3                 0.321   mesotrypsin isoform 1 preproprotein 
KLK4                  0.317   kallikrein-related peptidase 4 preproprotein 
KLK6                  0.315   kallikrein-related peptidase 6 isoform A preproprote...
KLK6                  0.315   kallikrein-related peptidase 6 isoform A preproprotei...
PRSS2                 0.313   protease, serine, 2 preproprotein 
KLK7                  0.307   stratum corneum chymotryptic enzyme preproprotein [H...
KLK7                  0.307   stratum corneum chymotryptic enzyme preproprotein [Ho...
KLK12                 0.296   kallikrein 12 isoform 2 
KLK12                 0.283   kallikrein 12 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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